Cathepsin A Recombinant Protein
CATALOG NUMBER: 92-321
Specifications
SPECIES:
Human
SOURCE SPECIES:
Human Cells
SEQUENCE:
Ala29-Tyr480
FUSION TAG:
C-6 His tag
TESTED APPLICATIONS:
APPLICATIONS:
This recombinant protein can be used for biological assays. For research use only.
Properties
PURITY:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR
52.2 kD
WEIGHT:
PHYSICAL STATE:
Liquid
BUFFER:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to
a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
STORAGE CONDITIONS:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Additional Info
ALTERNATE NAMES:
Lysosomal protective protein, CTSA, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A
ACCESSION NO.:
P10619
Background
Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when
they are no longer needed. Cathepsin A interacts with the enzymes beta -galactosidase and neuraminidase 1, which play a role in the breakdown of
complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex
with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and
prevents their breakdown.
FOR RESEARCH USE ONLY
December 14, 2016