CARDIOVASCULAR SYSTEM Circulation Blood Vessels and Structure Starling’s Law Venous Return and it’s Mechanisms Blood Pooling LEARNING OBJECTIVES 1. Can I identify the differences between blood vessels? 2. Am I able to explain the different mechanisms of Venous Return? CIRCULATION • SYSTEMIC CIRCULATION • Oxygenated blood from the left ventricle to the body tissues and deoxygenated blood back to the right atrium • PULMONARY CIRCULATION • Deoxygenated blood from the right ventricle to the lungs and oxygenated blood back to the left atrium BLOOD VESSELS AND STRUCTURE Arteries are the largest blood vessels, as they get further away from the heart they reduce in size to become arterioles and finally into capillaries (one cell thick to allow gaseous exchange) Capillaries then flow into larger venules and then into even larger veins before entering the right atrium from either the superior vena cava (from the upper body) or inferior vena cava from the lower body BLOOD VESSELS AND STRUCTURE BLOOD VESSELS ARTERIES transport oxygenated blood away from the heart and towards tissue/muscles • VEINS transport deoxygenated blood back to the heart • This is true with the exception of the Pulmonary Artery (carries deoxygenated blood) This is true with the exception of the Pulmonary Vein (carries oxygenated blood) CAPILLARIES bring blood directly into contact with the tissues where O2 and CO2 are exchanged BLOOD VESSELS AND STRUCTURE All blood vessels have 3 layers (apart from singlewalled capillaries) Arteries and arterioles have a large middle layer of smooth muscle (involuntary muscle within blood vessel walls) to allow them to vasodilate (widening of arteries) and vasoconstrict (narrowing of arteries) to regulate blood flow Arterioles have a ring of smooth muscle surrounding the entrance to the capillary networks to control blood flow. These are pre-capillary sphincters, they vasodilate and vasoconstrict to regulate blood flow BLOOD VESSELS AND STRUCTURE Larger veins have pocket valves to prevent backflow of blood and direct blood back to the heart Venules and veins have a thinner muscular layer allowing them to venodilate (widening of veins) and venoconstrict (narrowing of veins) and a thicker outer layer to help support the blood that sits within each pocket valve STARLING’S LAW • STARLING’S LAW This states that stroke volume is dependent upon venous return. If VR increases, SV increases. If VR decreases then SV decreases. If SV increases or decreases, so does Q. Therefore, VR will determine SV and Q At rest VR is sufficient to maintain SV and Q to supply the demand for O2. During exercise the pressure of blood in the veins is too low to maintain VR and then SV and Q decrease Therefore the body needs additional mechanisms to help blood return to the heart against gravity to increase VR and so SV VENOUS RETURN AND IT’S MECHANISMS Pocket Valves • Prevent backflow of blood and direct it back to the heart Muscle Pump • Veins are situated between skeletal muscle which help push blood back to the heart when they contract and relax Respiratory Pump • Pressure changes in the thorax and abdomen during exercise. The increase in pressure in the abdomen, squeezes large veins in that area and forcing blood back to the heart Smooth Muscle • Contraction and relaxation of smooth muscle in the middle layer of veins helps push blood back to the heart Gravity • Blood from the upper body is aided by gravity as it descends to the heart BLOOD POOLING VR requires a force to push the blood back to the heart. If there is insufficient force then the blood will sit in the pocket valves in the veins. This is Blood Pooling At rest gravity, pocket valves and smooth muscle are enough to maintain VR at rest, but not during or immediately after exercise Therefore, the skeletal and respiratory pumps are needed to maintain VR during exercise and immediately after exercise In order for this to happen, an active cool down must take place to maintain these two pumps and help maintain VR and redistribute Q to prevent blood pooling VENOUS RETURN’S IMPACT ON THE QUALITY OF PERFORMANCE Venous Return (VR) is important to performance as it determines SV and Q If SV/Q decreases, oxygen transport to the working muscles decreases, which reduces the ability to contract/work aerobically The impact on performance is that exercise intensity has to be reduced or muscles will have to work anaerobically, which will result in muscle fatigue. A good VR in anaerobic activities will speed up recovery and therefore allow performers to work anaerobically for longer. HOMEWORK Complete exam questions from handout
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