3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
Candidate mutations
200
100
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
3
5
10
20
30
40
50
60
70
Candidate mutations
A
400
5x
●
300
●
●
●
BC2F2
300
10x
●
100
●
●
15x
●
●
●
10x
●
●
●
●●●●
●●
20x
●
B
400
15x
25x
●●●●●
●
●
●
●●●●●
●●●●●
●
●
●
●●●●
●●
●
20x
●●●●●●
●
●
●
●●
●●●●
50x
●
●
●●●●
●
●
25x
●
●
●
●
●●
●●●
0
Number of genomes
75x
●
●
●
●
●●●●
0
50x
●
●●●●●●
●
●
●
●
●●
●●
100x
●
●
●
●
●
●
●●●
●
●
75x
200
●
●
●
●
●
●
●
●●
●
200x
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●●
●
●
●
100x
●
●●
●●
Number of genomes
BC3F2
5x
200x
●
●
●
●
●
●
●
●
●●
●