LTQ Series
Preinstallation Requirements
Guide
97055-97170 Revision A
January 2009
© 2009 Thermo Fisher Scientific Inc. All rights reserved.
Xcalibur, Surveyor, and Accela are registered trademarks of Thermo Fisher Scientific Inc. in the United States.
LXQ, LTQ XL, and IonMax are trademarks of Thermo Fisher Scientific Inc.
The following are registered trademarks in the United States and other countries: Windows is a registered
trademark of Microsoft Corporation. Swagelok is a registered trademark of the Crawford Fitting Company.
Dranetz is a registered trademark of Dranetz Technologies, Inc. Styrofoam is a registered trademark of Dow
Chemical Company. Teflon is a registered trademark of E. I. du Pont de Nemours & Co. Tygon is a registered
trademark of Norton Company. ProteoMass and Supelco are registered trademarks of Sigma-Aldrich
Biotechnology LP and Sigma-Aldrich Co.
All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in the
product operation. This document is copyright protected and any reproduction of the whole or any part of this
document is strictly prohibited, except with the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice. All technical information in this
document is for reference purposes only. System configurations and specifications in this document supersede
all previous information received by the purchaser.
Thermo Fisher Scientific Inc. makes no representations that this document is complete, accurate or errorfree and assumes no responsibility and will not be liable for any errors, omissions, damage or loss that might
result from any use of this document, even if the information in the document is followed properly.
This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a purchaser. This
document shall in no way govern or modify any Terms and Conditions of Sale, which Terms and Conditions of
Sale shall govern all conflicting information between the two documents.
Release history: Revision A released January 2009.
Software version: Xcalibur 2.0.7 or higher, MALDI Source 2.5.0, LTQ Series 2.5
For Research Use Only. Not regulated for medical or veterinary diagnostic use by U.S. Federal Drug
Administration or other competent authorities.
Regulatory Compliance
Thermo Fisher Scientific performs complete testing and evaluation of its products to ensure full compliance with
applicable domestic and international regulations. When the system is delivered to you, it meets all pertinent
electromagnetic compatibility (EMC) and safety standards as described in the next section or sections by product name.
Changes that you make to your system may void compliance with one or more of these EMC and safety standards.
Changes to your system include replacing a part or adding components, options, or peripherals not specifically
authorized and qualified by Thermo Fisher Scientific. To ensure continued compliance with EMC and safety standards,
replacement parts and additional components, options, and peripherals must be ordered from Thermo Fisher Scientific
or one of its authorized representatives.
Regulatory compliance results for the followingThermo Scientific products:
•
LXQ (February 2005)
•
LTQ XL (September 2006)
•
LTQ XL/ETD System (January 2007)
•
MALDI LTQ XL System (August 2007)
LXQ (February 2005)
EMC - Directives 89/336/EEC as amended by 92/31/EEC and 93/68/EEC
EMC compliance has been evaluated by U.L. Underwriter’s Laboratory Inc.
EN 55011: 1998
EN 61000-4-3: 2002, A1: 2002
EN 61000-3-2: 1995, A1: 1998, A2: 1998, A14: 2000
EN 61000-4-4: 1995, A1: 2001, A2: 2001
EN 61000-3-3: 1995
EN 61000-4-5: 1995, A1: 2001
EN 61326-1: 1997
EN 61000-4-6: 1996, A1: 2001
EN 61000-4-2: 1995, A1: 1998, A2: 2001
EN 61000-4-11: 1994, A1: 2001
FCC Class A, CFR 47 Part 15, Subpart B: 2004
CISPR 11: 1999, A1: 1999, A2: 2002
Low Voltage Safety Compliance
Compliance with safety issues is declared under Thermo Fisher Scientific sole responsibility. This device complies with
Low Voltage Directive 73/23/EEC and harmonized standard EN 61010-1:2001.
LTQ XL (September 2006)
EMC Directives 89/336/EEC
EMC compliance has been evaluated by TUV Rheinland of North America, Inc.
EN 55011: 1998, A1: 1999, A2: 2002
EN 61000-4-3: 2002
EN 61000-3-2: 1995, A1: 1998, A2: 1998, A14: 2000
EN 61000-4-4: 1995, A1: 2001, A2: 2001
EN 61000-3-3: 1995, A1:2001
EN 61000-4-5:1995, A1: 2001
EN 61326-1: 1997, A1: 1998, A2: 2001, A3: 2003
EN 61000-4-6: 2003
EN 61000-4-2: 2001
EN 61000-4-11: 2001
FCC Class A, CFR 47 Part 15: 2005
CISPR 11: 1999, A1: 1999, A2: 2002
Low Voltage Safety Compliance
Compliance with safety issues is declared under Thermo Fisher Scientific sole responsibility. This device complies with
Low Voltage Directive 73/23/EEC and harmonized standard EN 61010-1:2001.
LTQ XL/ETD System (January 2007)
EMC Directives 89/336/EEC
EMC compliance has been evaluated by TUV Rheinland of North America, Inc.
EN 61000-3-2: 1995, A1: 1998, A2: 1998, A14: 2000
EN 61000-4-4:1995, A1: 2000, A2:2001
EN 61000-3-3: 1995, A1:2001
EN 61000-4-5: 1995, A1: 2001
EN 61326-1: 1997, A1:1998, A2:2001, A3:2003
EN 61000-4-6: 2003
EN 61000-4-2: 2001
EN 61000-4-11: 1994, A1: 2001
EN 61000-4-3: 2002
CISPR 11: 1999, A1: 1999, A2: 2002
FCC Class A, CFR 47 Part 15: 2005
Low Voltage Safety Compliance
Compliance with safety issues is declared under Thermo Fisher Scientific sole responsibility. This device complies with
Low Voltage Directive 73/23/EEC and harmonized standard EN 61010-1:2001.
MALDI LTQ XL System (August 2007)
EMC Directives 2004/108/EC
EMC compliance has been evaluated by TUV Rheinland of North America.
EN 55011: 1998, A1: 1999, A2: 2002
EN 61000-4-3: 2002
EN 61000-3-2: 2000
EN 61000-4-4: 1995, A1: 2000, A2: 2001
EN 61000-3-3: 1995, A1: 2001
EN 61000-4-5: 2001
EN 61326-1: 1998, A2: 2001, A3: 2003
EN 61000-4-6: 2003
EN 61000-4-2: 2001
EN 61000-4-11: 2001
FCC Class A, CFR 47 Part 15: 2006
CISPR 11: 1998, A1:1999, A2: 2002
Low Voltage Safety Compliance
Compliance with safety issues is declared under Thermo Fisher Scientific sole responsibility. This device complies with
Low Voltage Directive 2006/95/EC and harmonized standard EN 61010-1:2001.
Safety of Laser Products
Compliance with safety of laser products is declared under Thermo Fisher Scientific sole responsibility. This device
complies with the harmonized standard IEC/EN 60825-1/A2: 2001.
FCC Compliance Statement
THIS DEVICE COMPLIES WITH PART 15 OF THE FCC RULES. OPERATION IS SUBJECT TO
THE FOLLOWING TWO CONDITIONS: (1) THIS DEVICE MAY NOT CAUSE HARMFUL
INTERFERENCE, AND (2) THIS DEVICE MUST ACCEPT ANY INTERFERENCE RECEIVED,
INCLUDING INTERFERENCE THAT MAY CAUSE UNDESIRED OPERATION.
CAUTION Read and understand the various precautionary notes, signs, and symbols contained inside
this manual pertaining to the safe use and operation of this product before using the device.
Notice on Lifting and Handling of
Thermo Scientific Instruments
For your safety, and in compliance with international regulations, the physical handling of this Thermo Fisher Scientific
instrument requires a team effort to lift and/or move the instrument. This instrument is too heavy and/or bulky for one
person alone to handle safely.
Notice on the Proper Use of
Thermo Scientific Instruments
In compliance with international regulations: Use of this instrument in a manner not specified by Thermo Fisher
Scientific could impair any protection provided by the instrument.
Notice on the Susceptibility
to Electromagnetic Transmissions
Your instrument is designed to work in a controlled electromagnetic environment. Do not use radio frequency
transmitters, such as mobile phones, in close proximity to the instrument.
For manufacturing location, see the label on the instrument.
Important Preinstallation Information... PLEASE READ
LTQ Series Installation Request
Dear User,
Read the LTQ Series Preinstallation Requirements Guide. Print and complete this installation request. After all items on this request
are fulfilled, sign and date the form. Then mail, fax, or E-mail this form to your local Thermo Fisher Scientific sales/service office.
The information for your nearest office is located on the following pages.
‰ 1. All laboratory remodeling has been completed.
‰ 2. LTQ Series system is on site.
‰ 3. Principal operator will be available during the installation
/ certification period.
‰ 4. Doorways, hallways, and so on are a minimum width of
94 cm (37 in.)
‰ 5. Available floor area is sufficient and flooring will support
the load.
‰ 6. Sufficient bench space is available for all of the
equipment. List the following:
Width: _________________________________
Depth: _________________________________
Height: _________________________________
‰ 7. Workbench can support the weight of the system
(approximately 202 kg (445 lbs)) and is free from
vibration.
‰ 8. Lighting is adequate.
‰ 9. Main power is installed and is in compliance with local
electrical codes.
‰ 10. Power for test and cleaning equipment is installed.
‰ 11. Power outlets are of the correct configuration. Note
NEMA type: _____________________________
‰ 12. Voltage of power outlet has been measured. Note
measured voltage:
ac input to ground: ________
Neutral to ground: ________
ac input to neutral: ________
‰ 13. Power is free from fluctuations due to slow changes in the
average voltage or changes due to surges, sags, or
transients.
‰ 14. Air conditioning is adequate for temperature, humidity,
and particulate matter control. The laboratory can be
maintained at a constant temperature, between 15 and
27 °C (59 and 81 °F).
‰ 15. Relative humidity is between 40 and 80% with no
condensation.
‰ 16. System work area is free from magnetic disruption and
electrostatic discharge.
‰ 17. All gases required (helium and nitrogen) are on site, gas
lines are installed, and appropriate gas regulators are
available.
Gases and purity:
Nitrogen: _______%
Helium: ________%
Additional UHP gas source for the ETD module only:
75% nitrogen/25% helium mixture: ________%
OR 100% Nitrogen: _______%
‰ 18. New or recently cleaned HPLC system is available that
produces pulse-free, continuous flow from 100 to 1000
μL/min.
‰ 19. HPLC-grade water, methanol, acetonitrile, and
isopropyl alcohol are available for testing the
performance of your instrument.
‰ 20. There is a suitable exhaust system present that is
separate from solvent waste. You must provide one
exhaust system for the API source and a second exhaust
system for the forepump.
‰ 21. Provision has been made for collecting solvent waste
from the API source.
‰ 22. One voice telephone line is installed near the system.
‰ 23. All relevant safety regulations are complied with.
‰ 24. For a MALDI LTQ XL system, you have specified an
appropriate delivery site for the chemical kit.
‰ 25. The following equipment and materials are necessary
for proper installation of your MALDI source. They are
also required for many routine operational tasks
described in the MALDI Source Getting Started Guide.
Equipment:
- Sonicator bath large enough to hold 1 L beaker
- Microcentrifuge
- Vortexer
- Pipettors (2.5 μL, 200 μL, and 1000 μL)
recommended; additional sizes might be useful
- Analytical balance
Consumables:
- Microcentrifuge tubes (500 μL)
- Tips for pipettors
- Optical lens wipes or soft clean room wipes
- Can of compressed difluoroethane (sold as
“compressed air” for dust removal)
Chemical and Solvents:
- Water
- Isopropyl alchohol
- Methanol
- Acetonitrile
- Acetone
- Trifluoroacetic acid (TFA)
- 20 to 30% ammonium hydroxide solution
CONTINUED ON THE BACK OF THIS PAGE
LTQ Series Installation Request - Continued
Have any special acceptance specifications been agreed to in the contract?
If YES, attach full details of specifications.
Yes ‰ No ‰
Is there any additional equipment that needs to be interfaced to the system?
If YES, attach full details of additional equipment.
Yes ‰ No ‰
Note: We reserve the right to invoice against the Thermo Fisher Scientific field service engineer’s time if the installation requirements
are not met on the date of the installation.
Print your information clearly below
Name _______________________________________________________________
E-mail address _________________________________________________________
Company ____________________________________________________________Telephone_______________________
Address _____________________________________________________________________________________________
Address _____________________________________________________________________________________________
City ______________________________________ State/Province ______________Country ________________________
Sales order number________________________________
Signature _____________________________________________________________Date ___________________________
Offices for Thermo Fisher Scientific San Jose Products
United States
Germany
Fax.........+1 561 688 8731
E-mail [email protected]
Im Steingrund 4-6
D-63303 Dreieich
Phone.... +49 6103 408 1050
Fax ........ +49 6103 408 1213
E-mail ... [email protected]
Canada
2845 Argentia Road, Unit 4
Mississauga, Ontario
L5N 8G6
Phone ....+1 800 530 8447
Fax.........+1 905 890 5775
E-mail [email protected]
Italy
Strada Rivoltana
I-20090 Rodano (Milano)
Phone.... Numero Verde 800823162
Fax ........ +39 2 950 59 225
E-mail ... [email protected]
Netherlands
Europe
Austria
Wehlistrasse 27b
A-1200 Wien
Phone ....+43 1 333 50340
Fax.........+43 1 333 503426
E-mail [email protected]
Belgium
Z3 Doornveld 172
1731 Zellik
Phone ....+32 2 482 30 30
Fax.........+32 2 482 30 31
E-mail [email protected]
Denmark
Fruebjergvej 3
2100 KØbenhavn Ø
Phone ....+45 2 70 23 62 60
Fax.........+45 2 70 23 62 63
E-mail [email protected]
France
(also representing French speaking North Africa, Algeria,
Morocco, and Tunisia)
16 Avenue du Québec
Silic 765
Z.A. de Courtaboeuf
F-91963 Les Ulis Cédex
Phone ....+33 1 60 92 48 00
Fax.........+33 1 60 92 49 00
E-mail [email protected]
Takkebijsters 1
NL-4817 BL Breda
Phone.... +31 76 579 55 55
Fax ........ +31 76 571 41 71
E-mail ... [email protected]
Spain
Valportillo I, 22 1a Planta, Edificio Caoba
ES-28108 Alcobendas (Madrid)
Phone.... +34 914 845 965
Fax ........ +34 914 843 598
E-mail ... [email protected]
Spain
Acer 30-32
Edificio Sertram – Planta 2, Modulo 3
ES-08038 (Barcelona)
Phone.... +34 93 223 0918
Fax ........ +34 93 223 0982
E-mail ... [email protected]
Sweden, Norway, and Finland
Pyramidbacken 3
SE-141 75 Kungens Kurva (Stockholm)
Phone.... +46 8 556 468 00
Fax ........ +46 8 556 468 08
E-mail ... [email protected]
Switzerland
Neuhofstrasse 11
4153 Reinach
Phone.... +41 61716 77 00
Fax ........ +41 61716 77 20
E-mail ... [email protected]
Offices for Thermo Fisher Scientific San Jose Products - Continued
Europe - continued
Australasia and Asia
United Kingdom
Australia
Stafford House
1 Boundary Park
Boundary Way
Hemel Hempstead
Hertfordshire HP2 7GE
Phone ...+44 1442 233 555
Fax.........+44 1442 233 667
E-mail [email protected]
P.O. Box 239 Rydalmere
Unit 14, 38 - 46 South Street
Rydalmere, N.S.W. 2116
Phone.... +61 2 8844 9500
Fax ........ +61 2 8844 9599
E-mail ... [email protected]
Other Europe, Middle East, and Africa
C-2F 3-9 Moriya-cho, Kanagawa-ku
Yokohama, Kanagawa 221-0022
Phone.... +81 45 453 9197
Fax ........ +81 45 453 9235
E-mail ... [email protected]
Wehlistrasse 27b
A-1200 Wien
Phone ....+43 1 333 50 34 0
Fax.........+43 1 333 50 34 26
E-mail [email protected]
Japan
Japan
6F, Ryokuchi-eki Building
2-4-1 Terauchi, Toyonaka City
Osaka 561-0872
Phone.... +81 6 6863-1551
Fax ........ +81 6 6863-1096
E-mail ... [email protected]
P.R. China
Rm. 702-715, 7F Tower West, Younghe Plaza
No. 28, Andingmen East Street
Beijing 100007
Phone.... 800 810 5118, 400 650 5118 (Free lines)
Fax ........ +86 10 88370548
E-mail ... [email protected]
P.R. China
Building 6
No. 27 Xin Jin Qiao Road
Shanghai 201206m
Phone.... 800 810 5118, 400 650 5118 (Free lines)
Fax ........ +86 21 64457830
E-mail ... [email protected]
WEEE Compliance
This product is required to comply with the European Union’s Waste Electrical & Electronic
Equipment (WEEE) Directive 2002/96/EC. It is marked with the following symbol:
Thermo Fisher Scientific has contracted with one or more recycling or disposal companies in each
European Union (EU) Member State, and these companies should dispose of or recycle this product.
See www.thermo.com/WEEERoHS for further information on Thermo Fisher Scientific’s compliance
with these Directives and the recyclers in your country.
WEEE Konformität
Dieses Produkt muss die EU Waste Electrical & Electronic Equipment (WEEE) Richtlinie 2002/96/EC
erfüllen. Das Produkt ist durch folgendes Symbol gekennzeichnet:
Thermo Fisher Scientific hat Vereinbarungen mit Verwertungs-/Entsorgungsfirmen in allen EUMitgliedsstaaten getroffen, damit dieses Produkt durch diese Firmen wiederverwertet oder entsorgt
werden kann. Mehr Information über die Einhaltung dieser Anweisungen durch Thermo Fisher
Scientific, über die Verwerter, und weitere Hinweise, die nützlich sind, um die Produkte zu
identifizieren, die unter diese RoHS Anweisung fallen, finden sie unter www.thermo.com/
WEEERoHS.
Conformité DEEE
Ce produit doit être conforme à la directive européenne (2002/96/EC) des Déchets d'Equipements
Electriques et Electroniques (DEEE). Il est marqué par le symbole suivant:
Thermo Fisher Scientific s'est associé avec une ou plusieurs compagnies de recyclage dans chaque état
membre de l’union européenne et ce produit devrait être collecté ou recyclé par celles-ci. Davantage
d'informations sur la conformité de Thermo Fisher Scientific à ces directives, les recycleurs dans votre
pays et les informations sur les produits Thermo Fisher Scientific qui peuvent aider la détection des
substances sujettes à la directive RoHS sont disponibles sur www.thermo.com/WEEERoHS.
C
Contents
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xv
Related Documentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
Safety and Special Notices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xvi
Contacting Us . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xvii
Thermo Scientific
Chapter 1
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Chapter 2
Site Preparation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
Data System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
LXQ or LTQ XL System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Entrance Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Space and Load Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Electrical Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
LTQ XL/ETD System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Entrance Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Space and Load Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Electrical Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
MALDI LTQ XL System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Entrance Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Space and Load Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Electrical Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Forepumps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Telephone . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Chapter 3
Operating Environment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Temperature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21
Humidity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Vibration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Lighting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Particulate Matter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Electrostatic Discharge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Chapter 4
Line Power . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Quality of Power . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Power Monitoring Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Power Conditioning Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
LTQ Series Preinstallation Requirements Guide
xiii
Contents
Available Outlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Connecting the Modules to Wall Outlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
Uninterruptible Power Supply. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
Technical Assistance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Chapter 5
Gases and Solvents. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35
Fittings and Parts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Gases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Helium . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Nitrogen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
ETD Reagent Carrier Gas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
Solvent Recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Chapter 6
Waste and Exhaust . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
Exhaust System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
Solvent Waste . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44
Chapter 7
Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .45
Installation Kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
LXQ Accessory Kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
LTQ XL Accessory Kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
LTQ XL/ETD System Kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
Fluoranthene for the LTQ XL/ETD System . . . . . . . . . . . . . . . . . . . . . . . . . 47
MALDI LTQ XL System Kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Required Chemical and Accessory Kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
Optional Accessory Kits. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
MALDI-Specific Equipment, Consumables, and Solvents . . . . . . . . . . . . . . . 48
Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Preventive Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Chapter 8
Instrument Shipments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .51
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .53
xiv
LTQ Series Preinstallation Requirements Guide
Thermo Scientific
P
Preface
This preinstallation requirements guide provides information to assist in planning and
preparing your lab site prior to delivery and installation. Read each section carefully to be sure
that your laboratory is ready for installation of your mass spectrometry system.
The LTQ Series includes the following Thermo Scientific mass spectrometers:
• The LXQ™, a 2D linear ion trap mass spectrometer.
• The LTQ XL™, a 2D linear ion trap mass spectrometer.
• The LTQ XL/ETD system where the ETD module is physically coupled to the back of
the LTQ XL MS detector.
• The MALDI LTQ XL system with the MALDI sample and control modules connected.
The optional API kit provides the hardware for LC/MS applications with ESI, APCI, and
so forth.
Related Documentation
In addition to this guide, Thermo Fisher Scientific provides the following documentation for
the LTQ Series ion trap mass spectrometers:
• A printed copy of the Safety and Regulatory Guide
The Safety and Regulatory Guide contains important safety information about Thermo
Scientific mass spectrometry and liquid chromatography systems. This document is
shipped with every Thermo Scientific mass spectrometer and liquid chromatography
device.
• PDF files of the documents in Table 1 that you can access from the data system computer
Table 1. LTQ Series MS documentation (Sheet 1 of 2)
Thermo Scientific
Model
Related Documents
LXQ
LXQ Getting Started Guide
LXQ Hardware Manual
LTQ XL
LTQ XL Getting Started Guide
LTQ XL Hardware Manual
LTQ Series Preinstallation Requirements Guide
xv
Preface
Table 1. LTQ Series MS documentation (Sheet 2 of 2)
Model
Related Documents
LXQ, LTQ XL,
LTQ XL/ETD system,
MALDI LTQ XL system
LTQ Series Getting Connected Guide
ETD module
ETD Module Getting Started Guide
ETD Module Hardware Manual
MALDI source
MALDI Source Getting Started Guide
MALDI Source Hardware Manual
API Source
Ion Max and Ion Max-S API Source Hardware Manual
To access the manuals for the mass spectrometer, from the Windows™ XP taskbar, choose
Start > All Programs > Xcalibur > Manuals > Brand name of mass spectrometer and then click
the listing for the PDF that you want to view. The software also provides Help. To access the
Help, choose Help from the menu bar or click the
button on the toolbar.
Safety and Special Notices
Make sure you follow the precautionary statements presented in this guide. The safety and
other special notices appear in boxes.
Safety and special notices include the following:
CAUTION Highlights hazards to humans, property, or the environment. Each CAUTION
notice is accompanied by an appropriate CAUTION symbol.
IMPORTANT Highlights information necessary to prevent damage to software, loss of
data, or invalid test results; or might contain information that is critical for optimal
performance of the system.
Note Highlights information of general interest.
Tip Highlights helpful information that can make a task easier.
xvi
LTQ Series Preinstallation Requirements Guide
Thermo Scientific
Preface
Contacting Us
There are several ways to contact Thermo Fisher Scientific for the information you need.
To contact Technical Support
Phone
Fax
E-mail
Knowledge base
800-532-4752
561-688-8736
[email protected]
www.thermokb.com
Find software updates and utilities to download at mssupport.thermo.com.
To contact Customer Service for ordering information
Phone
Fax
E-mail
Web site
800-532-4752
561-688-8731
[email protected]
www.thermo.com/ms
To copy manuals from the Internet
Go to mssupport.thermo.com and click Customer Manuals in the left margin of the
window.
To suggest changes to documentation or to Help
• Fill out a reader survey online at www.thermo.com/lcms-techpubs.
• Send an e-mail message to the Technical Publications Editor at
[email protected].
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
xvii
1
Introduction
Thermo Scientific mass spectrometers operate under carefully controlled environmental
conditions.
The purchaser is responsible for providing a suitable location and operating environment, a
source of power of acceptable quality, correct gas and solvent supplies, and proper waste and
exhaust systems.
CAUTION Operating a system or maintaining it outside the power and operating
environment specifications described in this guide might cause failures of many types. The
repair of such failures is specifically excluded from the standard warranty and service
contract coverage.
For additional information, request specific preinstallation support directly through your local
Thermo Fisher Scientific office.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
1
2
Site Preparation
Before a Thermo Fisher Scientific field service engineer can install your instrument, you must
prepare the site. Transport of the equipment to the site requires wide entrances and hallways.
Supporting the weight of the MS detector, computer, and liquid chromatography (LC) system
requires large and strong workbenches. Each system also has specific power requirements. You
must install a telephone within reach of the workbench.
It is your responsibility to provide an acceptable installation site.
Contents
• Data System
• LXQ or LTQ XL System
• LTQ XL/ETD System
• MALDI LTQ XL System
• Forepumps
• Telephone
CAUTION If the instrument shipping container, Shock Watch, or other indicators show
any evidence of damage or mishandling during shipment, do NOT open the container.
Call your Thermo Fisher Scientific representative for instructions on what to do. If there
is no evidence of shipping damage or mishandling, then you can proceed with the
instructions that follow.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
3
2
Site Preparation
Data System
Data System
For all LTQ Series mass spectrometers, use one workbench to hold the data system computer,
monitor, and printer. This workbench must have minimum dimensions of 1 × 1.22 m
(3 × 4 ft) and be capable of supporting the weight of the data system and printer
[48 kg (105 lb)]. Because the Ethernet communication cables between the Ethernet switch
and the mass spectrometer or optional LC system components must be no longer
than 3 m (10 ft) each, the workbench that holds the data system must be located next to the
workbench or workbenches that hold the mass spectrometer and optional LC system.
CAUTION To ensure compliance with safety and EMC regulations, use category 5,
shielded Ethernet cables no longer than 3 m (10 ft) in length.
See Table 1 and Figure 1 for the space requirements and weights of the typical data system
hardware components.
Table 1. Typical data system hardware components space and load requirements
Height
Depth
Weight
Module
cm
in.
cm
in.
cm
in.
kg
lb
Minitower computer
48
19
18
7
43
17
14
30
Monitor
41
16
41
16
43
17
17
38
Keyboard
5
2
48
19
20
8
1
2
20
8
41
16
46
18
7
16
Laser printer*
* Approximate.
4
Width
LTQ Series Preinstallation Requirements Guide
The actual values depend on your equipment.
Thermo Scientific
2
Figure 1.
Site Preparation
Data System
Typical data system workbench
122 cm
(48 in.)
Ethernet
switch
Monitor
Computer
Printer
76 cm
(30 in.)
Ethernet communication
cables (connected to the
mass spectrometer and
optional LC system)
Wall outlet for
data system components
120 or 230 V ac
Because a scanner is supplied with the tissue imaging kit available for the MALDI system, a
larger workbench is required. See Table 2 and Figure 2 for the space requirements and weights
of the typical data system hardware components that includes a scanner for MALDI tissue
imaging.
Table 2. Data system hardware components space and load requirements including scanner for
MALDI tissue imaging
Height
*
Thermo Scientific
Width
Depth
Weight
Module
cm
in.
cm
in.
cm
in.
kg
lb
Minitower computer
48
19
18
7
43
17
14
30
Monitor
41
16
41
16
43
17
17
38
Keyboard
5
2
48
19
20
8
1
2
Laser printer*
20
8
41
16
46
18
7
16
Scanner
10
4
30
12
50
20
30
12
Approximate. The actual value depends on your equipment.
LTQ Series Preinstallation Requirements Guide
5
2
Site Preparation
Data System
Figure 2.
Data system workbench including the scanner for the MALDI tissue imaging kit
152 cm
(60 in.)
Ethernet
switch
Ethernet
communication cables
(connected to the
mass spectrometer
and optional
LC system)
Monitor
Computer
Printer
Scanner
76 cm
(30 in.)
Wall outlet for
data system components
120 or 230 V ac
See Table 3 for the data system power requirements.
Table 3. Data system suggested power connections (with printer) at 120 or 230 V ac
Monitor
Computer
Laser printer*
Total
120 V ac
2A
4A
3A
9A
230 V ac
1A
2A
2A
5A
* Approximate.
6
LTQ Series Preinstallation Requirements Guide
The actual value depends on your equipment.
Thermo Scientific
2 Site Preparation
LXQ or LTQ XL System
LXQ or LTQ XL System
Entrance Requirements
The LTQ Series mass spectrometer and accessories are shipped in a container with the
following dimensions: l 102 cm (40 in.), w 92 cm (36 in.), h 117 cm (46 in.). The container
and its contents weigh approximately 160 kg (350 lb). Other modules—such as the
computer, forepump, monitor, and options—are shipped in their own containers. Their
dimensions and weights are less than that of the container for the mass spectrometer.
Space and Load Requirements
For the LXQ or LTQ XL system, use one workbench to hold the mass spectrometer, the LC,
and any other MS/LC options. This workbench must have minimum dimensions of
1 × 1.53 m (3 × 5 ft) and be capable of supporting the weight of the mass spectrometer
[105 kg (230 lbs)] plus the weight of the liquid chromatograph and any options. Allow about
8 cm (3 in.) of clear space behind the system for proper air circulation and for clearance of the
gas lines and electrical connections. Also allow at least 92 cm (36 in.) of vertical clearance
between the top of the mass spectrometer and any shelves above it.
See Table 4 for the space requirements and weights for the LXQ or LTQ XL mass
spectrometer and LC system.
Table 4. LXQ and LTQ XL space and load requirements
Height
Width
Depth
Weight
Module
cm
in.
cm
in.
cm
in.
kg
lb
LXQ or LTQ XL MS detector
56
22
76
30
59
23
105
230
Liquid chromatograph*
73
30
38
15
51
20
67
147
Forepump (each)
30
12
20
7
64
25
34
75
* The space and weight requirements listed for the liquid chromatograph are those for a system containing an Accela
Pump, Accela Autosampler, and Accela PDA detector. Allow additional height clearance for the solvent platform
and solvent bottles.
Note For your safety, Thermo Fisher Scientific recommends that the load rating for the
table where you place the LXQ or LTQ XL MS detector and LC unit be at least twice the
weight of the equipment placed on that table.
Figure 3 shows the workbench for an LXQ system that uses one forepump.
CAUTION Figure 3 and Figure 4 do not show the solvent drainage system for the LC
system. For information on the Accela or Surveyor Plus™ LC drainage systems, refer to the
Getting Connected Guides for these Thermo Scientific LC systems.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
7
2
Site Preparation
LXQ or LTQ XL System
Figure 3.
Workbench for LXQ system with an Accela LC system
38 cm
(15 in.)
76 cm
(30 in.)
Accela
LC system
LXQ
mass spectrometer
10 cm
(4 in.)
PDA detector
114 cm
(45 in.)
APDACCELA
Detector
Power
Communication
Run
Lamps
Power
Communication
Run
Temperature
Power
Communication
Run
Degas
Autosampler
Category 5,
shielded
Ethernet cables
AAutosampler
CCELA
Accela pump
ACCELA
Pump
Data system
workbench
Wall outlet #1
for LC system
120 or 230 V ac
External vent for the
forepump exhaust
Solvent trap
Forepump with
noise reduction cover
Wall outlet #2
for mass spectrometer
230 V ac (only)
External vent for the
solvent trap connected
to the API source
8
LTQ Series Preinstallation Requirements Guide
Thermo Scientific
2 Site Preparation
LXQ or LTQ XL System
Figure 4 shows the workbench for an LTQ XL system with two forepumps.
Figure 4.
Workbench for LTQ XL mass spectrometer with optional LC system
38 cm
(15 in.)
76 cm
(30 in.)
Accela
LC system
LTQ XL
mass spectrometer
10 cm
(4 in.)
PDA detector
114 cm
(45 in.)
APDACCELA
Detector
Power
Communication
Run
Lamps
Power
Communication
Run
Temperature
Power
Communication
Run
Degas
Autosampler
Category 5,
shielded
Ethernet cables
AAutosampler
CCELA
Accela pump
ACCELA
Pump
Data system
workbench
Wall outlet #1
for LC system
120 or 230 V ac
External vent for the
forepump exhaust
Solvent trap
Forepumps with
noise reduction cover
Wall outlet #2
for mass spectrometer
230 V ac
External vent for the
solvent trap connected
to the API source
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
9
2
Site Preparation
LXQ or LTQ XL System
Electrical Requirements
The outlet power requirements in Table 5 are based on the workbench setup for the LXQ
shown in Figure 3 on page 8 and for the LTQ XL shown in Figure 4 on page 9.
Table 5. Power requirements for an LC and an LXQ or LTQ XL MS detector
Outlet #1
Liquid chromatograph*
Outlet #2
LXQ MS detector
120 V ac
10 A
N/A
N/A
230 V ac
5A
10 A
15 A
* Approximate.
10
LTQ Series Preinstallation Requirements Guide
OR
Outlet #2
LTQ XL MS detector
The actual value depends on your equipment.
Thermo Scientific
2
Site Preparation
LTQ XL/ETD System
LTQ XL/ETD System
Entrance Requirements
The entrance to your facility and the width of all hallways, elevators, and so on must be a
minimum of 94 cm (37 in.).1 However, additional room must be allowed for maneuvering
the system around corners, into elevators, or through doorways.
The LTQ Series mass spectrometer and accessories are shipped in a container with the
following dimensions: l 102 cm (40 in.), w 92 cm (36 in.), h 117 cm (46 in.). The container
and its contents weigh approximately 160 kg (350 lb). Other modules—such as the
computer, forepump, monitor, and options—are shipped in their own containers. Their
dimensions and weights are less than that of the container for the mass spectrometer.
The ETD module, forepump, and accessories are shipped in a container with the following
approximate dimensions: l 97 cm (38 in.), w 71 cm (28 in.), h 94 cm (37 in.). The container
and its contents weigh approximately 105 kg (230 lb).
Space and Load Requirements
The recommended layout for the LTQ XL/ETD system is shown in Figure 5 on page 13. The
space requirements and weights of the components of the typical ETD system are given in
Table 6 on page 14.
Place the LTQ XL/ETD and data systems on two adjacent workbenches. One workbench will
hold the LTQ XL/ETD system, the LC, the gas filter, and any other MS/LC options and must
have minimum dimensions of 1.0 × 1.53 m (3 × 5 ft). This workbench must also be capable
of supporting the weight of the LTQ XL/ETD system [141 kg (310 lbs)] plus the weight of
the liquid chromatograph and any other MS/LC options. Allow at least 92 cm (36 in.) of
vertical clearance between the top of the LTQ XL/ETD system and any shelves above it.
Free access to the rear of the LTQ XL/ETD system is required. The fully extended ion probe
handle extends 48 cm (19 in.) beyond the back panel of the LTQ XL/ETD system. The
minimum clearance between the wall and the fully extended ion probe handle on the back of
the ETD module must be 31 cm (12 in.); the recommended clearance is 46 cm (18 in.). The
minimum clearance from the back panel of LTQ XL/ETD system to the wall must be
79 cm (31 in.); the recommended clearance is 94 cm (37 in.).
In addition, LTQ XL/ETD system requires a reagent carrier source and a gas filter which will
require a small amount of space adjacent to gas tank. Refer to Figure 5 on page 13.
1Your instrument is shipped in a shipping container that is 92 cm (36 in.) at its narrowest. If the entrance to your
laboratory will not accommodate a 92 cm container, you can remove the individual modules from the container
before moving them into the room. If you remove the instrument from its shipping container before it is delivered
to the lab site, be sure that all the contents of the container remain with the instrument.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
11
2
Site Preparation
LTQ XL/ETD System
The system includes three forepumps: two large pumps for the MS detector and a smaller
pump for the ETD module. Install the forepumps on the floor close to the LTQ XL/ETD
system. The total length of the vacuum hose connecting the MS detector to the MS detector
forepumps (large pumps) should not exceed 2.43 m (8 ft) for each pump. The total length of
the vacuum hose connecting the ETD module to the ETD module forepump (small pump)
should not exceed 1.82 m (6 ft).
If the workbench has space beneath it, place the forepumps under the workbench
immediately behind the LTQ XL/ETD system. See the tabletop layout in Figure 5. Either run
the vacuum hose behind the workbench or make a 64 mm (2.5 in.) diameter hole through the
bench for the vacuum hose. Allow room to run the power cords from the forepumps through
the hole.
Table 6 on page 14 gives the approximate space and weight requirements of the various
components of the system.
12
LTQ Series Preinstallation Requirements Guide
Thermo Scientific
2
Figure 5.
Site Preparation
LTQ XL/ETD System
Workbench for an LTQ XL/ETD system
46 cm
(18 in.)
Free space
(absolute minimum)
Gas
filter
Surveyor LC
system
Ion volume tool
handle
Workbench
(top view)
ETD module
92 cm
(36 in.)
LTQ XL
mass spectrometer
Top
view
Front
view
152.5 cm
(60 in.)
LTQ XL mass spectrometer
with ETD module
Surveyor LC
system
Gas
filter
SURVEYOR
PDA Detector
Power
114 cm
(45 in.)
Comm
Run
Lamps
SURVEYOR
Autosampler
Power
Comm
Run
Data system
workbench
Temp
SURVEYOR
Wall outlet #3
for ETD module
230 V ac
Pump
Power
Comm
Run
Degas
Wall outlet #2
for mass spectrometer
230 V ac
Wall outlet #1
for Surveyor system (LC)
120 or 230 V ac
Thermo Scientific
Forepumps with
noise reduction covers
LTQ Series Preinstallation Requirements Guide
13
2
Site Preparation
LTQ XL/ETD System
Table 6. LTQ XL/ETD system space and load requirements
Height
Width
Depth
Weight
Module
cm
in.
cm
in.
cm
in.
kg
lb
LTQ XL/ETD system
(ion volume tool handle fully
extended)
56
22
79
31
109
43
141
310
Liquid chromatograph*
61
24
76
30
61
24
45
100
LTQ XL forepumps (each)
30
12
20
7
64
25
34
75
ETD module forepump
23
9
43
17
16
6
26
58
* Approximate.
The actual value depends on your equipment.
Note For your safety, Thermo Fisher Scientific recommends that the load rating for the
table where you place the LTQ XL/ETD system and LC unit be at least twice the weight
of the equipment placed on that table.
Electrical Requirements
CAUTION To prevent overloading the circuit, never connect the LTQ XL and the ETD
module to the same electrical wall outlet circuit.
The outlet power requirements in Table 7 are based on the LTQ XL/ETD system workbench
setup shown in Figure 5 on page 13.
Table 7. Power requirements for an LC and an LTQ XL/ETD system
Outlet #1
Liquid chromatograph*
Outlet #2
LTQ XL MS detector
Outlet #3
ETD module
120 V ac
10 A
N/A
N/A
230 V ac
5A
15 A
15 A
* Approximate.
14
LTQ Series Preinstallation Requirements Guide
The actual value depends on your equipment.
Thermo Scientific
2 Site Preparation
MALDI LTQ XL System
MALDI LTQ XL System
Entrance Requirements
The entrance to your facility and the width of all hallways, elevators, and so on must be a
minimum of 94 cm (37 in.).2 However, additional room must be allowed for maneuvering
the system around corners, into elevators, or through doorways.
The LTQ Series mass spectrometer and accessories are shipped in a container with the
following dimensions: l 102 cm (40 in.), w 92 cm (36 in.), h 117 cm (46 in.). The container
and its contents weigh approximately 160 kg (350 lb). Other modules—such as the
computer, forepump, monitor, and options—are shipped in their own containers. Their
dimensions and weights are less than that of the container for the mass spectrometer.
The MALDI LTQ XL system with the optics module and only the sample module cover with
its accessories is shipped in a container with the following dimensions: l 134 cm (53 in.),
w 91 cm (36 in.), h 124 cm (49 in.). The container and its contents weigh approximately
197 kg (435 lb).
The MALDI control module, XYZ mechanism, sample plates kit, and accessories are shipped
in a container with the following approximate dimensions: l 147 cm (58 in.),
w 88 cm (35 in.), h 119 cm (47 in.). The container and its contents weigh approximately
155 kg (342 lb).
Space and Load Requirements
For the MALDI LTQ XL system, use one workbench to hold the mass spectrometer and
separate movable benches for the MALDI control module and LC system if you plan to
switch between the MALDI and API sources. The movable bench for the LC system must
have the minimum dimensions of 1 × 0.9 m (3 × 3 ft) and be capable of supporting the
weight of the LC system. The movable bench for the MALDI control module must have the
minimum dimensions of 1 × 0.9 m (3 × 3 ft) and be capable of supporting the weight of the
control module.
2Your instrument is shipped in a shipping container that is 92 cm (36 in.) at its narrowest. If the entrance to your
laboratory will not accommodate a 92 cm container, you can remove the individual modules from the container
before moving them into the room. If you remove the instrument from its shipping container before it is delivered
to the lab site, be sure that all the contents of the container remain with the instrument.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
15
2
Site Preparation
MALDI LTQ XL System
CAUTION The conversion process between the MALDI and the Ion MAX™ API sources is
an installation task that must be performed by a Thermo Fisher Scientific field service
engineer or personnel with the appropriate training. If personnel without the appropriate
training attempt to convert a MALDI LTQ XL system to an LTQ XL API system,
instrument damage as well as personal injury can occur.
The MALDI LTQ XL system (P/N 97355-60500) does not contain an API source.
The API kit (P/N 97155-62123) contains the parts required to convert a MALDI
LTQ XL system to an LTQ XL API system.
The LTQ XL system with an API source uses two forepumps. Both forepumps connect to the
mass spectrometer. The MALDI LTQ XL system also uses two forepumps. One forepump
connects to the mass spectrometer and one forepump connects to the evacuated load lock
(lower) chamber inside the MALDI sample module.
See Table 8 for the space requirements and weights of a MALDI LTQ XL mass spectrometer
configured for the MALDI source or the Ion MAX API source. Figure 6 on page 17 shows the
LTQ XL mass spectrometer set up for MALDI mode. Figure 7 shows the LTQ XL mass
spectrometer set up for API mode.
Table 8. MALDI LTQ XL system space and load requirements
Height
Width
Depth
Weight
Module
cm
in.
cm
in.
cm
in.
kg
lb
MALDI LTQ XL
without the XYZ mechanism
56
22
99
39
59
23
197
435
MALDI control module
with grounding bracket
35
14
50
20
45
18
11
25
MALDI XYZ mechanism
(with brackets and connected
to its stand for maintenance)
53
21
60
24
53
21
27
60
Forepumps (each)
30
12
20
7
64
25
34
75
Note For your safety, Thermo Fisher Scientific recommends that the load rating for the
table where you place the MALDI LTQ/XL system be at least twice the weight of the
equipment placed on that table.
16
LTQ Series Preinstallation Requirements Guide
Thermo Scientific
2 Site Preparation
MALDI LTQ XL System
Figure 6.
MALDI LTQ XL system
30 cm
(12 in.)
MALDI
control
module
99 cm
(39 in.)
MALDI LTQ XL
mass spectrometer
17 - 35 cm
(7 - 14 in.)*
Data system
workbench
External vent for the
forepump exhaust
Forepumps with
noise reduction cover
Wall outlet #1
for mass spectrometer
230 V ac
* Distance is variable, depending on how the grounding bracket is installed.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
17
Figure 7.
Workbench for MALDI LTQ XL with API source and movable workbenches for optional LC system and MALDI control module
50 cm
(20 in.)
38 cm
(15 in.)
MALDI
control
module
99 cm
(39 in.)
Accela
LC system
LTQ XL
mass spectrometer
APDACCELA
Detector
PDA detector
Power
Communication
Run
Category 5,
shielded
Ethernet
cables
Lamps
Autosampler
AAutosampler
CCELA
Power
Communication
Run
Temperature
Power
Communication
Run
Degas
Accela pump
114 cm
(45 in.)
ACCELA
Pump
Data system
workbench
Wall outlet #1
for Accela LC system
120 or 230 V ac
Solvent
trap
External vent for the
solvent trap connected
to the API source
18
LTQ Series Preinstallation Requirements Guide
Forepumps with
noise reduction cover
Wall outlet #2
for mass spectrometer
230 V ac
External vent for the
forepump exhaust
Thermo Scientific
2
Site Preparation
Forepumps
Electrical Requirements
Note The MALDI source draws a current of 5.5 A from the mass spectrometer.
The outlet power requirements in Table 9 are based on the MALDI LTQ XL workbench
setup shown in Figure 6 on page 17.
Table 9. Power requirements for a MALDI LTQ XL system
Outlet #1
Liquid chromatograph*
Outlet #2
MALDI LTQ XL
120 V ac
10 A
N/A
230 V ac
5A
15 A
* Approximate.
The actual value depends on your equipment.
Forepumps
Depending on available space, you have two options for the placement of the forepump or
forepumps and for connecting the vacuum hose from the mass spectrometer to the
forepumps.
• If the workbench has space beneath it, place the forepumps under the workbench
immediately behind the LTQ Series mass spectrometer. Either run the vacuum hose
behind the workbench or make a 6.4 cm (2.5 in.) diameter hole through the bench for
the vacuum hose. Allow for room to run the power cords from the forepumps through the
hole. Figure 3 on page 8 shows the setup for the LXQ system that uses one forepump.
Figure 4 on page 9 shows the setup for an LTQ XL system that uses two forepumps.
Figure 5 on page 13 shows the setup for an LTQ XL/ETD system which uses three
forepumps, two for the LTQ XL and one for the ETD module. Figure 6 on page 17
shows the setup for a MALDI LTQ XL system using two forepumps.
• If the workbench has no space under or at the end of it, place the forepumps on the floor
in front of the LTQ Series mass spectrometer.
CAUTION Whenever possible, provide space under the workbench for the forepumps. If
placed in front of the mass spectrometer, the forepumps can block access to drawers and
cabinets and can represent a trip hazard.
IMPORTANT Do not place the forepumps on a shelf or other surface connected to the
table supporting the LTQ Series system. Vibration from the pumps can affect system
performance.
IMPORTANT To maintain forepump integrity, route the exhaust tubing from the exhaust
port down to the floor, not from the forepump vertically toward the ceiling.
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LTQ Series Preinstallation Requirements Guide
19
2
Site Preparation
Telephone
IMPORTANT The exhaust hose should travel at floor level for a minimum of two meters
(78.5 in.) before it reaches the external exhaust system. This tubing acts as a trap for
exhaust fumes that would otherwise recondense in the forepump oil.
Figure 8 shows the blue exhaust hose connected to the optional oil mist filter, which is
connected to the exhaust port of the forepump.
Figure 8.
Connecting the forepump exhaust to an external exhaust system
Vacuum port
Optional sound
control housing
EDWARDS
Forepump
Oil Mist Filter EMF 20
Optional
oil mist filter
Blue hose
(connect to external
exhaust system)
Note The forepump or forepumps plug into the power panel on the LTQ Series mass
spectrometer. The forepump for the ETD module, however, plugs into power panel of the
ETD module.
Telephone
Install a telephone in your laboratory near the instrument so that, if necessary, you can
conveniently operate the system while you are working by telephone with Thermo Fisher
Scientific Technical Support. Place the voice telephone outlet within 2 m (6 ft) of your
LC/MS system.
IMPORTANT Your instrument is designed to work in a controlled electromagnetic
environment. Do not use radio frequency transmitters, such as mobile phones, in close
proximity to the instrument.
20
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3
Operating Environment
Attention to the operating environment will ensure continued high performance of your
Thermo Scientific LC/MS system. Any expenditures for air conditioning are more than offset
by good sample throughput and reduced repair costs.
You are responsible for providing the operating environment necessary for proper operation of
the Thermo Scientific LC/MS system.
Contents
• Temperature
• Humidity
• Vibration
• Lighting
• Particulate Matter
• Electrostatic Discharge
Temperature
For precision instrumentation, such as the Thermo Scientific mass spectrometer, maintain the
laboratory room temperature between 15 and 27 °C (59 and 81 °F). For optimum
performance, maintain the room temperature between 18 and 21 °C (65 and 70 °F).
IMPORTANT As the laboratory temperature increases, system reliability decreases. All
electronic components generate heat while operating. This heat must be dissipated to the
surrounding air for the components to continue to operate reliably.
There must be a good flow of room air around the system, and the air conditioning system
must be capable of maintaining a constant temperature in the immediate vicinity of the
system.
IMPORTANT Do not place the mass spectrometer under an air duct, near windows, or
near heating and cooling sources. Temperature fluctuations of 5 °C or more over a
five-minute period of time can affect performance.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
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3
Operating Environment
Humidity
The air conditioning load for a basic LTQ Series mass spectrometer is approximately 2300 W
(8000 Btu/h). Refer to your LC manual for the heat output of your LC equipment.
Table 10 lists the approximate heat output of each module.
Table 10. Heat output
Module
Heat output
(in watts)
Mass spectrometer
2300
8000
Mass spectrometer with MALDI source
2650
9040
LTQ XL/ETD system
2300
8000
1060
3690
Monitor
240
820
Computer
470
1640
Laser printer*
350
1230
4420
15380
Liquid
chromatograph*
Total
* Approximate.
Heat output
(in Btu/h)
The actual values depend on your equipment.
Humidity
Maintain the relative humidity of the operating environment between 40 and 80 percent,
with no condensation.
Operating a Thermo Scientific mass spectrometer in an environment with very low humidity
can cause static electricity to accumulate and discharge, which can shorten the life of the
electronic components. Operating the system in an environment with high humidity can
cause condensation, oxidation, and short circuits. It can also cause dust to accumulate which
that can block filters on cooling fans.
To ensure that your laboratory is always within the required temperature and humidity
specifications, Thermo Fisher Scientific recommends that you equip your laboratory with a
temperature/humidity monitor.
Vibration
Keep floors free of vibration caused, for example, by equipment in adjoining locations.
Because of the natural vibration of the forepump or forepumps during operation, install the
forepump on the floor beneath the LTQ Series system and not near the system on the
workbench.
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3
Operating Environment
Lighting
Lighting
Good lighting makes any work area more enjoyable. Thermo Fisher Scientific recommends
that you use a small, high-intensity lamp when cleaning the mass spectrometer components.
Particulate Matter
Ensure that the air in your laboratory is free from excessive dust, smoke, or other
particulate matter in excess of 5 μm—that is, fewer than 3500000 particles per cubic meter
(100000 particles per cubic foot).
Dust can clog the air filters, causing reduced air flow around electronic components. Dust on
electronic components can act as an insulating blanket, which reduces the transfer of heat
from the components to the surrounding air.
Electrostatic Discharge
Electrostatic discharge (ESD) can damage the electronic components of your LTQ Series
system.
Most LTQ Series instruments are designed to withstand ESD up to 4 kV (air discharge) and
4 kV (contact discharge) with all panels in place. However, removing the panels and handling
the PCBs without proper precautions might damage the electrical components or cause them
to fail prematurely.
Static electricity can develop in a variety of ways. Some examples follow:
• Walking across a carpet in a room that is at 20 percent relative humidity can generate as
much as 35000 V of electrostatic potential on the surface of your body. A similar trip in a
room at 80 percent relative humidity generates about 1500 V of electrostatic potential.
• Sitting and working in a chair padded with polyurethane foam in a room at 20 percent
relative humidity can cause as much as 18000 V of electrostatic potential to develop on
your skin. At 80 percent relative humidity, the electrostatic potential can be as much as
1500 V.
• Working in laboratory coats and clothing made of synthetic fibers can cause static
electricity to accumulate on your skin.
• Using Styrofoam™ cups and packing materials results in a considerable electrostatic
charge.
The discharge of static electricity is not perceptible to humans until the potential is at least
4000 V. However, a discharge of electrostatic potential as small as 50 V can damage many
electronic components. While ESD damage can be catastrophic and cause your system to
cease functioning, more commonly, ESD damage might cause latent problems that are
detrimental to sensitive electrical components, causing premature failures.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
23
3
Operating Environment
Electrostatic Discharge
Because of ESD, Thermo Fisher Scientific recommends the following precautions, especially
when operating your system at the lower end of the relative humidity specification:
• Use a static-dissipating floor covering (such as tile or conductive linoleum) in the room
that houses your instrument.
• Use laboratory chairs covered with natural fibers or other static-dissipating material.
• Wear a laboratory coat and clothing made of natural fiber or other static-dissipating
material when you are operating the instrument.
• Keep Styrofoam cups or packing materials away from the instrument.
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4
Line Power
The quality of line power delivered to your system can affect its performance and longevity.
To ensure that your instrument performs optimally and is not damaged by line power
fluctuations, verify that your laboratory electrical supply complies with all power quality
requirements.
It is your responsibility as the user to provide a power source of acceptable quality to operate
your system.
Contents
• Quality of Power
• Power Monitoring Devices
• Power Conditioning Devices
• Available Outlets
• Connecting the Modules to Wall Outlets
• Uninterruptible Power Supply
• Technical Assistance
Quality of Power
The quality of power supplied to your LTQ Series system is very important. The line voltage
must be stable and within the specifications listed in this guide. The line voltage must be free
of fluctuations due to slow changes in the average voltage, surges, sags, or transients.
Table 11 contains definitions for the three most common voltage disturbances.
Thermo Scientific
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4
Line Power
Power Monitoring Devices
Table 11. Common voltage disturbances
Voltage disturbance
Definition
Slow average
A gradual, long-term change in average root mean square
(RMS) voltage level, with typical durations greater than 2 s
Sags and surges
Sudden changes in average RMS voltage level, with typical
durations between 50 μs and 2 s
Transients or impulses
Brief voltage excursions of up to several thousand volts with
durations up to 50 μs
Constant high line voltage, impulses, or surges in voltage can cause overheating and
component failures. Constant low line voltage or sags in voltage can cause the system to
function erratically or not at all. Transients, even a few microseconds in duration, can cause
electronic devices to fail catastrophically or degrade, eventually shortening the lifetime of your
system. For all of these reasons, it is important to establish the quality of the line voltage in
your laboratory before installing your LTQ Series system.
Power Monitoring Devices
Several devices are available to monitor the quality of your line power.
These devices provide a continuous record of line performance by analyzing and printing out
data on the three most common voltage disturbances: slow average, sag and surge, and
transient.
In the first two cases, the time interval recording indicates the duration and the amplitude of
the disturbance. A power line disturbance analyzer is a device capable of detecting and
recording most types of line power problems. The Dranetz™1 system is an example of a
suitable analyzer. You can rent power line analyzers from electrical equipment suppliers.
Monitor the power line 24 hours a day for seven consecutive days. If inspection of the
printout indicates disturbances, terminate the test and take corrective action. Monitor the
power again as previously described.
1Thermo
Fisher Scientific does not endorse any power monitoring company, nor does it endorse products other
than its own. Companies and products listed in this guide are given as examples only.
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4 Line Power
Power Conditioning Devices
Power Conditioning Devices
You can correct a line voltage problem using various line voltage conditioning devices. If you
have good regulation but the power line disturbance analyzer shows transient voltages, then an
isolation/noise-suppression transformer can resolve the problem. If there are both transient
and regulation problems, consider power conditioners that can control these problems.
CAUTION Any conditioning devices installed with your system must be able to deal with
the potentially high currents that are drawn during the initial startup of the system. For
example, during startup, the forepump can draw a high inrush current.
Inrush current is the initial current flowing through an inductive load, such as a motor,
when it is first turned on. Since Thermo Scientific MS systems require the use of one or
two mechanical vacuum pumps, they draw an inrush current. The maximum inrush
current for the mechanical vacuum pump is approximately 30 A at 230 V, with an average
duration of less than one second. (On average, the typical duration of the inrush current is
below 100 ms.) Therefore, this initial energy (watts-sec) demand for the 230 V ac line is
very low. Thermo Scientific MS systems are protected from an overcurrent with
time-delay fuses and active switches. Contact your Thermo Fisher Scientific field service
engineer for more information.
When the line voltage is free from voltage sags, surges, and impulses but is more than
10 percent outside of the voltage specifications, a buck/boost transformer can lower
(buck 10 percent) or raise (boost 10 percent) the line voltage.
IMPORTANT The nitrogen generator requires a buck/boost transformer if the line voltage
is outside of the 230 V ac, ±10% voltage specification.
Each buck/boost transformer is encased in a metal housing approximately 13 × 13 × 26 cm
(5 × 5 × 10 in.) and is equipped with a 2 m (6 ft) power cable. To order the buck/boost
transformer kit (P/N OPTON-01460), contact Thermo Fisher Scientific San Jose, and then
have your electrician install the buck/boost transformer before you start to install your system.
The installation instructions for the transformer are included.
CAUTION For compliance and safety, your uninterruptible power supply (UPS) devices
must be certified by recognized domestic and international organizations (for example,
UL, CSA, TÜV, and VDE).
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LTQ Series Preinstallation Requirements Guide
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4
Line Power
Available Outlets
Available Outlets
The LTQ Series mass spectrometer is designed to operate at a nominal voltage of 230 V ac,
50/60 Hz. Line voltages can vary between a minimum of 207 V ac and a maximum of
253 V ac.
CAUTION Systems installed in areas with 208 V power experience voltage sags during
high use periods that might place the line voltage below the operating parameters
discussed in this section. In this case, you must protect your instrument by using a
buck/boost transformer to ensure that power is within the specified parameters at all
times.
The minimum and maximum voltage tolerances are in compliance with EN60950-1:2001, as
follows:
“If the equipment is intended for direct connection to an AC mains supply, the tolerances
on rated voltage shall be taken as +6% and -10% unless the rated voltage is 230 V single
phase or 400 V three-phase, in which case the tolerance shall be taken as +10% and
-10%.”
For systems installed in regions with both 120 V ac and 230 V ac service, the basic power
requirements for an LTQ Series system consist of the following:
• Nominal voltage of 120 V ac, +6% to -10% and 230 V ac, ±10% and free from voltage
variations above or below this operating range
• Frequency of 50/60 Hz
• Two fourplex outlets (single-phase power) with a minimum power rating of 20 A
(120 V ac)
• One fourplex outlet (single-phase power) with a minimum power rating of 16 A
(230 V ac)
• 20 A option in the U.S., where only 15 and 20 A power rating options are available
• Earth ground hard-wired to the main panel
For systems installed in areas with 230 V ac only service, the basic power requirements for a
LTQ Series system consist of the following:
• Nominal voltage of 230 V ac, ±10%
• Frequency of 50/60 Hz
• Three fourplex outlets, with a minimum power rating of 16 A at each fourplex outlet
• Earth ground hardwired to the main panel
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4 Line Power
Available Outlets
IMPORTANT
1. Ensure that the LTQ Series system has an earth ground hardwired to the main panel.
The interconnected power outlets for the LTQ Series system are to have a common
point to one ground connector. If two points are connected to separate external
ground, they can cause noise current to flow through the ground system via the
ground loop that is formed.
2. Ensure that the power remains on. The LTQ Series system should remain on and
pump continuously for optimum performance.
3. Have additional power outlets available for test and cleaning equipment, such as an
oscilloscope and ultrasonic bath. Thermo Fisher Scientific recommends that there be
several additional power outlets close to the workbench space within your laboratory.
Chapter 2, “Site Preparation,” on page 3 contains illustrations and tables that define the
location and specifications for the power outlets for all LTQ Series systems.
The power cable from the LTQ Series mass spectrometer is 3 m (9 ft), and the cables from the
personal computer, monitor, and printer are approximately 2 m (6 ft) long.
IMPORTANT
The LTQ Series mass spectrometer is shipped with a NEMA 6-15P plug, rated at 15 A
and 250 V ac. The data system computer is shipped with a NEMA 5-15P plug, rated at
15 A and 125 V ac. The printer is shipped with either a NEMA 5-15P plug or with a
220 V ac European CEE 7/7 (Schuko) plug, as is the scanner in the MALDI tissue
imaging kit.
Local codes in your area might require the installation of another type of plug and
receptacle. The Thermo Fisher Scientific field service engineer for your country provides
the appropriate power plugs.
Figure 9 shows the NEMA plugs and their corresponding outlets.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
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4
Line Power
Available Outlets
Figure 9.
NEMA 6-15P and NEMA 5-15P power plugs and their respective outlets
NEMA 6-15P
Outlet
Plug
Outlet
Plug
NEMA 5-15P
Table 12 lists the maximum current that each component of a typical LTQ Series system
requires. The LTQ Series mass spectrometer operates with 230 V ac only. You can manually
set other components to 120 V ac or 230 V ac or order them with a 120 V ac or 230 V ac
option.
CAUTION The values listed in Table 12 are the average currents drawn by each of the
listed components. Any conditioning devices installed with your system must also handle
the potentially high currents drawn during the initial startup of the system. For example,
during startup, the forepump can draw a high inrush current.
Inrush current is the initial current flowing through an inductive load, such as a motor,
when it is first turned on. Because Thermo Scientific MS systems require the use of one or
two mechanical vacuum pumps, they draw an inrush current. The maximum inrush
current for the mechanical vacuum pump is approximately 20 A, with a maximum
duration of less than one second. (The typical duration of the inrush current is below
100 ms.) Time-delay fuses and active switches protect Thermo Scientific MS systems
from an overcurrent. Contact your Thermo Fisher Scientific field service engineer for
more information.
For more details on the surge requirements for your system, consult the forepump manual
or your Thermo Fisher Scientific field service engineer.
Table 12. Maximum current (single phase) drawn (Sheet 1 of 2)
Module
LTQ Series MS detector
(230 V only)
(not including the forepump)
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LTQ Series Preinstallation Requirements Guide
Voltage 120 V ac current
(in amperes)
Voltage 230 V ac current
(in amperes)
N/A
3 to 5 (5 A inrush)
(10 A inrush with the
ETD module)
Thermo Scientific
4 Line Power
Available Outlets
Table 12. Maximum current (single phase) drawn (Sheet 2 of 2)
Module
Voltage 120 V ac current
(in amperes)
Voltage 230 V ac current
(in amperes)
Forepumps
N/A
5 (20 A inrush)
(30 A inrush with the
ETD module)
Liquid chromatograph
10
5
Monitor
2
1
4
2
Laser printer
3
2
Scanner
(in the MALDI tissue imaging kit)
3
2
Computer
*
* Approximate.
The actual value depends on your equipment.
Note Refer to your LC equipment manual for power requirements and specifications.
Installing a complete LC/MS system can require extensive electrical resources. Plan the power
system properly, with numerous outlets, to ensure that you can connect and power all of your
equipment. See the sample laboratory setup in Table 13 for the recommended number of
outlets.
Table 13. A sample laboratory setup (Sheet 1 of 2)
LC system
MS system
Thermo Scientific
Item
Outlets
Autosampler
1
LC pump
1
UV/Vis or PDA detector (optional)
1
Column heater (optional)
1
External controller (optional)
1
Mass spectrometer
1 (230V)
MALDI source plugs into the mass spectrometer
N/A
API source plugs into the mass spectrometer
N/A
Forepumps plug into the mass spectrometer
N/A
ETD module
1 (230V)
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4
Line Power
Connecting the Modules to Wall Outlets
Table 13. A sample laboratory setup (Sheet 2 of 2)
Data system
Optional
Item
Outlets
Computer
1
Monitor
1
Printer
1
Scanner (in the MALDI tissue imaging kit)
1
Ethernet switch
1
High-intensity lamp (for help in instrument maintenance)
1
Laboratory stereoscope (for inspecting fused-silica parts)
1
Total outlets required for this configuration
7 to 14
Connecting the Modules to Wall Outlets
Take care not to exceed the wall outlet specifications. The maximum load for a 120 V ac
fourplex outlet is typically 20 A, and the maximum load for a 230 V ac fourplex outlet is
typically 16 A. See Table 12 for the maximum current ratings for the LTQ Series system and
the data system.
To prevent overloading the circuit, connect the mass spectrometer, liquid chromatograph, and
data system to separate wall outlets. For an LTQ XL/ETD system, connect the ETD module
to a fourth 230 V ac wall outlet. The LTQ Series mass spectrometer operates with 230 V ac
only. You can manually set other components to 120 V ac or 230 V ac or order them with a
120 V ac or 230 V ac option.
See the workbench setup illustrations in Chapter 2, “Site Preparation,” on page 3 for more
information about the wall outlet requirements for each setup.
Uninterruptible Power Supply
If your local area is susceptible to corrupted power or power disruptions, install an
uninterruptible power supply (UPS) in your laboratory.
CAUTION For compliance and safety, your uninterruptible power supply (UPS) devices
must be certified by recognized domestic and international organizations (for example,
UL, CSA, TÜV, and VDE).
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4 Line Power
Technical Assistance
Technical Assistance
Occasionally, you might encounter line power sources of unacceptable quality that adversely
affect the operation of an LTQ Series system. You are responsible for correcting line power
problems. Contact your Thermo Fisher Scientific office for assistance in monitoring the line
voltage in your laboratory and in selecting a line conditioner.
Specifying power conditioning equipment is a complex task that is best handled by a company
or consultant specializing in that field. Contact your Thermo Fisher Scientific office for
assistance in locating a power consultant in your area.
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LTQ Series Preinstallation Requirements Guide
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5
Gases and Solvents
The LTQ Series mass spectrometers require high-purity gases and solvents for daily operation.
The Thermo Fisher Scientific field service engineer might also require certain solvents for the
installation verification of your system.
Note You are responsible for providing the correct gas and solvent supplies necessary for
the operation of the system.
Contents
• Fittings and Parts
• Gases
• Solvent Recommendations
Fittings and Parts
Table 14 lists the minimum parts that are required to connect your LTQ Series system to your
gas delivery system. Connections and gas delivery systems might vary. You are responsible for
supplying any fittings or connections necessary during installation.
The following kits that are shipped with the LTQ Series system contain the tubing and fittings
listed in Table 14.
• MS Ship Kit (P/N 70111-62033)
• MS Accessory Kit (P/N 70111-62034)
• Special Accessory Kit for the LXQ (P/N 97055-62045)
• Special Accessory Kit for the LTQ XL (P/N 97055-62044)
• ETD Accessory Kit (P/N 98000-62002) containing the reagent carrier gas filter and
other parts in addition to the items listed in Table 14
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5
Gases and Solvents
Fittings and Parts
Table 14. Gas connection hardware requirements
Gas type
Description
Part number
Nitrogen
Two 6 ft lengths of 1/4 in. OD Teflon™
PFA hose are provided. Your installation
might require an additional length of
tubing.
00101-50100
Brass Swagelok™ 1/4 in. ID nut
00101-12500
2-piece brass 1/4 in. ID ferrule set
00101-10000 (front)
00101-04000 (back)
Connection for the opposite end of the
Teflon hose to the nitrogen gas source.
Not provided
Two 6 ft lengths of 1/8 in. OD pre-cleaned
copper tubing are provided. Your
installation might require an additional
length of tubing.
00301-22701
Brass Swagelok 1/8 in. ID nut
00101-15500
2-piece brass 1/8 in. ID ferrule set
00101-08500 (front)
00101-02500 (back)
Connection for the opposite end of the
tubing to the helium gas source.
Not provided
One 10 ft length of 1/8 in. OD pre-cleaned
copper tubing is provided. Your installation
might require an additional length of
tubing.
00301-22701
Brass Swagelok 1/8 in. ID nut
00101-15500
2-piece brass 1/8 in. ID ferrule set
00101-08500 (front)
00101-02500 (back)
Stainless steel Swagelok 1/8 in. ID nut
00101-07-00004
2-piece stainless steel 1/8 in. ID ferrule set
00101-08-00009
Connection for the opposite end of the
tubing to the reagent carrier gas source.
Not provided
Helium
ETD reagent
carrier gas
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5
Gases and Solvents
Gases
Gases
The LTQ Series mass spectrometer uses helium as the damping gas and nitrogen as the API
sheath gas and the auxiliary/sweep gas. The MALDI LTQ XL system uses nitrogen gas to
maintain the pressure in the upper sample chamber of the MALDI source at 75 mTorr.
The gas connections are located on the back panel of the mass spectrometer as shown in
Figure 10.
Figure 10. Gas connections on the back panel of an LTQ Series mass spectrometer
Nitrogen In
690±140 kPa
(100±20 psi)
Helium In
275±75 kPa
(40±10 psi)
On an LTQ XL/ETD system, the gas lines connect to the back of the ETD module
(Figure 11). The ETD module also has an additional connector for a reagent carrier gas source
as described in “ETD Reagent Carrier Gas” on page 40.
Thermo Scientific
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5
Gases and Solvents
Gases
Figure 11. Gas connections on the rear panel of the ETD module
ETD reagent
carrier gas
690±140 kPa
(100±20 psi)
99.9999% pure
< 1 ppm H2O
< 1 ppm O2
Nitrogen In
690±140 kPa
(100±20 psi)
Helium In
275±75 kPa
(40±10 psi)
Your LTQ Series mass spectrometer can use large amounts of gases during daily operations.
Ensure that the gases are delivered with the necessary pressure and purity. See the following
topics for information on the purity and pressure that your system requires:
• “Helium,” next section
• “Nitrogen” on page 39
• “ETD Reagent Carrier Gas” on page 40
CAUTION Contaminants introduced during the installation of house lines used for gas
delivery can cause damage to the system. Ensure that all gas lines used with your system
have been cleaned of all particulates and oils. You are responsible for any damage to the
instrument caused by contaminants introduced from your gas delivery system.
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5
Gases and Solvents
Gases
Helium
The LTQ Series mass spectrometers use helium as the damping gas.
The helium supply must be ultra high-purity (minimum purity, 99.995%; recommended
purity, 99.999%) with less than 1.0 ppm each of water, oxygen, and total hydrocarbons. The
required gas pressure is 275 ± 35 kPa (40 ±5 psi). Because particulate filters can be a source of
contamination, Thermo Fisher Scientific does not recommend their use.
To dispense helium from a tank (such as one containing 245 t3 of helium), use a regulator
suitable for helium1.
Use copper or stainless steel gas lines for helium. Make sure that the gas lines are free of oil
and preferably flame dried. The gas line must run to the back of the LTQ Series mass
spectrometer, except when an ETD module is used where the gas line should run to the back
of the ETD module. The helium gas supply line must terminate with 1/8 in., female,
Swagelok-type connector.
Note
1. Do not shut off the helium gas. Optimum performance of the LTQ Series mass
spectrometer requires a continuous flow of helium.
2. If you intend to use helium for sparging your LC solvents, you must have a second
tank and regulator.
Nitrogen
The LTQ Series mass spectrometers use nitrogen as the API sheath gas and the
auxiliary/sweep gas. The MALDI LTQ XL system uses nitrogen gas to maintain the pressure
in the upper sample chamber of the MALDI source at 75 mTorr. The nitrogen supply must
be high-purity (99%). The required gas pressure is 690 ± 140 kPa (100 ± 20 psi).
Note You must provide a regulator for the nitrogen supply that is adjustable over the
specified pressure range.
Run the nitrogen gas line to the back of the LTQ Series mass spectrometer, except when an
ETD module is connected, in which case you must run the line to the back of the ETD
module. Terminate the nitrogen gas supply line with a 1/4 in., female, Swagelok-type
connector. Because particulate filters can be a source of contamination, Thermo Fisher
Scientific does not recommend their use.
1For
Thermo Scientific
more information visit http://www.matheson-trigas.com or consult a regulator supplier of your choice.
LTQ Series Preinstallation Requirements Guide
39
5
Gases and Solvents
Gases
With typical nitrogen gas consumption (when nitrogen is on 24 hours per day) at 5560 L
(200 ft3) per day, up to 26700 L (960 ft3) maximum usage per day, Thermo Fisher Scientific
recommends one of the following sources for your nitrogen supply:
• A large, sealed, thermally insulated cylinder containing liquid nitrogen from which the
nitrogen gas is boiled off. Because the 35 psi (240 kPa) and 80 psi (550 kPa) models do
not provide sufficient gas pressure, Thermo Fisher Scientific recommends a 230 psi
(1590 kPa) model. A typical 240 L cylinder yields 143850 L (5080 ft3) of gas. Replace
the cylinder approximately once every month.
• A nitrogen generator with a minimum capacity of 5560 L (200 ft3) per day at 99% purity
with 100 psi (689 kPa) at the side panel. Maximum consumption of nitrogen gas is
21 L/min (40 ft3/h). Nitrogen generators require an air compressor. Because some models
of air compressors are quite noisy, be careful to select a quiet compressor. A generator is a
continuous source, with no replacement required. A nitrogen generator does not produce
nitrogen of a sufficient purity to be used with the ETD module.
Note Liquid nitrogen conversion factors:
• 1.0 lb of liquid nitrogen = 0.5612 L
• 1.0 kg of liquid nitrogen = 1.237 L
Note When you turn on the LTQ Series system, the initial nitrogen surge might exceed
the capacity of the nitrogen generator. This sudden surge causes a flow rate drop that can
trigger a low nitrogen warning from the LTQ Series system. If low nitrogen warnings
happen frequently, call your Thermo Fisher Scientific field service engineer.
ETD Reagent Carrier Gas
The ETD module requires an additional ultra high-purity reagent carrier gas that is connected
to the triple (oxygen/water/hydrogen) gas filter supplied in the ETD Accessory Kit
(P/N 98000-62002) and then to the rear of the ETD module as shown in the LTQ Series
Getting Connected Guide.
Thermo Fisher Scientific strongly recommends a mixture of 25% helium and 75% nitrogen
This gas mixture must be ultra high-purity (minimum purity 99.999%) with less than 3.0
ppm each of water, oxygen, and total hydrocarbons. The required gas pressure is 275 ± 35 kPa
(100 ±20 psi). This mixture is available in the United States from Airgas, part number
X02NI75C200F464. The ETD module consumes less than 1 ATM cc/m of reagent carrier
gas, so a standard large bottle (245 ft3) of gas lasts approximately two years.
The helium in this mixture serves as a tracer gas to enable leak checking of gas connections
using conventional thermal conductivity-based leak detectors, which are widely used to check
leaks in gas chromatography equipment.
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5 Gases and Solvents
Solvent Recommendations
If the helium/nitrogen mixture is not available, then use a nitrogen supply that is ultra
high-purity (99.999%) with less than 3.0 ppm each of water, oxygen, and total hydrocarbons.
The required gas pressure is 275 ± 35 kPa (100 ±20 psi).
Note A nitrogen generator does not produce nitrogen of a sufficient purity to be used as
the ETD reagent carrier gas.
The triple gas filter, when installed between the regulator on the gas source and the ETD
module, further ensures that the reagent carrier gas (either nitrogen or helium/nitrogen) is
better than 99.999% pure with much less than 1 ppm of oxygen, water, and hydrocarbons.
Refer to the filter manufacturer’s instructions for information about how to monitor the color
changes in the filters that indicate when the filters need to be replaced, as well as information
about where to order new filters. If there are no leaks in the reagent carrier gas plumbing, you
can expect the filters to last a year or more. Thermo Fisher Scientific strongly recommends
that a Thermo Fisher Scientific field service engineer replace the gas filters.
You must provide a regulator for either gas supply that is suitable for such ultra high-purity
grade gas. Generally, a two-stage regulator with a machined brass body and an elastomer-free
metal diaphragm is adequate. The regulator should be able to stably output the specified
nominal pressure of 100 (±20) psig (relative to atmosphere) and have a 1/8 in. Swagelok-type
compression fitting output connection. Your gas supplier should be able to recommend a
suitable regulator that connects to the high pressure connection on their gas bottles. The ETD
Accessory Kit contains pre-cleaned copper tubing to connect this carrier gas supply to the gas
filter and the gas filter to the rear of the ETD module. If your installation requires more
copper tubing than is supplied in the kit, use only GC-cleaned copper tubing or flame dried
stainless steel tubing.
Note Do not shut off the reagent carrier gas. Optimum performance of the LTQ Series
mass spectrometer requires a continuous flow of reagent carrier gas.
Solvent Recommendations
As specified in Table 15, use only HPLC-grade solvents and reagents for operating and
maintaining your LTQ Series system. Installing of the LTQ Series system requires
HPLC-grade methanol and water. Installing of some systems might also require solvent
modifiers.
Note Some solvent impurities are transparent to UV/Vis detectors. Therefore, some
HPLC-grade solvents might contain contaminants that interfere with the performance of
the mass spectrometer. To operate your LTQ Series system, choose high-purity solvents
with minimum contamination. Thermo Fisher Scientific recommends solvents from the
following manufacturers: Merck, Mallinckrodt, and Burdick & Jackson.
Thermo Scientific
LTQ Series Preinstallation Requirements Guide
41
5
Gases and Solvents
Solvent Recommendations
Table 15. Recommended solvents and reagents
Solvent / Reagent
Specifications
Methanol
HPLC grade
Acetonitrile
HPLC grade
Water
HPLC grade
Isopropyl alcohol
HPLC grade
Acetic acid (modifier)
HPLC grade
Formic acid (modifier)
99-100% (It is required that this acid be supplied in a
glass bottle.)
Note Do not filter solvents. Filtering solvents can introduce contamination.
Store and handle all chemicals in accordance with standard safety procedures.
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6
Waste and Exhaust
The waste and exhaust arrangements for the instrument can affect the proper performance of
your system. Vacuum and solvent wastes must be vented separately, and wastes must be
collected and disposed of properly.
It is your responsibility to provide the proper waste and exhaust systems that are required to
operate the system.
Contents
• Exhaust System
• Solvent Waste
Exhaust System
Thermo Fisher Scientific strongly recommends connecting the forepumps to a fume exhaust
system. The forepumps eventually exhaust much of what is introduced into the LTQ Series
mass spectrometer, including the small amount of oil vapor that mechanical pumps can emit.
It is your responsibility to provide an adequate exhaust system.
Note The proper operation of the forepumps requires an efficient fume exhaust system.
Most atmospheric pressure ionization (API) applications contribute to the accumulation
of solvents in the forepumps. While Thermo Fisher Scientific recommends that you
periodically open the ballast valves (on the top of the pumps) to purge the accumulated
solvents, opening the valves might allow a large volume of volatile solvent waste to enter
the fume exhaust system. Choose an exhaust system that can accommodate the periodic
purging of these solvents. The frequency of the purging depends on the throughput of
your system.
The forepump (also referred to as a mechanical, rotary-vane, roughing, or backing pump)
provides a vacuum for the capillary skimmer of the API source, backing pressure for the
turbomolecular pump in the LTQ system, and backing pressure for the turbomolecular
pumps in the ETD module.
Thermo Scientific
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6
Waste and Exhaust
Solvent Waste
CAUTION The forepump waste line must not have a vertical run near the forepump.
Solvents and oils can condense in this line. A waste line vertical run near the forepump
could allow condensed vapors to flow back into the pump. This will cause the loss of
pump capability and damage to the pump.
The forepumps require one 25 mm (1 in.) OD exhaust port. For an LTQ XL system, which
uses two forepumps, you can Tee the blue exhaust hosing from each forepump into a third
section of hosing, and connect the third section of hosing to the external exhaust system. See
Figure 4 on page 9. The exhaust system for the forepumps must be able to accommodate an
initial inrush flow rate of 3 L/min and a continuous flow rate of 1 L/min.
Solvent Waste
Because the Ion Max API source can accommodate high flow rates, you must collect the waste
solvent in a manner that avoids pressure buildup in the source. The Ion Max API source is
fitted with a 25.4 mm (1.0 in.) OD outlet for solvent drainage. A 25.4 mm to 12.7 mm (1 in.
to 0.5 in.) reducing fitting (P/N 00101-03-00001) connects to a waste container
(P/N 00301-57020), both of which come with the system. To avoid pressure buildup in the
source, make sure that the 1-inch diameter hose from the API source drain to the reducing
fitting (P/N 00101-03-00001) is as long as possible. The 25.4 mm (1 in.) diameter Tygon™
PVC tubing (P/N 00301-22922) that comes with the system is 1.52 m (5 ft) long.
CAUTION Do not vent the PVC drain tubing (or any vent tubing connected to the waste
container) to the same fume exhaust system that the forepump is connected to.
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7
Installation
Prior to installation, make sure to complete all preparations described in the previous
chapters.
Note If the instrument shipping container, Shock Watch, or other indicators show any
evidence of damage or mishandling during shipment, do NOT open the container. Call
your Thermo Fisher Scientific representative for instructions on what to do. If the system
arrives safely, proceed with the following instructions.
After you have completed your laboratory site preparation, mailed or faxed the LTQ Series
Installation Request (at the front of this guide) to your local office for Thermo Scientific San
Jose products, and received the system, call your Thermo Fisher Scientific office to set an
installation date. Telephone and fax numbers for Thermo Fisher Scientific San Jose offices are
listed in the Preface of this guide and immediately follow the LTQ Series Installation Request.
Contents
• Installation Kits
• Fluoranthene for the LTQ XL/ETD System
• MALDI LTQ XL System Kits
• Installation
• MALDI-Specific Equipment, Consumables, and Solvents
Thermo Scientific
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7
Installation
Installation Kits
Installation Kits
The following kits are shipped with all LTQ Series systems:
Note You are responsible for replacing any consumables used during the installation.
• MS Ship Kit (P/N 70111-62033), which contains installation components, such as the
exhaust and waste tubing and power cords.
• MS Accessory Kit (P/N 70111-62034), which contains parts such as fuses, fittings,
tubing, and tools.
• Standard Chemicals Kit (P/N 97000-62042), which contains the necessary chemicals for
demonstrating system performance specifications. The Chemicals Kit is located in the
Accessory Kit box.
Other kits are shipped with specific system types, as described in the following sections.
LXQ Accessory Kit
Special Accessory Kit for the LXQ/LCQ Fleet (P/N 97055-62045), which contains parts such
as fuses, fittings, tubing, and tools; a chemical kit; and the LXQ/LCQ Fleet ion transfer tube
and other items.
LTQ XL Accessory Kit
Special Accessory Kit for the LTQ XL (P/N 97055-62044), which contains parts such as
fuses, fittings, tubing, and tools; a chemical kit; and the LTQ/LTQ XL ion transfer tube and
other items.
LTQ XL/ETD System Kits
The following kits are shipped with the LTQ XL/ETD system:
• ETD Accessory Kit (P/N 98000-62002), which contains filaments and other items as
well as the gas filter kit, pre-cleaned copper tubing, and fittings to connect it to the ETD
module and the reagent carrier gas supply.
• ETD Ship Kit (P/N 98000-62004).
• ETD Reagent Kit (P/N 98000-62008) which contains one vial each of fluoranthene and
Angiotensin I.
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7 Installation
MALDI LTQ XL System Kits
Fluoranthene for the LTQ XL/ETD System
Fluoranthene is used as the electron transfer dissociation (ETD) reagent in the ETD module
portion of the LTQ XL/ETD systems. The fluoranthene radical anion is generated according
to the reaction shown in Figure 12.
Figure 12. ETD reagent (fluoranthene radical anion) generation from fluoranthene
-•
+e→
Fluoranthene
Fluoranthene is potentially hazardous. Use it in accordance with its Material Safety Data
Sheet (MSDS).
CAUTION Store and handle all chemicals in accordance with standard safety procedures.
The Material Safety Data Sheet (MSDS) describing the chemicals being used are to be
freely available to lab personnel for them to examine at any time. Material Safety Data
Sheets (MSDSs) provide summarized information on the hazard and toxicity of specific
chemical compounds. MSDSs also provide information on the proper handling of
compounds, first aid for accidental exposure, and procedures for cleaning spills or dealing
with leaks. Producers and suppliers of chemical compounds are required by law to provide
their customers with the most current health and safety information in the form of an
MSDS. Read the MSDS for each chemical you use. Dispose of all laboratory reagents in
the appropriate way (see the MSDS).
The fluoranthene vial in your LTQ XL/ETD system Reagent Kit is Sigma-Aldrich Supelco™
#48535. To obtain another fluoranthene vial, click the MSDS link:
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SUPELCO/48535
MALDI LTQ XL System Kits
Two groups of kits are available for the MALDI LTQ XL system:
• “Required Chemical and Accessory Kits,” next section
• “Optional Accessory Kits” on page 48
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7
Installation
MALDI LTQ XL System Kits
Required Chemical and Accessory Kits
The required chemical and accessory kits are the following:
• ProteoMass™ MALDI Calibration kit available from Thermo Scientific
(P/N HAZMAT-01-0033) or Sigma-Aldrich (P/N MSCAL4, call 1-800-325-5832).This
kit contains the necessary chemicals to tune and calibrate the LTQ XL mass spectrometer
in the MALDI mode. The kit must be refrigerated at between 2 and 8 °C immediately
upon arrival at the location where the MALDI LTQ XL system is to be installed.
• MALDI Accessory Kit for the MALDI LTQ XL system (P/N 97155-62025), which
contains laser protective eye wear, tools, swabs, gloves, and other items and is shipped
with the MALDI LTQ XL system.
Optional Accessory Kits
The following are optional accessory kits for the MALDI LTQ XL system:
• Tissue Imaging Kit (P/N 97155-62124), containing tissue imaging slides, a software CD,
an adapter for stainless steel slides, an adapter for glass slides, a base plate, a scanner, and a
frame to hold the sample plate for scanning on the scanner.
• Sample Plate Kit (P/N 97155-62033), which contains a 96- and 384-well sample plate
and a base plate.
• API kit (P/N 97155-62123), which contains the parts required to convert a MALDI
LTQ XL system to an LTQ XL API system.
MALDI-Specific Equipment, Consumables, and Solvents
Operating the MALDI LTQ XL system requires this additional equipment:
• Sonicator bath large enough to hold a 1 L beaker
• Microcentrifuge
• Vortexer
• Pipettors (2.5 μL, 200 μL, and 1000 μL recommended; additional sizes might be useful)
• Analytical balance
Operating the MALDI LTQ XL system requires these additional consumables:
• Microcentrifuge tubes (500 μL)
• Tips for pipettors
• Optical lens wipes or soft clean room wipes
• Can of compressed difluoroenthane (sold as “compressed air” for dust removal)
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7
Installation
Installation
Operating the MALDI LTQ XL system requires these additional chemicals, as described in
the MALDI Source Getting Started Guide:
• Water
• Isopropyl alcohol
• Methanol
• Acetonitrile
• Acetone
• Trifluoroacetic acid (TFA)
• 20 to 30% ammonium hydroxide solution
Installation
When your new LTQ Series system is on site and ready for installation, a Thermo Fisher
Scientific field service engineer installs it.
During the installation, the field engineer demonstrates the following:
• The basics of equipment operation and routine maintenance.
• The marketing specifications that are in effect when you purchased the system.
Note To receive maximum benefit from this on-site training opportunity, plan for the
instrument operator to be available during the entire installation process.
Do not use your new system for sample analysis until the installation is complete and you
have signed the Acceptance Form.
Preventive Maintenance
You are responsible for the routine and preventive maintenance of your LTQ Series system
and data system computer.
Regular preventive maintenance is essential. It increases the life of the system, maximizes the
uptime of your system, and provides optimum system performance. Maintenance procedures
are covered in the following manuals:
• LTQ XL Hardware Manual
• LXQ Hardware Manual
• ETD Module Hardware Manual
• MALDI Source Hardware Manual
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8
Instrument Shipments
Electronic equipment carriers that specialize in the handling of delicate machinery ship the
LTQ Series system to your site. However, occasionally equipment is damaged in transit.
Take the following precautions when receiving instruments, supplies, or material:
• Check carefully for obvious damage or evidence of rough handling.
• Note any apparent external damage on all copies of the receiving documents and describe
briefly the extent of the damage. Have the driver sign (or initial) next to your comments
to signify agreement with your observations.
• To report the damage, contact the Traffic Department, telephone [1] (408) 965-6000, at
the Thermo Fisher Scientific office in San Jose, California, U.S.
Note Freight insurance requires that you record an obvious damage on the receiving
documents.
For domestic shipments, instruments are shipped by one of the following methods:
• FOB (freight on board) San Jose, California, U.S.
• FOB destination
If the system is damaged in transit, the method of shipment determines who has responsibility
for filing a claim against the carrier. If the instrument shipping container, Shock Watch, or
other indicators show any evidence of damage or mishandling during shipment, do NOT
open the container. Call your Thermo Fisher Scientific representative for further instructions.
Most systems are shipped FOB San Jose, and any damage incurred in shipment is the
responsibility of the purchaser and the carrier. However, Thermo Fisher Scientific San Jose
will assist with claims filing and (billable) repairs if necessary.
If the system is shipped FOB destination and is damaged, Thermo Fisher Scientific San Jose
files a claim against the carrier.
Note For domestic shipments, Thermo Fisher Scientific San Jose does not accept liability
for damage if materials are received with obvious damage AND the damage is not
recorded on the receiving documents.
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8
Instrument Shipments
When your system arrives, move it to a protected location indoors. If you have questions
about moving your system, contact your local office for Thermo Scientific San Jose products.
Telephone and fax numbers for the offices are listed in the Preface of this guide.
For international shipments, instruments (outside of the U.S.) are shipped carriage and
insurance paid (CIP) to the destination unless specified differently. If the system is shipped
CIP destination and if any damages are incurred in shipment, Thermo Fisher Scientific San
Jose files a claim against the carrier.
Note For international shipments, Thermo Fisher Scientific San Jose does not accept
liability for damage if materials are received with obvious damage AND the damage is not
recorded on the receiving documents.
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I
Index
A
acetonitrile 42
API kit 16, 48
B
ESD requirements 23
ETD module, nitrogen requirements 39
ETD reagent carrier gas
fittings 36
requirements 40
exhaust system 43
buck/boost transformer kit 27
F
C
chemicals needed for MALDI 47
claims, equipment damage 51
computer
current requirements 31
heat output 22
contaminants, gas, instrument damage 38
current, maximum 30
fans 22
floors, vibration 22
fluoranthene 47
forepump
exhaust plumbing 19
exhaust requirements 43
space requirements 19
freight insurance 51
D
G
damage during shipping 51
damaged equipment, claims 51
data system and scanner workbench 5
gas delivery systems fittings 35
gas regulator, specifications 39
gases
helium 39
nitrogen 39
E
electrical outlets, requirements 28
electrical requirements
LTQ XL 10
LTQ XL/ETD system 14
LXQ 10
MALDI LTQ XL system 19
electrostatic discharge requirements 23
EMC compliance 4
entrance requirements
LTQ Velos/ETD system 11
LTQ XL 7
LTQ XL/ETD system 11
LXQ 7
MALDI LTQ XL system 15
equipment needed for MALDI 47
Thermo Scientific
H
heat output 22
helium gas, requirements 39
humidity 22
I
installation kits 46
instrument damage
gas contaminants 38
solvent contaminants 41
insurance, freight 51
isolation/noise-suppression transformer 27
LTQ Series Preinstallation Requirements Guide
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Index: K
K
reliability, effect of temperature on system 21
kits 46
L
lighting requirements 23
line power
monitoring 26
requirements 25
liquid chromatograph voltage and current requirements 31
liquid nitrogen
conversion factors 40
specifications 39
load requirements
LTQ XL 7
LTQ XL/ETD system 11
LXQ 7
MALDI LTQ XL system 15
M
safety standards iii
sample plate kit 48
scanner 5
shipping damage 51
site preparation 3
solvents
acetonitrile 42
contamination, instrument damage 41
methanol 42
recommendations 42
waste from 44
space requirements
LTQ XL 7
LTQ XL/ETD system 11
LXQ 7
MALDI LTQ XL system 15
MALDI
API kit 48
chemical and accessory kits 47
tissue imaging kit 48
mass spectrometer, power 30
methanol 42
T
O
U
operating environment
electrostatic discharge 23
humidity 22
particulate matter 23
uninterruptible power supply 32
P
particulate matter requirements 23
plugs 29
power
monitoring devices 26
plugs, international, NEMA 29
quality of 25
preventive maintenance 49
ProteoMass calibration kit 48
R
reagent carrier gas for ETD
fittings 36
requirements 40
reagents 41
regulatory compliance iii
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LTQ Series Preinstallation Requirements Guide
telephone 20
temperature requirements 21
tissue imaging kit 48
trip hazards 19
V
vibration, floors 22
voltage spikes 28
voltages
allowed operating range 28
requirements for 230V supply 28
W
water, purity requirements 42
workbench
data system 5
data system with scanner 5
LTQ XL 9
LXQ 8
MALDI LTQ XL 17
Thermo Scientific