Self Assessment for Antibiotics
1. All of the following are examples of antibiotics which target the cell wall except:
a. Cephalosporin
b. Vancomycin
c. Azithromycin
d. Penicillin
2. Which of the following is an antibiotic that contains a beta-lactamase inhibitor?
a. Ampicillin
b. Amoxicillin plus clavulanic acid
c. Ticarcillin
d. Sulfamethoxazole plus Trimethoprim
3. Which of the following agents acts like an injectable tetracycline?
a. Zeven (Dalbavancin)
b. Timentin (ticarcillin plus clavulanic acid)
c. Zyvox (Linezolid)
d. Tigacyl (Tigacycline)
4. Treatment of Community acquired pneumonia is the same as Health Care Acquired Pneumonia
where a third generation cephalosporin and azithromycin can be used to treat.
a. True
b. False
5. All of the following are characteristics of Community acquired MRSA except:
a. Site of infection is primarily skin
b. High risk factors include age <2, close contact sports
c. Shows increase risk of multi-drug resistance
d. Strain type tends to by UA 300-400
Answers:
1. C – Azithromycin actually targets the 50S ribosome not the cell wall. All of the other antibiotics
fall into the cell wall mechanism of action.
2. B – Clavulanic Acid, Sulbactam, and Tazobactam are all agents added to the penicillin
compounds in order to prevent destruction by an enzyme produced by bacteria called betalactamase.
3. D- Tigacyl is a tetracycline like compound that has a distinctive orange color and is the only
available tetracycline like compound in IV formulation.
4. False – Healthcare acquired pneumonia usually involves more resistant strains of organisms and
requires more broad spectrum antibiotics such as Vancomycin and Zosyn to treat efficiently.
5. C- Community acquired MRSA displays all of the characteristics except being multi-drug
resistant. This characteristic is reserved for the health care associated MRSA – causing it to be
far more difficult to treat.