Acronym: 3DMinBrain
Title: High-Throughput, High-Content Screening of human neuroectodermal organoids for
innovative drug discovery in neurodegenerative diseases
Coordinator:
Jean-Philippe Deslys, Commissariat à l'energie Atomique, Fontenay-aux-Roses,
France
Partners:
Name
Peter Heutink
Jean-Charles
Lambert
Giuseppe Legname
Institution
Deutsches Zentrum für Neurodegenerative
Erkrankungen Tübingen
Country
Institut Pasteur de Lille
Scuola Internazionale Superiore di Studi AvanzatiSISSA Trieste
France
Germany
Italy
Acronym: 3DPD
Title Advanced modelling of Parkinson’s disease with three-dimensional human midbrain
organoids:
Coordinator:
Jens Schwambor University of Luxembourg, Esch-sur-Alzette, Luxembour
Partners:
Name
Hans Schoeler
Peter Ertl
Vincenzo Bonifati
Dror Seliktar
Institution
Max-Planck-Institute for Molecular Biomedicine
Muenster
AIT Austrian Institute of Technology Vienna
Erasmus MC Rotterdam
Technion Haifa
Country
Germany
Austria
Netherlands
Israel
2
Acronym: ADAGE
Title: Alzheimer's Disease pathology within the ageing physiology
Coordinator:
Claudio Franceschi, IRCCS Institute of Neurological Sciences of Bologna, Italy
Partners:
Name
Nancy Pedersen
Kevin Mills
Giorgio Giaccone
Institution
Karolinska Institute Stockholm
London University College
Istituto Nazionale Neurologico Carlo Besta Milan
Country
Sweden
United Kingdom
Italy
3
Acronym: aSynProtec
Title: Alpha-synuclein pathology propagation in Parkinson’s disease and quest for novel
protective strategies
Coordinator:
Jia-Yi Li, Lund University, Sweden
Partners:
Name
Tiago Fleming
Outeiro
Olaf Riess
Pekka Kallunki
Daniel Otzen
Richard WadeMartins
Hilal Lashuel
Jeroen Raes
Institution
Country
University Medical Center Goetingen
University of Tuebingen
H. Lundbeck A/S
Aarhus University
Germany
Germany
Denmark
Denmark
University of Oxford
Swiss Federal Institute of Technology Lausanne
Leuven University
United Kingdom
Switzerland
Belgium
4
Acronym: BRIDGET
Title: BRain Imaging, cognition, Dementia and next generation GEenomics: a Transdisciplinary
approach to search for risk and protective factors of neurodegenerative disease
Coordinator: Stéphanie Debette, University of Bordeaux, France
Partners:
Name
Helena Schmidt
Tomi Pastinen
Hans J Grabe
M.A. Ikram
Ian Deary
Gunter Schumann
Perminder Sachdev
Institution
Medical University Graz
McGill Genome Center Montréal
Medical University of Greifswald
Erasmus MC University Medical Center
University of Edinburgh
King’s College, London
University of New South Wales
Country
Austria
Canada
Germany
Netherlands
United Kingdom
United Kingdom
Australia
5
Acronym: CircProt
Title: Synaptic CIRCuit PROTection in AD and HD: BDNF/TrkB and Arc signaling as rescue
factors
Coordinator:
Volkmar Lessmann, Otto-von-Guericke-University, Magdeburg, Germany
Partners:
Name
Eero Castren
Hélène Marie
Clive Bramham
Frédéric Saudou
Kurt Gottmann
Michele Migliore
Elena Cattaneo
Institution
University of Helsinki
CNRS Valbonne
University of Bergen
Inserm U836
Heinrich-Heine-University Duesseldorf
National Research Council
University of Milano
Country
Finland
France
Norway
France
Germany
Italy
Italy
6
Acronym: CureALS
Title: Stress granules and proteostasis in motor neurons: towards a mechanistic
understanding of ALS
Coordinator:
Simon Alberti, Max Planck Society, Dresden, Germany
Partners:
Name
Daniel Kaganovich
Serena Carra
Angelo Poletti
Nico Dantuma
Jared Sterneckert
Institution
Hebrew University of Jerusalem
Università degli Studi di Modena e Reggio Emilia
Modena
Universita' degli studi di Milano
Karolinska Institutet Stockholm
Technische Universität Dresden
Country
Israel
Italy
Italy
Sweden
Germany
7
Acronym: DACAPO-AD
Title: Deciphering Interactions of Acquired Risk Factors and ApoE-mediated Pathways in
Alzheimer's Disease
Coordinator:
Gabor Petzold, German Center for Neurodegenerative Diseases (DZNE), Bonn,
Germany
Partners:
Name
Maiken Nedergaard
Michael Heneka
Christian Göritz
Stephane Oliet
Institution
University of Copenhagen
University of Bonn
Karolinska Institutet
Inserm U862
Country
Denmark
Germany
Sweden
France
8
Acronym: EADB
Title: European DNA bank to decipher the Alzheimer disease missing heritability
Coordinator:
Jean-Charles Lambert, Institut Pasteur de Lille, France
Partners:
Name
Mikko Hiltunen
Alfredo Ramirez
Giacomina Rossi
Wiesje van der Flier
Martin Ingelsson
Rebecca Sims
Franck Jessen
Institution
University of Eastern Finland
Rheinische-Friedrich-Wilhelms-Universität Bonn
Foundation Carlo Besta Neurological Institute
VU University Medical Center
Upsalla University
Cardiff University
University Hospital Cologne
Country
Finland
Germany
Italy
Netherlands
Sweden
United Kingdom
Germany
9
Acronym: EPI-AD
Title: Targeting epigenetic dysregulation in the brainstem in Alzheimer’s Disease
Coordinator:
Daniel van den Hove, Maastricht University, Netherlands
Partners:
Name
Katie Lunnon
Thomas Haaf
Alfredo Ramirez
Antonio Del Sol
Institution
University of Exeter Medical School
University of Würzburg
Rheinische-Friedrich-Wilhelms-Universität Bonn
Luxembourg Centre for Systems Biomedicine
Country
United Kingdom
Germany
Germany
Luxembourg
10
Acronym: ESMI
Title: European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative
Coordinator:
Thomas Klockgether, Deutsches Zentrum für Neurodegenerative Erkrankungen
e.V. (DZNE), Bonn, Germany
Partners:
Name
Paola Giunti
Manuela Lima
Luis Pereira de
Almeida
Olaf Rieß
Bart P.C. van de
Warrenburg
Institution
University College London (UCL)
University of the Azores Ponta Delgada
Country
United Kingdom
Portugal
University of Coimbra
University of Tübingen
Portugal
Germany
Radboud University Medical Center Nijmegen
Netherlands
11
Acronym: GBA-PARK
Title: GBA1 mutations in Parkinson’s disease: clinical and biochemical prodrome, risk profile
and pathogenetic modelling for therapeutic intervention.
Coordinator:
Anthony Schapira, University College London, United Kingdom
Partners:
Name
Fabio Blandini
Paolo Ciana
Donato DiMonte
David Park
Institution
IRCCS C. Mondino National Neurological Institute Pavia
University of Milan
Deutsches Zentrum für Neurodegenerative
Erkrankungen (DZNE) Bonn
University of Ottawa
Country
Italy
Italy
Germany
Canada
12
Acronym: INSTALZ
Title: Genomic Instability in Alzheimer’s Disease and Related Disorders: a Single-Cell
Approach
Coordinator:
Bart Dermaut, Université de Lille, France
Partners:
Name
Institution
Country
Marie-Christine
Galas
Thierry Voet
Bart De Strooper
Vilhelm Bohr
Joakim Lundeberg
Inserm Lille Hinxton
Sanger Institute
KU Leuven
Copenhagen University
The Royal Institute of Technology Stockholm
France
United Kingdom
Belgium
Denmark
Sweden
13
Acronym: MADGIC
Title: Generation of Improved cellular and animal Models for identification of disease
phenotype and new therapeutic targets of Alzheimer’s Disease
Coordinator:
Jari Koistinaho, University of Eastern Finland /Itä-Suomen yliopisto, Kuopio,
Finland
Partners:
Name
Laurent Roybon
Gunnar Gouras
Claire Rampon
Dora Brites
Michael Heneka
Frank Edenhofer
Tarja Malm
Institution
Lund University
Lund University
University of Toulouse
Universidade de Lisboa
University Hospital of Bonn
Julius-Maximilians-University of Würzburg
University of Eastern Finland Kuopio
Country
Sweden
Sweden
France
Portugal
Germany
Germany
Finland
14
Acronym: ModelPolyQ
Title: Advanced models of polyglutamine disorders (HD, SCA2, SCA3, SCA7)
Coordinator:
Luis Pereira de Almeida, CNC- Center for Neuroscience and Cell Biology of
Coimbra, Portugal
Partners:
Name
Huu Phuc Nguyen
Yvon Trottier
Nicole Déglon
Anselme Perrier
Elena Cattaneo
Institution
University of Tuebingen
IGBMC/CNRS/INSERM/Unistra Illkirch
Lausanne University Hospital (CHUV)
Inserm/UEVE U861 Evry
University of Milan
Country
Germany
France
Switzerland
France
Italy
15
Acronym: NAB3
Title: Development of a Novel Multicellular In Vitro Model of Alzheimer’s disease-like BloodBrain Barrier
Coordinator:
Francesca Re, University of Milano-Bicocca (UNIMIB), Monza, Italy
Partners:
Name
Claudia G. Almeida
Thomas Ohm
Wiep Scheper
Institution
Faculdade de Ciencias Medicas da Universidade de
Lisboa
Charité Universitätsmedizin Berlin
Stichting VU-VUmc Amsterdam
Country
Portugal
Germany
Netherlands
16
Acronym: PROP-AD
Title: Propagation behaviour of peripheral amyloid-beta towards brain structures: effects of the
blood-brain barrier
Coordinator:
Jens Pahnke, University of Oslo, Norway
Partners:
Name
Claus Pietrzik
Dan Frenkel
Henrik Lalowski
Maciej BiIverstål
Institution
University of Mainz
University of Tel Aviv
Karolinska Institutet Stockholm
University of Helsinki
Country
Germany
Israel
Sweden
Finland
17
Acronym: REfrAME
Title: Pathway complexities of protein misfolding in neurodegenerative diseases: a novel
approach to risks evaluation and model development
Coordinator:
Giuseppe Legname, Scuola Internazionale Superiore di Studi Avanzati-SISSA,
Trieste, Italy
Partners:
Name
Giuseppe Di Fede
Mathias Jucker
Michel Goedert
Jia-Yi Li
Adriano Aguzzi
Michal Novak
Institution
Fondazione IRCCS Istituto Neurologico Carlo Besta
Milano
German Center for Neurodegenerative Diseases DZNE
Tübingen
Medical Research Council Cambridge
Lund University
University of Zurich (UZH)
Slovak Academy of Sciences (SAS) Bratislava
Country
Italy
Germany
United Kingdom
Sweden
Switzerland
Slovakia
18
Acronym: SNOWBALL
Title: Cerebral amyloid angiopathy and vascular dementia
Coordinator:
Marc Fatar, University of Heidelberg, Mannheim, Germany
Partners:
Name
Institution
Country
Laurance FenartTilloy
Rick M. Dijkhuizen
Klaus Fassbender
Mar HernándezGuillamon
Universite D´Artois
University Medical Center Utrecht
Saarland University
France
Netherlands
Germany
Hospital Universitari Vall D'Hebron
Spain
19
Acronym: STAD
Title: Synapse-to-nucleus communication in Alzheimer's disease
Coordinator:
Monica DiLuca, Università degli Studi di Milano, Italy
Partners:
Name
Christophe Mulle
Michael R. Kreutz
Institution
Centre National de la Recherche Scientifique Bordeaux
Leibniz Institute for Neurobiology
Country
France
Germany
20
Acronym: SYNACTION
Title: Unravelling the pathophysiological role of alpha-synuclein aggregation, transmission and
neuroinflammation in neurodegeneration
Coordinator:
Veerle Baekelandt, Katholieke Universiteit Leuven, Belgium
Partners:
Name
Ronald Melki
Michael Heneka
Stéphane Hunot
Institution
Centre National de la Recherche Scientifique Gif sur
Yvette
Universitaetsklinikum Bonn
Institut du Cerveau et de la Moelle Epiniere Paris
Country
France
Germany
France
21