Mitosis Notes
Cell division occurs in a series of stages, or phases.
1st: INTERPHASE
• Chromosomes are copied (# doubles)
• Chromosomes appear as threadlike coils (chromatin)
at the start, but each chromosome and its copy
(sister chromosome) change to sister chromatids at
Sister chromatids
end of this phase
Centromere
2nd: PROPHASE
• Mitosis begins (cell begins to divide)
• Centrioles (or poles) appear and begin to move to
opposite ends of cell
• Spindle fibers form between the poles
3rd: METAPHASE
• Chromatids (or pairs of chromosomes) attach to the
spindle fibers
Sister
chromatids
4th: ANAPHASE
• Chromatids (or pairs of chromosomes) separate and
begin to move to opposite ends of the cell
Sister
chromatids
split
5th: TELOPHASE
• Two new nuclei form
• Chromosomes appear as chromatin (threads rather
than rods)
• Mitosis ends
6th: CYTOKINESIS
• Cell membrane moves inward to create two daughter
cells - each with its own nucleus with identical
chromosomes
Mitosis Notes
Name ______________________
__________ _________________ occurs in a series of stages, or _____________.
1st: _______________
• Chromosomes are ___________ (# doubles)
• Chromosomes appear as threadlike coils (__________________)
at the start, but each chromosome and its copy
(____________ chromosome) change to sister chromatids at
Sister chromatids
end of this phase
_________________
2nd: ______________
• ______________ begins (cell begins to divide)
• __________________ (or poles) appear and begin to move to
opposite ends of cell
• ____________ _________ form between the poles
3rd: _______________ • _________________ (or pairs of chromosomes) attach to the
spindle fibers
Sister
chromatids
4th: _______________ • Chromatids (or pairs of chromosomes) _______________ and
begin to move to ________________ ends of the cell
Sister
chromatids
split
5th: _______________ • Two new _____________ form
• Chromosomes appear as chromatin (_____________ rather
than __________)
• ________________ ends
6th: _______________ • Cell membrane moves inward to create two _________________
cells - each with its own ________________ with identical
_____________________
Mitosis Flip-Book
This activity gives students a great opportunity to use their artistic skills to learn about
mitosis. It would be most useful after students have had an introduction to mitosis.
Purpose: For students to create a visual aid to help them understand the process of
mitosis
Materials:
card cut outs (below)
markers, colored pencils, etc
stapler
textbook, or good diagram of stages of mitosis, for reference
Preparation: Give each student a copy of the mitosis cards below. it is easier if they
wait to cut them out until after they have made their drawings.
Method:
1. You can make your books as detailed as you want, as long as you realize you’ll be
drawing a lot of very similar pictures.
2. To make a good flip-book, each successive picture should vary a tiny bit from the
preceding picture. When you flip the book, the animation should be fairly
smooth. You can print extra copies of the book pages if you want to add more
intermediate frames in the flip book.
3. Imagine mitosis as a smooth process. Mitosis doesn’t happen in 4 or 5 static
frames, the way it’s depicted in textbooks. Emphasize the movement of
chromosomes.
4. Use the textbook diagrams to help draw the cell in mitosis. Remember the
changes to chromosomes, the nuclear membrane, spindle fibers, cell membrane,
etc.
Assessment:
• Flip books analyzed for the correct depiction of the five phases (i.e., chromosome
placement, presence of nuclear membrane)
• All the phases must be labeled along with the correct structures in the phases.
Lab Report:
• Write an outline that describes each step of mitosis. This outline should describe
the steps that you have done in your flip book.
Mitosis Flip Book Peer Grading Rubric
The flip book must include all of the following. Your grading scale will be out of 4 total
points for each area and 12 total points for the assignment.
4 – exceeds the standard, 3 – meets the standard
2 – meets some of the standard, 1 – meets none of the standard
Name:
1. ______ Do they have all 6 phases of mitosis in their flip book? Can you see the
centrioles, chromosomes, & spindle fibers throughout the flip book?
2. ______ Does their flip book show a smooth transition to each phases (make sure
it looks similar to the animations that we saw in class on the computer)? Did they
include all 15 pages? If they added more pages check here for extra credit. □
3. ______ Did they include a lab report that outlined the 6 phases? Does their
description match the details they have in their flip book?
Comments:
Mitosis Flip Book Peer Grading Rubric
The flip book must include all of the following. Your grading scale will be out of 4 total
points for each area and 12 total points for the assignment.
4 – exceeds the standard, 3 – meets the standard
2 – meets some of the standard, 1 – meets none of the standard
Name:
1. ______ Do they have all 6 phases of mitosis in their flip book? Can you see the
centrioles, chromosomes, & spindle fibers throughout the flip book?
2. ______ Does their flip book show a smooth transition to each phases (make sure
it looks similar to the animations that we saw in class on the computer)? Did they
include all 15 pages? If they added more pages check here for extra credit. □
3. ______ Did they include a lab report that outlined the 6 phases? Does their
description match the details they have in their flip book?
Comments
Mitosis Flip Books
Diagram Masters
You will complete each page to illustrate the changes that take place in a cell during cell division. The first oval (or ovals) in
EACH phase should show the location of the organelles at that stage. Use the extra ovals to show the movement of organelles between
stages. Once you have completed all the diagrams, carefully cut out each page, organize from first to last, and staple! Flip through your
book to view cell division!
Interphase
Mitosis Flip Book
by
_____________________
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis