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Mitosis and Cell Cycle Test
Multiple Choice
Identify the letter of the choice that best completes the statement or answers the question.
8
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1. What would be the problem with p53 being accidentally turned on in healty tissue?
a. The person would be protected from ever c. The body would get rid of the tissue and
getting cancer
replace it with healtby tissue
b. Tissue needed for normal activity would
d. The tissue would not be affected
die
2. When during the cell cycle is a cell's DNA replicated?
a. G, pbase
c. G2 phase
b. M phase
d. S phase
3. All of the following are problems that growth causes for cells EXCEPT
a. DNA overload.
c. obtaining enough food.
b. excess oxygen.
d. expelling wastes.
4. What would I see in plant cell division but 110tanimal cell division?
a. cytoplasm
c. cell plate
b. chromosomes
d. centrioles
5. How would my (Mr. Curry's) teJomeres compair to yours?
a. longer
c. shorter
b. grumpier
d. the same
o
Figure 10-1
6. The stage where DNA replicates is represented in Figure 10-1 by the Jetter
a. A.
c. C.
b. B.
d. D.
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D
7. Cells grown in a petri dish tend to divide until they form a thin layer covering the bottom of the dish. If cells
are removed from the middle of the dish, the cells bordering the open space will begin dividing until they
have filled the empty space. What does this experiment show?
a. When cells come into contact with other cells, they stop growing.
b. Cell division can be regulated by factors outside the cell.
c. The controls on cell growth and division can be turned on and off.
d. all of the above
8. Which of the following is NOT a correct statement about the events of the cell cycle?
a. Interphase is usually the longest phase.
b. The cell grows during the G2 phase.
c. DNA replicates during the S phase.
d. Cell division ends with cytokinesis.
9. Why do cells need a high surface area to volume ratio?
a. they rely on diffusion for their needs
c. they are less easy to damage when they
are small
b. cells need a high ratio in order to divide
d. they can move materials in and out faster
when they are small
10. Cancer is a disorder in which some cells have lost the ability to control their
a. spindle fibers.
c. growth rate.
b. surface area.
d. size.
I 1. What is the purpose of a telomere?
a. to protect DNA from mutations
c. to protect important DNA from being lost
when chromosomes replicate
b. to allow cancer cells to divide indefinitely d. to keep the chromosomes long enough to
do their job
12. Cancer cells form masses of cells called
a. p53.
c. growth factors.
b. cyclins.
d. tumors.
13. What happens when damage occurs to genes that regulate the cell cycle?
a. The cell can begin to divide
c. The cell's DNA will mutate
uncontrollably
b. The cell will be smaller than normal ones d. The cell can live on its own
14. Where can cancer develop in the body?
a. the lungs
c. the skin
b. the brain
d. all of the above
CIS.
When cytoplasm from a cell that is undergoing mitosis is injected into a cell that is in interphase, the second
cell begins mitosis. What does this indicate?
a. Mitosis is controlled by other cells.
c. Internal cyclins start mitosis.
b. The cell is cancerous.
d. External cyclins start mitosis.
A
B
Figure 10-2
16. Which best describes the structure in Figure 10-2?
a. Two attached chromosomes
c.
b. Two chromosomes attached at the
d.
centromere
17. During which phase(s) of mitosis are structures like
a. prophase and metaphase
c.
b. metaphase only
d.
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18. The structures labeled B in Figure 10-2 are called
a. centrioles.
c.
b. centromeres.
d.
One chromosome with two chromatids
A puffy X
the one shown in Figure 10-2 visible?
anaphase and interphase
anaphase and prophase
spindles.
sister chromatids.
19. As a cell becomes larger, its
a. surface area stays the same, but its volume increases.
b. surface area increases faster than its volume.
c. volume increases, but its surface area stays the same.
d. volume increases faster than its surface area.
20. Which is an indication that HeLa cells are cancerous?
a. they are small
c. they have 46 chromosomes
b. they are round
d. they have aneuploidys
21. During which stage of mitosis do sister chromosomes turn into daughter chromosomes?
a. during prophase
c. during cytokinesis
b. during the S phase of interphase
d. during anaphase
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22.
j3
23.
b.
D
24.
A
..»: 25.
D
26.
Which is the correct order of the phases of the cell cycle?
a. G), M, G2, S
C.
S, G). M, G2
b. G], S, G2, M
d. M, G], G2, S
Cancer affects
a. humans only.
c. most unicellular organisms.
multicellular organisms.
d. unicellular organisms.
If a cell normally has 46 chromosomes, how many chromatids would it contain during G2?
a. 23
c. 100
b. 46
d. 92
Which of the following is a correct statement about the events of the cell cycle?
a. The G] phase is usually the longest phase.
b. DNA replicates during cytokinesis.
c. Little happens during the G] and G2 phases.
d. Interphase consists of the G), S, and M phases.
Many cells never divide. These cells are termed to be in __
phase.
a. S
c. G2
b. G)
d. Go
8
27. What is the role of the spindle during mitosis?
a. It breaks down the nuclear membrane.
b. It helps separate the chromosomes.
c. It duplicates the DNA.
d. It divides the cell in half.
28. Cyclins are a family of closely related proteins that
a. produce p53.
c. regulate the cell cycle.
b. cause cancer.
d. work to heal wounds.
29. Skeletal muscle cells are very long with multiple nuclei in same cytoplasm. Which phase of the cell cycle
does not usually happen in skeletal muscle cells?
a. 01
b. metaphase
c. telophase
d. cytokinesis
_____
genes move cells forward through the cell cycle while
genes stop cells from
moving through the cell cycle.
a. proto-onco, tumor supressor
c. proto-onco, cyclins
b. tumor supresor, cyclins
d. tumor supressor, proto-onco
One difference between cell division in plant cells and in animal cells is that plant cells do not have
a. centrioles.
c. a cell plate.
b. chromatin.
d. centromeres.
32. What is the purpose of checkpoints during the cell cycle?
a. to make sure critical events have occured c. to make sure mutations are not cancerous
so the daughter cells are correctly different
fom the original cell
b. to make sure critical events have occured d. all of the above
so the daughter cells are identical to the
original cell
°33.
Which of the following represents the phases of cell division in their proper sequence?
a. interphase, prophase, metaphase, telophase
b. interphase, prophase, metaphase, anaphase, telophase
c. prophase, metaphase, anaphase, telophase, cytokinesis
d. prophase, metaphase, anaphase, telophase
34. During normal mitotic cell division, a parent cell having 46 chromosomes will produce two daughter cells,
each containing
a. 184 chromosomes
c. 46 chromosomes
b. 92 chromosomes
d. 23 chromosomes
35. Which of the following is a factor that can stop normal cells from growing?
a. a cut in the skin
b. contact with other cells
c. cyclin that has been taken from a cell in mitosis
d. growth factors
36. This dimension determines how much a cell can diffuse.
a. surface area.
c. ratio of surface area to volume.
b. volume.
d. environment.
37. The process by which a cell's nucleus divides is called ...
a. mitosis.
c. metaphase.
b. cell division.
d. interphase.
1)
B
A
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38. Which event occurs during interphase?
a. Centromeres divide.
b. Centrioles appear.
39. Which of the following could be an indication
a. They grow in a particular area of the body
b. It does not stop growing when it touches
other cells
40. This checkpoint starts the replication of DNA:
a. M
b. G2
c.
d.
that
c.
d.
c.
d.
The cell grows.
Spindle fibers begin to form.
a cell is cancerous?
It has been exposed to radiation
It undergoes mitosis quickly
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41.
Fill in the table below by placing the phases of mitosis in order. For each phase, indicate major
events focusing on the chromosomes, nucleus, centrioles and spindle. Next to each phase
make a quick sketch of what the cell should look like during that phase (consider a cell with
four chromosomes). (25 pts., 5 pts./stage)
44. I have a cell with a side length of 2~m. What would its total surface area and volume be (show
your work)? What would the surface area to volume ratio be? 4. pts.
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46.
ould it be generally better lor an organism to have cells with a high surface area to volume ratio
or a low ratio? Why? (3 pLs.)
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if·7. Why is prophase the longest stage of mitosis? (3 pts.)
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48. Why are cells like in figure A dangerous for a multiceyular
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50. What has happened to the p53 gene in the cells from figure A? How do you know? (3 pts.)
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