RADIOCHEMICAL
PRODUCTS
RELIABLE SOURCE FOR
HIGH-QUALITY RADIOISOTOPES
EXCELLENCE DEDICATED
TO NUCLEAR MEDICINE,
HEALTHCARE & ENVIRONMENT
Flexibility & just in time production and delivery 7 d / 7 d
• Never out-of-spec,
Outstanding quality products
• For the last 5 years.
High consistency and reliability in our work
MOLYBDENUM - 99
• Without any single day of interruption,
IODINE -131
Because the health of your patients can’t wait, IRE has supplied
some 20 % of the world demand of 99Mo and 131I.
Thanks to:
BR-2 Belgium
LVR-15 Czech Republic
MULTIPLE RESEARCH REACTORS
Brussels
VERY WELL CONNECTED
TO INTERNATIONAL AIRPORTS
ON SITE TRANSPORT COMPANY
COMMITED EMPLOYEES
YOUR SUCCESS IS OUR PASSION
YTTRIUM - 90
HFR The Netherlands
MEDICAL USE
The properties of iodine-131 make it more suitable for therapy than diagnosis. It is
mainly used in the treatment of thyroid cancer and certain forms of hyperthyroidism.
PRODUCT SPECIFICATIONS
• P
HYSICAL FACTS
The decay scheme for 131I production
131
53
I
8 days
606.3 keV max (89.9 %)
131
364.439 KeV
(81.7%)
54
131
54
Xe
Xe
• C
HEMICAL FACTS
Chemical form: NaI
Solution molarity:
0.1M NaOH (pH 9-13)
Activity: at the customer’s request
160,2 GBq / ml ( at calibration date)
A
ppearance: clear and colourless
solution, precipitate free
S
pecific Activity: no carrier and no
additive
555GBq / ml (at expiry
date)
R
adionuclidic purity (at calibration
date better than US and European
Pharmacopoeia)
Total emitters / 131I 1*10-3
Radiochemical purity: 131I as I- 97%
• P
RACTICAL FACTS
Calibration : total activity to be specified at a specific date/time by the user
Delivery : according to customer requirements
Contact : [email protected]
MEDICAL USE
Manufacturing of 99Mo / 99mTc generator (Tc-99m kits) for producing radiopharmaceuticals to examine the brain, kidney, heart, bone, liver, and lung.
PRODUCT SPECIFICATIONS
• P
HYSICAL FACTS
The decay sheme for 99Mo production
decay,
Mo
99
t1/2 = 66 hours
99m
99
Tc
Tc
transition, t1/2 = 6.01 h
decay,
t1/2 = 211100 years
Ru
99
• C
HEMICAL FACTS
C
hemical form: Na2MoO4
S
olution molarity: 0.2M NaOH
Activity: at the customer’s request
17,4 GBq / ml (at expiry date)
A
ppearance: clear and colourless or
almost colourless solution, precipitate free
Specific Activity: carrier free 87,3 GBq / ml (at expiry date)
R
adionuclidic purity (at calibration
date): 131I / 99Mo 5*10-5
103
Ru / 99Mo 5*10-5
89
Sr + 90Sr / 99Mo 6*10-7
All other / emitters / 99Mo 1*10-4
Total α emitters / 99Mo 1*10-9
R
adiochemical purity: 99Mo as MoO42and TcO41- 97%
• P
RACTICAL FACTS
Calibration : total activity to be specified at a specific date/time by the user
Delivery : according to customer requirements
Contact : [email protected]
MEDICAL USE
Yttrium-90 is suitable as the therapeutic agent on a monoclonal antibody for targeting
cancer cells (non-Hodgkin’s cancers), or as the active ingredient in glass microspheres
used in treating liver tumors.
PRODUCT SPECIFICATIONS
• P
HYSICAL FACTS
The decay scheme for 90Y production
Sr (t1/2 = 28.78y)
90
-
(Emax 0.546 MeV)
Y (T1/2 2.67 d)
90
-
(Emax 2.28 MeV)
Zr (stable)
90
• CHEMICAL FACTS
Chemical Form: YCl3
Chemical Purity (at production date):
Solution molarity: 0.04 M HCl
(Ca, P) 100 μg / Ci for each
Activity: at the customer’s request 27,8 GBq / ml (at production date)
(Ba, Mg) 50 μg / Ci for each
Specific Activity: carrier free
( Zn, Al, Cu, Fe, Cd, Cr, Pb) 20 μg /
Ci for each
A
ppearance: clear and colorless solution, precipitate free
( Ce, Co, La, Ni, Sr, Zr) 10 μg /Ci for each
R
adionuclide purity
(at calibration date):
(Zn+Fe+Cu+Pb) 20 μg / Ci
Sr / 90Y 1.8* 10-7
90
Total γ emitters /90Y 1.0* 10-4
• P
RACTICAL FACTS
Calibration : total activity to be specified at a specific date/time by the user
Delivery : according to customer requirements
Contact : [email protected]
Avenue de l’Espérance 1 | B-6220 Fleurus | Belgium
T. +32 (0)71 82 95 96
F. +32 (0)71 81 38 12
www.ire.eu
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