ICSC 0405 - CAFFEINE
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[ EN - FI - HU ]
CAFFEINE
ICSC: 0405
Peer-Review Status: 27.03.1998 Validated
1,3,7-Trimethylxanthine
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Methyltheobromine
Methyltheophylline
CAS #: 58-08-2 RTECS #:
EV6475000
UN #: 1544
EC #: 613-086-00-5
EINECS #: 200-362-1
Formula: C8H10N4O2
Molecular mass: 194.19
TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE
Combustible. Gives off irritating or toxic
fumes (or gases) in a fire.
NO open flames.
Use water spray, powder.
EXPLOSION
PREVENT
DISPERSION OF
DUST!
EXPOSURE
See Ingestion.
Use local exhaust Fresh air, rest. Refer for medical
or breathing
attention.
protection.
Inhalation
Skin
Eyes
Ingestion
Headache. Dizziness. Abdominal
cramps. Nausea. Vomiting. Convulsions.
Tremor.
SPILLAGE DISPOSAL
Protective
gloves.
Remove contaminated clothes.
Rinse skin with plenty of water or
shower.
Wear safety
spectacles.
First rinse with plenty of water for
several minutes (remove contact
lenses if easily possible), then refer
for medical attention.
Do not eat, drink,
or smoke during
work.
Rinse mouth. Give a slurry of
activated charcoal in water to drink.
Induce vomiting (ONLY IN
CONSCIOUS PERSONS!). Refer
for medical attention .
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted
to the airborne concentration of the substance. Sweep
spilled substance into covered sealable containers. If
appropriate, moisten first to prevent dusting. Carefully
collect remainder. Then store and dispose of according
to local regulations.
Do not transport with food and feedstuffs.
EC Classification
Symbol: Xn; R: 22; S: (2)
UN Classification
UN Hazard Class: 6.1
GHS Classification
EMERGENCY RESPONSE
SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-III.
Separated from food and feedstuffs. Well closed.
IMPORTANT DATA
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ICSC 0405 - CAFFEINE
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Physical State; Appearance
ODOURLESS WHITE CRYSTALS OR CRYSTALLINE
POWDER.
Routes of exposure
The substance can be absorbed into the body by
inhalation and by ingestion.
Physical dangers
Inhalation risk
Evaporation at 20°C is negligible; a harmful
concentration of airborne particles can, however, be
reached quickly when dispersed.
Chemical dangers
Decomposes on burning. This produces toxic fumes
including nitrogen oxides.
Occupational exposure limits
TLV (NOT-ESTABLISHED):.
Effects of short-term exposure
The substance may cause effects on the central nervous
system and cardiovascular system. This may result in
insomnia, excitement, tachycardia and polyuria.
Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes
toxic effects upon human reproduction.
PHYSICAL PROPERTIES
ENVIRONMENTAL DATA
Sublimation point: 178°C
Melting point: 238°C
Density: 1.23 g/cm³
Solubility in water, g/100ml: 2.17
Octanol/water partition coefficient as log Pow: -0.07
NOTES
Card has been partly updated in October 2005.
See section Emergency Response.
ADDITIONAL INFORMATION
IPCS
International
Programme on
Chemical Safety
LEGAL NOTICE
Prepared in the context of cooperation between the International Programme on
Chemical Safety and the European Commission
© IPCS 2004-2012
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of
this information.
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2013-08-15