MCAT workshop Dr. Chace Tydell Research lab experience • UCI Bridges program http://engageinstemfc.com/opportunitiespost/ucibaccalaureateprogram/ • Long Beach State Bridges Program http://www.csulb.edu/colleges/cnsm/sas/bridges/ There are now 4 sections 1. Biological and Biochemical Foundations of Living Systems Biology, Organic Chemistry and Intro Biochemistry 2. Chemical and Physical Foundations of Biological Systems General Chemistry and Physics 3. Psychological, Social and Biological Foundations of Behavior 4. Critical Analysis and Reasoning Skills Study aids • Khan Academy MCAT test prep FREE – www.khanacademy.org/test-prep/mcat • AAMC – MCAT Official Guide $30 • aamc.org/officialmcatguide – Self assessment $104 for all 3 • aamc.org/mcatsap – Practice tests One free, others $35 • aamc.org/mcatpracticetests Some questions stand alone An ideal gas sample has a certain volume at 350 K and 1 atm. The volume of the same sample at STP will be closest to the volume at 350 K and 1 atm multiplied by: 25% 1. 2. 3. 4. 25% 25% 2 3 25% 350/273 350/298 298/350 273/350 40% hard 1 4 A teacher is interested in memory of novel words. She shows participants unrelated words printed on cards one after another. Participants see 20 words in total, wait for two minutes and then are asked to write down all of the words they can remember. 95% of the subjects remember the first three words. This is an example of: 100% 1. 2. 3. 4. recency effect proactive interference the primacy effect retroactive interference 1 The host cell is LEAST likely to contribute which of the following enzymes or enzymatic complexes to the retroviral life cycle? 25% 25% 25% 25% 1) Ribosomes 2) DNA-dependent RNA polymerase 3) RNA-dependent DNA polymerase 4) DNA-dependent DNA polymerase 45% 1 2 3 4 Which of the following would NOT change within a sarcomere during skeletal muscle contraction? 1) The length of the thick filaments 25% 2) The overlap between the thick and the thin filaments 3) The position of troponin/tropomyosin complexes on the thin filaments 4) The positions at which the globular heads of the thick filaments bind to the thin filaments 70% 1 25% 25% 2 3 25% 4 During the respiratory cycle, contraction of the diaphragm causes: 25% 1 25% 2 25% 25% 3 30% 4 1) exhalation 2) elevation of the rib 3) the intrapleural pressure to increase 4) the intra-alveolar pressure to decrease Constriction of the afferent arteriole that supplies blood directly to the glomerulus of a nephron would most immediately affect the volume of renal filtrate in which of the following tubule components of that nephron? 25% 25% 25% 25% 1) Loop of Henle 2) Proximal tubule 3) Collecting tubule 4) Bowmen’s capsule 65% 1 2 3 4 The ‘passages’ section asks you to quickly read and understand a short scientific essay (often with graphs). You will answer questions using the essay AND your own scientific knowledge. With respect to serotonin’s actions in liver regeneration as presented in this passage, serotonin can be functionally classified as: 25% 25% 25% 25% 1) An enzyme 2) A hormone 3) A clotting factor 4) A neurotransmitter 1 2 3 4 Individuals Individualsrequiring requiringaaliver livertransplant transplantoften oftenhave have reduced reducedplatelet plateletcounts. counts. Given Given the the experimental experimental results an appropriate appropriate results presented presented in in the the passage, passage, an treatment treatmentfor forthese theseindividuals individualsafter afterthey theyhave havereceived received aaportion portionof ofaadonor’s donor’sliver liverwould wouldmost mostlikely likelybe be intravenous 25% 25% 25% 25% intravenousinjections injectionsof: of: 1. 2. 3. 4. 5 HT2A and 5 HT2B antagonists An anti-platelet antibody An anti-TPH1 antibody A serotonin agonist 1 2 3 4 The serotonin precursor discussed in the passage associates directly with the enzyme TPH1. Given this, the data presented best support the conclusion that in the serotonin biosynthetic pathway, this serotonin precursor is: 25% 1 25% 25% 2 3 25% 4 1) The substrate of the TPH1-catalyzed reaction 2) The product of the TPH1-catalyzed reaction 3) A coenzyme of the TPH1-catalyzed reaction 4) An inhibitor of the TPH1-catalyzed reaction Based on the passage, platelets are LEAST likely to contain: 25% 1 25% 25% 2 3 25% 4 1) Transmembrane serotonin transporters 2) Ribosomes 3) Serotonin 4) Ki67 The liver synthesizes factors that act cooperatively with platelets to facilitate which of the following processes? 25% 25% 25% 25% 1) Cholesterol synthesis 2) Glucose metabolism 3) Blood clotting 4) Fat digestion 1 2 3 4 Study aids • Khan Academy MCAT test prep FREE – www.khanacademy.org/test-prep/mcat • AAMC – MCAT Official Guide $30 • aamc.org/officialmcatguide – Self assessment $104 for all 3 • aamc.org/mcatsap – Practice tests One free, others $35 • aamc.org/mcatpracticetests More ‘stand alone’ questions. Anxious about a nagging illness, a patient feels ignored by a doctor who is struggling to catch up with patient examinations on a very busy day. Conversely, the doctor misinterprets the discomfort and agitation of the patient as hostility. This scenario is most closely related to which paradigm? 25% 1. 2. 3. 4. 25% 25% 2 3 25% Functionalism Conflict Theory Symbolic Interactionism Social Constructionism 1 4 Among the halogens F2, Cl2, Br2 and I2, an increase in which of the following types of intermolecular forces causes an increase in boiling point going down the group? 1. Dipole-dipole forces 2. Ion-dipole forces 3. Ion-induced dipole forces 4. London dispersion forces 25% 25% 25% 2 3 25% 55% 1 4 An image of the Sun formed by a convex lens of focal length f appears at what distance from the lens? 1. 2. 3. 4. f in front of the lens f behind the lens 2f in front of the lens 2f behind the lens 25% 1 25% 25% 2 3 25% 4 Assume that a certain trait is determined by a single gene that has only two alleles and that the phenotype produced by the dominant allele is completely dominant. Given that 9% of a particular population in Hardy Weinberg equilibrium displays the recessive phenotype, what percentage of the population would both display the dominant phenotype and be capable of producing a child who displays the recessive phenotype? (Note: assume no new mutations in the gene occur.) In the MCAT, you cannot look for the ‘reasonable’ answer. Each answer to the left is the result of an incorrect formula. Assume that a certain trait is determined by a single gene that has only two alleles and that the phenotype produced by the dominant allele is completely dominant. Given that 9% of a particular population in Hardy Weinberg equilibrium displays the recessive phenotype, what percentage of the population would both display the dominant phenotype and be capable of producing a child who displays the recessive phenotype? (Note: assume no new mutations in the gene occur.) 25% 25% 25% 25% 50% 1 2 3 4 1) 21% 2) 42% 3) 49% 4) 91% They are asking ‘What is the percentage of the population that is heterozygous?’ p2+2pq+q2 1. 2. 3. 4. 5. 9% of the population is q2 so q2 = .09 If q2 = 0.09 then q = 0.3 If q = 0.3 then p = 0.7 2pq is the percentage of heterozygotes Solving the formula 2 x 0.3 x 0.7 = 2 x 0.21 = 0.42 = 42% Researchers conducted an experiment to study Weber’s aw. Going from 10- to 12-pound weights created the just noticeable difference for one participant. For this participant, how many pounds need to be added to a 20-pound weight to create the just noticeable difference? 25% 1. 2. 3. 4. 25% 25% 2 3 25% 1 pound 2 pounds 4 pounds 8 pounds 1 4
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