3/8/2011 Do Cell Phones Truly Affect Cellular Function? “Far more people in India have access to a mobile phone than to a toilet.” Amy Van Gheem, MD, Lindsay Penrose, PhD, Lisa Welch, MS and Sam Prien, PhD UN University Study, 2010 Previous Research Many possible health outcomes Mild local warmth Cancer Lower sperm count INTERPHONE Study ↑ risk of glioma at the highest exposure Otherwise no increased glioma or meningioma risk due to mobile phone use Int J Epidemiol 2010:12010:1-20 Long--Term Goal Long To determine if cell phones pose any threat to reproduction Objectives Establish the field strength of the radiant energy source associated with mobile phone use Determine if direct exposure of cultured cells to these fields influenced cell physiology 1 3/8/2011 Preliminary Study Results Field Intensities of Three Cell Phone Types Measurement of 67 cell phones for the presence of radiant energy fields 0.8 Electromagnetic fields (EMF) Radiofrequency fields (RF) Background levels 0.7 0.4 a 0.3 0.2 Non-Smart I-phone Results Activation of Peritoneal Macrophages In Vitro 24 hr after Exposure to Radian Energy Fields 70 60 Percentage 50 i a h d 40 30 0 non-activated 90 h 80 d g b control phone e a EMF f c 0 intermediate intermediate activated Cell phones appear to produce little to no EMF However, cell phones produce significant radiofrequency (RF) fields Macrophages activated by 10 non-activated EMF c 10 i 50 phone Conclusions 100 60 control g b 20 Activation of Peritoneal Macrophages In Vitro 72 h after Exposure to Radian Energy Fields 70 d d Results 20 Smart Phone Type Macrophage activation determined at 24 and 72 hrs 30 RF a 0 High EMF (positive control) Direct contact with cell phone No exposure (negative control) 40 a 0.1 Macrophages harvested from mice Macrophages exposed (1 hr) to: f 0.5 EMF = .2 uG RF= 0 watts Percentage EMF 0.6 Cell Culture Experiments e e 0.9 EMF (uG) and RF (watts) High EMF Cell phones activated 2 3/8/2011 Discussion Questions? At close range in vitro, cell phones appear to influence cellular function However, it is unclear if this translates to cells in vivo, especially reproductive tissue which is normally more distant Future studies are warranted to determine the possible influences cell phones might have on reproduction 3
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