SOLUTIONS 10 Digital blister lid foil printing: Reduced setup times, lower costs For small batches: DoD UV inkjet printing is more efficient than flexography, says Helmut Schneider, Product Group Manager Pharma & Packaging Solutions. Production runs for blister lid foil printing medicine are then being produced. inevitably increasing in number as are becoming ever shorter. The efficiency Furthermore, many pharmaceutical production runs become shorter. Flexo of flexographic printing, with its relatively companies are affected by the expiry of printing’s key strength – the lower costs long setup times, is suffering as a result. patents on their blockbuster drugs. As of printing ink – is practically cancelled Fully digital drop on demand UV inkjet they search for new best-sellers, more out. Instead, downtimes become longer printing technology can keep the costs in clinical trials are required which also and high operating costs result, without check even with small and medium-size involve relatively small batch sizes. In the user being able to reap the original batches. addition, each country has its own benefit in return. Until now, pharmaceutical regulations concerning the printing of Simply by loading a PDF producers, packaging service providers blister packs e.g. concerning warning and foil manufacturers have primarily statements or symbols. All these reasons used UV flexography for printing blister are factors in a trend that will see batch DoD UV inkjet digital printing offers an lid foil. Its advantages come into play sizes become even smaller, often falling economically highly attractive alternative. with long production runs and large batch below 100,000 blisters per production DoD stands for drop on demand. Piezo- sizes in particular. As long as changeovers run. electric components fire tiny droplets of caused by different production jobs are At the same time, the production ink through microscopic apertures onto infrequent, the costs of consumables procedures and packaging processes in the substrate being printed. Dried by UV and printing ink in particular are what the pharmaceutical industry are already light in a fraction of a second, the printing determine a plant’s efficiency. But as the highly standardized and very efficiently on many different materials is extremely number of changeovers rises, the high organized. Increasing the pure speed durable and offers good resistance to downtimes and setup times that occur of the line is often no longer feasible abrasion and solvents. Building on this with flexo printing assume much greater economically and would at any rate technology, Atlantic Zeiser has developed proportions, so that the costs for printing produce only marginal improvements in the DIGILINE Blister, a fully digital ink then become virtually irrelevant. And efficiency. A production plant’s efficiency system for printing blister lid foil up to a clear trend is now emerging towards therefore primarily depends on the 330 mm wide that can easily be inte- ever smaller production runs in future. number and duration of its idle times – grated inline into blister packaging There are various reasons for this. On the for changeovers, for instance, that are machines. Its production speed of up to one hand, medicine and drug budgets in many countries are coming under substantial pressure, so that pharmaceutical companies are having to contend with reduced margins. In such a situation the aim is to minimize the amount of capital tied up in stock, in this instance either in the form of pre-printed lid foil and/or products ready for shipment that are not immediately required. On the other, it is evident that a growing number of preparations are being tailored to suit specific patient groups, for instance to match patients’ typical clinical picture, or according to sex, age, lifestyle etc. Significantly smaller quantities of each 11 30 meters per minute matches the There are also maintenance considera- maximum performance of a conventional tions that should not be overlooked: the blister packaging machine. As an option, DIGILINE Blister’s contactless inkjets are the system is also available in a near-line subject to little or no wear. An automatic variant and as a roll-to-roll offline version cleaning function ensures the print heads for pre-production and just-in-time are ready for operation. The actual cleaning provision to several packaging lines. process only takes around half a minute The key benefit of DoD UV inkjet and is automated, that is to say, the technology is that, unlike flexography, it cleaning results are always reproducible – does not involve any time-consuming and the life of the print heads is practically mechanical effort, such as required to unlimited. The UV special ink that is used change, clean, store and retrieve the print With setups that take just two minutes rather than an hour, the DIGILINE Blister can therefore print small and medium-size production runs with up to 100,000 blisters very cost-effectively. mats, for instance. To start a new print for printing with the DIGILINE Blister is job on the DIGILINE Blister, a new PDF designed for high sealing temperatures simply has to be loaded. Whereas with a and is suitable for both rotary and platen conventional flexo printing system a good sealing. The quantity of ink can be hour (and therefore several thousand adjusted to suit the special characteristics euros) must be allowed on average for a of a particular foil. Alternative foil materials product changeover including organiza- e.g. Tyvek can also be printed with the across several locations – for example for tional input, the same task takes no system. So users need not accept the administration and allocation of jobs, longer than two minutes with the compromises as regards print quality. recording of audit trail information or the DIGILINE Blister. The system already has The DIGILINE Blister is capable of setup and management of user rights. an original PDF processing algorithm faithfully reproducing even complex installed for job setups, so that additional Asian scripts and very small fonts down to fewer opportunities for flexo printing to software or hardware are not necessary. 4 point thanks to a native PDF resolution exploit its strengths because batches are If demand for a particular printing variant of 600 x 600 dpi. Because the printing getting noticeably smaller. Short setup arises at short notice, it can be met almost system is digital, additional information times and the low operating costs of the instantly and with limited stocks – a major such as expiry date and lot number or entire system then give fully digital advantage, especially for service providers. even variable datamatrix codes can be printing technology the edge, without the easily applied. Although hybrid flexogra- user having to make concessions. phic machines have in the meantime Atlantic Zeiser has proved how this become available that can do this too, works: for printing small to medium-size the other drawbacks of flexography batches of up to around 100,000 blisters, remain. the DIGILINE Blister is currently one of Low operating costs, minimum wear As well as the simple job setup, the the most cost-efficient systems. DIGILINE Blister is also characterized by relatively low operating costs: on the one hand, the cost of sourcing flexo print To sum up, there are fewer and Smooth exchange of information mats and the associated logistical input for their installation, removal, cleaning Not only can the DIGILINE Blister and storage is eliminated. On the other, exchange production-related data with the UV-A lamps for the DoD inkjet the entire packaging line, but it can printing are based on LED technology also be completely controlled via the and last around ten times longer than the user interface of the blister packaging UV-C curing lamps used in flexography, machine. A further advantage is the that is to say for up to 20,000 operating option of connection to Atlantic Zeiser’s hours. Furthermore, the UV-A LED MEDTRACKER serialization software via technology uses considerably less the VDMA-XML interface, thus permitting energy and notably does not need an optimum integration in the workflow. extraction system for the large volume of MEDTRACKER can function as the heat that arises with conventional UV-C central platform for the production dryers. management of several plants – including
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