Can India Benefit from the Agricultural Biotechnology? C. S. Prakash* mong India's greatest achievements since its A independence is it's increased food production. While Indians averted an imminent famine in the 1960's through food imports, they are now in an enviable situation as a food exporter. India has increased food grain production more than three-fold in the last three decades primarily by the application of genetics in improving crop varieties, along with expanded irrigation, better management practices and institutional factors such as farm policies, credit availability and market forces. But India with its current population of one billion still faces daunting challenges of hunger, poverty and malnutrition that will only get worse as its population further increases. The World Bank predicts that by 2020 India will be the fourth-largest economy in the world behind China, US and Japan. But India cannot propel itself into a global economic power and also ensure equitable prosperity of its people without first transforming its agriculture into a more productive enterprise. Almost twothirds of Indians depend on the land for their livelihood, through food production, distribution, marketing or processing. of harvested fruits and vegetables are spoilt during transportation and storage. Biotechnology, if deployed in a strategic and responsible manner, will help address some of these problems. Biotechnology can be a boon to Indian agriculture in many ways. Crop damage can be minimised through disease and pest resistant varieties while reducing the use of chemicals. The Indian pepper crop is now ravaged by the dieback disease, while the banana is being ambushed by the bunchy top disease, sorghum eroded by downy mildew, and the coconut is crippled by the Tanjore wilt problem. Conventional plant breeding has little ammunition to deal with these problems in an expedient and effective manner. India also has serious problems of blast in rice, rust in wheat, leaf rust in coffee, viruses in tomato and chillies and leaf spot in groundnut across the country. These problems can be significantly minimised in an Transforming India's agriculture is critical not only to deal with the issue of hunger and poverty but also to strengthen the sector that is so fundamental to India's existence. The ‘green revolution’ is showing signs of fatigue and farm productivity increases are now flattening. There are serious constraints to productivity in Indian agriculture because of small holdings, the subsistence nature of farming, vagaries of the weather, limited water, poor land conditions and stress factors such as drought, heat and saline soil conditions. Much of the crop yield is lost due to disease, pests, and weeds while a considerable proportion *Dr. C. S. Prakash is Professor and Director of the Centre for Plant Biotechnology Research at Tuskegee University, Alabama, USA. He is the founder of the ‘Society for Biotechnology’ in Bangalore, India, and is among the founding members of an Internet-based network called PBASIO, the ‘Plant Biotechnologists and Agricultural Scientists of Indian Origin’ which has more than 800 members and promotes discussion on agbiotech related issues concerning India. He can be reached at [email protected]. 76 BTV4•4/part1 APBN • Vol. 4 • No. 4 • 2000 76 2/9/00, 9:12 AM ASIA-PACIFIC BI TECH NEWS ecologically-friendly manner with the development of genetically reprogrammed seeds designed to resist these disease attacks, while minimising or even eliminating costly and hazardous pesticide sprays. Genetic modification can also address the problems of shoot borers in eggplant and okra, caterpillars in pappadi (Dolichos) beans, and of course, the boll worm in cotton which resulted in the tragic suicides of hundreds of cotton farmers. India is the third largest producer of cotton in the world (after China and the USA) accounting for a large share of global production. Although cotton occupies only 5% of the country's land, nearly 50% of all pesticide used in India is bought by cotton farmers alone at a staggering cost of US$400 million annually and with incalculable impact on the environment and human health. Development of cotton varieties with resistance to pests thus can enhance the welfare of Indian farmers, while helping both the Indian economy and its environment. New genome technologies along with bioinformatics will further propel Indian agriculture into a new era where complex traits such as photosynthetic efficiency and crop yield can be enhanced. Genomic tools with esoteric names such as ‘DNA Chips’, ‘Gene Shuffling’ and ‘Directed Evolution’ are already making an impact on biomedical research enabling the discovery of new drugs and rapid disease diagnostics, and will surely impact agricultural research. With no more arable land available for agricultural expansion in India, enhancing stress tolerance in crop plants will permit productive farming on currently unproductive lands. Abiotic factors such as drought, heat, cold, soil salinity and acidity cripple Indian crops seriously constraining their growth and yield. One could extend the growing season of crops and minimise losses due to environmental factors. The shelf life of fruits and vegetables can be prolonged to reduce losses due to food spoilage, expand the market vista and improve food quality. Prolonged ‘vase life’ of cut-flowers will help broaden the market for horticulturists, while reducing losses and minimising their dependency on expensive cold storage. Human and livestock health can be improved through crops with enhanced nutritional quality traits such as iron-rich rice and vitamin A-rich rapeseed oil, and through the production of edible vaccines and other pharmaceutical proteins. Crops with industrial applications such as those producing enzymes, ‘designer’ starch and oils, biodegradable plastics and industrial chemicals can also be developed to reinvigorate the Indian economy and create jobs. Crop plants that can clean up soil, water and air through ‘phytoremediation’ can be developed and planted in critical areas. Trees that grow faster with fewer disease and pest problems can be developed with positive impact both on the rural economy and the environment. There has been much human misery caused by hazardous substances in many Indian food crops — such as the presence of neurotoxin in kesar dal, cyanide in cassava or tapioca, aflatoxins in groundnut and antimetabolites in chickpea, horsegram and sweet potato. Biotechnology has the capability to ‘silence’ these undesirable traits and thus improve the quality of these ‘humble’ food crops so critical to the nutrition of disadvantaged and resource-poor consumers. Biotechnology has made modest advances in agricultural research in India. Several institutions such as the Indian Agricultural Research Institute, Bose Institute, National Chemical Laboratory, and Indian Institute of Science along with many other traditional and agricultural universities have established modern biotechnology research programs, primarily with funding from the Government of India's Department of Biotechnology. However, the impact of these research programs, either in advancing fundamental APBN • Vol. 4 • No. 4 • 2000 BTV4•4/part1 77 2/9/00, 9:13 AM 77 knowledge or in the development of improved products for the marketplace has been minimal albeit with few exceptions. It is critical that public sector research in biotechnology be strengthened in India and to ensure that such technology transferred to the farm in an expedient manner. Several Indian companies have also recently established R&D centres to develop genetically improved crops mostly in collaboration with foreign companies, including Mahyco Seeds, SPIC, ITC, Pioneer India, Indo-American Hybrid Seeds and ProAgro Seed. Monsanto, the American company known for its technological strengths in this field, has set up a multi-million dollar research facility on the campus of the Indian Institute of Science to develop genetically improved crops for India, and has also established a partnership with Mahyco seeds to develop improved cotton varieties for the Indian farmer. The strategic integration of biotechnology tools into Indian agricultural systems can revolutionise Indian farming and usher in a new era in the countryside. Compared to the “green revolution”, the “gene revolution” is relatively scale neutral, benefiting big and small farmers alike. It is also environment friendly. Thus, it can be of great help to the smallest farmer with limited resources, in increasing farm productivity through the availability of improved but powerful seed. It can also reduce his dependency on chemical inputs such as pesticides and fertiliser. India unequivocally needs the help of such technologies to march into the next century with a vision for economic upliftment and prosperity for its two-thirds of populace dependent on farming. While most scientists and policy-makers recognise that biotechnology is not a panacea for all food production problems in India, it is the single most powerful tool India has right now to address this problem. There are risks inherent in any technological intervention. Human beings down the centuries have learnt to weigh the perceived and real risks against the benefits of emerging technologies, and have responsibly integrated these to foster progress. What we need is a sensible and responsible approach to integrating biotechnology in Indian agricultural research while ensuring that any risk posed by this technology is kept to a minimum through rigorous scientific approach. crops by developing a strong, reliable and trustworthy regulatory mechanism. The existing biosafety framework now requires that all genetically modified organisms must undergo a rigorous review and safety assessment prior to their import, field testing or release. The government should also enhance its legal system by instituting penalties for those who do not follow the regulations, strengthen and enforce its anti-trust laws to prevent monopolies and impose product-liability laws to force corporate responsibility. Scientists and companies involved in genetically improved crop development, on their part, have an obligation to be more open about their affairs and make concerted efforts to communicate with farmers and the public about the nature of their products and any inherent risks they pose. A revitalised Indian agriculture can be the engine of growth for the 21st century, and biotechnology can provide the needed fuel. When deployed in a sensible and responsible manner, modern biotechnological tools can advance India's agriculture to address ‘head-on’ the challenge of feeding its increasing population in a sustainable manner despite its limited economic, land and water resources. India cannot afford to lag behind in critically examining these new technologies and making them available to its farmers under suitable safeguards. “ The strategic integration of biotechnology tools into Indian agricultural systems can revolutionise Indian farming and usher in a new era in the countryside. Compared to the “green revolution”, the “gene revolution” is relatively scale neutral, benefiting big and small farmers alike. It is also environment friendly. ” The Government of India's Department of Biotechnology and other scientific agencies have done admirable work to deal with safety issues of genetically improved 78 BTV4•4/part1 APBN • Vol. 4 • No. 4 • 2000 78 2/9/00, 9:13 AM
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