Please write clearly in block capitals. Centre number Candidate number Surname –––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Forename(s) –––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Candidate signature –––––––––––––––––––––––––––––––––––––––––––––––––––––––––– A-level HUMAN BIOLOGY Unit 5 The air we breathe, the water we drink, the food we eat Thursday 23 June 2016 Morning Time allowed: 2 hours Materials For this paper you must have: a ruler with millimetre measurements a calculator. Instructions Use black ink or black ball-point pen. Fill in the boxes at the top of this page. Answer all questions. You must answer the questions in the spaces provided. Do not write outside the box around each page or on blank pages. Do all rough work in this book. Cross through any work you do not want to be marked. Information The marks for questions are shown in brackets. The maximum mark for this paper is 90. You are expected to use a calculator, where appropriate. You will be marked on your ability to: – use good English – organise information clearly – use scientific terminology accurately. (JUN16HBIO501) WMP/Jun16/E6 HBIO5 Do not write outside the box 2 Answer all questions in the spaces provided. 1 (a) What is meant by the phenotype of an organism? [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ 1 (b) There is variation between phenotypes in a species. Two different types of factor can contribute to this variation. Name these two types of factor. [2 marks] 1 _____________________________________________________________________________ 2 _____________________________________________________________________________ 1 (c) What is meant by allopatric speciation? [2 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 5 (02) WMP/Jun16/HBIO5 Do not write outside the box 3 2 Complete the following passage about photosynthesis by writing the correct word or words in each of the blank spaces. [5 marks] Photosynthesis takes place in organelles called __________________________. There are two stages to the process. In the light-dependent stage energy is used in the production of _____________________ and__________________________________________. These two products are used in the light-independent stage to incorporate ___________________________________ from the atmosphere into ______________________________________________________________. As well as producing compounds that are the basis of all food chains, photosynthesis releases a gas, __________________________________, which is essential to human life. An increase in the amount of photosynthesis taking place may slow climate change because _____________________________________________________________________ . 5 Turn over for the next question Turn over 䊳 (03) WMP/Jun16/HBIO5 Do not write outside the box 4 3 (a) Figure 1 shows the typical carbon footprints for a person in Western Europe and a person in Africa. Figure 1 10000 Secondary contribution 9000 Primary contribution 8000 7000 Carbon footprint /kg CO2 per year 6000 5000 4000 3000 2000 1000 0 Western Europe 3 (a) (i) Africa Calculate how many times greater the carbon footprint is for a person from Western Europe than for a person from Africa. Show your working. [2 marks] ___________________ times greater (04) WMP/Jun16/HBIO5 Do not write outside the box 5 3 (a) (ii) The proportions of the primary and secondary contributions in the carbon footprints from Western Europe and Africa are different. Suggest why. [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ 3 (b) (i) In waste management, what do the letters BPEO stand for? [1 mark] ______________________________________________________________________________ 3 (b) (ii) Suggest two ways in which a household can contribute to the BPEO for waste management. [1 mark] 1 _____________________________________________________________________________ ______________________________________________________________________________ 2 _____________________________________________________________________________ ______________________________________________________________________________ 3 (b) (iii) Waste that cannot be disposed of in any other way is put into landfill sites. Organic waste in landfill sites can be converted into a fuel. Explain how. [2 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 7 Turn over 䊳 (05) WMP/Jun16/HBIO5 Do not write outside the box 6 4 (a) Erythromycin is an antibiotic that binds to the ribosomes of prokaryotic cells, but not to the ribosomes of eukaryotic cells. Because of this, erythromycin treats bacterial infections in people both effectively and safely. Explain why. [4 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ Between 2004 and 2011, scientists investigated the resistance of two species of bacteria to the antibiotic cephalosporin. They compared the percentage of patients infected with resistant forms of the two species of bacteria. Half of the patients were attending doctors’ surgeries and the other half were in hospital. The scientists’ results are shown in Table 1. Table 1 Percentage of patients infected with cephalosporin-resistant Escherichia coli bacteria Percentage of patients infected with cephalosporin-resistant Klebsiella pneumoniae bacteria 2004 2011 2004 2011 Patients attending doctors’ surgeries 0.9 5.7 0.8 3.1 Patients in hospitals 1.8 7.8 1.6 5.6 (06) WMP/Jun16/HBIO5 Do not write outside the box 7 4 (b) Suggest why the percentages of patients with antibiotic resistant bacteria 4 (b) (i) changed between 2004 and 2011 [2 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 4 (b) (ii) were higher in patients in hospital than in patients attending doctors’ surgeries. [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ 7 Turn over for the next question Turn over 䊳 (03) (07) WMP/Jun16/HBIO5 Do not write outside the box 8 5 (a) In people with asthma, symptoms occur after histamine binds to the surface of smooth muscle cells in the walls of the airways leading to the lungs. Some drugs used to treat asthma are molecules with a very similar shape to histamine. Suggest how these drugs work. [3 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 5 (b) Scientists recorded the number of cases of asthma and the amount of air pollution between 1976 and 1996. Each year they calculated the percentage changes in cases of asthma and amount of air pollution compared with the starting values in 1976. Figure 2 shows these changes. Figure 2 +400 +350 +300 Cases of asthma +250 Percentage +200 change from value +150 in 1976 +100 +50 0 Air pollution –50 1976 1978 1980 1982 1984 1986 1988 1990 1992 1994 1996 Year (08) WMP/Jun16/HBIO5 Do not write outside the box 9 5 (b) (i) A student who saw these data suggested that a decrease in air pollution caused an increase in the number of cases of asthma. Give two pieces of evidence from Figure 2 that do not support the student’s suggestion. [2 marks] 1 ____________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 2 ____________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 5 (b) (ii) Suggest two alternative explanations for the increase in the reported number of cases of asthma between 1976 and 1993. [2 marks] 1 ____________________________________________________________________________ ______________________________________________________________________________ 2 ____________________________________________________________________________ ______________________________________________________________________________ 7 Turn over for the next question Turn over 䊳 (09) WMP/Jun16/HBIO5 Do not write outside the box 10 6 (a) Ecologists studied a brown-field site from its creation until 20 years later. On five occasions, they recorded the types of plants and the number of species of invertebrate animals present on the site. Their results are shown in Table 2. Table 2 Time from creation of site / years Types of plants Number of species of invertebrate animals 1 Mosses 7 2 Mosses and short-lived flowering plants 19 3 Longer living non-woody flowering plants and grasses 31 10 Grasses, non-woody flowering plants and shrubs 74 20 Grasses, non-woody flowering plants, shrubs and trees 123 6 (a) (i) What is the name given to the series of changes shown in Table 2? [1 mark] ______________________________________________________________________________ 6 (a) (ii) Trees did not grow on the site until between 10 and 20 years after its creation. Suggest why. [3 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (10) WMP/Jun16/HBIO5 Do not write outside the box 11 6 (a) (iii) The number of species of invertebrate animals recorded changed during the 20-year period. Explain why. [3 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 6 (b) The ecologists determined the number of species of invertebrate animals by sampling areas of the site selected at random. Suggest two variables the ecologists would have controlled each time they carried out the sampling. [2 marks] 1 ____________________________________________________________________________ ______________________________________________________________________________ 2 ____________________________________________________________________________ ______________________________________________________________________________ 9 Turn over for the next question Turn over 䊳 (11) WMP/Jun16/HBIO5 Do not write outside the box 12 7 Ecologists investigated the number of small mammals killed by domestic cats in three areas of an English town. The cat population density was different in each of the three areas. The ecologists’ results are shown in Table 3. Table 3 Cat population density / number per km2 Number of small mammals killed by cats per year in each area A <300 2150 B 300 – 500 4950 C >500 2200 Area 7 (a) Describe how the numbers of small mammals killed by cats per year vary with the cat population density. Suggest explanations for these results. [4 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (12) WMP/Jun16/HBIO5 13 Question 7 continues on the next page DO NOT WRITE ON THIS PAGE ANSWER IN THE SPACES PROVIDED Turn over 䊳 (13) WMP/Jun16/HBIO5 Do not write outside the box 14 In another study, ecologists compared the percentages of the populations of different species of small mammals killed by cats in one area of an English town in one year. Their results are shown in Table 4. Table 4 Population Number born Number killed by Percentage of total per km2 Species of per km2 per cats per km2 per population killed by small mammal at the start of cats per year year year the year Grey squirrel 100 145 75 30.6 Wood mouse 2050 28 700 3200 10.4 Bank vole 620 5160 112 1.9 Brown rat 240 1340 114 7 (b) Table 4 is incomplete. Use data from the table to calculate the percentage of the total population of brown rats killed by cats per year. Show your working. [2 marks] Answer _____________ % 7 (c) Predation by cats affects the population sizes of these small mammals. On which of the populations in Table 4 does predation by cats have the greatest effect? Explain your answer. [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (14) WMP/Jun16/HBIO5 Do not write outside the box 15 7 (d) The ecologists collected their data from questionnaires that were filled in by the cats’ owners. The owners were asked to record the number of small mammals of each species killed by their cats each day. Suggest one possible source of error with this method of collecting data. [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 8 Turn over for the next question Turn over 䊳 (15) WMP/Jun16/HBIO5 Do not write outside the box 16 8 Figure 3 shows changes in the carbon dioxide concentration in the Earth’s atmosphere (atmospheric CO2 concentration) and the area of ice covering the surface of the sea (sea ice) around northern Europe between 1950 and 2010. Figure 3 400 Sea ice CO2 CO2 concentration in the 350 atmosphere / parts per million 300 1950 100 Area of sea ice / 50 arbitrary units 1960 1970 1980 1990 2000 0 2010 Year 8 (a) Explain two ways in which human activities may have contributed to the change in atmospheric CO2 concentration between 1950 and 2010. [4 marks] 1 ____________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 2 ____________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (16) WMP/Jun16/HBIO5 Do not write outside the box 17 8 (b) What term is given to the relationship between the two variables in Figure 3? [1 mark] ______________________________________________________________________________ 8 (c) Many scientists believe that the change in atmospheric CO2 concentration may have caused the change in the area of sea ice between 1950 and 2010. Suggest why. [3 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 8 (d) Grey seals are mammals that feed on fish in the seas around Britain and other parts of northern Europe. The population of grey seals in these seas has increased in recent years. Use information from Figure 3 to suggest one reason why. [2 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 10 Turn over for the next question Turn over 䊳 (03) (17) WMP/Jun16/HBIO5 Do not write outside the box 18 9 Scientists recorded the number of new cases of cancer per year in different age groups. Their data are shown in Figure 4. Figure 4 2500 2000 Number of 1500 new cases of cancer per 100 000 1000 people per year 500 0 0-4 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-69 70-74 75-79 80-84 85-89 Age group / years 9 (a) The number of cases of cancer is recorded as the number per 100 000 of each age group. Give one reason why. [1 mark] ______________________________________________________________________________ ______________________________________________________________________________ 9 (b) The scientists suggested two explanations for the differences between the age groups: 9 (b) (i) environmental factors natural selection affecting the frequency of some alleles that lead to cancer. Explain how environmental factors could cause the differences between age groups in the number of new cancer cases. [2 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (18) WMP/Jun16/HBIO5 Do not write outside the box 19 9 (b) (ii) Explain how natural selection could lead to the difference in the number of new cancer cases in different age groups. [4 marks] ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 7 Turn over for the next question Turn over 䊳 (19) WMP/Jun16/HBIO5 Do not write outside the box 20 ESSAY You should write your essay in continuous prose. Your essay will be marked for its scientific accuracy. It will also be marked for your selection of relevant material from different parts of the specification and for the quality of your written communication. The maximum number of marks that can be awarded is: Scientific content Breadth of knowledge Relevance Quality of written communication 10 16 3 3 3 Write an essay on one of the topics below. Either 10 (a) The shapes of molecules are important in human life. [25 marks] Or 10 (b) Biotic and abiotic environmental factors affect human health in many ways. [25 marks] END OF QUESTIONS If you want to make a plan write it here. ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ (20) WMP/Jun16/HBIO5 Do not write outside the box 21 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