PROSPERO International prospective register of systematic reviews
An overview of non hospital interventions for paediatric asthma in less economically
developed countries
Matthew Roberts, Sarah Fissler, Ian Sinha, Justus Simba
Citation
Matthew Roberts, Sarah Fissler, Ian Sinha, Justus Simba. An overview of non hospital interventions for paediatric
asthma in less economically developed countries. PROSPERO 2016:CRD42016046649 Available from
http://www.crd.york.ac.uk/PROSPERO_REBRANDING/display_record.asp?ID=CRD42016046649
Review question(s)
In children under 18 with asthma in less economically developed countries:
Do school based public health interventions reduce 1- unscheduled admissions to hospital 2- exacerbations of asthma
3- use of steroids; when compared to controls
In children under 18 with asthma in less economically developed countries:
Do telemedicine and remote monitoring techniques reduce 1- unscheduled admissions to hospital 2- exacerbations of
asthma 3- use of steroids; when compared to controls
In children under 18 with asthma in less economically developed countries:
Do pharmacy based interventions reduce 1- unscheduled admissions to hospital 2- exacerbations of asthma 3- use of
steroids; when compared to controls
In children under 18 with asthma in less economically developed countries:
Does non medical staff based interventions reduce 1- unscheduled admissions to hospital 2- exacerbations of asthma
3- use of steroids ; when compared to controls
Searches
We will search Cochrane database of systematic reviews and Scopus databases for systematic reviews and
randomised controls trials.
The search strategy will include terms relating to the intervention and population of interest.
Types of study to be included
We will include systematic reviews; randomised control trials, non-randomised control trials.
Observational type studies will not be eligible.
Condition or domain being studied
Paediatric asthma in less economically developed countries.
Participants/ population
Inclusion: Children (<18 years) with asthma in less economically developed countries
Exclusion: Patients over 18 years AND patients in developed countries.
Intervention(s), exposure(s)
We are interested in studying a number of interventions:
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1) School based interventions: This may include but is not limited to, training teachers to provide asthma education
for/ check inhaler technique in pupils.
2) Telemedicine and remote monitoring techniques: This may include but is not limited to, remote clinics via
electronic communication
3) Pharmacy based interventions: This may include but is not limited to, pharmacy staff carrying out asthma reviews/
reviewing inhaler technique
4) Non medical staff based interventions: This may include but is not limited to, community/ peer group
interventions.
Comparator(s)/ control
A control group of paediatric patients in less economically developed countries who are not exposed to the
intervention of interest.
Context
Studies on patients based in the community on our community of patients as described.
Outcome(s)
Primary outcomes
1- unscheduled admissions to hospital
2- exacerbations of asthma
3- use of steroids
Secondary outcomes
Quality of life assessments
Data extraction, (selection and coding)
Titles and/or abstracts of studies retrieved using the search strategy and those from additional sources will be
screened independently by two review authors to identify studies that potentially meet the inclusion criteria outlined
above. The full text of these potentially eligible studies will be retrieved and independently assessed for eligibility by
two review team members. Any disagreement between them over the eligibility of particular studies will be resolved
through discussion with a third reviewer
Two independent reviewers with use AMSTAR to assess quality of systematic reviews and 'Cochrane Risk of bias
tool' for randomised control trials.
Data to be extracted includes: 1) study population 2) Details of intervention 3) measures outcomes 4) results 5)
information required for completion of above tools.
Risk of bias (quality) assessment
Two independent reviewers with use AMSTAR to assess quality of systematic reviews and 'Cochrane Risk of bias
tool' for randomised control trials
Strategy for data synthesis
We will provide a narrative synthesis of the findings from the included studies, structured around the type of
intervention, target population characteristics, type of outcome and intervention content.
Analysis of subgroups or subsets
None planned
Contact details for further information
Dr Roberts
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[email protected]
Organisational affiliation of the review
Alder Hey Childrens Hospital Liverpool
http://www.alderhey.nhs.uk/
Review team
Dr Matthew Roberts, Alder Hey Childrens Hospital Liverpool
Dr Sarah Fissler, Alder Hey Childrens Hospital Liverpool
Dr Ian Sinha, Alder Hey Childrens Hospital Liverpool
Dr Justus Simba, Jomo Kenyatta University of Agriculture + Technology
Anticipated or actual start date
26 August 2016
Anticipated completion date
24 August 2018
Funding sources/sponsors
Nil
Conflicts of interest
None known
Language
English
Country
England, Kenya
Subject index terms status
Subject indexing assigned by CRD
Subject index terms
Asthma; Child; Developed Countries; Developing Countries; Humans; Pediatrics
Stage of review
Ongoing
Date of registration in PROSPERO
29 August 2016
Date of publication of this revision
29 August 2016
Stage of review at time of this submission
Preliminary searches
Piloting of the study selection process
Formal screening of search results against eligibility criteria
Data extraction
Risk of bias (quality) assessment
Data analysis
Started
Completed
No
No
No
No
No
No
No
No
No
No
No
No
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PROSPERO
International prospective register of systematic reviews
The information in this record has been provided by the named contact for this review. CRD has accepted this information in good
faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record,
any associated files or external websites.
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