A Serological Test for Tuberculosis in NHPs Intuitive TB ELISA* Reliable Detection of TB-specific Antibodies The health of your nonhuman primate (NHP) colony is critical to the validity of your studies, as well as protecting your valuable research investment and their human caretakers. Routine screening for Mycobacterium tuberculosis (TB) relies on the eyelid tuberculin test, the only approved method for NHPs. The overall lack of sensitivity and specificity of this test has lead to a need for additional screening methods. Intuitive Bioscience’s TB ELISA is a simple but high-throughput screening method with highly accurate results. Within 3 hours, up to 96 animals can be screened for the presence of antibodies to TB-specific antigens. The test is easy to perform, uses standard lab equipment, can be completed on the same day, and is a noninvasive method. This means even animals on a study can undergo TB screening with a simple blood draw. Figure 1. Results from Intuitive TB ELISA from 272 TST negative samples from several colonies. Positive samples include 20 TST positive animals from naturally and experimentally infected animals. BENEFITS ffordable: Screen your A colony for under $15 per sample How it works Reliable: Highly sensitive and specific assay Easy: Run as a standard ELISA Rapid: Results in about 4 hours Figure 2. Assay steps performed in the Intuitive TB ELISA. The Intuitive TB ELISA uses our proprietary mix of novel biomarkers selected for their specificity for tuberculosis-infected NHPs. With 98% specificity and greater than 90% sensitivity, you can augment your TST protocol and identify latently infected animals before a devastating outbreak can occur. * Experimental product, not approved by USDA. Ordering Information Please call or email for sample testing service. L713 rev 03Mar13 Product Product Name Compatible with most NHPs including: • Rhesus Macaque • Cynomolgus Macaque • Southern Pig-tailed Macaque • African Green Monkey • Olive Baboon • Vervet Description US$ 15-1002 Intuitive TB ELISA 1 Plate, for up to 96 samples 1399 15-1003 Intuitive TB ELISA 5 Plates, for up to 5 x 96 samples 6645 12-1013 Intuitive TB Sample Testing Service TB Testing Service, per sample 25 888.700.7442 608.204.8730 [email protected] TOLL-FREE IN NORTH AMERICA OUTSIDE OF NORTH AMERICA RE:”CSA: SIMIAN TB” 5500 Nobel Drive, Suite 220 • Madison WI 53711 Phone: 608.204.8730 Fax: 608.204.8740 www.IntuitiveBio.com
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