Guanidines
L-Arginine, a natural α-amino acid, is a prominent guanidine compound, which has
a significant role in binding to DNA in protein. It is also known that guanidine alkaloids such as saxitoxin and tetrodotoxin are made biosynthetically from arginine.
Recently it has been reported that peptides containing many arginines have high
cell permeability,1) so applications in medicinal chemistry or biochemistry are
expected.
1) J. Am. Chem. Soc., 2004, 126, 9506; J. Am. Chem. Soc., 2005, 127, 1114.
Guanidinating Reagents
. HCl
N
N
N
H2N C NH
HN
N
N
H
N
N
O
HN
OC(CH3)3
O
N
H
O
1-Amidinopyrazole Hydrochloride
N-(tert-Butoxycarbonyl)N-(Carbobenzoxy)[A2055]
1H-pyrazole-1-carboxamidine 1H-pyrazole-1-carboxamidine
[B4028]
[C2709]
New
New
O
(CH3)3CO
N
N
O
O
O
N
N
OC(CH3)3
H
N,N'-Bis(tert-butoxycarbonyl)1H-pyrazole-1-carboxamidine
[B3619]
N
N
N
O
N
H
O
N,N'-Bis(carbobenzoxy)1H-pyrazole-1-carboxamidine
[B3605]
Bioactive Compounds
NH
CH3
N
NH
N
H
CH3
NH
NH2
H2N
. HCl
Metformin Hydrochloride
[M2009]
New
H2NO2S
NH
HN
NH
N
H
H
N
NH
.
NH
2CH3COOH
N
H
N
H
Cl
S
C NH2
Sulfaguanidine
[S0464]
NH
N
Famotidine
[F0530]
S
N
H
N
NH2
CH3
H2N
OH
O
H C
OH
OH
N
H
CH3
H
NH OH
O
N
H
Cimetidine
[C1252]
O
NH
Chlorhexidine
Diacetate
[C2511]
Dihydrochloride [C1254]
S NH
NC N C NHCH2CH2SCH2
O
Cl
NH
O
NHCH3
NH
O
H2N
. H2SO4
Agmatine Sulfate
[A0310]
N
H
H
N
NH
NH2
. xH2O
Zanamivir Hydrate
[Z0023]
New
H3 C
HO
HO
HO
O
O
OH
O
OH
NH2
OH
NH
O
NHCH3
NH
OH
NH
NH
NH2
. 11/2 H2SO4
Streptomycin Sulfate
[S0585]
Guanidines
Guanidine Blocks
NH
.X
N
NH2
H
X=HCl
1-Methylguanidine Hydrochloride
[M0336]
X=1/2H2SO4 1-Methylguanidine Sulfate [M1691]
CH3
NH
.X
H2 N
NH2
X=1/2H2CO3 Guanidine Carbonate
X=HCl
Guanidine Hydrochloride
Guanidine Nitrate
X=HNO3
X=1/2H3PO4 Guanidine Phosphate
X=1/2H2SO4 Guanidine Sulfate
X=HSCN
Guanidine Thiocyanate
X=NH2SO3H Guanidine Sulfamate
NH
N
NH2
H
Cyanoguanidine
[C0454]
NH
. H2SO4
CH3
N
CH3
NH
CH3
N
2
NH
N
N
CH3 CH3
1,1,3,3-Tetramethylguanidine
[T0148]
O
CH3
H
N
H
N
(wetted with ca. 25% Water)
[M0749]
OH
HN
NH2
CH3
C NH
C NH2
Phenylbiguanide
[P1002]
N
H
OH
OH
H
N
H
N
NH
NH2
NH
1-(o-Tolyl)biguanide
[T0314]
NH2
H-Arg-OH
H-Arg-OH·HCl
H-Arg-OMe·2HCl
Boc-Arg-OH·HCl Monohydrate
Boc-Arg-pNA·HCl
Bz-Arg-OEt·HCl
Z-Arg-OH
α,ω-Di-Z-Arg-OH
Z-Arg(Z)2-OH
Dnp-Arg-OH
Fmoc-Arg(Tos)-OH
Fmoc-Arg(Pbf)-OH
H-Arg(NO2)-OH
H-Arg(NO2)-OMe·HCl
Tos-Arg-OH
Tos-Arg-OMe·HCl
NH
NH
Guanidoacetic Acid
[G0167]
(S)-(-)-2-Guanidinoglutaric Acid
[G0265]
NH
O
H
N
H2N
NH
NH
NO2
NH
1-Methyl-3-nitroguanidine
O
HO
O
L-Arginine
1,1-Diethylguanidine
Sulfate
[D2035]
CH3
H2N
. H2SO4
NH2
CH3
2
1,1-Dimethylguanidine
Sulfate
[D1799]
NH
.X
N
NH2
H
X=H2CO3
Aminoguanidine Bicarbonate
[A0307]
X=1/2H2SO4, xH2O
Aminoguanidine Sulfate Hydrate
[A0309]
X=HCl
Aminoguanidine Hydrochloride
[A1129]
H2N
NH
NH
CH3
NH
NH2 . HCl
N
N
H
H
1,3-Diaminoguanidine
Hydrochloride
[D1912]
H2N
NC
H2N
[G0161]
[G0162]
[G0164]
[G0165]
[G0166]
[G0230]
[G0022]
H2 N
[A0526]
[A0528]
[A2017]
[B1626]
[B1497]
[B0853]
[C0757]
[D1179]
[T0755]
[D1040]
[F0883]
[F0729]
[N0660]
[N0661]
[T0684]
[T0330]
O
N
H
OH
NH2
D-Arginine
H-D-Arg-OH
H-D-Arg-OMe·2HCl
Boc-D-Arg-OH·HCl Monohydrate
Z-D-Arg-OH
Fmoc-D-Arg(Pbf)-OH
[A1029]
[A2016]
[B2204]
[C2131]
[F0875]
If you need products not listed in our catalog, please contact us. We can provide any other product on your request.
Ordering and Customer Service
Tel
Fax
E-mail
: 800-423-8616 • 503-283-1681
: 888-520-1075 • 503-283-1987
: [email protected]
Tel
: +32 (0)3 735 07 00
Fax
: +32 (0)3 735 07 01
E-mail : [email protected]
Tel
: +44 (0)1865 784560
Fax
: +44 (0)1865 784561
E-mail : [email protected]
Tel
: 800-988-0390 • 021-67121386
Fax
: 021-6712-1385
E-mail : [email protected]
Tel
Fax
: 781-239-7515
: 781-239-7514
Tel
: +49 (0)6196 64053-00
Fax
: +49 (0)6196 64053-01
E-mail : [email protected]
Tel
: +91 (0)44-2262 0909
Fax
: +91 (0)44-2262 8902
E-mail : [email protected]
Tel
: +81 (0)3-5640-8878
Fax
: +81 (0)3-5640-8902
E-mail : [email protected]
www.TCIchemicals.com
RR024E 20130627 Printed in Japan