Nucleic Acids Nucleic acids are … ► Informational macromolecules used by all organisms to store hereditary information ► Macromolecules made up of repeating units called nucleotides. ► Only molecules that can produce identical copies of themselves ► Nitrogen containing compounds ► Originally found in the nucleus ► 2 types: DNA and RNA Nucleotide: subunit of nucleic acids ► Molecules that contain a 5-carbon sugar unit, phosphate group and nitrogen base ► The nitrogen bases are purines (adenine A and guanine G) or pyrimidines (cytosine C, thymine T and uracil U) ► DNA has nucleotides containing the bases A, G, C, and T ► RNA has nucleotides containing bases A, G, C, and U ► Sequence of Nitrogen Bases determines the genetic code ► See page 53 Nucleotides Nitrogen bases DNA RNA 3 Differences of DNA and RNA DNA RNA Double stranded (double helix) Single stranded Contains base thymine Contains base uracil (instead of thymine) 5-carbon sugar is deoxyribose 5-carbon sugar is ribose Adenosine Triphosphate (ATP) ► Nucleotide derivative that acts as the primary energy-transferring molecule in living organisms ► Contains the nitrogen base adenine attached to the 5-carbon sugar ribose, which is bound to 3 phosphate groups ► ** we will talk more about ATP in the next few slide shows ATP ► Readings: 52-54 ► Questions on handout
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