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BIOLOGY 12
NOVEMBER 2000
COURSE CODE = BI
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© 2000 Ministry of Education
Question 1:
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1.
(6)
Question 2:
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2.
(6)
Question 3:
.
3.
(6)
Question 4:
.
4.
(8)
Question 5:
.
5.
(10)
Question 6:
.
6.
(5)
Question 7:
.
7.
(7)
Question 8:
.
8.
(2)
BIOLOGY 12
NOVEMBER 2000
COURSE CODE = BI
GENERAL INSTRUCTIONS
1. Electronic devices, including dictionaries and pagers, are not permitted in the
examination room.
2. All multiple-choice answers must be entered on the Response Form using an
HBÊpencil. Multiple-choice answers entered in this examination booklet will not
be marked.
3. For each of the written-response questions, write your answer in ink unless
otherwise instructed in the space provided in this booklet.
4. Ensure that you use language and content appropriate to the purpose and audience
of this examination. Failure to comply may result in your paper being awarded a
zero.
5. This examination is designed to be completed in two hours. Students may,
however, take up toÊ30 minutes of additional time to finish.
BIOLOGY 12 PROVINCIAL EXAMINATION
Value
Suggested
Time
PART A: 50 multiple-choice questions
50
45
PART B: 8 written-response questions
50
75
1. This examination consists of two parts:
Total:
100 marks
120 minutes
THIS PAGE INTENTIONALLY BLANK
PART A: MULTIPLE CHOICE
Value: 50 marks
Suggested Time: 45 minutes
INSTRUCTIONS: For each question, select the best answer and record your choice on the Response
Form provided. Using an HB pencil, completely fill in the circle that has the letter
corresponding to your answer.
Use the following diagram to answer question 1.
1. The organelle above is
A.
B.
C.
D.
a nucleolus.
a mitochondrion.
a Golgi apparatus.
an endoplasmic reticulum.
OVER
-1-
Use the following diagram to answer question 2.
X
2. One function of structure X is to
A.
B.
C.
D.
replicate DNA.
produce amylase.
transcribe mRNA.
hydrolyze nuclease.
Use the following diagram to answer question 3.
X
Y
W
Z
3. Which of the structures manufactures rRNA?
A.
B.
C.
D.
W
X
Y
Z
-2-
4. A solution with a high concentration of hydrogen ions ( H + ) is
A.
B.
C.
D.
basic.
acidic.
neutral.
isotonic.
5. Which of the following is produced when glucose and fructose are chemically joined to form
sucrose?
A.
B.
C.
D.
water
nucleotide
peptide bond
hydrogen bond
6. Which diagram illustrates an energy storage product of the liver?
A.
O
O
O
O
O
O
O
CH 2
O
O
CH2
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
CH 2
CH2
O
O
B.
O
O
O
O
O
OH
CH3
CH3
O
O
C.
O
O
O
O
O
O
O
O
O
O
D.
P
OVER
-3-
7. Which of the following is the correct matching of base pairs in DNA?
A.
B.
C.
D.
cytosineÑguanine; uracilÑadenine
cytosineÑadenine; thymineÑuracil
adenineÑguanine; cytosineÑthymine
adenineÑthymine; guanineÑcytosine
8. Which of the following is a component of a DNA molecule?
A.
B.
C.
D.
ATP
uracil
ribose
nucleotide
9. In DNA replication, the term ÒunzippingÓ refers to
A.
B.
C.
D.
denaturing the DNA helix.
unwinding the mRNA from the DNA after transcription.
breaking the bonds between complementary DNA strands.
breaking the bonds between the sugar and phosphate molecules.
10. Which of the following is a valid contrast between RNA and DNA?
RNA
DNA
A.
helical
not helical
B.
sugar is ribose
sugar is deoxyribose
C.
found only in the nucleus
found in the nucleus and the cytoplasm
D.
thymine is one of its bases
uracil is one of its bases
11. Transcription is the production of
A.
B.
C.
D.
a polypeptide chain.
a new DNA molecule.
multiple copies of a single type of enzyme.
an RNA molecule complementary to a section of DNA.
-4-
Use the following chart to answer questions 12 and 13.
Three-letter codons of messenger RNA and the amino acids specified by the codons
AAU
AAC
Asparagine
CAU
CAC
Histidine
GAU
GAC
Asparatic acid
UAU
UAC
Tyrosine
AAA
AAG
Lysine
CAA
CAG
Glutamine
GAA
GAG
Glutamate
UAA
UAG
Stop
ACU
ACC
ACA
ACG
Threonine
CCU
CCC
CCA
CCG
Proline
GCU
GCC
GCA
GCG
Alanine
UCU
UCC
UCA
UCG
Serine
AGU
AGC
Serine
UGU
UGC
Cysteine
Arginine
AGA
AGG
Arginine
GGU
GGC
GGA
GGG
UGA
UGG
Stop
Tryptophan
AUU
AUC
AUA
Isoleucine
UUU
UUC
Phenylalanine
AUG
Methionine
UUA
UUG
Leucine
CGU
CGC
CGA
CGG
CUU
CUC
CUA
CUG
Leucine
GUU
GUC
GUA
GUG
Glycine
Valine
12. Read the following DNA sequence left to right.
TAT C T T
Which amino acid sequence is coded for?
A.
B.
C.
D.
tyrosine, valine
isoleucine, valine
tyrosine, glutamate
isoleucine, glutamate
13. If a cell grown in the presence of radioactively-labelled uracil is actively producing protein
containing lysine, which of the following is correct?
A.
B.
C.
D.
The lysine produced is radioactive.
The codons for lysine are radioactive.
The DNA code for lysine is radioactive.
The anticodons for lysine are radioactive.
OVER
-5-
14. Disorganized and uncontrolled cell growth is called
A.
B.
C.
D.
anaplasia.
metastasis.
vascularization.
contact inhibition.
15. Which of the following is not one of the recognized Òseven danger signalsÓ that may indicate
the presence of cancer?
A.
B.
C.
D.
headache
persistent cough
a sore that will not heal
change in a moleÕs appearance
16. During carcinogenesis, an initiator
A.
B.
C.
D.
triggers metastasis.
promotes vascularization.
brings about DNA mutation.
provides an environment for tumour formation.
17. A virus may be able to bring about carcinogenesis since it can
A.
B.
C.
D.
denature DNA.
add a gene to the host cell.
reproduce within the host cell.
cause the death of its host cell.
18. The movement of an oxygen molecule throughout a cell occurs by
A.
B.
C.
D.
osmosis.
diffusion.
pinocytosis.
facilitated transport.
-6-
Use the following diagram to answer question 19.
time
19. Which of the following situations is an example of the process shown above?
A.
B.
C.
D.
the absorption of glucose by the cell
red blood cells moving in the bloodstream
the excretion of hydrogen ions in the kidney
the secretion of neurotransmitters at the synapse
OVER
-7-
Use the following diagram to answer questions 20 and 21.
Side B
Side A
(solution 1)
(solution 2)
membrane
20. The diagram shows two solutions containing solutes and
dissolved in water and
separated by a membrane. If the membrane is only permeable to water, which of the following
will occur?
will move from side A to side B.
A.
B. The concentration of
on side A will increase.
C. The concentration of
on side B will increase.
D. Final amounts of ,
and water will be equal on each side.
21. If the membrane is permeable to
A.
B.
C.
D.
but not to
swell and possibly burst.
become isotonic to side B.
remain hypertonic to side B.
become hypotonic to side B.
-8-
or water, side A will
Use the following diagram to answer question 22.
X
22. The structure labelled X is the
A.
B.
C.
D.
appendix.
epiglottis.
duodenum.
gall bladder.
________________________________________________
23. Which of the following is not a function of the liver?
A.
B.
C.
D.
producing bile
secreting insulin
detoxifying blood
making blood proteins
OVER
-9-
Use the following diagram to answer question 24.
X
24. The vessel labelled X is the
A.
B.
C.
D.
aorta.
renal vein.
hepatic vein.
hepatic portal vein.
________________________________________________
25. Which of the following is normally found in blood plasma but not in lymph?
A.
B.
C.
D.
salt
urea
oxygen
platelets
- 10 -
Use the following diagram to answer question 26.
X
26. If osmotic pressure is a constant 25 mm Hg, which of the following best describes what
occurs at X?
BLOOD PRESSURE
EVENT
(mm Hg)
A.
nutrients move from the capillaries to the tissues
10
B.
nutrients move from the capillaries to the tissues
40
C.
wastes move into the capillaries from the tissues
25
D.
wastes move into the capillaries from the tissues
40
OVER
- 11 -
Use the following diagram to answer questions 27 and 28.
X
Y
27. Structure X carries blood to the
A.
B.
C.
D.
lungs.
heart tissue.
lower body.
upper body.
28. Structure Y is the
A.
B.
C.
D.
septum.
right ventricle.
coronary artery.
chordae tendineae.
- 12 -
Use the following diagram to answer question 29.
Y
Z
X
W
29. In which of the following structures are cilia found?
A.
B.
C.
D.
W
X
Y
Z
OVER
- 13 -
Use the following graph to answer question 30.
pressure in
thoracic cavity
X
Y
time
30. The graph shows changes in air pressure in the thoracic cavity during breathing. Which of the
following occurs between times X and Y?
A.
B.
C.
D.
rib muscles relax and diaphragm relaxes
rib muscles relax and diaphragm contracts
rib muscles contract and diaphragm relaxes
rib muscles contract and diaphragm contracts
- 14 -
Use the following graph to answer question 31.
+40
0
membrane potential
(millivolts)
Ð65
X
Y
time (milliseconds)
31. What occurs within the neuron between time X and time Y?
A.
B.
C.
D.
Sodium ions move into the cell.
Calcium ions move out of the cell.
Potassium ions move out of the cell.
Large, negatively-charged ions move into the cell.
________________________________________________
32. Resting potential is characterized by
A.
B.
C.
D.
the opening of the sodium gates.
more potassium ions outside the membrane than inside.
an equal number of sodium ions on both sides of the membrane.
more sodium ions on the outside than on the inside of the membrane.
OVER
- 15 -
Use the following diagram to answer question 33.
33. The event that occurs next is the movement of
A.
B.
C.
D.
sodium ions ( Na + ) into the post-synaptic neuron.
calcium ions ( Ca 2+ ) into the pre-synaptic ending.
potassium ions ( K + ) out of the post-synaptic ending.
bicarbonate ions ( HCO3 − ) into the receptors of the pre-synaptic membrane.
Use the following diagram to answer question 34.
X
Y
W
Z
34. Which of the following structures sorts incoming sensory stimuli and channels them to the
appropriate part of the brain?
A.
B.
C.
D.
W
X
Y
Z
- 16 -
35. The hypothalamus causes the anterior pituitary to secrete hormones by
A.
B.
C.
D.
negative feedback.
releasing adrenalin.
releasing hormones.
nervous stimulation.
36. Which of the following is a true statement about the collecting duct?
A.
B.
C.
D.
Water diffuses into it.
It responds to aldosterone.
It is the site of tubular excretion.
The fluid in it becomes hypertonic to blood.
37. In the nephron, the highest concentration of salt is found surrounding the
A.
B.
C.
D.
loop of Henle.
BowmanÕs capsule.
distal convoluted tubule.
proximal convoluted tubule.
Use the following diagram to answer question 38.
X
38. During the process occurring at X, some nutrients are separated from
A.
B.
C.
D.
salts.
water.
wastes.
proteins.
OVER
- 17 -
39. The concentration of urea is lower in the renal vein than in the renal artery because
A.
B.
C.
D.
the kidneys add urea to the blood.
little reabsorption of urea occurs in the nephron.
BowmanÕs capsule removes water from the filtrate.
the peritubular capillary network passes urea to the loop of Henle.
Use the following diagram to answer question 40.
X
Y
W
Z
40. Which of the following glands produces aldosterone?
A.
B.
C.
D.
W
X
Y
Z
- 18 -
Use the following diagram to answer question 41.
X
W
Y
Z
41. In which of the following structures does sperm maturation occur?
A.
B.
C.
D.
W
X
Y
Z
________________________________________________
42. The cells of the seminiferous tubules respond to
A.
B.
C.
D.
luteinizing hormone (LH) and produce sperm.
luteinizing hormone (LH) and produce testosterone.
follicle-stimulating hormone (FSH) and produce sperm.
follicle-stimulating hormone (FSH) and produce testosterone.
43. One function of seminal fluid is to
A.
B.
C.
D.
lower the pH of the uterus.
lower the pH of the vagina.
provide nourishment for the egg.
provide a medium in which sperm swim.
OVER
- 19 -
44. Which part of a mature sperm aids digestion of the outer membrane of an ovum?
A.
B.
C.
D.
tail
head
acrosome
mid-piece
45. Increased muscle strength, enlarged vocal cords and growth of pubic hair are stimulated by
A.
B.
C.
D.
thyroxin.
estrogen.
testosterone.
follicle-stimulating hormone (FSH).
46. The hormone that stimulates the secretion of sex hormones in both sexes is
A.
B.
C.
D.
estrogen.
testosterone.
luteinizing hormone (LH).
human chorionic gonadotropin (HCG).
- 20 -
Use the following diagram to answer question 47.
W
X
Y
Z
47. In which of the labelled structures is an egg produced?
A.
B.
C.
D.
W
X
Y
Z
________________________________________________
48. The function of the corpus luteum is to
A.
B.
C.
D.
help maintain the endometrium.
secrete luteinizing hormone (LH).
produce human chorionic gonadotropin (HCG).
produce more follicle-stimulating hormone (FSH).
49. Days 15 to 28 of the 28-day uterine cycle are referred to as the
A.
B.
C.
D.
luteal period.
secretory phase.
menstrual period.
proliferative phase.
OVER
- 21 -
Use the following graph to answer question 50.
Uterine Cycle
thickness of
endometrium
1
3
5
7
9
11
13
15
17
19
21
23
25
27
days
50. The increased production of what hormone causes the change shown in the graph on or
about day 5?
A.
B.
C.
D.
estrogen
oxytocin
progesterone
luteinizing hormone (LH)
This is the end of the multiple-choice section.
Answer the remaining questions directly in this examination booklet.
- 22 -
PART B: WRITTEN RESPONSE
Value: 50 marks
Suggested Time: 75 minutes
INSTRUCTIONS: 1. Use a pen for this part of the examination unless otherwise instructed.
2. Write your answers in the space below the questions.
3. Organization and planning space has been incorporated into the space allowed
for answering each question.
4. You may not need all of the space provided to answer each question.
Use the following diagrams to answer question 1.
Cell A
Cell B
1. Cell A is found lining the proximal convoluted tubule of the nephron. Cell B is found in
the liver. Identify three visible differences between the two cells and explain how each
difference aids the cell in carrying out its specific functions.
(6 marks: 2 marks each)
Difference 1:
Explanation:
Difference 2:
Explanation:
Difference 3:
Explanation:
OVER
- 23 -
2. Levels of protein structure differ according to the types of bonds that hold them together.
As an enzyme is synthesized, these bonds form to give the protein its final 3-dimensional
shape. For each of the following diagrams, name the level of protein structure and describe
the type of bonding responsible.
(6 marks: 1 mark each for level; 1 mark each for description)
N
C
N
C
O
H
N
H
C
C
C
C
C
C
O
O
H
N
O
H
C
N
O
H
C
C
C
O
H
H
C
O
C
C
N
N
O
O
N
C
C
O
H
N
C C
C
C
N
C
N
N
C
N
C
O
Level of protein structure:
Description of bonding:
Level of protein structure:
Description of bonding:
- 24 -
H
O
R
N
H
C
H
C
R
C
O
C
R
N
H
N
H
H
O
C
C
Level of protein structure:
Description of bonding:
OVER
- 25 -
3. What effect would each of the following changes have on the rate of an enzyme-catalyzed
reaction occurring in the stomach? Give an explanation for the effect.
a) The temperature is increased from 35° C to 37°C .
(2 marks)
b) A competitive inhibitor is added.
(2 marks)
c) The pH is increased from 3 to 8.
(2 marks)
- 26 -
4. Identify four substances produced by the pancreas and give one function of each.
(8 marks: 1 mark each for substance; 1 mark each for function)
Substance 1:
Function:
Substance 2:
Function:
Substance 3:
Function:
Substance 4:
Function:
OVER
- 27 -
5. a) The average resting blood pressures and blood velocities were measured in various blood
vessels of an individual as shown in the table below. Identify the type of blood vessel in
the space provided.
(5 marks)
AVERAGE
BLOOD
VELOCITY
AVERAGE
BLOOD
PRESSURE
(cm/s)
(mm Hg)
A
48.0
100
B
0.5
22
C
15.0
60
D
25.0
2
E
4.0
10
BLOOD
VESSEL
TYPE OF
BLOOD VESSEL
b) Explain the observed blood pressure and velocity in the following vessels.
Vessel A:
(2 marks)
Vessel B:
(2 marks)
c) How does the sympathetic nervous system raise blood pressure?
- 28 -
(1 mark)
6. a) During external respiration, reactions involving gases occur in the capillaries.
Describe three of these reactions.
(3 marks)
i)
ii)
iii)
b) Describe two conditions in the capillaries during external respiration that affect the rate of
the reactions above.
(2 marks)
i)
ii)
OVER
- 29 -
Use the following diagram to answer question 7.
7. a) Label the diagram above using the numbers of the terms listed below.
(Not all the terms will be used.)
(2 marks:
1.
2.
3.
4.
5.
6.
1
2
mark each )
axon
dendrite
synapse
node of Ranvier
cell body
receptor
b) Describe how a reflex arc functions.
(5 marks)
- 30 -
8. Name two substances that are actively excreted during the process of tubular excretion.
(2 marks)
i)
ii)
END OF EXAMINATION
- 31 -