PROBIOTICS JUST
GOT SMART
Content:
1. Background
3.3.2 Boosted immune system
1.1 What is the human microbiota?
3.3.3 Enhanced cancer defenses
1.2 How do microorganisms affect the body?
3.3.4 Allergy prevention
1.3 What are the main types of bacteria which
affect the body?
2. Dysbacteriosis: microbial imbalance
2.1 What is dysbacteriosis?
2.2 How does dysbacteriosis affect the body?
3.4 Other benefits of probiotics
4. Bio-In
4.1 Standard probiotics: some problems
4.2 Bio-In’s distinguishing features
4.2.1 The Synbiotic system
4.2.2 Individually personalized
3. Probiotics
3.1 How is microbial balance restored?
3.2 What are probiotics and how do they work?
3.3 What are the key benefits of probiotics
3.3.1 Anti-aging
4.2.3 Carefully balanced
4.2.4 Guaranteed effectiveness
5. User testimonials
1.1 What is the human microbiota?
The term microbiota refers to all the microorganisms living in the human body.
Elementary microorganisms outnumber our own body cells by at least 10 to 1, while
the total number of microbial genes outnumber the total number of human genes by
100 to 1.
1
99
This means that 99% of the genetic code in your body is not yours. It actually belongs
to microorganisms.
1.2 How do microorganisms affect the body?
Microorganisms significantly impact a range of health and wellbeing
factors.
These include:
1 Early aging
5 Digestion
2 Appearance
6 Allergies
3 Immunity
7 Emotional well-being
4
Carcinogens
1.2 How do microorganisms affect the body?
Bacteria are both the most numerous and the most impacting
microorganisms living in the human body.
The highest concentrations of bacteria are found in the stomach, the
intestines and the vagina, on the skin, and around the rectum.
Bacteria also thrive in the mouth, within the oral cavity (the airways),
in the joints, inside the urinary tract and in many other locations.
1.3 What are the main types of bacteria which
affect the body?
1. Good bacteria
(probiotics).
Probiotic strains affect our
body in many positive
ways. They can be found in
the digestive tract, on the
skin, and in our airways.
2. Pathogenic bacteria.
These are disease-producing
microorganisms. They are
the cause of a number of
complaints which include
early aging, dermatitis,
digestive problems, allergies
and carcinogens.
3. Opportunistic
pathogenic bacteria.
These are the natural
occupants of various
parts of the body. They
cause diseases when
host defenses suddenly
drop.
2.1 What is dysbacteriosis?
An imbalance in intestinal microorganisms
(microflora) is called dysbacteriosis.
Dysbacteriosis is when the number of good bacteria
decreases while the number of pathogenic ones
increases.
It can be caused by:
stress
an unhealthy diet
diarrhea or chronic constipation
antibiotics and other pharmaceutical products
-
low levels of physical activity
2.1 What is dysbacteriosis?
1
Common symptoms of
dysbacteriosis:
1
Fatigue, depression
2
Halitosis
3
Abdominal swelling
4
Nausea and occasional vomiting
5
Stomach discomfort or pain
6
Excess of intestinal gas
7
Constipation or diarrhea
2
4
3
5
6
7
2.2 How does dysbacteriosis affect my body?
1. Poorer digestion and
metabolism:
 Poor absorption of
nutrients
 Development of obesity
 Leaky gut syndrome,
resulting in food
intolerances and pain
 Increased level of free
radicals and toxins
 Lack of vitality in skin
and hair
2. Weakened immune
system:
3. Associated
Conditions:
 Allergic reactions
 Early aging
 Increased carcinogenic
damage to cells
 Chronic fatigue syndrome
 Chronic inflammation of
both organs and tissue
 Weakening of other
protective systems
(endocrine, nervous)
 Psychological conditions
including depression
 Type 2 Diabetes
 Increased risk of
cardiovascular diseases
(i.e. atherosclerosis)
3.1 How is microbial balance restored?
Microbial balance is
achieved by restoring the
perfect good bacteria to bad
bacteria ratio.
20%
Bad bacteria
80%
Good bacteria
3.2 What are probiotics and how do they work?
Probiotics are the living microorganisms that have a healthy effect on the human body
when taken in the right doses.*
When probiotics are introduced into the digestive system, they compete with
pathogenic bacteria, and by doing this, restore the balance of good to bad bacteria.
Probiotics
80%
Bad bacteria
*official definition of probiotics by World Health Organization and Food and
Agriculture Organization
80%
Good bacteria
3.3 What are the key benefits of probiotics?
Probiotics restore the balance of
microorganisms in the body. This helps
to:
- prevent early aging
- boost the immune system
- enhance cancer defenses
- reduce allergic reactions
3.3.1 Anti-aging
Early aging is caused by toxins and free
radicals in the body.
It also occurs when the body does not receive
enough vitamins, minerals and
antioxidants.
According to scientific research, good
bacteria in the gut destroy the toxins and
free radicals that cause early aging.
Probiotics also help the body to digest and
absorb nutrients from food. As a result, the
body receives more of the antioxidants,
vitamins and minerals it requires to
maintain optimum health.
3.3.1 Anti-aging
Probiotics enable organic chemicals called polyphenols to be absorbed by cells in
the digestive system. Polyphenols activate telomerase, enzymes that are able to restore
the cells’ telomeres, thus protecting genetic material from destruction and early aging.*
*Wang XB, Zhu L, Huang J, Yin YG, Kong XQ, Rong QF, Shi AW, Cao KJ.Resveratrol-induced augmentation of telomerase activity
delays senescence of endothelial progenitor cells. Chin Med J (Engl). 2011 Dec;124(24):4310-5.
3.3.1 Anti-aging
Telomere damage is also caused by psychological stress.
Probiotics produce various anti-stress compounds such as
dopamine and serotonin which:
- reduce levels of stress hormones like cortisol, preventing damage to cells and
reducing aging;
- enhance emotional well being;
- alleviate depression and anxiety;
- increase brain performance, cognitive functions, and memory*
*Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF. Ingestion of
Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve.
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5.
3.3.1 Anti-aging
The damage to DNA that leads to
premature aging is also caused by free
radicals.
Probiotics strengthen the natural
antioxidants in the body which capture
and neutralize free radicals.*
This prevents DNA damage and slows down
the aging processes.
*Lutgendorff F, Trulsson LM, van Minnen LP, Rijkers GT,
Timmerman HM, Franzén LE, Gooszen HG, Akkermans LM,
Söderholm JD, Sandström PA. Probiotics enhance pancreatic
glutathione biosynthesis and reduce oxidative stress in
experimental acute pancreatitis. Am J Physiol Gastrointest Liver
Physiol. 2008 Nov;295(5):G1111-21.
3.3.2 Boosted immune system
Probiotics benefit the immune system
in a number of ways:
1) They create a barrier in the gut that prevents
malicious bacteria from penetrating into the
blood stream.
2) They stimulate the production of protective
mucous in the gut.
3) They train the bodies immune cells.
4) They suppress inflammatory reactions.
3.3.2 Boosted immune system
Training the immune cells
The contact of the gut’s epithelium with bacteria
stimulates the production of immune cells, which
then spread through the entire body.
The good bacteria cells train and activate
immune cells to recognize and destroy
pathogens.
The immune system is tightly connected with
other important bodily systems like the
endocrine system. So, strengthening the immune
system affects other physiological processes and
improves general health.
3.3.3 Enhanced cancer defenses
Cancer is the rapid and uncontrollable emergence and reproduction of mutated cells.
Cancer has a number of causes:
Mutation of human cells when transmission of genetic
information fails.
Impact of free radicals on cell metabolism.
Impact of external factors like tobacco smoke, pesticides, bacterial
toxins, alcohol and UV radiation.
3.3.3 Enhanced cancer defenses
Good bacteria help protect the body against cancer
1) They destroy
carcinogens
(cancer causing
agents) before
they can cause
harm, and reduce
their activity in the
digestive tract.
2) They protect the
DNA from free
radicals that cause
cell mutations.
3) They produce
fatty acids and
vitamins B7, B9,
B12, and K, all of
which protect
genetic material
and reduce the
risk of mutations
that cause cancer.
4) They help to
regulate the
growth of
proliferating
cells to prevent
cancerous tissue
development.
3.3.4 Allergy prevention
Allergies are improper reaction to certain compounds that are actually safe, and are
caused by failures in the immune system.
The World
Health
Organization has
identified
allergies as the
largest epidemic
disease in
children.
25% of people
are susceptible
to allergies.
In the last
20 years, the
number of
asthmatics in the
world has
increased
by 160%.
3.3.4 Allergy prevention
Allergies and probiotics
Scientists have proved that there is a direct link
between allergies and the balance of bacteria in
the intestines.
People with low levels of good bacteria - like
Bifidobacterium and Lactabacillus - and high
levels of pathogenic bacteria are more likely to
suffer from allergic reactions.
By improving the ratio of good bacteria to
pathogenic bacteria, probiotics reduce the
likelihood of allergic reactions.
3.4 Other benefits of probiotics
1. Normalized digestion
2. Improved metabolism
Probiotics:
Probiotics:
 release agents that fight
pathogenic bacteria;
 produce vitamins (В7, В9,
В12, К);
 normalize intestinal gas
production;
 protect from free radicals;
 prevent obesity.
 prevent cardiovascular
diseases.
4.1 Standard probiotics: some problems
Many standard probiotic products suffer from three main defects:
Up to 75% of probiotic
cultures die before the
packet is opened.
Many probiotics are susceptible
to attack by saliva and stomach
acid, rendering them
ineffective.
Up to 60% of probiotics
fail to establish
themselves inside the
digestive system and are
flushed out.
4.2 Bio-In’s distinguishing features
The key strengths of Bio-In are that;
It is a Synbiotic system
Each program
is individually personalized
We guarantee the
effectiveness our
probiotics
4.2.1 The Synbiotic system
A Synbiotic system is one which contains a fusion of three essential elements.
These are:
PROBIOTICS
living friendly bacteria
COBIOTICS
special nutrients that
provide nutrition both to
the human cells and the
resident probiotics
PREBIOTICS
non-digestible sugars*
that feed the probiotics
* non-digestible sugars – they cannot be digested by human enzymes and absorbed in the small intestine.
Therefore they are able to reach the colon and nourish probiotics, strengthening their reproduction.
4.2.1 The Synbiotic system
Bio-In contains 14 patented probiotic strains, along with prebiotics, antioxidants,
herbal extracts, vitamins, minerals and cobiotics.
There are 1.5 trillion living cultures of the following probiotic stains in every
program:
Lactobacillus
Lactococcus
Bifidobacterium
Streptococcus
4.2.1 The Synbiotic system
The Bio-In systems works just like planting a seed:
The first Digestico stage prepares
the ground, removing weeds and
loosening the soil.
Probiotics are the seeds
themselves.
Prebiotics and cobiotics act like water
and sunlight, nourishing and hydrating
the seeds, guaranteeing their healthy
growth and continued harvest.
4.2.2 Individually personalized
Every 120 day Bio-In program is
individually tailored to meet the
needs of each user.
4.2.2 Individually personalized
Bio-In users receive:
An individually tailored
program.
A personal detoxification
plan and nutritional
recommendations.
A Quality of Life Coach that
provides assistance and
guidance during and after
the Bio-In program.
4.2.3 Carefully balanced
The 120 day program consists of 8 stages. The first stage cleanses and
prepares the intestinal system, while the next six stages are designed to
guarantee that our probiotics are able to establish
themselves and thrive. The final stage is specifically engineered to
maximize Bio-In’s effectiveness.
Day
1
9
21
9
21
9
21
9
21
Day
120
4.2.4 Guaranteed effectiveness
Bio-In is currently the only company to
guarantee that all the living probiotics in
each sachet remain alive until the
product expiration date
Bio-In utilises state-of-the-art packaging
which guarantees that the probiotics
retain their vital capacity at room
temperature
5. User testimonials
Svetlana Efimova
Solvita Gutmane
Isak Levi
The Bio-In program helped me
increase my self-discipline and
helped me lose weight. I also really
liked that it was divided into stages as
this helped me to keep track of my
progress, and see how the program
was improving my body.
The program inspired me to stay healthy
and exercise regularly; it also helped me to
transform my diet for the better. I now feel
that my quality of life has really been
improved, and look forward to following the
program again with my daughter!
My body now functions much better.
They say perfection knows no limits,
but I still think that with Bio-In you
can reach them!