ÄKTA™ instrument
ÄKTA avant
ÄKTA pure
ÄKTAmicro
ÄKTAxpress
Site Preparation Guide
Table of Contents
Table of Contents
1
Introduction ..........................................................................................................
5
2
Site preparation overview ..................................................................................
6
3
Site preparation checklist ..................................................................................
9
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
3
1 Introduction
1
Introduction
Purpose of this document
The purpose of this document is to provide the information needed to fully prepare your
site for the installation and testing of the ÄKTA system.
Acknowledgement of the current document and feedback to GE is a pre-requisite for
the GE service personnel to install and test the ÄKTA system.
WARNING
The product must be installed and prepared by GE service personnel
or a third party authorized by GE.
Feedback to GE
Make sure to read the entire Site Preparation Guide, complete the checklists in Chapter 3
Site preparation checklist, on page 9 and return the document to any of the following:
Region
Email address
FAX number
US/CAN
[email protected]
+ 1 800 721 1673
EMEA
[email protected]
+ 44 (0) 1494 542266
India
[email protected]
+ 91 80 49308866
China
Hong Kong
+ 91 80 49308866
[email protected]
Taiwan
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
+ 852 21006338
+ 886 (2) 2516 5260
5
2 Site preparation overview
2
Site preparation overview
Before the ÄKTA system is delivered, prepare your site according to the instructions in
this chapter.
Installation and testing of the ÄKTA system can be performed under standard conditions
or in a cold room/cold cabinet, as required.
Assign personnel
The following table gives suggestions and summarizes specific site-preparation tasks
that can be divided between two to three company personnel. It is also recommended
that these people assist the GE service personnel during the installation process later
on.
Personnel
Tasks
Site preparation/
installation
coordinator
•
Review the site preparation guide for safety information and system requirements.
•
Choose the site.
•
Coordinate personnel and tasks.
•
Coordinate the installation timing of the ÄKTA system with any domestic
safety procedures and testings.
•
Order required materials.
•
Schedule the installation and inform personnel of the installation date.
•
Review the safety information.
•
Make sure that all customer-provided materials for the installation are
present at the site.
•
Make sure that the installation requirements are met for:
Laboratory personnel/
Primary users
Facilities personnel
6
-
Space at the installation site
-
Environmental conditions
-
Biosafety
-
Ventilation and waste collection
-
Electrical supply
-
Safety and installation materials
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
2 Site preparation overview
Select the site
Select a site that complies with national and international requirements for biosafety.
WARNING
Spread of biological agents. The operator has to take all necessary
actions to avoid spreading hazardous biological agents. The facility
must comply with the national code of practice for biosafety.
Space requirements
Prepare a clean, even and stable working area according to the dimensions shown in
the following table.
Space for
Width (cm)
Depth (cm)
Height (cm)
Weight (kg)
ÄKTA avant
86
71
66
116
ÄKTA pure
54
47
63
53
ÄKTAmicro
150
90
70
55
ÄKTAxpess
1
Instrument
30
60
70
30/unit
Flask holder/
instrument unit
30
25
30
-1
Variable dependent on fluid volume.
Note:
Make sure that there is also a separate space available for computer, monitor,
printer and instrument accessories, for example Fraction collector and
Autosampler.
NOTICE
At least 1 m free working space is needed around the ÄKTA system
during installation.
Environmental requirements
The ÄKTA system is for indoor use only.
Make sure that the installation and operation site comply with the following conditions:
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
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2 Site preparation overview
Condition
Acceptable range
Ambient temperature
4° to 40°C
Atmospheric pressure
84 to 106 kPa (840 to 1060 mbar)
WARNING
A fume hood or similar ventilation system shall be installed when
flammable or noxious substances are used.
Electrical requirements
The number of mains electrical outlets with safety grounding (100-240 V, 50-60 Hz) is
specified in the checklist.
External computer requirements
The use of a GE computer is recommended. A non-GE computer with 64-bit Windows®
operating system is acceptable if it complies with the requirements in the table below.
Components
Specification
Processor
Intel® Core™ i5-2400 with 4 cores, 3.10 GHz
System Memory
4 GB
Hard disc
250 GB
DVD RW
unspecified
Number of serial ports
2
Network card
Extra Network Interface Card
The computer cannot be connected to the network before installation. For special requirements (e.g., remote access) see Chapter 3 Site preparation checklist, on page 9.
User-supplied equipment and
consumables
A list of user-supplied equipment and consumables is found in the checklist section.
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ÄKTA instrument Site Preparation Guide 29-1170-36 AA
3 Site preparation checklist
3
Site preparation checklist
Read the previous sections in this guide before completing the checklist.
Complete the checklist in this chapter to make sure that all necessary preparations have
been made before the installation of the ÄKTA system by GE service personnel.
YES
NO
N/A
Comment/specify
General
Please, specify additional components ready to
be aligned:
•
Fraction collector
•
Sample pump
•
Inlet valve(s)
•
Versatile valve(s)
•
Outlet valve(s)
•
Column valve(s)
•
pH valve
•
Air sensors
•
Other
Will the GE service personnel be required to take
site EHS (Environment, Health and Safety) or security training before doing the installation?
Assigned personnel
Personnel are assigned as specified, see Assign
personnel, on page 6.
Site selection
Space is available as specified, see Space requirements, on page 7.
Instrument
Accessories/additional components
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
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3 Site preparation checklist
YES
NO
N/A
Comment/specify
Computer with monitor and printer
Environmental requirements
The proper environmental conditions are fulfilled
as specified, see Environmental requirements, on
page 7.
Ambient temperature
Humidity
Atmospheric pressure
Fume hood or similar ventilation
(if required)
Electrical requirements
Number of mains electrical outlets: up to
3 for the PC and 1 additional outlet per
instrument unit.
External computer requirements
GE computer purchased and received
Non-GE computer purchased according to External
computer requirements, on page 8.
Has an administrator account been created and a log-in password established for
GE use?
Will the computer be put on a network?
Will the ÄKTA system be networked?
Is there on-site IT support available if needed?
Specify UNICORN version, (e.g., UNICORN 6.4)
User supplied equipment
Access to photocopier
Personal Protective Equipment (PPE)
as required, (e.g., gloves, lab coats, etc.)
Waste flask (1000 ml)
10
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
3 Site preparation checklist
YES
NO
N/A
Comment/specify
4-5 reagent bottles
Additional glassware depending on system
configuration
User supplied consumables
ÄKTA avant/
ÄKTA pure/ÄKTAmicro/ÄKTAxpess:
•
High-quality distilled water (2000 ml)
•
20% ethanol (500 ml)
ÄKTA avant:
•
1% acetone in distilled water (500 ml)
•
1% acetone, 1 M NaCl in distilled water
(1000 ml)
ÄKTA pure:
•
1% acetone, 1 M NaCl in distilled water
(500 ml)
ÄKTAmicro:
•
1% acetone in distilled water (500 ml)
ÄKTAxpess:
•
0.5% acetone in distilled water (500 ml)
•
100% methanol (500 ml)
Additional information (filled in by customer):
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
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3 Site preparation checklist
Customer contact information
Add your contact information to the following table.
Date (dd-mmm-yyyy)
Company/Customer name
Company/Customer
representative
Name
Address
Email
Phone number
Customer experience level
12
Beginner
Intermediate
Advanced
ÄKTA instrument Site Preparation Guide 29-1170-36 AA
For local office contact information, visit
www.gelifesciences.com/contact
GE Healthcare Bio-Sciences AB
Björkgatan 30
751 84 Uppsala
Sweden
www.gelifesciences.com/AKTA
GE and GE monogram are trademarks of General Electric Company.
ÄKTA is a trademark of General Electric Company or one of its subsidiaries.
Intel is a trademark of Intel Corporation.
Windows is a trademark of Microsoft Corporation.
All other third party trademarks are the property of their respective owner.
Any use of UNICORN is subject to GE Healthcare Standard Software End-User
License Agreement for Life Sciences Software Products. A copy of this Standard
Software End-User License Agreement is available on request.
© 2014 General Electric Company – All rights reserved.
First published September 2014
All goods and services are sold subject to the terms and conditions of sale of
the company within GE Healthcare which supplies them. A copy of these terms
and conditions is available on request. Contact your local GE Healthcare representative for the most current information.
GE Healthcare Europe GmbH
Munzinger Strasse 5, D-79111 Freiburg, Germany
GE Healthcare UK Limited
Amersham Place, Little Chalfont, Buckinghamshire, HP7 9NA, UK
GE Healthcare Bio-Sciences Corp.
800 Centennial Avenue, P.O. Box 1327, Piscataway, NJ 08855-1327, USA
GE Healthcare Japan Corporation
Sanken Bldg. 3-25-1, Hyakunincho Shinjuku-ku, Tokyo 169-0073, Japan
29-1170-36 AA 09/2014 a1941