TEXAS A & M UNIVERSITY-CORPUS CHRISTI
Clinical Laboratory Science Program
BIMS 4378: ADVANCED MEDICAL MICROBIOLOGY
SYLLABUS (FALL 2009)
Instructor:
Dr. Lillian Waldbeser
Office:
CS 242
Office Hours: Tuesdays & Thursdays: 10:00 a.m. – 12:30 p.m.
Other days of the week: by appointment only
I am happy to see you outside my office hours. Making an
appointment would ensure my being in my office when you stop by.
Please use the student university email service to contact me.
Phone:
(361) 825-6050
E-mail:
[email protected]
COURSE DESCRIPTION
This course consists of lecture and laboratory instruction on parasites and fungi
that cause diseases in human, with emphasis on life cycle, identifying
characteristics and pathology.
STUDENT LEARNING OUTCOMES
Upon completion of this course the student will have a good understanding of and
will be able to perform, describe, or identify the following:
1. the procedures for recovery of parasites and fungi.
2. the type of culture media, and the reagents used in the identification of
parasites and fungi of medical importance.
3. the life cycles of the parasites and fungi of medical importance.
4. the pathological significance of human parasites and fungi.
5. the distinguishing characteristics of parasites of medical importance.
6. the distinguishing characteristics of nonpathogenic human parasites.
7. the distinguishing characteristics of fungi of medical importance.
8. the distinguishing characteristics of common saprophytic fungi.
The specific lecture and laboratory objectives are contained in the laboratory
manual. All examination questions are keyed to those objectives. The laboratory
exercises are structured to foster teamwork and cooperative learning.
Lab coats, gloves, long pants/skirts, and closed-toe/heel shoes are required for all
labs.
REQUIRED TEXT
1. Markell & Voge's Parasitology by John & Petri, 9th ed., Saunders.
F.A. Davis Co.
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2. Medical Mycology A Self-Instructional Txt by Kern & Blevins, 1997, 2nd ed.,
F.A. Davis Co.
3. Texas A&M-Corpus Christi Laboratory Manual
FURTHER READINGS
1. Medical Mycology by Kwong-Chung and Bennett, 1992, 1st ed., Lea & Febiger.
2. Parasitic Diseases by Despommier, Gwadz and Hotez, 1995, 3rd ed., SpringerVerlag.
GRADES
The final grade will be based on an accumulation of all points earned by the
following activities:
For undergraduate credits:
In addition to the examinations, the students will write a term paper. The term
paper will consist of a minimum of four typed pages on topics mutually agreed
upon between the instructor and the students. Each term paper will contain
information from a minimum of three research articles published in peer-reviewed
journals. Each paper will include a background of the topic including diagnostic
tests and treatments, the scientific data from the research articles, and a
conclusion that includes the students' critical evaluation of the articles.
ACTIVITIES
Exam I
Exam II
Exam III
Final Exam
Term paper
Attendance
Laboratory:
Worksheets/quizzes
Lab Unknown I
Lab Unknown II
Final Lab Unknown
Total points
POINTS
100
100
100
200
100
50
50
75
75
150
1000
The final exam will be comprehensive. Material in all lectures will be examined.
Laboratory worksheets should be turned in to the instructor the week following
the laboratory exercise. Term papers should be turned in a week before class
presentations. Work will not be accepted late and a zero will be given for the
assignment. Tests can only be taken during the scheduled time, except in cases of
extreme emergencies. Documented proof of emergencies is required.
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There will be quizzes given during the lectures or in the lab sessions. There will
be no make up for the quizzes.
*Students with a university approved scheduled absence (athletics, military
duty, etc.) MUST contact the lecture and lab instructor, well in advance of a
scheduled absence. Exams may be taken early in those specific cases.
Students who do not arrange to take exams ahead of time will not be eligible
for this special consideration. A written excuse from the university
department involved or the Office of the Dean of Students is required.
The following scale will be used to report grades:
A:
B:
C:
D:
F:
850 – 1000
750 - 849
650 - 749
500 - 649
Below 500
points
"
"
"
"
GRADE APPEALS
As stated in the Texas A&M University-Corpus Christi University Rules and
Procedures, a student who believes that he/she has not been held not to
appropriate academic standards as outlined in the class syllabus, equitable
evaluation procedures or appropriate grading, may appeal the final grade given in
the course. The burden of proof is on the student to demonstrate the
appropriateness of the appeal. A student with a complaint about a graded should
first discuss the matter with the instructor. Consult the University Rules and
Procedures for details of the appeal process. Students may also contact the Office
of Student Affairs for assistance and/or guidance in the grade appeal process.
HONESTY
The college catalog contains the university statement on academic integrity.
As stated in the University catalog, "University students are expected to conduct
themselves in accordance with the highest standards of academic honesty."
Cheating will not be tolerated and will result in a failing grade in the course and
possible further disciplinary action by the university.
ATTENDANCE
Class attendance is expected. If absent from class you will be responsible for
knowing the material covered. Students who register late must make up any work
they have missed during the first week. You are expected to know the material
covered in class and in the text book, and to turn in assignments on time. In case
of absence on test days, evidence that the absence was necessary will be required.
In the case of an extreme emergency causing an absence on major exam days,
evidence that the absence was necessary will be required
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DISABILITY AND VETERANCE SERVICES
“The Americans with Disabilities Act (ADA) is a federal anti-discrimination statute
that provides comprehensive civil rights protection for persons with disabilities.
Among other things, this legislation requires that all students with disabilities be
guaranteed a learning environment that provides for reasonable accommodation of
their disabilities. Texas A&M University-Corpus Christi is committed to provide
persons with disabilities an equal opportunity to access campus facilities,
resources, and programs. Support and accommodations are also available for
returning veterans who experience cognitive and/or physical access issues in the
classroom or on campus. If you need disability accommodations in this class,
please see me as soon as possible. If you suspect that you may have a disability
(physical impairment, learning disability, psychiatric disability, etc.), please
contact the Services for Students with Disabilities Office (located in Driftwood 101)
at 825-5816. It is important that you contact them in a timely fashion as it may
take several days to review requests and prepare accommodations. Please have
your accommodation letter and the necessary forms from Services for Students
with Disabilities Office with you when you come to see me.
My lectures will be posted on WebCT.
TO
-
ACCESS WEBCT:
Go to TAMUCC home page: http://www.tamucc.edu/
Select: The Island Online
Select: Students
Login to Island Online (WebCT)
Enter your WebCT ID and Password, which are the same as your campus
computer user ID and password.
If you have not applied for a computer user ID, go to the following website:
http://kestrel.tamucc.edu/~newuser
If you have any problems logging into WebCT with your new User ID, contact:
Collegis Helpdesk at:
1-877-725-4357.
-
After you have logged in, you can select the courses that you wish to browse.
e.g.
Fall 2008
BIMS 4378
Advanced Medical Microbiology
Instructor: Lillian Waldbeser
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TERM PAPER RUBRIC
The subjects can be of any of the topics covered in the lectures.
It is due on Wednesday, December 3, 2008.
The following guidelines are what I expect to be in your written paper:
1. At least four typed pages, 1.5 spaces.
2. At least four references, from journals not from text books nor
Websites.
3. Illustrations (sketches, diagrams, charts, etc.) included whenever
possible.
4. The paper should include:
a) Introduction: background information
b) Latest information on the topic: observations, experiments, diagrams
and charts, etc.
c) Summary and conclusion: include your own critique of the papers
as well as your thoughts on the topic.
The written paper will be graded according to the above criteria.
Suggested Topics for Term Paper
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
Pathogenesis of Entamoeba hystolytica
Dientamoeba fragilis: association with other parasites
Classification of Apicomplexa: fungi or protozoan?
The new species of Plasmodium (non-vivex; non-ovale; non-malariae; nonfalsiparum)
Epidemiology of Toxoplasma gondii
Malaria vaccines
Plasmodium falsiparum
Epidemiology of Pneumocystis carini
Antigenic variation in Typanosoma
Mechanism of Typanosoma induced sleeping sickness
Autoimmunity in Typanosoma cruzi infections
Hydatid disease
The free-living state of Strongyloides
Visceral larval migrants
Dimorphic fungi
Dermatophyte infections in cats and dogs
Mycetoma
Coccidiomycosis
Candidiasis
Penicillium infections
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TEXAS A & M UNIVERSITY-CORPUS CHRISTI
BIMS 4378: ADVANCED MEDICAL MICROBIOLOGYOLOGY
INSTRUCTOR: DR. LILLIAN WALDBESER
CS-115
MW 10:00 - 10:50 A.M.
LECTURE SCHEDULE (FALL 2009)
Wk Day Date
Lec
1
W
8/26
Lec 1
PROTOZOA:
Amoebae:
Entamoeba spp., Endolimax,
Iodamoeba, Naegleria, Acanthmoeba
2
M
8/31
Lec 2
Flagellates: Trichomonas, Enteromonas,
Rotortamonas, Chilomastix
W
9/02
Lec 3
Flagellates: Giardia, Dientamoeba
Cilliate: Balantidium
M
9/07
----
Labor Day Holiday
W
9/9
Lec 4
Apicomplexa:
M
9/14
Lec 5
Apicomplexa: MIcrosporidiaum, Toxoplasma
W
9/16
Lec 6
Apicomplexa: Plasmodium (Malaria)
M
9/21
Lec 7
Apicomplexa: Plasmodium
W
9/23
Lec 8
Babesia, Pneumocystis and Blastocystis
M
9/28
Lec 9
Blood and tissue dwelling Protozoa:
Hemoflagellates: Trypanosoma
Hemoflagellates: Leishmania
W
9/30
Lec 10
TREMATODES:
Intestinal flukes: Fasiolopsis, Echinostoma,
Heterophyes, Metagonimus
M
10/05 ----
EXAM I (Lec 1-9 material)
W
10/07
Lec 11
Liver flukes: Fasiola, Clonorchis, Opisthorchis
Lung fluke: Paragonimus
M
10/12
Lec 12
Blood flukes: Schistosomes
W
10/14
Lec 13
CESTODES: Diphyllobothrium, Hymenolepis,
Dipylidium
M
10/19
Lec 14
Cestodes: Taenia
W
10/21
Lec 15
Tissue cestodes: Hydatid Disease, Coenurosis,
Sparganosis
3
4
5
6
7
8
9
Subject
Cryptosporidium, Cyclospora,
Isospora, Sarcocystis
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TEXAS A & M UNIVERSITY-CORPUS CHRISTI
BIMS 4378: ADVANCED MEDICAL MICROBIOLOGYOLOGY
INSTRUCTOR: DR. LILLIAN WALDBESER
CS-115
MW 10:00 - 10:50 A.M.
LECTURE SCHEDULE
Wk Day Date
Lec
10
11
14
15
Subject
M
10/26
Lec 16
NEMATODES:
Intestinal Nematodes: Ascaris, Trichuris, Enterobius
W
10/28
Lec 17
Intestinal Nematodes: Hookworms, Strongyloides
M
11/02
Lec 18
Blood and tissue dwelling Nematodes:
Filarial Nematodes: Wuchereria, Brugia, Loa Loa
Mansonella, Onchocerca
W
11/04
Lec 19
Tissue Nematodes:
Cutaneous larval migrans, Visceral larval migrans,
Trichinella, Dracunculus, Angiostrongylus, Anisak
Dirofilaria
11/9
----
EXAM II (Lec 10-19 material)
W
11/11
Lec 20
Fungi characteristics
M
11/16
Lec 21
Dermatomycosis :
Superficial mycoses:
W
11/18
Lec 22
Subcutaneous mycoses:
Sporotrichosis
Phaeohyphomycosis, Mycetoma, Chromoblastomycosi
M
11/23
Lec 23
Systemic mycoses:
Coccidioidomycosis
Paracoccidioidomycosis, Blastomycosis, Histoplasmosis
W
11/25
Lec 24
Opportunistic Yeasts:
Cryptococcosis,
Geotrichosis, Candidiasis
M
11/30
Lec 25
Opportunistic infections:
Aspergillus, Penicillium,
Mucor, Rhizopus, Absidia
W
12/02
----
Review/Case Studies
Term paper due
12 M
13
(FALL 2009)
Dermatophytes
Piedra, Malassezia
16 M
12/07 ----
EXAM III (Lec 20-25 material)
17 W
12/16 ----
FINAL EXAM
8:00 am - 10:30 am
(Material from all lectures)
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TEXAS A & M UNIVERSITY-CORPUS CHRISTI
BIMS 4378: ADVANCED MEDICAL MICROBIOLOGYOLOGY
INSTRUCTOR: DR. LILLIAN WALDBESER
CS 231
W 5:30 - 8:25 P.M.
LABORATORY SCHEDULE
(FALL 2009)
Wk Day Date
Lab
Subject
1
W
8/26
Lab 1
Safety
Normal stool findings
2
W
9/02
Lab 2
Amoebae
3
W
9/09
4
W
9/16
Lab 3
Lab 4
Lab 5
Flagellates & Cilliates
Miscellaneous Apicomplexa
Malaria
5
W
9/23
Lab 6
Blood & tissue protozoans
6
W
9/30
----
Unknown I
7
W
10/07
Lab 7
Trematodes: Intestinal & liver
8
W
10/14
Lab 8
Trematodes: Lung & blood
9
W
10/21
Lab 9
Cestodes
10
W
10/28
Lab 10
Nematodes: Intestinal
11
W
11/04
Lab 11
Nematodes: Blood and tissue dwelling
12 W
11/11 ----
Unknown II
13
W
11/18
Lab 12
Mycological procedures
Characteristics of fungi
Dermatophytes
Agents of superficial mycosis
14
W
11/25
Lab 13
15
W
12/02
Lab 14
Dermatiacious fungi
Agents of systemic mycosis
Eumycotic mycetoma
Yeasts
Zygomycosis
Saprophytic fungi
16
W
12/9
----
Final Unknown
(Comprehensive Parasitology + Mycology)
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