AKT872 - TITANIUM ISOPROPOXIDE
TITANIUM ISOPROPOXIDE
Safety Data Sheet AKT872
Date of issue: 12/30/2014
Version: 1.0
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1.
Product identifier
Product form
: Substance
Physical state
: Liquid
Substance name
: TITANIUM ISOPROPOXIDE
Product code
: AKT872
Formula
: C12H28O4Ti
Synonyms
: ISOPROPYLTITANATE; TITANIUM TETRA(2-PROPOXIDE); TETRAISOPROPYL TITANATE
Chemical family
: METAL ESTER
1.2.
Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
1.3.
: Chemical intermediate
For research and industrial use only
Details of the supplier of the safety data sheet
GELEST, INC.
11 East Steel Road
Morrisville, PA 19067
USA
T 215-547-1015 - F 215-547-2484 - (M-F): 8:00 AM - 5:30 PM EST
[email protected] - www.gelest.com
1.4.
Emergency telephone number
Emergency number
: CHEMTREC: 1-800-424-9300 (USA); +1 703-527-3887 (International)
SECTION 2: Hazards identification
2.1.
Classification of the substance or mixture
Classification (GHS-US)
Flam. Liq. 3
H226
Acute Tox. 3 (Inhalation:vapour) H331
Eye Irrit. 2A
H319
Full text of H-phrases: see section 16
2.2.
Label elements
GHS-US labeling
Hazard pictograms (GHS-US)
:
Signal word (GHS-US)
: Danger
Hazard statements (GHS-US)
: H226 - Flammable liquid and vapor
H319 - Causes serious eye irritation
H331 - Toxic if inhaled
Precautionary statements (GHS-US)
: P280 - Wear protective gloves/protective clothing/eye protection/face protection
P261 - Avoid breathing vapors
P264 - Wash hands thoroughly after handling
P210 - Keep away from heat, open flames, sparks. - No smoking
P233 - Keep container tightly closed
P240 - Ground/bond container and receiving equipment
P241 - Use explosion-proof electrical equipment
P242 - Use only non-sparking tools
P243 - Take precautionary measures against static discharge
P271 - Use only outdoors or in a well-ventilated area
P303+P361+P353 - If on skin (or hair): Take off immediately all contaminated clothing. Rinse
skin with water/shower
P304+P340 - If inhaled: Remove person to fresh air and keep comfortable for breathing
P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing
P311 - Call a doctor
P337+P313 - If eye irritation persists: Get medical advice/attention
P370+P378 - In case of fire: Use water spray or fog, foam, carbon dioxide, dry chemical to
GHS02
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GHS06
GHS07
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
extinguish
P403+P233 - Store in a well-ventilated place. Keep container tightly closed
P403+P235 - Keep in a cool place
P405 - Store locked up
P501 - Dispose of contents/container to licensed waste disposal facility.
2.3.
Other hazards
No additional information available
2.4.
Unknown acute toxicity (GHS-US)
No data available
SECTION 3: Composition/information on ingredients
3.1.
Substance
Substance type
: Multi-constituent
Name
: TITANIUM ISOPROPOXIDE
CAS No
: 546-68-9
EC no
: 208-909-6
Name
Product identifier
%
Classification (GHS-US)
Titanium isopropoxide
(CAS No) 546-68-9
> 96
Flam. Liq. 3, H226
Acute Tox. 3 (Inhalation:vapour),
H331
Eye Irrit. 2A, H319
Isopropanol
(CAS No) 67-63-0
<4
Flam. Liq. 2, H225
Acute Tox. 4 (Oral), H302
Eye Irrit. 2A, H319
STOT SE 3, H336
3.2.
Mixture
Not applicable
SECTION 4: First aid measures
4.1.
Description of first aid measures
First-aid measures general
: Remove contaminated clothing and shoes. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible). If possible show this sheet; if not
available show packaging or label.
First-aid measures after inhalation
: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately
call a poison center or doctor/physician.
First-aid measures after skin contact
: Wash with plenty of soap and water.
First-aid measures after eye contact
: Immediately flush eyes thoroughly with water for at least 15 minutes. Remove contact lenses, if
present and easy to do. Continue rinsing. Get medical advice/attention.
First-aid measures after ingestion
: Never give anything by mouth to an unconscious person. Get medical advice/attention.
4.2.
Most important symptoms and effects, both acute and delayed
Symptoms/injuries after inhalation
: Toxic if inhaled. Danger of serious damage to health by prolonged exposure through inhalation.
May cause irritation to the respiratory tract. Headache. Nausea.
Symptoms/injuries after skin contact
: May cause skin irritation.
Symptoms/injuries after eye contact
: Causes serious eye irritation.
Symptoms/injuries after ingestion
: May be harmful if swallowed.
4.3.
Indication of any immediate medical attention and special treatment needed
Note to physician: Activated charcoal slurry may be administered. Activated charcoal slurry is prepared by suspending 50 grams of activated
charcoal in 400 ml water and mixing thoroughly. Administer 5 ml/kg.
SECTION 5: Firefighting measures
5.1.
Extinguishing media
Suitable extinguishing media
5.2.
Special hazards arising from the substance or mixture
Fire hazard
5.3.
: Water spray. Water fog. Foam. Carbon dioxide. Dry chemical.
: Flammable liquid and vapor. Irritating fumes and organic acid vapors may develop when
material is exposed to elevated temperatures or open flame.
Advice for firefighters
Firefighting instructions
: Use water spray or fog for cooling exposed containers. Exercise caution when fighting any
chemical fire.
Protection during firefighting
: Do not enter fire area without proper protective equipment, including respiratory protection.
Avoid all eye and skin contact and do not breathe vapor and mist.
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
SECTION 6: Accidental release measures
6.1.
Personal precautions, protective equipment and emergency procedures
General measures
6.1.1.
: Remove ignition sources. Use special care to avoid static electric charges.
For non-emergency personnel
Emergency procedures
6.1.2.
: Evacuate unnecessary personnel.
For emergency responders
Protective equipment
6.2.
: Equip cleanup crew with proper protection.
Environmental precautions
Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters.
6.3.
Methods and material for containment and cleaning up
Methods for cleaning up
6.4.
: Clean up any spills as soon as possible, using an absorbent material to collect it. Sweep or
shovel spills into appropriate container for disposal. Use only non-sparking tools.
Reference to other sections
See Heading 8. Exposure controls and personal protection.
SECTION 7: Handling and storage
7.1.
Precautions for safe handling
Additional hazards when processed
: Handle empty containers with care because residual vapors are flammable.
Precautions for safe handling
: Avoid all eye and skin contact and do not breathe vapor and mist. Provide good ventilation in
process area to prevent accumulation of vapors. Take precautionary measures against static
discharge. Containers and transfer lines require grounding during use. Use only non-sparking
tools.
Hygiene measures
: Wash hands and other exposed areas with mild soap and water before eating, drinking or
smoking and when leaving work. Wash contaminated clothing before reuse.
7.2.
Conditions for safe storage, including any incompatibilities
Technical measures
: Ground/bond container and receiving equipment. Proper grounding procedures to avoid static
electricity should be followed. Use explosion-proof electrical equipment.
Storage conditions
: Keep container tightly closed.
Incompatible materials
: Moist air. Oxidizing agent. Water.
Storage area
: Store in a well-ventilated place. Store away from heat.
7.3.
Specific end use(s)
No additional information available
SECTION 8: Exposure controls/personal protection
8.1.
Control parameters
Isopropanol (67-63-0)
USA ACGIH
ACGIH TWA (ppm)
200 ppm
USA ACGIH
ACGIH STEL (ppm)
400 ppm
USA NIOSH
NIOSH REL (TWA) (mg/m³)
980 mg/m³
USA NIOSH
NIOSH REL (TWA) (ppm)
400 ppm
USA NIOSH
NIOSH REL (STEL) (mg/m³)
1225 mg/m³
USA NIOSH
NIOSH REL (STEL) (ppm)
500 ppm
USA OSHA
OSHA PEL (TWA) (mg/m³)
980 mg/m³
USA OSHA
OSHA PEL (TWA) (ppm)
400 ppm
USA IDLH
US IDLH (ppm)
2000 ppm (10% LEL)
8.2.
Exposure controls
Appropriate engineering controls
: Provide local exhaust or general room ventilation.
Personal protective equipment
: Avoid all unnecessary exposure. Emergency eye wash fountains and safety showers should be
available in the immediate vicinity of any potential exposure.
Hand protection
: Neoprene or nitrile rubber gloves.
Eye protection
: Chemical goggles. Contact lenses should not be worn.
Skin and body protection
: Wear suitable protective clothing.
Respiratory protection
: NIOSH-certified organic vapor (black cartridge) respirator.
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
SECTION 9: Physical and chemical properties
9.1.
Information on basic physical and chemical properties
Physical state
: Liquid
Appearance
: Clear liquid. Freezes in winter.
Molecular mass
: 284.25 g/mol
Color
: Pale yellow.
Odor
: No data available
Odor threshold
: No data available
Refractive index
: 1.4654
pH
: No data available
Relative evaporation rate (butyl acetate=1)
: No data available
Melting point
: No data available
Freezing point
: 15 - 19 °C
Boiling point
: 58 °C @ 1 mm Hg
Flash point
: 25 °C
Auto-ignition temperature
: 580
Decomposition temperature
: No data available
Flammability (solid, gas)
: Flammable liquid and vapor
Vapor pressure
: 19 mm Hg @ 100˚C
Vapor pressure at 50 °C
: 0.9 mm Hg
Relative vapor density at 20 °C
: >1
Relative density
: 0.937
Solubility
: Reacts with water.
Log Pow
: No data available
Log Kow
: No data available
Viscosity, kinematic
: 2 cSt
Viscosity, dynamic
: No data available
Explosive properties
: No data available
Oxidizing properties
: No data available
Explosive limits
: No data available
9.2.
Other information
No additional information available
SECTION 10: Stability and reactivity
10.1.
Reactivity
No additional information available
10.2.
Chemical stability
Stable.
10.3.
Possibility of hazardous reactions
Material decomposes slowly in contact with moist air and rapidly in contact with water liberating isopropanol.
10.4.
Conditions to avoid
Heat. Open flame. Sparks.
10.5.
Incompatible materials
Oxidizing agent.
10.6.
Hazardous decomposition products
Isopropanol. Organic acid vapors. Titanium oxide.
SECTION 11: Toxicological information
11.1.
Information on toxicological effects
Acute toxicity
Titanium isopropoxide (546-68-9)
LD50 oral rat
LD50 dermal rabbit
LC50 inhalation rat
ATE US (oral)
ATE US (vapors)
12/30/2014
: Inhalation:vapour: Toxic if inhaled.
7460 mg/kg
> 16 ml/kg
7.78 mg/l/4h
7460.000 mg/kg body weight
7.780 mg/l/4h
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
Isopropanol (67-63-0)
LD50 oral rat
LD50 dermal rabbit
LC50 inhalation rat (mg/l)
ATE US (oral)
ATE US (dermal)
Skin corrosion/irritation
1870 mg/kg
4059 mg/kg
72600 mg/m³ (Exposure time: 4 h)
1870.000 mg/kg body weight
4059.000 mg/kg body weight
: Not classified
Serious eye damage/irritation
: Causes serious eye irritation.
Respiratory or skin sensitization
: Not classified
Germ cell mutagenicity
: Not classified
Carcinogenicity
: Not classified
Isopropanol (67-63-0)
IARC group
3 - Not classifiable
Reproductive toxicity
: Not classified
Specific target organ toxicity (single exposure)
: Not classified
Specific target organ toxicity (repeated
exposure)
: Not classified
Aspiration hazard
: Not classified
Symptoms/injuries after inhalation
: Toxic if inhaled. Danger of serious damage to health by prolonged exposure through inhalation.
May cause irritation to the respiratory tract. Headache. Nausea.
Symptoms/injuries after skin contact
: May cause skin irritation.
Symptoms/injuries after eye contact
: Causes serious eye irritation.
Symptoms/injuries after ingestion
: May be harmful if swallowed.
Reason for classification
: Expert judgment
SECTION 12: Ecological information
12.1.
Toxicity
Isopropanol (67-63-0)
LC50 fish 1
EC50 Daphnia 1
LC50 fish 2
12.2.
9640 mg/l (Exposure time: 96 h - Species: Pimephales promelas [flow-through])
13299 mg/l (Exposure time: 48 h - Species: Daphnia magna)
11130 mg/l (Exposure time: 96 h - Species: Pimephales promelas [static])
Persistence and degradability
No additional information available
12.3.
Bioaccumulative potential
Isopropanol (67-63-0)
Log Pow
12.4.
0.05 (at 25 °C)
Mobility in soil
No additional information available
12.5.
Other adverse effects
Effect on ozone layer
: No additional information available
Effect on the global warming
: No known ecological damage caused by this product.
SECTION 13: Disposal considerations
13.1.
Waste treatment methods
Waste disposal recommendations
: Incinerate. Dispose in a safe manner in accordance with local/national regulations. Dispose of
contents/container to licensed waste disposal facility.
Ecology - waste materials
: Avoid release to the environment.
SECTION 14: Transport information
14.1.
UN number
UN-No.(DOT)
DOT NA no.
14.2.
: 2413
UN2413
UN proper shipping name
Proper Shipping Name (DOT)
: Tetrapropylorthotitanate
Department of Transportation (DOT) Hazard
Classes
: 3 - Class 3 - Flammable and combustible liquid 49 CFR 173.120
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
Hazard labels (DOT)
: 3 - Flammable liquid
Packing group (DOT)
: III - Minor Danger
DOT Packaging Exceptions (49 CFR 173.xxx)
: 150
DOT Packaging Non Bulk (49 CFR 173.xxx)
: 203
DOT Packaging Bulk (49 CFR 173.xxx)
: 242
14.3.
Additional information
Other information
: No supplementary information available.
Transport by sea
DOT Vessel Stowage Location
: A - The material may be stowed ‘‘on deck’’ or ‘‘under deck’’ on a cargo vessel and on a
passenger vessel.
Air transport
DOT Quantity Limitations Passenger aircraft/rail
(49 CFR 173.27)
: 60 L
DOT Quantity Limitations Cargo aircraft only (49 : 220 L
CFR 175.75)
SECTION 15: Regulatory information
15.1. US Federal regulations
Titanium isopropoxide (546-68-9)
Listed on the United States TSCA (Toxic Substances Control Act) inventory
Isopropanol (67-63-0)
Listed on the United States TSCA (Toxic Substances Control Act) inventory
Listed on United States SARA Section 313
EPA TSCA Regulatory Flag
T - T - indicates a substance that is the subject of a Section 4 test rule under TSCA.
SARA Section 313 - Emission Reporting
1.0 % (only if manufactured by the strong acid process, no supplier notification)
15.2. International regulations
Titanium isopropoxide (546-68-9)
Listed on the AICS (Australian Inventory of Chemical Substances)
Listed on the Canadian DSL (Domestic Sustances List)
Listed on IECSC (Inventory of Existing Chemical Substances Produced or Imported in China)
Listed on the EEC inventory EINECS (European Inventory of Existing Commercial Chemical Substances)
Listed on the Japanese ENCS (Existing & New Chemical Substances) inventory
Listed on the Korean ECL (Existing Chemicals List)
Listed on NZIoC (New Zealand Inventory of Chemicals)
Listed on PICCS (Philippines Inventory of Chemicals and Chemical Substances)
Isopropanol (67-63-0)
Listed on the AICS (Australian Inventory of Chemical Substances)
Listed on the Canadian DSL (Domestic Sustances List)
Listed on IECSC (Inventory of Existing Chemical Substances Produced or Imported in China)
Listed on the EEC inventory EINECS (European Inventory of Existing Commercial Chemical Substances)
Listed on the Japanese ENCS (Existing & New Chemical Substances) inventory
Listed on the Japanese ISHL (Industrial Safety and Health Law)
Listed on the Korean ECL (Existing Chemicals List)
Listed on NZIoC (New Zealand Inventory of Chemicals)
Listed on PICCS (Philippines Inventory of Chemicals and Chemical Substances)
Listed on the Canadian IDL (Ingredient Disclosure List)
15.3. US State regulations
TITANIUM ISOPROPOXIDE(546-68-9)
U.S. - California - Proposition 65 - Carcinogens List
No
U.S. - California - Proposition 65 - Developmental
Toxicity
No
U.S. - California - Proposition 65 - Reproductive
Toxicity - Female
No
U.S. - California - Proposition 65 - Reproductive
Toxicity - Male
No
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TITANIUM ISOPROPOXIDE
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Titanium isopropoxide (546-68-9)
U.S. - California U.S. - California Proposition 65 Proposition 65 Carcinogens List
Developmental Toxicity
U.S. - California Proposition 65 Reproductive Toxicity Female
U.S. - California Proposition 65 Reproductive Toxicity Male
No
No
No
No
Isopropanol (67-63-0)
U.S. - California Proposition 65 Carcinogens List
U.S. - California Proposition 65 Developmental Toxicity
U.S. - California Proposition 65 Reproductive Toxicity Female
U.S. - California Proposition 65 Reproductive Toxicity Male
No
No
No
No
No significance risk level
(NSRL)
No significance risk level
(NSRL)
Titanium isopropoxide (546-68-9)
U.S. - Texas - Effects Screening Levels - Long Term
U.S. - Texas - Effects Screening Levels - Short Term
Isopropanol (67-63-0)
U.S. - California - SCAQMD - Toxic Air Contaminants - Non-Cancer Acute
U.S. - California - SCAQMD - Toxic Air Contaminants - Non-Cancer Chronic
U.S. - California - Toxic Air Contaminant List (AB 1807, AB 2728)
U.S. - Connecticut - Hazardous Air Pollutants - HLVs (30 min)
U.S. - Connecticut - Hazardous Air Pollutants - HLVs (8 hr)
U.S. - Connecticut - Volatile Substances
U.S. - Idaho - Non-Carcinogenic Toxic Air Pollutants - Acceptable Ambient Concentrations
U.S. - Idaho - Non-Carcinogenic Toxic Air Pollutants - Emission Levels (ELs)
U.S. - Idaho - Occupational Exposure Limits - TWAs
U.S. - Massachusetts - Right To Know List
U.S. - Massachusetts - Toxics Use Reduction Act
U.S. - Michigan - Occupational Exposure Limits - STELs
U.S. - Michigan - Occupational Exposure Limits - TWAs
U.S. - Minnesota - Hazardous Substance List
U.S. - Minnesota - Permissible Exposure Limits - STELs
U.S. - Minnesota - Permissible Exposure Limits - TWAs
U.S. - New Hampshire - Regulated Toxic Air Pollutants - Ambient Air Levels (AALs) - 24-Hour
U.S. - New Hampshire - Regulated Toxic Air Pollutants - Ambient Air Levels (AALs) - Annual
U.S. - New Jersey - Discharge Prevention - List of Hazardous Substances
U.S. - New Jersey - Environmental Hazardous Substances List
U.S. - New Jersey - Right to Know Hazardous Substance List
U.S. - New Jersey - Special Health Hazards Substances List
U.S. - New York - Occupational Exposure Limits - TWAs
U.S. - North Dakota - Air Pollutants - Guideline Concentrations - 1-Hour
U.S. - North Dakota - Air Pollutants - Guideline Concentrations - 8-Hour
U.S. - Oregon - Permissible Exposure Limits - TWAs
U.S. - Pennsylvania - RTK (Right to Know) - Environmental Hazard List
U.S. - Pennsylvania - RTK (Right to Know) List
U.S. - Rhode Island - Air Toxics - Acceptable Ambient Levels - 1-Hour
U.S. - Tennessee - Occupational Exposure Limits - STELs
U.S. - Tennessee - Occupational Exposure Limits - TWAs
U.S. - Texas - City of Austin - Aerosol Paint and Glue Restrictions
U.S. - Texas - Effects Screening Levels - Long Term
U.S. - Texas - Effects Screening Levels - Short Term
U.S. - Vermont - Permissible Exposure Limits - STELs
U.S. - Vermont - Permissible Exposure Limits - TWAs
U.S. - Washington - Permissible Exposure Limits - STELs
U.S. - Washington - Permissible Exposure Limits - TWAs
SECTION 16: Other information
Abbreviations and acronyms
: Abbreviations: ND: Not Determined, No Data; NA: Not Applicable; LD: Lethal Dose; LC: Lethal
Concentration; ATE: Acute Toxicity Estimates; H: hour; °: °C unless otherwise stated; mm:
millimeters Hg, torr; PEL: permissible exposure level; TWA: time weighted average; TLV:
threshold limit value; TG: Test Guideline; NIOSH: National Institute for Occupational Safety and
Health; IARC: International Agency for Research on Cancer; NTP: National Toxicology
Program; HMIS: Hazardous Material Information System; CAS No.: Chemcial Abstract Service
Registration Number; EC No.: European Commission Registration Number; EC Index No.:
European Commission Index Number; OECD: The Organisation for Economic Co-operation
and Development.
Full text of H-phrases::
-----Acute Tox. 3 (Inhalation:vapour)
-----Acute Tox. 4 (Oral)
-----Eye Irrit. 2A
12/30/2014
Acute toxicity (inhalation:vapor) Category 3
Acute toxicity (oral) Category 4
Serious eye damage/eye irritation Category 2A
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TITANIUM ISOPROPOXIDE
Safety Data Sheet
----------------------------------------------
Flam. Liq. 2
Flam. Liq. 3
STOT SE 3
H225
H226
H302
H319
H331
H336
Flammable liquids Category 2
Flammable liquids Category 3
Specific target organ toxicity (single exposure) Category 3
Highly flammable liquid and vapor
Flammable liquid and vapor
Harmful if swallowed
Causes serious eye irritation
Toxic if inhaled
May cause drowsiness or dizziness
HMIS III Rating
Health
: 2 Moderate Hazard - Temporary or minor injury may occur
Flammability
: 3 Serious Hazard
Physical
: 1 Slight Hazard
Prepared by safety and environmental affairs.
Date of issue: 12/30/2014
Version: 1.0
SDS US (GHS HazCom 2012) - Custom
According to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations
The information contained in this document has been gathered from reference materials and/or Gelest, Inc. test data and is to the best knowledge and belief of Gelest, Inc. accurate and reliable.
Such information is offered solely for your consideration, investigation and verification. It is not suggested or guaranteed that the hazard precautions or procedures described are the only ones which
exist. Gelest, Inc. makes no warranties, express or implied, with respect to the use of such information and assumes no responsibility therefore. Information on this safety data sheet is not intended
to constitute a basis for product specifications.
© 2014 Gelest Inc. Morrisville, PA 19067
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