Integumentary System Chapter 5 p. 116-132 Skin Coloring Normal skin coloring is due to 3 pigments: 1) Hemoglobin: gives pinkish hue due to red blood cells 2) Melanin: melanocytes give variety of brown, tan, & black Amount determined by heredity & UV exposure 3) Carotene: yellowish pigment from egg yolks & orange vegetables Skin Markings Hemangiomas: “birthmarks;” patches of colored skin caused by benign tumors of skin capillaries Freckles & Moles: clusters of melanocytes; vary w/ heredity & UV exposure Friction Ridges: “fingerprints;” unique to EVERY person Flexion Creases & Lines: lines on palms formed after birth Skin Functions 1) Barrier Keratin: provides toughness & resists scratches Acid Mantle: sweat makes skin acidic to repel bacteria H2O barrier: keeps valuable H2O from being lost UV barrier: keeps UV from penetrating deep into body 2) Vit D Synthesis: UV rays needed to make vit D in the skin Skin Functions (con’t) 3) Cutaneous Absorption: small amts O2, CO2, & some chemicals & vitamins can be absorbed through skin 4) Sensory Functions: senses touch & temp. Sensitivity varies around body 5) Thermoregulation: A) Vasodilation & Vasocontriction Body can control amt blood in skin to prevent or increase cooling of blood B) Sweating: evaporation cools the skin ACCESSORY STRUCTURES 1. HAIR 2. NAILS 3. HAIR FOLLICLES 4. SEBACEOUS GLANDS 5. SWEAT GLANDS Hair Types Key difference in hair, skin, & nails is amt hard keratin ALL people have same # hair follicles Differences due to texture & amt pigmentation Types: Languno: fine, downy hair in unborn fetus Vellus: fine, downy hair in children Terminal: course, darker hair on head & body after puberty Hair Structure Bulb: consists of root & shaft (above skin) Medulla: airy core Cortex: ↑ keratinized cells Cuticle: outer scaly cells Receptors: sense hair movement Arrector Pili muscles: make hair stand up when cold or scared Hair Texture & Color Texture due to cross-sectional appearance Straight: appears round Wavy: appears oval Curly: appears flat Color due to pigments Brown/Black: ↑ amt melanin Blond: ↓ amt melanin Red: tricosiderin pigment White: air in medulla & no pigments Gray: mix of white & pigmented Hair Growth Growth due to mitosis in stratum basale of epithelial root sheath (outer layer) Grows avg of 1mm/3days; Lose 10-100 strands daily Growth Abnormalities: Alopecia: thinning or loss of hair due to stress, fever, or disease Pattern Baldness: loss occurs only in certain areas due to heredity (X-linked trait) Hirsutism: excessive hairiness in women & children due to hormones Nails Derived from stratum corneum Contain ↑ amts hard keratin Structure: Nail Matrix: growth zone underneath skin Nail Plate: visible area Grow approx. 1mm/week Nail Abnormalities: Iron deficiency: cause flat or concave nails Hypoxemia (↓ O2): cause “clubbed” nails Skin Glands 1) Sweat Glands Merocrine Glands: produce sweat throughout body Apocrine Glands: in pubic area; give off scent after puberty 2) Sebaceous Glands: produce sebum (oil) in hair follicle 3) Ceruminous Glands: produce cerumen (ear wax) in ear canal 4) Mammary Glands: produce milk in females when pregnant Skin Diseases (see Table 7.4) 1) Acne: follicle plugged w/ bacteria 2) Eczema: itchy red lesions caused by allergies 3) Ring Worm: fungal infection of warm, moist area (“athletes foot”) 4) Warts: benign tumors caused by HPV virus; spread thru touch Skin Cancer ALL caused by UV radiation 1) Basal Cell Carcinoma: most common form; easily treatable 2) Squamous Cell Carcinoma: cancer of keratinocytes 3) Malignant Melanoma: found in moles; most deadly and fastspreading (metastisized) Skin Burns May cause death due to fluid loss, infection, & toxic chemicals from dead tissue Degrees: 1st: little redness & pain (most sunburns) 2nd: damage to epidermis & dermis (blistering) 3rd: complete destruction of skin (requires grafting) Treatment: fluid replacement, infection control, skin replacement (grafting)
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