DNA structure II • • • • • DNA Composition of DNA Evidence for genetic material Structure Implications of the structure DNA & Nucleotides DNA and RNA nucleotides Evidence for genetic material: Griffith transformation Evidence for genetic material:Avery Hershey- Chase expt Structure Base Pairing Rules Watson-Crick Model Structure • • • • • The double helix base pairing rules anti-parallel strands bases/turn major and minor groove Models B= low salt A= high salt Z DNA= left, 12 bases/turn B-DNA A-DNA Z-DNA Properties of DNA Implications of the structure • DNA replication • Genetic Information stored in DNA molecule
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