B3 LPP Content Describe Edward Jenner’s contribution to the development of vaccines Explain the process of immunisation Topic 1 –Control systems Explain of the advantages and risks associated with immunisation Describe the role of memory lymphocytes in secondary responses to antigen Describe the production of monoclonal antibodies Describe the use of monoclonal antibodies Describe how the exponential growth of a population of bacteria can lead to rapid development of an infection Describe Louis Pasteur’s contribution to the development of aseptic techniques Investigate the conditions affecting growth of micro-organisms (using resazurin dye) Describe how plants defend themselves against attack from pests and pathogens by producing chemicals Describe the impact that attack by pests and pathogens on plants has on human food supply Explain the importance of photoperiodicity in plants Describe the use of circadian rhythms in living organisms Topic 3 – Behaviour Topic 2 – Kidney and menstrual cycle Recall that cell metabolism leads to the build-up of waste products in the blood, including carbon dioxide and urea Recall that urea is produced from the breakdown of excess amino acids in the liver and is removed by the kidneys Describe the structure of the urinary system Describe possible treatments for kidney failure, including kidney dialysis and organ donation Describe the structure of a nephron Explain how the structure of the nephron is related to its function in filtering the blood and forming urine Describe the role of ADH (produced by the pituitary gland) in regulating the water content of the blood Explain how ADH production is controlled by a negative feedback mechanism Describe the stages of the menstrual cycle including menstruation, uterus lining thickening and ovulation Explain why the uterus lining is maintained if fertilisation occurs Explain how oestrogen, progesterone, FSH and LH control the menstrual cycle Explain how the structure of an egg is adapted to its function Explain how the structure of a sperm cell is adapted to its function, Evaluate the advantages and disadvantages of infertility treatments Recall that the sex of a person is controlled by one pair of chromosomes, XX in a female and XY in a male Explain how the sex of offspring is determined at fertilisation, using a genetic diagram Explain (using probabilities, ratios and percentages) how sex-linked genetic disorders are inherited Describe that sexual reproduction requires the finding and selection of a suitable mate Describe how animals have different mating strategies Describe that some animals, in particular birds and mammals, have developed special behaviours for rearing their young Explain why parental care can be a successful evolutionary strategy Explain how, within the animal kingdom, parental care may involve risks to the parents Describe the different behaviours exhibited by animals Explain how humans can make use of conditioning when training captive animals for specific purposes Design an experiment Investigate animal behaviour using choice chambers Describe how some animal behaviour requires communication Topic 4 – Communication and evolution Explain how animals use a variety of types of signals to communicate Describe the finding of the work of ethologists Describe how plants can communicate using chemicals, including with animals (particularly insects) and with other plants Using a range of examples explain how plants have co-evolved over time Describe the evidence for human evolution, based on fossils including Ardi, Lucy and Leakey’s discovery Describe the evidence for human evolution based on stone tools Describe why mitochondrial DNA provides evidence for the African Eve theory for non-Africans Explain why mitochondrial DNA is more useful than nuclear DNA for tracking human migration and evolution Suggest why the impact of climate change changed human behaviour Evaluate the evidence that we have for human migration Topic 6 – Enzyme technology Topic 5 – Biotechnology Describe biotechnology as the use of biological molecules to provide goods and services Describe the use of fermenters in large scale production Explain the need to supply suitable conditions in fermenters, and the effect they have on growth rates Design an experiment to Investigate the effect of factors on the growth of yeast Explain the advantages of using micro-organisms for food production Describe how mycoprotein is manufactured, including the role of the fungus Fusarium sp Explain the advantages of using mycoprotein as a food source Describe how bacteria are used in the production of yogurt from milk by the conversion of lactose to lactic acid Design and experiment to Investigate the effect of different factors on yogurt making Describe the use of enzyme technology in chymosin, invertase and washing powders Design an experiment to investigate the use of immobilised lactase to produce lactose free milk Explain recombinant DNA technology using insulin Explain the impact of human population growth on global food security Explain how Agrobacterium tumefaciens is used as a vector in creating transgenic plants Explain how Agrobacterium tumefaciens is used as a vector in creating transgenic plants Evaluate the advantages and disadvantages of introducing genes for insect resistance from Bacillus thuringiensis into crop plants Evaluate the costs and benefits of genetic modification of crop plants Explain the processes humans use to increase food production Evaluate of the advantages and disadvantages of replacing fossil fuels with biofuels
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