OUTLINE AND COURSE INFORMATION
PHARMACEUTICS (PHM141HS) 2016-2017 WINTER
Topic
Lecturer1
Number of Hours
Winter term (39 Lectures)
1.
Introduction to Pharmaceutics & Dosage Forms M
1
2.
Biopharmaceutical Considerations
M
3
3.
Pharmaceutical Solutions
M
4
4.
Sterilization Theories and Techniques
M
3
5.
Complexation and Solubility Enhancement
M
2
6.
Preformulation
C
5
7.
Colloids and Dispersions
C
11
8.
Powders and Micromeritics
W
8
9.
Solid State Properties
W
2
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C = Tigran Chalikian; M = Robert Macgregor, W = Shirley Wu (Course coordinator).
Websites for course related handout, announcement and lecture notes:
Blackboard: Winter-2017-PHM141H1-S-LEC0101: Pharmaceutics
Pharmacy Web Site: Registered Students: Courses: PHM 141H
Class Organization and Schedule
Lectures are scheduled for Mondays at 2:00 p.m and Tuesdays at 1:00 p.m. in room PB
B150 and Fridays at 10:00 a.m. in PB B150. Tutorials will be held on Fridays at 9:00
a.m. in PB B150. Owing to the courses start a few days later and ends three days
earlier for Arts & Sci program, three lectures will be delivered at tutorial times on Fridays
at 9:00 a.m.
Tutorials: These sessions are provided for the students to ask questions about lecture
material, readings, and home work assignments, for students to write quizzes, and
for instructors and T.A.s to present supplementary material.
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Office Hours: During Office Hour sessions, a T.A. will be in the room to answer
individual students’ questions. The students should ask questions during office hour
and/or tutorial sessions instead of going to T.A.s’ labs.
Class Starts and Ends
Friday, January 6 to Tuesday, April 4.
Examinations
There will be two 2-hour examinations; they will be held respectively on March 3
and during the April examination period. The mid-term exam will cover the material up
to a week before the exam date and the final exam is cumulative covering all material
taught in the entire course. The mid-term exam will weigh 34% of total grade and the
final exam will weigh 50% of the total grade.
Problem Sets
There are two take–home problem sets and two quizzes throughout the term,
one approximately every eight lectures. The problems sets weigh 16% of total grade.
These problem sets will consist of questions and problems based upon the lectures and
readings. . We will assess your understanding of the material on the problem sets in
two ways. 1) The mark for two of the problem sets will be based on the work that you
do outside of class. Take-home problem sets handed in after 5:00 p.m. the day they
are due will not be graded, and will be assigned a score of zero. 2) The mark for the
two others will be based on your answers to a short 5- to 10-min quiz held immediate
before a lecture (TBA) one week after the problem set is distributed to you.
Relative Weight of Exams and Problem Sets
Mid-term exam
Final exam
Problem sets (2 take-home and 2 quizzes)
34 %
50 %
16 %
Missed Exam Policy
As according to Faculty policy, students presenting a valid petition for a missed
examination or quiz will be given the opportunity to write a make–up exam or quiz.
Books
The required book for PHM 141H is
Aulton's Pharmaceutics The Design and Manufacture of Medicines. 4th ed.
Churchill Livingstone.
An earlier edition is named slightly different:
Pharmaceutics: The Science of Dosage Form Design, 2nd ed. Edited by M. E. Aulton.
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Other useful books include:
Gilbaldi's Drug Delivery Systems in Pharmaceutical Care, ed. Archana Desai and Mary
Lee, American Society of Health-System Pharmacists, Inc. 2007. (This book is
also useful for Pharmacotherapy courses)
Physical Pharmacy, 4th Edition, A. Martin, 1993, Lea & Febiger, Philadelphia.
Physicochemical Principles of Pharmacy, 4th Edition, A.T. Florence & D. Attwood,
Pharmaceutical Press.
Pharmaceutical Dosage Forms and Drug Delivery Systems, 6th Edition, H. C. Ansel, N.
G. Popovich, L. V. Allen, Jr., 1995, Williams & Wilkins, Philadelphia.
Pharmaceutical Dosage Forms: Tablets vol. 1 – 3, H.A. Lieberman & L. Lachman,
Marcel Dekker.
Note that these and other books are available in the Gerstein Library. Other sources
will be recommended throughout the year, as needed. Lecture notes will also be
available on the Portal Blackboard Website.
Help and Where to Get It
There are three teaching assistants for the lecture part of PHM 141H. They are
available to answer your questions and help with assignments during the tutorial
sessions and office hours. The location and time of their office hours will be given in
class during the second week of class. The T.A.s will also grade the Problem Sets,
quizzes and Examinations.
The three teaching assistants for the course are:
Ujala Feroze (UF)
416.978.5297
[email protected]
Gloria Kim (GK)
416.978.1536
[email protected]
Kuan Chen (KC)
416.978.5744
[email protected]
The instructors are also available to answer questions or for discussion by
appointment. Please call or email first!
Tigran
416.946.3715
Chalikian
Rob Macgregor416.978.5291
1105 Pharmacy
[email protected]
1107 Pharmacy
[email protected]
Shirley
Wu
1103 Pharmacy
[email protected]
416.9785272
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