Thermo Scientific
Centrifuge Solutions for Bioprocessing
Reliable, proven solutions
for high-throughput
applications
Thermo Scientific Centrifuge
Solutions for Bioprocessing
Reliable, proven solutions for high-throughput applications
•Exceptional productivity for large volume processing – up to 12 L bottles
or 50 L/hour flow rate
•Innovative technologies to ensure processing safety, quality control and
traceability for GMP compliance, while maintaining easy-to-use operation
•Flexibility with complete range of solutions from batch processing to
continuous flow, facilitating scale-up to process development quantities
•Density Gradient Separations
•Concentration of Samples on a Cushion Eluent
Typical Applications
•Cell Harvesting
•Purification
•Virus Isolation
•Vaccine Production
Thermo Scientific Product
Max Speed/RCF
Capacity
Max Flow Rate
Sorvall® CC40/CC40S Centrifuge
40,000 rpm/118,000 xg 3.2 L max sediment
50 L/hr
TCF-32 Rotor with
Sorvall WX Ultracentrifuge
32,000 rpm/102,000 xg
940 mL max sediment
9 L/hr
TZ-28/GK Rotor with
Sorvall RC 6 Plus Superspeed Centrifuge
19,000 rpm/38,463 xg
800 mL max sediment
36 L/hr
Fiberlite® F10-4x1000 LEX Rotor with
Sorvall RC 6 Plus Superspeed Centrifuge 9,500 rpm/16,880 xg
4 L (4 x 1000 mL)
–
Fiberlite F12-6x500 LEX Rotor with
Sorvall RC 6 Plus Superspeed Centrifuge
12,000 rpm/24,500 xg
3 L (6 x 500 mL)
–
Sorvall RC 12BP Plus Centrifuge
4,700 rpm/7,340 xg
12 L(6 x 2000 mL)
–
Sorvall RC 3BP Plus Centrifuge
5,000 rpm/7,277 xg
6 L (6 x 1000 mL)
–
Sorvall RC BIOS Centrifuge
8,500 rpm/15,860 xg
6 L (6 x 1000 mL)
–
Thermo Scientific Centrifuge Solutions for Bioprocessing
Sorvall CC40/CC40S Centrifuge
Safestream, our dynamic seal technology protects against
cross contamination
• Designed expressly to purify large-volume samples, such as vaccines, with optional cores
and sample feed systems for configuration flexibility for high-throughput batch processing
• Reliable and proven solution for large-scale isolation or purification of viruses and proteins
• Minimal footprint – no need for separate air turbine compressor provides location flexibility
and quiet operation – 68 dB at 40,000 rpm – for easy in-lab placement
TCF-32 Rotor with Sorvall WX Ultracentrifuge
High g-force and large capacity reduces total run time
• Large volume separations at very high g-forces – 32,000 rpm/102,000 xg – with optional
sample feed subsystem, for simple pelleting, concentrating samples on a cushion eluent and
density gradient separations
• The unique, integrated design with an autoclavable titanium rotor body, sealing attachment
and lubricating unit, facilitates easy installation and safe, straightforward operation, including
automatic safety shut-down
• Coupling reliable, user-friendly control, compact footprint, and exceptional energy efficiency,
the Sorvall WX ultracentrifuge provides excellent operator comfort and space efficiency
TZ-28/GK Rotor with Sorvall RC 6 Plus
Superspeed Centrifuge
Reliable separations with scale-up flexibility from
superspeed applications to harvesting
• Versatile rotor designed for broad range of
applications from multi-liter cell culture
harvesting or the collection of cell-free
growth media containing excreted
products such as proteins, hormones
and vitamins
Thermo Scientific Centri-Log
Data Collection Software
A paperless process tracking and
compliance solution for large capacity
centrifuge systems
Innovative Centri-Log™ data collection software
provides effective quality control for the
documentation (logging and monitoring) of
centrifugation processes – connecting up to
32 units – enabling lifecycle management of
processed samples, equipment optimization, and
compliance with standard operating procedures.
Fiberlite F10-4x1000 LEX and Fiberlite F12-6x500 LEX Rotors
with Sorvall RC 6 Plus Superspeed Centrifuge
Lightest rotors of their kind1 for enhanced performance and safety
The next generation of high capacity Fiberlite rotors, the Fiberlite
LEX rotor series, take lightweight carbon fiber rotor design to a
whole new level for greater safety, comfort and performance
• Outstanding RCF performance for enhanced productivity – up to 16,880 xg
and 24,500 xg respectively
• Seamless integration with Thermo Scientific Nalgene bottles, including true
1L bottle for exceptional capacity for batch processing
• Corrosion- and fatigue-resistance ensures structural integrity
• Secure investment backed by a 15-year warranty
1
Based on a comparison with manufacturers' published specifications.
Thermo Scientific Fiberlite rotors with Nalgene bottles and
tubes bring together best in class quality and performance
Sorvall RC 12BP Plus Centrifuge
Large capacity batch processing with full traceability
An integrated system for high-throughput, large volume blood-banking
and bioprocessing applications
• Process up to 12 blood bag systems (up to 500 mL) or 6 x 2000 mL
Nalgene® bio-bottles for maximum productivity in a compact footprint
• Achieve reproducible results with the Thermo Scientific Accumulated
Centrifugal Effect (ACE) function, regardless of rotor loading
• Ensure effective quality control with Thermo Scientific Centri-Log data
collection software, a paperless process tracking and compliance solution
• Compact and comfortable with operator-friendly controls, ideal for
dependable, high-throughput sample processing of large volumes, at low
speeds and constant temperatures
Sorvall RC 3BP Plus Centrifuge
GMP compliance with Centri-Log data collection software
• Dependable day-to-day processing, supporting blood bags (with or without in-line
filters), tubes and bottles from 1.5 mL to 1000 mL, and as many as 18 standard
microplates
• Advanced capabilities – including ACE™, step-run and slow start/stop modes –
ensure that the centrifuge delivers precise, reproducible separations, run after run
• Safe, comfortable operation with its low deck height, quiet operation, minimal heat
output and increased refrigeration efficiency
Sorvall RC BIOS Centrifuge
Exceptional productivity with 6 liter separation capacity in just 9 minutes
• High-performance, dedicated bioprocessing system for superior yields with fast processing time
• Fiberlite F8-6x1000y carbon fiber rotor with 6-liter capacity
• 1-liter True Fit Nalgene centrifuge bottles
• Array of Thermo Scientific adapters for tube versatility
• Improves productivity and efficiency with operator friendly controls
and optimized performance for laboratory workflows
• New and enhanced security features help minimize risks of errors
and system failures and reduced variability in operating parameters
with ACE function for reliability
Thermo Scientific Centrifuge Solutions for Bioprocessing
Discover our complete range of solutions from batch processing to
continuous flow, facilitating scale-up to process development quantities.
Sorvall RC 3BP Plus Centrifuge
Sorvall RC BIOS Centrifuge
Volume: 6 L
Fiberlite LEX Rotors
Volume: 3-4 L
Compact benchtop
design with cart for
placement flexibility
Sorvall CC40 Centrifuge
Volume: 50 L/hr
TCF-32 Rotor
Volume: 9 L/h
Sorvall RC 12BP Plus Centrifuge
Volume: 12 L
TZ-28/GK Rotor
Volume: 36 L/hr
For processing large sample volumes rapidly and reliably in a single
run, our refrigerated Thermo Scientific Sorvall Stratos centrifuge is
available with continuous flow operation for up to 54 L/hr. Enabling
a more convenient and faster solution over conventional batch
separations, this centrifuge achieves 50,000 xg in 30 seconds to
quickly separate large volumes of suspension, resulting in high yields.
Contact your Thermo Scientific product representative for more information.
© 2011 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries. Specifications, terms and pricing
are subject to change. Not all products are available in all countries.
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