Inguinal and Scrotal Pathology Dr Andre Theron Paediatric Surgery Charlotte Maxeke Johannesburg Academic Hospital UP TO SPAED 2016 Inguinal and Scrotal Pathology • Hernia and Hydrocele • Undescended – – – – – Retractile testis Canalicular testis Abdominal testis Vanished testis Ectopic Testis – – – – – – Torsion of Testis Torsion of appendix testis Epididymo-orchitis Strangulated hernia Idiopathic scrotal oedema Haematoma • Acute scrotum: • Testicular mass: – Teratoma – Orchioblastoma, germ cell tumour; Interstitial cell tumours (Leydig, Sertoli) • Inguinal Lymphadenitis Inguinal and Scrotal Pathology Anatomy and core embryology • Congenital inguinal hernia and undescended testis are related to testicular descent • The testes develop in the abdomen and descend into the scrotum under the influence of hormones, pulling down the processus vaginalis • The testes reach the scrotum by the 3rd trimester • In +/-90% of children, the processus vaginalis seals and becomes a thin band of tissue • If all or any portion of the processus remains open it may result in a congenital inguinal hernia, hydrocoele or a communicating hydrocoele • Patency of the processus vaginalis decreases with increasing gestational age • In girls, hernias are less common than in boys (1:8) Inguinal Hernia- Incidence • Indirect hernia - most commonly • • • • • • • – with a patent processus vaginalis Direct hernias rare 3% - 5% of term infants 9% - 11% of pre term babies 35% if < 28 weeks 60% right, 25% left, 15% Bilat. M>F, bilateral. F>M Increased incidence in patients on peritoneal dialysis, VP shunts • At least 5% bilateral Inguinal Hernia- Physical Examination • A bulge in the groin or the scrotal sac, worse on straining or crying, cough impulse • Rely on history • “silk string” sign • Determine difference between a hernia, hydrocele and communicating hydrocele • A non-communicating hydrocele usually presents as a soft, non-tender, fluid-filled sac in the scrotum which does not change in size over the course of the day • Check for testicular descent in boys Inguinal Hernia - Incarcerated Hernia • Incarceration or irreducibility is most common complication – 30 % in 1st year of a term baby – 12% below 12yrs, • Most commonly bowel, ovary in Female • Presents as sudden onset of a irreducible swelling in scrotum or groin, bowel obstruction • Failure to reduce can lead to strangulation of contents and ischemia of the testicle • Sedation required to reduce – Valeron – Ileo-inguinal block Inguinal Hernia - Strangulated hernia • May present with bowel obstruction • Hot, red, tender, oedematous • Do not attempt to reduce • Differential of acute scrotum, but unable to get above mass • Urgent surgery • Bowel and testicular ischaemia and necrosis common Inguinal Hernia- Management • Hydroceles may gradually resolve over the first year • Persisting hydroceles: surgery • Hydroceles in older children may follow trauma, inflammation or tumours of the testis –manage the underlying condition • Fluid hernias: operate • Bowel containing hernias: surgery on next available list – warn parents of complications • Incarcerated hernias: reduce, operated before discharge • Strangulated hernias: resuscitate, urgent surgery Inguinal Hernia - Surgery • • Hernia, hydrocele fluid hernia can be done as an outpatient surgery, which is safe, effective, and well tolerated General anaesthetic – Caudal block with sedation • • Skin crease incision. Inguinal canal opened. Ilioinguinal and iliohypogastric nerve identified. Hernia sac identified, dissected from spermatic cord. High ligation of sac Limited role for laparoscopic as open performed through small incision in 20 to 30 minutes, associated with little morbidity, almost no mortality, and prompt return to normal activity Inguinal Hernia - Complications • Injury to the ilioinguinal nerve, vas deferens, and spermatic vessels, are uncommon after elective hernia repair • Bleeding is unusual • Wound infection (1%) • Scrotal haematoma • Postoperative hydrocele • Recurrent inguinal hernia (2%) Femoral Hernia Femoral hernias • Unusual in the paediatric age group • More common in girls • Usually present with a bulge below the groin crease Undescended Testis The Normal Descending Testis • The testicle begins to form just before the 2nd foetal month • By the 4th month it has migrated from the kidney to the to the internal inguinal ring • During month 7 the testicle, accompanied by a small peritoneal tube passes through internal ring, inguinal canal, and external ring to the scrotum • The mechanisms of descent are unknown – – – – – traction on testis by scrotal attachments differential growth of the body wall intra-abdominal pressure maturation of the epididymis multiple hormonal factors Undescended Testis Advantages of Scrotal Location • Scrotum is 2-3 oC cooler than core important for development of normal post pubertal testicular structure and sperm production • Cosmetic, psychological advantage • Less amenable to injury • The most common solid tumour in males age puberty to 40 yrs is testicular cancer, scrotal testes can be easily monitored Undescended Testis - Presentation • Incidence is 3-5% in full term boys, 1.8% at 1yr • About 65% of the testicles typically descend by 9 months of age • Clinically an empty scrotum • Scrotal hypoplasia Undescended Testis - Classification • Testicular retraction: – Most common age 5-6 yrs, from 1-11 yrs, 80% of fully descended testes can withdraw and leave scrotum empty, due to hyperactive cremaster, variation of normal. If a testis can be milked down to bottom of scrotum, it is retractile -no further treatment needed Usually improves by puberty • Cannilicular testis: – Testicle located above the scrotum, but still outside the abdominal cavity (72%) • Intra-Abdominal testes: – Testicle located inside the abdominal cavity in a position along its pathway of natural descent (8%) • Ectopic testicle: – Testicle found in regions not in the usual pathway of descent. 5 major sites are perineum, femoral canal, superficial inguinal pouch, suprapubic area, and contralateral scrotal pouch • Absent testicle: – Can be bilateral, associated with in utero torsion, vascular insult, or agenesis (4%) Undescended Testis Undescended Testis - Imaging • Generally imaging is not reliable • Ultrasound can help identify a testicle located in the inguinal canal, but is of limited use for intra-abdominal testes • MRI and CT scan can be useful for intraabdominal testes, but they are often difficult to use on small children and have a high false negative rate Undescended Testis Management • Avoid intervention before 6 months of age possible spontaneous descent • Bilateral undescended testes: – Intersex (females with adrenal hyperplasia) should be ruled out by hormonal work-up. HCG stimulation test for testosterone response is performed. Patients with bilateral anorchia will have no response • Pharmacotherapy – Avoids anaesthesia. HCG stimulates Leydig cells to produce male hormones. The mechanism of action is unknown, success rates are as low as10%. HCG or GRH analogues for palpable high-scrotal position of the testis • Surgical Orchidopexy – Most will be performed around 1 year. – There is evidence that early damage to the germ cells that produce sperm begins at 6 months. Undescended Testis - Surgery • Retractile testis – no surgery, monitor annually • Cannilicular testis – exploration and orchidopexy via a hernia incision. After removal of the hernial sac, the testis is delivered into the scrotum and anchored in a sub-dartos pouch Undescended Testis Non Palpable testis: Laparoscopy • Vas and vessels exit abdominal cavity – groin exploration • Testis low in abdomen and mobile: A laparoscopically assisted orchidopexy is performed via a small opening in the scrotum • High Intra abdominal testis: The testicular artery is divided. Revascularization occurs and pexy to the scrotum is performed in a 2nd stage operation in 6 months • Very abnormal gonad: Biopsy Undescended Testis - Outcome • Complications: – Bleeding – Infection – Uncommon • Fertility: – is less likely to be normal in 40% of unilateral and 70% of bilateral undescended testes. Early orchidopexy should optimize this • Tumorgenesis: – 20-48 times more likely to undergo malignant degeneration. Orchidopexy does not alter the risk of malignant transformation. The incidence is also increased in the unaffected testis. At puberty, boys should be taught how to perform monthly testicular selfexaminations. Seminoma is most common Acute scrotum • Red, Hot, painful, tender • Pathology – – – – – – Torsion of Testis Torsion of appendix testis Orchitis / epidydimitis Strangulated hernia Idiopathic scrotal oedema Haematoma Acute scrotum Torsion - Neonatal/extra-vaginal - Intra-vaginal • Peak incidence: 13-14yrs • Left side more common • Sudden onset • Extremely tender • Often “trauma” history Acute scrotum Testicular torsion: • U/S may see torted vessels • Surgery should not be delayed • Surgical exploration is only definitive method Acute scrotum Appendix Testis torsion • ‘Appendix’ is embryonal remnant of Mullerian structures • Sudden to progressive onset • Small blue dot/mass • If diagnosis certain, can manage conservatively • Analgesics for a week • Surgery definitive Acute scrotum Epididymitis: relatively rare • Slower onset • Dysuria • Urinary tract abnormalities – 47% prepubertal – Ectopic vas deference,ureters – Urethral abnormalities. • Dipstix may be positive Acute scrotum Strangulated hernia • Clinically evident • Bowel obstruction • Cant get above mass • Don’t attempt reduction • Urgent surgery Acute scrotum Idiopathic Scrotal oedema • <10yr of age • Unclear etiology – Eosinophilia, angioneurotic oedema • Oedematous, generally not painful or tender • Extends to perineum, inguinal area and opposite side • USS: Thickening and oedema of the scrotal wall, hypervascularity of the scrotum, and normal appearance of the testes • Supportive management Acute scrotum Haematoma • Trauma history – straddle, kick • Bilateral • Ultrasound • Conservative Testicular Mass • • • • Primary testicular tumours Lymphoma TB Calcified meconium from intra uterine perforation • Calcified haematoma Testicular Tumors • 2% of Paediatric malignancy • 0.05 – 2/100 000 • Bimodal distribution – First 2 years – Young adult • 60-77% germ Cell • Ultrasound • Appropriate investigations Thank you Questions??
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