© Sagar Aryal
[email protected]
Department of Microbiology
St. Xavier’s College, Kathmandu, Nepal
S.N.
1.
Characteristics
Definition
2.
Purpose
3.
Enzymes Required
4.
Occurrence
5.
Raw Materials
6.
Occurrence
7.
Occurrence
8.
Bond
9.
Primers
10.
Products
Replication
DNA replication is the
process of making two
daughter strand where each
daughter strand contains half
of the original DNA double
helix.
To conserve the entire
genome for next generation.
DNA Helicase, DNA
Polymerase
Occurs in the S phase of cell
cycle.
dATP, dGTP, dTTP and
dCTP serve as raw materials.
Occurs along the strands of
DNA.
Occurs in preparation for cell
division.
Replicated DNA strand
remains hydrogen bonded to
its template DNA strand.
It require RNA primer to start
replication.
Two Daughter Strands
Transcription
Transcription is the process of
synthesis of RNA using DNA
as a template.
To make RNA copies of
individual genes.
Transcriptase (type of DNA
Helicase), RNA polymerase
Occurs in the G1 and G2
phases of cell cycle.
ATP, UTP, GTP and CTP
serve as raw materials.
Occurs along one strand of
DNA.
Occurs in preparation for
protein translation.
Transcribed RNA strand
separates from its DNA
template strand.
No primer is required to start.
mRNA, tRNA, rRNA and
non-coding RNA( like
microRNA)
© Sagar Aryal
[email protected]
Department of Microbiology
St. Xavier’s College, Kathmandu, Nepal
11.
Products
Products remain within
nucleus.
12.
Products
Products are not degraded.
13.
Copying
14.
Unwinding and
Splitting
15.
Processing
It involves copying of the
entire genome.
It involves unwinding and
splitting of the entire DNA
molecule.
It produces normal DNA
molecules that do not need
any processing.
Greater part of the product
passes from nucleus into the
cytoplasm.
Products are degraded after
their function of over.
It involves copying of certain
individual genes only.
It involves unwinding and
splitting of only those genes
which are to be transcribed.
It produces primary RNA
transcript molecule which
needs processing to acquire
final form and size.
References
1. http://www.diffen.com/difference/Replication_vs_Transcription
2. http://www.majordifferences.com/2013/10/difference-replication-vsand.html#.V_UETuh97IU
3. http://classroom.synonym.com/difference-between-transcription-dna-replication9038.html
4. https://www.reference.com/education/difference-between-replication-transcription708162c4db5645b9#
5. http://www.shmoop.com/gene-regulation-protein-synthesis/transcription-replicationdifferences.html
6. https://www.quora.com/What-are-some-differences-between-transcription-and-DNAreplication
7. https://www.quora.com/What-are-the-differences-among-replication-transcription-andtranslation
8. http://www.atdbio.com/content/14/Transcription-Translation-and-Replication
9. http://www.differencebetween.com/difference-between-dna-replication-and-vstranscription/
10. Comparing and Contrasting DNA Replication, Transcription, and Translation in a StudentCentered Environment. Amy Cash. Department of Biology. Teagle Collegium Course
Portfolio
11. DNA, RNA, replication, translation, and transcription. M. S. Shell 2009.
12. Relations Between Replication and Transcription. Daniel Castro-Roa and Nikolay Zenkin.
Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences. Newcastle
University, Newcastle upon Tyne, United Kingdom.
For Citation
Aryal S. 2016. Difference between Replication and Transcription. Accessed
from: http://www.microbiologyinfo.com/difference-replication-transcription/