Does Diet Affect Sleep or Does Sleep Affect Diet? Ruth Schneider, MPH, RD, LD, FAND September 2016 The Short Answer is… Yes! (but not much) Weight status • “Improvements in sleep duration have been observed with weight loss, and reduced weight status is associated with healthy changes in sleep patterns.” (Golem et.al.) • Numerous reviews and meta-analyses reporting an inverse relation between sleep duration and weight status have been published. • “A few studies reported U-shaped associations between sleep duration and weight status, indicating that too much sleep (>9 h/night) as well as too little sleep (<5 h/night) are associated with increased risk of over- weight status in adults.” (Golem, et.al.) Daytime sleepiness is associated with higher BMI (Grandner) Eating behaviors • Short-duration sleepers (< 6 hours) showed a distinct picture of eating characterized by skipping main meals and higher contributions of snacks; earlier and later eating episodes, and more beverages. However, total energy intake was very similar to normal duration sleepers. • In a study where sleep was actually restricted, this led to higher energy intake. (NHANES 2005-10) Eating behaviors “Difficulty maintaining sleep was associated with fewer foods in the diet and being on a special diet.” (Grandner) (not significant after adjustments) Many specific nutrients (viatmins D, B12, and folate, calcium, selenium) and fatty acids associated (positively and negatively) with sleep. (Grandner) However, it is difficult to translate this into specific recommendations, other than general good diet. Disease Risk • “In humans, partial sleep restriction alters sympathetic nervous system activity, impairs glucose tolerance, and alters hormonal levels.” “Inadequate sleep may be a risk factor for Type 2 Diabetes.” (Golem) • “Short sleep duration (<7 h/night) is associated with higher risk and incidence of cardiovascular disease and poor cardiovascular health outcomes, including hypertension, hypercholesterolemia, myocardial infarction, and cerebrovascular accident.” (Golem) • “Inadequate sleep also is associated with increased inflammation that overwhelms the immune and antioxidant systems within the body.” (Golem) • Adequate sleep patterns protect against obesity, dyslipidemia, diabetes and insulin resistance (study of 52 people) (Crispim) Possible mechanisms • From NHANES, 2007-08: Studies show that restricted sleep led to “changes in appetite-regulating hormones, specifically lower levels of leptin [a satiety signal] and higher levels of grehlin [an appetite stimulant] compared to extended time in bed.” (Grandner) • Circadian rhythm is affected by disruptions in hours of sleep and length of sleep. What to do? • Food intake near bedtime (late dinner or late snack—30 to 60 minutes before bed) negatively affects sleep quality. (Crispim) Eat your last meal at least 2 hours before bedtime, and keep it light. • High glycemic, carbohydrate-rich meal four hours before bed led to decrease in sleep latency (time getting to sleep). (Crispim) • However, the closer to bedtime, the more food negatively affects sleep. (Crispim) • Eat regular meals instead of snacking along. • Eat balanced meals to get a balance of nutrients. What to do? • Avoid alcohol before bedtime. • Limit caffeine to morning hours (or eliminate if necessary) • Drink adequate water during the day, but not before bedtime to avoid getting up to go to the bathroom. • Avoid spicy foods if they cause you heartburn, and thus discomfort. Harvard Women’s Health Watch, February 2014 • What you eat can affect your sleep. Spicy foods can contribute to painful heart- burn. Big meals leave you uncomfortably full, and over time can contribute to obesity—a well-known risk factor for sleep apnea. Too much caffeine could keep you wide awake, even if you finish your coffee in the morning. “It takes six hours to clear half of the caffeine from your body. If you have enough caffeine, it’s still in your body at 4 in the morning,” says Dr. Edelman. And though a glass of wine or two with dinner will make you feel relaxed or even sleepy, it won’t help you sleep. “You can fall asleep, but once you’re asleep you can’t sleep deeply,” she says. • � Solution: Eat dinner at least a couple of hours before bedtime, and keep the meal light. Avoid spicy, fatty foods, as well as alcohol and caffeine. Also, don’t drink too many fluids before bed. Having to constantly get up to go to the bathroom can disrupt your sleep, too. Nutrition Screening for Geriatric Patients • Nutrition Screening Initiative (AJPH, July, 1993) • Found that “24 percent of the Medicare population was at a high risk for nutrition problems, and • about 38 percent of that group failed to get even 75 percent of the recommended intake of three or more nutrients.” • DETERMINE checklist was developed to identify older adults at risk for nutrition problems Bibliography • Associations Between Sleep Disorders, Sleep Duration, Quality of Sleep, and Hypertension: Results From the National Health and Nutrition Examination Survey, 2005 to 2008,Pooja Bansil, MPH; Elena V. Kuklina, MD, PhD; Robert K. Merritt, MA; Paula W. Yoon, ScD, MPH, The Journal of Clinical Hypertension Vol 13 | No 10 | October 2011. • High-glycemic-index carbohydrate meals shorten sleep onset, Ahmad Afaghi, Helen O’Connor, and Chin Moi Chow, Am J Clin Nutr 2007;85:426–30. • Relationship between Food Intake and Sleep Pattern in Healthy Individuals, Cibele Aparecida Crispim, Ph.D.; Ioná Zalcman Zimberg, M.S. Bruno Gomes dos Reis, R.D.; Rafael Marques Diniz, R.D.; Sérgio Tu k, Ph.D.; Marco Túlio de Mello, Ph.D., Journal of Clinical Sleep Medicine, Vol. 7, No. 6, 2011. • Serum Nutritional Biomarkers and Their Associations with Sleep among US Adults in Recent National Surveys, May A. Beydoun, Alyssa A. Gamaldo, Jose A. Canas, Hind A. Beydoun, Mauli T. Shah, Jessica M. McNeely, Alan B. Zonderman, PLOS ONE | www.plosone.org 1..August 2014 | Volume 9 | Issue 8 | e103490. • Short Sleep Duration Is Associated with Decreased Serum Leptin, Increased Energy Intake and Decreased Diet Quality in Postmenopausal Women, Jennifer H. Stern, Andriene S. Grant, Cynthia A. Thomson, Lesley Tinker, Lauren Hale, Kathleen M. Brennan, Nancy F. Woods and Zhao Chen,Obesity | VOLUME 22 | NUMBER 5 | MAY 2014 E55. • Sleep symptoms associated with intake of specific dietary nutrients, MICHAEL A. GRANDNER, NICHOLAS JACKSON, JASON R. GERSTNER and KRISTEN L. KNUTSON, J. Sleep Res. (2014) 22-24 • Dietary Macronutrients and Sleep, Lindseth, Glenda; Murray, Ashley, West J Nurs Res August 2016 38: 938-958, first published on May 11, 2016 • An Integrative Review of Sleep for Nutrition Professionals, Devon L. Golem, Jennifer T Martin-Biggers, Mallory M. Koenings, Katherine Finn Davis, Carol Byrd Bredbenner, American Society for Nutrition. Adv. Nutr. 5: 742–759, 2014.
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