Research Report 2O11-2O12 Division of Health Sciences
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Research Report
2O11-2O12
DIVISION OF HEALTH SCIENCES
1
RESEARCH REPORT 2011/2012
Research Report
2O11-2O12
DIVISION OF HEALTH SCIENCES
Cover photo: Professor Christine Winterbourn (Pathology, University of Otago, Christchurch) was awarded
New Zealand’s top science honour in 2011, the Royal Society of New Zealand’s Rutherford Medal.
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RESEARCH REPORT 2011/2012
FROM THE PRO-VICE-CHANCELLOR
Tënä koutou kätoa. Welcome to the 2011-2012 Research Report for the Division of Health Sciences, University of Otago. The
Division has an enviable reputation for research excellence and innovation, and we are proud to showcase our many and
varied achievements in this report.
The past two years have been both a challenging and an exciting period for the Division. They have been particularly difficult
years for colleagues on our Christchurch campus. The disruptions caused by the Canterbury earthquakes have been severe
but our staff and students have shown enormous resilience and tenacity and have continued to excel on all levels despite
the difficulties. As a testament to this, Professor Christine Winterbourn from the Christchurch campus was awarded New
Zealand’s highest science honour in 2011, the Royal Society’s Rutherford Medal. We congratulate Christine and wish all our
Christchurch staff and students the very best in their journey to full recovery
2011-2012 was also a period of significant growth and achievement for the Division. Once again our staff secured the lion’s
share of funding from New Zealand’s major funders in the health and science sectors including the Health Research Council,
and the Marsden fund. This funding supports the Division’s ground-breaking research which underpins many advances in
health policy and practice and the understanding of health and disease, both here in New Zealand, and globally.
Our staff are leaders in the fields of cancer genetics, mental health, neuroscience, infectious disease, public health, Mäori
health, cardiovascular disease, lifecourse research, and oral health. The depth and breadth of research expertise in the Division
means that research informs our teaching across all aspects of health professional training. Our students are taught by
academics and clinicians who are at the forefront of new knowledge, and who are closely integrated into the health workforce.
In this manner, we believe we are laying the foundations for the next generation of health research leaders in New Zealand.
I am sure that no matter what your area of expertise, you will find much of interest in these pages, and I encourage you to
contact us if you would like to know more.
Professor Peter Crampton
Pro-Vice-Chancellor Division of Health Sciences
University of Otago
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RESEARCH REPORT 2011/2012
CONTENTS
FROM THE PRO-VICE CHANCELLOR
2
EXECUTIVE SUMMARY
5
NOTES ON HOW THESE DATA ARE PRESENTED
6
ADDITIONAL SOURCES OF RESEARCH RELATED INFORMATION
6
THE DIVISION AT A GLANCE 7
RESEARCH HIGHLIGHTS 2011-2012
10
COMMERCIALISATION AND ENGAGEMENT WITH INDUSTRY
18
RESEARCH CENTRES AND THEMES
19
Mäori HEALTH RESEARCH
24
SCHOOLS AND DEPARTMENTS
26
BIOETHICS CENTRE
26
FACULTY OF DENTISTRY27
Department of Oral Diagnostic and Surgical Sciences 27
Department of Oral Rehabilitation29
Department of Oral Sciences
30
FACULTY OF MEDICINE33
OTAGO SCHOOL OF MEDICAL SCIENCES
33
Department of Anatomy
33
Department of Biochemistry
37
Department of Microbiology and Immunology41
Department of Pharmacology and Toxicology
44
Department of Physiology
46
DUNEDIN SCHOOL OF MEDICINE
49
Department of General Practice and Rural Health
49
Department of Medicine
51
Department of Pathology54
Department of Preventive and Social Medicine57
Department of Psychological Medicine
61
Department of Surgical Sciences
62
Department of Women’s and Children’s Health
65
UNIVERSITY OF OTAGO, CHRISTCHURCH68
Department of Anaesthesia68
Department of Medicine69
Department of Obstetrics and Gynaecology72
Department of Orthopaedic Surgery and Musculoskeletal Medicine.74
Department of Paediatrics
76
Department of Pathology78
Department of Psychological Medicine
81
Department of Public Health and General Practice
83
Department of Radiology and the Centre for Bioengineering84
Department of Surgery
85
Centre for Postgraduate Nursing Studies
87
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RESEARCH REPORT 2011/2012
UNIVERSITY OF OTAGO, WELLINGTON
88
Department of Medicine88
Department of Obstetrics and Gynaecology90
Department of Paediatrics and Child Health91
Department of Pathology and Molecular Medicine93
Department of Primary Health Care and General Practice94
Department of Psychological Medicine
96
Department of Public Health97
Department of Radiation Therapy100
Department of Surgery and Anaesthesia
102
SCHOOL OF PHARMACY
103
SCHOOL OF PHYSIOTHERAPY
106
RESEARCH FACILITIES AND SUPPORT SERVICES107
RESEARCH AND ENTERPRISE OFFICE
110
APPENDIX 1: PUBLICATIONS BY SCHOOL AND DEPARTMENT FOR 2011 - 2012
111
Professor Allan Herbison of the Centre for Neuroendocrinology was the recipient of the University of Otago’s 2011 Distinguished Research Medal
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RESEARCH REPORT 2011/2012
EXECUTIVE SUMMARY
•
The Division of Health Sciences is a research intensive Division with the highest overall annual research income within the
University.
•
The Division incorporates three campuses (Dunedin, Christchurch and Wellington) and comprises the following Schools
and Faculties:
Faculty of Dentistry
Faculty of Medicine
Otago School of Medical Sciences
Dunedin School of Medicine
University of Otago, Christchurch
University of Otago, Wellington
School of Pharmacy
School of Physiotherapy
Bioethics Centre
•
The University of Otago has established fourteen Research Centres and fifteen Research Themes for which the University
is pre-eminent and to which it gives particular recognition and support. Researchers within the Division of Health
Sciences are leaders of nine of the Research Centres and nine of the Research Themes.
•
All Schools and Faculties have a strong research focus as evidenced by their successes in securing external income ($130
million in 2011-12), their high numbers of postgraduate students (approaching 1300 in 2012), their quality research
outputs, and the many and varied honours and scholarships awarded to their staff and students.
•
The Division strongly encourages and supports the dissemination and commercialisation of research results.
•
The Division boasts extensive research support services including state-of-the-art research facilities and equipment,
training opportunities, and staff expertise.
•
The Division operates a Research Committee which is responsible for the dissemination of postdoctoral fellowships
and funding as well as having a mentoring role for researchers. Research in the Division is further supported by the
University’s Research and Enterprise Office which is the point of liaison between researchers and funding bodies.
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RESEARCH REPORT 2011/2012
NOTES ON HOW THESE DATA ARE PRESENTED
This report contains information on the research activities of the Division of Health Sciences at the University of Otago, for
the period 2011-2012.
The data contained within the report have been sourced from the University of Otago’s Research and Enterprise Database,
and from departments and departmental websites. Every attempt has been made to ensure that this report is as complete
and as accurate as possible, but given the diversity of activities and interests within the Division, there may be omissions or
inaccuracies for which we apologise.
Things to note:
•
Research contracts have been attributed to the home department of the principal investigator. Where there were multiple
principal investigators on a given contract it is acknowledged that this will duplicate the listing of a small number of
contracts in this report.
•
In a number of cases contracts straddled departments and it is unfortunate that this report is unable to give credit to coinvestigators who, while not listed here, did nevertheless contribute to securing funding.
•
This report lists details of external grants that were awarded in 2011 and 2012. A significant number of grants awarded
prior to 2011 were also active throughout some, or all, of this period. Information about these earlier grants is available in
earlier reports: www.otago.ac.nz/healthsciences/research/reports/index.html
•
Publications have been listed under the department of each author and co-author, meaning that some publications will be
listed more than once.
ADDITIONAL SOURCES OF RESEARCH RELATED INFORMATION
The Division of Health Sciences research website:
www.otago.ac.nz/healthsciences/research/index.html
Research Office, University of Otago, Christchurch:
www.otago.ac.nz/christchurch/research/researchoffice/
Research Office, University of Otago, Wellington:
www.otago.ac.nz/wellington/research/researchoffice/index.html
Health Research South, Dunedin School of Medicine
http://dnmeds.otago.ac.nz/research
Research and Enterprise Office, University of Otago:
www.otago.ac.nz/research/index.html
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RESEARCH REPORT 2011/2012
THE DIVISION AT A GLANCE
Staff and Student Information
Equivalent Full-time Students*
2011
2012
Total 5,761
5,815
Undergraduate 4,524
4,528
Postgraduate 1,237
1,287
PhD
418
424
Masters (Research)
139
163
Full-time Equivalent Staff
Academic and Research Only Staff
826
812
General Staff
691
669
Staff Head Counts
Academic and Research Only Staff
General Staff
* Includes Summer School
External Research Contract Income in $Million Per Annum
1,105
1,112
813
797
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RESEARCH REPORT 2011/2012
Funding Sources 2011-2012
Research Outputs
20082009201020112012
Journal Articles
11941263134815901598
All Publications
25212810280631793188
University of Otago Scholarships Awarded
20082009201020112012*
PhD Scholarship 6665909572
Masters Award
1013153015
*The decrease in number of scholarships awarded in 2012 reflects a decrease in the total number of scholarships awarded across
the University
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RESEARCH REPORT 2011/2012
Headcount of PhD/DClinDent and Masters by Research* Students
*Masters by Research includes only Masters degrees where students undertake a significant research project and write a research thesis
Canterbury Earthquakes
The 10,000 or so earthquakes that have struck the Canterbury region since September 2010 have caused huge disruption to
the lives of all Cantabrians, including staff and students from our University of Otago, Christchurch campus. The University’s
main 10-level building adjacent to the Christchurch hospital suffered substantial damage and was deemed uninhabitable.
Dislodged research teams were taken in and housed by neighbouring institutions, while others found makeshift space in a
rented warehouse and many others worked from home.
Despite the disruptions and stressors staff and students continued to excel. Staff successfully delivered a full medical
curriculum and maintained world class standards in research. A highlight was Professor Christine Winterbourn’s receipt of
New Zealand’s highest science honour in 2011, the Royal Society’s Rutherford Medal. Christchurch medical students averaged
the same marks as their Dunedin and Wellington counterparts – an incredible achievement given the trying circumstances
they were working under.
As this Report was being compiled, staff and students were moving back into their earthquake-strengthened main building almost a full two years after it was closed. This happened just in time for their 40 Year Anniversary celebrations. The Division
would like to thank all of our Christchurch staff and students for their amazing resilience and accomplishments over the past
two years. We wish them all the very best for the road ahead.
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RESEARCH REPORT 2011/2012
RESEARCH HIGHLIGHTS 2011-2012
Research Performance Indicators
~ External Research Contract Income: The Division’s external research contract income was $68 million in 2011 and $63
million in 2012.
~ Research Outputs: Our researchers published extensively with 3179 research outputs in 2011 and 3188 in 2012.
~ Health Research Council Funding Success: The University of Otago received more Health Research Council of New Zealand
funding than any other institution in both 2011 and 2012. Divisional researchers received approximately 37% of the total
funds allocated in the 2011 round and 41% in the 2012 round. One new Programme and two Programme extensions were
awarded in 2012 and one new Programme and three extensions in 2011, all of which were awarded to researchers within
the Division.
~ Marsden Funding Success: Once again the University of Otago was awarded the greatest percentage of the total national
Marsden pool in both 2011 and 2012.
~ MBIE Funding: In 2012, the University of Otago was awarded significant funding from the Ministry of Business
Innovation and Employment’s newly introduced Science Investment Scheme, with the Division securing approximately
$12.6 million of the $27.6 million awarded to the University.
~ The Division published 16 papers in prestigious Nature journals in 2011-2012.
~ Professorial Appointments: Twelve professors were either newly appointed or promoted within the Division in each of
2011 and 2012.
Awards and Accolades
~ Rutherford Medal
Professor Christine Winterbourn (University of Otago, Christchurch) was awarded New Zealand’s top science honour,
the Royal Society of New Zealand’s 2011 Rutherford Medal. This was the second year in a row that one of our staff was
awarded this medal and Professor Winterbourn is the first woman to win this award.
New Zealand’s top science prize the Rutherford medal was awarded to Professor Christine Winterbourn (University of Otago, Christchurch) in 2011.
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RESEARCH REPORT 2011/2012
~ Liley Medal
Associate Professor Chris Pemberton (University of Otago, Christchurch) was the recipient of the 2011 Liley Medal from
the Health Research Council of New Zealand.
~ Royal Society Fellowships
Professor Gerald Tannock (Microbiology and Immunology) was elected to a Fellowship of the Royal Society of New Zealand
in 2011. Three staff members received this honour in 2012: Professor Brett Delahunt (University of Otago, Wellington),
Professor Frank Griffin (Microbiology and Immunology) and Professor Tony Kettle (University of Otago, Christchurch).
~
New Zealand Honours
Companion of the New Zealand Order of Merit (CNZM)
Professor Warren Tate (Biochemistry) for services to science
Professor Christine Winterbourn (University of Otago, Christchurch) for services to science
Officer of the New Zealand Order of Merit (ONZM)
Professor Michael Ardagh (University of Otago, Christchurch) for services to emergency medicine
A/P David Lamb (University of Otago, Wellington) for services to health
Professor Jean-Claude Theis (Dunedin School of Medicine) for services to medicine
Member of the New Zealand Order of Merit (MNZM)
Professor John Carter (University of Otago, Wellington) for services to medicine
~ James Cook Fellowships
Professor Greg Cook (Microbiology and Immunology) and Professor Lisa Matisoo-Smith (Anatomy) received prestigious
James Cook Research Fellowships from the Royal Society of New Zealand in 2011 and 2012, respectively.
Professor Lisa Matisoo-Smith received a prestigious James Cook Research Fellowship in 2012 from the Royal Society of New Zealand.
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RESEARCH REPORT 2011/2012
~ Rutherford Discovery Fellowships
A number of staff were awarded Rutherford Discovery Fellowships from the Royal Society of New Zealand. In 2012: Dr
Peter Mace (Biochemistry) and Dr Tim Woodfield (Orthopaedics and Musculoskeletal Medicine, UOC). In 2011: Dr Peter
Fineran (Microbiology and Immunology) and Dr Wayne Patrick (Biochemistry).
~ Distinguished Research Medal
In 2011, the University of Otago awarded its Distinguished Research Medal to Professor Allan Herbison of the Department
of Physiology.
~ Rowheath Trust Award and Carl Smith Medal
Professor Lisa Stamp (Medicine UOC) was awarded the 2012 University of Otago’s Rowheath Trust Award and Carl
Smith Medal. In 2011, Associate Professor Richard Troughton (Medicine UOC) received this award. This medal provides
recognition for outstanding research performance by Early Career Staff.
~ University of Otago Early Career Awards:
All four University of Otago Early Career Awards went to Divisional researchers in 2012: Drs Sian Halcrow, Michael
Knapp and Andrew Clarkson (all from the Department of Anatomy) and Associate Professor Haxby Abbot (Dunedin
School of Medicine). In 2011, Dr Clare Strachan (Pharmacy), Dr Peter Fineran (Microbiology and Immunology) and Dr
Shieak Tzeng (University of Otago, Wellington) received the awards.
Drs Sian Halcrow, Andrew Clarkson, Michael Knapp and Associate Professor Haxby Abbott were awarded University of Otago Early Career Awards in 2012.
~ Prime Minister’s Supreme Tertiary Teaching Award
Dr Rhiannon Braund from the School of Pharmacy received the Prime Minister’s Supreme Award for Tertiary Teaching
Excellence in 2012.
~ L’Oreal For Women in Science Fellowship
Dr Suetonia Palmer (Medicine, University of Otago Christchurch) became the first New Zealander to win a L’Oreal For
Women in Science Fellowship. This was awarded for achievements in improving the treatment of people with chronic
kidney disease.
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RESEARCH REPORT 2011/2012
~ Harkness Fellowship
In 2011, Dr Sarah Derrett (Department of Preventive and Social Medicine) was a recipient of the Commonwealth Fund’s
Harkness Fellowship in Health Care Policy and Practice.
~ Professor Greg Cook (Microbiology and Immunology) had a bacterium named after him in 2011. Amphibacillus cookii
was so named by one of Professor Cook’s international colleagues to acknowledge his contributions to the microbiology
and bioenergetics of extremophilic bacteria.
Research Outcomes
~ A child’s self-control predicts future health
The Dunedin Multidisciplinary Health and Development Study has revealed that young children’s self-control skills,
such as conscientiousness, self-discipline and perseverance, predict their health, wealth and criminal history in later life,
regardless of IQ or social background. The findings suggest that even small improvements in self-control for children and
adolescents could yield important reductions in healthcare costs, welfare dependency and crime to the nation.
~ Trends in cancer survival and inequalities
The HRC funded Cancer Trends study based in the Department of Public Health, University of Otago, Wellington has
shown that cancer survival is increasing in New Zealand but inequalities in survival remain between ethnic groups.
The death rate among those diagnosed with cancer has reduced on average by 26% every decade since 1991. However,
differences in survival rates between Mäori and non-Mäori have not decreased over time. A major current challenge for
the health sector is how to promote even greater gains in survival for Mäori so that the gaps close. This research will assist
policy makers and health planners to accurately determine what future interventions will provide the highest benefit for
the health dollar and, thus, better patient survival.
Dr Matthew Soeberg, Associate Professor Diana Sarfati and Professor Tony Blakely are investigating trends in cancer survival and inequalities in New Zealand
~ Encouraging news for heart patients
A study by the Christchurch Heart Institute has shown for the first time that inheriting gene variants that increase the risk
of developing heart disease does not necessarily mean an individual is going to have a reduced life expectancy if he or she
suffers a heart attack. However, those that carried the gene variants tended to develop heart disease at a younger age. The
group is now undertaking a new project called the ‘The Family Heart Study’ examining specific genetic risk factors that
contribute to early coronary heart disease in New Zealand – a crucial study given that heart disease is the leading cause of
death in this country.
~ Cancer and the PAX8 gene
Professor Mike Eccles from the Dunedin School of Medicine has shown that PAX genes - members of a small family of genes
that play important roles in embryonic development – also allow cancer cells to grow and divide in adult tissues. The use
of molecular techniques to ‘silence’ the PAX8 gene in cancer cells halted cell division, leading to a state of senescence, and
ultimately, cell death. The findings suggest that PAX8 could be a good target for the development of future cancer therapies.
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RESEARCH REPORT 2011/2012
~ Breastfeeding protects against asthma
A comprehensive six year study by the Departments of Paediatrics at the University of Otago in Christchurch and Wellington
has shown that breastfeeding has a clear protective affect against children developing asthma or wheezing up to six years
of age. Prior to the publication of these findings in 2011, there had been much debate over this issue in the literature. New
Zealand has the second highest prevalence of asthma in the world, so these findings have significant health care implications.
~ Immunising against pneumococcal disease
Professor Philip Hill, Director of the University’s Centre for International Health has found that vaccinating young
children in Africa against pneumococcus may help protect entire communities from the deadly infections this bacterium
can cause. Randomised controlled trials involving 21 villages in Gambia showed that vaccinations in young children
resulted in reduced nasal carriage of the bacterium under investigation, not only in vaccinated children, but also in older
children and adults. Each year pneumococcal disease kills an estimated 800,000 children under five so this finding could
be of immense benefit to third world nations.
~ Newborn infection study
Professor Brian Darlow and colleagues from the University of Otago, Christchurch have played a vital role in a world wide
study investigating the usefulness of immune globulin treatment for infants with infections. Earlier research had suggested
that immune globulin treatment reduced deaths, but the new study involving almost 3500 babies in nine countries has
shown that this is not the case. Immune globulin is an expensive product derived from human blood with each treatment
costing more then $1000. This finding has the potential to save the New Zealand health system $200,000 per annum on
unnecessary treatments.
~ Reduced rates of campylobacter infection
Rates of campylobacter infection in New Zealand dropped by half following the introduction of nationwide interventions
to reduce campylobacter contamination of fresh chicken meat. The tighter regulations were introduced in response to
research carried out by Professor Michael Baker and colleagues from the Department of Public Health, University of Otago,
Wellington. These researchers confirmed the link between contaminated chicken and the high rate of campylobacteriosis in
this country, leading to savings of an estimated $60 million annually in productivity and health care costs.
Professor Michael Baker from the University of Otago, Wellington has worked extensively on the surveillance, investigation and control of infectious disease in New Zealand.
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RESEARCH REPORT 2011/2012
~ Working towards new anti-inflammatory drugs
Professor Tony Kettle from the University of Otago, Christchurch has been working on the development of safe and
effective drugs that target chlorine bleach, a toxic chemical produced during inflammation in many diseases. The research
has been carried out in collaboration with the pharmaceutical company AstraZeneca. The successful development of new
drugs to combat the painful condition of inflammation would benefit those suffering from conditions such as rheumatoid
arthritis, cystic fibrosis and emphysema.
~ Silicone dressings for skin reactions following radiation therapy
Eighty per cent of women undergoing radiation therapy for breast cancer experience skin reactions as a result of the
treatment. Clinical trials led by Dr Patries Herst from the University of Otago, Wellington have found that siliconebased Mepilex Lite dressings are more effective at decreasing painful skin reactions following radiation therapy than
conventional treatments. It is hoped that these dressings will become part of a standard skin care regimen in radiation
therapy departments throughout New Zealand in the near future.
Events
~ Divisional Research Forum
The Division runs an annual Research Forum to showcase the cutting edge research being undertaken within its Schools.
In 2011, the theme was ‘Innovation through Collaboration’ and in 2012 it was ‘Health Matters: Research Excellence at
Otago. Over 100 researchers and students attend the Forum in any given year.
~ National Health Research Roadshows
The Division has been working with the University of Auckland to increase the profile of health research in New Zealand by
running a series of roadshows at Parliament and in provincial centres. Roadshows highlighting cancer research were held at
Parliament, Tauranga and Nelson in 2012. Future roadshows will feature women’s and children’s health and heart disease.
~ International Cancer Symposium
The University of Otago, Wellington hosted the inaugural International Cancer Symposium in February 2011. The week long
Symposium attracted over 80 speakers from the USA, the United Kingdom, Australia and New Zealand including a number
of staff from the renowned Mayo Clinic in the USA. Sessions covered lung, haematologic and gastrointestinal cancers,
melanoma, palliative/end of life care, scientific advances and the controversial role of tobacco control in cancer prevention.
~ Queenstown Research Week
Divisional researchers were once again heavily involved in the organisation of the 2011 and 2012 Queenstown Research
Week. They had major input into the Medical Sciences Congress, the Australasian Winter Conference on Brain Research
and a number of the Queenstown Molecular Biology Satellite Meetings including QMB Genetics and QMB Cancer Biology.
Queenstown Research week is one of the largest annual conferences in New Zealand with over 700 delegates attending.
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RESEARCH REPORT 2011/2012
Appointments
~ A leading Belgian neurosurgeon and brain researcher, Professor Dirk De Ridder, was appointed as the inaugural
Neurological Foundation Professor of Neurosurgery within the Department of Surgical Sciences DSM in 2012. Professor
De Ridder will spend half of his time as a neurosurgeon at Dunedin Hospital and the other half undertaking research
and teaching. Mr Reuben Johnson was also recruited to the department as a Senior Lecturer and a consultant at Dunedin
Hospital. The two appointments are an invaluable addition to the Division’s existing body of world-leading researchers
working in the neurosciences.
~ In 2011, Professor John Crump was appointed as the McKinlay Professor of Global Health within the Centre for
International Health, Department of Preventive and Social Medicine. Professor Crump has a distinguished international
reputation for his work on infectious diseases in Africa, where he headed a research centre in Tanzania in collaboration
with Duke University and where he also served as a medical epidemiologist with the CDC.
Professor John Crump was appointed as the McKinlay Professor of Global Health within the Centre for International Health in 2011.
~ Professor John McMillan was appointed in 2012 as the new Director of the Bioethics Centre. Professor McMillan’s
research interests are prioritising health care, research ethics, the philosophy and ethics of mental health, and methodology
in applied ethics. Prior to this appointment he was an Associate Professor in Ethics, Law and Professionalism at the
Flinders School of Medicine in Australia.
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RESEARCH REPORT 2011/2012
Equipment and Facilities
~ PC3 Facility
The Division installed a PC3 laboratory on the roof of the Microbiology and Immunology building in 2011. The facility
represents a significant advance as it now enables researchers to work directly on important human disease causing
infections and pathogens. It will facilitate work in virology, tuberculosis, and other pathogens being studied throughout
the University.
~ Cryo-Transmission Electron Microscope
The Department of Anatomy has purchased a new cryo-transmission electron microscope with electron tomography
capability. It will be installed in the Otago Centre for Electron Microscopy mid-2013. The new microscope is a JEOL JEM2200FS cryo-transmission electron microscope, costing just over $2 million. The purchase represents a significant leap
forward in ultrastructural capability within the Division.
Scholarships and Fellowships
~ The Division hosts a number of very successful Summer Research Scholarship programmes - 233 students undertook
summer research projects within the Division in 2011/12 and 214 in the summer of 2012/13.
~ The Division awarded nine Career Development Postdoctoral Fellowships during 2011/12. These Fellowships are
intended to support outstanding graduates to gain further experience in their chosen fields and to establish themselves as
independent researchers.
~ William Evans Fellowships
The Division hosted ten international researchers on William Evans Fellowships during 2011-12.
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RESEARCH REPORT 2011/2012
COMMERCIALISATION AND ENGAGEMENT WITH INDUSTRY
The Division actively promotes staff participation in applied research and encourages entrepreneurial activity. In 2011, an
Associate Dean Commercialisation, Professor Ian Tucker from the School of Pharmacy, was appointed to lead Divisional
activities in this area.
Since his appointment, Professor Tucker has facilitated a clarification of the University’s promotion criteria, so that successful
delivery in the commercialisation space is now explicitly rewarded in promotion rounds. In addition, he is working closely
with Otago Innovation and the University’s Research and Enterprise Office to provide training and mentorship for those staff
interested in engaging with industry or commercialising their research findings.
During 2011-12, eight international patents arising from Divisional research were filed in the areas of heart disease,
neuroscience, fertility, and wound healing among others.
Staff have also been very successful at attracting applied funding from the Ministry of Business Innovation and Employment
(MBIE), including over $12.6 million in programme and smart ideas funding during 2011-12. A number of staff have been
the primary research agents on MBIE’s Technology Transfer Vouchers, which are awarded directly to companies to work with
Universities on their innovation and business ideas.
Dr Greg Walker from the School of Pharmacy won the University of Otago’s 2012 Innovation Proof of Concept Award for his
invention of a prototype medical device which tackles the problem of serious complications of post-surgery bleeding. In 2011,
Dr Don Schwass from the School of Dentistry and Dr Carla Meledandri (Chemistry) won the award for their research into the
development of silver nanoparticle-based materials for treating dental caries.
Dr Don Schwass (Dentistry) and Dr Carla Meledandri (Chemistry) were the 2011 recipients of the Otago Proof of Concept Award.
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RESEARCH REPORT 2011/2012
RESEARCH CENTRES AND THEMES
Research Centres and Themes are areas of research and/or collaborative groups of researchers in which the University of
Otago is pre-eminent and to which it gives particular recognition and support. Researchers within the Division of Health
Sciences are leaders of a significant number of the University’s Research Themes and Centres. These are detailed below.
RESEARCH CENTRES
Centre for Neuroendocrinology
Director: Professor Allan Herbison, Department of Physiology, OSMS
Website: www.otago.ac.nz/neuroendocrinology
The Centre for Neuroendocrinology (CNE) is a world-leading research centre for understanding how the brain controls
hormone levels in the blood and how these hormones act back to influence brain function. It has more than 70 members
and nine principal investigators; four from the Department of Anatomy; four from the Department of Physiology and
one from Obstetrics and Gynaecology, University of Otago, Christchurch. The centre represents the largest cluster of
neuroendocrinology researchers in the Southern Hemisphere. CNE research leads the world in understanding the brain control of reproduction, ranging from fertility to pregnancy to
lactation. Research programmes also examine neuroendocrine stress responses and the brain control of fluid balance. A
wide range of cutting-edge neuroscience methodologies are utilised, ranging from molecular biology and transgenics to
electrophysiological, morphological, cell imaging and in vivo approaches.
Centre for Translational Cancer Research
Director: Professor Parry Guilford, Department of Biochemistry, OSMS
Website: www.ctcr.otago.ac.nz
The Centre for Translational Cancer Research (CTCR) combines major University of Otago research groups in cancer genetics
and cancer immunology with leading oncologists and surgeons. It currently consists of over 20 senior scientists and clinicians
from the University who cover most fundamental and clinical areas of cancer research. The Centre’s mission is to support
and conduct cancer research with an emphasis on studies that can be expected to improve cancer treatment in a relatively
short timeframe. CTCR projects range from drug development to immunotherapy and include diagnostic test design and
personalised medicine. The latter includes the development of simple tests that can be used to select the best chemotherapy
treatment for individual patients and other tests that predict an individual’s prognosis and the risk of treatment side-effects.
Christchurch Heart Institute
Director: Professor Mark Richards, Department of Medicine, University of Otago, Christchurch
Website: www.otago.ac.nz/christchurch/research/cardioendocrine
The Christchurch Heart Institute (formerly the Christchurch Cardioendocrine Research Centre) is New Zealand’s preeminent cardiovascular research centre. The Institute is at the international forefront of cutting edge advances in the diagnosis,
prediction and treatment of serious cardiovascular disease; from bench to bedside to community. The Centre’s focus has
been the exploration of diagnostic, prognostic and therapeutic innovation in common and dangerous cardiovascular
diseases including acute coronary syndromes, heart failure and hypertension. The institute is best known for its longstanding
leadership in the field of cardiovascular neurohormonal control. One example of its world-leading work is the development of
a blood test to diagnose and monitor heart failure. This test now saves the lives of hundreds of thousands of people each year.
Edgar National Centre for Diabetes and Obesity
Research
Directors: Professor Jim Mann, Associate Professor Rachael Taylor,
Department of Medicine, DSM
Website: www.otago.ac.nz/diabetes
The Edgar National Centre for Diabetes and Obesity Research
(ENCDOR) aims to find effective solutions for two major national
health problems that are also global health challenges; obesity and
diabetes. ENCDOR’s purpose is to promote collaborative cutting
edge research both nationally and internationally and involves
a range of disciplines, including nutrition, epidemiology, Mäori
health, biostatistics, public health, paediatrics, microbiology,
genetics and biochemistry. Projects range from investigation
of genetic profiling which might enable the identification of
individuals more likely to benefit from interventions, to exploration
of how policy and food marketing shape our behaviour, to
the public health and economic impact of different innovative
approaches to manage weight and diabetes risk at all stages of life
from birth to the elderly.
Professor Jim Mann (Edgar National Centre for Diabetes and Obesity Research)
and Dr Lisa Te Morenga (Human Nutrition) are conducting research into a
variety of dietary and lifestyle interventions designed to tackle diabetes.
20
RESEARCH REPORT 2011/2012
Genetics Otago
Director: Associate Professor Peter Dearden, Biochemistry, OSMS
Website: www.otago.ac.nz/genetics
Genetics Otago aims to connect with the public, media and policy makers to improve the understanding of genetics: to
provide a hub where genetics is demystified; where user-friendly information, teaching resources and comments from worldclass geneticists can be easily accessed, all the while supporting its members’ collaborative research projects. The Centre’s
multi-disciplinary platform of research is enormous, ranging across sciences, health sciences, humanities, law and ethics. Key
areas of strength are human disease; developmental, microbial, and evolutionary genetics; law; epigenetics; anthropology;
conservation; environment; applied genetics in animal and plant breeding; and bioinformatics. With more than 180 active
members across multiple disciplines, Genetics Otago’s core strength is primarily based within the University but also includes
members from AgResearch (Invermay) and commercial genetics-based companies in New Zealand.
National Centre for Lifecourse Research
Directors: Professor Richie Poulton, Dunedin Multidisciplinary Health and Development Research Unit, DSM;
Professor David Fergusson, Christchurch Health and Development Study, University of Otago, Christchurch
Website: www.lifecourse.ac.nz
The National Centre for Lifecourse Research (NCLR) conducts and applies high-quality lifecourse research that informs policy
and practice to improve the lives of New Zealanders. Headquartered at the University of Otago, the NCLR is an umbrella for
research collaborations between six of New Zealand’s eight universities and one Crown Research Institute. Internal partners
include the Dunedin Multidisciplinary Health and Development Research Unit; the Christchurch Health and Development
Study; and the Centre for Research on Children and Families. External partners include research groups from AUT, Victoria,
Massey, Waikato, and Auckland universities and Environmental Science & Research (ESR), Christchurch. The partners have a
long history of conducting lifecourse research of two main types: (i) etiological-developmental research aimed at informing
policy and practice (e.g. New Zealand’s two international renowned longitudinal studies); and (ii) intervention research,
including running and evaluating new interventions in the community.
New Zealand Centre for Sustainable Cities
Director: Professor Philippa Howden-Chapman, Department of Public Health, University of Otago, Wellington
Website: http://sustainablecities.org.nz
The New Zealand Centre for Sustainable Cities is an inter-disciplinary research centre dedicated to providing the research
base for innovative system solutions to the economic, social, environmental and cultural development of our cities. The health
and well-being of most of our population (87% of New Zealanders live in cities) is reliant on developing environments that
take into account the connections between housing, transport, energy, urban form, health and governance and other issues.
Centre partners include Auckland, Massey, Victoria, and Canterbury Universities and NIWA. The Centre aims to work in
local, regional and national partnerships to develop the tools to promote well-being and health through smarter economic
development, safer and more sustainable housing, transport and energy systems, and enhanced urban design.
Sir John Walsh Research Institute for Oral Health
Director: Professor Jules Kieser, Faculty of Dentistry
Website: http://dentistry.otago.ac.nz/research/sjwri
The Sir John Walsh Research Institute advances research and increases knowledge
for the improvement of oral health in New Zealand. Its four innovative, futurefocused, inter-connected research programmes cover the spectrum of oral health
research from the molecular level through biological systems to the health of
populations. These programmes are: Biomechanics and Oral Implantology; Dental
Epidemiology and Public Health; Molecular Microbiology; and Oral Molecular and
Immunopathology. The Institute is part of New Zealand’s only Faculty of Dentistry
and its members have well-established productive collaborations across the
University and with other institutions in New Zealand and world-wide. Among its
research objectives is the development of clinical research that translates discoveries
into measurable health improvements, and to maintain fundamental research that
underpins teaching.
Professor Jules Kieser is the Director of the Sir John
Walsh Research Institute within the Faculty of Dentistry.
21
RESEARCH REPORT 2011/2012
Webster Centre for Infectious Diseases
Director: Professor Kurt Krause: Department of Biochemistry, OSMS
Website: http://webstercentre.otago.ac.nz
The Webster Centre for Infectious Disease works to bring New Zealand scientists together to address important problems
in infectious diseases in New Zealand. Based in Dunedin, the Centre has engaged more than 60 experts in both human and
animal diseases from four universities and key Crown Research Institutes, including AgResearch, ESR and IRL. Previously
focused on molecular-based projects, the Centre has now expanded its mission to include clinical and population health
research as part of its core activities. As a result, the Centre now includes leaders in basic, clinical and epidemiological research. Among the many aspects of infectious diseases that the Centre investigates are bacterial drug resistance and evolution,
antimicrobial design, viral pathogenesis, genetics of disease susceptibility, vaccine design, immunology and host susceptibility,
diagnostics and clinical infectious diseases, and public health.
Brain Health Research Centre
Director: Professor Cliff Abraham, Department of Psychology
Website: www.otago.ac.nz/bhrc
Although the Brain Health Research Centre (BHRC) is not led by a member of the Division of Health Sciences, Divisional
staff have significant input into the Centre. The BHRC encompasses over 40 different research groups and clinicians dedicated
to producing cutting edge international research into the workings of the brain. Translating neuroscience discoveries into
real treatments for those suffering from neurological disorders is a top priority for the BHRC. Researchers and clinicians are
involved with all stages of research on the brain from puzzling out the basic mechanisms of how the brain works to finding
treatments that harness the brain’s restorative potential, and testing of innovative therapies. Using a broad range of expertise,
staff are working toward a better understanding of neurological disorders including Alzheimer’s and Parkinson’s diseases,
stroke, epilepsy, tinnitus and motor neuron disease.
RESEARCH THEMES
Arthritis Research Theme
Director: Professor Lisa Stamp, Department of Medicine, University of Otago, Christchurch
Website: www.otago.ac.nz/christchurch/research/arthritis
The arthritis research theme is a multidisciplinary group of researchers with an interest in arthritis research. Doctors treating
patients with arthritis face a number of clinical challenges. These include:
•
•
•
identifying patients at risk of developing arthritis
determining which people with arthritis are likely to have more severe disease and future disability
individualising treatment and medication to provide the best options for arthritis patients.
The aims of the Arthritis Research Theme are to strengthen research into arthritis within the University of Otago by
encouraging laboratory and clinical research into the many different forms of this condition, and to increase the profile of
arthritis and arthritis research within New Zealand.
Aspire 2025: Research for a Tobacco Free Aotearoa
Director: Professor Richard Edwards, Department of Public Health, University of Otago, Wellington
Website: http://aspire2025.org.nz
Aspire 2025 is a partnership between major New Zealand research groups carrying out research to help achieve the
Government’s goal of a tobacco-free Aotearoa by 2025. It brings together leading tobacco-free researchers and health service
groups in New Zealand and strengthens existing collaborations. Areas of research encompass all the main aspects of tobacco
control activity including smoking cessation support, policy and regulatory research, smoking among young people, smokefree
communications, Mäori health and tobacco use, Pasifika tobacco use, and research capacity development. Theme members
make use of a translational approach which links the findings from clinical trials, experimental and observational studies,
qualitative approaches with end-users of research, to ensure work contributes directly to reductions in smoking prevalence.
22
RESEARCH REPORT 2011/2012
Comparative and Cross Cultural Studies
Directors: Associate Professor Jing Bao-Nie, Bioethics Centre; Dr Jacob Edmond, Department of English; Associate Professor
Takashi Shogimen, Department of History and Art History
Website: www.otago.ac.nz/research/centres/otago033698.html
The research theme will develop innovative cross-disciplinary approaches to comparative and cross-cultural studies, and
offer an institutional nest to conduct and promote cutting-edge interdisciplinary research in the area. It aims to position the
University of Otago as an international leader in comparative and cross-cultural studies.
Our current age of globalisation is distinguished by the scale and frequency of its interactions among different cultures. Today
countries such as New Zealand and universities such as Otago must respond to increasingly diverse cultural perspectives,
including in its approaches to research. This Theme responds to that need. The central goal is to search for innovative
methodological and theoretical approaches to cross-cultural and comparative studies. A group of Otago staff members and
postgraduate students and leading international scholars in disciplines including anthropology, music, literature, history, art
history and theory, philosophy, psychology, theatre studies, medicine, bioethics and other academic discipline will collaborate
in this exploration.
Formulation and Delivery of Bioactives
Director: Professor Ian Tucker, School of Pharmacy
Bioactive materials such as drugs, vaccine antigens, pesticides and nutrients cannot be administered in pure form but must
be incorporated into biocompatible formulations which maintain the stability of the bioactive material and deliver it in a
suitable way to achieve optimal beneficial effects while minimising unwanted side effects. Thus, the science of formulation
and drug delivery has human, veterinary and agricultural applications. It combines physical chemistry, biology and materials
science to investigate physico-chemical properties of bioactives, excipients and formulations and behaviours of bioactives and
formulations in the biological environment in order to develop an underpinning science.
This science is the basis for design and manufacture of delivery systems with predictable behaviours. Work includes:
chemical and physical stability of drugs; pharmaceutics of the solid state; colloidal systems for delivery of drugs and antigens;
absorption of bioactives across biological membranes. These projects have fundamental, applied and developmental aspects.
Full Circle: MAori and Pacific Genetics of Health
Director: Associate Professor Tony Merriman, Department of Biochemistry, OSMS
The sequencing of the human genome in 2001 initiated a decade of rapid advance in understanding the impact of genetic
variation in the human genome on human disease. This, and the advent of new ‘next generation sequencing’ technologies that
enable identification of all variation in individual genomes, ensures that genetic approaches to human diseases will continue
to be prominent in health research.
Conducting Mäori- and Pacific-focused research requires consultation and on-going engagement with specific communities
and organisations. All aspects of research from initiating and conducting the research through to dissemination and
translation of the results must be undertaken in a manner consistent with cultural values and protocols. This represents
unique challenges. Appropriate processes need to be put in place to enable genomic scientists to fulfill obligations to Mäori
and Pacific communities, and to assist their engagement with these communities. The growth of Mäori and Pacific capability
in genetics is required.
The focus of this theme is on the strengthening of research with Mäori and Pacific communities (in New Zealand and the
South Pacific) on the genetics of health.
Gut Health Network
Director: Associate Professor Michael Schultz, Medicine, DSM
Website: www.guthealthnetwork.com
Recent research has suggested that the interaction of the bowel microflora with the intestinal immune system on a specific
genetic background plays a much more significant role in disease than previously anticipated. Many diseases have their origin
in the gut, not only inflammatory bowel diseases, but also certain rheumatological disorders, diabetes, obesity and potentially
many others.
The Gut Health Network is an initiative of the University of Otago and brings together national and international experts
from various fields and disciplines to collaboratively work on these health issues. Basic scientists in genetics, immunology,
microbiology and physiology have teamed up with gastroenterologists, paediatricians, rheumatologists and surgeons in a truly
bench to bedside approach.
23
RESEARCH REPORT 2011/2012
Health of Veterans, Serving Personnel and their Families
Director: Associate Professor David McBride, Department of Preventive and Social Medicine, DSM
Website: www.otago.ac.nz/veteranshealth
The theme is dedicated to producing high quality, interdisciplinary research focused on the health status and needs of
veterans, serving personnel, and their families. It is the result of a joint effort between the New Zealand Ministry of Defence
and the University of Otago.
The aim of the theme is to explore future ideas with the broadest possible grouping of researchers within the University,
initially around the interface between civilian and military health, and post-conflict re-integration of service people back into
their communities and families. In the longer term the theme intends to use the evolving platform of research activities to
develop an argument for Government funding as the ANZAC centenary approaches.
Many significant anniversaries will occur in the period 2014-18, including the 100th Anniversary of the Battle of the Somme.
The Australian National Commission for the ANZAC Centenary has recommended an Anzac Centre for the Study of Peace,
Conflict and War. The research theme intends to engage with this centre.
The Kidney in Health and Disease
Director: Professor Rob Walker, Department of Medicine, DSM
Website: http://kidney.otago.ac.nz/
The vision of this theme is to expand the collaborative network for kidney research, linking an understanding of the molecular
and cellular physiology of kidney function to the clinical application of therapies that prevent kidney injury or the progression
of kidney disease. This knowledge will lead to more focused interventions that will reduce the rapidly increasing incidence of
chronic kidney disease and the need for renal replacement therapy (dialysis and transplantation).
This theme involves researchers from the University’s medical schools in Christchurch and Dunedin and from departments in
the wider University. Strong links have been established between the researchers and nephrology colleagues at District Health
Boards throughout New Zealand, as well as with other research institutions nationally and internationally. The theme is now
one of the leading renal research consortiums in the Southern Hemisphere.
Otago International Health Research Network
Directors: Professor Philip Hill and Professor John Crump, Department of Preventive and Social Medicine, DSM
Website: http://dnmeds.otago.ac.nz/departments/psm/research/international_hlth/network
The Otago International Health Research Network, which is hosted by the Centre for International Health, fosters and builds
on collaborative links across the University to contribute to the understanding and improvement of health in under-resourced
countries. The Network includes approximately 50 researchers and their students across the four divisions of the University.
These researchers are conducting research across the world and are involved with major international health bodies such as
WHO, CDC Atlanta and the Gates Foundation.
The major research goals of the Network are to:
•
•
•
•
foster increased collaboration between researchers already doing health-related research in developing countries
monitor international health funding opportunities
facilitate the interaction between staff at the University of Otago and international health researchers from other countries
by hosting pre-eminent international health researchers at the university for seminars and symposia
identify new ways to develop the international health collaborations across the university
Oxygen Theme
Director: Professor Tony Kettle: Department of Pathology, University of Otago,
Christchurch
Website: www.otago.ac.nz/christchurch/research/freeradical
Free radicals are molecules that contain an unpaired electron. They are very reactive
chemicals and are being made all the time inside our bodies via reactions with
oxygen. Free radicals can cause damage, and we have antioxidants that provide
protection. However, free radicals also play important roles in health, helping to fight
infection and transmit signals.
Our mission is to discover what free radicals do inside the body, and how this
knowledge can be used to measure and treat human diseases. Members of the theme
are drawn from at least seven different departments, spread across three campuses,
and include biochemists, clinicians and nutritionists. Our research is focused on
diseases of both childhood and ageing, and antioxidants in health. It has potential
applications to cancer, heart disease, arthritis, neurodegenerative diseases, cystic
fibrosis, inflammatory bowel disease and infectious diseases.
Professor Tony Kettle from the Centre for Free Radical
Research is the Director of the Oxygen Theme.
24
RESEARCH REPORT 2011/2012
RANGAHAU HAUROA MAori
– MAori
HEALTH RESEARCH
The Divison has a strong focus on Mäori health research, with dedicated Mäori health research centres on all three campuses.
Areas of research include mental health, heart disease, health inequalities, indigenous health workforce issues, Mäori women’s
and children’s health, oral health, gout, diabetes, and indigenous health in the medical curriculum.
Over the past two years the success of the Division’s Mäori Health Workforce Development Unit has led to an increase in
the number of Mäori entering into the University of Otago’s health sciences professional and degree programmes. The unit
also provides support for successful degree completion and academic excellence, building the capability for these students to
proceed into the professions and to undertake postgraduate study and research.
- Te ROpU Rangahau Hauora MAori o NgAi Tahu – NgAi Tahu MAori Health Research Centre
Dunedin School of Medicine
Website: www.otago.ac.nz/dsm/ngaitahu
The Ngai Tahu Mäori Health Research Unit is a partnership between Te Runanga o Ngai Tahu and the Dunedin School of
Medicine of the University of Otago. The Unit collects, collates, interprets and publishes information, data and statistics on
Mäori health issues - an essential part of Mäori health development. The research focuses for the Unit are: hauora rangatahi
(young people’s health); hauora wahine (Mäori women’s health) and oranga niho (dental health).
The Unit has collaborative research projects with the Injury Prevention Research Unit and The Christchurch Health and
Development Study. The Unit also assists other research groups with aspects of Mäori health research that may be part of their
respective projects. A research highlight during 2011-12 was a project aimed at improving the oral health of Mäori children by trialling an
intervention in early childhood. This study was funded by an HRC grant of $2 million to Professor John Broughton who
directs the Ngäi Tahu Mäori Health Research Centre.
MAori and Indigenous Health Institute (MIHI)
University of Otago, Christchurch
Website: www.otago.ac.nz/christchurch/research/mihi
MIHI has had extensive experience in researching within Mäori communities. The Institute conducts research that assists with
an understanding of Mäori health and works to develop strategies that promote Mäori health gain. MIHI also has significant
input into the medical curriculum. The Institute’s recent research activities include:
Educating for Equity
The MIHI teaching team have been piloting a number of different approaches to teaching Mäori health content within the
current teaching curriculum. This work has received funding from the Health Research Council.
Hauora Manawa/Heart Health: the Community Heart Study
An important ongoing study is the Mäori Community Heart Study. This is a collaborative study with the Christchurch
Cardioendocrine Research Group and is investigating the full range of cardiac risk factors for Mäori within two community
settings. The project is also identifying objective markers (biochemical and cardiac imaging) for monitoring cardiovascular
disease risk in Mäori, and will document the implementation of treatment programmes, interventions, barriers to care and
outcomes for study participants.
Application of Meihana Model to Clinical Practice
This Ministry of Health funded project trialled the application of the Meihana Model to Clinical Practice within both a mental
health setting and a Mäori health provider setting. It explored how cultural confidence and clinical expertise can be fused to
produce better clinical outcomes for Mäori patients.
The place of indigenous health within a medical curriculum
This project formed the basis of a PhD project exploring the UOC site, and how indigenous health is placed and valued within
the undergraduate medical curriculum. It involved interviews with students, staff, systemic stakeholders, Mäori community
stakeholders and Mäori patients. It also explored indigenous health curriculum within five other medical schools (both
nationally and internationally).
25
RESEARCH REPORT 2011/2012
- Te ROpU Rangahau Hauora a Eru pOmare - Eru pOmare MAori Health Research Centre
University of Otago, Wellington
Website: www.otago.ac.nz/wellington/research/erupomare
Te Röpü Rangahau Hauora a Eru Pömare strives to create a Kaupapa Mäori space committed to improving Mäori health
outcomes and eliminating inequalities through quality science and ongoing theoretical development. It takes a rights-based
approach consistent with the Treaty of Waitangi, and is engaged with community through a spectrum of influence from
community development, policy advocacy, research dissemination and Mäori health.
Recent research projects include:
•
•
•
•
•
•
•
•
•
•
•
•
BreastScreen Aotearoa Mäori Monitoring
Educating for Equity (E4E)
E Hine – reducing barriers to care for pregnant Maori women under 20 years and their infants
Mauri Mahi, Mauri Ora – long term health effects of redundancy and unemployment
Oranga Waha – oral health research priorities for Mäori
Prisoner Health
Racism as a determinant of health
Rural Mäori Health
Seclusion of Mäori in adult mental health services
Unequal Impact: Mäori and non-Mäori cancer statistics
Unequal Treatment – the role of health services
Wahine Hauora – inequalities in uterine cancer
During 2011-12, two staff members received project funding from the HRC:
Associate Professor Beverley Lawton (Primary Health Care and General Practice). Diabetes: The impact of maternal care
disparities on Mäori mothers and infants. $1.192 million.
Dr Tristram Ingham (Medicine). Whiti Te Ra: The contribution of housing conditions to bronchiolitis disparities.
$1.157 million.
- Raukawa) directs the Eru Pomare
- Health Research Centre at the University of Otago, Wellington
Bridget Robson (Ngati
Maori
Bioethics
26
RESEARCH REPORT 2011/2012
SCHOOLS AND DEPARTMENTS
BIOETHICS CENTRE
Director of Centre: Professor John McMillan
Email: [email protected]
Website: www.bioethics.otago.ac.nz
The wide range of research projects and activities of the Centre aims to examine the conventional and novel moral dilemmas
arising from medical research, clinical settings, and advances brought about by life sciences and biotechnologies. Effort is
focused on exploring previously rarely-chartered areas and innovative conceptual and methodological approaches. The Centre
is committed to active engagements with social and public policy issues at local, national and international levels.
Major Areas of Research Strength
Neuroethics
The overlap between neuroscience and ethics creates problems involving neuroimaging and information use, moral aspects of
personhood and brain changes that explain behaviour or affect a person’s identity, and the ethical importance of consciousness.
Reproductive ethics
Ethical considerations in the use of reproductive technologies, and ethical issues arising from social policy in the area of
reproduction: IVF, surrogacy, pre-implantation genetic diagnosis, one-child policy in China.
Philosophy and mental health
Is there any such thing as mental disorder? If there is, what kind of thing is it? If coercion can sometimes be justified in
psychiatry, what are the circumstances? Exploring the conceptual status of psychotic hallucinations and delusions, and
whether psychiatry should be replaced by cognitive neuroscience.
Philosophy of medicine
The relationship between biomedical science and clinical practice, and whether diseases be regarded realistically, pragmatically
or as social constructs. The status of complementary and alternative medicine. What role should evidence-based medicine
have in medical decision making?
End of life
When should a human life be allowed to end, can a patient request aid in dying, is euthanasia permissible, are there states of
living that are worse than death? Should it always be a patient’s choice as to how and when his or her death occurs
Cross-cultural ethics
Mäori perspectives on genetic biotechnologies and health care, the nature of indigenous knowledge, medical ethics in China,
Confucian and Daoist perspectives on bioethics, Chinese voices on abortion, the ideology and ethics of China’s birth control
program, the ethics of population engineering in the east and west, Japan’s wartime medical atrocities and international
aftermath, the search for a transcultural bioethics.
External Grants Awarded 2011-2012
Year
2012
PI
Project Title
Funder
$*
A/P Jing-Bao Nie Patient-physician trust and mistrust in China
Harvard China Fund
142,000
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters †
2011
2012
119
1619
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Simon Walker
Exceptional PhD Thesis, University of Otago
27
RESEARCH REPORT 2011/2012
Sir John Walsh Research Institute
Director: Professor Jules Kieser
Email: [email protected]
Website: http://dentistry.otago.ac.nz/research/sjwri/index.html
The Sir John Walsh Research Institute (SJWRI) within the Faculty of Dentistry provides a focus for dental research within the
University and also within New Zealand. Research carried out in the Institute underpins the teaching of dentistry, its clinical
practice, and the identification of oral health related problems. The Institute draws together the research strengths within the
three departments within the Faculty and groups these into five major research themes:
•
•
•
•
•
Biomechanics and oral implantology
Dental epidemiology and public health
Education research
Molecular microbiology
Oral molecular and immunopathology
The SJWRI hosts a large number of postgraduate students undertaking the following qualifications:
Total Head Count
PhD
2011
2012
3735
DClinDent
5545
Masters†
1216
† thesis or dissertation students only
DEPARTMENT OF ORAL DIAGNOSTIC AND SURGICAL SCIENCES
Head of Department: Professor Robert Love
Email: [email protected]
Website: http://dentistry.otago.ac.nz/departments/odss.html
The Department of Oral Diagnostic and Surgical Sciences is organised into the disciplines of Oral and Maxillofacial Surgery,
Oral Medicine, Oral Radiography, Oral Pathology, Special Needs Dentistry, Clinical Pharmacology and Sedation, and General
Dental Practice. The main areas of research in the department are:
•
•
•
•
oral diseases and healing with particular interest in human and experimental epithelial hyperplasia, preneoplasia and
neoplasia (that may lead to oral cancers)
endodontic microbiology and the molecular mechanisms involved in bacterial invasion of dentine
the development of endodontic medicinal agents for root canal disinfection and their effects on bacteria and tissues culture
clinical research in endodontics, dental implantology, oral and maxillofacial surgery, trauma, and prosthodontics.
Major Areas of Research Strength
Endodontic microbiology
The study and practice of endodontics is aimed at preventing and treating pulp
and periapical disease. An understanding of the mechanisms of bacterial invasion
of dentine and the root canal system is central to these aims. Bacterial infection of
dentine has been recognised for over a century, but only recently has this research
group identified the mechanisms involved in colonisation. This should lead to
novel prophylactic and control treatments. Endodontic microbiological research
has focused on the effect of nutritional stress on bacterial invasion of dentine, and
identified that colonisation of dentinal tubules is dependent on an ideal nutritional
environment, with nutritionally stressed bacterial cells losing their ability to invade.
Oral and maxillofacial surgery
The discipline of Oral and Maxillofacial Surgery has a strong clinical research focus and
is involved with collaborative research within the department, Faculty and externally.
Particular areas of research interest include epidemiological studies of maxillofacial
injuries, oral and maxillofacial pathology and general practitioner experiences in
dealing with maxillofacial trauma. Clinical trials involving patients are also part of a
wider research focus and current studies continue to progress which include third molar
surgery, post-operative analgesics and dental implantology. A series of evidence based
systematic reviews of selected aspects of maxillofacial trauma management is being
developed. Expertise in ballistic and war injuries to the maxillofacial region has grown in
the department leading to a device being patented in the period.
Associate Professor Darryl Tong of the Faculty of
Dentistry is an oral and maxillofacial surgeon and
a member of the military, a combination that has
enabled him to develop expertise in the area of
ballistic and war injuries to the face.
Dentistry
FACULTY OF DENTISTRY
Dentistry
28
RESEARCH REPORT 2011/2012
Oral pathology
Research interests in oral pathology involve immunohistochemical and PCR studies looking at the expression of various
inflammatory processes in oral inflammatory lesions (e.g. periapical pathology, mucosal lichen planus) and oral malignancy
(squamous cell carcinoma) in order to better understand the pathological processes involved. Investigation of expression of
putative odontogenic-specific markers in odontogenic tumours and cysts is another research thread. We have recently begun a
collaborative study with other groups within the University exploring the use of saliva as a diagnostic medium for the detection
of human papilloma viruses. Epidemiological studies on pathology of the soft and hard tissues of the oral cavity and related
structures show that the prevalence and distribution of oral pathological lesions in the New Zealand population is comparable
to similar developed countries. A new focus on the linkages between oral health and autoimmune disease is being developed.
External Grants >$10,000 Awarded 2011-2012
Year
PI
2012
Prof Alison Rich Project Title
Funder
Do multifaceted admission processes predict
performance of students in two Australasian dental programmes?
Undergraduate Medicine
129,871
and Health Sciences Test
(UMAT) Board
2011
Dr Harsha De Silva
The role of Candida albicans in the
clinicopathological behaviour of potentially
malignant oral disorders
New Zealand Dental 15,000
Association Research
Foundation
2012
Prof Alison Rich
Endoplasmic reticulum stress and unfolded
protein response in the pathogenesis of oral
squamous cell carcinoma
New Zealand Dental
15,000
Association Research
Foundation
2012
Prof Alison Rich
How does submersion in a seawater
environment affect the retrieval of useful DNA from teeth?
New Zealand Dental 15,000
Association Research
Foundation
2012
Prof Alison Rich
Characterization of Th17 cells in oral mucosal New Zealand Dental
14,981
lichen planus using immunohistochemistry, Association Research
immunofluorescence and real-time reverse Foundation
transcriptase polymerase chain reaction
2012
Prof Alison Rich
Angiogenic factors in oral squamous cell carcinoma New Zealand Dental
Association Research
Foundation
$*
14,422
* GST exclusive
Commercial Contracts
Year Approved
Organisation
Downie Stewart
Total
4,000
Postgraduate Students
See the section on the SJWRI above for details of postgraduate student numbers.
Awards and Honours
Year Recipient
2011
Professor Alison Rich
Award
Researcher of the Year Award, Sir John Walsh Research Institute, University of Otago
RESEARCH REPORT 2011/2012
DEPARTMENT OF ORAL REHABILITATION
Head of Department: Professor Tom Kardos
Email: [email protected]
Website: http://dentistry.otago.ac.nz/departments/oralrehabilitation.html
Research undertaken within the Department of Oral Rehabilitation covers a diverse range of topics related to dental education
research, clinical cariology, endodontics, biomaterials, prosthodontics and dental technology. More specifically, research is
directed at the prevention and treatment of dental disease, the repair and replacement of teeth and their associate structures
affected by disease, trauma or wear, the restoration of form, function and appearance, mechanical testing and computer
modelling of the behaviour of dental tissues and biomaterials.
Major Areas of Research Strength
Oral biomechanics and biomaterials
Investigations focus on a range of mechanically mediated responses of dental materials and biological tissues, ranging
from the influence of mechanical forces on the stresses developed in the mandible to the stresses and failure mechanics of
restorations. This research has significant bearing on the design longevity and anticipated failure of implant-supported
structures. Major inroads have been made into the understanding of the stresses developed in craniofacial structures as a
consequence of biting forces. The use of CT-based images and computer modelling has enabled researchers to predict the
mechanics of failure of complex dental restorative systems. This will lead to a more rational design and selection of materials
for tooth restorations.
Oral implantology
Clinical and laboratory-based research relating to implant dentures and single-tooth implants is conducted. The aim is to
improve the oral health-related quality of life of the ageing population. The Department’s evidence-based treatment approach
of reducing the delay between oral implant placement and loading with the prosthesis is internationally recognised. Current
research aims to identify and quantify the pre-load stress developed on the peri-implant bone and prosthetic framework as a
result of misfit using a recently developed mandible replica.
Oral public health
There is a growing research focus in this area with an emphasis on caries prevention.
External Grants > $10,000 Awarded 2011-2012
Year
PI
Project Title
2011
Dr Lyndie Foster Page A novel approach to caries management in
New Zealand children
Funder
2011
Dr Lyndie Foster Page A novel approach to caries management in
children by resin infiltration
New Zealand Dental
54,587
Association Research
Foundation
2011
Dr Lihong He
Maurice and Phyllis
Paykel Trust
Development of multispectral imaging based
dental diagnostic devices
* GST exclusive
Commercial Contracts
Year Approved
Total
Organisation
DMG Dental Materials Gesellschaft
75,006
Postgraduate Students
See the section on the SJWRI above for details of postgraduate student numbers.
$*
Health Research Council 146,826
of New Zealand
10,000
Dentistry
29
30
RESEARCH REPORT 2011/2012
Dentistry
Awards and Honours
Year 2011
Recipient
Award
Dr Jonathan Broadbent
New Zealand Outstanding Young Dentist Award
2011
Dr Don Schwass
Otago Proof of Concept Award
2011
Dr Lyndie Foster Page
Award in Preventive and Community Dentistry, International Association for
Dental Research Australia and New Zealand Division 2011
Dr Neil Waddell
Research Publication Award, Sir John Walsh Research Institute,
University of Otago
DEPARTMENT OF ORAL SCIENCES
Head of Department: Professor Richard Cannon.
Email: [email protected]
Website: http://dentistry.otago.ac.nz/departments/oralsciences.html
Research conducted within the Department includes molecular microbiology, oral immunology, oral biology, dental anthropology,
tissue regeneration, craniofacial growth, implantology, clinical dentistry, public health dentistry and education research.
Major Areas of Research Strength
Dental epidemiology and public health
The Dental Epidemiology and Public Health Group investigates the oral health of populations, with particular attention
given to the natural history of dental disease and health through childhood, adolescence and adulthood. Collaborations with
two world-renowned projects are ongoing - the Dunedin Multidisciplinary Health and Development Study (a prospective
observational study of a cohort of New Zealanders born in 1972-73) and the South Australian Dental Longitudinal Study (a
prospective observational study of a cohort of older South Australians).
Forensic dentistry
Areas of research interest include: the biomechanics of wounding; marine decomposition; and bite marks and personal
identification. A key recent project has involved the bacteriological fingerprinting of bite marks, where the unique
streptococcal bacteria transferred by a bite may be used to identify offenders in sex crimes or child abuse. Another project of
note is the development of various models which reliably replicate blunt trauma impact events. An interdivisional research
project has been launched which is aimed at the admissibility of expert forensic evidence. The team consists of dental
researchers and others from the Faculty of Law, the School of Pharmacy, and the Dunedin School of Medicine.
Molecular microbiology
This research aims to study the microorganisms responsible for a range of oral diseases, to understand how the diseases
are caused, and to devise strategies to prevent them. Investigations are underway into how periodontal bacteria acquire the
haem they require for growth, as preventing this access may help prevent periodontal disease, and how bacteria colonise
and invade dentinal tubules, which can lead to endodontic infections. DNA sequencing technology is being used to analyse
the ‘metagenome’ associated with oral health and periodontal disease. Additional major areas of research include microbial
adhesion and oral fungi that cause mucosal and systemic infections, antifungal drug resistance and antifungal drug discovery.
Oral immunopathology
The main objective of this group is to explore the cellular and molecular basis of oral diseases, so as to improve their diagnosis
and treatment. Three major themes include: (i) periodontal diseases, (ii) oral mucosal disease including oral squamous cell
carcinoma, and (iii) tissue regeneration through the use of induced pluripotent stem cells. In terms of periodontal disease
the focus is on using the peripheral blood and salivary transcriptomes in the determination of susceptibility, the use of
metagenomics to determine the oral microbiota and epigenetics to determine the influence of environmental factors such
as smoking. The relationship with systemic diseases is also being investigated, as are the immunopathological mechanisms
underpinning oral mucosal disease. In collaboration with the University of Queensland, the group is conducting a five-year
longitudinal clinical study on the relationship between periodontal and cardiovascular diseases. This study has attracted over
$3 million in funding in recent years.
RESEARCH REPORT 2011/2012
External Grants > $10,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2011
Prof Murray Thomson A research project to improve oral health
Ministry of Health
230,332
self-care outcomes for at-risk adults
2011
Alison Meldrum
The interaction styles of dental therapists in the New Zealand Dental
26,473
Southern District Health Board area: Do their Association Research
interaction styles change if they are trained in Foundation
the Motivational Interviewing Approach?
2012
Dr Nicholas Heng
Oral bacterial profiling of children before and New Zealand Dental
23,477
after comprehensive restorative treatment for Association Research
severe early childhood caries
Foundation
2011
A/P Mary Cullinan
Bisphosphonate related osteonecrosis of the
jaw (BRONJ) and the role of osteoblasts
New Zealand Dental 22,211
Association Research
Foundation
2011
Otago Innovation Limited
Prof Richard Cannon
Pilot study for anti fungal drug discovery
17,052
2011
A/P Warwick Duncan
Electrospun cottonwool-like nanocomposites New Zealand Dental
15,000
for alveolar ridge preservation: An experimental Association Research
study in sheep
Foundation
2011
Prof Mauro Farella
Continuous measurement of salivary pH using New Zealand Dental 15,000
a novel indwelling wireless intraoral pH
Association Research
telemetry
Foundation
2012
A/P Warwick Duncan UMF manuka honey as a subgingival delivery
New Zealand Dental
15,000
device in the treatment of chronic periodontitis Association Research
Foundation
2011
Dr Dawn Coates
VEGF-A, RHOB and BMP-2 gene expression
regulation in bisphosphonate treated human
gingival fibroblasts 2011
Prof Richard Cannon Image analysis for dental research
New Zealand Dental
14,982
Association Research
Foundation
New Zealand Dental
Association Research
Foundation
14,845
2012
A/P Warwick Duncan
Could surface modification of titanium-
Wishbone Trust
zirconium alloy by anodisation improve
osseointegration?
2012
Dr Trudy Milne
DNA methylation status of osteogenic and
New Zealand Dental
14,028
angiogenic genes in gingival tissues of smokers Association Research
and non-smokers
Foundation
2011
Dr Dawn Coates
Bisphosphonate related osteonecrosis of the
jaw (BRONJ) and the role of osteoblasts
2011
Prof Richard Cannon
Assessment of anti fungal compounds for target Otago Innovation Limited
interaction and being efflux pump substrates
* GST exclusive
14,560
New Zealand Lottery
13,467
Grants Board
11,480
Dentistry
31
32
RESEARCH REPORT 2011/2012
Dentistry
Commercial Contracts
Year Approved
Organisation
CBG Health Research Limited
DENTSPLY Australia Pty Ltd
Downie Stewart
Ministry of Health
Southern Implants (Pty) Ltd (South Africa)
University of Canterbury
University of Zurich
Total
377,635
Postgraduate Students
See above for details of postgraduate student numbers.
Awards and Honours
Year Recipient
2012
Dr Masakazu Niimi
2012
Award
Poster prize, 18th Congress, International Society for Human and Animal Mycology, Berlin, Germany
Darnell Kennedy
First Place, Education Sector, Australian Police Journal Awards
(PhD student)
2011
Professor Richard Cannon
Alan Docking Science Award, Australia/New Zealand Division of the International Association for Dental Research
2011
Professor Bernadette
Drummond
Honorary Fellowship, Royal Australasian College of Dental Surgeons
2011
Professor Richard Cannon
Sir John Walsh Research Award, Sir John Walsh Research Institute,
University of Otago
2011
A/P Mary Cullinan
Student Research Mentor Award, Sir John Walsh Research Institute,
University of Otago
2011
Clinical Research Award, Sir John Walsh Research Institute, University of Otago
A/P Warwick Duncan
2011
Dr Ann Holmes
Student Research Support Award, Sir John Walsh Research Institute,
University of Otago
2011
Dr Kate Morgaine
Student Research Mentor Award, Sir John Walsh Research Institute,
University of Otago
2011
Dr Kyoko Niimi
Basic Science Research Award, Sir John Walsh Research Institute,
University of Otago
2011
First prize in the Hatton Poster Awards at the International Association for
Dental Research General Session, San Diego
Grace Lee
(BDS student)
RESEARCH REPORT 2011/2012
FACULTY OF MEDICINE
OTAGO SCHOOL OF MEDICAL SCIENCES
DEPARTMENT OF ANATOMY
Head of Department: Professor Dave Grattan
Email: [email protected]
Website: http://anatomy.otago.ac.nz
Research activity within the Department of Anatomy covers a wide range of topics including: neuroscience, reproductive
biology, developmental biology, clinical and functional anatomy, biological anthropology, and cell biology.
The Department boasts a number of first-rate research facilities including gene sequencers, light microscopy facilities
(including a laser capture micro-dissection system and a Zeiss inverted microscope), X-ray and ultrasound, dedicated image
analysis suites, a plastination laboratory, and an extensive human skeletal remains collection. The Department also houses the
Otago Centres for Electron Microscopy and Confocal Microscopy.
Major Areas of Research Strength
Neuroscience
The Neuroscience Research Group embraces a number of different research strengths in the Department, including
neuroendocrinology, basal ganglia research and research into sexual differentiation.
Neuroendocrine research focuses on the functions of the hormone prolactin, and in particular, the role of prolactin in the
neuroendocrine and neurobiological adaptations of the maternal brain. Specific interests include the control of appetite and
body weight during pregnancy and obesity, plasticity in oxytocin neurons during late pregnancy and lactation, and the role of
prolactin in changes in mood and behaviour in the post partum period.
Dysfunction of the basal ganglia contributes to disorders such as Parkinson’s disease, Huntington’s disease, attention-deficit
hyperactivity disorder (ADHD) and schizophrenia. The Basal Ganglia Research Group is particularly interested in the
functioning of the input and output pathways of the basal ganglia, and how they are involved in learning and movement.
A better understanding of the normal functioning of cells in the basal ganglia will pave the way to better treatments for its
associated disorders.
Men and women are differentially affected by most neurological diseases. Males are more likely to develop ADHD and motor
neuron disease whereas anorexia nervosa is associated more with females. Researchers interested in sexual differentiation have
found that a hormone active in the development of the sex organs in the male embryo, Mullerian inhibiting substance (MIS),
is also present in the brain, creating a sex difference there too. MIS produces subtle differences in both the size and number
of motor neurons between the two sexes, potentially explaining why men are more susceptible to motor neuron disease than
females. Ongoing research will investigate how MIS also regulates other parts of the brain. It is hoped that this research could,
in time, contribute to more effective treatments for some neurological disorders.
Clinical and functional anatomy
Particular emphasis is placed on anatomical research that is relevant to surgical/orthopaedic and physiotherapy practice, as
well as biomaterials and tissue engineering. Current areas of research include: the clinical anatomy of vascular structures
including intracranial venous drainage; deep fasciae; the musculoskeletal system; and the head and neck region including
forensic facial approximation; iatrogenic nerve injury; dysphagia; and development and biological characterisation of
biomaterials. A variety of techniques are utilised including: gross dissection, microdissection, epoxy sheet plastination,
corrosion casting, imaging techniques such as ultrasound and magnetic resonance, protein analytical techniques, cell culture,
in vivo (small and large animal surgery), histology, microCT, and immunohistochemistry. Some of this expertise is utilised to
provide R&D services to NZ wool, food/ingredient, and biotechnology industries.
Reproduction, development and genomics
Research in this area focuses on both human and animal reproduction, often with strong ties with the neuroendocrinologists of
the Neuroscience Research Group. Current major themes include: work on sperm function and male fertility; poly-cystic ovarian
syndrome; prostate diseases, particularly prostate cancer. This group also has an active programme in animal development
and genomics, often with a strong comparative element. Current major projects in these areas include: investigations into
the evolution of developmental pathways in vertebrates; work on mammalian development, particularly early embryonic
development and sexual development; and sex determination in fishes. Much of the latter research is powered by the latest
developments in genomic sciences, including a variety of next generation technologies such as RNA-seq and Chip seq.
Biological anthropology
A particular area of research interest is the biological anthropology of prehistoric populations in Southeast Asia and the
Pacific. This research uses skeletal remains from archaeological excavations as the primary source of data. An additional
research focus is using ancient and modern DNA techniques to address questions of human migrations and interactions. This
includes identifying the origins of Pacific peoples and their commensal plants and animals in order to better understand the
settlement, history and prehistory of the Pacific and New Zealand.
OSMS
33
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34
RESEARCH REPORT 2011/2012
Other research
The Department of Anatomy is a research-intensive department and has a number of other research strengths including:
alcohol and brain development; medical education; molecular embryology; development of bone graft substitutes and
composite surgical appliances; and molecular mechanisms of learning and memory.
External Grants > $40,000 Awarded 2011-2012
Year
PI
Project Title
2011
Prof David Grattan
Signalling pathways involved in the control of glucose metabolism
Funder
$*
2012
Prof Dave Grattan
Mechanism of hormone entry across the
blood-brain-barrier
Royal Society of 847,826
New Zealand – Marsden
2012
A/P Greg Anderson
Overcoming anxiety: the neuroendocrine strategy of new mothers
Royal Society of
847,826
New Zealand – Marsden
2012
Dr Nancy Beavan
“Living in the shadow of Angkor”: Responses Royal Society of
626,087
and strategies of upland social groups to polity New Zealand – Marsden
demise in the late-to post-Angkor period
Health Research Council
1,786,895
of New Zealand
(subcontract)
2012
Dr Patrice Rosengrave How do males adjust their sperm quality in
response to social cues?
Royal Society of New Zealand – Marsden
Fast Start
300,000
2011
Dr Sheri Johnson
Are old males still good males and can
females tell the difference?
Royal Society of
300,000
New Zealand – Marsden
Fast Start
2011
Dr Ann Horsburgh Inventing cattle: A genetic study of cattle
domestication through next generation
sequencing
Royal Society of 299,983
New Zealand – Marsden
Fast Start
2011
Dr Christine Jasoni
NRCGD: Interventions in developmental
TEC (subcontract)
278,873
programming
2011
Dr Kathie Overeem
An examination of microRNA expression
Neurological Foundation
190,352
abnormalities as a result of maternal immune of New Zealand
activation: A search for epigenetic abnormalities
associated with increased risk for schizophrenia
development
2011
Dr Elspeth Gold
Does activin C modulate reproductive tumor
development in inhibin mice? Monash University
153,814
(subcontract)
2011
Prof Lisa Matisoo-Smith Allan Wilson Centre – Variation – Linking the TEC (subcontract)
140,244
past and present – ancient DNA
2012
Dr Joanna Williams
MicroRNA regulated in dentate gyrus granule
cells following LTP induction in vivo
Neurological Foundation
107,754
of New Zealand
2012
Prof Neil Gemmell
Allan Wilson Centre: The Tuatara genome
TEC (subcontract)
105,000
project strategic initiative
2012
Prof Neil Gemmell
Allan Wilson Centre – PhD Scholarship Feral
Pigs – a Replicated Experiment in Evolution
Massey University
105,000
2012
Dr Christine Jasoni
NRCGD: Uncovering molecular changes in the fetal brain that can explain how maternal
obesity elevates offspring obesity risk
NRCGD (subcontract)
104,279
2012
Prof Neil Gemmell
Allan Wilson Centre: The Tuatara Genome
TEC (subcontract)
Project Strategic Initiative
102,000
RESEARCH REPORT 2011/2012
2012
A/P John Reynolds
Modulating interhemispheric inhibition to
improve functional recovery after stroke
Neurological Foundation
84,000
of New Zealand
2011
Dr Kathie Overeem
An examination of circulating microRNA as
biomarkers for schizophrenia
New Zealand Lottery
83,000
Grants Board
2012
Prof Neil Gemmell
Allan Wilson Centre: Theme 1 Genomics and TEC (subcontract) 59,960
Biomathematics; Theme 2 Biodiversity and
Human Impacts 2013
2011
Prof Neil Gemmell
Allan Wilson Centre: Genomics and
TEC (subcontract)
biomathematics 2012
58,710
2012
Prof Lisa Matisoo-Smith Allan Wilson Centre: Theme 3 Human impact TEC (subcontract)
and wellbeing in NZ and the Pacific 2013
57,894
2011
Prof Lisa Matisoo-Smith Allan Wilson Centre: Genomic and
TEC (subcontract)
biomathematics 2012
57,102
2011
Dr Christine Jasoni
Maternal obesity alters fetal brain circuitry
development
New Zealand Lottery
49,500
Grants Board
2012
A/P Greg Anderson
Neuroendocrine mechanisms linking insulin
and infertility
HS and JC Anderson
Charitable Trust
43,478
* GST exclusive
Commercial Contracts
Year Approved
2011-12 Total
Organisation
Agricultural and Marketing Research and Development Trust
Department of Conservation
F Hoffman-La Roche Ltd
Industrial Research Ltd
Physiotherapy New Zealand
Vitaco Health (NZ) Limited
University of Canterbury
618,807
Postgraduate Students
Total Head Count
PhD
2011
Masters†
2012
5268
2929
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Professor Lisa Matisoo-Smith
James Cook Research Fellowship, Royal Society of New Zealand
2012
Dr Michael Knapp
Early Career Award for Distinction in Research, University of Otago
2012
Dr Siân Halcrow
Early Career Award for Distinction in Research, University of Otago
2012
Dr Andrew Clarkson
Early Career Award for Distinction in Research, University of Otago
2012
Professor Mark Stringer
American Academy of Pediatrics Award, Stephen L Gans Distinguished Overseas Lectureship, New Orleans, USA
OSMS
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RESEARCH REPORT 2011/2012
OSMS
2012
Professor Mark Stringer
Best Teacher: OUSA Teaching Excellence Award
2012
Dr Elspeth Gold
Excellence in Postgraduate Supervision, Otago School of Medical Sciences Annual Awards
2012
Ms Carol Dunstone
Distinguished Research Support Award, Otago School of Medical Sciences Annual Awards
2012
Professor Jean Fleming
Life Membership, New Zealand International Science Festival
2012
Dr Michael Knapp
Emerging Research Award, Queenstown Molecular Biology conference
2012
Dr Megan Wilson
Life Technologies Award, Queenstown Molecular Biology conference
2012
Darnelle Kennedy
First Place Education Sector, Australian Police Journal Awards
(PhD student)
2012
Laura Boddington
Miller Scholarship, Neurological Foundation of New Zealand
2012
Ali Mirjalili
(PhD student)
Prize for best oral presentation, Annual Meeting of New Zealand
Association of General Surgeons
Ali Mirjalili
Prize for best oral presentation, Head and Neck Surgery Conference,
2012
(PhD student)Wellington
2012
(PhD student)
First prize, student podium presentation, Australasian Society for Human
Biology 26th Annual Conference Vanuatu
2012
Christina Stantis
(PhD student)
Best student podium prize, Otago International Health Research network
Annual Conference
2012
Tessa Sanders
Best PhD student speaker prize, Gravida Annual Science symposium
(PhD student)
2012
Stephanie Shkrum
Joon Kim
(PGDipSci)
2012
Joon Kim
(PGDipSci)
2012
Papillon Gustafson BSc(Hons)
Early Career Student Prize, Reproduction and Development Research Symposium
Best Student Presentation Award, New Zealand Society for Endocrinology
First Prize, OMSRS pre-doctoral presentations
2011
Professor Dave Grattan
Distinguished Researcher of the Year, Otago School of Medical Sciences
Annual Awards
2011
Companion of the Royal Society of New Zealand
Professor Jean Fleming
2011
Professor Mark Stringer
Distinguished Academic Teacher, Otago School of Medical Sciences
Annual Awards
2011
Best Teacher, OUSA Teaching Excellence Award
Professor Mark Stringer
2011
A/P Greg Anderson
Health Science Postgraduate Supervisor of the Year, University of Otago and OUSA Supervisor of the Year Awards
2011
Exceptional PhD Thesis, University of Otago
Dr Amy Osborne
2011
Joanne Gillum
2011
2011
Research Support Staff Award, Otago School of Medical Sciences
Annual Awards
Jason Woon
Best Student Presentation, 8th Annual ANZACA Conference
(PhD student)
Ali Mirjalili
First Place Poster Prize, New Zealand Association of Surgeons General
(PhD student)Meeting
RESEARCH REPORT 2011/2012
DEPARTMENT OF BIOCHEMISTRY
Head of Department: Professor Kurt Krause
Email: [email protected]
Website: http://biochem.otago.ac.nz
Research in the Department is largely concerned with fundamental processes associated with a number of significant
biomedical and biological problems: heart disease; cancer; diabetes, rheumatoid arthritis and gout; memory and neurological
disease; pathogenic viruses, micro-organisms and fungi; flowering, senescence, photosynthesis, nitrogen utilisation in plants
and symbiosis; genomics, genetics and embryo development; cold adaptation; eukaryotic retroelements; developmental
biology; body weight and cell signalling; molecular evolution; apoptosis; and biodiversity. Extensive use is made of
bioinformatics, next-generation sequencing, microarray technology structural biology and proteomics tools. The Otago
Genomics Facility, the Centre for Protein Research and the X-ray facility for protein structure determination are all located
within the Department. Departmental staff are involved in New Zealand Genomics Ltd, a new entity supplying national
infrastructure for fast through-put sequencing.
Major Areas of Research Strength
Cancer genetics
The Centre for Translational Cancer Research is the hub for cancer genetics research within the department. Staff undertake
research with an emphasis on studies that can be expected to improve cancer treatment in a relatively short timeframe.
Projects range from drug development to immunotherapy and include diagnostic test design and personalised medicine.
The latter includes the development of simple tests that can be used to select the best chemotherapy treatment for individual
patients and other tests that predict an individual’s prognosis and the risk of treatment side-effects.
Website: www.ctcr.otago.ac.nz
Functional genomics, gene expression and proteomics
The era of automated DNA sequencing and genome databases (genomics) has arrived and with it have come new methods
for identifying particular genes and their protein products (proteomics). It is the expression of a set of genes in a particular
cell type which defines the function of that cell. The pattern of gene expression can change, for example during development,
or as a result of mutation or disease, so that analysis of altered expression profiles provides fundamental information on basic
biological processes. Understanding how such changes come about requires knowledge of factors that control gene expression
as well as the functions of the individual protein products. Assigning function to an unknown protein depends on knowing its
precise composition and 3-dimensional structure, as well as its interaction partner. Functional proteomics leads in turn to a
deeper understanding of physiological processes.
Infectious disease
There is a worldwide resurgence in infectious diseases which pose a threat to our population and to our native and domestic
animals. Researchers are seeking to develop diagnostics, antimicrobials and vaccines to address important problems caused
by such diseases. The molecular structures of proteins inside infectious viruses and microbes are being probed to seek out
weaknesses that can be exploited. New drugs to combat these diseases can then be designed. Specific disease targets are
tuberculosis, HIV/AIDS, streptococcal disease, poxviruses, Candida and MRSA. Research in this area has been bolstered by the
establishment of a high-flux protein crystallography laboratory in the Department. Many staff are members of the Webster
Centre for Infectious Diseases.
Autoimmune disease
Research focuses on the underlying genetics of gout and rheumatoid arthritis, two common forms of autoimmune diseases.
Large databases of DNA obtained from sufferers of autoimmune diseases are being used to identify causative genes.
Researchers have confirmed that the gene PTPN22 is one of the factors that causes rheumatoid arthritis, only the second gene
in the past 25 years to be universally accepted as a causative factor. The group has also developed microarray technology which
has allowed a genome-wide scan to simultaneously test all genes for association with rheumatoid arthritis. This technology
is being applied to other chronic conditions in order to uncover their pathogenesis, including abdominal aortic aneurysm,
schizophrenia, gout and inflammatory bowel disease.
Other research
The Department of Biochemistry is a research-intensive department and has a number of other areas of research strength
including: bioinformatics, bacterial molecular biology; evolution and development; plant biochemistry; proteomics; and heart
disease. Many of these project areas are funded by the HRC, MBIE or Marsden grants.
OSMS
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RESEARCH REPORT 2011/2012
OSMS
External Grants > $40,000 Awarded 2011-2012
Year
PI
Project Title
Funder
2011
A/P Tony Merriman
Application of genetics to the pathogenesis
of common chronic conditions
Health Research 4,765,885
Council of NZ
2011
A/P Peter Dearden NRCGD: Mechanisms and consequences of TEC (subcontract)
developmental plasticity
1,095,112
2011
Prof Parry Guilford
Synthetic lethal targeting of the tumour
suppressor gene CDH1 in common cancers
1,080,000
2012
Dr Wayne Patrick
New Insights into old problems: Evolution of Royal Society of
1,000,000
protein folds, protein functions and streamlined New Zealand – Marsden
genomes
Health Research Council of NZ
$*
2012
Prof Parry Guilford
Designer diagnostics
Ministry of Business, 910,558
Innovation and Employment
2011
Prof Catherine Day
E2s and the regulation of ubiquitin transfer
Royal Society of 856,521
New Zealand – Marsden
2011
Prof Parry Guilford
Health Research
820,302
Council of NZ
Single cell RNA profiling for the early
detection of urological cancers
2012
Dr Richard Macknight Molecular understanding of flowering time
regulation in legumes
Royal Society of
791,304
New Zealand – Marsden
2012
Dr Lynette Brownfield The role of asymmetric division in male
germ-line specification in flowering plants
Royal Society of
New Zealand – Marsden
300,000
2012
Dr Anita Dunbier
Hormonal regulation of immune cells: Does Royal Society of
anti-hormone therapy inadvertently fuel cancer? New Zealand – Marsden
Fast Start
300,000
2011
Dr Elizabeth Duncan Plastic genomes: does genome structure
facilitate phenotypic plasticity?
2011
Dr Anne von
Zychlinski-Kleffmann
Royal Society of 300,000
New Zealand – Marsden
Fast Start
New biomarkers and molecular signatures
National Heart Foundation 180,000
to estimate an Lp(a)-related CVD-risk by
of NZ
comparing and quantifying the Lp(a)-proteome
from CVD and healthy subjects.
2011
A/P Sally McCormick Connections between Lp(a) and HDL
National Heart Foundation 157,968
of NZ
2011
Prof Parry Guilford
Genetic predictors of capecitabine toxicity
Cancer Society of 144,818
New Zealand Inc
2012
Dr Chris Brown PomBase – a model organism database for
the major model organism fission yeast
Wellcome Trust
134,489
(subcontract)
2011
A/P Russell Poulter
Activation of latent HIV by cyclic analogues
of Tat
Bill & Melinda Gates
123,487
Foundation
2011
A/P Russell Poulter
Targeting HIV provirus with novel restriction
endonucleases
Bill & Melinda Gates
121,949
Foundation
2011
Dr Stephanie Hughes
Lysosomal function in childhood
neurodegenerative disease
Neurological Foundation
103,143
of New Zealand
2011
Prof Iain Lamont
Antibiotic resistance mechanisms of
Cure Kids
103,035
Pseudomonas aeruginosa in cystic fibrosis
RESEARCH REPORT 2011/2012
2012
Prof Kurt Krause
Broad-spectrum antimicrobials targeting the
NIH
D-alanine pathway
102,347
2012
Dr Stephanie Hughes
Optimising gene therapy strategies in Batten
Cure Kids
disease
99,935
2011
Prof Kurt Krause
Broad-spectrum antimicrobials targeting the
NIH
99,851
D-alanine pathway
2012
Dr Wayne Patrick
Proteins from pieces: subdomain assembly in
the evolution of protein structure
Royal Society of
87,428
New Zealand
2012
Dr Liz Ledgerwood
Are cell death pathways important in platelet
formation in humans?
New Zealand Lottery
79,000
Grants Board
2012
Dr Mik Black
Analysis of genomic data in human tumours and mouse models of cancer
The Methodist Hospital
77,366
Research Institute
2012
Prof Iain Lamont
Molecular analysis of Pseudomonas infections HS and JC Anderson in patients with cystic fybrosis and
Charitable Trust
bronchiectasis
2011
A/P Peter Dearden
NRCGD: Understanding fetal programming
TEC (subcontract)
64,883
in sheep
73,523
2012
Dr Sigurd Wilbanks
Biosynthesis of potent analgesics
New Zealand Lottery
62,015
Grants Board
2011
Prof Parry Guilford
Gastric cancer: Where from? Where to?
Health Research Council 49,000
of NZ (subcontract)
2012
Dr Mik Black
Analysis of genomic data in human tumours and mouse models of cancer
The Methodist Hospital
44,530
Research Institute
2011
Prof Parry Guilford
Genetic predictors of capecitabine toxicity
Grants Board
New Zealand Lottery
41,000
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
AgResearch
Alere San Diego Inc
Canterbury District Health Board
Ministry of Agriculture and Forestry
Ministry of Business, Innovation and Employment
Ministry for Primary Industries
New Zealand Forest Research Institute Ltd
New Zealand Genomics Limited
Plant and Food Research
Seeka Kiwifruit Industries Limited
Victoria University, Wellington
University of Auckland
2,079,616
OSMS
39
40
RESEARCH REPORT 2011/2012
OSMS
Postgraduate Students
Total Head Count
PhD
2011
2012
3843
1826
Masters†
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Peter Mace
Rutherford Discovery Fellowship, Royal Society of New Zealand
2012
Nicole Neverman
Miller PhD Scholarship, Neurological Foundation of New Zealand
(PhD student)
2012
(MSc student)
2012
Dr Gemma Dickson
Exceptional PhD Thesis, University of Otago
2012
Dr Simon Jackson
Exceptional PhD Thesis, University of Otago
2012
Dr Brie Sorrenson
Exceptional PhD Thesis, University of Otago
2011
Professor Warren Tate
Companion of the New Zealand Order of Merit for services to science
2011
Dr Anita Dunbier
Sir Charles Hercus Fellowship, Health Research Council of New Zealand
2011
Professor Catherine Day
Distinguished Researcher of the Year Award, Otago School of Medical Sciences
2011
Dr Wayne Patrick
Rutherford Discovery Fellowship, Royal Society of New Zealand
Jared Fudge
Best Student Poster Prize, New Zealand Society of Plant Biologists conference
2011
Professor Warren Tate
Excellence in Postgraduate Supervision Award, Otago School of
Medical Sciences
2011
Tony Zaharic
Sustained Excellence in Tertiary Teaching Award, Tertiary Teaching Excellence Awards, Ako Aotearoa
2011
Tony Zaharic
University of Otago Teaching Excellence Award
2011
Sharleen Rae
(PhD student)
First Prize Student Poster Competition, Health Sciences Research Forum
2012
Nicole Neverman
(PhD student)
Student Poster Award, 13th International Conference on Neuronal Ceroid
Lipofuscinsoses, London
RESEARCH REPORT 2011/2012
DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY
Head of Department: Professor Vernon Ward
Email: [email protected]
Website: http://micro.otago.ac.nz
The main research interests of staff in the Department of Microbiology and Immunology lie in the areas of agricultural
microbiology, biotechnology, clinical microbiology and infectious diseases, food-borne pathogens, microbial genetics,
immunology, bacteriophage molecular biology, innate immunity and vaccine technology. Research is carried out in the
following key areas: antibiotic resistance in bacteria, clostridial genetics, dendritic cells and their function, environmental
microbiology and bioremediation, insect viruses and the biological control of insect pests, intestinal microflora, milk products,
mycobacterial diseases of animals, microbial genomics, nitrogen fixing bacteria and improving plant growth, streptococci and
the biological control of streptococcal diseases, vaccine development and delivery systems, viruses and viral vaccines.
Major Areas of Research Strength
Viral technologies
A principal goal of virus research is to characterise virus to host interactions. Many viruses are a threat because they express a
plethora of factors that subvert, suppress and generally manipulate human defences against infection. Viral factors that have
been discovered and characterised include a set of chemokine binding proteins, a cytokine, a new class of vascular endothelial
growth factor, a potent apoptosis inhibitor, a cell cycle regulator and a family of proteins that exploit the cell’s ubiquitination
machinery. These viral factors target critical elements of our defences, and their analysis gives important new insights into
both viral pathogenesis and our own physiological processes. There is also the opportunity to exploit these novel viral factors
as new therapeutics in the treatment of pathologies quite removed from virus infection, for example, non-healing wounds and
inflammatory disorders.
Immunology
An understanding of the immune response underpins studies of infectious and autoimmune diseases. Cures for these diseases,
as well as cancer and asthma, require knowledge of the immune response and how it can be manipulated. Research focuses
on the development of vaccines against cancer and infectious diseases such as Chlamydia, Johne’s Disease and tuberculosis.
A major theme is the study of the cells and the molecules involved in antigen presentation during immune responses to
allogeneic transplants. Research also seeks to understand the immunology of autoimmune inflammatory diseases and the role
of the immune system in asthma and other allergies.
Disease in animals
Research in the Disease Research Laboratory (DRL) targets immunity to mycobacterial infections in domestic livestock (sheep
and deer) and wildlife (Cape buffalo). All facets of immunity to infection including improved diagnosis, vaccination and
selection for heritable resistance are studied. Diagnostic tests developed by the Laboratory are used extensively for immune
profiling of Mycobacterial diseases in ruminants. The main diseases being studied are Tuberculosis (TB) which is caused by
Mycobacterium bovis and Johne’s disease (JD) which is caused by Mycobacterium paratuberculosis.
Gastrointestinal microbiology
Complex communities of bacteria inhabit the bowels of animals and have important influences on health and disease.
These communities are referred to as the gut microbiota. Research projects include the microbiology of inflammatory
bowel diseases, the use of a unique colony of Lactobacillus-free mice in investigating the molecular foundations of gut
autochthony using lactobacilli as model bacteria, engineering bowel communities by dietary manipulation, and the impact of
bifidobacterial species on the activation of human dendritic cells with respect to atopic diseases.
Bacterial physiology
Research in this area focuses on how bacteria function under different environments. The membrane proteins and
signaling pathways involved in this adaptation and how they control the physiological response of a particular bacterium
to environmental signals is a major theme. These studies utilise modern technologies (e.g. proteomics, transcriptomics,
molecular biology and structural biology) to address important questions in bacterial adaptation to the environment.
OSMS
41
42
RESEARCH REPORT 2011/2012
OSMS
External Grants > $40,000 Awarded 2011-2012
Year
PI
2011
Dr Peter Fineran
Project Title
Funder
How do bacterial “adaptive immune systems”
protect microbial cells against viral infection?
Royal Society of
800,000
New Zealand
2011
Prof Greg Cook
Molecular approaches to TB persistence and
pathogenesis
Health Research Council
662,441
of NZ (subcontract)
2011
Prof Greg Cook
Interactive metabolomics of macrophages and National Institutes
625,639
Mycobacterium tuberculosis
of Health (subcontract)
2011
Prof Greg Cook
Molecular approaches to TB persistence
and pathogenesis
Health Research Council
562,479
of NZ (subcontract)
2011
Carbohydrate recognition and signalling
University of Aarhus
Prof Clive Ronson
$*
442,813
2012
Dr Zabeen Lateef Multifunctional roles of a norovirus protein
Health Research
362,495
Council of NZ 2012
Prof Greg Cook
Structure and function of membrane-bound
protein complexes Royal Society of
220,000
New Zealand
2012
Dr Matloob Husain
The role of multi-substrate deacetylase
HDAC6 in influenza A virus replication
Health Research
150,000
Council of NZ 2012
A/P Alex McLellan Development of a drug delivery system for
Mycobacterium tuberculosis
New Zealand Lottery
95,000
Grants Board
2012
Dr Joanna Kirman
Do central memory-like CD4+ cells protect
against tuberculosis?
New Zealand Lottery
93,713
Grants Board
2011
Prof Gerald Tannock Inflammatory Bowel Disease: An EU-NZ
Royal Society of
57,682
integrated approach for characterizing its
New Zealand
molecular multifactorial mechanisms 2011
Dr Ros Kemp Manipulating the normal gut immune response Genesis Oncology Trust
54,807
to cure colorectal cancer
2012
Dr Ros Kemp
Do we need gut-specific T cells to kill
gut-specific tumours?
New Zealand Lottery
50,000
Grants Board
2012
Dr Matloob Husain
Histone deacetylases: A family of human
proteins that regulate influenza virus pathogenesis
HS and JC Anderson
Charitable Trust
43,478
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
AgResearch
Fonterra Co-operative Group Limited
Industrial Research Ltd
Leo Industries Limited
Ministry of Agriculture and Forestry
New Zealand Institute of Crop and Food Research Ltd
Plant and Food Research
Schering Plough Animal Health Ltd
Seperex Nutritional Limited
Synlait Milk Limited
Trinity Bioactives Limited
Zespri International Ltd
2,579,127
RESEARCH REPORT 2011/2012
Postgraduate Students
Total Head Count
PhD
2011
2012
3339
1512
Masters†
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Professor Frank Griffin
Fellow, Royal Society of New Zealand
2012
Professor Greg Cook
Distinguished Speaker Award, 57th Annual Scientific Meeting, New Zealand Microbiological Society
2012
Dr Heather Brooks
Best Lecturer Award, OUMSA Teaching Excellence Awards 2012
Andrew Highton
Otago Medical Society Poster Prize
(PhD student)
2012
Dr Matthew McNeil
2012
Brooke Dobson
Professor Sandy Smith Memorial Scholarship
(PhD student)
2012
(PhD student)
2012
(PhD student)
Corinna Richter
Andrew Highton
Exceptional PhD Thesis, University of Otago
Professor Sandy Smith Memorial Scholarship
Professor Sandy Smith Memorial Scholarship
2012
Michelle Wilson
Marbrook Research Technician Award, New Zealand Branch Meeting of the Australasian Society of Immunology
2012
Pecha Kucha Presentation Award, New Zealand Branch Meeting of the
Australasian Society of Immunology
Farah Al-Barwani
(PhD student)
2012
Cameron Field
Buck Student Presentation Award, New Zealand Branch Meeting of the Australasian Society of Immunology
2011
Professor Gerald Tannock
Fellow, Royal Society of New Zealand
2011
Professor Greg Cook
James Cook Fellowship, Royal Society of New Zealand
2011
Dr Peter Fineran
Rutherford Discovery Fellowship, Royal Society of New Zealand
2011
Dr Peter Fineran
Early Career Award for Distinction in Research, University of Otago
2011
Dr Julie Weaver
Distinguished Teaching Fellow, Otago School of Medical Sciences
Annual Awards
2011
Best Lecturer Award, OUMSA Teaching Excellence Awards
Dr Heather Brooks
2011
Chris Rodgers
Distinguished Research Support Staff Award, Otago School of Medical Sciences Annual Awards
2011
Charlotte Wilson
Professor Sandy Smith Memorial Scholarship
(PhD student)
2011
(PhD student)
2011
Clare Burn
2011
Estelle Baker
Best Research Presentation, Otago School of Medical Sciences PhD (PhD student)Colloquium
2011
Corinna Richter
(PhD student)
Ron Dy
Professor Sandy Smith Memorial Scholarship
Student Speaker Award, Otago Medical School Research Society
Poster Prize, Biointeractions Satellite Meeting
OSMS
43
44
RESEARCH REPORT 2011/2012
OSMS
DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY
Head of Department: Associate Professor Rhonda Rosengren
Email: [email protected]
Website: http://phal.otago.ac.nz
The Department of Pharmacology and Toxicology engages in high quality, internationally-recognised research focused on
the following themes: cellular and molecular neuropharmacology, neurodegeneration, neuroprotection and neurotoxicology;
cardiovascular signalling and cardioprotection; cancer drug development, drug metabolism, drug treatment of chronic
pain, and vestibular pharmacology. State-of-the-art technologies, including in vivo disease models, are used to undertake
integrative, cellular and molecular investigations aimed at understanding animal and human pathophysiology, and to
delineate targets for novel drugs.
Major Areas of Research Strength
Vestibular and auditory research
Members of the Vestibular and Auditory Research Group are interested in the functional deficits observed in the CNS
following damage to the inner ear. These deficits include balance disorders, loss of gaze holding ability, disruption of hearing
including tinnitus, and of surprise to many people, cognitive dysfunction. Questions relating to these disorders are pursued in
a human testing facility within the Department.
Cancer drug development
Research focuses on the development of novel treatments for cancer. This includes using medicinal chemistry to design novel
glutathione peroxide mimics and nitric oxide donors, which can be used to treat a variety of cancers. Synthetic chemistry is
also used to design novel drugs to specifically target triple negative breast cancer, a highly aggressive form of breast cancer.
Nanotechnology and tumor homing peptides are then used to specifically deliver the drug to the tumor.
Drug treatment of chronic pain
Chronic pain is often caused by damage to the central nervous system, and can be very difficult to treat. Recent research
has shown that this ‘neuropathic pain’ can be caused by inflammation within the central nervous system. The Department
investigates the mechanisms underlying this process and how to alter them with new drugs, aiming to develop new and
improved treatments for chronic pain.
Cardio-renal protection
This research area encompasses three main themes. The first is pre-transplant renal graft conditioning, which examines the
reno-vascular protective value of novel gaseous agents as transplant perfusion adjuncts. The second is renal denervation,
which is a fast developing clinical field into which the department has provided strong scientific evidence into the therapeutic
mechanism of action in renal disease. Lastly, the department also investigates cardioprotection in status epilepticus, which
determines the effectiveness of pharmacological intervention during prolonged seizure.
External Grants > $40,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2012
Dr Ivan Sammut New adjuncts for transplant solutions
Ministry of Business, 827,368
Innovation and Employment
2011
Dr Sebastien Taurin
Effect of raloxifene on estrogen receptor
negative breast cancer tumour growth
Health Research 145,000
Council of NZ
2012
Prof Paul Smith
Novel GABAB receptor agonists for the
treatment of chronic tinnitus
Neurological Foundation
132,306
of New Zealand
2011
Dr Yiwen Zheng
Therapeutic window of L-baclofen for noise- Neurological Foundation
123,203
induced chronic tinnitus in rats and GABAB
of New Zealand
receptor-mediated mechanisms
2011
Prof Paul Smith
Role of inflammation in tinnitus and the
New Zealand Guardian
70,000
therapeutic potential of a selective COX-1
Trust Company Ltd
inhibitor in tinnitus treatment
2012
Prof Paul Smith
Vestibular system, cognition and vegetative
regulations
2011
Dr John Ashton
Microscope - TB-Nikon-1104c
* GST exclusive
Royal Society of 65,683
New Zealand
New Zealand Lottery
Grants Board
59,000
RESEARCH REPORT 2011/2012
Commercial Contracts
Year Approved
Organisation
2011-12
Lincoln University
Total
177,776
Postgraduate Students
Total Head Count
2011
2012
PhD
1310
Masters†
44
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2012
A/P Steve Kerr
Top Postgraduate Supervisor, OUSA University of Otago Supervisor of the Year Awards
2012
Simran Magoo
Winner of the Fred Fastier Oral Prize, ASCEPT NZ 2011
Jack Rivers
Peoples’ Choice Award, Australasian Three Minute Thesis Competition
(PhD student)
2011
(PhD student)
2011
Dr Ian Winburn
Exceptional PhD Thesis, University of Otago
2011
Babasheb Yadav
(PhD student)
Student Poster Prize, Queenstown Molecular Biology Meeting
2011
Yimin Yao
Bullivant Oral Prize, Physiological Society of New Zealand
(PhD student)
Jack Rivers
Winner, Three Minute Thesis Competition, University of Otago
OSMS
45
46
RESEARCH REPORT 2011/2012
OSMS
DEPARTMENT OF PHYSIOLOGY
Head of Department: Professor Brian Hyland
Email: [email protected]
Website: http://phsl.otago.ac.nz
The Department of Physiology is engaged in high quality, internationally recognised physiological research focused on the
three major themes of cardiovascular and respiratory physiology, cellular and molecular neuroscience, and membrane and ion
transport.
Members of the Department use state-of-the-art technologies, including transgenic mouse models, synchrotron radiation, and
single molecule detection in living cells, to undertake integrative, cellular and molecular investigations aimed at understanding
animal and human physiology.
Major Areas of Research Strength
Neuroendocrine control of reproduction
Fertility is declining in western societies, including New Zealand. Major research being undertaken in the Department through
the Centre for Neuroendocrinology is focused on understanding the ways in which the brain controls reproduction, including
the onset of puberty, ovulation, birth and lactation. Recent research has shown that a newly-discovered protein that is essential
for puberty, kisspeptin, also plays a critical role in the control of ovulation by mediating estrogen’s actions in the adult brain
– a finding that may offer hope to the infertile. On-going work aims to determine how dysfunction of the brain circuits that
regulate fertility might lead to polycystic ovarian syndrome, the leading cause of infertility in women. Other current research
focuses on whether kisspeptin and another protein, prolactin, might be involved in preterm labour.
Website: www.neuroendocrinology.otago.ac.nz
Neurological disorders and the control of movement
Neurological disorders are an increasing health problem, particularly in an aging population. Unfortunately, many of these
disorders, including those that impair movement and restrict mobility, are common, often poorly treated and get progressively
worse over time. As a result they create a significant health burden for patients and carers alike. Research in the Department
aims to address these problems by exploring the brain circuits and signals that initiate and refine movement and how these
signals are transmitted via the spinal cord and muscles to engage movement. Recent research has identified how even a
mild miss-timing of the signals from a brain region called the cerebellum causes significant loss of fine movement control.
The ultimate aim is to identify therapeutic targets, approaches and devices for the early and better treatment of Parkinson’s
disease, ataxia (lack of coordination), sarcopenia (age-related muscle weakness), spinal injury, multiple sclerosis, epilepsy and
Alzheimer’s disease.
Membrane and ion transport
This theme centres around investigations into the mechanisms and regulation of solute and water movement across cell
membranes and resultant pathologies. Current areas of interest include the regulation of epithelial ion channels and
transporters by binding proteins, solutes and pharmacological agents; epithelial fluid and electrolyte transport in the intestine
and the interaction of bacteria with the intestine; the role of calcium transport proteins in intracellular calcium signalling; and
the control of sodium, potassium, urate and water handling by the kidney. Cardiovascular and respiratory physiology
Research is conducted into cardiovascular and respiratory control and disease processes such as atherosclerosis, heart failure,
obesity, pulmonary hypertension, renal failure, rheumatoid arthritis and systemic hypertension. Specific areas of interest
include: neural control of the heart and vasculature of the lungs, kidneys and skeletal muscle; inflammation; exercise and
fatigue. Recent investigations have demonstrated that control of the cardiovascular system by the nervous system adversely
changes in heart failure and pulmonary hypertension; and that the hormone gherlin has protective effects after a heart attack.
External Grants > $40,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2012
Prof Allan Herbison
Neural control of fertility
Health Research
Council of NZ
4,844,983
2012
Prof Brian Hyland
Health Research Council of NZ
1,166,489 2011
Prof Allan Herbison
Understanding kisspeptin neurons
Health Research Council of NZ
1,002,385
2012
Prof Allan Herbison
Royal Society of
847,826
New Zealand – Marsden
Restoring thalamocortical activity to treat Parkinson’s disease symptoms
Recording the electrical activity of GnRH neurons in vivo
RESEARCH REPORT 2011/2012
2011
Dr Istvan Abraham
ANGELS as a potential treatment for
Alzheimer’s disease
Health Research
782,886
Council of NZ
2011
Dr Rebecca Campbell Understanding the neuroendocrine
abnormalities of polycystic ovarian syndrome
Health Research
650,736
Council of NZ 2011
A/P Fiona McDonald The structure and function of COMMD
protein complexes Royal Society of 240,257
New Zealand
(subcontract)
2011
Dr Istvan Abraham
Live cell single molecule imaging of
Neurological Foundation
205,721
estrogen-induced neuroprotective mechanisms of New Zealand
on cholinergic neurons
2011
Prof Brian Hyland
Effect of ghrelin on activity of neurons in the
Neurological Foundation
168,219
brain reward system and on their response to of New Zealand
food-reward predicting cues in normal and
Parkinson’s disease model rats
2011
Dr Ruth Empson
Health Research Microscope
2011
Dr Andrew Bahn
New Zealand Lottery
150,000
Grants Board
Identification of drug uptake transporters and Prostate Cancer Foundation 104,559
their regulation in prostate cancer cells via
of New Zealand
miRNAs
2011
Dr Sam Lucas
Brain blood flow and sleep apnoea
New Zealand Lottery
Grants Board
56,348
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters †
2011
2012
2421
29
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Jenny Clarkson
First Prize, Otago Medical School Research Society Staff Speaker Awards
2012
Manesh Deo
Heart Theme Student Poster Prize, MedSci Congress, Queenstown
2012
Su Han
(BMedSc Hons student)
Otago Medical School Research Society PhD Oral Presentation Prize
(PhD student)
2012
(PhD student)Research
Malinda Tantirigama
2012
Aye Thaung
Mary Bullivant Prize, Physiological Society of New Zealand
2012
Mahsa Moaddab
(PhD student)
Journal of Neuroendocrinology Student Poster Presentation Prize, Medical
Sciences Congress
2012
A/P Grant Butt
Distinguished Academic Teacher, Otago School of Medical Sciences Awards
2012
Dianne Galvin
Goddard Student Poster Prize, Australasian Winter Conference on Brain
Distinguished Research Support Award, Otago School of Medical
Sciences Awards
OSMS
47
48
OSMS
RESEARCH REPORT 2011/2012
2011
Professor Allan Herbison
Distinguished Research Medal, University of Otago
2011
Professor Allan Herbison
Triennial Medal, Physiological Society of New Zealand
2011
Professor Allan Herbison
Excellence in Postgraduate Supervision, Otago School of Medical
Sciences Awards
2011
Professor Brian Hyland
Best Paper Award, Otago School of Medical Sciences Awards
2011
Yeri Kim
Freemasons University Scholarship
(BBioMedSc Hons student)
2011
Dr Karl Iremonger
Postdoctoral Research Speaker Award, Otago Medical School
Research Society
2011
Dr Sam Lucas
Fellow Award, 17th International Hypoxia Symposia
2011
A/P Fiona McDonald
Fulbright New Zealand Senior Scholar Award
2011
Rachel Cheong
(PhD student)
John Hubbard Memorial Prize, Queenstown Research Week
2011
Dr Victoria Scott
Young Investigator Award, World Congress of Neurohypophysial Hormones
2011 Dr Daryl Schwenke
Emerging Researcher of the Year, Otago School of Medical Sciences
2011
Malinda Tantirigama
(PhD student)
Student Poster Prize, Division of Health Sciences Research Forum
Malinda Tantirigama
Otago School of Medical Sciences Student Prize for oral presentation at the PhD Colloquium
2011
(PhD student)
2011
Su Young Han
(PhD student)
Poster Presentation Prize, World Congress on Neurohypophysial Hormones
2011
Su Young Han
(PhD student)
Best Student Poster Presentation, Physiological Society of New Zealand, Queenstown Research Week
2011
Rob Porteous
Research Support Staff Award, Otago School of Medical Sciences
2011
Dr Carissa Murrell
Exceptional PhD Thesis, University of Otago
2011
Nairn Smith
Sustained Research Support Staff Award, Otago School of Medical Sciences
2011
Dr Kajsa Igelstrom
Exceptional PhD Thesis, University of Otago
2011
Dr Kajsa Igelstrom
Goddard Student Oral Prize, Australasian Winter Conference on
Brain Research
RESEARCH REPORT 2011/2012
DUNEDIN SCHOOL OF MEDICINE
DSM
49
DEPARTMENT OF GENERAL PRACTICE AND RURAL HEALTH
Head of Department: Associate Professor Chrys Jaye
Email: [email protected]
Website: www.otago.ac.nz/dsm/gp
The Department runs an extensive programme of research in general practice, rural health, medical education, primary
healthcare, respiratory medicine, patient safety and medical anthropology. We have strong links to the Best Practice Advocacy
Centre (BPAC) and an ongoing programme of collaborative research based on the large health databases managed by BPAC.
Major Areas of Research Strength
General practice research
This is a broad research theme that encompasses clinical and professional topics within the discipline of general practice.
Examples of specific areas of research include: childhood obesity; immunisation; doctor/patient relationships; diabetes; health
care fees and charges; and pharmacovigilance.
Rural medicine
Research incorporates issues of rural practice and service provision and includes: the role of the rural hospital generalist and
in particular the interface with base hospital specialists; student attitudes to rural practice; rural hospital services; and rural
hospital cardiology including pre hospital fibrinolysis and management of acute coronary syndromes in the rural setting.
Medical education
This is a major theme with teaching staff actively conducting research into teaching and learning at undergraduate and
postgraduate levels. Areas of research interest include: the hidden curriculum in medical education; communities of clinical
practice; socialisation in medical training; distance learning; professionalism in medicine; evaluation of medical courses and
curricula; education and vocational training for rural hospital generalists; and reflective practice.
External Grants >$5,000 Awarded in 2011-2012
Year PI
Project Title
Funder
$
2011
Prof Susan Dovey Patient safety in New Zealand general practices: Health Research
149,276
Records review study
Council of NZ
2011
Regulating for patient safety in primary care
Dr Katharine Wallis Emily Johnston Scholarship
58,900
2011
Dr Garry Nixon
Provision of cardiac exercise tolerance testing Rural Innovation Fund
50,000
in rural areas
2011
Patricia Boyd How is decision making by whanau altered
Health Research 12,406
when the birth plan is repeat caesarean section Council of NZ
2011
Dr Jim Ross
Lifetime health diaries
Royal NZ College of General Practitioners
5,000
2011
Dr Jim Ross
COMHEART. Community Oriented Mental Royal NZ College of Health: Engagement, Action, Research and General Practitioners
Training
5,000
2011
Prof Susan Dovey
Community-based primary healthcare
networking grants for collaboration with
McMaster University
5,000
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters †
† thesis or dissertation students only
2011
2012
77
67
Health Research
Council of NZ
50
RESEARCH REPORT 2011/2012
DSM
Awards and Honours
Year Recipient
Award
2012
Dr Tony Egan
Australia and New Zealand Association of Health Professional Educators Award
2012
Prof Murray Tilyard
Award for excellence in General Practice research, University of Otago
2012
Patricia Boyd
Mäori Health Research Masters Scholarship, Health Research Council of
New Zealand
2011
Dr Garry Nixon
Pat Farry Award for research excellence in rural health research,
University of Otago
2011
Dr Katharine Wallis
Claude McCarthy Fellowship
2011
Dr Katharine Wallis
Emily Johnston Scholarship for Research in the Science and Art of Medicine
2011
Dr Lik Loh
Clinical Research Fellowship, Dunedin School of Medicine
RESEARCH REPORT 2011/2012
DEPARTMENT OF MEDICINE
Head of Department: Professor Rob Walker
Email: [email protected]
Website: www.otago.ac.nz/dsm/medicine
Collaborative research projects link the Department with others in the Division, as well as other universities in New Zealand
and around the world. Areas of particular research strength include: kidney, rheumatic, cardiac and gastroenterological
diseases, endocrinology, diabetes, ophthalmology, older person’s health, sport and exercise medicine, cancer, and respiratory
illnesses.
Major Areas of Research Strength
Diabetes research
The Edgar National Centre for Diabetes and Obesity Research (ENCDOR) houses New Zealand’s foremost diabetes research
team, involving a range of disciplines, including nutrition, epidemiology, health services research, Mäori health, biostatistics,
public health and social marketing. Research aims to reduce the incidence of diabetes and its complications by finding new
ways to prevent and manage the disease. Studies attempt to address the problem of diabetes and obesity by education, support
and the promotion of healthy lifestyles in both children and adults.
Website: www.otago.ac.nz/diabetes
Respiratory disease
The causes, treatment and prevention of asthma are the central foci of The Otago Respiratory Research Group. Key studies
have revealed that not all asthmatics suffer from the same type of inflammation and not all will respond to commonly used
inhaled steroid treatment. Studies are being undertaken to identify alternative forms of treatment for this group. The group
had previously revealed that long-term cannabis smoking is likely to produce similar adverse effects to tobacco smoking
(chronic bronchitis, emphysema and lung cancer), and that obesity can worsen the impact and severity of asthma.
Kidney disease
Members of this group are dedicated to investigating innovative ways to prevent and treat kidney disease. The group’s
expertise ranges from molecular and cellular-level investigations of kidney function, to applying therapies to prevent kidney
injury or the progression of kidney disease. Efforts are underway to find new markers for early acute renal failure so it can
be treated before irreversible damage or death occurs. Current research projects include: effects of lithium on renal function,
therapeutic targets of polycystic kidney disease, dietary induced obesity and metabolic syndrome, clinical renal trials, renal
function and high performance exercise, and progression of renal disease.
Website: http://kidney.otago.ac.nz
Rheumatology
Major interest centres on the pathogenic pathways of rheumatoid arthritis. This research is attempting to determine the
relationships of this classification to clinical outcomes, pathophysiologic pathways and treatment responses. The genetics of
rheumatoid arthritis and gout is another area of strong research focus. A key project is “Genetics of Gout in Aotearoa” which is
part of a $3.4m HRC programme grant led by Associate Professor Tony Merriman (Biochemistry, OSMS). Other areas of interest
include ankylosing spondylitis, correlates of fatigue in chronic arthritis and scleroderma. With regard to the latter, researchers in
the department contribute to EUSTAR - an international collaborative project to study the natural history of scleroderma.
Gut health
Recent research has suggested that the interaction of the bowel microflora with the intestinal immune system on a specific
genetic background plays a much more significant role in disease than previously anticipated. Many diseases have their origin
in the gut, not only inflammatory bowel diseases, but also certain rheumatological disorders, diabetes, obesity and potentially
many others. Researchers in the department have set up the Gut Health Network to bring together national and international
experts from various fields and disciplines to collaboratively work on these health issues
Website: www.guthealthnetwork.com
Glaucoma
Glaucoma is the number one cause of preventable blindness in New Zealand. The Otago Glaucoma Surgery Outcome Study
is based in the department and is the world’s longest ongoing follow-up study into surgery for glaucoma. Approximately 1400
patients have been followed to determine outcomes following implant surgery or trabeculectomies at Dunedin Hospital since
1976. The electronic database of operations in the Otago Glaucoma Surgery Outcome Study now provides data for studies
aimed at defining the long-term results of glaucoma drainage surgery.
Cardiology
Research in the Cardiology Research Unit involves contributing to multi-centre trials including trials of new devices for
coronary angioplasty and clinical trials of new drugs for management of heart attacks, cholesterol levels and arrhythmia.
Local research includes assessment of biomarkers as predictors of coronary stent re-stenosis after implantation. The unit is
also performing a prospective study in patients with aortic valve disease evaluating what genes might be important in the
development of narrowed heart valves in older persons.
DSM
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RESEARCH REPORT 2011/2012
Oncology
The Oncology Research Group is a predominantly clinical trials-focused group with a portfolio comprising of collaborative,
investigator-led, and commercial trial activity. Recent projects include: the Recharge Study, investigating the use of icecream containing lactoferrin in order to reduce chemotherapy associated diarrhea; the CapTox Study, investigating genomic
predicators of chemotherapy toxicity; and the BRACKIT study, examining predictors of melanoma recurrence from matched
primary lesions and sentinel lymph nodes. The HRC-funded PIPER study is also underway and is the largest study of treatment
and outcomes of colorectal cancer ever undertaken in New Zealand.
Neurology
The Neurology Research Group is involved in research into vestibular disorders, neurodegenerative diseases (including Alzheimer’s and Parkinson’s disease), and augmented reality rehabilitation, multiple sclerosis (ADVANCE/ATTAIN and
PrevANZ studies), medical education research, transcranial magnetic stimulation and the role of cilia in nerve regeneration. External Grants > $20,000 Awarded in 2011-2012
Year PI
Project Title
Funder
$* 2012
A/P Rachael Taylor Prevention of Overweight in Infancy (POI):
Follow-up to 5 years
Health Research Council of NZ
1,198,082
2011
A/P Patrick Manning
Does cabergoline prevent weight regain in people with obesity?
Health Research
1,192,020
Council of NZ 2012
Prof Jim Man
Diabetes Research Foundation Trust University of Otago
2012
A/P Rachael Taylor
Diabetes Research Karitane Products
150,000
Society Ltd
2012
A/P Rachael Taylor
BLISS: is a Baby-led approach to feeding a
suitable alternative?
New Zealand Lottery
88,850
Grants Board
2012
Dr Chris Baldi
Will treating the sympathetic nervous system
prevent diabetic heart disease
HS and JC Anderson
60,524
Charitable Trust
2012
A/P Tony Poole Changes in primary cilia length an function
Queen Mary, 54,387
modulate the pathogenesis of osteoarthritis
University of London
in response to lithium
2012
Prof Tony Molteno
Glaucoma Surgery Outcomes Study
163,358
Healthcare Otago
38,844
Charitable Trust
2012
Prof John Highton
Identification of subtypes of Rheumatoid Otago Medical
34,970
Arthritis through joint and serologic
Research Foundation
characterisation
2011
Prof Robin Taylor
Vitamin D supplementation in the
management of chronic asthma
2011
Dr Kirstin Coppell
The epidemiology of obesity related liver Otago Medical
27,738
damage and hyperuricaemia in the NZ adult
Research Foundation
population – Results from the 2008/2009
NZ Adult Nutrition Survey
2011
Dr Chris Baldi
Myocardial sympathetic responsiveness in
type 2 diabetes
2012
A/P Michael Schultz Translational research into the overlap of HS and JC Anderson
epithelial pathomechanisms of autoimmune
Charitable Trust
diseases
24,472
2011
A/P Michael Schultz
Investigation in inflammation and permeability Healthcare Otago
of the bowel in patients with spondyloarthritis Charitable Trust
20,000
* GST exclusive
Healthcare Otago
29,944
Charitable Trust
Healthcare Otago
24,750
Charitable Trust
RESEARCH REPORT 2011/2012
Commercial Contracts
Year Approved
Organisation
2011-12
Auckland UniServices Ltd
Australasian Gastro-Intestinal Trials Group
Dana-Farber Cancer Institute
Gastrointestinal Cancer Institute (NZ)
University of Queensland
Total
299,215
Postgraduate Students
Total Head Count
2011
2012
PhD
1412
Masters†
78
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2012
A/P Rachael Taylor
Health Research Excellence Publication Award
2012
Dr Kirsten Coppell
Health Research Excellence Publication Award
2012
Professor Jim Mann
Himsworth Award, European Association for the Study of Diabetes
2011
Professor Jim Mann
Honorary Doctorate, North West University, South Africa
2011
Dr Chris Jackson
Freemasons Oncology Fellowship
2011
Dr Kirsten Coppell
Research Publication Award, Dunedin School of Medicine and the Southern District Health Board Health Research Excellence Awards
2011
Tom Highton Award, New Zealand Rheumatology Association
Dr Simon Stebbings
DSM
53
54
RESEARCH REPORT 2011/2012
DSM
DEPARTMENT OF PATHOLOGY
Head of Department: Professor Ian Morison
Email: [email protected]
Website: www.otago.ac.nz/dsm/pathology
The department has a strong research culture with the major themes being cancer, developmental biology and molecular
pathology. Much of the research is multidisciplinary in approach, is clinically relevant, and involves collaboration with
clinical and scientific colleagues in other Departments within the School, University or elsewhere in New Zealand, as well as
international links.
The Department houses a number of research groups: the Cell Transformation Group (PI: Braithwaite), Epigenetics and
Cancer (Morison), the Developmental Genetics and Pathology Group (Eccles), the Chromosome Structure and Development
Group (Horsfield), the Molecular Genetics Laboratory (Markie), the Immune Therapeutics group (Young), and the Molecular
Pathology Group (Fitches).
Major Areas of Research Strength
Cancer research
A major research theme in the Department is cancer research. The over-arching interest of the department is the
identification, characterisation and functional analysis of genes that contribute to the development of cancer. This includes
genes responsible for rare inherited predispositions to cancer, as well as genes that are defective in the more common sporadic
forms of cancer. There is a strong focus on identifying suitable ‘markers’ for cancer diagnosis. These markers are useful in
screening large populations, in detecting patients with cancer at an early stage, and in monitoring patients after treatment for
recurrence. In addition, there is a focus on developing new therapies for treating cancer. Cancers that are being studied include
colorectal, breast, and brain cancer, melanoma, leukaemia, lymphoma and myelodysplastic syndrome. A particular emphasis is
also placed on the function of specific cancer genes, such as TP53, TES, MYCN, and YB-1 and in cancer vaccine development.
Developmental genetics
Several research groups have a strong interest in developmental genetics. Research currently includes:
•
•
•
Developmental biology of the kidney and urinary tract, and associated diseases.
Cell survival and developmental mechanisms in cancer and identification of therapeutic targets for cancer treatment.
The use of developmental models to determine the regulation and function of genes involved in both development and
disease including: RAD21/MYCN, cell growth and breast cancer; PAX genes, embryonic development and cancer; TES,
blood development and leukaemia; polycystic kidney disease genes; cohesin proteins and Cornelia de Lange syndrome.
Chromosome structure and epigenetics
The architecture of normal chromosome during the cell cycle, and the modification of genes by epigenetic marks can also
contribute to changes gene expression, animal development and cancer. Foci of research include: exploring the functions of
the chromosomal glue, cohesin, in its switching of gene activity; the role of epigenetic modification in the development and
function of the placenta; epigenetic silencing as a mechanism of leukaemia gene silencing and as a marker for cancer.
Zebrafish as a model of human disease
Groups both within and the outside the Department make extensive use of the Otago Zebrafish Facility that is directed by Dr
Julia Horsfield. Since there is high conservation of developmental genes throughout evolution, zebrafish provide an amenable
vertebrate animal model. Zebrafish are being used to determine the function of cohesin, testin, YB-1 and many other proteins
important in developmental disorders and cancer.
Website: www.otago.ac.nz/zebrafish
Genetics of human disease
Several of the Department’s researchers have expertise in the discovery of the genetic contribution to human disease, such as
genetic influences on bipolar disorder, gene mutations in polycystic disease, mutations in congenital malformation syndromes,
and mutations in familial and acquired cancer.
RESEARCH REPORT 2011/2012
External Grants > $40,000 Awarded 2011-2012
Year
PI
2011
Dr Julia Horsfield
Project Title
Funder
$* Linking cell division with differentiation: is stem Royal Society of
860,870
cell fate sealed by cohesin?
New Zealand – Marsden
2011
Prof Antony BraithwaiteThe p53 tumour suppressor and its nemesis – Royal Society of 747,826
does a p53 isoform promote cancer through an New Zealand – Marsden
inflammatory pathway?
2011
Prof Ian Morison
NRCGD: Placental and developmental
TEC (subcontract)
epigenetics
2012
Prof Ian Morison
The exposome, the placenta and fetal growth
restriction
461,219
Bill and Melinda Gates
351,470
Foundation (subcontract)
2011
Prof Antony BraithwaiteRegulation of the cell cycle by the oncoprotein YB-1
Cancer Society of
247,967
New Zealand
2011
Dr Julia Horsfield Cancer Society of
240,167
New Zealand
Targeting the oestrogen-cohesin pathway in
breast cancer
2011
Prof Ian Morison
Hypomethylation in the human placenta
University of Auckland
162,481
– NRCGD
2011
Freemasons New Zealand
Dr Sarah Young
The Freemasons Oncology Fellowship
135,000
2012
Prof Antony BraithwaiteHow a p53 isoform causes hyperplasia
Genesis Oncology Trust
and cancer
102,885
2011
Prof Ian Morison
Testin: A novel therapeutic target for Cure Kids
childhood ALL?
102,307
2012
Prof Ian Morison
Advanced digital tissue analysis using the
Aperio Biomedical Imaging system
New Zealand Lottery
100,000
Grants Board
2012
Prof Antony BraithwaiteThe role of p53 isoforms in the promotion
University of Auckland
of tumour invasion, angiogenesis and
metastases
93,188
2012
Dr Sarah Young
Immune therapies for Cancer – Flow
Freemasons New Zealand
Cytometer
70,000
2011
Prof Mike Eccles
Development of a microparticle vaccine
Cancer Society of
50,000
adjuvant RNAi conjugates for selective delivery New Zealand Inc
of immunomodulatory RNAi to dendritic cells
2011
Prof Ian Morison
Targeting childhood leukaemia through the Genesis Oncology Trust
TESTIN pathway
48,220
2011
Dr Noelyn Hung
Early cancer genesis: Telomere mechanisms
and markers
46,546
Genesis Oncology Trust
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
Seperex Nutritional Ltd
30,940
DSM
55
56
RESEARCH REPORT 2011/2012
DSM
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
1620
66
† thesis or dissertation students only
Awards and Honours
Year 2011
Recipient
Award
Dr Sarah Young
Freemasons Oncology Fellowship
RESEARCH REPORT 2011/2012
DEPARTMENT OF PREVENTIVE AND SOCIAL MEDICINE
Head of Department: Professor Jennie Connor
Email: [email protected]
Website: www.otago.ac.nz/dsm/psm
The Department of Preventive and Social Medicine constitutes one of the leading centres for public health research in
Australasia. There are a number of major research groups within the Department including: the Injury Prevention Research
Unit (IPRU), the Dunedin Multidisciplinary Health and Development Research Unit (DMHDRU), the Hugh Adam Cancer
Epidemiology Unit (HACEU), the Ngäi Tahu Mäori Health Research Unit, the AIDS Epidemiology Group, the Cancer Society
Social and Behavioural Research Unit (SBRU), the Centre for International Health, and the Centre for Health Systems. The
New Zealand Pharmacovigilance Centre (NZPC), and the National Poisons Centre (NPC) are also housed in the Department.
Major Areas of Research Strength
Lifecourse research
The Dunedin Multidisciplinary Health and Development Research Unit (DMHDRU) conducts the Dunedin longitudinal
study, one of the most detailed studies of human health and development ever undertaken. A multidisciplinary, longitudinal
study of 1,037 babies born in Dunedin during 1972/73, the Study members have been followed up since birth, at age three,
then every two years to age 15, and at ages 18, 21, 26, and 32. Age 38 assessments were undertaken in 2010. For each follow-up
phase, the Study members are brought to the Dunedin Unit where they undergo numerous assessments and measures of their
health and development. The main research focus is human development over the lifecourse. Other studies run by DMHDRU
include those of the parents of the original Study Members (Family Health History Study), parenting behaviours of Study
Members (Parenting Study), and the 15-year-old children of Study Members (Dunedin Next Generation Study). The research
will provide ground-breaking information across three generations of New Zealand families. Knowledge gleaned from the
Study has influenced family, child and public health policies and practice nationally and internationally.
The DMHDRU is also a founding partner in the National Centre for Lifecourse Research (http://www.lifecourse.ac.nz)
Website: http://dunedinstudy.otago.ac.nz
Injury prevention
The Injury Prevention Research Unit (IPRU) undertakes research that will contribute to reducing the incidence, severity, and
consequences of injury in New Zealand. Research areas include unintentional and intentional injury, outcomes of injury,
and injury prevention. Studies may be based on settings where injury occurs, such as in transport, sport and recreation and
work, or on groups within the population who are at risk, such as children, young people, or older people. Injury surveillance,
examination of cross cutting issues such as alcohol misuse, and the consequences of injury both disability and rehabilitation
are also examined.
Website: https://blogs.otago.ac.nz/ipru
Cancer
The Department has significant expertise in cancer research, with two research Centres dedicated to this field: the Hugh Adam
Cancer Epidemiology Unit (HACEU) and the Cancer Society Social and Behavioural Research Unit (SBRU).
The focus of cancer epidemiology research of the department is the HACEU. The Unit is involved in several national and
international studies of the prevention, causes, impact, burden and consequences of cancer as well as assessments of cancer
incidence, mortality and survival in New Zealand. Recent research includes a nationwide study of prostate cancer, a national
study of bowel cancer, and an investigation into the delay in the diagnosis of cancer in Pacific Island men.
The SBRU is the focus of research into social and behavioural aspects of cancer. To date, it has worked mainly in the priority
areas identified for the primary prevention of cancer in New Zealand, that is tobacco control, healthy physical activity and
nutrition, and ultraviolet radiation exposure. Studies also focus on the psycho-social-spiritual aspects of cancer and cancer
control and health promotion.
Website: http://www.otago.ac.nz/sbrcg
International health
The Centre for International Health is based in the Department. The Centre aims to make a significant contribution to the
understanding, development and well-being of individuals and populations in developing countries. Research projects and
collaborations are underway with other institutes in the Gambia, Indonesia, Samoa and Cambodia.
Website : http://dnmeds.otago.ac.nz/departments/psm/research/international_hlth
DSM
57
DSM
58
RESEARCH REPORT 2011/2012
Hauora Maori
Rangahau hauora Mäori (Mäori health research) is an important part of the research portfolio of the Department. The
goal of the Ngäi Tahu Mäori Health Research Unit is to contribute to the body of knowledge on Mäori health that will lead
to positive health outcomes for Mäori and their whänau. The Unit collects, collates, interprets and publishes information,
data and statistics on Mäori health issues. The major research focuses for the Unit are: hauora rangatahi (young people›s
health); hauora wahine (Mäori women›s health), Mäori and mental health, oranga niho (dental health) and Mäori and injury
prevention.
AIDS epidemiology
The AIDS Epidemiology Group has been responsible for national surveillance of AIDS and HIV infection in New Zealand
since 1989. The aims of the Group are to monitor the epidemic of HIV/AIDS in New Zealand through ongoing surveillance;
to develop, and when appropriate to apply, new methods of monitoring and evaluation; and to contribute to the wider
knowledge of HIV infection and AIDS.
Website: http://dnmeds.otago.ac.nz/departments/psm/research/aids
Health systems
The Centre for Health Systems facilitates and promotes research into health system improvement at the University of Otago,
and across the local and national health systems, as well as internationally. The Centre’s associates come from a range of
University of Otago departments including those spanning our three campuses in Dunedin, Christchurch and Wellington,
as well as the School of Business. It works closely with the Southern DHB and has links with a range of national and
international research groups including the Commonwealth Fund, Boston University Health Policy Institute, and London
School of Economics (Health and Social Care).
Website: http://dnmeds.otago.ac.nz/departments/psm/research/healthsystems
Other research
The Department of Preventive and Social Medicine is a research-intensive department and has a number of other areas of
research strength including: poisons research; pharmacovigilance; environmental health; epidemiology of infectious diseases;
health policy and economics; occupational health; and alcohol-related harm.
External Grants > $40,000 Awarded 2011-2012
Year PI
2012
Prof Richie Poulton Project Title
Funder
$* The Dunedin Multidisciplinary Study of Aging
and Risk for Chronic Disease Health Research 5,665,540
Council of NZ
2012
Prof Peter Herbison Advanced meta-analysis Health Research
970,248
Council of NZ
2011
Prof Richie Poulton
NZVCC Graduate Longitudinal Study
NZ Vice-Chancellors’ 810,000
Committee
2011
Prof Anthony Reeder CSNZ Social and Behavioural Research Unit
– core funding
Cancer Society of 785,000
New Zealand 2011
A/P Brain Cox
Health Research
666,038
Council of NZ Comparative effectiveness research: one-off sigmoidoscopy or iFOBT screening
2012
Prof Philip Hill
TANDEM
European Commission
451,320
(subcontract)
2012
Dr Moana Theodore Health Research
354,513
Council of NZ Te Maramatanga: How education positively
affects Mäori health over time
2011
Prof John Broughton Oranga niho me nga tangata whaiora
Health Research
303,540
Council of NZ 2011
A/P David McBride
Mapua Epidemiological Study
Health Research
270,000
Council of NZ 2012
A/P Kypros Kypri Effects of lowering the minimum alcohol Health Research
263,908
purchase age on traffic crash injury and
Council of NZ
assault rates
RESEARCH REPORT 2011/2012
2012
Dr Ayesha Verrall Tuberculosis and innate immunity: understanding early clearance of infection
Health Research
Council of NZ
232,000
2012
Prof Robin Gauld
Evaluating BSMC on the West Coast
Health Research
199,500
Council of NZ 2011
A/P David McBride
Health Research
120,000
Council of NZ
Occupational health of front line workers
in Christchurch
2011
A/P Nigel Dickson
HIV risks among African communities in
New Zealand
Health Research
98,084
Council of NZ
(subcontract)
2012
A/P Nigel Dickson
HIV Risks and Concerns among African
Communities in New Zealand
Health Research
98,084
Council of NZ
(subcontract)
2012
Dr Mary Jane Sneyd Risk factor heterogeneity for melanom
subtypes: a case-only study
New Zealand Lottery
95,000
Grants Board
2011
Prof Philip Hill
A phase IV effectiveness study of pneumococcalBill and Melinda Gates
61,922
conjugate vaccine in the Gambia
Foundation (subcontract) 2011
Dr Shyamala Nada-Raja Internet-based intervention to improve mental Health Research
58,829
health outcomes for abused women
Council of NZ
(subcontract)
2012
Dr Moana Theodore Whanau Ora: Mäori Household Wellbeing
Regional and Cohort Study
Health Research
58,041
Council of NZ
(subcontract)
2012
Prof Robin Gauld
A study of Systems for Chronic Disease
patient management
Well Dunedin
52,572
Health Trust 2012
Prof Jennie Connor
Alcohol and other risks--National Tertiary Student Survey 2013
Health Promotion Agency
45,624
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
Accident Compensation Corporation
Alcohol Advisory Council of New Zealand
Cancer Society of New Zealand Inc
Central Regions Technical Advisory Services Ltd
City Forests Ltd
Delta Utilities Services Limited
Dow Chemical Company
Massey University
McGill University
Ministry of Business, Innovation and Employment
Ministry of Health
Monash University
Port Otago Ltd
Sapere Research Group
Ministry of Transport
Statistics New Zealand
World Health Organisation
8,201,178
DSM
59
60
RESEARCH REPORT 2011/2012
DSM
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
2320
1014
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2012
Professor Sir David Skegg
Elected President of the Royal Society of New Zealand
2012
Professor John Crump
Bailey K. Ashford Medal, American Society of Tropical Medicine and Hygiene
2012
Dr Rebecca Brookland
Career Development Postdoctoral Fellowship, Division of Health Sciences
2011
A/P Sheila Williams
Health Research Excellence Award, Dunedin School of Medicine and Southern District Health Annual Awards
2011
Dr Sarah Derrett
The Commonwealth Fund (USA) New Zealand Harkness Fellow in Health Care Policy and Practice
RESEARCH REPORT 2011/2012
DEPARTMENT OF PSYCHOLOGICAL MEDICINE
Head of Department: Professor Paul Glue
Email: [email protected]
Website: www.otago.ac.nz/dsm/psychmed
The Department of Psychological Medicine consists of the two main units of Clinical Psychiatry and Behavioural Science. Both
units are involved in a variety of areas of clinically relevant research, with the main themes being mental health epidemiology,
public health, and psychopharmacology. Specific research areas include self-harm and suicide, primary care interventions,
communication and consultation skills, cognitive processes, behavioural aspects of physical health, pain, child abuse,
exploration of developmentally appropriate techniques for gathering information from children, clinical audit, creation of
evidence-based reviews, psychopharmacology and development of novel therapeutics.
In 2010, Professor Paul Glue was a co-investigator on a $2.4 million dollar grant from FRST to assess the effect of Mullerian
Inhibitory Substance on frailty, and in 2012 he was co-investigator on a $970K grant from HRC on Advanced Meta-analysis.
External Grants > $5,000 Awarded 2011-2012
Date PI
Project Title
Funder $*
2011
A/P Kate Scott
The association of mental disorders with
subsequent physical condition onsets
Health Research
643,944
Council of NZ
2012
Dr Tess Patterson
Sexual development in male adolescents:
James Hume
typical and atypical factors and relationship
Bequest Fund
to sexual offending, problematic sexual
behaviour, and mental health and wellbeing
64,767
2011
Prof Paul Glue
Rapid acting antidepressant treatment for
Otago Medical depressed patients with cancer in palliative
Research Foundation
care
6,500
2012
Prof Paul Glue
Second Opinion Study
James Hume
Bequest Fund
6,000
2011
Prof Paul Glue
James Hume
Bequest Fund
5,000
Mood, emotional reactivity and cholinergic
tone in health volunteers
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
98
12
† thesis or dissertation students only
Awards and Honours
Year Recipient
2012
A/P Kate Scott
Award
Research Publication Award, Dunedin School of Medicine and Southern
District Health Annual Awards
DSM
61
62
RESEARCH REPORT 2011/2012
DSM
DEPARTMENT OF SURGICAL SCIENCES
Head of Section: Professor Andre van Rij
Email: [email protected]
Website: www.otago.ac.nz/dsm/surgicalsciences
The Department of Surgical Sciences aims to excel in clinical teaching and training, the linking of basic science with clinical
research and the development of the discipline in New Zealand and internationally. The Department has three major research
units: The Vascular Research Group, the Colorectal Translational Research Group, and the Otago Clinical Audit and Outcomes
Research Group.
Major Areas of Research Strength
Vascular disease
The Vascular Research Group undertakes research in the fields of vascular biology, genetics and physiology. The group has
a wide range of basic science and clinical skills, including molecular biology (genomics, transcriptomics and proteomics),
immunohistopathology, cell culture and vascular physiology (ultrasonography). The group’s primary research interests are:
•
•
•
•
The genetic basis of different forms of vascular disease including abdominal aortic aneurysm, coronary artery disease,
lower limb arterial disease, stroke and varicose veins.
Determining the early processes in the formation of atherosclerosis.
The identification of circulating markers of vascular susceptibility and/or post-interventional outcome.
Determining the pathophysiology of venous disease.
The Vascular Research Group is currently funded by the Health Research Council of New Zealand and is a leading member of
the Vascular Research Consortium of New Zealand (www.vrcnz.org), which aims to support collaborative vascular networks
nationally.
Website: www.otago.ac.nz/dsm-surgery/research/vascular/index.html
Colorectal cancer
The Colorectal Translational Research Group was formed in 2010 to co-ordinate and strengthen existing strands of research
into colorectal cancer and to promote the translation of laboratory discoveries into the clinical environment. It consists of a
collaboration of researchers combining expertise from a broad range of disciplines, including surgery, medical oncology, molecular
biology, bioinformatics, immunology and experimental biology. One of the Group’s core strengths is its clinical base; from which it
procures tissue samples linked to clinical outcome data for laboratory-based research, and recruits patients into clinical trials.
The main research areas are:
•
•
•
•
•
Genetic and epigenetic factors in colorectal cancer
Prognostic tests for colorectal cancer
Immune response to colorectal cancer
Immunotherapy for colorectal cancer
Immune mechanisms in Crohn’s disease
Since its inception in 2010, the Group has procured funding to pursue its strategic goals, has extended its tissue bank and
clinical database, and is initiating several new clinical trials: investigating the role of vitamin D in colorectal cancer and the
management of acute appendicitis.
Website: www.otago.ac.nz/dsm-surgery/research/colorectal-translational-research-group/index.html
Clinical audit and outcomes research
The Otago Clinical Audit and Outcomes Research Group promotes the development of clinical audit within the surgical
profession and develops systems for evaluating longer term outcomes in clinical practice. The Unit has produced significant
research focusing on the process of surgical audit including risk stratification in outcome assessment. A key example of the
Unit’s activities is the development of a successful national system for audit for vascular surgery. Data on 55,000+ patients
is available in the audit database to assist peer-review, to answer enquiries from clinical management, to determine surgical
workloads, to monitor training of registrars and to evaluate overall surgical performance.
Website: www.otago.ac.nz/ouaudit/
Musculoskeletal outcomes research
The Centre for Musculoskeletal Outcomes Research aims to conduct and disseminate research addressing decision-making
and outcomes for patients with musculoskeletal disorders. The centre is a multidisciplinary community of researchers and
clinicians, policy makers and educators dedicated to improving patient health outcomes. This is done through translational
research aimed at optimising clinical practice; from laboratory research through to clinical trials and health services research.
Research interests include orthopaedic pathobiology and biomechanics, clinical diagnostic test and outcome measure
evaluation, occupational and public health issues, clinical epidemiology, economic evaluations and health resource allocation
issues affecting primary and secondary care settings.
Website: http://cmor.otago.ac.nz/
RESEARCH REPORT 2011/2012
External Grants > $20,000 Awarded in 2011-2012
Year PI
Project Title
2012
Prof Andre van Rij
Convergence in surgeons’ clinical judgments
of priority Funder $*
2012
A/P Haxby Abbott
Enhancing the effectiveness of physiotherapy
for individuals with knee osteoarthritis
New Zealand Lottery
91,204
Grants Board
2012
Prof John McCall
Lymphatic Drainage and Prognosis in
Colorectal Cancer
Cancer Society of 75,000
New Zealand Research Trust of 138,786
Victoria University
Wellington
2011
Dr Gerard Wilkins
W and GS Dick Fellowship Southland Medical
73,281
Foundation
2011
A/P Patrick Dawes
The parapharyngeal space: advancing surgical practice through anatomical study
Royal Australasian
56,250
College of Surgeons
2012
Prof Andre van Rij
Circulating markers of metabolic changes
following surgery for morbid obesity
HS and JC Anderson
43,478
Charitable Trust
2011
Prof Andre van Rij
Optimising the screening for Abdominal
Aortic Aneurism
Healthcare Otago
26,087
Charitable Trust
2011
A/P Magnus Thorn The molecular and cellular immunology of regulatory T-cell trafficking in the human body
Healthcare Otago
24,270
Charitable Trust
2011
A/P Magnus Thorn
T-cell trafficking in Crohn’s disease
Otago Medical
Research Foundation
23,679
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
Orchestral Developments Ltd
Southern District Health Board
Synthes New Zealand Ltd
199,502
Postgraduate Students
Total Head Count
2011
2012
PhD
115
Masters 12
†
† thesis or dissertation students only
DSM
63
64
RESEARCH REPORT 2011/2012
DSM
Awards and Honours
Year Recipient
Award
2012
Professor Andre van Rij
Deans Research Medal, Dunedin School of Medicine and the Southern District Health Board Health Research Excellence Awards
2012
A/P Haxby Abbott
Early Career Award for Distinction in Research, University of Otago
2012
Cheng Yee Chan
Richard Stewart Scholarship
(MMedSc student)
2012
Omid Ahmadi
Cancer Society Scholarship
2011
Professor Jean-Claude Theis
Officer of the New Zealand Order of Merit (ONZM) for services to Medicine
2011
Professor Andre van Rij
Colin McRae Medal, Royal Australasian College of Surgeons
2011
Alice Guidera
Australasian College of Surgeons Scholarship
(MMedSc student)
RESEARCH REPORT 2011/2012
DEPARTMENT OF WOMEN’S AND CHILDREN’S HEALTH
Head of Department: Associate Professor Wayne Gillett
Email: [email protected]
Website: www.otago.ac.nz/dsm/wch
The Department of Women’s and Children’s Health comprises the Section of Obstetrics and Gynaecology and the Section of
Paediatrics and Child Health.
The Section of Obstetrics and Gynaecology has diverse research areas, specifically, reproduction and infertility, urogynaecology,
urinary incontinence, contraception, menopause, obesity and weight management in pregnancy, placental pathology and
management of high-risk pregnancy. Staff members are involved with the Cochrane Incontinence Review Group.
Areas of particular research strength in the Section of Paediatrics and Child Health include paediatric pharmacology, sudden
unexpected death syndrome in infancy, sleep in childhood, clinical genetics and clinical ethics.
The Department is also home to: 1) the New Zealand Child and Youth Epidemiology Service (NZCYES); 2) The New Zealand
Mortality Review Data Group (NZMRDG); and, 3) the New Zealand Paediatric Surveillance Unit (NZPSU). These groups are
now known collectively as the CYPRESS Group (Child and Youth Policy, Research and Support Service).
Major Areas of Research Strength
Clinical genetics
Congenital birth defects affect one in every 30 children born in New Zealand and many aspects of their genesis remain a
mystery. The prime thrust of clinical genetics research is the identification of the genetic determinants of congenital birth
defects in children. Disorders under investigation include: the otopalatodigital syndrome spectrum disorders; the Larsen
syndrome-atelosteogenesis spectrum; periventricular nodular heterotopia; osteopathia striata congenita; and De Barsy
syndrome. In addition, the characterisation of new disease genes is a priority. The ethical consequences of the application of
genetic information in the clinical arena are also of interest.
Website: www.otago.ac.nz/dsm/clinicalgeneticsgroup
Sleep in children
Research into children’s sleep evolved from a long interest in understanding normal and abnormal breathing during sleep in
infancy (when the focus was on infants having apparent life threatening events). It has become increasingly clear that in both
adults and children disordered sleep can affect daytime attention span and learning. Studies are currently looking at sleep
and breathing in children with ADHD as there is a suggestion that up to 25% of these children may have disordered sleep
breathing. Sleep duration is also relevant to childhood obesity.
Childhood obesity
Becoming overweight is one of the biggest threats to health in the twenty first century in many countries including New
Zealand. Growth in early childhood sets the pattern for future growth. What babies eat, how they play, and how well they sleep
may all be important in how fast babies put on weight. The Prevention of Overweight in Infancy study is a Health Research
Council funded study designed to work out whether extra information and support for families can improve eating and
activity, encourage better sleep for babies and parents, reduce post-natal depression, improve a family’s well-being and reduces
the rate of excessive weight gain during infancy.
Paediatric pharmacology
The use and effect of drugs is different in children. In collaboration with the School of Pharmacy, and the Department of
Pharmacology and Toxicology, many studies related to drug use in children are under investigation.
Incontinence
The Cochrane Incontinence Group provides a major focus for this research theme within the Department. The goal of the
group is to prepare systematic reviews of the effectiveness of interventions for incontinence, including prevention, treatment
and rehabilitation, concentrating on randomised controlled trials. Other incontinence research within the department falls
within the framework of clinical rehabilitation, with a specific interest in the management of adult urinary incontinence.
DSM
65
66
RESEARCH REPORT 2011/2012
DSM
External Grants > $40,000 Awarded 2011-2012
Year PI
Project Title
Funder
2012
Prof Stephen
Robertson Defining the genetic predisposition to
biliary atresia
Health Research
1,199,327
Council of NZ
2012
Prof Stephen
Robertson
Feeling gravity in your bones: Characterising a
molecular sensor of force
Royal Society of
975,000
New Zealand – Marsden
2012
Prof Barry Taylor
Prevention of Overweight in Infancy (POI):
The Emergence of Self-regulation
Health Research
901,013
Council of NZ
2011
Genetic and functional studies into the
Cure Kids 600,323
causation of malformations in children
Prof Stephen
Robertson
$* 2011
Dr Pamela Jackson
RV3 Rotovirus Vaccine: A Phase 2 clinical trial Health Research
459,000
for a human neonatal rotavirus vaccine for the Council of NZ
global community
2011
Dr Pamela Jackson
RV3 Rotovirus Vaccine: A Phase 2 clinical trial Murdoch Children’s
for a human neonatal rotavirus vaccine for the Research Institute
global community
326,869
2012
Sleep patterns over the first two years of life
Freemasons New Zealand
107,759
2012
Prof Stephen
Robertson
Studying the genetics of biliary atresia
Cure Kids
99,279
2012
Children’s Social Health Monitor
J R McKenzie Trust
96,131
A/P Barbara Galland
Dr Jean Simpson
2012
Dr Pamela Jackson
Impact of rotavirus specific maternal Freemasons of
antibodies on immune response to RV3-BB
New Zealand
rotavirus vaccine within the RV3-BB Phase
IIa clinical trial in Dunedin, New Zealand
82,425
2011
Prof Don Wilson
Markers of regression in cervical Intraepithelial Lady King Scholarship
63,808
neoplasia (CIN2) in young women
2012
Rebekah Luo
Sleep disruption in children: Impact on learning Freemasons New Zealand
and self-regulatory skills
54,286
2011
Rebekah Luo
The role of good self-regulatory skills in children: do they counteract the negative
behavioural learning consequences of sleep
disruption
Freemasons New Zealand
51,779
2012
A/P Barbara Galland
Sleep problems in New Zealand infants: developmental outcomes
New Zealand Lottery
Grants Board
50,000
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Accident Compensation Commission
Bay of Plenty District Health Board
Canterbury District Health Board
Health Quality and Safety Commission
Hutt Valley District Health Board
MidCentral District Health Board
Ministry of Health
Nelson Marlborough District Health Board
Southern District Health Board
University of Sydney
Total
2,362,003
RESEARCH REPORT 2011/2012
Postgraduate Students
Total Head Count
PhD
2011
Masters†
2012
1516
-1
† thesis or dissertation students only
Awards and Honours
Year Recipient
2012
Dr Pamela Jackson
Award
The Royal Australasian College of Physicians, Excellence in Mentoring Award (clinical and professional practice category)
2011
Professor Barry Taylor
Dean’s Research Medal, Dunedin School of Medicine
2011
Dr Margriet van Kogelenberg
Exceptional PhD Thesis, University of Otago
DSM
67
UOC
68
RESEARCH REPORT 2011/2012
UNIVERSITY OF OTAGO, CHRISTCHURCH
DEPARTMENT OF ANAESTHESIA
Head of Department: Professor Edward Shipton
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/anaesthesia
The Department of Anaesthesia has a small but active research programme. Recent areas of interest include volatile
anaesthetic uptake and distribution; acute and chronic pain, and model-based therapies.
Major Areas of Research Strength
Anaesthetic uptake and distribution
The research is diversified, although realistically collaborative research assumes greater importance in a small Department.
Part of the research has been on anaesthetic monitoring particularly with the predictive use of computer modelling. A
computer programme has been developed to model volatile anaesthetic uptake and distribution. The relationship between
calculated effect-site volatile anaesthetic levels and awakening from anaesthesia has been studied. The safe delivery of
anaesthesia has also been examined in patients with mitochondrial myopathies and prolonged QT syndromes. Other
research projects include: effect-site guided opioid administration in the immediate postoperative period; effect of low dose
intravenous premedication on cardiac output and induction of anaesthesia; and estimating the relative potency of morphine
and fentanyl levels by modelling using data from PCA administration.
Pain
An ongoing area of interest is persistent pain and its management. Research focuses on complex regional pain syndrome
(CRPS), post surgical neuropathic pain and chronic pain. The predictors and risk factors in the development of persistent
acute postoperative pain have been looked at as well. The psychosocial adjustment and physical health of children living
with mothers with chronic pain has been explored. The role of parenting as a mediator has been probed. Novel methods of
perioperative pain relief have been developed particularly in the paediatric population with the intranasal route and with
the use of analgesic drops. The comparison of usual surgical advice versus a non-aggravating six-month gym-based exercise
rehabilitation program post-lumbar discectomy with three years of accumulated data has been researched as well. Two
ongoing studies are the effect of pre-emptive gabapentin on chronic neuropathic pain following inguinal hernia repair, and
the efficacy and safety of bisphosphonates in CRPS.
Intensive care
There is collaboration of work on effect site concentrations of volatile and intravenous anaesthetic agents with bioengineering
at Canterbury University. There is potential for feedback loops for target-controlled infusions to be tested in clinical
anaesthesia and in pain medicine. There is active collaborative research in model-based therapeutics in the application
of physiological modelling and computation. This occurs in the following areas, namely: Tight Glycaemic Control and
Specialised Insulin and Nutrition Tables; Metabolic Markers of Critical Illness; Optimising Mechanical Ventilation;
Cardiovascular Modelling; and Control Agitation Sensing and Optimising Sedation Delivery. Other research projects include:
cardiovascular monitoring for circulatory dysfunction; continuous glucose monitoring and subcutaneously delivered insulin
in critically ill patients; and acoustic sensing of ‘crackles’ in patients undergoing mechanical ventilation.
Postgraduate Students
Total Head Count
PhD
Masters †
† thesis or dissertation students only
2011
2012
--
11
RESEARCH REPORT 2011/2012
DEPARTMENT OF MEDICINE
Head of Department: Associate Professor Lutz Beckert
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/medicine/index.html
The Department of Medicine has diverse research interests and hosts a number of very productive research groups. Areas of
research include cardioendocrinology, respiratory research, renal disease, clinical pharmacology, neurology, rheumatology;
and healthcare of the elderly.
Major Areas of Research Strength
Cardioendocrine research
Cardioendocrine research is undertaken by members of the Christchurch Heart Institute. Research is aimed at defining those
plasma neurohormonal measurements, cardiac imaging features, and genotypes which provide the best diagnostic, prognostic
and therapeutic potential for detection and management of heart failure. The Group is also involved in a community heart
study to assess the proportion of Mäori living with undiagnosed heart disease, diabetes, hypertension, high cholesterol or
other significant cardiovascular disease risk factors. The work of the Institute has provided a large bank of practical knowledge
that is used by cardiologists to monitor the prognosis and treatment of patients who have suffered heart attacks. The Group’s
world leading research on natriuretic peptides has contributed to several clinical trials on their use.
Website: www.otago.ac.nz/christchurch/research/cardioendocrine/
Kidney disease
Research is directed towards investigating innovative ways to prevent and treat kidney disease. Expertise ranges from
molecular and cellular-level investigations of kidney function, to applying therapies to prevent kidney injury or the
progression of kidney disease. The aim is to better understand the mechanisms of insult to the kidney, so as to allow earlier
detection and better treatment. Efforts are underway to find new markers for early acute renal failure so it can be treated
before irreversible damage or death occurs. Current research projects include: pathophysiology and early detection of acute
renal failure; roles of apoptosis, growth factors, cell survival genes, nitric oxide and free radicals in acute renal failure; clinical
renal trials, and progression of renal disease.
Website: www.otago.ac.nz/christchurch/research/ckrg
Clinical pharmacology
The clinical application of pharmacology knowledge is the focus of the Clinical Pharmacology Research Group. This Group
includes staff from the Clinical Pharmacology Department at Christchurch Hospital, the Drug Information Service and
the Drug Utilisation Review Service. Current research interests include: pharmacogenetics; drug metabolism in the elderly;
drug use in pregnancy and lactation; antibiotic dosing regimens - especially for the aminoglycosides; phase III drug trials of
gastroenterology drugs; provision of drug information; adverse drug reactions; and thiopurine drugs.
Website: www.otago.ac.nz/christchurch/research/clinicalpharmacology
Rheumatology and immunology
The Canterbury Rheumatology and Immunology Research Group conducts research in the broad field of rheumatic diseases. The
group aims to promote public awareness and support for arthritis, and to improve the standard of care for patients with rheumatic
and immunologic disorders in the Canterbury regions. Research interests include: pharmacokinetics and pharmacogenomics of
disease modifying anti-rheumatic therapies; management of gout; novel markers in early arthritis; and Wegener’s granulomatosis.
Many of the staff involved in this group are members of the University of Otago’s Arthritis Research Theme.
UOC
69
70
RESEARCH REPORT 2011/2012
UOC
External Grants > $40,000 Awarded 2011-2012
Year PI
Project Title
Funder
$* 2011
Prof Mark Richards
Neurohumoral and genetic prediction and protection in heart disease
Health Research
3,430,492
Council of NZ 2011
Prof Lisa Stamp
Safety and efficacy of high dose allopurinol in
the management of gout: a randomised interventional study
Health Research
1,199,225
Council of NZ
2012
A/P Chris Pemberton A novel insulin production diagnostic
Ministry of Business 866,718
Innovation & Employment
2011
Prof Tim Anderson
Multiple Sclerosis Fellowship
Multiple Sclerosis Society NZ
2012
Prof Mark Richards Cardioendocrine research group funding Cardioendocrine 300,000
Research Trust
400,000
2012
Prof Tim Anderson
CHDI sponsored study of Huntington patients, CHDI Foundation
219,005
relatives and controls
2011
Multiple sclerosis imaging research fellow
NZ Brain Research Ltd
2011
Dr Paul Chin
Determining drug clearance for clinically
applicable dosing individualisation
Health Research
151,103
Council of NZ
2011
Prof Tim Anderson
Creatine safety, tolerability and efficacy in
Huntington’s disease CREST-E
National Institutes of 136,667
Health (subcontract)
2011
Dr Anthony Rahman Venous thromboembolism in cancer patients
treated with chemotherapy
Bone Marrow Cancer
108,850
Research Trust
2011
Prof Lisa Stamp
Identifying and overcoming barriers to smoking Health Research
102,779
cessation in rheumatoid arthritis
Council of NZ
2011
Prof Vicky Cameron
Genetics of NZ families with premature
coronary heart disease
2011
Prof Eric Espiner
C-type natriuretic peptide (CNP): a putative
Michael J Fox Foundation
96,432
biomarker of neuronal damage in
for Parkinson’s Research
Parkinson’s Disease
2011
Dr Anna Pilbrow
Molecular mechanisms underlying genetic
susceptibility for heart disease
2012
Dr Toni Pitcher
Parkinson’s disease in New Zealand: Prevalence Neurological Foundation
78,143
and medication consumption
of New Zealand
2011
Dr Nicola Scott
The effect of dietary modification on the
development of the metabolic syndrome
2011
Prof Zoltan Endre
High vs low urine outputs targets in surgical
University of Auckland
69,960
patients: a clinical trial 2012
Prof Tim Wilkinson
The effect of an exercise programme on falls
in older people with depression
Prof Tim Anderson
2012
Prof Bridget Robinson Hypoxic cabinet for cancer research
2011
Prof Zoltan Endre
165,563
National Heart 99,534
Foundation of NZ
Canterbury Medical
87,225
Research Foundation
Canterbury MedicaL
75,906
Research Foundation
Health Research
68,549
Council of NZ (subcontract)
Canterbury Community
60,368
Trust
Multi centre trial of management of biomarkers Australian & New Zealand 59,037
of acute kidney injury Society of Nephrology
2011
Prof Bridget Robinson Tissue bank liquid nitrogen freezer
Lions Club of Christchurch 55,000
Host Charitable Trust
2012
Otago Innovation Limited
A/P Chris Pemberton Signal peptides
* GST exclusive
50,998
RESEARCH REPORT 2011/2012
Commercial Contracts
Year Approved
2011-12
Total
Organisation
Bayer AG Healthcare
BioMarin Pharmaceutical Inc
Canterbury District Health Board
Clinical Network Services (CNS) Pty Ltd
Covance Pty Ltd (Roche)
Massey University
PPD Global Ltd New Zealand
Plant and Food Research
Quintiles Pty Ltd
1,001,968
Postgraduate Students
Total Head Count
PhD
2011
2012
2617
Masters †
66
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2012
Professor Lisa Stamp
Rowheath Trust Award and Carl Smith Medal, University of Otago
2012
Dr Suetonia Palmer
L’Oreal Australia and New Zealand Women in Science Fellowship
2012
Dr Joanna Young
Exceptional PhD Thesis, University of Otago
2011
A/P Chris Pemberton
Liley Medal, Health Research Council of New Zealand
2011
A/P Richard Troughton
Rowheath Trust Award and Carl Smith Medal, University of Otago
2011
Professor Evan Begg
Gold Medal for Research, University of Otago, Christchurch
2011
Dr Michael MacAskill
Outstanding Teaching Award, University of Otago, Christchurch
2011
Dr Anna Pilbrow
Sir Charles Hercus Health Research Fellowship, Health Research Council of New Zealand
2011
Professor Tim Wilkinson
Visiting Professor Medal, Australian and New Zealand Society for
Geriatric Medicine 2011
Career Development Postdoctoral Fellowship, Division of Health Sciences
Dr Tracy Melzer
UOC
71
72
RESEARCH REPORT 2011/2012
UOC
DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY
Head of Department: Associate Professor Peter Sykes
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/obgyn
The Department of Obstetrics and Gynaecology has a number of established research projects in progress which are funded
from a variety of sources. The main themes are gynaecological cancer; reproductive steroids in cardiovascular disease;
endocrine regulation of reproduction; and maternal and fetal medicine.
Staff are members of a number of advisory bodies, serve on a variety of grant assessing committees including the HRC, are
guest editors of international journals, present invited talks at international conferences and peer review journal submissions
and grant applications.
Major Areas of Research Strength
Gynaecological cancer and precancer
The department is closely affiliated with the regional gynaecological cancer service as well as local colposcopy and pathology
services. Such collaborative links permit bench to bedside research. The department takes part in, and leads, international
multicentre clinical trials, local clinical trials, retrospective clinical studies and commercial research.
Cell and protein regulation
The Laboratory for Cell and Protein Regulation is interested in characterising the communities of chemical factors that make
up physiological systems and to describe the dynamic interactions that occur. The main research themes are gynaecological
cancers, endocrine regulation of reproduction, female fertility, and assessment of fetal welfare. The research is undertaken in
collaboration with other scientists both locally and internationally in basic science and clinical areas. There have been longstanding interactions with the Schools of Biological Sciences and Engineering at the University of Canterbury with whom we
hold a Marsden Grant.
Website: www.otago.ac.nz/christchurch/research/cellproteinregulation
Maternal and fetal medicine
Research covers both maternal and fetal health and outcomes. One area of research interest is database development. Ongoing
data is collected for the (i) Fetal Medicine Clinical Unit which reviews women with complicated fetal problems or those at
risk for them, and the (ii) Maternal Medical Clinic where women with underlying medical problems attend. This enables both
audit and follow up of specific cases. The Department is also running two substantial local studies exploring the prognostic
value of HbA1c and C-type Natriuretic Peptide (CNP) in pregnancy. Researchers in the department are also involved in
multicentre trials related to control of hypertension in pregnancy, preterm birth and predictors of preeclampsia.
Website: www.otago.ac.nz/christchurch/research/maternalfetalhealth
External Grants > $10,000 Awarded 2011-2012
Year PI
2011
A/P Peter Sykes
Project Title
2011
Interactions between cells and substrates
Prof John Evans
Funder
$*
PRINCess: The prediction of regression in
Cancer Society of 107,173
CIN2. A prospective multicentre trial of New Zealand Inc
conservative management of CIN2 in
women under the age of 25
MacDiarmid Institute
102,159
2011
Prof John Evans
Mechanisms of hormone storage inside
neurons: novel hypotheses
Royal Society of 67,788
New Zealand
(subcontract)
2011
Prof John Evans
Intersection of nanoscience and biology
MacDiarmid Institute
49,837
2012
Dr Gloria Evans
Endometrial biomarker assessment IVFdx
Otago Innovation Limited
33,061
Gynaecological Cancer Research Trust
10,000
2012
A/P Peter Sykes
Research data coordinator
* GST exclusive
RESEARCH REPORT 2011/2012
Commercial Contracts
Year Approved
Organisation
Onegenetix Ltd
Roche Diagnostics
University of Sydney
Total
134,100
Postgraduate Students
Total Head Count
PhD
Masters
†
2011
2012
43
11
† thesis or dissertation students only
Awards and Honours
Year Recipient
2012
Dr Ruth Hughes
Award
Australasian Diabetes in Pregnancy Society, Graz Clock Award for best clinical presentation and research
2012
Dr Ruth Hughes
Society of Obstetric Medicine of Australasia and New Zealand, President’s Award for best clinical presentation and research
UOC
73
74
RESEARCH REPORT 2011/2012
UOC
DEPARTMENT OF ORTHOPAEDIC SURGERY AND MUSCULOSKELETAL MEDICINE
Head of Department: Professor Gary Hooper
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/orthomsm/index.html
The Department of Orthopaedic Surgery and Musculoskeletal Medicine is unique in New Zealand in that both the Academic
and Service Departments are combined so that the surgical and medical components of musculoskeletal diseases and injuries
come under the roof of one department.
Major Areas of Research Strength
Tissue engineering and Regenerative Medicine
Tissue engineering and regenerative medicine strategies which aim to combine a patient’s own cells, biodegradable scaffolds
and growth factors may offer considerable advantages over current surgical interventions used to repair or regenerate
damaged tissues following trauma or disease. This is the focus of the Christchurch Regenerative Medicine and Tissue
Engineering Group (CReaTE). Using advanced 3D scaffolds and in-vitro culture techniques, combined with adult human
stem cells, our group is attempting to identify the complex cellular environments controlling tissue growth in 3D. We are
also researching their application in translating cell-based therapies to the clinic. Areas of particular research interest include:
articular cartilage and bone regeneration, advanced scaffold design and biofabrication, orthopaedic medical device design and
research related to spine and total joint arthroplasty interventions.
Prospective clinical outcome studies
Studies underway are mainly long term prospective outcome studies on various types of total joint replacements. In addition
the department is responsible for the National Joint Replacement Register. The Register was established by the New Zealand
Orthopaedic Association in 1997 to record technical information about total hip and knee surgery performed in New Zealand
including patient outcome measures. There are now over 52,000 procedures registered. These include primary and revision
hips, knees, ankles, elbows and shoulders.
Monitoring outcomes of joint replacement
Several collaborative studies investigating varied outcome measures are underway including: joint replacement revision due
to infection (Pathology/Infectious Disease Departments, UOC), bone density adjacent to implants (Health Care of the Elderly
Department), acoustic monitoring of implants (Engineering, University of Canterbury), as well as ongoing assessment of wear
in implants with different articulations.
Reconstructive upper limb surgery for tetraplegia
Reconstructive surgery for tetraplegia has been carried out at the Spinal Injuries Unit at Burwood Hospital since 1982.
The Unit is now one of the leaders in the world, not only for the surgery itself but also for outcome studies including the
development of new surgical procedures. An active research programme includes studies into: changes in tendon length
during postsurgical rehabilitation; development of a device for accurate measurement of joint torque; patterns of shoulder
motion; and wheelchair kinematics.
External Grants > $10,000 Awarded 2011-2012
Year PI
Project Title
Funder
$* 2012 Dr Tim Woodfield
New frontiers in musculoskeletal regenerative Rutherford Discovery
800,000
medicine: Biofabrication of cartilage and bone Fellowship, Royal
for entire joint resurfacing
Society of NZ
2012 Dr Sumit Lal
Titania nanoparticle targeted theranostics Genesis Oncology Trust
for breast, colorectal and prostate cancer
2012 Dr Tim Woodfield
skelGEN (FP7-PEOPLE-2012-IRSES) – Establishment of a cross continent consortium
for enhancing regenerative medicine in
skeletal tissues.
164,223
Marie Curie/European
150,000
Commission, International
Research Staff Exchange
Scheme
2012
Prof Alastair Rothwell Postdoctoral Fellowship
Canterbury Orthopaedic
78,657
Services Trust
2011
NZ Wishbone Trust
Prof Gary Hooper
Bone density monitoring of hip replacements
2011
Dr Tim Woodfield
Neural tissue engineering
45,000
Canterbury Orthopaedic
51,000
Services Trust
RESEARCH REPORT 2011/2012
2011
Dr Tim Woodfield
Pre-clinical multi-spectral (MARS) imaging of Arthritis
27,500
cartilage and bone for early detection of New Zealand
osteoarthritis
2012
Dr Tim Woodfield
Equipment grant for sawing microtome
New Zealand Orthopaedic Association 12,438
UOC
75
* GST exclusive
Commercial Contracts
Year Approved
Total
Organisation
Biomet
Orthotec
Plant and Food Research
Synthes New Zealand Ltd
University of Auckland
University of Canterbury
584,596
Postgraduate Students
Total Head Count
PhD
Masters †
2011
2012
22
1-
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Tim Woodfield
Rutherford Discovery Fellowship, Royal Society of New Zealand
2012
Ben Schon
Todd Foundation Award for Excellence
(PhD student)
2012
Dr Sumit Lal
John Gavin Postdoctoral Fellowship, Genesis Oncology Trust
2012
Ben Schon
(PhD student)
Best Poster Prize, Division of Health Sciences Research Forum
2012
Ben Schon
Todd Foundation Award for Excellence
(PhD student)
2011
(PhD student)
Ben Schon
Claude McCarthy Fellowship, Te Pkai Tara Universities New Zealand
76
RESEARCH REPORT 2011/2012
UOC
DEPARTMENT OF PAEDIATRICS
Head of Department: Professor Andrew Day
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/paediatrics
The Department of Paediatrics has an active research programme. Long-established research interests include paediatric
urology especially reflux, community child health, sudden infant death syndrome, and neonatal research. Ongoing research
activities include respiratory medicine, gastroenterology, nutrition, neonatal medicine, infectious diseases and childhood cancer.
Major Areas of Research Strength
Neonatology
The Cure Kids Chair in Paediatric Research is held in the Department by Professor Brian Darlow. Research interests concern
the care of newborn, sick and premature babies, including trying to identify the causes of health problems associated with
premature birth and ways to prevent them. Follow-up studies of the health outcomes of extremely premature infants are also
carried out. A specific interest is free radical disease in the newborn.
Childhood cancer
The Children’s Cancer Research Group is working on a variety of projects, from the basic biology of cancer in children, to the
complex long-term effects of its treatment. Researchers are interested in the biology and genetics of childhood solid tumours.
Current projects involve investigating the molecular genetics of neuroblastomas and hepatoblastomas using microarray gene
expression technology, tissue arrays and protein analysis. More specifically, projects are underway to investigate the role of
histone methylation and DNA methylation in both neuroblastoma and hepatoblastoma, and the role of the sonic hedgehog
developmental pathway in paediatric solid tumours.
Gastrointestinal disorders
In recent years, a new research focus has been developed on host:pathogen interactions within the gastrointestinal tract, with
particular emphasis upon inflammatory bowel disease (IBD) and Crohn’s disease.
External Grants > $10,000 Awarded 2011-2012
Year PI
Project Title
Funder
2012
Prof Brian Darlow
New Zealand very low birth weight young
adults: mapping the road ahead
Health Research 1,150,400
Council of NZ
2012
Prof Brian Darlow
New Zealand very low birth weight adult
Cure Kids
300,000
follow-up study: Project manager
2012
Prof Brian Darlow
New Zealand very low birth weight adult Cure Kids
300,000
follow-up study: MRI scanning and other
support
2012
Crohn’s and colitis in New Zealand children
Cure Kids
2012
Dr Tony Walls
Monitoring the safety of pertussis vaccine
(Tdap) given during pregnancy
Canterbury District 89,500
Health Board
2012
Dr Sarah Harris
N-Terminal Pro B-Type Natriuretic Peptide
Freemasons
48,311
(NT-pBNP) and late pulmonary hypertension New Zealand
secondary to chronic lung disease in
extremely low gestational age neonates
Prof Andrew Day 2012
Prof Brian Darlow
Funding for EndoPAT machine
* GST exclusive
Canterbury Neonatal
Unit Trust
$* 103,379
33,984
RESEARCH REPORT 2011/2012
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
12
2-
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Sarah Harris
Freemasons Research Fellowship
UOC
77
78
RESEARCH REPORT 2011/2012
UOC
DEPARTMENT OF PATHOLOGY
Head of Department: Professor David Murdoch
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/pathology
The Department of Pathology is one of the largest and most research intensive departments at the University of Otago,
Christchurch. Research groups within the Department include: the Free Radical Research Group (FRRG); the Cancer Genetics
Research Group; the Gene Structure and Function Laboratory; the Angiogenesis and Cancer Research Group (ACRG);
the Christchurch Haematology Research Group; the Inflammation Research Group, the Liver Sieve Research Group; the
Christchurch Microbiology Research Group; and the Breath Research Group. The Department also hosts the Carney Centre
for Pharmacogenetics.
Major Areas of Research Strength
Free radical research
Free radical research, carried out in the Centre for Free Radical Research is one of the Department’s major research interests.
The Centre consists of biochemists and cell biologists undertaking a range of interrelated research projects on aspects of
oxidative stress and antioxidant action. Current areas of research include: oxidant production by neutrophils, with emphasis
on the enzymology of myeloperoxidase; the molecular and cellular reactions of the neutrophil oxidant, hypochlorous acid;
mechanisms and consequences of thiol protein oxidation; redox regulation of cell signaling; oxidative stress and apoptosis;
radical scavenging mechanisms and reactions of superoxide radicals. The group has an active programme of developing
biomarker assays for specific oxidants and applying them to investigating oxidative injury in disease. Collaborative clinical
projects include investigations of the role of oxidants in lung disease and brain injury in premature infants, cystic fibrosis,
inflammatory conditions such as asthma, gout and sepsis; and gastrointestinal diseases.
Website: www.otago.ac.nz/christchurch/research/freeradical
Cancer research
The Mackenzie Cancer Research Group is investigating the biology of human tumours with a focus on the molecular
regulation of blood (angiogenesis) and lymphatic vessel formation (lymphangiogenesis) and function during human
tumour growth and metastasis. Specific research interests include: expression and regulation of angiogenic factors in human
cancers; effects of the tumour microenvironment on tumour angiogenesis; targeting tumour endothelium; links between
cancer, inflammation, and thrombosis; ethnicity and cancer biology; metabolism, insulin resistance and chronic low-grade
inflammation in cancer biology; and skin cancers in immune-suppressed renal transplant recipients.
Website: www.otago.ac.nz/christchurch/research/mackenzie/otago011636.html
Gene structure and function
Much of the current research centres on the areas of psychiatric genetics and pharmacogenetics (the impact of genetic
variation on responses to drugs) and is carried out within the Gene Structure and Function Laboratory. The laboratory’s
psychiatric genetics research is a collaboration with Professor Peter Joyce in the Department of Psychological Medicine.
Another important collaboration exists with the Christchurch Health and Development Study. Laboratory expertise includes
DNA banking, gene structure and expression analysis, polymorphism discovery and genotyping, DNA sequence analysis,
tissue culture, proteomics, microarray analysis, and genomics.
Website: www.otago.ac.nz/christchurch/research/genestructure
Inflammation
The Inflammation Research Group has an active research programme on the molecular pharmacology and molecular
pathology of various inflammatory conditions such as acute pancreatitis, polymicrobial sepsis and burns with the long-term
goal of developing clinically effective therapeutic approaches.
Website: www.otago.ac.nz/christchurch/research/inflammation
Infectious diseases
Infectious diseases research is carried out by several clinicians and scientists within the department, and is based both locally
and overseas. Current interests include the epidemiology and microbiology of respiratory tract and bloodstream infections,
the role of vitamin D in infection, and the development of new diagnostics for infectious diseases. The latter includes analysis
of potential biomarkers in breath.
RESEARCH REPORT 2011/2012
External Grants > $40,000 Awarded 2011-2012
Year PI
Project Title
Funder
$*
2012
Prof Tony Kettle
Oxidative stress in health and disease
Health Research
4,242,985
Council of NZ 2011
Prof Margreet Vissers Ascorbate-mediated regulation of HIF-1
controlled tumour growth and angiogenesis
Health Research
812,984
Council of NZ 2011
A/P Mark Hampton
Regulatory cytokine with a built-in redox
773,913
sensor
New Zealand – Marsden
2011
Prof Martin Kennedy
Methylation-stabilised G-quadruplex structures Royal Society of
708,696
as a novel mammalian gene regulation
New Zealand – Marsden
mechanism
2012
Dr Logan Walker
Genetic variation and breast cancer development
2011
A/P Mark Hampton
NRCGD: Biomarkers of mitochondrial TEC (subcontract)
299,420
oxidative stress
Health Research
485,920
Council of NZ 2011
Prof Stephen Brennan Hyper activation of phagocytes by toxic
lipoproteins
Royal Society of
145,178
New Zealand
(subcontract)
2011
NRCGD Depreciation
TEC (subcontract)
Myeloid-derived suppressor cells, immune
suppression and tumourigenesis
Cancer Society of 103,355
New Zealand Inc
A/P Mark Hampton
2011
Dr Margaret Currie
2011
Dr Gabi Dachs
Physiological targeting in cancer therapy
2012
Dr Logan Walker
2012
105,413
Health Research
81,265
Council of NZ
(subcontract)
Copy number variants and BRCA1 associated Canterbury Medical 74,633
breast cancer
Research Foundation
Dr Amy Scott-Thomas Improving the 2-AA breath test for New Zealand Lottery
Ps. aeruginosa detectionGrants Board
72,000
2011
A/P Mark Hampton
SUORG top up – development and testing of Otago Innovation
47,000
2012
Dr Logan Walker Genetic copy number variation and breast cancer development
Cancer Society of
44,220
New Zealand Inc
2012
Prof Bhatia Madhav
Hydrogen sulfide and substance P: Novel
markers of inflammation in rheumatoid
arthritis and gout
Arthritis New Zealand
novel MIF inhibitors: Novel isothiocyanates for Limited
the treatment of murine models of inflammatory
bowel disease
41,469
* GST exclusive
Commercial Contracts
Year Approved
Organisation
Total
AstraZeneca AB
Eli Lilly and Company (USA)
27,004
UOC
79
80
RESEARCH REPORT 2011/2012
UOC
Postgraduate Students
Total Head Count
PhD
2011
Masters†
2012
1516
35
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
2012
Professor Tony Kettle
Award
Professor Christine Winterbourn Companion of the New Zealand Order of Merit
Fellow Royal Society of New Zealand
2012
Dr Logan Walker
Sir Charles Hercus Health Research Fellowship, Health Research Council of New Zealand
2012
Professor Martin Kennedy
Life Sciences/New Zealand Society of Biochemistry and Molecular
Biology Award
2012
Professor Christine Winterbourn Elected Foreign Member of Brazilian Academy of Sciences
2011
Professor Christine Winterbourn Rutherford Medal, Royal Society of New Zealand
2011
A/P Mark Hampton
Gold Medal for Research, University of Otago, Christchurch
2011
Professor Steve Chambers
Gold Medal for Research, University of Otago, Christchurch
RESEARCH REPORT 2011/2012
DEPARTMENT OF PSYCHOLOGICAL MEDICINE
Head of Department: Professor Roger Mulder
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/psychmed
The Department of Psychological Medicine is one of the largest Departments at the University of Otago, Christchurch and has
a very active research programme. The Department hosts a number of research groups including: the Christchurch Health and
Development Study (CHDS); the Mental Health Clinical Research Unit (MHCRU); and the National Addiction Centre (NAC).
Major Areas of Research Strength
Lifecourse research
The Christchurch Health and Development Study (CHDS) has been in existence for more thirty years. During this time it has
followed the health, education and life progress of a group of 1,265 children born in the Christchurch urban region during
mid 1977. This cohort has now been studied from infancy into childhood, adolescence and adulthood. Research projects in
this study span a wide range of disciplines including psychology, psychiatry, epidemiology, paediatrics, health economics
and sociology.
Website: www.otago.ac.nz/christchurch/research/healthdevelopment
Mental health research
The Mental Health Clinical Research Unit (MHCRU) is involved in studies on depression, bipolar affective disorder,
bulimia nervosa, anorexia nervosa, and the psychological effects of the Christchurch earthquakes. Current studies include
a psychotherapy treatment trial in depression, a psychotherapy trial in people with bipolar disorder, a comparison of three
psychotherapies for binge eating, and a study on the genetics of depression and personality.
Website: www.otago.ac.nz/christchurch/research/mentalhealthclinicalresearch
Addiction research
The National Addiction Centre (NAC) is dedicated to developing and promoting effective interventions for people with
alcohol, drug and addiction related problems in Aotearoa New Zealand. Ongoing research projects include: ZonnicTM
and Patch (ZAP) Smoking Cessation Study; Treatment Evaluation of Alcohol and Mood (TEAM) Study; Youth Retention
Study; Odyssey Youth Outcome Study; The Effectiveness of Naltrexone in Reducing the Craving of People with Pathological
Gambling; Resilience in Indigenous Health Networks; Nicotine Study; and Development of Mäori AOD Services and
Workforce in Aotearoa New Zealand.
Website: www.otago.ac.nz/nationaladdictioncentre/
External Grants > $10,000 Awarded 2011-2012
Year
PI
2011
Prof David Fergusson
Project Title
Funder
$*
The Christchurch Health and Development study: Birth to 35 years
Health Research
4,469,202
Council of NZ
2011
Prof Marie Crowe A randomised clinical effectiveness trial of a
bipolar disorder clinic
Health Research
1,189,961
Council of NZ
2011
Prof Roger Mulder
Health anxiety CBT vs TAU for patients with
non-cardiac chest pain
Health Research
726,685
Council of NZ
2011
Dr Cameron Lacey Psychological stress and genetic associations
with stress cardiomyopathy
Health Research
104,918
Council of NZ 2011
Dr Simon Adamson Collaboration with and for rural Mäori with
addiction and related problems
Health Research
60,000
Council of NZ 2012
A/P John Horwood
Prevalence of traumatic brain injury in
New Zealand
Health Research
52,996
Council of NZ
(subcontract)
2012
Katie Douglas Canterbury Medical
Research Foundation
* GST exclusive
Effect of glucocorticoid administration on
brain function in PTSD
41,823
UOC
81
82
RESEARCH REPORT 2011/2012
UOC
Commercial Contracts
Year Approved
2011-12
Total
Organisation
Ministry of Social Development
9,076
Postgraduate Students
Total Head Count
PhD
2011
Masters†
2012
1114
1110
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
A/P Lois Surgenor
Fellow, New Zealand College of Clinical Psychologists
2011
Professor Roger Mulder
Gold Medal for Research, University of Otago, Christchurch
2011
A/P Simon Adamson
SSA Fred Yates Prize Researcher of the Year, Society for the Study of Addiction in York, United Kingdom
2011
Dr Jenny Jones
Fellow, New Zealand College of Clinical Psychologists
2011
Dr Melanie Coker
Exceptional PhD Thesis, University of Otago
RESEARCH REPORT 2011/2012
DEPARTMENT OF PUBLIC HEALTH AND GENERAL PRACTICE
Head of Department: Professor Les Toop
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/phgp
The joint department is unique in New Zealand in that it brings together Public Health and General Practice/Primary Care
teaching and research groups.
Major Areas of Research Strength
General practice research
The Christchurch General Practice Research Group is involved in research into many areas of primary health care in New
Zealand. The Group focuses on clinical research, where the results can be directly translated into clinical practice. The two
central research themes underpinning this are rational use of medicines and innovative models of primary care.
Website: www.otago.ac.nz/christchurch/research/generalpractice
Public health research
Public health is the study and practice of preventing disease, prolonging life and promoting the health of the population
through the organised efforts of society. Research by the Public Health Research Group is carried out in the following
areas: epidemiology, including colorectal cancer control in New Zealand; influenza; health services; health policy; health
determinants; and methodological advances.
Website: www.otago.ac.nz/christchurch/research/publichealth
External Grants Awarded 2011-2012
Year
PI
2012
Dr Phil Hider
Project Title
Funder
$*
Lifting the performance of New Zealand’s
health system. A research collaborative
University of Auckland
790,399
2011
Dr Lee Thompson
Role evolution and community pharmacy in
Canterbury Medical 53,102
Christchurch: perceptions of pharmacists, Research Foundation
GPs and pharmacy users
2011
Prof Philip Schluter
Keep on brushing: improving the oral health
self-care of 18-24 year old beneficiaries
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters†
† thesis or dissertation students only
2011
2012
43
102
Partnership Health
Canterbury
(Te Kei o Te Waka)
3,509
UOC
83
84
RESEARCH REPORT 2011/2012
UOC
DEPARTMENT OF RADIOLOGY AND THE CENTRE FOR BIOENGINEERING
Head of Department: Dr Mike Hurrell
Email: [email protected]
Website: www.chmeds.ac.nz/departments/radiology
The Department has a small but active research programme. Recent research projects include: the development of a national
thoracic aortic stent database to collect and assess data from all implants performed in New Zealand; the development of new
detectors that have applications in medical imaging; and bioengineering and nanomedicine.
Major Areas of Research Strength
Bioengineering and nanomedicine
Researchers in the department are involved in the University of Otago Centre for Bioengineering and Nanomedicine which
was formed in late 2009. The Centre aims to facilitate the commercial delivery of biomedical and scientific innovations for the
benefit of New Zealand and the international community. Research within the Centre at UOC is currently focused on medical
imaging, tissue engineering, and medical computing.
Website: www.otago.ac.nz/bioengineering/
Aneurysm repair
Research seeks to evaluate the safety and efficacy of new devices and techniques in interventional radiology.
External Grants Awarded 2011-2012
Year
PI
Project Title
2011
Dr Anthony Butler
Funder
$*
Spectral analysis with synchrotron for
Royal Society of
15,000
translating spectral CT imaging from
New Zealand
small animal to human use
2011
Dr Nigel Anderson
Spectral CT of fatty liver disease in live mice
Royal Australian and
New Zealand College
of Radiologists
12,748
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters †
2011
2012
36
--
† thesis or dissertation students only
Awards and Honours
Year Recipient
2012
Dr Anthony Butler
Phillips Healthcare Prize, Royal Australian and New Zealand College
of Radiologists
2012
Exceptional PhD Thesis, University of Otago
Dr Paul Ronaldson
Award
RESEARCH REPORT 2011/2012
DEPARTMENT OF SURGERY
Head of Department: Professor Frank Frizelle
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/surgery
Major research interests in the Department of Surgery include emergency medicine; ophthalmology; otolaryngology;
general, oral and maxillofacial, paediatric, vascular, endovascular and transplant surgery; and urology. Another focus is in the
Developmental Genetics Research Group, working in collaboration with Paediatrics.
Major Areas of Research Strength
Helicobacter pylori
A range of projects relating to Helicobacter infection in humans are being carried out by the Helicobacter Research Group.
Current research centres on the gastric pathogen, Helicobacter pylori and the role that small outer membrane vesicles
shed from the bacterial surface play in the development of Helicobacter pylori-associated disease, including gastric cancer.
Investigations into the use of common foods to ameliorate Helicobacter pylori-associated gastric inflammation are ongoing.
The link between the presence of Helicobacter pylori and inflammatory bowel disease, a precursor for colon cancer is also
being studied. Investigations of Mycobacterium avium subsp. paratuberculosis in the aetiology and pathogenesis of Crohn’s
disease are also underway.
Emergency medicine
Research includes diagnostic decision-making research, in collaboration with the Respiratory Medicine and Cardioendocrine
Research Groups and the ethics of resuscitation medicine.
General surgery
The department has considerable expertise in clinically-based research. A number of clinical trials are underway including:
ALCCaS RCT – an Australasian randomised controlled multi-centre trial of laparoscopic versus open surgery for colorectal
cancer; a multicentre RCT on colonic stents versus open operation for stage 4 colorectal cancers; and a multicentre RCT of
laparoscopic versus open surgery for rectal prolapse.
External Grants Awarded 2011-2012
Year
PI
2012
Keenan Jacqueline
Project Title
Funder
$*
Toxin-producing strains of Bacteroides fragilis
and colorectal cancer
Genesis Oncology Trust
33,972
* GST exclusive
Commercial Contracts
Year Approved
Organisation
Canterbury District Health Board
Clinical Financial Services LLC
Ministry of Health
Waikato District Health Board
Total
98,045
Postgraduate Students
Total Head Count
PhD
Masters †
† thesis or dissertation students only
2011
2012
21
31
UOC
85
86
RESEARCH REPORT 2011/2012
UOC
Awards and Honours
Year 2012
Recipient
Award
Professor Michael Ardagh
Officer of the New Zealand Order of Merit, ONZM
2011
Professor Michael Ardagh
John Gilroy Potts Award, Australasian College for Emergency Medicine
2011
Dr Tim Eglinton
Roche Best Poster Award, New Zealand Society of Gastroenterology
Annual Meeting
2011
American College of Surgeons International Guest Scholarship
Dr Tim Eglinton
RESEARCH REPORT 2011/2012
CENTRE FOR POSTGRADUATE NURSING STUDIES
Acting Director of Centre: Professor Marie Crowe
Email: [email protected]
Website: www.otago.ac.nz/christchurch/departments/nursing
The Centre for Postgraduate Nursing Studies is actively involved in research around advancing nursing practice and
improving health outcomes for patients nationally and internationally. While there is a nursing emphasis in much of the
Centre’s research, studies may not be exclusively focused on nursing.
Research at the Centre has a focus on person centred care with the goal of minimising the impact of chronic health needs
on people’s lives. Research explores symptom experience, risk assessment, preventative care and symptom control issues,
with particular emphasis on the enhancement of patient self-management strategies. The study of chronic health needs
encompasses a broad spectrum of disease and age groups to include children, families and older people.
External Grants Awarded 2011-2012
Year
PI
Project Title
2011
A/P Whitehead Lisa
Funder
$*
Building research capability: Nursing and
University of Auckland 18,481
allied health
2011
Dr Sandra Richardson Recognising the impact on students of a crisis University of
10,000
event in an educational setting: Developing
Canterbury
response recommendations
2011
Dr Mary Gagan
Nurse practitioner job satisfaction and
anticipated turnover in New Zealand
New Zealand Nursing Education and Research
Foundation
* GST exclusive
Postgraduate Students
Total Head Count
PhD
2011
Masters †
2012
1010
2641
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Virginia Jones
Strategy to Advance Research (STAR) Postdoctoral Fellowship
2012
Dr Sandra Richardson
Distance Education Association of New Zealand DEANZ Award
Associate Professor Lisa Whitehead from the Centre for
Postgraduate Nursing Studies is interested in family
centred care and the self-management of long-term
conditions especially in diabetes and cancer.
660
UOC
87
UOW
88
RESEARCH REPORT 2011/2012
UNIVERSITY OF OTAGO, WELLINGTON
DEPARTMENT OF MEDICINE
Head of Department: Associate Professor Stewart Mann
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/medicine
The Department of Medicine is active in many areas of medical research including disease mechanisms, new treatments
and clinical trials of treatments. The Department is home to three major research groups which are reflected in the areas of
research strength detailed below. Other academic staff in the department also participate in research appropriate to their
subspecialty, either individually, or in collaboration with other departments or outside bodies.
Major Areas of Research Strength
Rehabilitation
Research into the process and outcomes of rehabilitation is conducted at the Rehabilitation, Teaching and Research Unit
(RTRU). Research is aimed at improving the quality of life of people with disabilities in New Zealand. Specific interests
include qualitative methodologies, psychometrics, continence, kinetic video games, multiple sclerosis, rheumatic disorders,
theory of mind, stroke, spinal cord injury and family therapy.
Website: www.otago.ac.nz/wellington/study/rehabilitation
Asthma
The Wellington Asthma Research Group’s (WARG’s) research programme covers clinical, biomedical and public health aspects
of allergy, asthma and respiratory research, including studies to understand the causes of these disorders and investigate
novel treatments. The group is also part of the HRC Housing and Health research programme in the, and part of the ASPIRE
network for tobacco control, both in the Department of Public Health and internationally with UCLA Berkeley on studies of
chronic hydrogen sulphide exposure and health.
Website: www.otago.ac.nz/wellington/research/waarg/otago016711.html
Sleep disorders
Sleep research is the focus of WellSleep - a comprehensive sleep investigation centre which carries out diagnosis, treatment and
research into a variety of sleep disorders including sleep apnoea, nocturnal hypoventilation, periodic limb movements during
sleep, narcolepsy, and parasomnias. Recent research topics include: Ethic differences in treatment outcomes for patients with
obstructive sleep apnoea (OSA); the technical performance and patient acceptability home setup polysomnography; effectiveness
and acceptance of different modes of positive airway pressure (CPAP, C-Flex™ and AutoPAP) in severe OSA; cardiovascular
effects of OSA; cardio-ventilatory coupling during sleep in human adults, children and infants; development of healthy sleep
educational material for Mäori; novel measures of insomnia diagnosis; and evaluation of a new milk product for insomnia.
Website: www.otago.ac.nz/wellington/about/services/wellsleep/index.html
External Grants > $30,000 Awarded 2011-2012
Year
PI
2011
Dr Kristin Wickens
Project Title
Funder
$*
A maternal probiotic intervention for infant allergic disease prevention
Health Research
1,181,991
Council of NZ 2011
Dr Tristram Ingham
Whiti Te Ra: The contribution of housing conditions to bronchiolitis disparities
Health Research
1,157,725
Council of NZ 2012
Dr Bernadette Jones Asthma health literacy and Mäori
Asthma Foundation
149,999
(subcontract)
2012
Dr Caroline Shorter Fungal spore and allergen reduction using
a PCO device
BRANZ
120,000
2011
Dr William Levack
The process and experience of family carers
managing nursing procedures at home
Health Research
Council of NZ
85,000
2011
Dr Jean Hay-Smith
Disability foundations: Anxiety and injury
perceptions after upper limb trauma
Health Research 85,000
Council of NZ
2011
Dr William Levack
Pulmonary Wii-habilitation: A pilot study
Health Research
Council of NZ
81,686
RESEARCH REPORT 2011/2012
2012
Dr Will Taylor
Award for the development of gout classification criteria
American College
73,903
of Rheumatology
2012
Dr Will Taylor
ACR-EULAR Revised Classification Criteria for Arthritis
49,346
Gout – New Zealand data collection arm
New Zealand
2012
Dr Angela Campbell Sleep health education in Mäori: A local intervention study
New Zealand Lottery
Grants Board
47,502
2012
Prof Julian Crane
A new measurement system for fungal exposure: Are levels of qPCR fungi linked to
new onset asthma in NZ children?
Asthma Foundation
33,831
* GST exclusive
Commercial Contracts
Year Approved
Organisation
Total
Fonterra Co-operative Group Limited
Massey University
Metabolex Inc
Ministry of Health
Synlait Milk Limited
University of Auckland
371,426
Postgraduate Students
Total Head Count
PhD
Masters †
2011
2012
1919
2316
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Janet McDonald
Health Research Council, Disability Research Placement Programme Grant
(PhD student)
2011
Dr Rob Griffiths
John Stoke Memorial Prize, Australia and New Zealand Society of Occupational Medicine
2011
Dr Pauline Boland
Best Abstract in Postgraduate Neurology, Australian Occupational Therapy Association Conference
2011
Best Emerging Researcher, New Zealand Rehabilitation Conference
Dr Pauline Boland
2011
Dr David Powell
Master’s Award, New Zealand Region of the Guild of Air Pilots and
Air Navigators
2011
Best Oral Presentation, Australian Rehabilitation Nurses Association 21st
Annual Conference
Elaine Tyrrell
(Masters student)
UOW
89
90
RESEARCH REPORT 2011/2012
UOW
DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY
Head of Department: Professor Kevin Pringle
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/obstetricsgynaecology
Research interests in the Department of Obstetrics and Gynaecology are varied and include fertility and assisted reproductive
techniques, endometrial cancers, renal disorders, prenatal diagnosis and therapy, endometriosis, incontinence following
delivery, perinatal outcomes following caesarean section, perinatal pathology, and sudden infant death syndrome.
Major Areas of Research Strength
Reproductive medicine
The Reproductive Medicine team within the Department are involved in collaborative research with the School of Biological
Sciences, Victoria University of Wellington. Studies underway include: the possible regulatory role of proteins from the
human egg in IVF patients undergoing intracytoplasmic sperm injection; a clinical audit of the effectiveness of two different
approaches to the management of infertile patients presenting with anovulation.
External Grants Awarded 2011-2012
Year
PI
2011
Pringle Kevin
Project Title
Funder
$*
Effects of Bladder outlet obstruction on fetal Lambs
The Surgical Research Trust 10,000
* GST exclusive
Awards and Honours
Year Recipient
2012
Professor John Hutton
Award
Distinguished Service Medal, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
RESEARCH REPORT 2011/2012
DEPARTMENT OF PAEDIATRICS AND CHILD HEALTH
Acting Head of Department: Professor Dawn Elder
Email: [email protected]
Website: http://www.otago.ac.nz/wellington/departments/paediatricschildhealth
The members of the Department of Paediatrics and Child Health are committed to conducting high quality research into
common and important childhood diseases and to ensure the knowledge gained is translated into improved adolescent
and child health outcomes. Current research focuses on paediatric infectious disease, vascular complications of diabetes,
hypoglycaemia, genetics of childhood epilepsy, respiratory control in newborn babies and preterm infants, long-term
cardiovascular sequelae of prematurity childhood asthma, eczema and allergy, and the effect of pre- and probiotics on the
development of these disorders.
Major Areas of Research Strength
Epilepsy
The epilepsies are a common group of disorders. A significant proportion of them are inherited and due to genetic factors.
The Wellington Epilepsy Research Group is undertaking research aimed at further delineation of the clinical features
and genetics of epilepsies found in families, and identifying genes for these epilepsies. The overall rationale is that by
understanding the basic molecular mechanisms of the inherited epilepsies we will get a deeper understanding of the disorder,
with implications for diagnosis, prognosis and development of new treatments.
Sleep and breathing
The department is collaborating with colleagues in the Department of Surgery and Anaesthesia on research into measures
of respiratory variability and cardiorespiratory interactions in infants and children. Another area of interest is the cause of
perinatal death and SUDI. Staff are involved with the national SUDI case-control study.
Diabetes
Research in this area involves investigation of the acute and chronic complications of diabetes, particularly their
pathophysiology and early development, and also treatment. The aims of this research are to identify factors involved in the
early pathogenesis of the vascular complications of diabetes, when interventions will have the greatest effect.
Allergy and infectious disease
Recent research has looked at the role of probiotics in preventing infant eczema and atopy; Vitamin D in bronchiolitis;
dampness and fungal spores in childhood wheeze; gut permeability in eczema; the use of exhaled nitric oxide in assessing
asthma control; and effectiveness of allergen desensitisation. There are strong research links in these areas with the Wellington
Asthma Research Group and the Housing and Health Research Programme.
Long-term physiological outcomes after extremely preterm birth
This is a newly developing research area for the department. Initial studies have been completed looking at cardiorespiratory
stability of preterm infants at time of discharge. Long-term follow-up studies looking at the effects of extreme prematurity on
cardiac and respiratory function are being planned both in a preterm infant cohort and in a translational animal model paradigm.
External Grants Awarded 2011-2012
Year
PI
Project Title
Funder
2012
Dr Amanda D’Souza
Healthy public policy for children in NZ: overcoming the obstacles
Health Research
264,928
Council of NZ 2012
Lucie Zwimpfer
Talking to babies in a neonatal intensive care
Hawkes Bay Medical 8,400
unit: The impact of verbal soothing on measures Research Foundation Inc
of infant stress during painful procedures
2011
Dr Tamsin Roberts
What is the best method to monitor the
Hawkes Bay Medical
4,279
severity of ongoing respiratory events in very Research Foundation Inc
preterm infants prior to discharge from the
neonatal nursery?
2012
Dr Berry Max
Donation towards research using an animal
model
* GST exclusive
The Neonatal Trust, Wellington
$*
1,000
UOW
91
92
RESEARCH REPORT 2011/2012
UOW
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
11
1-
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2012
Lucie Zwimpfer
(PhD student)
Fanny Evans Postgraduate Scholarship for Women
2012
Dr Mary Berry
Neonatal Update Young Investigator Award, Imperial College London
2011
Dr Tamsin Roberts
Freemasons Paediatric Fellowship
RESEARCH REPORT 2011/2012
DEPARTMENT OF PATHOLOGY AND MOLECULAR MEDICINE
Head of Department: Dr Diane Kenwright
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/pathologymolecularmedicine
The Department of Pathology and Molecular Medicine is a multidisciplinary unit in which the subdisciplines of haematology,
microbiology, chemical pathology, anatomical pathology and molecular pathology are represented. Current research activities
within the Department focus on the causes and behaviour of various cancers with a specific emphasis on breast, cervix,
kidney, prostrate and bladder malignancy. Dental research and urogenital pathology are also areas of research interest.
Major Areas of Research Strength
Urogenital pathology
Research activities are focussed on the classification, diagnosis, molecular biology, growth kinetics and outcome prediction
for adult and childhood renal tumours. Other areas of research are: the pathogenesis and spread of bladder cancer; the
pathenogenesis, diagnosis and behaviour of testicular tumours and prostate cancer; and progeria kidney.
Molecular pathology
The Wakefield Biomedical Research Unit moved to the department from Wakefield Hospital in 2009. It has a strong research focus
on the molecular basis of the spread of colorectal cancer and the fundamental cause of insulin resistance, type 2 diabetes and obesity.
Prostate cancer research
The Prostate Cancer Trials Unit is a research unit within the department participating in international and local clinical trials
to treat prostate cancer. Research activities are focussed on the classification, in particular the Gleason categories, diagnosis
and effective treatment of prostate cancer.
Dental research
The Dental Research Unit has an extensive research programme investigating dental mineralisation, causes of tooth decay and
oral microbiology. Studies to date include plaque growth and development, regulation of plaque pH, urea metabolism, plaque
mineralisation by calcium phosphates, enamel demineralisation and fluoride effects, antiplaque agents, and the biodiversity
and ecology of dental plaque bacterial communities. The Unit houses a novel computer-controlled ‘multiplaque artificial
mouth’. This allows the development of realistic plaque microcosm biofilm model systems.
External Grants Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2012
Dr David Lamb
Prostate cancer: Protein markers to determine Victoria University, 114,088
which patients require treatment
Wellington
2011
Dr Jonathan Foo
Identification of gene transcription profile
differences in the liver following gastric bypass
surgery in a Zucker diabetic fatty rat model of
obese type 2 diabetes mellitus
The Surgical Research Trust 11,540
* GST exclusive
Postgraduate Students
Total Head Count
PhD
2011
Masters †
2012
66
--
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Professor Brett Delahunt
Fellow, Royal Society of New Zealand
2012
A/P David Lamb
Officer of the New Zealand Order of Merit (ONZM) for services to health
2011
Professor John Carter
Member of the New Zealand Order of Merit (MNZM) for services to Medicine
2011
A/P David Lamb
Life Membership of the Cancer Society of New Zealand
(Wellington Division)
UOW
93
94
RESEARCH REPORT 2011/2012
UOW
DEPARTMENT OF PRIMARY HEALTH CARE AND GENERAL PRACTICE
Head of Department: Associate Professor Sue Pullon
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/primaryhealthcaregeneralpractice
The interdisciplinary research undertaken within the Department informs practitioners and consumers, patients and policy
makers about many aspects of health and primary health care. Our research strengths are in women’s health, mental health,
communication in health care and health services research - with a focus on primary health care.
Major Areas of Research Strength
Women’s health
Many diseases including osteoporosis, depression, breast cancer, menopause and Alzheimer’s disease differentially affect
women. The Women’s Health Research Centre (WHRC) works collaboratively, both internationally and locally, to explore
important health challenges for New Zealand women. Key areas of research focus include: mid-life health, diabetes and heart
disease, health and well-being for young pregnant women, and sexual health. Research is conducted within a kaupapa Mäori
framework. Other areas of interest include: osteoporosis, contraception, fertility, unplanned pregnancy, maternity and health
of the newborn.
Website: www.otago.ac.nz/wellington/research/whrc
Communication in health care
Communication in health care is the domain of the Applied Research on Communication on Health (ARCH) Group, with
a particular focus on effective health professional- patient communication. Major studies to date include the Interaction
Study: Exploring Clinical Decision-Making when Rationing is Explicit (2003- 2005); Tracking Health Care Interactions: PatientProfessional Communication; Understanding Diabetes Management- Tracking Communication in Primary Care (2008-2011)
and Communication in Interpreted Health Encounters (2012-13). Members of the ARCH core group have been collecting
and analysing video recordings of naturally occurring interactions between health practitioners and patients since 2003. These
have now been permanently archived along with various related data in the ARCH Corpus, a searchable digitised collection
of health care interactions and related data for use in interaction analysis and education; this is the first data set of its kind in
New Zealand.
Website: www.otago.ac.nz/wellington/research/arch
Mental health
The Department has a longstanding involvement in mental health care research. Academics from the Department in
collaboration with the Department of Psychological Medicine were responsible for producing the landmark Mental Health in
General Practice (MaGPie) study which described the prevalence, form, course and outcome of common mental disorders
in New Zealand general practices. The Department has also been responsible, together with colleagues from Psychological
Medicine, for the evaluation of the Ministry of Health funded programme of Primary Mental Health Initiatives, the
development of toolkits for primary mental health care and the production of an ultra-brief psychological intervention
for consultation use. The Department is currently involved in two randomised controlled trials in mental health care, the
first of light and exercise therapy in dementia and the second of anti-depressant cessation in general practice. A member of
the Department is also working with a WHO panel involved in the mental health component of the revised international
classification of disease ( ICD-11).
Health services research
A variety of projects and studies in health services research have been completed and include: the evaluation of Mid Central
District Health Board mobile nursing service; Pathways Study; Primary Health Care Nurse Education Nelson Bays Primary
Health Care Report; utilisation of primary health care: analysis of routinely collected data (HURA); performance indicators
in primary care, and the capacity of routine primary care to manage pandemic influenza. The Study of Interprofessional
Practice in Primary care (SIPP) investigating collaborative practice and teamwork is in progress, and is related to evaluation of
interprofessional education for undergraduate health professionals in clinical settings.
Addictive and lifestyle research
The Taboo (Tackling Obesity) study builds on earlier work undertaken by the ARCH group (above). A study on families living
with addiction has just been completed, and an investigation into addictive behaviour education for medical students is in
progress.
RESEARCH REPORT 2011/2012
External Grants > $20,000 Awarded 2011-2012
Year
PI
Funder
$*
2012
A/P Beverley Lawton Diabetes: The impact of maternal care
disparities on Mäori mothers and infants
Health Research
Council of NZ
1,192,365
2011
SAMM AUDIT Part 2
Ministry of Health
648,604
The use of interpreters in general practice: observing consultations
New Zealand Lottery
73,451
Grants Board
A/P Beverley Lawton
2012
Dr Maria Stubbe
Project Title
2012
A/P Beverley Lawton Multi-centre case control stillbirth study
Health Research
56,242
Council of NZ
(subcontract)
2012
DPV Dissemination
CSL Biotherapies (NZ) Ltd 30,000
2012
Dr Roshan Perera
Quality improvement: the right tool for the
right task. A prescription safety pilot project.
Health Quality &
25,000
Safety Commission
2012
A/P Sue Pullon
An observational study of interprofessional
collaborative primary care practice
New Zealand Lottery
Grants Board
A/P Beverley Lawton
23,175
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
KPMG
Ministry of Health
Ministry of Youth Development
Total
59,818
Postgraduate Students
Total Head Count
PhD
Masters †
† thesis or dissertation students only
2011
2012
44
32
UOW
95
96
RESEARCH REPORT 2011/2012
UOW
DEPARTMENT OF PSYCHOLOGICAL MEDICINE
Head of Department: Professor Pete Ellis
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/psychologicalmedicine
The Department of Psychological Medicine’s research programme is configured around several themes relevant to mental
health practice in the New Zealand setting, including:
•
•
•
•
•
•
mental health service delivery and evaluation, including in primary care
the interface between psychological and physical health
social psychiatry
psychiatric epidemiology
suicide
education in the clinical professions.
Major Areas of Research Strength
Psychiatric disorders
These studies include epidemiology, schizophrenia and sleep disorders. This stream includes the epidemiological work of
A/P Kate Scott in connection to Te Rau Hinengaro, The New Zealand Mental Health Survey, part of the WHO World Mental
Health Surveys studies on schizophrenia and sleep disorders.
Interventional therapies
Research activity here ranges from psychopharmacological to cognitive-behavioural therapies and includes work with
consumers and government agencies.
External Grants Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2011
Dr Mark Huthwaite
Health professional Training resource-facilitating Alcohol Healthwatch
42,000
alcohol abstinence in pregnancy
2011
Fiona Mathieson
The impact of postgraduate training in
cognitive behaviour therapy (CBT) on
therapist competence and patient outcome
Oakley Menta Health
Research Foundation
* GST exclusive
Postgraduate Students
Total Head Count
2011
2012
PhD
22
Masters†
--
† thesis or dissertation students only
Awards and Honours
Year 2012
Recipient
Award
Dr Elliot Bell
Fellowship, New Zealand College of Clinical Psychologists
2011
Fiona Mathieson
Beck Institute Scholarship
8,000
RESEARCH REPORT 2011/2012
DEPARTMENT OF PUBLIC HEALTH
Head of Department: Professor Richard Edwards
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/publichealth
For a number of years the main focus of the Department’s research work has been monitoring, understanding and mitigating
inequalities in health. The Department also has research strengths in the areas of housing and health, health inequalities,
sustainable cities, health promotion and policy in relation to tobacco, nutrition and obesity, health service and preventive
intervention prioritisation research, Mäori health, cancer control and screening, infectious diseases and health impact
assessment.
Major Areas of Research Strength
Housing and health
He Kainga Oranga, the Housing and Health Research Programme, seeks to examine and elucidate the links between housing
and health. The aim is to identify and then evaluate housing-related interventions to improve individual, family and
community health. Examples of current studies include: Warm Homes for Elder New Zealanders; Close-contact Infectious
Diseases; Healthy Housing Index; Housing and Childhood Respiratory Illness; Home Injury Prevention Intervention; and
Severe Housing Deprivation.
Website: www.healthyhousing.org.nz/
Professor Philippa Howden-Chapman Directs He Kainga Oranga, the Housing and Health
Research Programme at the University of Otago, Wellington.
Sustainable cities
In 2008, the New Zealand Centre for Sustainable Cities was established by members of the He Kainga Oranga programme.
The Centre is dedicated to providing the research base for innovative solutions to the economic, social, environmental and
cultural development of New Zealand’s urban centres. In 2012, the Centre was awarded $9.2 million from the Ministry of
Business, Innovation and Employment for the Resilient Urban Futures project.
Website: http://sustainablecities.org.nz/
Health inequalities research
The Health Inequalities Research Programme (HIRP) is an HRC funded programme established in July 2005 to explore,
explain and provide solutions for systematic health inequalities in New Zealand. There are eight projects within the HIRP
programme: CancerTrends; Differential Colon Cancer Survival by Ethnicity in New Zealand; Neighbourhoods and Health; the
New Zealand Census-Mortality Study; Socioeconomic Deprivation Indexes (NZDep, NZiDep); SoFIE-Health; SoFIE-Primary
Care; and Unequal Treatment – the Role of Health Services.
Website: www.otago.ac.nz/wellington/research/hirp
UOW
97
UOW
98
RESEARCH REPORT 2011/2012
Health service and preventive intervention prioritisation research
This area of research covers the spectrum from prevention to palliation. A major study is the HRC funded Burden of Disease
Epidemiology, Equity and Cost-Effectiveness (BODE3) study. The aim of this study is to build capacity and academic rigour
in New Zealand in the estimation of disease burden, cost-effectiveness and equity impacts of proposed interventions, and
undertake a range of such assessments. The two subsidiary projects of BODE3 are: the Aotearoa Burden of Cancer and
Comparative Benefit Assessment study (ABC-CBA) and the NZ-Assessing Cost-effectiveness – Prevention (NZ-ACE) study.
Website: www.otago.ac.nz/wellington/research/bode3
Maori
health
The focal point for Mäori health research in the department is Te Röpü Rangahau Hauora a Eru Pömare. The goals of the
Centre are to promote and foster health research by, and for, Mäori and to provide an environment in which Mäori can be
trained in a variety of research techniques. Health disparities and unequal treatment between Mäori and non-Mäori are the
foundation of the Centre’s research. Current research themes include breast cancer screening, cancer incidence and statistics,
ethnicity, caring for young pregnant Mäori women, oral health, rural Mäori health, and access to health services.
Website: www.otago.ac.nz/wellington/departments/publichealth/research/otago019668.html
Tobacco and healthy eating - health promotion and policy research
The Health Promotion and Policy Research Unit (HePPRU) is the hub for policy-oriented research into tobacco, food and
obesity within the department. ASPIRE2025 is the major thrust in terms of tobacco research and policy. This a partnership
between major New Zealand research groups carrying out research to help achieve the Government’s goal of a tobacco-free
Aotearoa by 2025. With regard to food and obesity, investigations are underway into policy-relevant issues in nutrition and
food policy such as food marketing in sport settings and Pacific perspectives on promoting children’s healthy eating.
Website: www.otago.ac.nz/wellington/research/heppru
Cancer control and screening
This is a growing area of research interest within the department. The Group is involved in a range of research and policy
work related to cancer epidemiology and control, and population screening. Their work intersects with that of other research
groups within the Department of Public Health, particularly the Health Inequalities Research Programme (HIRP) and Te
Röpü Rangahau Hauora A Eru Pömare.
Website: www.otago.ac.nz/wellington/research/cancercontrol
Social psychiatry and mental health
The purpose of the Social Psychiatry and Mental Health (SoPop) Group is to contribute to knowledge, policy, and services by
conducting research and teaching in the areas of mental health, mental illness, and suicide prevention. The group takes the
perspective that understanding mental health and mental illness cannot be achieved without acknowledging the social context.
In 2009, over $5 million in funding was received from the Ministry of Health for a Multilevel Intervention Suicide Prevention
trial (MISP). While SoPop maintains a strong association with the Department of Public Health it now exists within the
Dean’s Department, UOW.
External Grants > $30,000 Awarded 2011-2012
Year
PI
Project Title
2012
Prof Philippa
Howden-Chapman Resilient Urban Futures
Ministry of Business
Innovation & Employment
2012
Prof Philippa Howden-Chapman
He Kainga Oranga/Community Housing and
Health Intervention Research Programme Health Research
3,749,138
Council of NZ 2011
A/P Louise Signal
C3 - Cancer Care Journeys and Clinical Decision Making
Health Research
1,198,742
Council of NZ
2011
Prof Michael Baker Southern Hemisphere influenza vaccine
effectiveness research and surveillance
(SHIVERS)
Institute of Environmental 207,007
Science and Research
Limited 2011
Prof Sunny Collings
Found in translation: Implementing a tool for
primary mental health development
Health Research 199,249
Council of NZ
2011
A/P Simon Hales
Community vulnerability, resilience and
adaptation to climate change
Funder
Research Trust of Victoria University
Wellington (subcontract)
$*
9,236,552
153,600
RESEARCH REPORT 2011/2012
2012
Dr Vivienne Ivory
Built Environments and Physical Activity in
NZ Youth (BEANZ)
Health Research Council
111,022
of NZ (subcontract)
2012
Dr Kristie Carter
Alcohol consumption in SoFIE Alcohol Advisory Council
90,000
of New Zealand
2011
Dr Kristie Carter
Social policy change: Impacts on the health
of New Zealanders
New Zealand Lottery
45,000
Grants Board
2011
Climate change adaptation
World Health Organisation 44,187
A/P Simon Hales
2011
Gina Pene
Challenges for Tokelau families managing
Asthma Foundation
40,000
asthma and COPD in maintaining a healthy
environment
2012
Prof Michael Baker
Rheumatic fever: Improving surveillance
in New Zealand
Ministry of Health
2011
Prof Richard Edwards
Evaluation of the tobacco excise increase in
New Zealand
Ministry of Health
32,863
(subcontract)
2011
Frank Pega
Alcohol use in bisexual young people: Identifying risk and protective factors
Alcohol Advisory
Council of New Zealand
38,729
30,000
* GST exclusive
Commercial Contracts
Year Approved
Organisation
Total
Auckland Uniservices Limited
CBG Health Research Limited
Housing New Zealand Corporation
Hutt Valley District Health Board
Ministry of Health
Ministry of Transport
Quigley and Watts Limited
Regional Public Health
Nelson City Council
Statistics New Zealand
652,885
Postgraduate Students
Total Head Count
PhD
Masters †
† thesis or dissertation students only
2011
2012
3835
99
UOW
99
100
RESEARCH REPORT 2011/2012
UOW
DEPARTMENT OF RADIATION THERAPY
Head of Department: Ms Karen Coleman
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/radiationtherapy
The Department has a very varied research portfolio reflecting the interests of staff, ranging from preclinical cancer research
and educational research to research into radiation-induced side effects, cancer patient education and information, self care of
radiation therapists and radiation therapy advanced practice.
Major Areas of Research Strength
Cancer biology
Cancer research is being undertaken in conjunction with the Malaghan Institute of Medical Research and Victoria University
Wellington. The focus is on highly glycolytic cancers that are very aggressive and resistant to radiation and chemotherapies.
One project investigates the mechanism(s) of action of radiosensitization of highly aggressive GBM, by high dose ascorbate in
cell and animal models
Clinical trials
A number of clinical trials for treatment of acute side effects of radiation treatment are being conducted in collaboration with
the Southern DHB, capital and Coast DHB, MidCentral DHB and Auckland Radiation Oncology. Trials include: the use of
soft silicone dressings for radiation-induced skin reactions in women treated for breast cancer; manuka honey for radiationinduced oral mucositis in patients treated for head and neck cancer and cranberry capsules to treat radiation induced cystitis
in men with prostate cancer.
Psycho-oncology
Psycho-oncology is the investigation into the psychosocial impact of cancer and its treatments, and is undertaken in areas with
particular relevance to the radiation therapy profession. The current focus is on the impact of high stress levels experienced
by oncology workers in New Zealand on personal accomplishment, job satisfaction and burnout.
Support of cancer patients during their cancer journey
In New Zealand support and education services for cancer patients and their families are being provided by the Cancer Society
of New Zealand. A series of formal evaluations of one such support and education programme aim to ascertain whether this
programme meets the needs of cancer patients and their support people and whether health providers can be confident in
referring patients to this programme.
Another aspect of the cancer patient journey is the disjointed transition from specialist oncology care to primary healthcare,
provided mainly by general practitioners (GPs). Patients often do not know whom to turn to after they finish hospital care
and experience health problems associated with their cancer or cancer treatments. In particular the role of GPs in patient care
in this setting is unclear. This research aims to determine how GPs and oncologists view the role of GPs in this setting and to
provide a framework for better communication to facilitate a seamless transition from specialist to primary care.
Radiation therapy advanced practice
Advanced practice for radiation therapists is an exciting opportunity to develop skills in areas not traditionally seen as part of
the radiation therapist role. Worldwide, advanced practice has been shown to increase job satisfaction and retention as well as
patient care.
Nationwide surveys in collaboration with the New Zealand Institute of Medical Radiation Technology (NZIMRT) have been
undertaken in 2008 and 2011. All research to date had demonstrated that there is substantial support for the implementation of
Advanced Practice roles in New Zealand and that a Masters degree is considered to be the minimum qualification to underpin
the clinical knowledge of radiation therapy advanced practice. In recent years the University of Otago has implemented two
dedicated postgraduate pathways to provide academic qualifications for radiation therapy advanced practice.
RESEARCH REPORT 2011/2012
External Grants > $5,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2012
Dr Patries Herst
Radiosensitisation of highly aggressive cancers
Genesis Oncology Trust
43,011
by high dose ascorbate
2011
Paul Kane
Evaluation of Living Well Programme in New Zealand
Cancer Society of
11,305
New Zealand Inc
2012
Paul Kane
An investigation of best ways for GPs to
Cancer Society of 11,241
support and inform those affected by cancer New Zealand Inc
under their care
2011
Dr Gay Dungey
Stress, burnout and job satisfaction in oncology Cancer Society
care in New Zealand
Wellington Division
2012
Dr Patries Herst
The effect of high dose ascorbate ± radiation
on tumour progression in an intracranial
mouse glioma model
2012
Dr Patries Herst
The effect of high dose ascorbate ± radiation Neurological Foundation
on tumour progression in an intracranial mouse of New Zealand
glioma model
8,550
2012
Kareen Grimshaw Predicting patient outcomes using biological
Genesis Oncology Trust
modeling for radiation therapy treatment plans
6,105
* GST exclusive
Postgraduate Students
Total Head Count
2011
2012
PhD
-1
Masters --
†
† thesis or dissertation students only
9,360
The Surgical Research Trust 8,990
UOW
101
102
RESEARCH REPORT 2011/2012
UOW
DEPARTMENT OF SURGERY AND ANAESTHESIA
Head of Department: Associate Professor Duncan Galletly
Email: [email protected]
Website: www.otago.ac.nz/wellington/departments/surgeryanaesthesia
The Department of Surgery and Anaesthesia is involved in a range of research fields including clinical cardiovascular
physiology and medicine, surgical practice, anaesthesia, resuscitation, and emergency medicine.
Major Areas of Research Strength
Circulation control (PI S. Tzeng)
• Minimisation of brain injury after stroke
• Effects of alcohol consumption on brain flow regulation
• Influence of tobacco smoking on dynamic cerebral autoregulation
• Mechanisms of cerebral autoregulation
• The cardiovascular effects of renal nerve ablation in resistant hypertension
• Baroreflex sensitivity and cerebral autoregulation in heart failure
Ventricular rhythm disturbances (PI P. Larsen)
• Platelet reactivity and inflammation in ischaemic heart disease
• Technical aspects of interventional cardiology
• Mechanisms of ventricular arrhythmia
• Provision of implantable cardioverter defibrillator therapy
• Applications of novel imaging techniques to aid in diagnostic processes
• Scoring tools for risk stratification in cardiac disease.
Prehospital emergency care (PI A. Swain)
• Does a dual fire service and paramedic response improve survival from community cardiac arrest
• Is survival from community cardiac arrest linked to socioeconomic status or location in the Wellington area
• Extended care paramedics – do they reduce hospital emergency attendances?
• Extended care paramedics – a randomised controlled trial of ECP care versus standard paramedic care
• Extended care paramedics – what do the patients think and what is the clinical outcome of ECP care?
External Grants Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2012
Dr Karen Peebles
Reproducibility of the sit-to-stand manouevre Wellington Medical
to assess baroreflex function Research Foundation
Incorporated
5,746
2012
Dr Shieak Tzeng
Establishment of a sheep model of focal
cerebral ischaemia
Maurice and Phyllis
Paykel Trust
5,000
2012
Michael Harrison
An investigation into the morphology of the
central venous waveform at the onset of hypovolaemia
J Campbell Barrett
Wellington Anaesthesia
Trust
3,600
* GST exclusive
Postgraduate Students
Total Head Count
PhD
Masters†
2011
2012
64
34
† thesis or dissertation students only
Awards and Honours
Year 2011
Recipient
Award
Dr Shieak Tzeng
Early Career Award for Distinction in Research, University of Otago
2011
Dr Shieak Tzeng
Sir Charles Hercus Health Research Fellowship, Health Research Council of New Zealand
RESEARCH REPORT 2011/2012
SCHOOL OF PHARMACY
Dean: Professor Stephen Duffull
Email: [email protected]
Website: http://pharmacy.otago.ac.nz/
The School of Pharmacy has a very active research programme, with disciplines ranging from science to humanities with each
having a strong contextual link to health sciences.
Major Areas of Research Strength
Fundamental drug research
Research in this area includes drug discovery, drug metabolism and drug action to extend the range of drugs available and
to provide a scientific basis for the quality use of medicines and bioactive substances. Specific areas of research include:
computational methods encompassing rational, structure and analogue based drug design techniques, QSAR, drug target
identification and lead optimisation; preclinical assessment of new chemical entities including small molecular weight and
polypeptide bioactives; development of analytical methods for drugs in formulations and body fluids; studies on drugs of
abuse aimed at harm minimisation and for application in forensic toxicology; and pharmacokinetic and toxicity studies on
synthetic bioactives and those extracted from natural sources.
Drug formulation and delivery
Bioactive materials such as drugs, vaccine antigens, pesticides and nutrients cannot be administered in their pure form, but
must be incorporated into biocompatible formulations which maintain their stability and deliver them in a way that achieves
optimal beneficial effects while minimising unwanted side effects. This field has important human, veterinary and agricultural
applications. Research in Formulation and Delivery has been designated a Research Theme by the University of Otago.
Clinical pharmacy
Clinical pharmacy is the area of pharmacy concerned with patient care and the optimisation of medicine use in order to
promote health and wellness, and prevent disease. Research in this area includes biopharmaceutical, pharmacokinetic and
pharmacodynamic strategies to optimise drug therapy in patients; consideration of adverse or toxic events to minimise harm;
the study of special populations; and optimal use of medicines.
Social pharmacy
The underlying theme of this research is to improve access to, and the use of, medicines. Several projects explore medicines
use in the community, a number of which involve using large datasets to examine medicines use by gender, age, ethnicity
and socio-economic status. Other projects look at the extent of medicines wastage in the community and lay people’s
understanding and use of medicines. Staff members have an interest in pharmacy practice in developing countries. Recent
projects investigate the quality of medicines in South Africa, and other staff members have carried out research in the South
Pacific. The evaluation of pharmaceutical policy is also an important theme in the group’s work. Professor Pauline Norris and Dr Simon Horsburgh are investigating access to
prescription medicines in rural and remote communities.
Pharmacy
103
104
RESEARCH REPORT 2011/2012
Pharmacy
External Grants > $5,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2011
A/P Natalie Medlicott From materials to dosage forms for proteins and vaccines
New Zealand Lottery
56,000
Grants Board
2012
Dr Rhiannon Braund
Choosing medications that forgive patients
for being forgetful
New Zealand Lottery
41,800
Grants Board
2012
Dr Shakila Rizwan Cubosomes: Novel lipid-based particulate
Otago Medical 22,500
carriers to improve delivery and efficacy of Research Foundation
anti-epileptic drugs in drug-resistant epilepsy
2012
Development of single dose vaccine implants
Prof Sarah Hook NZPERF
12,687
2011
Dr Joel Tyndall
Targeting emerging fungal pathogens and NZPERF
12,250
combating resistance
2012
Dr Shakila Rizwan
Cubosomes: Novel lipid -based particulate
NZPERF
carriers for drug delivery across the blood-brain
barrier
11,000
2012
Electrospun wound dressing from wine waste
NZPERF
7,015
2012
Dr Arlene McDowell
Improving drug absorption using cell penetrating peptides
NZPERF
6,900
2012
Prof Stephen Duffull Identification of biomarkers of biological ageing to predict drug clearance in the elderly
NZPERF
5,400
Dr Greg Walker
* GST exclusive
Commercial Contracts
Year Approved
Organisation
2011-12
Total
AgResearch
Bomac Laboratories Limited
Douglas Pharmaceuticals Ltd
Innate Therapeutics Ltd
Mastitis Research Centre Ltd
Model Answers Pty Ltd
Riken BioResource Centre
Sanofi Aventis New Zealand Ltd
TB Alliance
Zenith Technology Corp Ltd
627,224
Postgraduate Students
Total Head Count
PhD
Masters†
† thesis or dissertation students only
2011
2012
4441
--
RESEARCH REPORT 2011/2012
Awards and Honours
Year Recipient
Award
2012
Dr Rhiannon Braund
Prime Minister’s Supreme Award for Tertiary Teaching Excellence
2012
Dr Rhiannon Braund
Teaching Excellence Award, University of Otago
2012
Dr Nicky Thomas
Exceptional PhD Thesis, University of Otago
2011
Dr Clare Strachan
Early Career Award for Distinction in Research, University of Otago
Pharmacy
105
Physiotherapy
106
RESEARCH REPORT 2011/2012
SCHOOL OF PHYSIOTHERAPY
Dean: Professor David Baxter
Email: [email protected]
Website: http://physio.otago.ac.nz
Research and knowledge transfer are integral parts of the School’s activities, and these areas continue to develop rapidly. The
School has active research programmes in a variety of rehabilitation related areas, which are managed through the Centre for
Health, Activity, and Rehabilitation Research.
Major Areas of Research Strength
•
•
•
•
Healthy aging
Physical activity and health
Injury prevention and sports concussion
Clinical biomechanics and medical technologies
External Grants > $5,000 Awarded 2011-2012
Year
PI
Project Title
Funder
$*
2011
A/P Leigh Hale
Haua Matau Mäori
Health Research
151,790
Council of NZ 2011
A/P Leigh Hale
Prevention of falls for adults with intellectual
disability (PROFAID)
Health Research
143,062
Council of NZ
2011
A/P Leigh Hale
Low-cost telerehabilitation for people with
chronic stroke
Auckland University
93,758
of Technology
2011
Dr Steve Tumilty Support the chronic care community exercise Well Dunedin 29,546
programme – including diabetes, cardiovascular, Health Trust
respiratory disease and morbid obesity
2011
A/P Leigh Hale
Developing bridges New Zealand
Physiotherapy
19,132
New Zealand
2011
Ben Darlow
Physiotherapy New Zealand
The attitudes and beliefs of New Zealanders
about low back pain
5,410
* GST exclusive
Commercial Contracts
Year Approved
2011-12
Total
Organisation
Fogdog Brands Ltd
Landcorp Farming Ltd
91,800
Postgraduate Students
Total Head Count
PhD
2011
2012
2316
Masters†
97
† thesis or dissertation students only
Awards and Honours
Year Recipient
Award
2011
Professor John Sullivan
Distinguished Researcher Award Outstanding Publisher-Senior, University of Otago School of Physiotherapy
2011
Dr Gisela Sole
Distinguished Research Award for Outstanding Emerging Researcher, University of Otago School of Physiotherapy
107
RESEARCH REPORT 2011/2012
RESEARCH FACILITIES AND SUPPORT SERVICES
The Division hosts the following research support services:
Anatomy Museum and Human Skeletal Collection
The W.D. Trotter Anatomy Museum in the Department of Anatomy was established in 1874 and holds a large collection of
anatomical specimens and models, many of which date back to the late 1800s. The Museum also holds many osteological
specimens and an extensive collection of normal and abnormal radiographs.
The Department has a well-equipped plastination laboratory which provides many of the new material for the Museum’s
collections. A number of plastination techniques are undertaken including the silicone technique for plastinated prosections,
E12 for transparent body slices, and P35 for thin brain slices.
The Department’s anthropological collection of human skeletal material is the largest in New Zealand. Postgraduate students
and staff from any department in the University may apply for research-based access to the Museum and skeletal collections.
Website: http://anatomy.otago.ac.nz
Biostatistical and Bioinformatics Services
The Division and Schools provide professional biostatistical services that are available across the three campuses. Individual
arrangements for accessing the services exist in each School.
Bioinformatics expertise and advice is available through the Department of Biochemistry, especially those problems pertaining
to microarray data. Contact: Dr Mik Black [email protected]. Additional services are available from NZGL, see below.
Centre for Protein Research
The Centre for Protein Research is a facility strongly supported by the Departments of Biochemistry and Microbiology and
Immunology but available to all researchers within the University of Otago. It combines both a service facility and a user
laboratory that supports research projects largely within the Division of Health Sciences. The centre also provide service
analyses for external institutes.
The facility is equipped with contemporary technologies for protein and proteome analyses such as MALDI tandem Time of
Flight and ESI-coupled LTQ-Orbitrap mass spectrometry, different HPLC-systems for peptide and protein separation and
large scale 2-D gel electrophoresis.
Website: http://biochem.otago.ac.nz/cpr/home.html
Histology Unit
The Division houses the Pathology Anatomy Histology Unit (PAHU). The Unit provides histology services for University
researchers as well as outside companies. It also offers diagnostic dental services for the country. The Unit undertakes
processing, cutting and staining of all types of tissue. Routine staining, immunoperoxidase and fluorescent techniques are all
catered for. Qualified Medical Laboratory Scientists are available to advise on all aspects of histology and to instruct users in
either staining techniques or use of equipment. Equipment available for use includes: a cryostat, an embedding machine, a
microtome, staining machines and a light microscope.
Contact: Mandy Fisher, Department of Pathology ([email protected])
Lynda Horne, School of Dentistry ([email protected])
Laser Capture Microdissection
Laser Capture Microdissection is a method for isolating pure cells of interest from specific microscopic regions of tissue
sections. Isolated cells can be used for downstream reactions such as RNA extraction for gene analysis, or protein extraction
and analysis. Facilities are located in the Department of Anatomy.
Contact:Andrew McNaughton ([email protected])
New Zealand Genomics Limited (NZGL)
NZGL is a collaborative infrastructure serving New Zealand scientists. Several of the countries universities and Crown
Research Institutes have pooled their resources in a collaborative national infrastructure designed to accelerate New Zealand’s
genomic research and technology. Otago has led this initiative. NZGL provides genomics technology and bioinformatics
services to underpin research in a broad range of areas, including medicine, agriculture and the environment. Through its
collaborating partners, NZGL offers the following services: next generation sequencing, a microarray service, bioinformatics,
genotyping, and IT cloud for data storage and processing.
Website: www.nzgenomics.co.nz
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Otago Centres for Electron and Confocal Microscopy
The Otago Centre for Electron Microscopy (OCEM) is well-equipped for all conventional electron microscopy applications.
The Centre specialises in a range of cryopreparation techniques (both transmission and scanning electron microscopy) and
immunocytochemical techniques. There are two transmission electron microscopes, a Phillips CM 100TM and a Phillips
EM410 TEM. The scanning electron microscopes are a JEOL 6700F Field emission scanning electron microscope, a Zeiss
Sigma VP FEG SEM, and a Cambridge S360 conventional SEM. The JEOL 6700f is fitted with an Alto 2500 high resolution
cryostage for working with frozen hydrated specimens and an elemental analysis (EDS) system.
The Otago Centre for Confocal Microscopy (OCCM) works in close association with the OCEM. It has a Zeiss LSM 710
confocal microscope and two Zeiss LSM 510 confocal laser scanning microscopes: one configured for fixed, slide mounted
material, the other for live cell investigations. There is an Olympus AX70 research grade microscope configured for brightfield,
phase contrast, darkfield and fluorescence microscopy. It is fitted with a Spot RT 5 megapixel camera and associated software
for digital image capture. The Centres also have other equipment available and a full list can be found on the website.
Website: http://ocem.otago.ac.nz/
Otago Flow Cytometry Facility
The Flow Cytometry Facility provides the University of Otago with fluorescent cell analysis and sorting, magnetic bead
separation and fluorescent protein detection technology. The facility is situated in two locations on the campus. Two
analysers and the fluorescent and magnetic bead based cell sorters, are housed within the Department of Microbiology and
Immunology. The other analyser is housed within the Wellcome Institute. In addition the facility offers a Bioplex machine that
allows researchers to simultaneously analyse multiple analytes, such as cytokines, within biological samples. These can be used
for the analysis of complex cell suspensions: blood cells, bacterial communities, disaggregated tumours, cell cycle analysis.
Contact:Dr AlexMcLellan, [email protected]
PC3 Facility
The Division’s PC3 biocontainment laboratory is located on the roof of the Microbiology and Immunology building. This
facility enables researchers to work directly on human disease causing infections and pathogens. This facility facilitates work in
virology, tuberculosis, and other pathogens..
Contact:Professor Kurt Krause, [email protected]
Protein Crystallography Facility
Professor Krause serves as the Director of the protein crystallography facility within the Division. The facility consists of three
large temperature controlled rooms. One is devoted to crystallisation and contains a new MosquitoTM crystallisation robot.
The second room contains computer control and modelling facilities. The third room contains a MicroMax007HF with an
R-axis IV++ area detector. It is equipped with both chromium and copper anodes and separate optics. Chromium radiation
is used for single wavelength anomalous diffraction (SAD) determination of protein structures, mitigating in most cases the
need to visit a synchrotron. This approach has been effective for proteins with 2% or more S or Se containing residues. The
flux of this machine is roughly equivalent to the protein crystallography beamline at the LSU- CAMD synchrotron facility
in Baton Rouge, La. Cryo-cooling is carried out using a Rigaku X-stream 2000 cooling system. The University is also part
of a consortium that will have regular access to the protein beamlines at the Australia National Synchrotron in Melbourne.
Beamlines there will be optimised for MAD structure determination and native data collection. Researchers interested in pursuing a protein crystal structure determination should email Professor Krause at:
[email protected]
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DIVISIONAL SUPPORT FOR RESEARCH
The Division has a Research Committee, consisting of the Associate Deans of Research from each School plus other
representatives. This Committee meets four or more times annually and controls an annual budget which provides:
•
•
•
•
•
•
•
•
Postdoctoral fellowships
PhD conference travel funding
An annual Divisional Research Forum
Mentoring for targeted grant applications
Review of applications
Oversight of PBRF Evidence Portfolio preparation
Research workshops
Other support as decided
The Committee is Chaired by the Division’s Associate Dean for Research, Professor Catherine Day. The Division employs Dr
Michele Coleman as its Research and Development Manager and Dr Kerry Galvin to support research.
For further information please contact: [email protected]
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UNIVERSITY OF OTAGO RESEARCH AND ENTERPRISE OFFICE
The Research and Enterprise Office deals with research funding and assists researchers in gaining funding from the
application/proposal stage right through to contracting and reporting stages. Research and Enterprise staff provide the liaison
between the funding bodies, industry or businesses and staff at the University. The Research and Enterprise Office deal with a
range of activities including:
•
•
•
•
•
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Research grants, proposals and contracts (externally funded travel and equipment grants)
Fellowships
University of Otago Research Grants
Technology transfer
Intellectual property protection (including patents and trademarks)
Material transfer agreements
Under the auspices of the Research and Enterprise Office, research in the Division of Health Sciences is supported by a number
of Research Advisors and Administrators, and additional staff at the University of Otago, Christchurch and Wellington.
Staff with Health Sciences Responsibilities:
Christine Groves, Research Advisor
University of Otago, Wellington
[email protected]
Rebecca Coombes, Research Manager
University of Otago, Christchurch
[email protected]
Karen Chaney, Research Advisor
University of Otago, Christchurch
[email protected]
Dr Dayle Matthews, Manager
Health Research South, Dunedin School of Medicine
[email protected]
Ali Cameron, Research Advisor
Health Research South, Dunedin School of Medicine
[email protected]
Dr Edwin Meijerink, Research Advisor
Health Research South, Dunedin School of Medicine
[email protected]
Ruth Sharpe, Clinical Research Advisor
Health Research South, Dunedin School of Medicine
[email protected]
Dr Diana Rothstein, Research Advisor (Health Sciences)
Research and Enterprise Office, Dunedin
Dr Natalie Harfoot, Research Advisor (Health Sciences)
Research and Enterprise Office, Dunedin
[email protected]
Dr Eric Lord, Research Advisor (Health Sciences)
Research and Enterprise Office, Dunedin
[email protected]
David Grimmett, Enterprise Manager - Biotechnology
[email protected]
Dr Ruth Appleby, Enterprise Manager – Physical and Biomedical Sciences
[email protected]
Dr Rachel Elliott, Enterprise Manager - Food, Nutrition and Health
[email protected]
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APPENDIX 1: PUBLICATIONS BY SCHOOL AND DEPARTMENT 2011 - 2012
Bioethics Centre
Authored Book - Research
Harland, T., & Pickering, N. (2011). Values in higher education teaching. London, UK: Routledge, 134p.
Nie, J.-B. (2011). Medical ethics in China: A transcultural interpretation. London: Routledge, 276p.
Authored Book - Other
Educational, Scientific and Cultural Organisation UNESCO, including Carmi, A., Evans, D., & De Castro, L. (2011). Casebook
on human dignity and human rights [Bioethics core curriculum casebook series No. 1.]. Paris: UNESCO, 144p.
Educational, Scientific and Cultural Organisation UNESCO, including Carmi, A., Evans, D., & De Castro, L. (2011). Casebook
on benefit and harm [Bioethics core curriculum casebook series No. 2.]. Paris: UNESCO, 140p.
Chapter in Book - Research
Evans, D. (2011). Benefit and harm. In H. A. M. J. ten Have & B. Gordijn (Eds.), Compendium of global bioethics. Springer.
Evans, D. (2011). Resource allocation. In R. Chadwick (Ed.), Encyclopedia of applied ethics (Vol. 3) (2nd ed.) (pp. 813-820). San
Diego, CA: Academic Press. doi: 10.1016/B978-0-12-373932-2.00169-1
Gillett, G. (2012). Spirituality, human flourishing, and disease. In M. Miner, M. Dowson, & S. Devenish (Eds.), Beyond wellbeing: Spirituality and human flourishing (pp. 33-47). Charlotte, NC: Information Age Publishing.
Gillett, G. (2012). How do I learn to be me again? Autonomy, life skills, and identity. In L. Radoilska (Ed.), Autonomy and
mental disorder (pp. 233-251). New York: Oxford University Press.
Hamilton, M., & Gillett, G. (2012). Suffering and the sleeplessness of clinicians. In J. Malpas & N. Lickiss (Eds.), Perspectives on
human suffering (pp. 287-305). Springer. doi: 10.1007/978-94-007-2795-3
Jones, D. G. (2011). The anatomy museum and mental illness: The centrality of informed consent. In C. Coleborne & D.
MacKinnon (Eds.), Exhibiting madness in museums: Remembering psychiatry through collections and display (pp. 161-177).
New York: Routledge.
Jones, G., & Whitaker, M. (2012). Transforming the human body. In C. Blake, C. Molloy, & S. Shakespeare (Eds.), Beyond
human: From animality to transhumanism (pp. 254-279). London: Continuum.
King, M., Whitaker, M., & Jones, G. (2011). Speculative ethics: Valid enterprise or tragic cul-de-sac? In A. Rudnick (Ed.),
Bioethics in the 21st Century (pp. 139-158). InTech. doi: 10.5772/19684
Nie, J.-B. (2011). The “cultural differences” argument and its misconceptions: The return of medical truth-telling in China. In
A. Rudnick (Ed.), Bioethics in the 21st Century (pp. 103-120). InTech. Retrieved from http://www.intechopen.com/articles/
show/title/the-cultural-differences-argument-and-its-misconceptions-the-return-of-medical-truth-telling-in-chin.
Chapter in Book - Other
Jones, D. G. (2011). Introductory essay to Playing God? Genetic determinism and human freedom. In P. K. Das II (Ed.), A companion
to the ISSR library of science and religion (pp. 341-342). Cambridge, UK: International Society for Science and Religion.
Jones, D. G. (2011). Introductory essay to Religion and the rise of modern science. In P. K. Das II (Ed.), A companion to the ISSR
library of science and religion (pp. 413-414). Cambridge, UK: International Society for Science and Religion.
Jones, D. G. (2011). Death, definition of. In J. B. Green, J. E. Lapsley, R. Miles, & A. Verhey (Eds.), Dictionary of scripture and
ethics (pp. 205-206). Grand Rapids, MI: Baker Academic.
Journal - Research Article
Anderson, L., & Bowyer, L. (2012). Engaging the professional community: Rewriting a code of ethics for NZ physiotherapists.
Physical Therapy Reviews, 17(3), 190-196. doi: 10.1179/1743288X11Y.0000000058
Anderson, L., Exeter, D., & Bowyer, L. (2012). Sudden cardiac death: Mandatory exclusion of athletes at risk is a step too far.
British Journal of Sports Medicine, 46, 331-334. doi: 10.1136/bjsports-2011-090260
Anderson, L., & Jackson, S. (2012). Competing loyalties in sports medicine: Threats to medical professionalism
in elite, commercial sport. International Review for the Sociology of Sport. Advance online publication. doi:
10.1177/1012690211435031
Anderson, L., Snelling, J., & Tomlins-Jahnke, H. (2012). The practice of surrogacy in New Zealand. Australian & New Zealand
Journal of Obstetrics & Gynaecology, 52(3), 253-257. doi: 10.1111/j.1479-828X.2012.01419.x
Evans, D. (2012). Whakapapa, genealogy and genetics. Bioethics, 26(4), 182-190. doi: 10.1111/j.1467-8519.2010.01850.x
Evans, D. (2012). Academic freedom and global health. Journal of Medical Ethics, 38(2), 98-101. doi: 10.1136/jme.2010.041251
Franz, E. A., & Gillett, G. (2011). John Hughlings Jackson’s evolutionary neurology: A unifying framework for cognitive
neuroscience. Brain, 134, 3114-3120. doi: 10.1093/brain/awr218
Gillett, G. (2011). The gold-plated leucotomy standard and deep brain stimulation. Journal of Bioethical Inquiry, 8, 35-44. doi:
10.1007/s11673-010-9281-z
Gillett, G. (2011). Minimally conscious states, deep brain stimulation, and what is worse than futility. Journal of Bioethical
Inquiry, 8(2), 145-149. doi: 10.1007/s11673-011-9292-4
Gillett, G. (2011). The death of a living soul. Journal of Law & Medicine, 18(4), 695-700.
Gillett, G. (2011). Living and learning during an ethical crisis in medicine. Journal of Law & Medicine, 19(2), 244-249.
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Gillett, G., & Liu, S. C. (2012). Free will and Necker’s cube: Reason, language and top-down control in cognitive neuroscience.
Philosophy, 87(1), 29-50. doi: 10.1017/s003181911100057x
Gillett, G., & Tamatea, A. J. (2012). The warrior gene: Epigenetic considerations. New Genetics & Society, 31(1), 41-53. doi:
10.1080/14636778.2011.597982
Gillett, G., & Walker, S. (2012). The evolution of informed consent. Journal of Law & Medicine, 19(4), 673-677.
Ho, K. M., Honeybul, S., Lind, C. R. P., Gillett, G. R., & Litton, E. (2011). Cost-effectiveness of decompressive craniectomy as
a lifesaving rescue procedure for patients with severe traumatic brain injury. Journal of Trauma, 71(6), 1637-1644. doi:
10.1097/TA.0b013e31823a08f1
Honeybul, S., Gillet, G. R., Ho, K. M., & Lind, C. R. P. (2011). Neurotrauma and the rule of rescue. Journal of Medical Ethics,
37, 707-710. doi: 10.1136/medethics-2011-100081
Honeybul, S., Gillett, G., Ho, K., & Lind, C. (2012). Ethical considerations for performing decompressive craniectomy as
a life-saving intervention for severe traumatic brain injury. Journal of Medical Ethics, 38(11), 657-661. doi: 10.1136/
medethics-2012-100672
Honeybul, S., Ho, K. M., Gillett, G. R., Lind, C. R., & O’Hanlon, S. (2012). Futility and neurotrauma: Can we make an objective
assessment? Medical Journal of Australia, 196(8), 531-533. doi: 10.5694/mja11.11485
Honeybul, S., Ho, K. M., Lind, C. R. P., & Gillett, G. R. (2011). Decompressive craniectomy for diffuse cerebral swelling
after trauma: Long-term outcome and ethical considerations. Journal of Trauma, 71(1), 128-132. doi: 10.1097/
TA.0b013e3182117b6c
Honeybul, S., Ho, K. M., Lind, C. R. P., & Gillett, G. R. (2011). Surgical intervention for severe head injury: Ethical
considerations when performing life-saving but non-restorative surgery. Acta Neurochirurgica, 153(5), 1105-1110. doi:
10.1007/s00701-011-0974-9
Honeybul, S., Ho, K. M., Lind, C. R. P., & Gillett, G. R. (2011). The future of decompressive craniectomy for diffuse traumatic
brain injury. Journal of Neurotrauma, 28(10), 2199-2200. doi: 10.1089/neu.2011.1907
Honeybul, S., O’Hanlon, S., Ho, K. M., & Gillett, G. (2011). The influence of objective prognostic information on the
likelihood of informed consent for decompressive craniectomy: A study of Australian anaesthetists. Anaesthesia &
Intensive Care, 39(4), 659-665.
Jones, D. G. (2011). Is multiple authorship in conceptual bioethics ethically sustainable? American Journal of Bioethics, 11(10),
30-32. doi: 10.1080/15265161.2011.603809
Jones, D. G. (2011). Academic leadership and departmental headship in turbulent times. Tertiary Education & Management,
17(4), 279-288. doi: 10.1080/13583883.2011.605906
Jones, D. G., & Whitaker, M. I. (2012). Anatomy’s use of unclaimed bodies: Reasons against continued dependence on an
ethically dubious practice. Clinical Anatomy, 25(2), 246-254. doi: 10.1002/ca.21223
Jones, D. G., & Whitaker, M. (2012). Reorienting bioethics by releasing it from any religious moorings. American Journal of
Bioethics, 12(12), 24-26. doi: 10.1080/15265161.2012.719269
King, M. R. (2012). A league of their own? Evaluating justifications for the division of sport into ‘enhanced’ and ‘unenhanced’
leagues. Sport, Ethics & Philosophy, 6(1), 31-45. doi: 10.1080/17511321.2011.587198
McMillan, J., & Gillett, G. (2011). A Husserlian account of mental distance and unconscious desire. Journal for Philosophy &
Psychiatry, (April). Retrieved from http://www.jfpp.org/80+M544f671c0ee.html.
Nie, J.-B. (2012). The fallacy and danger of dichotomizing cultural differences: The truth about medical truth telling in China.
Virtual Mentor, 14(4), 338-343.
Nie, J.-B. (2011). Non-medical sex-selective abortion in China: Ethical and public policy issues in the context of 40 million
missing females. British Medical Bulletin, 98(1), 7-20. doi: 10.1093/bmb/ldr015
Nie, L., Anderson, L., & Henaghan, M. (2012). Surrogacy and s 2(a)(ii): Interpreting the “medical condition” requirement in
ACART’s Guidelines on Surrogacy Arrangements involving Providers of Fertility Services (2007). New Zealand Family Law
Journal, (March), 130-134.
Pickering, N. (2011). Extending disorder: Essentialism, family resemblance and secondary sense. Medicine, Health Care &
Philosophy. Advance online publication. doi: 10.1007/s11019-011-9372-6
Pulvirenti, M., McMillan, J., & Lawn, S. (2012). Empowerment, patient centred care and self-management. Health
Expectations. Advance online publication. doi: 10.1111/j.1369-7625.2011.00757.x
Sopoaga, F., Connor, J. L., Dockerty, J. D., Adams, J., & Anderson, L. (2012). Training medical students in Pacific health
through an immersion programme in New Zealand. New Zealand Medical Journal, 125(1349). Retrieved from
http://journal.nzma.org.nz/journal/125-1349/5053/content.pdf.
Walsh, B., & Gillett, G. (2011). A post-structuralist view of evidence-based medicine (EBM): What EBM contributes to
philosophy. International Journal of Person Centered Medicine, 1(2), 223-231. doi: 10.5750/ijpcm.v1i2.62
Walsh, B., & Gillett, G. (2011). Is evidence-based medicine positivist? International Journal of Person Centered Medicine, 1(2),
232-239. doi: 10.5750/ijpcm.v1i2.63
Journal - Research Other
Anderson, L. (2012). Physiotherapists administering medications under instruction [Editorial]. British Journal of Sports
Medicine, 46(4), 222-223. doi: 10.1136/bjsm.2011.083782
Anderson, L. (2011). Bloodgate: Were the punishments fair? [Editorial]. British Journal of Sports Medicine, 45(12), 948-949.
doi: 10.1136/bjsm.2011.083881
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Anderson, L., & Bowyer, L. (2012). Sudden cardiac death screening: Notes of caution [Blog post]. British Journal of
Sports Medicine. Retrieved from http://blogs.bmj.com/bjsm/2012/05/31/sudden-cardiac-death-screening-notes-ofcaution/#disqus_thread.
Delany, C., & Anderson, L. (2012). Responding to the moral dimensions of physical therapy practice [Guest editorial]. Physical
Therapy Reviews, 17(3), 141-142.
Gillett, G. (2012). Foucault and current psychiatric practice [Commentary]. Philosophy, Psychiatry & Psychology, 19(1), 59-61.
doi: 10.1353/ppp.2012.0008
Gillett, G. (2012). [Review of the book Essays in the metaphysics of mind]. Philosophy, 87(1), 141-145. doi: 10.1017/
S0031819111000611
Harland, T., Pickering, N., & Anderson, L. (2012). Valuing teaching and teaching values. Journal of Primary Health Care, 4(4),
346-348.
Honeybul, S., Ho, K. M., Lind, C. R. P., & Gillett, G. R. (2011). Hypothermia in patients with brain injury: The way forward?
[Letter]. Lancet Neurology, 10(5), 405-406. doi: 10.1016/S1474-4422(11)70086-2
Hu, L.-Y., & Nie, J.-B. (2011). The fascination of medical ethics: Classic cases and controversies of different viewpoints
[Perspective]. Medicine & Philosophy, 32(10), 77-78.
Jones, D. G. (2012). Resurrecting unclaimed bodies [Letter to the editor]. Clinical Anatomy, 25(5), 674-675. doi: 10.1002/ca.22077
Jones, D. G. (2012). Adventures at the science-theology interface: Reflections on Am I my keeper’s brother?. Stimulus: The New
Zealand Journal of Christian Thought & Practice, 19(2), 26-32.
Jones, D. G. (2012). [Review of the book The Christian art of dying: Learning from Jesus]. Theological Book Review, 24(1), 64-65.
Jones, D. G. (2011). [Review of the book Possessing the Dead: The artful science of anatomy]. Clinical Anatomy, 24(4), 522-523.
doi: 10.1002/ca.21160
Jones, D. G., King, M. R., & Whitaker, M. I. (2012). Brains and persons: An educational perspective [Letter to the editor].
Clinical Anatomy, 25(4), 513-514. doi: 10.1002/ca.22029
Jones, D. G., & Whitaker, M. I. (2012). The contested realm of displaying dead bodies [Commentary]. Journal of Medical Ethics.
Advance online publication. doi: 10.1136/medethics-2012-100983
Nie, J.-B. (2012). To set a gross distortion straight: A reply to Reidar Lie’s book review of Jing-Bao Nie’s Medical ethics in
China: A transcultural interpretation (Routledge 2011) [Letter]. Asian Bioethics Review, 4(4), 399-406. doi: 10.1353/
asb.2012.0036
Journal - Professional & Other Non-Research Articles
Anderson, L. (2012). A new code of ethics: Reflecting professional concerns [Guest editorial]. New Zealand Journal of
Physiotherapy, 40(1), 1.
Anderson, L. (2011). Bloodgate reversal of fortune [Blog commentary]. British Journal of Sports Medicine. Retrieved from
http://bjsm.bmj.com/.
Anderson, L., & Walker, S. (2012). The New Zealand Bioethics Conference: No Country for Old Men (or Women): Increasing
Pressures on the Health Care System. HRC Ethics Notes, (March), 3.
Honeybul, S., Ho, K., Lind, C., & Gillett, G. (2011). [Reply to the letter to the editor, “Decompressive craniectomy for diffuse
cerebral swelling after trauma”]. Journal of Trauma, 71(1), 267. doi: 10.1097/TA.0b013e318222e167
Pickering, N., & Anderson, L. (2012). Recruitment of patients for research from among a clinician’s own patient group. HRC
Ethics Notes, (December), 1.
Other Research Output
Anderson. L. (2011). Aotearoa New Zealand Physiotherapy Code of Ethics and Professional Conduct with Commentary, 23p.
School of Dentistry
Office of the Dean
Journal - Research Article
Anderson, V. R., Pang, L. C., & Aarts, J. M. (2012). New Zealand dental technicians and continuing education: Findings from a
qualitative survey. New Zealand Dental Journal, 108(2), 47-54.
Anderson, V. R., Rich, A. M., & Seymour, G. J. (2011). Undergraduate dental education in New Zealand: 2007-2009 final-year
student feedback on clinical learning environments. New Zealand Dental Journal, 107(3), 85-90.
Benic, G. Z., Tawse-Smith, A., & Bennani, V. (2011). Clinical implications of nanosurface technology on clinical success and
survival rate of single implant restorations: A review. Revista Periodontia, 21(1), 55-64.
Benjamin, O., Silcock, P., Kieser, J. A., Waddell, J. N., Swain, M. V., & Everett, D. W. (2012). Development of a model mouth
containing an artificial tongue to measure the release of volatile compounds. Innovative Food Science & Emerging
Technologies, 15, 96-103. doi: 10.1016/j.ifset.2012.03.004
Bolter, C., Raniga, N., Waddell, J. N., & Kieser, J. (2012). Conservation of intraoral pressure changes during swallowing. Journal
of Dental Sciences. Advance online publication. doi: 10.1016/j.jds.2012.09.016
Bushby, S. K., Thomas, N., Priemel, P. A., Coulter, C. V., Rades, T., & Kieser, J. A. (2012). Determination of methylphenidate in
Calliphorid larvae by liquid-liquid extraction and liquid chromatography mass spectrometry: Forensic entomotoxicology
using an in vivo rat brain model. Journal of Pharmaceutical & Biomedical Analysis, 70, 456-461. doi: 10.1016/j.
jpba.2012.06.024
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Campbell, D. I., De Silva, R. K., De Silva, H., Sinon, S. H., & Rich, A. M. (2011). Temporomandibular joint synovial
chondromatosis with intracranial extension: A review and observations of patient observed for 4 years. Journal of Oral &
Maxillofacial Surgery, 69(8), 2247-2252. doi: 10.1016/j.joms.2010.10.042
Chang, Y.-S. M., Bennani, V., Tawse-Smith, A., & Girvan, L. (2011). Effect of a cordless retraction paste material on implant
surfaces: An in vitro study. Brazilian Oral Research, 25(6), 492-499. doi: 10.1590/S1806-83242011000600004
Cullinan, M. P., Palmer, J. E., Carle, A. D., West, M. J., & Seymour, G. J. (2012). Long term use of triclosan toothpaste and
thyroid function. Science of the Total Environment, 416, 75-79. doi: 10.1016/j.scitotenv.2011.11.063
Dann, T. J., Carr, D. J., Laing, R. M., Niven, B. E., & Kieser, J. (2012). Tearing of knicker fabrics. Forensic Science International,
217(1-3), 93-100. doi: 10.1016/j.forsciint.2011.10.029
Davidson, P. L., Taylor, M. C., Wilson, S. J., Walsh, K. A. J., & Kieser, J. A. (2012). Physical components of soft-tissue ballistic
wounding and their involvement in the generation of blood backspatter. Journal of Forensic Sciences. Advance online
publication. doi: 10.1111/j.1556-4029.2012.02143.x
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Antigen recognition and presentation in periapical tissues: A role
for TLR expressing cells? International Endodontic Journal, 44(2), 87-99. doi: 10.1111/j.1365-2591.2010.01817.x
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Toll-like receptor 2 expression in refractory periapical lesions.
International Endodontic Journal, 44(10), 907-916. doi: 10.1111/j.1365-2591.2011.01893.x
Friedlander, L., & Anderson, V. (2011). A new predoctoral endodontic module: Evaluating learning and effectiveness. Journal
of Dental Education, 75(3), 351-359.
Gregory, J., Thomson, W. M., Broughton, J. R., Cullinan, M. P., Seymour, G. J., Kieser, J. A., Donaghy, M.-A., Shearer, D.
M. (2012). Experiences and perceptions of oral health and oral health care among a sample of older New Zealanders.
Gerodontology, 29(1), 54-63. doi: 10.1111/j.1741-2358.2010.00402.x
Hsu, L., Power, D., Upritchard, J., Burton, J., Friedlander, R., Horswell, J., … Kieser, J., Tompkins, G. (2012). Amplification of
oral streptococcal DNA from human incisors and bite marks. Current Microbiology, 65(2), 207-211. doi: 10.1007/s00284012-0148-x
Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder
“tattoo,”: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and
electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4),
e6-e10. doi: 10.1016/j.tripleo.2011.03.049
Jack, H. C., Antoun, J. S., & Fowler, P. V. (2011). Evaluation of primary surgical outcomes in New Zealand patients with
unilateral clefts of the lip and palate. Australian Orthodontic Journal, 27(1), 23-27.
Kennedy, D. M., Stanton, J.-A. L., García, J. A., Mason, C., Rand, C. J., Kieser, J. A., & Tompkins, G. R. (2012). Microbial
analysis of bite marks by sequence comparison of streptococcal DNA. PLOS ONE, 7(12), e51757. doi: 10.1371/journal.
pone.0051757
Kieser, J. A., Tahere, J., Agnew, C., Kieser, D. C., Duncan, W., Swain, M. V., & Reeves, M. T. (2011). Morphoscopic analysis of
experimentally produced bony wounds from low-velocity ballistic impact. Forensic Science, Medicine, & Pathology, 7(4),
322-332. doi: 10.1007/s12024-011-9240-y
Leishman, S. J., Ford, P. J., Do, H. L., Palmer, J. E., Heng, N. C. K., West, M. J., Seymour, G. J., Cullinan, M. P. (2012).
Periodontal pathogen load and increased antibody response to heat shock protein 60 in patients with cardiovascular
disease. Journal of Clinical Periodontology, 39(10), 923-930. doi: 10.1111/j.1600-051X.2012.01934.x
Loch, C., Grando, L. J., Schwass, D. R., Kieser, J. A., Fordyce, R. E., & Simões-Lopes, P. C. (2012). Dental erosion in South
Atlantic dolphins (Cetacea: Delphinidae): A macro and microscopic approach. Marine Mammal Science. Advance online
publication. doi: 10.1111/j.1748-7692.2012.00562.x
McGettigan, A., Timmins, K., Herbison, P., Liversidge, H., & Kieser, J. (2011). Wisdom tooth formation as a method of
estimating age in a New Zealand population. Dental Anthropology, 24(2-3), 33-41.
Ng, L. K., Rich, A. M., Hussaini, H. M., Thomson, W. M., Fisher, A. L., Horne, L. S., & Seymour, G. J. (2011). Toll-like receptor
2 is present in the microenvironment of oral squamous cell carcinoma. British Journal of Cancer, 104(3), 460-463. doi:
10.1038/sj.bjc.6606057
Pang, L. C., Anderson, V. R., & Moffat, S. M. (2012). Initial University of Otago oral health graduates’ employment pathways
and preparedness for work. New Zealand Dental Journal, 108(3), 83-88.
Po, J. M. C., Kieser, J. A., Gallo, L. M., Tésenyi, A. J., Herbison, P., & Farella, M. (2011). Time-frequency analysis of chewing
activity in the natural environment. Journal of Dental Research, 90(10), 1206-1210. doi: 10.1177/0022034511416669
Rich, A. M., Ayers, K. M. S., Thomson, W. M., Sinclair, R. J., Rohan, M. J., & Seymour, G. J. (2012). Does performance in
selection processes predict performance as a dental student? European Journal of Dental Education, 16(1), 27-34. doi:
10.1111/j.1600-0579.2011.00706.x
Rose-Hill, S., Ford, P. J., Leishman, S. J., Do, H. L., Palmer, J. E., Heng, N. C. K., … Seymour, G. J., Cullinan, M. P. (2011).
Improved periodontal health and cardiovascular risk. Australian Dental Journal, 56(4), 352-357. doi: 10.1111/j.18347819.2011.01363.x
Siddiqi, A., Kieser, J. A., De Silva, R. K., McNaughton, A., & Duncan, W. J. (2012). Could the median-palate accommodate
wide-bodied implants in order to support maxillary over-dentures? A radiomorphometric study of human cadavers.
Clinical Oral Implants Research. Advance online publication. doi: 10.1111/clr.12050
Siddiqi, A., Payne, A. G. T., De Silva, R. K., & Duncan, W. J. (2011). Titanium allergy: Could it affect dental implant
integration? Clinical Oral Implants Research, 22(7), 673-680. doi: 10.1111/j.1600-0501.2010.02081.x
115
RESEARCH REPORT 2011/2012
Sinon, S. H., Rich, A. M., Hussaini, H. M., Yoon, H.-S., Firth, N. A., & Seymour, G. J. (2011). Metastases to the oral region from
pleural mesothelioma: Clinicopathologic review. Head & Neck. Advance online publication. doi: 10.1002/hed.21942
Soo, L., Leichter, J. W., Windle, J., Monteith, B., Williams, S. M., Seymour, G. J., & Cullinan, M. P. (2012). A comparison
of Er:YAG laser and mechanical debridement for the non-surgical treatment of chronic periodontitis: A randomized,
prospective clinical study. Journal of Clinical Periodontology, 39(6), 537-545. doi: 10.1111/j.1600-051X.2012.01873.x
Sosroseno, W., Bird, P. S., & Seymour, G. J. (2011). Nitric oxide production by a murine macrophage cell line (RAW264.7
cells) stimulated with Aggregatibacter actinomycetemcomitans surface–associated material. Anaerobe, 17(5), 246-251. doi:
10.1016/j.anaerobe.2011.06.006
Wang, Y. K., Nash, M. P., Pullan, A. J., Kieser, J. A., & Röhrle, O. (2012). Model-based identification of motion sensor placement
for tracking retraction and elongation of the tongue. Biomechanics & Modeling in Mechanobiology. Advance online
publication. doi: 10.1007/s10237-012-0407-6
Journal - Research Other
Kieser, J. (2012). [Review of the book Yuendumu: Legacy of a longitudinal growth study in Central Australia]. Annals of Human
Biology, 39(1), 88. doi: 10.3109/03014460.2011.628814
Journal - Professional & Other Non-Research Articles
Kieser, J. (2011). Social accountability and dental research [Guest editorial]. New Zealand Dental Journal, 107(3), 73.
School of Dentistry
Oral Diagnostic & Surgical Sciences
Journal - Research Article
Abdelghany, A., Nolan, A., & Freeman, R. (2011). Treating patients with dry mouth: General dental practitioners’ knowledge,
attitudes and clinical management. British Dental Journal, 211, E21. doi: 10.1038/sj.bdj.2011.966
Alsabeeha, N. H. M., Ma, S., & Atieh, M. A. (2012). Hydroxyapatite-coated oral implants: A systematic review and metaanalysis. International Journal of Oral & Maxillofacial Implants, 27(5), 1123-1130.
Alsabeeha, N. H. M., Payne, A. G. T., De Silva, R. K., & Thomson, W. M. (2011). Mandibular single-implant overdentures:
Preliminary results of a randomised-control trial on early loading with different implant diameters and attachment
systems. Clinical Oral Implants Research, 22(3), 330-337. doi: 10.1111/j.1600-0501.2010.02004.x
Anderson, V. R., Rich, A. M., & Seymour, G. J. (2011). Undergraduate dental education in New Zealand: 2007-2009 final-year
student feedback on clinical learning environments. New Zealand Dental Journal, 107(3), 85-90.
Atieh, M. A., Alsabeeha, N. H. M., Duncan, W. J., de Silva, R. K., Cullinan, M. P., Schwass, D., & Payne, A. G. T. (2012).
Immediate single implant restorations in mandibular molar extraction sockets: A controlled clinical trial. Clinical Oral
Implants Research. Advance online publication. doi: 10.1111/j.1600-0501.2011.02415.x
Atieh, M. A., Alsabeeha, N. H. M., Faggion, Jr., C. M., & Duncan, W. J. (2012). The frequency of peri-implant diseases: A
systematic review and meta-analysis. Journal of Periodontology. Advance online publication. doi: 10.1902/jop.2012.120592
Atieh, M. A., Alsabeeha, N. H., & Payne, A. G. (2012). Can resonance frequency analysis predict failure risk of immediately
loaded implants? International Journal of Prosthodontics, 25(4), 326-339.
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., de Silva, R. K., Schwass, D. R., & Duncan, W. J. (2012). The prognostic
accuracy of resonance frequency analysis in predicting failure risk of immediately restored implants. Clinical Oral Implants
Research. Advance online publication. doi: 10.1111/clr.12057
Atieh, M., & Shahmiri, R. A. (2011). The evaluation of optimal taper of immediately loaded wide-diameter implants: A finite
element analysis. Journal of Oral Implantology. Advance online publication. doi: 10.1563/AAID-JOI-D-11-00104
Becconsall-Ryan, K., & Love, R. M. (2011). Range and demographics of radiolucent jaw lesions in a new zealand population.
Journal of Medical Imaging & Radiation Oncology, 55(1), 43-51. doi: 10.1111/j.1754-9485.2010.02228.x
Broughton, J. R., Teh, M., Person, M., Randall, A., & Thomson, W. M. (2012). Self-reported oral health and dental service-use
of rangatahi within the rohe of Tainui. New Zealand Dental Journal, 108(3), 90-94.
Brown, S. D. K., & Payne, A. G. T. (2011). Immediately restored single implants in the aesthetic zone of the maxilla using a
novel design: 1-year report. Clinical Oral Implants Research, 22(4), 445-454. doi: 10.1111/j.1600-0501.2010.02125.x
Bryant, S., McLaughlin, K., Morgaine, K., & Drummond, B. (2011). Elite athletes and oral health. International Journal of
Sports Medicine, 32(9), 720-724. doi: 10.1055/s-0031-1277192
Campbell, D. I., De Silva, R. K., De Silva, H., Sinon, S. H., & Rich, A. M. (2011). Temporomandibular joint synovial
chondromatosis with intracranial extension: A review and observations of patient observed for 4 years. Journal of Oral &
Maxillofacial Surgery, 69(8), 2247-2252. doi: 10.1016/j.joms.2010.10.042
Cutfield, N. I., & Tong, D. C. (2012). Common medications among dental outpatients: Considerations in general dental
practice. New Zealand Dental Journal, 108(4), 140-147.
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Antigen recognition and presentation in periapical tissues: A role
for TLR expressing cells? International Endodontic Journal, 44(2), 87-99. doi: 10.1111/j.1365-2591.2010.01817.x
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Toll-like receptor 2 expression in refractory periapical lesions.
International Endodontic Journal, 44(10), 907-916. doi: 10.1111/j.1365-2591.2011.01893.x
Dias, D. K., De Silva, H. L., & Senadeera, W. M. (2011). Mid-maxillary distraction osteogenesis of cleft patients using a special
custom-made tooth-borne device. Ceylon Medical Journal, 56(3), 108-111.
116
RESEARCH REPORT 2011/2012
Goldsmith, S. M., De Silva, R. K., Tong, D. C., & Love, R. M. (2012). Influence of a pedicle flap design on acute postoperative
sequelae after lower third molar removal. International Journal of Oral & Maxillofacial Surgery, 41(3), 371-375. doi:
10.1016/j.ijom.2011.08.006
Hussaini, H. M., Angel, C. M., Speight, P. M., Firth, N. A., & Rich, A. M. (2012). A double-clear variant of epithelialmyoepithelial carcinoma of the parotid gland. Head & Neck Pathology, 6(4), 471-475. doi: 10.1007/s12105-012-0350-y
Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder
“tattoo,”: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and
electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4),
e6-e10. doi: 10.1016/j.tripleo.2011.03.049
Jattan, R., De Silva, H. L., De Silva, R. K., Rich, A. M., & Love, R. M. (2011). A case series of odontogenic keratocysts from a
New Zealand population over a 20-year period. New Zealand Dental Journal, 107(4), 112-116.
Kieser, J., Bolter, C., Raniga, N., Waddell, J. N., Swain, M., & Farland, G. (2011). Tongue-palate interactions during swallowing.
Journal of Texture Studies, 42(2), 95-102. doi: 10.1111/j.1745-4603.2010.00274.x
McCane, B., & Kean, M. R. (2011). Integration of parts in the facial skeleton and cervical vertebrae. American Journal of
Orthodontics & Dentofacial Orthopedics, 139(1), e13-e30. doi: 10.1016/j.ajodo.2010.06.016
McGettigan, A., Timmins, K., Herbison, P., Liversidge, H., & Kieser, J. (2011). Wisdom tooth formation as a method of
estimating age in a New Zealand population. Dental Anthropology, 24(2-3), 33-41.
Merrick, J., Chong, A., Parker, E., Roberts-Thomson, K., Misan, G., Spencer, J., Broughton, J., … Jamieson, L. (2012). Reducing
disease burden and health inequalities arising from chronic disease among Indigenous children: An early childhood caries
intervention [Study protocol]. BMC Public Health, 12, 323. doi: 10.1186/1471-2458-12-323
Ng, L. K., Rich, A. M., Hussaini, H. M., Thomson, W. M., Fisher, A. L., Horne, L. S., & Seymour, G. J. (2011). Toll-like receptor
2 is present in the microenvironment of oral squamous cell carcinoma. British Journal of Cancer, 104(3), 460-463. doi:
10.1038/sj.bjc.6606057
Nolan, A., Girdler, N. M., Seymour, R. A., & Thomason, J. M. (2012). The prevalence of dysplasia and malignant lip lesions in
transplant patients. Journal of Oral Pathology & Medicine, 41(2), 113-118. doi: 10.1111/j.1600-0714.2011.01072.x
Osman, R. B., Ma, S., Duncan, W., De Silva, R. K., Siddiqi, A., & Swain, M. V. (2012). Fractured zirconia implants and related
implant designs: Scanning electron microscopy analysis. Clinical Oral Implants Research. Advance online publication. doi:
10.1111/j.1600-0501.2011.02411.x
Parton, A. L., Tong, D. C., De Silva, H. L., Farella, M., & De Silva, R. K. (2011). A nine-year review of orthognathic surgery at
the University of Otago. New Zealand Dental Journal, 107(4), 117-120.
Patel, K. J., De Silva, H. L., Tong, D. C., & Love, R. M. (2011). Concordance between clinical and histopathologic diagnoses of
oral mucosal lesions. Journal of Oral & Maxillofacial Surgery, 69(1), 125-133. doi: 10.1016/j.joms.2010.07.075
Rich, A. M., Ayers, K. M. S., Thomson, W. M., Sinclair, R. J., Rohan, M. J., & Seymour, G. J. (2012). Does performance in
selection processes predict performance as a dental student? European Journal of Dental Education, 16(1), 27-34. doi:
10.1111/j.1600-0579.2011.00706.x
Siddiqi, A., Kieser, J. A., De Silva, R. K., McNaughton, A., & Duncan, W. J. (2012). Could the median-palate accommodate
wide-bodied implants in order to support maxillary over-dentures? A radiomorphometric study of human cadavers.
Clinical Oral Implants Research. Advance online publication. doi: 10.1111/clr.12050
Siddiqi, A., Payne, A. G. T., De Silva, R. K., & Duncan, W. J. (2011). Titanium allergy: Could it affect dental implant
integration? Clinical Oral Implants Research, 22(7), 673-680. doi: 10.1111/j.1600-0501.2010.02081.x
Sinon, S. H., Rich, A. M., Hussaini, H. M., Yoon, H.-S., Firth, N. A., & Seymour, G. J. (2011). Metastases to the oral region from
pleural mesothelioma: Clinicopathologic review. Head & Neck. Advance online publication. doi: 10.1002/hed.21942
Tong, D. C., Brooking, T. H., & Love, R. (2011). The management of maxillofacial trauma during the Korean War: A coming of
age of a specialty. Journal of Military & Veterans’ Health, 19(2), 10-14.
Tong, D. C., & Trottier, V. J. (2011). Interdisciplinary approach to the management of an 18-month-old burn victim in
Afghanistan. Military Medicine, 176(1), 115-118.
Verma, P., & Love, R. M. (2011). A Micro CT study of the mesiobuccal root canal morphology of the maxillary first molar
tooth. International Endodontic Journal, 44(3), 210-217. doi: 10.1111/j.1365-2591.2010.01800.x
Journal - Research Other
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., Duncan, W., & Esposito, M. (2012). Interventions for replacing missing
teeth: alveolar ridge preservation techniques for oral implant site development (Protocol). Cochrane Database of Systematic
Reviews, 11, CD010176. doi: 10.1002/14651858.CD010176
Friedlander, L., Chandler, N., & Love, R. (2011). Periapical healing following combined non-surgical and surgical retreatments
[Case report]. ENDO, 5(1), 27-34.
Nolan, A. (2012). [Review of the book Pharmacology and therapeutics for dentistry]. New Zealand Dental Journal, 108(3), 117.
Ting, S. R. Y. J., Quick, A. N., & Winters, J. C. (2011). The impacted maxillary canine: Revisiting the clinical guideline, with case
illustrations. New Zealand Dental Journal, 107(1), 19-23.
117
RESEARCH REPORT 2011/2012
School of Dentistry
Oral Rehabilitation
Chapter in Book - Research
Beumer III, J., Sung, E. C., Kagan, R., Lyons, K. M., Gulbransen, H. J., Venkatachalam, B., & Ghaem-Maghami, N. (2011).
Oral management of patients treated with radiation therapy and/or chemoradiation. In J. Beumer III, M. T. Marunick, &
S. J. Esposito (Eds.), Maxillofacial rehabilitation: Prosthodontic and surgical management of cancer-related, acquired, and
congenital defects of the head and neck (3rd ed.) (pp. 1-59). Chicago: Quintessence Books.
Journal - Research Article
Abduo, J., Bennani, V., Lyons, K., Waddell, N., & Swain, M. (2011). A novel in vitro approach to assess the fit of implant
frameworks. Clinical Oral Implants Research, 22(6), 658-663. doi: 10.1111/j.1600-0501.2010.02019.x
Abduo, J., & Lyons, K. (2012). Effect of vertical misfit on strain within screw-retained implant titanium and zirconia
frameworks. Journal of Prosthodontic Research, 56(2), 102-109. doi: 10.1016/j.jpor.2011.09.001
Abduo, J., & Lyons, K. (2012). Clinical considerations for increasing occlusal vertical dimension: A review. Australian Dental
Journal, 57(1), 2-10. doi: 10.1111/j.1834-7819.2011.01640.x
Abduo, J., Lyons, K., Bennani, V., Waddell, N., & Swain, M. (2011). Fit of screw-retained fixed implant frameworks fabricated
by different methods: A systematic review. International Journal of Prosthodontics, 24(3), 207-220.
Abduo, J., Lyons, K., Waddell, N., Bennani, V., & Swain, M. (2012). A comparison of fit of CNC-milled titanium and zirconia
frameworks to implants. Clinical Implant Dentistry & Related Research, 14(Suppl. 1), e20-e29. doi: 10.1111/j.17088208.2010.00334.x
Abduo, J., & Swain, M. (2012). Influence of vertical misfit of titanium and zirconia frameworks on peri-implant strain.
International Journal of Oral & Maxillofacial Implants, 27(3), 529-536.
Abduo, J., & Swain, M. (2011). Self-reparability of glass-ionomer cements: An in vitro investigation. European Journal of Oral
Sciences, 119(2), 187-191. doi: 10.1111/j.1600-0722.2011.00810.x
Al-Zubeidi, M. I., Alsabeeha, N. H. M., Thomson, W. M., & Payne, A. G. T. (2012). Patient satisfaction and dissatisfaction with
mandibular two-implant overdentures using different attachment systems: 5-year outcomes. Clinical Implant Dentistry &
Related Research, 14(5), 696-707. doi: 10.1111/j.1708-8208.2010.00306.x
Al-Zubeidi, M. I., Alsabeeha, N. H. M., Thomson, W. M., & Payne, A. G. T. (2012). Patient satisfaction with maxillary
3-implant overdentures using different attachment systems opposing mandibular 2-implant overdentures. Clinical Implant
Dentistry & Related Research, 14(Suppl. 1), e11-e19. doi: 10.1111/j.1708-8208.2010.00332.x
Allsobrook, O. F. L., Leichter, J., Holborow, D., & Swain, M. (2011). Descriptive study of the longevity of dental implant
surgery drills. Clinical Implant Dentistry & Related Research, 13(3), 244-254. doi: 10.1111/j.1708-8208.2009.00205.x
Alothmani, O. S., Friedlander, L. T., Monteith, B. D., & Chandler, N. P. (2012). Influence of clinical experience on the
radiographic determination of endodontic working length. International Endodontic Journal. Advance online publication.
doi: 10.1111/j.1365-2591.2012.02109.x
Alsabeeha, N. H. M. (2012). Elders with implant overdentures: A 22-year clinical report. Gerodontology, 29(3), 239-242. doi:
10.1111/j.1741-2358.2012.00628.x
Alsabeeha, N. H. M., Ma, S., & Atieh, M. A. (2012). Hydroxyapatite-coated oral implants: A systematic review and metaanalysis. International Journal of Oral & Maxillofacial Implants, 27(5), 1123-1130.
Alsabeeha, N. H. M., Payne, A. G. T., De Silva, R. K., & Thomson, W. M. (2011). Mandibular single-implant overdentures:
Preliminary results of a randomised-control trial on early loading with different implant diameters and attachment
systems. Clinical Oral Implants Research, 22(3), 330-337. doi: 10.1111/j.1600-0501.2010.02004.x
Alsabeeha, N. H. M., Swain, M. V., & Payne, A. G. T. (2011). Clinical performance and material properties of single-implant
overdenture attachment systems. International Journal of Prosthodontics, 24(3), 247-254.
Anderson, V., Kang, M., & Foster Page, L. (2012). First-year oral health and dentistry student perceptions of future professional
work. European Journal of Dental Education, 16(1), e166-e173. doi: 10.1111/j.1600-0579.2011.00692.x
Anderson, V. R., Pang, L. C., & Aarts, J. M. (2012). New Zealand dental technicians and continuing education: Findings from a
qualitative survey. New Zealand Dental Journal, 108(2), 47-54.
Ang, S. F., Saadatmand, M., Swain, M. V., Klocke, A., & Schneider, G. A. (2012). Comparison of mechanical behaviors of
enamel rod and interrod regions in enamel. Journal of Materials Research, 27(2), 448-456. doi: 10.1557/jmr.2011.409
Angker, L., Swain, M. V., Wong, L., & Sissons, C. (2011). The effects of fluoride and mineralising treatments on plaque
microcosm Ca, P and F, pH responses and cariogenicity. New Zealand Dental Journal, 107(1), 12-18.
Areai, D. M., Thomson, W. M., Foster Page, L. A., Denny, S. J., Crengle, S., Clark, T. C., … Koopu, P. I. (2011). Self-reported
oral health, dental self-care and dental service use among New Zealand secondary school students: Findings from the
Youth 07 study. New Zealand Dental Journal, 107(4), 121-126.
Atieh, M. A., Alsabeeha, N. H. M., Duncan, W. J., de Silva, R. K., Cullinan, M. P., Schwass, D., & Payne, A. G. T. (2012).
Immediate single implant restorations in mandibular molar extraction sockets: A controlled clinical trial. Clinical Oral
Implants Research. Advance online publication. doi: 10.1111/j.1600-0501.2011.02415.x
Atieh, M. A., Alsabeeha, N. H., & Payne, A. G. (2012). Can resonance frequency analysis predict failure risk of immediately
loaded implants? International Journal of Prosthodontics, 25(4), 326-339.
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., de Silva, R. K., Schwass, D. R., & Duncan, W. J. (2012). The prognostic
accuracy of resonance frequency analysis in predicting failure risk of immediately restored implants. Clinical Oral Implants
Research. Advance online publication. doi: 10.1111/clr.12057
118
RESEARCH REPORT 2011/2012
Atieh, M., & Shahmiri, R. A. (2011). The evaluation of optimal taper of immediately loaded wide-diameter implants: A finite
element analysis. Journal of Oral Implantology. Advance online publication. doi: 10.1563/AAID-JOI-D-11-00104
Aziz, A., Chandler, N. P., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2012). Infection of
apical dentin and root-end cavity disinfection. Journal of Endodontics. Advance online publication. doi: 10.1016/j.
joen.2012.06.034
Bai, Y., Park, I. S., Lee, S. J., Bae, T. S., Duncan, W., Swain, M., & Lee, M. H. (2011). One-step approach for hydroxyapatiteincorporated TiO2 coating on titanium via a combined technique of micro-arc oxidation and electrophoretic deposition.
Applied Surface Science, 257(15), 7010-7018. doi: 10.1016/j.apsusc.2011.03.058
Bai, Y., Park, I. S., Park, H. H., Lee, M. H., Bae, T. S., Duncan, W., & Swain, M. (2011). The effect of annealing temperatures on
surface properties, hydroxyapatite growth and cell behaviors of TiO2 nanotubes. Surface & Interface Analysis, 43(6), 9981005. doi: 10.1002/sia.3683
Bechtle, S., Özcoban, H., Lilleodden, E. T., Huber, N., Schreyer, A., Swain, M. V., & Schneider, G. A. (2012). Hierarchical
flexural strength of enamel: Transition from brittle to damage-tolerant behaviour. Journal of the Royal Society Interface,
9(71), 1265-1274. doi: 10.1098/rsif.2011.0498
Bechtle, S., Özcoban, H., Yilmaz, E. D., Fett, T., Rizzi, G., Lilleodden, E. T., … Swain, M. V., Schneider, G. A. (2012). A method
to determine site-specific, anisotropic fracture toughness in biological materials. Scripta Materialia, 66(8), 515-518. doi:
10.1016/j.scriptamat.2011.12.027
Benic, G. Z., Tawse-Smith, A., & Bennani, V. (2011). Clinical implications of nanosurface technology on clinical success and
survival rate of single implant restorations: A review. Revista Periodontia, 21(1), 55-64.
Benjamin, O., Silcock, P., Kieser, J. A., Waddell, J. N., Swain, M. V., & Everett, D. W. (2012). Development of a model mouth
containing an artificial tongue to measure the release of volatile compounds. Innovative Food Science & Emerging
Technologies, 15, 96-103. doi: 10.1016/j.ifset.2012.03.004
Bennani, V., Aarts, J. M., & Hong He, L. (2012). A comparison of pressure generated by cordless gingival displacement
techniques. Journal of Prosthetic Dentistry, 107(6), 388-392.
Bogen, G., & Chandler, N. P. (2012). Pulp preservation in immature permanent teeth. Endodontic Topics, 23(1), 131-152. doi:
10.1111/j.1601-1546.2012.00286.x
Bolter, C., Raniga, N., Waddell, J. N., & Kieser, J. (2012). Conservation of intraoral pressure changes during swallowing. Journal
of Dental Sciences. Advance online publication. doi: 10.1016/j.jds.2012.09.016
Broadbent, J. M., Thomson, W. M., Boyens, J. V., & Poulton, R. (2011). Dental plaque and oral health during the first 32 years
of life. Journal of the American Dental Association, 142(4), 415-426.
Brown, S. D. K., & Payne, A. G. T. (2011). Immediately restored single implants in the aesthetic zone of the maxilla using a
novel design: 1-year report. Clinical Oral Implants Research, 22(4), 445-454. doi: 10.1111/j.1600-0501.2010.02125.x
Chang, Y.-S. M., Bennani, V., Tawse-Smith, A., & Girvan, L. (2011). Effect of a cordless retraction paste material on implant
surfaces: An in vitro study. Brazilian Oral Research, 25(6), 492-499. doi: 10.1590/S1806-83242011000600004
Chang, C. W., Waddell, J. N., Lyons, K. M., & Swain, M. V. (2011). Cracking of porcelain surfaces arising from abrasive
grinding with a dental air turbine. Journal of Prosthodontics, 20(8), 613-620. doi: 10.1111/j.1532-849X.2011.00760.x
Choi, J. E., Waddell, J. N., & Swain, M. V. (2011). Pressed ceramics onto zirconia: Part 2: Indentation fracture and influence of
cooling rate on residual stresses. Dental Materials, 27(11), 1111-1118. doi: 10.1016/j.dental.2011.08.003
Choi, J. H., Waddell, J. N., Torr, B., & Swain, M. V. (2011). Pressed ceramics onto zirconia. Part 1: Comparison of crystalline
phases present, adhesion to a zirconia system and flexural strength. Dental Materials, 27(12), 1204-1212. doi: 10.1126/
science.1159584
Cimilli, H., Aydemir, S., Arican, B., Mumcu, G., Chandler, N., & Kartal, N. (2012). Accuracy of the Dentaport ZX apex locator
for working length determination when retreating molar root canals. Australian Endodontic Journal. Advance online
publication. doi: 10.1111/aej.12010
Cimilli, H., Aydemir, S., Kartal, N., & Chandler, N. (2012). Comparing the accuracy of four electronic apex locators for
determining the minor diameter: An ex vivo study. Journal of Dental Sciences. Advance online publication. doi: 10.1016/j.
jds.2012.09.015
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Antigen recognition and presentation in periapical tissues: A role
for TLR expressing cells? International Endodontic Journal, 44(2), 87-99. doi: 10.1111/j.1365-2591.2010.01817.x
Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Toll-like receptor 2 expression in refractory periapical lesions.
International Endodontic Journal, 44(10), 907-916. doi: 10.1111/j.1365-2591.2011.01893.x
Egan, J. G., & Swindells, S. A. (2012). A novel prosthodontic alternative for patients who are edentulous and have microstomia:
A case report. Special Care in Dentistry, 32(4), 160-164. doi: 10.1111/j.1754-4505.2012.00256.x
Ellis, R., Bennani, V., Purton, D., Chandler, N., & Lowe, B. (2012). The effect of ultrasonic instruments on the quality
of preparation margins and bonding to dentin. Journal of Esthetic & Restorative Dentistry, 24(4), 278-285. doi:
10.1111/j.1708-8240.2011.00495.x
Foster Page, L. A., Kang, M., Anderson, V., & Thomson, W. M. (2012). Appraisal of the Dundee Ready Educational
Environment Measure in the New Zealand dental education environment. European Journal of Dental Education, 16(2),
78-85. doi: 10.1111/j.1600-0579.2011.00725.x
Foster Page, L. A., & Thomson, W. M. (2012). Caries prevalence, severity, and 3-year increment, and their impact upon
New Zealand adolescents’ oral-health-related quality of life. Journal of Public Health Dentistry, 72(4), 287-294. doi:
10.1111/j.1752-7325.2012.00336.x
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Foster Page, L. A., & Thomson, W. M. (2011). Dental caries in Taranaki adolescents: A cohort study. New Zealand Dental
Journal, 107(3), 91-96.
Foster Page, L. A., Thomson, W. M., Mohamed, A. R., & Traebert, J. (2011). Performance and cross-cultural comparison of
the short-form version of the CPQ11-14 in New Zealand, Brunei and Brazil. Health & Quality of Life Outcomes, 9, 40. doi:
10.1186/1477-7525-9-40
Foster Page, L. A., Thomson, W. M., & Quick, A. N. (2011). Changes in malocclusion over time in New Zealand adolescents.
Australian Orthodontic Journal, 27(2), 169-175.
Friedlander, L., & Anderson, V. (2011). A new predoctoral endodontic module: Evaluating learning and effectiveness. Journal
of Dental Education, 75(3), 351-359.
Friedlander, L. T., Chandler, N. P., & Drummond, B. K. (2012). Avulsion and replantation of a primary incisor tooth. Dental
Traumatology. Advance online publication. doi: 10.1111/j.1600-9657.2012.01168.x
He, L.-H., Foster Page, L., & Purton, D. (2012). An evaluation of dental operative simulation materials. Dental Materials
Journal, 31(4), 645-649. doi: 10.4012/dmj.2011-264
He, L.-H., & Jansen van Vuuren, L. (2012). Development of a dental model hardener. New Zealand Dental Journal, 108(1), 13-18.
He, L.-H., Purton, D., & Swain, M. (2011). A novel polymer infiltrated ceramic for dental simulation. Journal of Materials
Science: Materials in Medicine, 22(7), 1639-1643. doi: 10.1007/s10856-011-4350-3
He, L.-H., & Swain, M. (2011). A novel polymer infiltrated ceramic dental material. Dental Materials, 27(6), 527-534. doi:
10.1016/j.dental.2011.02.002
He, L.-H., Xu, Y., & Purton, D. G. (2011). In vitro demineralisation of the cervical region of human teeth. Archives of Oral
Biology, 56(5), 512-519. doi: 10.1016/j.archoralbio.2010.11.009
Horne, P., Bennani, V., Chandler, N., & Purton, D. (2012). Ultrasonic margin preparation for fixed prosthodontics: A pilot
study. Journal of Esthetic & Restorative Dentistry, 24(3), 201-209. doi: 10.1111/j.1708-8240.2011.00477.x
Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder
“tattoo,”: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and
electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4),
e6-e10. doi: 10.1016/j.tripleo.2011.03.049
Kardos, T. (2012). Cellular responses to metal ions released from implants. Journal of Oral Implantology. Advance online
publication. doi: 10.1563/aaid-joi-d-11-00249.1
Keng, F.-Y., Quick, A. N., Swain, M. V., & Herbison, P. (2012). A comparison of space closure rates between preactivated
nickel-titanium and titanium-molybdenum alloy T-loops: A randomized controlled clinical trial. European Journal of
Orthodontics, 34(1), 33-38. doi: 10.1093/ejo/cjq156
Kieser, J., Bolter, C., Raniga, N., Waddell, J. N., Swain, M., & Farland, G. (2011). Tongue-palate interactions during swallowing.
Journal of Texture Studies, 42(2), 95-102. doi: 10.1111/j.1745-4603.2010.00274.x
Kieser, J. A., He, L. H., Dean, M. C., Jones, M. E., Duncan, W. J., Swain, M. V., & Nelson, N. J. (2011). Structure and
compositional characteristics of caniniform dental enamel in the tuatara Sphenodon punctatus (Lepidosauria:
Rhynchocephalia). New Zealand Dental Journal, 107(2), 44-50.
Kieser, J. A., Tahere, J., Agnew, C., Kieser, D. C., Duncan, W., Swain, M. V., & Reeves, M. T. (2011). Morphoscopic analysis of
experimentally produced bony wounds from low-velocity ballistic impact. Forensic Science, Medicine, & Pathology, 7(4),
322-332. doi: 10.1007/s12024-011-9240-y
Kim, Y.-J. A., & Chandler, N. P. (2012). Determination of working length for teeth with wide or immature apices: A review.
International Endodontic Journal. Advance online publication. doi: 10.1111/iej.12032
Law, C., Bennani, V., Lyons, K., & Swain, M. (2012). Mandibular flexure and its significance on implant fixed prostheses: A
review. Journal of Prosthodontics, 21(3), 219-224. doi: 10.1111/j.1532-849X.2011.00798.x
Lee, A., He, L. H., Lyons, K., & Swain, M. V. (2012). Tooth wear and wear investigations in dentistry. Journal of Oral
Rehabilitation, 39(3), 217-225. doi: 10.1111/j.1365-2842.2011.02257.x
Loch, C., Grando, L. J., Schwass, D. R., Kieser, J. A., Fordyce, R. E., & Simões-Lopes, P. C. (2012). Dental erosion in South
Atlantic dolphins (Cetacea: Delphinidae): A macro and microscopic approach. Marine Mammal Science. Advance online
publication. doi: 10.1111/j.1748-7692.2012.00562.x
Mackie, A., Lyons, K., Thomson, W. M., & Payne, A. G. T. (2011). Mandibular two-implant overdentures: Three-year
prosthodontic maintenance using the locator attachment system. International Journal of Prosthodontics, 24(4), 328-331.
Mackie, A., Lyons, K., Thomson, W. M., & Payne, A. G. T. (2011). Mandibular two-implant overdentures: Prosthodontic
maintenance using different loading protocols and attachment systems. International Journal of Prosthodontics, 24(5), 405-416.
McGettigan, A., Timmins, K., Herbison, P., Liversidge, H., & Kieser, J. (2011). Wisdom tooth formation as a method of
estimating age in a New Zealand population. Dental Anthropology, 24(2-3), 33-41.
Osman, R. B., Ma, S., Duncan, W., De Silva, R. K., Siddiqi, A., & Swain, M. V. (2012). Fractured zirconia implants and related
implant designs: Scanning electron microscopy analysis. Clinical Oral Implants Research. Advance online publication. doi:
10.1111/j.1600-0501.2011.02411.x
Osman, R. B., Morgaine, K. C., Duncan, W., Swain, M. V., & Ma, S. (2012). Patients’ perspectives on zirconia and titanium
implants with a novel distribution supporting maxillary and mandibular overdentures: A qualitative study. Clinical Oral
Implants Research. Advance online publication. doi: 10.1111/clr.12106
Osman, R. B., Payne, A. G., & Ma, S. (2012). Prosthodontic maintenance of maxillary implant overdentures: A systematic
literature review. International Journal of Prosthodontics, 25(4), 381-391.
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Parmar, D., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2011). Bacterial localization and viability
assessment in human ex vivo dentinal tubules by fluorescence confocal laser scanning microscopy. International
Endodontic Journal, 44(7), 644-651. doi: 10.1111/j.1365-2591.2011.01867.x
Quick, A. N., Lim, Y., Loke, C., Juan, J., Swain, M., & Herbison, P. (2011). Moments generated by simple V-bends in nickel
titanium wires. European Journal of Orthodontics, 33(4), 457-460. doi: 10.1093/ejo/cjq103
Russell, A. A., Chandler, N. P., Hauman, C., Siddiqui, A. Y., & Tompkins, G. R. (2012). The butterfly effect: An investigation of
sectioned roots. Journal of Endodontics. Advance online publication. doi: 10.1016/j.joen.2012.09.016
Schwass, D. R., Leichter, J. W., Purton, D. G., & Swain, M. V. (2012). Evaluating the efficiency of caries removal using an
Er:YAG laser driven by fluorescence feedback control. Archives of Oral Biology. Advance online publication. doi: 10.1016/j.
archoralbio.2012.09.017
Siddiqi, A., Payne, A. G. T., De Silva, R. K., & Duncan, W. J. (2011). Titanium allergy: Could it affect dental implant
integration? Clinical Oral Implants Research, 22(7), 673-680. doi: 10.1111/j.1600-0501.2010.02081.x
Soo, L., Leichter, J. W., Windle, J., Monteith, B., Williams, S. M., Seymour, G. J., & Cullinan, M. P. (2012). A comparison
of Er:YAG laser and mechanical debridement for the non-surgical treatment of chronic periodontitis: A randomized,
prospective clinical study. Journal of Clinical Periodontology, 39(6), 537-545. doi: 10.1111/j.1600-051X.2012.01873.x
Thomson, W. M., Mejia, G. C., Broadbent, J. M., & Poulton, R. (2012). Construct validity of Locker’s global oral health item.
Journal of Dental Research, 91(11), 1038-1042. doi: 10.1177/0022034512460676
Traebert, J., de Lacerda, J. T., Foster Page, L. A., Thomson, W. M., & Bortoluzz, M. C. (2012). Impact of traumatic
dental injuries on the quality of life of schoolchildren. Dental Traumatology, 28(6), 423-428. doi: 10.1111/j.16009657.2012.01114.x
Violich, D. R., Purton, D. G., Chandler, N. P., & Monteith, B. D. (2012). Effect of the smear layer on a pulp proximityindicating instrument. Odontology, 100, 47-53. doi: 10.1007/s10266-011-0014-5
Zanicotti, D. G., Matsubara, F. B., Zielak, J. C., Giovanini, A. F., de Andrade Urban, C., & Deliberador, T. M. (2011). Nonprocessed adipose tissue graft in the treatment of peri-implant osseous defects in the rabbit’s tibiae: A pilot study. Journal
of Oral Implantology. Advance online publication. doi: 10.1563/aaid-joi-d-11-00149
Journal - Research Other
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., Duncan, W., & Esposito, M. (2012). Interventions for replacing missing
teeth: alveolar ridge preservation techniques for oral implant site development (Protocol). Cochrane Database of Systematic
Reviews, 11, CD010176. doi: 10.1002/14651858.CD010176
Bennani, V. (2012). [Review of the book Esthetics in implantology]. New Zealand Dental Journal, 108(1), 37.
Friedlander, L., Chandler, N., & Love, R. (2011). Periapical healing following combined non-surgical and surgical retreatments
[Case report]. ENDO, 5(1), 27-34.
Hanlin, S. M. (2012). [Review of the book Atlas of oral implantology]. New Zealand Dental Journal, 108(2), 76.
Hanlin, S. M. (2012). [Review of the book Flapless implantology]. New Zealand Dental Journal, 108(2), 76.
Law, C. (2012). [Review of the book Current concepts on temporomandibular disorders]. New Zealand Dental Journal, 108(1), 37.
Peché, W.-A., Jansen van Vuuren, L., & Park, C. (2011). Full-arched milled titanium implant bridge: Technical report. New
Zealand Dental Journal, 107(3), 101-103.
Journal - Professional & Other Non-Research Articles
Thomson, W. M., Caspi, A., Moffitt, T., & Broadbent, J. (2012). [Response to letter to the editor ‘Contamination’ by
personality]. European Journal of Oral Sciences, 120(5), 473. doi: 10.1111/j.1600-0722.2012.00996.x
School of Dentistry
Oral Sciences
Authored Book - Research
Nash, D. A., Friedman, J. W., Mathu-Muju, K. R., Robinson, P. G., Satur, J., Moffat, S., Kardos, R., … Fernando, E. (2012). A
review of the global literature on dental therapists: In the context of the movement to add dental therapists to the oral health
workforce in the United States. Battle Creek, MI: W. K. Kellogg Foundation, 456p.
Chapter in Book - Research
Monk, B. C., Niimi, K., Holmes, A. R., Strouse, J. J., Sklar, L. A., & Cannon, R. D. (2012). Fungal efflux-mediated resistance:
From targets to inhibitors. In G. Tegos & E. Mylonakis (Eds.), Antimicrobial drug discovery: Emerging strategies (pp. 77-88).
Oxford, UK: CABI.
Thomson, W. M., Ikebe, K., Tordoff, J. M., & Campbell, A. J. (2011). Dry mouth and medications. In M. I. MacEntee (Ed.),
Oral healthcare and the frail elderly: A clinical perspective (pp. 51-72). Ames, IA: Blackwell.
Tompkins, G. R. (2011). Genotypic comparison of bacterial DNA recovered from bitemarks and teeth. In R. B. J. Dorion (Ed.),
Bitemark evidence: A color atlas and text (2nd ed.). Boca Raton, FL: CRC Press.
Wade, K. J., & Meldrum, A. M. (2011). Gingivitis control. In F. S. Panagakos & R. M. Davies (Eds.), Gingival diseases: Their
aetiology, prevention and treatment (pp. 139-154). Rijeka, Croatia: InTech.
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Journal - Research Article
Al-Zubeidi, M. I., Alsabeeha, N. H. M., Thomson, W. M., & Payne, A. G. T. (2012). Patient satisfaction and dissatisfaction with
mandibular two-implant overdentures using different attachment systems: 5-year outcomes. Clinical Implant Dentistry &
Related Research, 14(5), 696-707. doi: 10.1111/j.1708-8208.2010.00306.x
Al-Zubeidi, M. I., Alsabeeha, N. H. M., Thomson, W. M., & Payne, A. G. T. (2012). Patient satisfaction with maxillary
3-implant overdentures using different attachment systems opposing mandibular 2-implant overdentures. Clinical Implant
Dentistry & Related Research, 14(Suppl. 1), e11-e19. doi: 10.1111/j.1708-8208.2010.00332.x
Aldawood, S., Ampuan, S. N. H., Medara, N., & Thomson, W. M. (2011). Orthodontic treatment provision and referral
preferences among New Zealand general dental practitioners. Australian Orthodontic Journal, 27(2), 145-154.
Allsobrook, O. F. L., Leichter, J., Holborow, D., & Swain, M. (2011). Descriptive study of the longevity of dental implant
surgery drills. Clinical Implant Dentistry & Related Research, 13(3), 244-254. doi: 10.1111/j.1708-8208.2009.00205.x
Alsabeeha, N. H. M., Payne, A. G. T., De Silva, R. K., & Thomson, W. M. (2011). Mandibular single-implant overdentures:
Preliminary results of a randomised-control trial on early loading with different implant diameters and attachment
systems. Clinical Oral Implants Research, 22(3), 330-337. doi: 10.1111/j.1600-0501.2010.02004.x
Anning, R. J., Thomson, W. M., & Quick, A. N. (2011). Orthodontic education programs: An international comparison
of students’ views and experiences. American Journal of Orthodontics & Dentofacial Orthopedics, 139(2), 220-227. doi:
10.1016/j.ajodo.2010.01.032
Areai, D. M., Thomson, W. M., Foster Page, L. A., Denny, S. J., Crengle, S., Clark, T. C., … Koopu, P. I. (2011). Self-reported
oral health, dental self-care and dental service use among New Zealand secondary school students: Findings from the
Youth 07 study. New Zealand Dental Journal, 107(4), 121-126.
Atieh, M. A., Alsabeeha, N. H. M., Duncan, W. J., de Silva, R. K., Cullinan, M. P., Schwass, D., & Payne, A. G. T. (2012).
Immediate single implant restorations in mandibular molar extraction sockets: A controlled clinical trial. Clinical Oral
Implants Research. Advance online publication. doi: 10.1111/j.1600-0501.2011.02415.x
Atieh, M. A., Alsabeeha, N. H. M., Faggion, Jr., C. M., & Duncan, W. J. (2012). The frequency of peri-implant diseases: A
systematic review and meta-analysis. Journal of Periodontology. Advance online publication. doi: 10.1902/jop.2012.120592
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., de Silva, R. K., Schwass, D. R., & Duncan, W. J. (2012). The prognostic
accuracy of resonance frequency analysis in predicting failure risk of immediately restored implants. Clinical Oral Implants
Research. Advance online publication. doi: 10.1111/clr.12057
Aziz, A., Chandler, N. P., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2012). Infection of
apical dentin and root-end cavity disinfection. Journal of Endodontics. Advance online publication. doi: 10.1016/j.
joen.2012.06.034
Bai, Y., Park, I. S., Lee, S. J., Bae, T. S., Duncan, W., Swain, M., & Lee, M. H. (2011). One-step approach for hydroxyapatiteincorporated TiO2 coating on titanium via a combined technique of micro-arc oxidation and electrophoretic deposition.
Applied Surface Science, 257(15), 7010-7018. doi: 10.1016/j.apsusc.2011.03.058
Bai, Y., Park, I. S., Park, H. H., Lee, M. H., Bae, T. S., Duncan, W., & Swain, M. (2011). The effect of annealing temperatures on
surface properties, hydroxyapatite growth and cell behaviors of TiO2 nanotubes. Surface & Interface Analysis, 43(6), 9981005. doi: 10.1002/sia.3683
Broadbent, J. M., Thomson, W. M., Boyens, J. V., & Poulton, R. (2011). Dental plaque and oral health during the first 32 years
of life. Journal of the American Dental Association, 142(4), 415-426.
Broughton, J. R., Teh, M., Person, M., Randall, A., & Thomson, W. M. (2012). Self-reported oral health and dental service-use
of rangatahi within the rohe of Tainui. New Zealand Dental Journal, 108(3), 90-94.
Bryant, S., McLaughlin, K., Morgaine, K., & Drummond, B. (2011). Elite athletes and oral health. International Journal of
Sports Medicine, 32(9), 720-724. doi: 10.1055/s-0031-1277192
Buxcey, A. J., Morgaine, K. C., Meldrum, A. M., & Cullinan, M. P. (2012). An exploratory study of the acceptability of
delivering oral health information in community pharmacies. New Zealand Dental Journal, 108(1), 19-24.
Chan, Y. M., Williams, S., Davidson, L. E., & Drummond, B. K. (2011). Orofacial and dental trauma of young children in
Dunedin, New Zealand. Dental Traumatology, 27(3), 199-202. doi: 10.1111/j.1600-9657.2011.00989.x
Cioffi, I., & Farella, M. (2011). Quality of randomised controlled trials in dentistry. International Dental Journal, 61(1), 37-42.
doi: 10.1111/j.1875-595X.2011.00007.x
Crocombe, L. A., Broadbent, J. M., Thomson, W. M., Brennan, D. S., & Poulton, R. (2012). Impact of dental visiting trajectory
patterns on clinical oral health and oral health-related quality of life. Journal of Public Health Dentistry, 72(1), 36-44. doi:
10.1111/j.1752-7325.2011.00281.x
Crocombe, L. A., Broadbent, J. M., Thomson, W. M., Brennan, D. S., Slade, G. D., & Poulton, R. (2011). Dental visiting
trajectory patterns and their antecedents. Journal of Public Health Dentistry, 71(1), 23-31. doi: 10.1111/j.17527325.2010.00196.x
Cullinan, M. P., Palmer, J. E., Carle, A. D., West, M. J., & Seymour, G. J. (2012). Long term use of triclosan toothpaste and
thyroid function. Science of the Total Environment, 416, 75-79. doi: 10.1016/j.scitotenv.2011.11.063
D’Mello, G., Chia, L., Hamilton, S. D., Thomson, W. M., & Drummond, B. K. (2011). Childhood obesity and dental caries
among paediatric dental clinic attenders. International Journal of Paediatric Dentistry, 21(3), 217-222. doi: 10.1111/j.1365263X.2011.01112.x
Doss, J. G., Thomson, W. M., Drummond, B. K., & Raja Latifah, R. J. (2011). Validity of the FACT-H&N (v 4.0) among
Malaysian oral cancer patients. Oral Oncology, 47(7), 648-652. doi: 10.1016/j.oraloncology.2011.04.023
122
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Espinoza, I., Thomson, W. M., Gamonal, J., & Arteaga, O. (2012). Disparities in aspects of oral-health-related quality of life
among Chilean adults. Community Dentistry & Oral Epidemiology. Advance online publication. doi: 10.1111/cdoe.12001
Faggion, Jr., C. M. (2012). Is the evidence supporting dental procedures strong? A survey of Cochrane systematic reviews in
oral health. Journal of Evidence-Based Dental Practice, 12(3), 131-134.e14. doi: 10.1016/j.jebdp.2012.05.003
Faggion, Jr., C. M. (2012). Guidelines for reporting pre-clinical in vitro studies on dental materials. Journal of Evidence-Based
Dental Practice, 12(4), 182-189. doi: 10.1016/j.jebdp.2012.10.001
Faggion, Jr., C. M., & Giannakopoulos, N. N. (2012). Quality of reporting in abstracts of randomized controlled trials
published in leading journals of periodontology and implant dentistry: A survey. Journal of Periodontology, 83(10), 12511256. doi: 10.1902/jop.2012.110609
Farella, M., De Oliveira, M. E., Gallo, L. M., Läubli, T., Tomatis, L., Müller, C., … Palla, S. (2011). Firing duration of masseter
motor units during prolonged low-level contractions. Clinical Neurophysiology, 122(12), 2433-2440. doi: 10.1016/j.
clinph.2011.05.017
Foster Page, L. A., Kang, M., Anderson, V., & Thomson, W. M. (2012). Appraisal of the Dundee Ready Educational
Environment Measure in the New Zealand dental education environment. European Journal of Dental Education, 16(2),
78-85. doi: 10.1111/j.1600-0579.2011.00725.x
Foster Page, L. A., & Thomson, W. M. (2012). Caries prevalence, severity, and 3-year increment, and their impact upon
New Zealand adolescents’ oral-health-related quality of life. Journal of Public Health Dentistry, 72(4), 287-294. doi:
10.1111/j.1752-7325.2012.00336.x
Foster Page, L. A., & Thomson, W. M. (2011). Dental caries in Taranaki adolescents: A cohort study. New Zealand Dental
Journal, 107(3), 91-96.
Foster Page, L. A., Thomson, W. M., Mohamed, A. R., & Traebert, J. (2011). Performance and cross-cultural comparison of
the short-form version of the CPQ11-14 in New Zealand, Brunei and Brazil. Health & Quality of Life Outcomes, 9, 40. doi:
10.1186/1477-7525-9-40
Foster Page, L. A., Thomson, W. M., & Quick, A. N. (2011). Changes in malocclusion over time in New Zealand adolescents.
Australian Orthodontic Journal, 27(2), 169-175.
Frese, S. A., Benson, A. K., Tannock, G. W., Loach, D. M., Kim, J., Zhang, M., … Heng, N. C. K., … Walter, J. (2011). The
evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri. PLoS Genetics, 7(2), e1001314. doi:
10.1371/journal.pgen.1001314
Friedlander, L. T., Chandler, N. P., & Drummond, B. K. (2012). Avulsion and replantation of a primary incisor tooth. Dental
Traumatology. Advance online publication. doi: 10.1111/j.1600-9657.2012.01168.x
Gaynor, W. N., & Thomson, W. M. (2012). Changes in young children’s OHRQoL after dental treatment under general
anaesthesia. International Journal of Paediatric Dentistry, 22(4), 258-264. doi: 10.1111/j.1365-263X.2011.01190.x
Gray, S., & West, L. M. (2012). Herbal medicines: A cautionary tale. New Zealand Dental Journal, 108(2), 68-72.
Gregory, J., Thomson, W. M., Broughton, J. R., Cullinan, M. P., Seymour, G. J., Kieser, J. A., Donaghy, M.-A., Shearer, D.
M. (2012). Experiences and perceptions of oral health and oral health care among a sample of older New Zealanders.
Gerodontology, 29(1), 54-63. doi: 10.1111/j.1741-2358.2010.00402.x
Haisman-Welsh, R. J., & Thomson, W. M. (2012). Changes in periodontitis prevalence over two decades in New Zealand:
Evidence from the 1988 and 2009 national surveys. New Zealand Dental Journal, 108(4), 134-138.
Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2012). The metabolic response of Candida albicans to farnesol under hyphaeinducing conditions. FEMS Yeast Research. Advance online publication. doi: 10.1111/j.1567-1364.2012.00837.x
Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2012). Metabolome analysis during the morphological transition of Candida
albicans. Metabolomics, 8(6), 1204-1217. doi: 10.1007/s11306-012-0416-6
Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2011). The metabolic basis of Candida albicans morphogenesis and quorum
sensing. Fungal Genetics & Biology, 48(8), 747-763. doi: 10.1016/j.fgb.2011.04.002
Hashim, R., Williams, S., & Thomson, W. M. (2012). Oral hygiene and dental caries in 5- to 6-year-old children in Ajman,
United Arab Emirates. International Journal of Dental Hygiene. Advance online publication. doi: 10.1111/idh.12011
Hashim, R., Williams, S., & Thomson, W. M. (2011). Severe early childhood caries and behavioural risk indicators among
young children in Ajman, United Arab Emirates. European Archives of Paediatric Dentistry, 12(4), 205-210.
Hayama, K., Ishibashi, H., Ishijima, S. A., Niimi, K., Tansho, S., Ono, Y., Monk, B. C., Holmes, A. R., … Cannon, R. D., Abe, S.
(2012). A D-octapeptide drug efflux pump inhibitor acts synergistically with azoles in a murine oral candidiasis infection
model. FEMS Microbiology Letters, 328(2), 130-137. doi: 10.1111/j.1574-6968.2011.02490.x
Heng, N. C. K., Haji-Ishak, N. S., Kalyan, A., Wong, A. Y. C., Lovrić, M., Bridson, J. M., Artamonova, J., Stanton, J.-A. L.,
Wescombe, P. A., Burton, J. P., Cullinan, M. P., Tagg, J. R. (2011). Genome sequence of the bacteriocin-producing oral
probiotic Streptococcus salivarius strain M18. Journal of Bacteriology, 193(22), 6402-6403. doi: 10.1128/jb.06001-11
Holmes, A. R., Chong, K., Rodrigues, E., Cannon, R. D., Carpenter, E., Ruske, D. R., & Dawes, P. J. D. (2012). Yeast colonization of
voice prostheses: Pilot study investigating effect of a bovine milk product containing anti-Candida albicans immunoglobulin
A antibodies on yeast colonization and valve leakage. Annals of Otology, Rhinology & Laryngology, 121(1), 61-66.
Holmes, A. R., Keniya, M. V., Ivnitski-Steele, I., Monk, B. C., Lamping, E., Sklar, L. A., & Cannon, R. D. (2011). The
monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump
activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates. Antimicrobial
Agents & Chemotherapy, 56(3), 1508-1515. doi: 10.1128/aac.05706-11
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Hsu, L., Power, D., Upritchard, J., Burton, J., Friedlander, R., Horswell, J., … Kieser, J., Tompkins, G. (2012). Amplification of
oral streptococcal DNA from human incisors and bite marks. Current Microbiology, 65(2), 207-211. doi: 10.1007/s00284012-0148-x
Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder
“tattoo,”: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and
electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4),
e6-e10. doi: 10.1016/j.tripleo.2011.03.049
Ishijima, S. A., Hayama, K., Takahashi, M., Holmes, A. R., Cannon, R. D., & Abe, S. (2012). N-acetylglucosamine
increases symptoms and fungal burden in a murine model of oral candidiasis. Medical Mycology, 50(3), 252-258. doi:
10.3109/13693786.2011.598194
Keng, F.-Y., Quick, A. N., Swain, M. V., & Herbison, P. (2012). A comparison of space closure rates between preactivated
nickel-titanium and titanium-molybdenum alloy T-loops: A randomized controlled clinical trial. European Journal of
Orthodontics, 34(1), 33-38. doi: 10.1093/ejo/cjq156
Kennedy, D. M., Stanton, J.-A. L., García, J. A., Mason, C., Rand, C. J., Kieser, J. A., & Tompkins, G. R. (2012). Microbial
analysis of bite marks by sequence comparison of streptococcal DNA. PLOS ONE, 7(12), e51757. doi: 10.1371/journal.
pone.0051757
Kieser, J., Bolter, C., Raniga, N., Waddell, J. N., Swain, M., & Farland, G. (2011). Tongue-palate interactions during swallowing.
Journal of Texture Studies, 42(2), 95-102. doi: 10.1111/j.1745-4603.2010.00274.x
Kieser, J. A., He, L. H., Dean, M. C., Jones, M. E., Duncan, W. J., Swain, M. V., & Nelson, N. J. (2011). Structure and
compositional characteristics of caniniform dental enamel in the tuatara Sphenodon punctatus (Lepidosauria:
Rhynchocephalia). New Zealand Dental Journal, 107(2), 44-50.
Kieser, J. A., Tahere, J., Agnew, C., Kieser, D. C., Duncan, W., Swain, M. V., & Reeves, M. T. (2011). Morphoscopic analysis of
experimentally produced bony wounds from low-velocity ballistic impact. Forensic Science, Medicine, & Pathology, 7(4),
322-332. doi: 10.1007/s12024-011-9240-y
Kim, I., Duncan, W. J., & Farella, M. (2012). Evaluation of mandibular growth using cone-beam computed tomography in a
rabbit model: A pilot study. New Zealand Dental Journal, 108(1), 9-12.
Leishman, S. J., Ford, P. J., Do, H. L., Palmer, J. E., Heng, N. C. K., West, M. J., Seymour, G. J., Cullinan, M. P. (2012).
Periodontal pathogen load and increased antibody response to heat shock protein 60 in patients with cardiovascular
disease. Journal of Clinical Periodontology, 39(10), 923-930. doi: 10.1111/j.1600-051X.2012.01934.x
Leonardi, R., Farella, M., & Cobourne, M. T. (2011). An association between sella turcica bridging and dental transposition.
European Journal of Orthodontics, 33(4), 461-465. doi: 10.1093/ejo/cjq106
Loch, C., Grando, L. J., Kieser, J. A., & Simões-Lopes, P. (2011). Dental pathology in dolphins (Cetacea: Delphinidae) from the
southern coast of Brazil. Diseases of Aquatic Organisms, 94(3), 225-234. doi: 10.3354/dao02339
Mackie, A., Lyons, K., Thomson, W. M., & Payne, A. G. T. (2011). Mandibular two-implant overdentures: Three-year
prosthodontic maintenance using the locator attachment system. International Journal of Prosthodontics, 24(4), 328-331.
Mackie, A., Lyons, K., Thomson, W. M., & Payne, A. G. T. (2011). Mandibular two-implant overdentures: Prosthodontic
maintenance using different loading protocols and attachment systems. International Journal of Prosthodontics, 24(5), 405-416.
Martina, R., Cioffi, I., Farella, M., Leone, P., Manzo, P., Matarese, G., … Cordasco, G. (2012). Transverse changes determined
by rapid and slow maxillary expansion: A low-dose CT-based randomized controlled trial. Orthodontics & Craniofacial
Research, 15(3), 159-168. doi: 10.1111/j.1601-6343.2012.01543.x
Matejka, K. M., Bremer, P. J., Tompkins, G. R., & Brooks, H. J. L. (2012). Antibiotic susceptibility of Moraxella catarrhalis
biofilms in a continuous flow model. Diagnostic Microbiology & Infectious Disease, 74, 394-398. doi: 10.1016/j.
diagmicrobio.2012.08.021
Matsubara, F. B., Zanicotti, D. G., Zielak, J. C., Giovanini, A. F., Gonzaga, C. C., de Andrade Urban, C., & Deliberador, T. M.
(2012). Nonprocessed adipose tissue graft in the treatment of dehiscence bone defects in rabbit tibiae: A pilot study.
Implant Dentistry, 21(3), 236-241. doi: 10.1097/ID.0b013e3182563e0d
Michelotti, A., Buonocore, G., Manzo, P., Pellegrino, G., & Farella, M. (2011). Dental occlusion and posture: An overview.
Progress in Orthodontics, 12(1), 53-58. doi: 10.1016/j.pio.2010.09.010
Michelotti, A., Cioffi, I., Landino, D., Galeone, C., & Farella, M. (2012). Effects of experimental occlusal interferences in
individuals reporting different levels of wake-time parafunctions. Journal of Orofacial Pain, 26(3), 168-175.
Michelotti, A., Iodice, G., Volaro, S., Steenks, M. H., & Farella, M. (2012). Evaluation of the short-term effectiveness of
education versus an occlusal splint for the treatment of myofascial pain of the jaw muscles. Journal of the American Dental
Association, 143(1), 47-53.
Moffat, S., & Coates, D. (2011). Attitudes of New Zealand dentists, dental specialists and dental students towards employing
dual-trained Oral Health graduates. British Dental Journal, 211, E16. doi: 10.1038/sj.bdj.2011.870
Moffat, S. M., & Coates, D. E. (2011). New Zealand’s oral health students: Education and workforce implications. New Zealand
Dental Journal, 107(2), 51-56.
Moffitt, T. E., Arseneault, L., Belsky, D., Dickson, N., Hancox, R. J., Harrington, H., … Poulton, R., … Thomson, W. M., Caspi,
A. (2011). A gradient of childhood self-control predicts health, wealth, and public safety. PNAS, 108(7), 2693-2698. doi:
10.1073/pnas.1010076108
Murray, C. M., Naysmith, K. E., Liu, G. C., & Drummond, B. K. (2012). A review of attention-deficit/hyperactivity disorder
from the dental perspective. New Zealand Dental Journal, 108(3), 95-101.
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Murray, C. J. L., Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., … Derrett, S., … Grainger, R., … Merriman, T.
R., … Taylor, W. J., … Thomson, W. M., … Lopez, A. D. (2012). Disability-adjusted life years (DALYs) for 291 diseases and
injuries in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859),
2197-2223. doi: 10.1016/S0140-6736(12)61689-4
Ng, L. K., Rich, A. M., Hussaini, H. M., Thomson, W. M., Fisher, A. L., Horne, L. S., & Seymour, G. J. (2011). Toll-like receptor
2 is present in the microenvironment of oral squamous cell carcinoma. British Journal of Cancer, 104(3), 460-463. doi:
10.1038/sj.bjc.6606057
Niimi, K., Harding, D. R. K., Holmes, A. R., Lamping, E., Niimi, M., Tyndall, J., Cannon, R. D., Monk, B. C. (2012). Specific
interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor.
Molecular Microbiology, 85(4), 747-767. doi: 10.1111/j.1365-2958.2012.08140.x
Niimi, K., Woods, M. A., Maki, K., Nakayama, H., Hatakenaka, K., Chibana, H., … Niimi, M., Cannon, R. D., Monk, B. C.
(2012). Reconstitution of high-level micafungin resistance detected in a clinical isolate of Candida glabrata identifies
functional homozygosity in glucan synthase gene expression. Journal of Antimicrobial Chemotherapy, 67(7), 1666-1676.
doi: 10.1093/jac/dks112
Osman, R. B., Ma, S., Duncan, W., De Silva, R. K., Siddiqi, A., & Swain, M. V. (2012). Fractured zirconia implants and related
implant designs: Scanning electron microscopy analysis. Clinical Oral Implants Research. Advance online publication. doi:
10.1111/j.1600-0501.2011.02411.x
Osman, R. B., Morgaine, K. C., Duncan, W., Swain, M. V., & Ma, S. (2012). Patients’ perspectives on zirconia and titanium
implants with a novel distribution supporting maxillary and mandibular overdentures: A qualitative study. Clinical Oral
Implants Research. Advance online publication. doi: 10.1111/clr.12106
Osman, R. B., Payne, A. G., & Ma, S. (2012). Prosthodontic maintenance of maxillary implant overdentures: A systematic
literature review. International Journal of Prosthodontics, 25(4), 381-391.
Pang, L. C., Anderson, V. R., & Moffat, S. M. (2012). Initial University of Otago oral health graduates’ employment pathways
and preparedness for work. New Zealand Dental Journal, 108(3), 83-88.
Parmar, D., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2011). Bacterial localization and viability
assessment in human ex vivo dentinal tubules by fluorescence confocal laser scanning microscopy. International
Endodontic Journal, 44(7), 644-651. doi: 10.1111/j.1365-2591.2011.01867.x
Parton, A. L., Tong, D. C., De Silva, H. L., Farella, M., & De Silva, R. K. (2011). A nine-year review of orthognathic surgery at
the University of Otago. New Zealand Dental Journal, 107(4), 117-120.
Peres, M. A., Peres, K. G., Thomson, W. M., Broadbent, J. M., Gigante, D. P., & Horta, B. L. (2011). The influence of family
income trajectories from birth to adulthood on adult oral health: Findings from the 1982 Pelotas birth cohort. American
Journal of Public Health, 101(4), 730-736. doi: 10.2105/AJPH.2009.184044
Peres, M. A., Thomson, W. M., Peres, K. G., Gigante, D. P., Horta, B. L., Broadbent, J. M., & Poulton, R. (2011). Challenges in
comparing the methods and findings of cohort studies of oral health: The Dunedin (New Zealand) and Pelotas (Brazil)
studies. Australian & New Zealand Journal of Public Health, 35(6), 549-556. doi: 10.1111/j.1753-6405.2011.00736.x
Po, J. M. C., Kieser, J. A., Gallo, L. M., Tésenyi, A. J., Herbison, P., & Farella, M. (2011). Time-frequency analysis of chewing
activity in the natural environment. Journal of Dental Research, 90(10), 1206-1210. doi: 10.1177/0022034511416669
Quick, A. N., Lim, Y., Loke, C., Juan, J., Swain, M., & Herbison, P. (2011). Moments generated by simple V-bends in nickel
titanium wires. European Journal of Orthodontics, 33(4), 457-460. doi: 10.1093/ejo/cjq103
Rich, A. M., Ayers, K. M. S., Thomson, W. M., Sinclair, R. J., Rohan, M. J., & Seymour, G. J. (2012). Does performance in
selection processes predict performance as a dental student? European Journal of Dental Education, 16(1), 27-34. doi:
10.1111/j.1600-0579.2011.00706.x
Rose-Hill, S., Ford, P. J., Leishman, S. J., Do, H. L., Palmer, J. E., Heng, N. C. K., … Seymour, G. J., Cullinan, M. P. (2011).
Improved periodontal health and cardiovascular risk. Australian Dental Journal, 56(4), 352-357. doi: 10.1111/j.18347819.2011.01363.x
Rothnie, J. J., Walsh, C. A., Wang, M. J.-J., Morgaine, K. C., & Drummond, B. K. (2012). An exploratory study of pregnant
women’s knowledge of child oral health care in New Zealand. New Zealand Dental Journal, 108(4), 129-133.
Russell, A. A., Chandler, N. P., Hauman, C., Siddiqui, A. Y., & Tompkins, G. R. (2012). The butterfly effect: An investigation of
sectioned roots. Journal of Endodontics. Advance online publication. doi: 10.1016/j.joen.2012.09.016
Saminathan, A., Vinoth, K. J., Wescott, D. C., Pinkerton, M. N., Milne, T. J., Cao, T., & Meikle, M. C. (2012). The effect of cyclic
mechanical strain on the expression of adhesion-related genes by periodontal ligament cells in two-dimensional culture.
Journal of Periodontal Research, 47(2), 212-221. doi: 10.1111/j.1600-0765.2011.01423.x
Schwass, D. R., Leichter, J. W., Purton, D. G., & Swain, M. V. (2012). Evaluating the efficiency of caries removal using an
Er:YAG laser driven by fluorescence feedback control. Archives of Oral Biology. Advance online publication. doi: 10.1016/j.
archoralbio.2012.09.017
Shearer, D. M., Thomson, W. M., Broadbent, J. M., & Poulton, R. (2011). Maternal oral health predicts their children’s caries
experience in adulthood. Journal of Dental Research, 90(5), 672-677. doi: 10.1177/0022034510393349
Shearer, D. M., Thomson, W. M., Broadbent, J. M., & Poulton, R. (2011). Does maternal oral health predict child oral healthrelated quality of life in adulthood? Health & Quality of Life Outcomes, 9, 50. doi: 10.1186/1477-7525-9-50
Shearer, D. M., Thomson, W. M., Caspi, A., Moffitt, T. E., Broadbent, J. M., & Poulton, R. (2012). Family history and oral
health: Findings from the Dunedin Study. Community Dentistry & Oral Epidemiology, 40(2), 105-115. doi: 10.1111/j.16000528.2011.00641.x
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Shearer, D. M., Thomson, W. M., Caspi, A., Moffitt, T. E., Broadbent, J. M., & Poulton, R. (2011). Inter-generational continuity
in periodontal health: Findings from the Dunedin Family History Study. Journal of Clinical Periodontology, 38(4), 301-309.
doi: 10.1111/j.1600-051X.2011.01704.x
Siddiqi, A., Kieser, J. A., De Silva, R. K., McNaughton, A., & Duncan, W. J. (2012). Could the median-palate accommodate
wide-bodied implants in order to support maxillary over-dentures? A radiomorphometric study of human cadavers.
Clinical Oral Implants Research. Advance online publication. doi: 10.1111/clr.12050
Siddiqi, A., Payne, A. G. T., De Silva, R. K., & Duncan, W. J. (2011). Titanium allergy: Could it affect dental implant
integration? Clinical Oral Implants Research, 22(7), 673-680. doi: 10.1111/j.1600-0501.2010.02081.x
Soma, K. J., Thomson, W. M., Morgaine, K. C., & Harding, W. J. (2012). A qualitative investigation of specialist orthodontists
in New Zealand. Part 1. Orthodontists and orthodontic practice. Australian Orthodontic Journal, 28(1), 2-16.
Soma, K. J., Thomson, W. M., Morgaine, K. C., & Harding, W. J. (2012). A qualitative investigation of specialist orthodontists
in New Zealand. Part 2. Orthodontists’ working lives and work-life balance. Australian Orthodontic Journal, 28(2), 170-180.
Soo, L., Leichter, J. W., Windle, J., Monteith, B., Williams, S. M., Seymour, G. J., & Cullinan, M. P. (2012). A comparison
of Er:YAG laser and mechanical debridement for the non-surgical treatment of chronic periodontitis: A randomized,
prospective clinical study. Journal of Clinical Periodontology, 39(6), 537-545. doi: 10.1111/j.1600-051X.2012.01873.x
Subramanian, J., Anderson, V. R., Morgaine, K. C., & Thomson, W. M. (2012). Improving the quality of educational strategies
in postgraduate dental education using student and graduate feedback: Findings from a qualitative study in New Zealand.
European Journal of Dental Education. Advance online publication. doi: 10.1111/eje.12006
Subramanian, J., Anderson, V. R., Morgaine, K. C., & Thomson, W. M. (2012). Effective and ineffective supervision in
postgraduate dental education: A qualitative study. European Journal of Dental Education. Advance online publication. doi:
10.1111/j.1600-0579.2012.00774.x
Subramanian, J., Anderson, V. R., Morgaine, K. C., & Thomson, W. M. (2012). The importance of ‘student voice’ in dental
education. European Journal of Dental Education. Advance online publication. doi: 10.1111/j.1600-0579.2012.00773.x
Tanabe, K., Lamping, E., Nagi, M., Okawada, A., Holmes, A. R., Miyazaki, Y., Cannon, R. D., Monk, B. C., Niimi, M. (2011).
Chimeras of Candida albicans Cdr1p and Cdr2p reveal features of pleiotropic drug resistance transporter structure and
function. Molecular Microbiology, 82(2), 416-433. doi: 10.1111/j.1365-2958.2011.07820.x
Thomson, W. M. (2012). Monitoring edentulism in older New Zealand adults over two decades: A review and commentary.
International Journal of Dentistry, 2012, 375407. doi: 10.1155/2012/375407
Thomson, W. M., Caspi, A., Poulton, R., Moffitt, T. E., & Broadbent, J. M. (2011). Personality and oral health. European Journal
of Oral Sciences, 119(5), 366-372. doi: 10.1111/j.1600-0722.2011.00840.x
Thomson, W. M., & Malden, P. E. (2011). Assessing change in the family impact of caries in young children after treatment
under general anaesthesia. Acta Odontologica Scandinavica, 69, 257-262. doi: 10.3109/00016357.2011.554862
Thomson, W. M., Mejia, G. C., Broadbent, J. M., & Poulton, R. (2012). Construct validity of Locker’s global oral health item.
Journal of Dental Research, 91(11), 1038-1042. doi: 10.1177/0022034512460676
Thomson, W. M., Sheiham, A., & Spencer, A. J. (2012). Sociobehavioral aspects of periodontal disease. Periodontology 2000,
60(1), 54-63. doi: 10.1111/j.1600-0757.2011.00405.x
Thomson, W. M., van der Putten, G.-J., de Baat, C., Ikebe, K., Matsuda, K.-i., Enoki, K., … Ling, G. Y. (2011). Shortening the
Xerostomia Inventory. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(3), 322-327. doi:
10.1016/j.tripleo.2011.03.024
Timmins, K., Liversidge, H., Farella, M., Herbison, P., & Kieser, J. (2012). The usefulness of dental and cervical maturation
stages in New Zealand children for Disaster Victim Identification. Forensic Science, Medicine, & Pathology, 8(2), 101-108.
doi: 10.1007/s12024-011-9251-8
Traebert, J., de Lacerda, J. T., Foster Page, L. A., Thomson, W. M., & Bortoluzz, M. C. (2012). Impact of traumatic
dental injuries on the quality of life of schoolchildren. Dental Traumatology, 28(6), 423-428. doi: 10.1111/j.16009657.2012.01114.x
Ukra, A., Bennani, F., & Farella, M. (2012). Psychological aspects of orthodontics in clinical practice: Part two: General
psychosocial wellbeing. Progress in Orthodontics, 13(1), 69-77. doi: 10.1016/j.p.2011.08.001
Ukra, A., Bennani, F., & Farella, M. (2011). Psychological aspects of orthodontics in clinical practice: Part One: Treatmentspecific variables. Progress in Orthodontics, 12(2), 143-148. doi: 10.1016/j.pio.2011.06.007
Vlok, J. L., Worthington, E. M., Hindson, J. A., Davidson, L. E., Thomson, W. M., & Drummond, B. K. (2011). Young people’s
perceptions of photographs of dental trauma. Dental Traumatology, 27(2), 109-112. doi: 10.1111/j.1600-9657.2010.00969.x
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., … Derrett, S., … Grainger, R., … Merriman, T.
R., … Taylor, W. J., … Thomson, W. M., … Murray, C. J. L. (2012). Years lived with disability (YLDs) for 1160 sequelae of
289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859),
2163-2196. doi: 10.1016/S0140-6736(12)61729-2
Weerasekera, M. M., Sissons, C. H., Wong, L., Anderson, S., Holmes, A. R., & Cannon, R. D. (2012). Use of denaturing gradient
gel electrophoresis (DGGE) for the identification of mixed oral yeasts in human saliva. Journal of Medical Microbiology.
Advance online publication. doi: 10.1099/jmm.0.050237-0
Wescombe, P. A., Hale, J. D. F., Heng, N. C. K., & Tagg, J. R. (2012). Developing oral probiotics from Streptococcus salivarius.
Future Microbiology, 7(12), 1355-1371. doi: 10.2217/fmb.12.113
Zembić, A., Johannesen, L. H., Schou, S., Malo, P., Reichert, T., Farella, M., & Hämmerle, C. H. F. (2012). Immediately restored
one-piece single-tooth implants with reduced diameter: One-year results of a multi-center study. Clinical Oral Implants
Research, 23(1), 49-54. doi: 10.1111/j.1600-0501.2011.02174.x
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Journal - Research Other
Atieh, M. A., Alsabeeha, N. H. M., Payne, A. G. T., Duncan, W., & Esposito, M. (2012). Interventions for replacing missing
teeth: alveolar ridge preservation techniques for oral implant site development (Protocol). Cochrane Database of Systematic
Reviews, 11, CD010176. doi: 10.1002/14651858.CD010176
Drummond, B. (2012). [Review of the book Paediatric laser dentistry: A user’s guide]. New Zealand Dental Journal, 108(4), 156.
Drummond, B. (2012). [Review of the book How the tooth mouse met the tooth fairy]. New Zealand Dental Journal, 108(4), 157.
Drummond, B. (2012). [Review of the book Revolutions in pediatric dentistry]. New Zealand Dental Journal, 108(2), 76.
Horton, S. J., Johnston, C. L., Hutchinson, C. M. W., Taylor, P. A., & Wade, K. J. (2011). Clinical working postures of Bachelor
of Oral Health students. New Zealand Dental Journal, 107(3), 74-78.
Jack, H., & Bennani, F. (2012). [Review of the book Biomechanics in orthodontics: Principles and practice]. New Zealand Dental
Journal, 108(1), 37.
Stacknik, S., & Bennani, F. (2012). [Review of the book Manual of wire bending techniques]. New Zealand Dental Journal,
108(4), 156.
Thomson, M. (2012). [Review of the book Grammar rules: Writing with military precision]. New Zealand Dental Journal,
108(1), 37-38.
Thomson, W. M. (2011). [Commentary on the article Treating patients with dry mouth: General dental practitioners’ knowledge,
attitudes and clinical management]. British Dental Journal, 211(10), 475. doi: 10.1038/sj.bdj.2011.986
Ting, S. R. Y. J., Quick, A. N., & Winters, J. C. (2011). The impacted maxillary canine: Revisiting the clinical guideline, with case
illustrations. New Zealand Dental Journal, 107(1), 19-23.
Journal - Professional & Other Non-Research Articles
Faggion, Jr., C. M. (2012). Conflict of interest policies should be better reported in dental journals. Journal of the Canadian
Dental Association, 78, c52.
Thomson, W. M., Caspi, A., Moffitt, T., & Broadbent, J. (2012). [Response to letter to the editor ‘Contamination’ by
personality]. European Journal of Oral Sciences, 120(5), 473. doi: 10.1111/j.1600-0722.2012.00996.x
Intellectual Property
Coates, D. E., Haines, S. R., & Suttie, J. M. (2011). Deer antler extract for promoting angiogenesis. (US 8,067,364).
Commissioned Report for External Body
Stuart, K., Gilmour, J., Broadbent, J., & Robson, B. (2011). Oranga Waha: Oral health research priorities for Mäori: A Literature
Review. Commissioned by Health Research Council and The Ministry of Health. Wellington, New Zealand: Te Röpü
Rangahau Hauora a Eru Pömare. 67p.
Awarded Doctoral Degree
Farah, R. A. (2011). The role of blood and serum proteins in the pathogenesis of molar-incisor hypomineralisation (DClinDent).
University of Otago, Dunedin, New Zealand. 160p.
Otago School of Medical Sciences
Anatomy
Authored Book - Research
Matisoo-Smith, E., & Horsburgh, K. A. (2012). DNA for archaeologists. Walnut Creek, CA: Left Coast Press, 233p.
Authored Book - Other
Aresti, N. A., Ramachandran, M., & Stringer, M. D. (2012). Anatomy vivas for the iMRCS. Cambridge University Press, 114p.
Edited Book - Research
Dennison, J., Oxnard, C., & Obendorf, P. (Eds.). (2011). Endemic cretinism. New York: Springer, 215p.
Dennison, J., Summerhayes, G. R., & Matisoo-Smith, L. (Eds.). (2011). St Matthias Group: Results of the expedition to the South
Seas: 1908-1910: Vol. 2 [Edited translation]. Seattle: Amazon, 230p.
Jones, T. L., Storey, A. A., Matisoo-Smith, E. A., & Ramírez-Aliaga, J. M. (Eds.). (2011). Polynesians in America: Pre-Columbian
contacts with the New World. Plymouth, UK: AltaMira Press.
Chapter in Book - Research
Beavan, N., Mays, S., Cook, G., & Ditchfield, P. (2011). Stable isotope analysis. In W. Rodwell & C. Atkins (Eds.), St Peter’s,
Barton-upon-Humber, Lincolnshire: A parish church and its community (Vol.1: History, archaeology and architecture) (pp.
762-767). Oxford, UK: Oxbow Books.
Bedford, S., Regenvanu, R., Spriggs, M., Buckley, H., & Valentin, F. (2011). Vanuatu. In N. Márquez-Grant & L. Fibiger (Eds.),
The Routledge handbook of archaeological human remains and legislation: An international guide to laws and practice in the
excavation and treatment of archaeological human remains (pp. 657-671). London: Routledge.
Dell’Albani, P., Pellitteri, R., Tricarichi, E. M., D’Antoni, S., Berretta, A., & Catania, M. V. (2011). Markers of stem cells in
gliomas. In M. A. Hayat (Ed.), Tumors of the central nervous system (Vol. 1): Gliomas: Glioblastoma (Part 1) (pp. 175-190).
Dordrecht, Holland: Springer. doi: 10.1007/978-94-007-0344-5_19
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Gold, E. (2012). Activin. In M. Schwab (Ed.), Encyclopedia of cancer (3rd ed.). Berlin, Germany: Springer. doi: 10.1007/
springerreference_307109
Halcrow, S. E., & Tayles, N. (2011). The bioarchaeological investigation of children and childhood. In S. C. Agarwal & B. A
Glencross (Eds.), Social bioarchaeology (pp. 333-360). Chichester, UK: Wiley-Blackwell.
Halcrow, S.E, & Tayles, N. (2011). Human diversity in mainland Southeast Asia: The contribution of bioarchaeology. In N. J.
Enfield (Ed.), Dynamics of human diversity: The case of mainland Southeast Asia (pp. 47-61). Canberra, Australia: Pacific
Linguistics.
Halcrow, S., Tayles, N., Pureepatpong, N., & Boonlop, K. (2011). Thailand. In N. Márquez-Grant & L. Fibiger (Eds.), The
Routledge handbook of archaeological human remains and legislation: An international guide to laws and practice in the
excavation and treatment of archaeological human remains (pp. 623-631). London: Routledge.
Jones, T. L., Clarke, A. C., Cordero, M.-A., Green, R. C., Irwin, G., Klar, K. A., Matisoo-Smith, E. A., … Weisler, M. I. (2011).
Summary and conclusions. In T. L. Jones, A. A. Storey, E. A. Matisoo-Smith, & J. M. Ramírez-Aliaga (Eds.), Polynesians in
America: Pre-Columbian contacts with the New World (pp. 263-276). Plymouth, UK: AltaMira Press.
Knapp, M., Stiller, M., & Meyer, M. (2012). Generating barcoded libraries for multiplex high-throughput sequencing. In B.
Shapiro & M. Hofreiter (Eds.), Ancient DNA: Methods and protocols: Methods in molecular biology (Vol. 840) (pp. 155-170).
New York: Humana Press. doi: 10.1007/978-1-61779-516-9_19
Matisoo-Smith, E. (2012). The great blue highway: Human migration in the Pacific. In M. H. Crawford & B. C. Campbell
(Eds.), Causes and consequences of human migration: An evolutionary perspective (pp. 388-416). Cambridge, UK:
Cambridge University Press.
Matisoo-Smith, E. A. (2011). Human biological evidence for Polynesian contacts with the Americas: Finding Maui on Mocha?
In T. L. Jones, A. A. Storey, E. A. Matisoo-Smith, & J. M. Ramírez-Aliaga (Eds.), Polynesians in America: Pre-Columbian
contacts with the New World (pp. 208-222). Plymouth, UK: AltaMira Press.
Matisoo-Smith, E., & Martin, K. (2011). Kororäreka Kiore and Russell rats: History according to Pompallier’s resident rodents.
In K. Martin & B. Mercer (Eds.), The French Place in the Bay of Islands: Essays from Pompallier’s printery (pp. 256-265).
Russell, New Zealand: Mätou Matauwhi.
Storey, A. A., Clarke, A. C., & Matisoo-Smith, E. A. (2011). Identifying contact with the Americas: A commensal-based
approach. In T. L. Jones, A. A. Storey, E. A. Matisoo-Smith, & J. M. Ramírez-Aliaga (Eds.), Polynesians in America: PreColumbian contacts with the New World (pp. 111-138). Plymouth, UK: AltaMira Press.
Storey, A. A., Quiróz, D., & Matisoo-Smith, E. A. (2011). A reappraisal of the evidence for Pre-Columbian introduction of
chickens to the Americas. In T. L. Jones, A. A. Storey, E. A. Matisoo-Smith, & J. M. Ramírez-Aliaga (Eds.), Polynesians in
America: Pre-Columbian contacts with the New World (pp. 139-170). Plymouth, UK: AltaMira Press.
Stringer, M. D. (2011). Clinical anatomy of the newborn. In P. Puri (Ed.), Newborn surgery (3rd ed.) (pp. 29-38). London, UK:
Hodder Arnold.
Sugarman, I., Stringer, M. D., & Smyth, A. G. (2012). Congenital defects and surgical problems. In J. M. Rennie (Ed.), Rennie
and Roberton’s textbook of neonatology (5th ed.) (pp. 724-754). Edinburgh, UK: Elsevier.
Tayles, N., & Halcrow, S. (2011). New Zealand/Aotearoa. In N. Márquez-Grant & L. Fibiger (Eds.), The Routledge handbook of
archaeological human remains and legislation: An international guide to laws and practice in the excavation and treatment of
archaeological human remains (pp. 647-655). London: Routledge.
Tayles, N., Halcrow, S., & Pureepatpong, N. (2012). Regional developments: Southeast Asia. In J. E. Buikstra & C. A. Roberts
(Eds.), The global history of paleopathology: Pioneers and prospects (pp. 528-540). Oxford University Press.
Journal - Research Article
Abdelkrim, J., Hunt, G. R., Gray, R. D., & Gemmell, N. J. (2012). Population genetic structure and colonisation history of the
tool-using New Caledonian crow. PLoS ONE, 7(5), e36608. doi: 10.1371/journal.pone.0036608
Adler, C. J., Haak, W., Donlon, D., Cooper, A., and the Genographic Consortium, including Clarke, A. C., & Matisoo-Smith, E.
A. (2011). Survival and recovery of DNA from ancient teeth and bones. Journal of Archaeological Science, 38(5), 956-964.
doi: 10.1016/j.jas.2010.11.010
Adler, E. S., Hollis, J. H., Clarke, I. J., Grattan, D. R., & Oldfield, B. J. (2012). Neurochemical characterization and sexual
dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat. Journal of
Neuroscience, 32(45), 15913-15921. doi: 10.1523/jneurosci.2591-12.2012
Aggarwal, M., Hyland, B. I., & Wickens, J. R. (2012). Neural control of dopamine neurotransmission: Implications for
reinforcement learning. European Journal of Neuroscience, 35(7), 1115-1123. doi: 10.1111/j.1460-9568.2012.08055.x
Anderson, G. M. (2011). Pituitary actions of RFamide peptides: A critique of the evidence. Open Neuroendocrinology Journal,
4, 51-63. doi: 10.2174/1876528901104010051
Ang, W. C., Doyle, T., & Stringer, M. D. (2012). Left-sided and duplicate inferior vena cava: A case series and review. Clinical
Anatomy. Advance online publication. doi: 10.1002/ca.22090
Aplin, K. P., Suzuki, H., Chinen, A. A., Chesser, R. T., ten Have, J., Donnellan, S. C., … Matisoo-Smith, E., … Cooper, A. (2011).
Multiple geographic origins of commensalism and complex dispersal history of Black Rats. PLoS ONE, 6(11), e26357. doi:
10.1371/journal.pone.0026357
Arumugam, A., Milosavljevic, S., Woodley, S., & Sole, G. (2012). Can application of a pelvic belt change injured hamstring
muscle activity? Medical Hypotheses, 78(2), 277-282. doi: 10.1016/j.mehy.2011.10.045
Arumugam, A., Milosavljevic, S., Woodley, S., & Sole, G. (2012). Evaluation of changes in pelvic belt tension during 2
weight-bearing functional tasks. Journal of Manipulative & Physiological Therapeutics, 35(5), 390-395. doi: 10.1016/j.
jmpt.2012.04.019
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Arumugam, A., Milosavljevic, S., Woodley, S., & Sole, G. (2012). Effects of external pelvic compression on form closure, force
closure, and neuromotor control of the lumbopelvic spine: A systematic review. Manual Therapy, 17(4), 275-284. doi:
10.1016/j.math.2012.01.010
Aziz, A., Chandler, N. P., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2012). Infection of
apical dentin and root-end cavity disinfection. Journal of Endodontics. Advance online publication. doi: 10.1016/j.
joen.2012.06.034
Balanovsky, O., Dibirova, K., Dybo, A., Mudrak, O., Frolova, S., Pocheshkhova, E., … and the Genographic Consortium,
including Clarke, A. C., Matisoo-Smith, E. A. (2011). Parallel evolution of genes and languages in the Caucasus region.
Molecular Biology & Evolution, 28(10), 2905-2920. doi: 10.1093/molbev/msr126
Barad, Z., Shevtsova, O., Arbuthnott, G. W., & Leitch, B. (2012). Selective loss of AMPA receptors at corticothalamic synapses
in the epileptic stargazer mouse. Neuroscience, 217, 19-31. doi: 10.1016/j.neuroscience.2012.05.011
Beavan, N., Halcrow, S., McFadgen, B., Hamilton, D., Buckley, B., Sokha, T., … Chhem, K. R. (2012). Radiocarbon dates from
jar and coffin burials of the Cardamom Mountains reveal a unique mortuary ritual in Cambodia’s late-to post-Angkor
period (15th-17th centuries AD). Radiocarbon, 54(1), 1-22.
Bedford, S., Buckley, H. R., Valentin, F., Tayles, N., & Longga, N. F. (2011). Lapita burials, a new Lapita cemetery and postLapita burials from Malakula, Northern Vanuatu, Southwest Pacific. Journal of Pacific Archaeology, 2(2), 26-48.
Bednark, J. G., Reynolds, J. N. J., Stafford, T., Redgrave, P., & Franz, E. A. (2011). Creating a movement heuristic for voluntary
action: Electrophysiological correlates of movement-outcome learning. Cortex. Advance online publication. doi: 10.1016/j.
cortex.2011.12.005
Benzler, J., Ganjam, G. K., Krüger, M., Pinkenburg, O., Kutschke, M., Stöhr, S., … Grattan, D. R., Tups, A. (2012).
Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism.
Biochemical Journal, 447(1), 175-184. doi: 10.1042/bj20120834
Bosch, C., Degos, B., Deniau, J.-M., & Venance, L. (2011). Subthalamic nucleus high-frequency stimulation generates a
concomitant synaptic excitation–inhibition in substantia nigra pars reticulata. Journal of Physiology, 589(17), 4189-4207.
doi: 10.1113/jphysiol.2011.211367
Bosch, C., Mailly, P., Degos, B., Deniau, J.-M., & Venance, L. (2012). Preservation of the hyperdirect pathway of basal ganglia in
a rodent brain slice. Neuroscience, 215, 31-41. doi: 10.1016/j.neuroscience.2012.04.033
Brockmann, H. J., & Johnson, S. L. (2011). A long-term study of spawning activity in a Florida Gulf coast population of
horseshoe crabs (Limulus polyphemus). Estuaries & Coasts, 34(5), 1049-1067. doi: 10.1007/s12237-011-9419-1
Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2011). Differential changes in responses of hypothalamic and brainstem
neuronal populations to prolactin during lactation in the mouse. Biology of Reproduction, 84(4), 826-836. doi: 10.1095/
biolreprod.110.089185
Brown, R. S. E., Piet, R., Herbison, A. E., & Grattan, D. R. (2012). Differential actions of prolactin on electrical activity and
intracellular signal transduction in hypothalamic neurons. Endocrinology, 153(5), 2375-2384. doi: 10.1210/en.2011-2005
Buckley, H. R. (2011). Epidemiology of gout: Perspectives from the past. Current Rheumatology Reviews, 7(2), 106-113. doi:
10.2174/157339711795305022
Bunn, S. J., Ait-Ali, D., & Eiden, L. E. (2012). Immune-neuroendocrine integration at the adrenal gland: Cytokine control of
the adrenomedullary transcriptome. Journal of Molecular Neuroscience, 48(2), 413-419. doi: 10.1007/s12031-012-9745-1
Buschiazzo, E., Beck, J. S., & Gemmell, N. J. (2011). Design and implementation of degenerate microsatellite primers for the
mammalian clade. PLoS ONE, 6(12), e29582. doi: 10.1371/journal.pone.0029582
Chang, Y.-S. M., Bennani, V., Tawse-Smith, A., & Girvan, L. (2011). Effect of a cordless retraction paste material on implant
surfaces: An in vitro study. Brazilian Oral Research, 25(6), 492-499. doi: 10.1590/S1806-83242011000600004
Chapple, C. M., Nicholson, H., Baxter, G. D., & Abbott, J. H. (2011). Patient characteristics that predict progression of knee
osteoarthritis: A systematic review of prognostic studies. Arthritis Care & Research, 63(8), 1115-1125. doi: 10.1002/
acr.20492
Chen, S., Wang, H., Fong, A. H. Y., & Zhang, M. (2012). Micro-CT visualization of the cricothyroid joint cavity in cadavers.
Laryngoscope, 122(3), 614-621. doi: 10.1002/lary.22504
Chen, S., Wang, H., & Zhang, M. (2011). Calcification of the thyroid, cricoid and articular cartilages. Anatomy Research, 33(3),
223-227.
Cheong, R. Y., Kwakowsky, A., Barad, Z., Porteous, R., Herbison, A. E., & Ábrahám, I. M. (2012). Estradiol acts directly and
indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons.
Endocrinology, 153(8), 3792-3803. doi: 10.1210/en.2012-1232
Chong, Y. H., Campbell, A. J., Farrand, S., & McLennan, I. S. (2012). Anti-Müllerian hormone level in older women: Detection
of granulosa cell tumor recurrence. International Journal of Gynecological Cancer, 22(9), 1497-1499. doi: 10.1097/
IGC.0b013e318270ac69
Clarkson, A. N. (2012). Perisynaptic GABA receptors: The overzealous protector. Advances in Pharmacological Sciences, 2012,
708428. doi: 10.1155/2012/708428
Clarkson, A. N., Talbot, C. L., Wang, P.-Y., MacLaughlin, D. T., Donahoe, P. K., & McLennan, I. S. (2011). Müllerian inhibiting
substance is anterogradely transported and does not attenuate avulsion-induced death of hypoglossal motor neurons.
Experimental Neurology, 231(2), 304-308. doi: 10.1016/j.expneurol.2010.12.019
Clements, K. M., Smith, L. M., Reynolds, J. N. J., Overton, P. G., Thomas, J. D., & Napper, R. M. (2012). Early postnatal ethanol
exposure: Glutamatergic excitotoxic cell death during acute withdrawal. Neurophysiology, 44(5), 376-386. doi: 10.1007/
s11062-012-9308-7
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Constantin, S., Jasoni, C., Romanò, N., Lee, K., & Herbison, A. E. (2012). Understanding calcium homeostasis in postnatal
gonadotropin-releasing hormone neurons using cell-specific Pericam transgenics. Cell Calcium, 51(3-4), 267-276. doi:
10.1016/j.ceca.2011.11.005
Cornwall, J. (2011). Are nursing students safe when choosing gluteal intramuscular injection locations? Australasian Medical
Journal, 4(6), 315-321. doi: 10.4066/AMJ.2011.764
Cornwall, J. (2011). The diverse utility of wet prosections and plastinated specimens in teaching gross anatomy in New
Zealand. Anatomical Sciences Education, 4(5), 269-274. doi: 10.1002/ase.245
Cornwall, J. (2011). Using a pictorial quiz to facilitate learning during nursing science lectures. Practice & Evidence of the
Scholarship of Teaching & Learning in Higher Education, 6(2), 135-154.
Cornwall, J., Perry, G., Louw, G., & Stringer, M. D. (2012). Who donates their body to science? An international, multicenter,
prospective study. Anatomical Sciences Education, 5(4), 208-216. doi: 10.1002/ase.1278
Cornwall, J., & Pollard, M. F. (2012). Evaluation of free i-applications for tertiary level gross anatomy education. Australasian
Medical Journal, 5(4), 239-242. doi: 10.4066/AMJ.2012.1249
Cornwall, J., Stringer, M. D., & Duxson, M. (2011). Functional morphology of the thoracolumbar transversospinal muscles.
Spine, 36(16), E1053-E1061. doi: 10.1097/BRS.0b013e3181f79629
Cox, K. J., Bentley, R. A., Tayles, N., Buckley, H. R., Macpherson, C. G., & Cooper, M. J. (2011). Intrinsic or extrinsic population
growth in Iron Age northeast Thailand? The evidence from isotopic analysis. Journal of Archaeological Science, 38(3), 665671. doi: 10.1016/j.jas.2010.10.018
Craythorn, R. G., Winnall, W. R., Lederman, F., Gold, E. J., O’Connor, A. E., de Kretser, D. M., … Girling, J. E. (2012).
Progesterone stimulates expression of follistatin splice variants Fst288 and Fst315 in the mouse uterus. Reproductive
BioMedicine Online, 24(3), 364-374. doi: 10.1016/j.rbmo.2011.12.004
Cui, X., Lu, Z., Kurosawa, A., Klemm, L., Bagshaw, A., Tsai, A. G., Gemmell, N., … Lieber, M. R. (2012). Both CpG methylation
and AID are required for the fragility of the human Bcl-2 major breakpoint region: Implications for the timing of the
breaks in the t(14;18). Molecular & Cellular Biology. Advance online publication. doi: 10.1128/MCB.01436-12
D’Antoni, S., Berretta, A., Seminara, G., Longone, P., Giuffrida-Stella, A. M., Battaglia, G., … Catania, M. V. (2011). A
prolonged pharmacological blockage of type-5 metabotropic glutamate receptors protects cultured spinal cord neurons
against excitotoxic death. Neurobiology of Disease, 42(3), 252-264. doi: 10.1016/j.nbd.2011.01.013
Davis, J. A., Stringer, M. D., & Woodley, S. J. (2012). New insights into the proximal tendons of adductor longus, adductor
brevis and gracilis. British Journal of Sports Medicine, 46(12), 871-876. doi: 10.1136/bjsports-2011-090044
Dejean, C., Arbuthnott, G., Wickens, J. R., Le Moine, C., Boraud, T., & Hyland, B. I. (2011). Power fluctuations in beta and
gamma frequencies in rat globus pallidus: Association with specific phases of slow oscillations and differential modulation
by dopamine D1 and D2 receptors. Journal of Neuroscience, 31(16), 6098-6107. doi: 10.1523/JNEUROSCI.3311-09.2011
Dennis, N. A., Houghton, L. A., Jones, G. T., van Rij, A. M., Morgan, K., & McLennan, I. S. (2012). The level of serum antiMüllerian hormone correlates with vitamin D status in men and women but not in boys. Journal of Clinical Endocrinology
& Metabolism, 97(7), 2450-2455. doi: 10.1210/jc.2012-1213
Dharmaratne, N., Glendining, K. A., Young, T. R., Tran, H., Sawatari, A., & Leamey, C. A. (2012). Ten-m3 is required for the
development of topography in the ipsilateral retinocollicular pathway. PLOS ONE, 7(9), e43083. doi: 10.1371/journal.
pone.0043083
Dias, G. J., Cook, R. B., & Mirhosseini, M. (2011). Influence of food consistency on growth and morphology of the mandibular
condyle. Clinical Anatomy, 24(5), 590-598. doi: 10.1002/ca.21122
Domett, K. M., & Buckley, H. R. (2012). Large lytic cranial lesions: A differential diagnosis from pre-Angkorian Cambodia.
International Journal of Osteoarchaeology, 22(6), 731-739. doi: 10.1002/oa.1234
Domett, K. M., Newton, J., O’Reilly, D. J. W., Tayles, N., Shewan, L., & Beavan, N. (2011). Cultural modification of the
dentition in prehistoric Cambodia. International Journal of Osteoarchaeology. Advance online publication. doi: 10.1002/
oa.1245
Domett, K. M., O’Reilly, D. J. W., & Buckley, H. R. (2011). Bioarchaeological evidence for conflict in Iron Age north-west
Cambodia. Antiquity, 85(328), 441-458.
Eckert, M. J., Guévremont, D., Williams, J. M., & Abraham, W. C. (2012). Rapid visual stimulation increases extrasynaptic
glutamate receptor expression but not visual-evoked potentials in the adult rat primary visual cortex. European Journal of
Neuroscience. Advance online publication. doi: 10.1111/ejn.12053
Evans, J. J., & Anderson, G. M. (2012). Balancing ovulation and anovulation: Integration of the reproductive and energy
balance axes by neuropeptides. Human Reproduction Update, 18(3), 313-332. doi: 10.1093/humupd/dms004
Ferrington, L., Miners, J. S., Palmer, L. E., Bond, S. M., Povey, J. E., Kelly, P. A. T., & et al (2011). Angiotensin II-inhibiting
drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer’s disease.
American Journal of Translational Research, 3(2), 197-208.
Flack, N. A. M. S., Meikle, G. R., Reddy, M., Nicholson, H. D., & Woodley, S. J. (2012). Hip abductor muscle volume in women
with lateral hip pain: A case-controlled study. Surgical & Radiologic Anatomy, 34(9), 847-855. doi: 10.1007/s00276-0120970-7
Flack, N. A. M. S., Nicholson, H. D., & Woodley, S. J. (2012). A review of the anatomy of the hip abductor muscles, gluteus
medius, gluteus minimus, and tensor fascia lata. Clinical Anatomy, 25(6), 697-708. doi: 10.1002/ca.22004
Fouquet, A., Noonan, B. P., Rodrigues, M. T., Pech, N., Gilles, A., & Gemmell, N. J. (2012). Multiple quaternary refugia in the
eastern Guiana Shield revealed by comparative phylogeography of 12 frog species. Systematic Biology, 61(3), 461-489. doi:
10.1093/sysbio/syr130
130
RESEARCH REPORT 2011/2012
Gold, E., Marino, F. E., Harrison, C., Makanji, Y., & Risbridger, G. (2012). Activin-βc reduces reproductive tumour progression
and abolishes cancer-associated cachexia in inhibin deficient mice. Journal of Pathology. Advance online publication. doi:
10.1002/path.4142
Gold, E., & Risbridger, G. (2012). Activins and activin antagonists in the prostate and prostate cancer. Molecular & Cellular
Endocrinology, 359, 107-112. doi: 10.1016/j.mce.2011.07.005
Goldberg, J. A., & Reynolds, J. N. J. (2011). Spontaneous firing and evoked pauses in the tonically active cholinergic
interneurons of the striatum [Review]. Neuroscience, 198, 27-43. doi: 10.1016/j.neuroscience.2011.08.067
Goldstien, S. J., Dupont, L., Viard, F., Hallas, P. J., Nishikawa, T., Schiel, D. R., Gemmell, N. J., Bishop, J. D. D. (2011). Global
phylogeography of the widely introduced North West Pacific Ascidian Styela clava. PLoS ONE, 6(2), e16755. doi: 10.1371/
journal.pone.0016755
Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes
and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi:
10.3109/08982104.2011.637502
Guidera, A. K., Dawes, P. J. D., & Stringer, M. D. (2012). Cervical fascia: A terminological pain in the neck. ANZ Journal of
Surgery, 82, 786-791. doi: 10.1111/j.1445-2197.2012.06231.x
Gulliver, L. S. M., & Hurst, P. R. (2012). Repeat estradiol exposure differentially regulates protein expression patterns for
estrogen receptor and E-cadherin in older mouse ovarian surface epithelium: Implications for replacement and adjuvant
hormone therapies? Steroids, 77(6), 674-685. doi: 10.1016/j.steroids.2012.02.015
Gulliver, L. S. M., & Hurst, P. R. (2011). Novel approaches to quantify estradiol-induced loss of ERβ1 protein in older mouse
ovarian surface epithelium: New tools to assess the role of ER protein subtypes in predisposing to ovarian epithelial
cancer? Hormones & Cancer, 2(4), 204-213. doi: 10.1007/s12672-011-0077-3
Gupta, N., Jing, Y., Collie, N. D., Zhang, H., & Liu, P. (2012). Ageing alters behavioural function and brain arginine metabolism
in male Sprague-Dawley rats. Neuroscience, 226, 178-196. doi: 10.1016/j.neuroscience.2012.09.013
Gupta, N., Zhang, H., & Liu, P. (2012). Chronic difluoromethylornithine treatment impairs spatial learning and memory in
rats. Pharmacology Biochemistry & Behavior, 100(3), 464-473. doi: 10.1016/j.pbb.2011.10.011
Haber, M., Platt, D. E., Badro, D. A., Xue, Y., El-Sibai, M., Bonab, M. A., … and the Genographic Consortium, including Clarke,
A. C., Matisoo-Smith, E. A. (2011). Influences of history, geography, and religion on genetic structure: The Maronites in
Lebanon. European Journal of Human Genetics, 19(3), 334-340. doi: 10.1038/ejhg.2010.177
Halcrow, S., Tayles, N., Inglis, R., & Higham, C. (2012). Newborn twins from prehistoric mainland Southeast Asia: Birth, death
and personhood. Antiquity, 86(333), 838-852.
Halcrow, S., Tayles, N., Pureepatpong, N., & Boonlop, K. (2011). Human remains from archaeological sites in Thailand:
Legislative and ethical issues (in Thai). Murang Boran Journal, 37(3), 143-148.
Harlow, G. E., Summerhayes, G. R., Davies, H. L., & Matisoo-Smith, L. (2012). A jade gouge from Emirau Island, Papua
New Guinea (Early Lapita context, 3300 BP): A unique jadeitite. European Journal of Mineralogy, 24(2), 391-399. doi:
10.1127/0935-1221/2012/0024-2175
Harris, N. J., & Tayles, N. (2012). Burial containers: A hidden aspect of mortuary practices: Archaeothanatology at Ban Non
Wat, Thailand. Journal of Anthropological Archaeology, 31(2), 227-239. doi: 10.1016/j.jaa.2012.01.001
Hayes, S., Buckley, H., Bradley, R., Milne, N., & Dennison, J. (2012). Approximating the face of ‘Aunty’: A question of likeness.
Journal of Archaeological Method & Theory, 19(2), 306-321. doi: 10.1007/s10816-011-9115-2
Heng, N. C. K., Haji-Ishak, N. S., Kalyan, A., Wong, A. Y. C., Lovrić, M., Bridson, J. M., Artamonova, J., Stanton, J.-A. L.,
Wescombe, P. A., Burton, J. P., Cullinan, M. P., Tagg, J. R. (2011). Genome sequence of the bacteriocin-producing oral
probiotic Streptococcus salivarius strain M18. Journal of Bacteriology, 193(22), 6402-6403. doi: 10.1128/jb.06001-11
Herman, E. K., Walker, G., van der Giezen, M., & Dacks, J. B. (2011). Multivesicular bodies in the enigmatic amoeboflagellate
Breviata anathema and the evolution of ESCRT 0. Journal of Cell Science, 124, 613-621. doi: 10.1242/jcs.078436
Horn, T., Robertson, B. C., Will, M., Eason, D. K., Elliott, G. P., & Gemmell, N. J. (2011). Inheritance of telomere length in a
bird. PLoS ONE, 6(2), e17199. doi: 10.1371/journal.pone.0017199
Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder
“tattoo,”: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and
electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4),
e6-e10. doi: 10.1016/j.tripleo.2011.03.049
Idrus, N. M., & Napper, R. M. A. (2012). Acute and long-term Purkinje cell loss following a single ethanol binge during the
early third trimester equivalent in the rat. Alcoholism, 36(8), 1365-1373. doi: 10.1111/j.1530-0277.2012.01743.x
Igelström, K. M., & Heyward, P. M. (2012). Inhibition of hippocampal excitability by citalopram. Epilepsia. Advance online
publication. doi: 10.1111/j.1528-1167.2012.03660.x
James, R., Searcy, J. L., Le Bihan, T., Martin, S. F., Gliddon, C. M., Povey, J., … Horsburgh, K. (2012). Proteomic analysis
of mitochondria in APOE transgenic mice and in response to an ischemic challenge. Journal of Cerebral Blood Flow &
Metabolism, 32, 164-176. doi: 10.1038/jcbfm.2011.120
Jasoni, C. L., & Campbell, S. R. S. (2011). Defining the cellular targets of IL6 in the fetal mouse brain. Journal of Developmental
Origins of Health & Disease, 2(Suppl. 1), S77. doi: 10.1017/S2040174411000481
Johnson, S. L., & Brockmann, H. J. (2012). Alternative reproductive tactics in female horseshoe crabs. Behavioral Ecology,
23(5), 999-1008. doi: 10.1093/beheco/ars063
131
RESEARCH REPORT 2011/2012
Johnson, S. L., & Gemmell, N. J. (2012). Are old males still good males and can females tell the difference?: Do hidden
advantages of mating with old males off-set costs related to fertility, or are we missing something else? BioEssays, 34(7),
609-619. doi: 10.1002/bies.201100157
Kalamorz, F., Keis, S., McMillan, D. G. G., Olsson, K., Stanton, J.-A., Stockwell, P., Black, M. A., … Cook, G. M. (2011). Draft
genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1. Journal of Bacteriology, 193(16),
4290-4291. doi: 10.1128/jb.05035-11
Kennedy, D. M., Stanton, J.-A. L., García, J. A., Mason, C., Rand, C. J., Kieser, J. A., & Tompkins, G. R. (2012). Microbial
analysis of bite marks by sequence comparison of streptococcal DNA. PLOS ONE, 7(12), e51757. doi: 10.1371/journal.
pone.0051757
Kerr, J. R., & Davis, L. S. (2011). Benzylpiperazine in New Zealand: Brief history and current implications. Journal of the Royal
Society of New Zealand, 41(1), 155-164. doi: 10.1080/03036758.2011.557036
King, C. L., Tayles, N., & Gordon, K. C. (2011). Re-examining the chemical evaluation of diagenesis in human bone apatite.
Journal of Archaeological Science, 38, 2222-2230. doi: 10.1016/j.jas.2011.03.023
Kirkland, N. T., Kolbeinsson, I., Woodfield, T., Dias, G. J., & Staiger, M. P. (2011). Synthesis and properties of topologically
ordered porous magnesium. Materials Science & Engineering: B, 176(20), 1666-1672. doi: 10.1016/j.mseb.2011.04.006
Kirkland, N. T., Waterman, J., Birbilis, N., Dias, G., Woodfield, T. B. F., Hartshorn, R. M., & Staiger, M. P. (2012). Bufferregulated biocorrosion of pure magnesium. Journal of Materials Science: Materials in Medicine, 23, 283-291. doi: 10.1007/
s10856-011-4517-y
Knapp, M. (2011). The next generation of genetic investigations into the Black Death. PNAS, 108(38), 15669-15670. doi:
10.1073/pnas.1112574108
Knapp, M., Clarke, A. C., Horsburgh, K. A., & Matisoo-Smith, E. A. (2012). Setting the stage-building and working in an
ancient DNA laboratory. Annals of Anatomy, 194(1), 3-6. doi: 10.1016/j.aanat.2011.03.008
Knapp, M., Horsburgh, K. A., Prost, S., Stanton, J.-A., Buckley, H. R., Walter, R. K., & Matisoo-Smith, E. A. (2012). Complete
mitochondrial DNA genome sequences from the first New Zealanders. PNAS. Advance online publication. doi: 10.1073/
pnas.1209896109
Knowles, P. J., Douglas, S. A., & Bunn, S. J. (2011). Nicotinic stimulation of catecholamine synthesis and tyrosine hydroxylase
phosphorylation in cervine adrenal medullary chromaffin cells. Journal of Neuroendocrinology, 23(3), 224-231. doi:
10.1111/j.1365-2826.2010.02100.x
Knox, L. T., Jing, Y., Fleete, M. S., Collie, N. D., Zhang, H., & Liu, P. (2011). Scopolamine impairs behavioural
function and arginine metabolism in the rat dentate gyrus. Neuropharmacology, 61(8), 1452-1462. doi: 10.1016/j.
neuropharm.2011.08.042
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2011). Development and characterisation of modified
poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics, 408(1-2),
20-26. doi: 10.1016/j.ijpharm.2011.01.037
Kokay, I. C., Petersen, S. L., & Grattan, D. R. (2011). Identification of prolactin-sensitive GABA and kisspeptin neurons in regions
of the rat hypothalamus involved in the control of fertility. Endocrinology, 152(2), 526-535. doi: 10.1210/en.2010-0668
Ladyman, S. R., Fieldwick, D. M., & Grattan, D. R. (2012). Suppression of leptin-induced hypothalamic JAK/STAT signaling
and feeding response during pregnancy in the mouse. Reproduction, 144(1), 83-90. doi: 10.1530/rep-12-0112
Ladyman, S. R., Sapsford, T. J., & Grattan, D. R. (2011). Loss of acute satiety response to cholecystokinin in pregnant rats.
Journal of Neuroendocrinology, 23(11), 1091-1098. doi: 10.1111/j.1365-2826.2011.02191.x
Laird, D. F., Mucalo, M. R., & Dias, G. J. (2012). Vacuum-assisted infiltration of chitosan or polycaprolactone as a structural
reinforcement for sintered cancellous bovine bone graft. Journal of Biomedical Materials Research Part A, 100A(10), 25812592. doi: 10.1002/jbm.a.34193
Larsen, C. M., & Grattan, D. R. (2012). Prolactin, neurogenesis, and maternal behaviors. Brain, Behavior, & Immunity, 26(2),
201-209. doi: 10.1016/j.bbi.2011.07.233
Leitch, B., Shevtsova, O., Reusck, K., Bergin, D. H., & Liu, P. (2011). Spatial learning-induced increase in agmatine levels at
hippocampal CA1 synapses. Synapse, 65(2), 146-153. doi: 10.1002/syn.20828
Li, Q., Li, N., Le Tissier, P., Grattan, D. R., & Kerman, K. (2012). Miniaturized electrochemical immunosensor for label-free
detection of growth hormone. Electroanalysis, 24(6), 1272-1276. doi: 10.1002/elan.201200074
Lippold, S., Knapp, M., Kuznetsova, T., Leonard, J. A., Benecke, N., Ludwig, A., … Hofreiter, M. (2011). Discovery of lost
diversity of paternal horse lineages using ancient DNA. Nature Communications, 2, 450-455. doi: 10.1038/ncomms1447
Liu, P., Jing, Y., Collie, N. D., Campbell, S. A., & Zhang, H. (2011). Pre-aggregated Aβ25-35 alters arginine metabolism in the rat
hippocampus and prefrontal cortex. Neuroscience, 193, 269-282. doi: 10.1016/j.neuroscience.2011.07.054
Low, V. F., Fiorini, Z., Fisher, L., & Jasoni, C. L. (2012). Netrin-1 stimulates developing GnRH neurons to extend neurites to the
median eminence in a calcium-dependent manner. PLOS ONE, 7(10), e46999. doi: 10.1371/journal.pone.0046999
Lundquist, D., Gemmell, N. J., & Würsig, B. (2012). Behavioural responses of dusky dolphin groups (Lagenorhynchus obscurus)
to tour vessels off Kaikoura, New Zealand. PLOS ONE, 7(7), e41969. doi: 10.1371/journal.pone.0041969
Ma, S., Baillie, L. J. M., & Stringer, M. D. (2012). Reappraising the surface anatomy of the pterion and its relationship to the
middle meningeal artery. Clinical Anatomy, 25(3), 330-339. doi: 10.1002/ca.21232
Martínez-Cruz, B., Ziegle, J., Sanz, P., Sotelo, G., Anglada, R., Plaza, S., … for the Genographic Consortium, including Clarke,
A. C., Matisoo-Smith, E. A. (2011). Multiplex single-nucleotide polymorphism typing of the human Y chromosome using
TaqMan probes. Investigative Genetics, 2, 13. doi: 10.1186/2041-2223-2-13
132
RESEARCH REPORT 2011/2012
Martyn, H., Barrett, A., Trotman, P., & Nicholson, H. (2012). Medical students’ responses to the dissection of the heart and
brain: A dialogue on the seat of the soul. Clinical Anatomy, 25, 407-413. doi: 10.1002/ca.21219
Martyn, H., Pugazhenthi, K., Gould, M., Fink, J. W., McLeod, B., & Nicholson, H. D. (2011). Seasonal changes in morphology
and steroid receptor expression in the prostate of the brushtail possum (Trichosurus vulpecula): An animal model for the
study of prostate growth? Reproduction, Fertility & Development, 23(5), 702-713. doi: 10.1071/RD10158
Matisoo-Smith, E., & Daugherty, C. (2012). Africa to Aotearoa: The longest migration. Journal of the Royal Society of New
Zealand, 42(2), 87-92. doi: 10.1080/03036758.2012.673495
Mays, S., & Beavan, N. (2012). An investigation of diet in early Anglo-Saxon England using carbon and nitrogen stable isotope
analysis of human bone collagen. Journal of Archaeological Science, 39(4), 867-874. doi: 10.1016/j.jas.2011.10.013
McGrath, M. C. (2012). From distinct to indistinct, the life cycle of a medical heresy: Is osteopathic distinctiveness an
anachronism? International Journal of Osteopathic Medicine. Advance online publication. doi: 10.1016/j.ijosm.2012.08.004
McGrath, M. C., Jeffery, R., & Stringer, M. D. (2012). The dorsal sacral rami and branches: Sonographic visualisation of their
vascular signature. International Journal of Osteopathic Medicine, 15, 3-12. doi: 10.1016/j.ijosm.2011.09.002
McGrath, M. C., & Stringer, M. D. (2011). Bony landmarks in the sacral region: The posterior superior iliac spine and the
second dorsal sacral foramina: A potential guide for sonography. Surgical & Radiologic Anatomy, 33(3), 279-286. doi:
10.1007/s00276-010-0735-0
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2012). The orientation of the tympanic membrane [Letter to the editor].
Clinical Anatomy, 25(2), 260-262. doi: 10.1002/ca.22014
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2012). Surgical anatomy of the chorda tympani: A micro-CT study. Surgical
& Radiologic Anatomy, 34(6), 513-518.
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2011). Clinical anatomy of the chorda tympani: A systematic review. Journal
of Laryngology & Otology, 125(11), 1101-1108. doi: 10.1017/S0022215111001873
McManus, L. J., Stringer, M. D., & Dawes, P. J. D. (2012). Iatrogenic injury of the chorda tympani: A systematic review. Journal
of Laryngology & Otology, 126(1), 8-14. doi: 10.1017/S0022215111002039
Mirjalili, S. A., Hale, S. J. M., Buckenham, T., Wilson, B., & Stringer, M. D. (2012). A reappraisal of adult thoracic surface
anatomy. Clinical Anatomy, 25(7), 827-834. doi: 10.1002/ca.22091
Mirjalili, S. A., McFadden, S. L., Buckenham, T., & Stringer, M. D. (2012). A reappraisal of adult abdominal surface anatomy.
Clinical Anatomy, 25(7), 844-850. doi: 10.1002/ca.22119
Mirjalili, S. A., McFadden, S. L., Buckenham, T., & Stringer, M. D. (2012). Vertebral levels of key landmarks in the neck. Clinical
Anatomy, 25(7), 851-857. doi: 10.1002/ca.22124
Mirjalili, S. A., McFadden, S. L., Buckenham, T., Wilson, B., & Stringer, M. D. (2012). Anatomical planes: Are we teaching
accurate surface anatomy? Clinical Anatomy, 25(7), 819-826. doi: 10.1002/ca.22104
Mirjalili, S. A., Muirhead, J. C., & Stringer, M. D. (2012). Ultrasound visualization of the spinal accessory nerve in vivo. Journal
of Surgical Research, 175(1), e11-e16. doi: 10.1016/j.jss.2011.10.046
Mirjalili, S. A., & Stringer, M. D. (2011). The arterial supply of the major duodenal papilla and its relevance to endoscopic
sphincterotomy. Endoscopy, 43(4), 307-311. doi: 10.1055/s-0030-1256229
Mitchell, J. L., Carr, D. J., Niven, B. E., Harrison, K., & Girvan, E. (2012). Physical and mechanical degradation of shirting
fabrics in burial conditions. Forensic Science International. Advance online publication. doi: 10.1016/j.forsciint.2012.05.005
Mockett, B. G., Guévremont, D., Wutte, M., Hulme, S. R., Williams, J. M., & Abraham, W. C. (2011). Calcium/calmodulindependent protein kinase II mediates Group I metabotropic glutamate receptor-dependent protein synthesis and longterm depression in rat hippocampus. Journal of Neuroscience, 31(20), 7380-7391. doi: 10.1523/JNEUROSCI.6656-10.2011
Moore, A. E., & Stringer, M. D. (2011). Iatrogenic femoral nerve injury: A systematic review. Surgical & Radiologic Anatomy,
33(8), 649-658. doi: 10.1007/s00276-011-0791-0
Moore, A. E., Zhang, J., & Stringer, M. D. (2012). Iatrogenic nerve injury in a national no-fault compensation scheme:
An observational cohort study. International Journal of Clinical Practice, 66(4), 409-416. doi: 10.1111/j.17421241.2011.02869.x
Morgan, K., Dennis, N. A., Ruffman, T., Bilkey, D. K., & McLennan, I. S. (2011). The stature of boys is inversely correlated
to the levels of their Sertoli cell hormones: Do the testes restrain the maturation of boys? PLoS ONE, 6(6), e20533. doi:
10.1371/journal.pone.0020533
Morgan, K., Meredith, J., Kuo, J.-Y. A., Bilkey, D. K., & McLennan, I. S. (2011). The sex bias in novelty preference of
preadolescent mouse pups may require testicular Müllerian inhibiting substance. Behavioural Brain Research, 221(1), 304306. doi: 10.1016/j.bbr.2011.02.048
Napper, R., & Ross, S. (2012). An ethanol binge on postnatal days six plus eight results in a dose dependent behavioral change
in young rats. Alcoholism, 36(Suppl. 1), 276A. doi: 10.1111/j.1530-0277.2012.01803.x/pdf
Nguyen, T. L., Blanquet, A., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2012). On the role of surface roughness in the
corrosion of pure magnesium in vitro. Journal of Biomedical Materials Research Part B, 100 B(5), 1310-1318.
Nguyen, T. L., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2011). A novel manufacturing route for fabrication of
topologically-ordered porous magnesium scaffolds. Advanced Engineering Materials, 13(9), 872-881. doi: 10.1002/
adem.201100029
Nicol, S. C., Vanpé, C., Sprent, J., Morrow, G., & Anderson, N. A. (2011). Spatial ecology of a ubiquitous Australian
anteater, the short-beaked echidna (Tachyglossus aculeatus). Journal of Mammalogy, 92(1), 101-110. doi:
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Oorschot, D. (2012). The percentage of interneurons in the dorsal striatum of the rat, cat, monkey and human: A critique of
the evidence. Basal Ganglia. Advance online publication. doi: 10.1016/j.baga.2012.11.001
Oorschot, D. E. (2011). Indirect measures of neuroprotection are parameters to avoid: Examples from research on neonatal rat
hypoxia-ischemia. Image Analysis & Stereology, 30(1), 1-9. doi: 10.5566/ias.v30.p1-9
Osborne, A. J., Brauning, R., Schultz, J. K., Kennedy, M. A., Slate, J., & Gemmell, N. J. (2011). Development of a predicted
physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora. Molecular Ecology
Resources, 11(3), 503-513. doi: 10.1111/j.1755-0998.2010.02962.x
Ottley, E., & Gold, E. (2012). Insensitivity to the growth inhibitory effects of activin A: An acquired capability in prostate
cancer progression. Cytokine & Growth Factor Reviews, 23(3), 119-125. doi: 10.1016/j.cytogfr.2012.04.004
Overeem, K. A., & Kokkinidis, L. (2011). Nitric oxide synthesis in the basolateral complex of the amygdala is required for the
consolidation and expression of fear potentiated startle but not shock sensitization of the acoustic startle. Neurobiology of
Learning & Memory, 97(1), 97-104. doi: 10.1016/j.nlm.2011.10.001
Overman, J. J., Clarkson, A. N., Wanner, I. B., Overman, W. T., Eckstein, I., Maguire, J. L., … Carmichael, S. T. (2012). A role for
ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. PNAS, 109(33), E2230-E2239. doi:
10.1073/pnas.1204386109
Oxnard, C., Obendorf, P. J., Kefford, B. J., & Dennison, J. (2012). More on the Liang Bua finds and modern human cretins.
HOMO, 63(6), 407-412. doi: 10.1016/j.jchb.2012.09.005
Pankhurst, M. W., Bennett, W., Kirkcaldie, M. T. K., West, A. K., & Chung, R. S. (2011). Increased circulating leukocyte
numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in
metallothionein (MT) -l/ll null mutant mice. Journal of Neuroinflammation, 8, 172. doi: 10.1186/1742-2094-8-172
Pankhurst, M. W., Gell, D. A., Butler, C. W., Kirkcaldie, M. T. K., West, A. K., & Chung, R. S. (2012). Metallothionein (MT) -I
and MT-II expression are induced and cause zinc sequestration in the liver after brain injury. PLOS ONE, 7(2), e31185.
doi: 10.1371/journal.pone.0031185
Pankhurst, M. W., & McLennan, I. S. (2012). Inhibin B and anti-Müllerian hormone/Müllerian-inhibiting substance may
contribute to the male bias in autism. Translational Psychiatry, 2, e148. doi: 10.1038/tp.2012.72
Parmar, D., Hauman, C. H. J., Leichter, J. W., McNaughton, A., & Tompkins, G. R. (2011). Bacterial localization and viability
assessment in human ex vivo dentinal tubules by fluorescence confocal laser scanning microscopy. International
Endodontic Journal, 44(7), 644-651. doi: 10.1111/j.1365-2591.2011.01867.x
Peplow, P. V., & Baxter, G. D. (2012). Electroacupuncture for control of blood glucose in diabetes: Literature review. Journal of
Acupuncture & Meridian Studies, 5(1), 1-10. doi: 10.1016/j.jams.2011.11.018
Peplow, P. V., & Baxter, G. D. (2012). Gene expression and release of growth factors during delayed wound healing: A review
of studies in diabetic animals and possible combined laser phototherapy and growth factor treatment to enhance healing.
Photomedicine & Laser Surgery, 30(11), 617-636. doi: 10.1089/pho.2012.3312
Peplow, P. V., Chung, T.-Y., & Baxter, G. D. (2012). Laser photostimulation (660 nm) of wound healing in diabetic mice is not
brought about by ameliorating diabetes. Lasers in Surgery & Medicine, 44(1), 26-29. doi: 10.1002/lsm.21133
Peplow, P. V., Chung, T.-Y., & Baxter, G. D. (2012). Photodynamic modulation of wound healing: A review of human and
animal studies. Photomedicine & Laser Surgery, 30(3), 118-148. doi: 10.1089/pho.2011.3142
Peplow, P. V., Chung, T.-Y., & Baxter, G. D. (2011). Influence of two different fluences on laser photobiomodulation of wound
healing in diabetic and nondiabetic mice. AIP Conference Proceedings, 1364, 24-30. doi: 10.1063/1.3626908
Peplow, P. V., Chung, T.-Y., & Baxter, G. D. (2011). Laser photobiomodulation of wound healing: New findings with an
improved animal model. AIP Conference Proceedings, 1364, 167-171. doi: 10.1063/1.3626927
Peplow, P. V., Chung, T.-Y., Ryan, B., & Baxter, G. D. (2011). Laser photobiomodulation of gene expression and release of
growth factors and cytokines from cells in culture: A review of human and animal studies. Photomedicine & Laser Surgery,
29(5), 285-304. doi: 10.1089/pho.2010.2846
Peplow, P. V., Chung, T.-Y., Ryan, B., & Baxter, G. D. (2011). Laser photobiostimulation of wound healing: Reciprocity of
irradiance and exposure time on energy density for splinted wounds in diabetic mice. Lasers in Surgery & Medicine, 43(8),
843-850. doi: 10.1002/lsm.21094
Perkins, A., & Halcrow, S. E. (2012). Drumming up Asian awareness in Otago primary schools: Leading an educational performance
to connect children with their wider community. Journal of Educational Leadership, Policy & Practice, 27(1), 74-81.
Petrone, L., Easingwood, R., Barker, M. F., & McQuillan, A. J. (2011). In situ ATR-IR spectroscopic and electron microscopic
analyses of settlement secretions of Undaria pinnatifida kelp spores. Journal of the Royal Society Interface, 8(56), 410-422.
doi: 10.1098/rsif.2010.0316
Phillipps, H. R., & Hurst, P. R. (2012). XIAP: A potential determinant of ovarian follicular fate. Reproduction, 144, 165-176.
doi: 10.1530/rep-12-0142
Phillipps, H. R., Kokay, I. C., Grattan, D. R., & Hurst, P. R. (2011). X-linked inhibitor of apoptosis protein and active caspase-3
expression patterns in antral follicles in the sheep ovary. Reproduction, 142, 855-867. doi: 10.1530/rep-11-0177
Pietak, A. M. (2012). Structural evidence for electromagnetic resonance in plant morphogenesis. Biosystems. Advance online
publication. doi: 10.1016/j.biosystems.2012.01.009
Pietak, A. M. (2011). Endogenous electromagnetic fields in plant leaves: A new hypothesis for vascular pattern formation.
Electromagnetic Biology & Medicine, 30(2), 93-107. doi: 10.3109/15368378.2011.566779
Pinto, R., Carr, D., Helliker, M., Girvan, L., & Gridley, N. (2012). Degradation of military body armor due to wear: Laboratory
testing. Textile Research Journal, 82(11), 1157-1163. doi: 10.1177/0040517511435010
134
RESEARCH REPORT 2011/2012
Piwetz, S., Hung, S., Wang, J., Lundquist, D., & Würsig, B. (2012). Influence of vessel traffic on movements of indo-pacific
humpback dolphins (Sousa chinensis) off Lantau Island, Hong Kong. Aquatic Mammals, 38(3), 325-331. doi: 10.1578/
am.38.3.2012.325
Pollard, M. F., Thompson-Fawcett, M. W., & Stringer, M. D. (2012). The human ileocaecal junction: Anatomical evidence of a
sphincter. Surgical & Radiologic Anatomy, 34(1), 21-29. doi: 10.1007/s00276-011-0865-z
Quennell, J. H., Howell, C. S., Roa, J., Augustine, R. A., Grattan, D. R., & Anderson, G. M. (2011). Leptin deficiency and dietinduced obesity reduce hypothalamic kisspeptin expression in mice. Endocrinology, 152(4), 1541-1550. doi: 10.1210/
en.2010-1100
Redgrave, P., Vautrelle, N., & Reynolds, J. N. J. (2011). Functional properties of the basal ganglia’sre-entrant loop architecture:
Selection and reinforcement. Neuroscience, 198, 138-151. doi: 10.1016/j.neuroscience.2011.07.060
Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2011). Preparation of phytantriol
cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics &
Biopharmaceutics, 79(1), 15-22. doi: 10.1016/j.ejpb.2010.12.034
Rizwan, M. Z., Poling, M. C., Corr, M., Cornes, P. A., Augustine, R. A., Quennell, J. H., … Anderson, G. M. (2012). RFamiderelated peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action.
Endocrinology, 153(8), 3770-3779. doi: 10.1210/en.2012-1133
Robb, K. F., Buckley, H. R., Spriggs, M., & Bedford, S. (2012). Cortical index of three prehistoric human Pacific Island samples.
International Journal of Osteoarchaeology, 22(3), 284-293. doi: 10.1002/oa.1205
Rushaidhi, M., Collie, N. D., Zhang, H., & Liu, P. (2012). Agmatine selectively improves behavioural function in aged male
Sprague-Dawley rats. Neuroscience, 218(30), 206-215. doi: 10.1016/j.neuroscience.2012.05.015
Rushaidhi, M., Jing, Y., Kennard, J. T., Collie, N. D., Williams, J. M., Zhang, H., & Liu, P. (2012). Aging affects L-arginine and
its metabolites in memory-associated brain structures at the tissue and synaptoneurosome levels. Neuroscience, 209, 21-31.
doi: 10.1016/j.neuroscience.2012.02.021
Ryan, M. M., Mason-Parker, S. E., Tate, W. P., Abraham, W. C., & Williams, J. M. (2011). Rapidly induced gene networks
following induction of long-term potentiation at perforant path synapses in vivo. Hippocampus, 21(5), 541-553. doi:
10.1002/hipo.20770
Ryan, M. M., Ryan, B., Kyrke-Smith, M., Logan, B., Tate, W. P., Abraham, W. C., & Williams, J. M. (2012). Temporal profiling
of gene networks associated with the late phase of long-term potentiation in vivo. PLOS ONE, 7(7), e40538. doi: 10.1371/
journal.pone.0040538
Sakaguchi, S., Carr, D., Horsfall, I., & Girvan, L. (2012). Protecting the extremities of military personnel: Fragment
protective performance of one- and two-layer ensembles. Textile Research Journal, 82(12), 1295-1303. doi:
10.1177/0040517512436826
Samalia, L., & Stringer, M. D. (2012). A dissecting competition for medical students. Anatomical Sciences Education, 5, 109-113.
doi: 10.1002/ase.1256
Sapsford, T. J., Kokay, I. C., Östberg, L., Bridges, R. S., & Grattan, D. R. (2012). Differential sensitivity of specific neuronal
populations of the rat hypothalamus to prolactin action. Journal of Comparative Neurology, 520(5), 1062-1077. doi:
10.1002/cne.22775
Sasson, D. A., Johnson, S. L., & Brockmann, H. J. (2012). The role of age on sperm traits in the American horseshoe crab,
Limulus polyphemus. Animal Behaviour. Advance online publication. doi: 10.1016/j.anbehav.2012.07.023
Sawaya, S. M., Lennon, D., Buschiazzo, E., Gemmell, N., & Minin, V. N. (2012). Measuring microsatellite conservation in
mammalian evolution with a phylogenetic birth-death model. Genome Biology & Evolution, 4(6), 636-647. doi: 10.1093/
gbe/evs050
Schulz, J. M., Oswald, M. J., & Reynolds, J. N. J. (2011). Visual-induced excitation leads to firing pauses in striatal cholinergic
interneurons. Journal of Neuroscience, 31(31), 11133-11143. doi: 10.1523/JNEUROSCI.0661-11.2011
Schulz, J. M., Pitcher, T. L., Savanthrapadian, S., Wickens, J. R., Oswald, M. J., & Reynolds, J. N. J. (2011). Enhanced highfrequency membrane potential fluctuations control spike output in striatal fast-spiking interneurones in vivo. Journal of
Physiology, 589(17), 4365-4381. doi: 10.1113/jphysiol.2011.212944
Seo, S., Liu, P., & Leitch, B. (2011). Spatial learning-induced accumulation of agmatine and glutamate at hippocampal CA1
synaptic terminals. Neuroscience, 129, 28-36. doi: 10.1016/j.neuroscience.2011.07.007
Shadanbaz, S., & Dias, G. J. (2012). Calcium phosphate coatings on magnesium alloys for biomedical applications: A review.
Acta Biomaterialia, 8, 20-30. doi: 10.1016/j.actbio.2011.10.016
Shadanbaz, S., Walker, J., Staiger, M. P., Dias, G. J., & Pietak, A. (2012). Growth of calcium phosphates on magnesium
substrates for corrosion control in biomedical applications via immersion techniques. Journal of Biomedical Materials
Research Part B. Advance online publication. doi: 10.1002/jbm.b.32830
Shaw, B., Buckley, H., Summerhayes, G., Stirling, C., & Reid, M. (2011). Prehistoric migration at Nebira, South Coast of
Papua New Guinea: New insights into interaction using isotope and trace element concentration analyses. Journal of
Anthropological Archaeology, 30(3), 344-358. doi: 10.1016/j.jaa.2011.05.004
Shevtsova, O., & Leitch, B. (2011). Selective loss of AMPA receptor subunits at inhibitory neuron synapses in the cerebellum of
the ataxic stargazer mouse. Brain Research, 1427, 54-64. doi: 10.1016/j.brainres.2011.10.022
Siddiqi, A., Kieser, J. A., De Silva, R. K., McNaughton, A., & Duncan, W. J. (2012). Could the median-palate accommodate
wide-bodied implants in order to support maxillary over-dentures? A radiomorphometric study of human cadavers.
Clinical Oral Implants Research. Advance online publication. doi: 10.1111/clr.12050
135
RESEARCH REPORT 2011/2012
Sjoeholm, A., Bridges, R. S., Grattan, D. R., & Anderson, G. M. (2011). Region-, neuron-, and signaling pathway-specific
increases in prolactin responsiveness in reproductively experienced female rats. Endocrinology, 152(5), 1979-1988. doi:
10.1210/en.2010-1220
Sole, G., Milosavljevic, S., Nicholson, H., & Sullivan, S. J. (2012). Altered muscle activation following hamstring injuries.
British Journal of Sports Medicine, 46(2), 118-123. doi: 10.1136/bjsm.2010.079343
Sole, G., Milosavljevic, S., Nicholson, H., & Sullivan, S. J. (2011). Selective strength loss and decreased muscle activity in
hamstring injury. Journal of Orthopaedic & Sports Physical Therapy, 41(5), 354-363. doi: 10.2519/jospt.2011.3268
Stölting, K., Clarke, A. C., Meudt, H. M., Blankenhorn, W. U., & Wilson, A. B. (2011). Cost-effective fluorescent amplified
fragment length polymorphism (AFLP) analyses using a three primer system. Molecular Ecology Resources, 11(3), 494-502.
doi: 10.1111/j.1755-0998.2010.02957.x
Storey, A. A., Athens, J. S., Bryant, D., Carson, M., Emery, K., deFrance, S., Higham, C., … Matisoo-Smith, E. (2012).
Investigating the global dispersal of chickens in prehistory using ancient mitochondrial DNA signatures. PLOS ONE, 7(7),
e39171. doi: 10.1371/journal.pone.0039171
Storey, A. A., Quiroz, D., Beavan, N., & Matisoo-Smith, E. A. (2011). Pre-Columbian chickens of the Americas: A critical
review of the hypotheses and evidence for their origins. Rapa Nui Journal, 25(2), 5-19.
Storey, R. N., Stringer, M. D., & Woodley, S. J. (2012). Site of acute hamstring strains and activities associated with injury: A
systematic review. New Zealand Journal of Sports Medicine, 39(2), 36-42.
Stringer, M. D., Duncan, L. J., & Samalia, L. (2012). Using real-time ultrasound to teach living anatomy: An alternative
model for large classes. New Zealand Medical Journal, 125(1361). Retrieved from http://journal.nzma.org.nz/
journal/125-1361/5322/content.pdf.
Stringer, M. D., Fraser, S., Gordon, K. C., Sharples, K., & Windsor, J. A. (2012). Gallstones in New Zealand: Composition, risk
factors and ethnic differences. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/j.1445-2197.2012.06234.x
Stringer, M. D., Kano, M., Fausett, C., & Samalia, L. (2012). Unilateral short rectus femoris muscle belly. International Journal
of Anatomical Variations, 5, 56-58.
Stringer, M. D., Mirjalili, S. A., Meredith, S. J., & Muirhead, J. C. (2012). Redefining the surface anatomy of the parotid duct:
An in vivo ultrasound study. Plastic & Reconstructive Surgery, 130(5), 1032-1037. doi: 10.1097/PRS.0b013e318267d610
Stringer, M. D., Restieaux, M., Fisher, A. L., & Crosado, B. (2012). The vertebral venous plexuses: The internal veins are
muscular and external veins have valves. Clinical Anatomy, 25(5), 609-618. doi: 10.1002/ca.21281
Stringer, M. D., & Yassaie, S. (2011). Is the pelviureteric junction an anatomical entity? Journal of Pediatric Urology. Advance
online publication. doi: 10.1016/j.jpurol.2011.08.009
Taylor, D. R., Palmay, R., Cowan, J. O., & Herbison, G. P. (2011). Long term performance characteristics of an electrochemical
nitric oxide analyser. Respiratory Medicine, 105(2), 211-217. doi: 10.1016/j.rmed.2010.09.001
Valentin, F., Spriggs, M., Bedford, S., & Buckley, H. (2011). Vanuatu mortuary practices over three millennia: Lapita to the
early European contact period. Journal of Pacific Archaeology, 2(2), 1-17.
Walker, G., Dorrell, R. G., Schlacht, A., & Dacks, J. B. (2011). Eukaryotic systematics: A user’s guide for cell biologists and
parasitologists. Parasitology, 138(13), 1638-1663. doi: 10.1017/S0031182010001708
Walker, J., Shadanbaz, S., Kirkland, N. T., Stace, E., Woodfield, T., Staiger, M. P., & Dias, G. J. (2012). Magnesium alloys:
Predicting in vivo corrosion with in vitro immersion testing. Journal of Biomedical Materials Research Part B, 100B(4),
1134-1141. doi: 10.1002/jbm.b.32680
Wang, S., Deng, X., Han, H., Chang, J., Cao, X., & Zhang, M. (2011). Anatomical observation of the ‘holy plane’
for total mesorectal excision. Chinese Journal of Gastrointestinal Surgery, 14(1), 44-47. doi: 10.3760/cma.j.is
sn.1671-0274.2011.01.014
Waterman, J., Birbilis, N., Dias, G. J., Woodfield, T. B. F., & Staiger, M. P. (2012). Improving in vitro corrosion resistance of
biomimetic calcium phosphate coatings for Mg substrates using calcium hydroxide layer. Corrosion Engineering, Science &
Technology, 47(5), 340-345. doi: 10.1179/1743278212y.0000000018
Waterman, J., Pietak, A., Birbilis, N., Woodfield, T., Dias, G., & Staiger, M. P. (2011). Corrosion resistance of biomimetic
calcium phosphate coatings on magnesium due to varying pretreatment time. Materials Science & Engineering: B, 176(20),
1756-1760. doi: 10.1016/j.mseb.2011.06.021
Wickens, J. R., Hyland, B. I., & Tripp, G. (2011). Animal models to guide clinical drug development in ADHD: Lost in
translation? British Journal of Pharmacology, 164, 1107-1128. doi: 10.1111/j.1476-5381.2011.01412.x
Will, M., Hale, M. L., Schiel, D. R., & Gemmell, N. J. (2011). Low to moderate levels of genetic differentiation detected across the
distribution of the New Zealand abalone, Haliotis iris. Marine Biology, 158(6), 1417-1429. doi: 10.1007/s00227-011-1659-x
Wittmann, W., & McLennan, I. S. (2011). The male bias in the number of Purkinje cells and the size of the murine cerebellum
may require Müllerian inhibiting substance/anti-Müllerian hormone. Journal of Neuroendocrinology, 23, 831-838. doi:
10.1111/j.1365-2826.2011.02187.x
Wolff, J. N., & Gemmell, N. J. (2012). Mitochondria, maternal inheritance, and asymmetric fitness: Why males die younger.
BioEssays. Advance online publication. doi: 10.1002/bies.201200141
Wolff, J. N., White, D. J., Woodhams, M., White, H. E., & Gemmell, N. J. (2011). The strength and timing of the mitochondrial
bottleneck in salmon suggests a conserved mechanism in vertebrates. PLoS ONE, 6(5), e20522. doi: 10.1371/journal.
pone.0020522
Woodley, S. J., Latimer, C. P., Meikle, G. R., & Stringer, M. D. (2012). Articularis genus: An anatomic and MRI study in
cadavers. Journal of Bone & Joint Surgery (Am), 94(1), 59-67. doi: 10.2106/jbjs.k.00157
136
RESEARCH REPORT 2011/2012
Woon, J. T. K., Perumal, V., Maigne, J.-Y., & Stringer, M. D. (2012). CT morphology and morphometry of the normal adult
coccyx. European Spine Journal. Advance online publication. doi: 10.1007/s00586-012-2595-2
Woon, J. T. K., & Stringer, M. D. (2011). Clinical anatomy of the coccyx: A systematic review. Clinical Anatomy, 25(2), 158-167.
doi: 10.1002/ca.21216
Yan, S., Wang, C.-C., Li, H., Li, S.-L., Jin, L., and the Genographic Consortium, including Clarke, A. C., Matisoo-Smith, E. A.
(2011). An updated tree of Y-chromosome Haplogroup O and revised phylogenetic positions of mutations in P164 and
PK4. European Journal of Human Genetics, 19, 1013-1015. doi: 10.1038/ejhg.2011.64
Yang, K., Zheng, H., Qin, Z., Lu, Y., Farina, S. E., Li, S., … and the Genographic Consortium, including Clarke, A. C., MatisooSmith, E. A. (2011). Positive selection on mitochondrial M7 lineages among the Gelong people in Hainan. Journal of
Human Genetics, 56(3), 253-256. doi: 10.1038/jhg.2010.165
Yip, S. H., Eguchi, R., Grattan, D. R., & Bunn, S. J. (2012). Prolactin signalling in the mouse hypothalamus is primarily
mediated by signal transducer and activator of transcription factor 5b but not 5a. Journal of Neuroendocrinology, 24(12),
1484-1491. doi: 10.1111/j.1365-2826.2012.02357.x
Youngson, N. A., Vickaryous, N., van der Horst, A., Epp, T., Harten, S., Fleming, J. S., … Whitelaw, E. (2011). A missense
mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice. Mammalian Genome,
22(3-4), 235-248. doi: 10.1007/s00335-011-9317-7
Zhang, J., Moore, A. E., & Stringer, M. D. (2011). Iatrogenic upper limb nerve injuries: A systematic review. ANZ Journal of
Surgery, 81(4), 227-236. doi: 10.1111/j.1445-2197.2010.05597.x
Zheng, Y., Balabhadrapatruni, S., Baek, J. H., Chung, P., Gliddon, C., Zhang, M., Darlington, C. L., Napper, R., … Smith, P. F.
(2012). The effects of bilateral vestibular loss on hippocampal volume, neuronal number, and cell proliferation in rats.
Frontiers in Neurology, 3, 20. doi: 10.3389/fneur.2012.00020
Zheng, Y., Begum, S., Zhang, C., Fleming, K., Masumura, C., Zhang, M., Smith, P., Darlington, C. (2011). Increased BrdU
incorporation reflecting DNA repair, neuronal de-differentiation or possible neurogenesis in the adult cochlear nucleus
following bilateral cochlear lesions in the rat. Experimental Brain Research, 210(3-4), 477-487. doi: 10.1007/s00221-0102491-0
Zondag, L., Dearden, P. K., & Wilson, M. J. (2012). Deep sequencing and expression of microRNAs from early honeybee
(Apis mellifera) embryos reveals a role in regulating early embryonic patterning. BMC Evolutionary Biology, 12, 211. doi:
10.1186/1471-2148-12-211
Journal - Research Other
Al-Shaqsi, S., & Stringer, M. D. (2011). Do senior medical students know enough clinical anatomy? [Letter]. New Zealand
Medical Journal, 124(1337).
Alamri, Y., & Stringer, M. D. (2011). A high-rising epiglottis: A benign anatomical variant. Clinical Anatomy, 24(5), 652-654.
doi: 10.1002/ca.21145
Cornwall, J. (2011). Don’t ask, don’t tell: Who should promote body donation programmes in the public domain? [Editorial].
Australasian Medical Journal, 4(8), 458-459. doi: 10.4066/AMJ.2011.929
Cornwall, J., & Melloh, M. (2012). Do New Zealand nurses claim more lumbar spine injuries than the general population? A
retrospective study (1995-2009) [Letter]. New Zealand Medical Journal, 125(1348). Retrieved from http://journal.nzma.
org.nz/journal/125-1348/5038/content.pdf.
Grattan, D. (2011). A mother’s brain knows [Neuroendocinology Briefing 38]. Journal of Neuroendocrinology, 23(11), 11881189. doi: 10.1111/j.1365-2826.2011.02175.x
Hale, S. J. M., Hill, G. B., & Stringer, M. D. (2011). Sonographic anatomy of the subclavian vein: Does shoulder retraction
improve exposure? Anaesthesia & Intensive Care, 39(6), 1158-1160.
Jones, D. G., & Whitaker, M. I. (2012). The contested realm of displaying dead bodies [Commentary]. Journal of Medical Ethics.
Advance online publication. doi: 10.1136/medethics-2012-100983
Mirjalili, S. A., Hale, S. J. M., & Stringer, M. D. (2012). The surface anatomy of the central sulcus [Letter]. Journal of Clinical
Neuroscience, 19(10), 1467. doi: 10.1016/j.jocn.2012.03.001
Mirjalili, S. A., & Stringer, M. D. (2012). The need for an evidence-based reappraisal of surface anatomy [Viewpoint]. Clinical
Anatomy, 25(7), 816-818. doi: 10.1002/ca.22142
Moore, A. E., & Stringer, M. D. (2012). Venepuncture-associated peripheral nerve injuries [Letter]. Clinical Anatomy, 25(8),
1099. doi: 10.1002/ca.22148
Rao, P., Stringer, M. D., & Puntis, J. W. L. (2011). 11-year follow-up in biliopancreatic diversion for recurrent pancreatitis due
to lipoprotein lipase deficiency [Letter to the editor]. Journal of Pediatric Gastroenterology & Nutrition, 52(4), 499. doi:
10.1097/MPG.0b013e3181f01bb9
Sopoaga, F., Leon de la Barra, S., Van der Meer, J., Samalia, L., Carr, S., Delaibatiki, R., & Kirifi-Alai, T. N. (2011). Developing
a health workforce from an underserved population in New Zealand [Letter to the editor]. Australian & New Zealand
Journal of Public Health, 35(5), 494-495. doi: 10.1111/j.1753-6405.2011.00766.x
Stringer, M. D. (2012). The internal vertebral venous plexus [Letter to the editor]. Clinical Anatomy, 25(7), 912. doi: 10.1002/
ca.22137
Stringer, M. D. (2012). [Comment on: The genitofemoral nerve block: A method for hemiscrotal anaesthesia at the bedside].
Annals of the Royal College of Surgeons of England, 94(6), 453. doi: 10.1308/003588412x13373405385133
137
RESEARCH REPORT 2011/2012
Journal - Professional & Other Non-Research Articles
Martyn, H., Trotman, P., Barrett, A., & Nicholson, H. (2011). Meet your cadaver: Medical students watch an interview with
their dissection body. Student BMJ, 19, d2302. doi: 10.1136/sbmj.d2302
McGee, R. G., & Stringer, M. D. (2011). Google’s body browser: A useful addition to electronic anatomy resources? [Letter to
the editor]. ANZ Journal of Surgery, 81(11), 842. doi: 10.1111/j.1445-2197.2011.05866.x
Mirjalili, S. A. (2012). Reply to: Relationship of the lumbar lordosis angle to the abdominal aortic bifurcation and inferior vena
cava confluence levels [Letter to the editor]. Clinical Anatomy, 25(6), 791. doi: 10.1002/ca.22085
Moore, A. E., & Stringer, M. D. (2011). [Letter to the editor]. New Zealand Dental Journal, 107(4), 138.
Samalia, L., & Stringer, M. D. (2012). [Cover image]. Anatomical Sciences Education, 5(2). doi: 10.1002/ase.1271
Stringer, M. D. (2011). Thoughts on human variations [Letter to the editor]. Clinical Anatomy, 24(8), 942. doi: 10.1002/ca.21230
Stringer, M. D., & Lyall, P. (2012). Design, implementation, and evaluation of a Postgraduate Diploma in Surgical Anatomy.
Anatomical Sciences Education, 5(1), 48-54. doi: 10.1002/ase.1253
Awarded Doctoral Degree
Bosch, C. (2011). Transmission et plasticite au sein de la voie hyperdirecte des ganglions de la base [Transmission and plasticity
in the hyperdirect pathway of basal ganglia] (PhD). L’Universite Pierre et Marie Curie [Pierre and Marie Curie University],
Paris, France. 208p.
Osborne, A. J. (2011). Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its
association with fitness (PhD). University of Otago, Dunedin, New Zealand. 283p.
Pankhurst, M. W. (2011). Immune system modulation in the brain injury of the metallothionein-I/II null mutant mouse (PhD).
University of Tasmania, Hobart, Australia. 170p. Retrieved from http://eprints.utas.edu.au/11750/1/Pankhurst.pdf.
Rizwan, M. Z. (2012). Role of RFamide-related peptide-3 in the neuroendocrine regulation of the reproductive and stress axes
(PhD). University of Otago, Dunedin, New Zealand. 302p.
Otago School of Medical Sciences
Biochemistry
Edited Book - Research
Eaton-Rye, J. J., Tripathy, B. C., & Sharkey, T. D. (Eds.). (2011). Photosynthesis: Plastid biology, energy conversion and carbon
assimilation. New York: Springer, 856p. doi: 10.1007/978-94-007-1579-0
Chapter in Book - Research
Collins, L. J., Schönfeld, B., & Chen, X. S. (2011). The epigenetics of non-coding RNA. In T. Tollefsbol (Ed.), Handbook of
epigenetics: The new molecular and medical genetics (pp. 49-61). London: Academic Press. doi: 10.1016/B978-0-12-3757098.00004-6
Daly, T., Chen, X. S., & Penny, D. (2011). How old are RNA networks? In L. J. Collins (Ed.), RNA infrastructure and networks:
Advances in experimental medicine and biology (Vol. 722) (pp. 255-273). New York: Springer Science+Business Media. doi:
10.1007/978-1-4614-0332-6
McConnell, I. L., Eaton-Rye, J. J., & van Rensen, J. J. S. (2011). Regulation of Photosystem II electron transport by bicarbonate.
In J. J. Eaton-Rye, B. C. Tripathy, T. D. Sharkey (Ed.), Photosynthesis: Plastid biology, energy conversion and carbon
assimilation (pp. 475-500). New York: Springer. doi: 10.1007/978-94-007-1579-0
Chapter in Book - Other
Eaton-Rye, J. J. (2011). Contributions of Govindjee, 1970-1999. In J. J. Eaton-Rye, B. C. Tripathy, T. D. Sharkey (Ed.),
Photosynthesis: Plastid biology, energy conversion and carbon assimilation. New York: Springer. Advance online publication.
doi: 10.1007/978-94-007-1579-0
Journal - Research Article
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The pea GIGAS gene is a FLOWERING LOCUS T homolog necessary for graft-transmissible specification of flowering but
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Smith, D. J., Anderson, G. J., Lamont, I. L., Masel, P., Campbell, S. C., & Reid, D. W. (2012). Accurate assessment of systemic
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Journal - Professional & Other Non-Research Articles
Bentley, R. W., Keown, D., Merriman, T. R., Krishnan, M. R., Gearry, R. B., Barclay, M. L., Roberts, R. L., Day, A. S. (2011).
Vitamin D receptor gene polymorphism associated with inflammatory bowel disease in New Zealand males [Letter to the
editor]. Alimentary Pharmacology & Therapeutics, 33(7), 855-856. doi: 10.1111/j.1365-2036.2011.04588.x
Intellectual Property
Anjomshoaa, A., Reeve, A. E., Lin, Y.-H., & Black, M. A. (2011). Proliferation signature and prognosis for gastrointestinal
cancer. (562237).
Guilford, P. J., & Holyoake, A. J. (2011). Markers for detection of gastric cancer. (EP 1 649 064).
Guilford, P. J., Kerr, N. J., & Pollock, R. C. (2011). Urine markers for detection of bladder cancer. (553297).
Working Paper; Discussion Paper; Technical Report
Fitzgerald, R. P., Legge, M., & Frank, N. (2012). Custodians of eggs and embryos: A technical report of the social and ethical
meanings of the work of biological scientists working in HART. Dunedin, New Zealand: University of Otago. 30p.
Otago School of Medical Sciences
Microbiology and Immunology
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structure of the family. In A. M. Q. King, M. J. Adams, E. B. Carstens, & E. J. Lefkowitz (Eds.), Virus taxonomy:
Classification and nomenclature of viruses: Ninth report of the International Committee on Taxonomy of Viruses (pp. 10911102). San Diego, CA: Elsevier Academic Press.
Hammes, F., Berney, M., & Egli, T. (2011). Cultivation-independent assessment of bacterial viability. In S. Müller & T. Bley
(Eds.), Advances in biochemical engineering biotechnology: High resolution microbial single cell analytics (Vol. 124) (pp. 123150). Berlin, Germany: Springer. doi: 10.1007/10_2010_95
Kalweit, A., Przybilski, R., Seehafer, C., de la Peña, M., & Hammann, C. (2012). Characterization of hammerhead ribozyme
reactions. In J. S. Hartig (Ed.), Ribozymes: Methods and protocols: Methods in molecular biology (Vol. 848) (pp. 5-20). New
York: Springer. doi: 10.1007/978-1-61779-545-9
Mercer, A., & Fleming, S. (2011). Parapoxvirus: Poxviridae, Chordopoxvirinae. In C. Tidona & G. Darai (Eds.), The Springer
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Family: Poxviridae. In A. M. Q. King, M. J. Adams, E. B. Carstens, & E. J. Lefkowitz, (Eds.), Virus taxonomy: Classification
and nomenclature of viruses: Ninth report of the International Committee on Taxonomy of Viruses (pp. 291-309). San Diego,
CA: Elsevier Academic Press.
Tagg, J. R., Wescombe, P. A., & Burton, J. P. (2012). Streptococcus: A brief update on the current taxonomic status of the genus.
In S. Lahtinen, A.C. Ouwehand, S. Salminen, & A. von Wright (Eds.), Lactic acid bacteria: Microbiological and functional
aspects (4th ed.) (pp. 123-146). Boca Raton, FL: CRC Press.
Journal - Research Article
Al-Mahrous, M. M., Jack, R., Sandiford, S. K., Tagg, J. R., Beatson, S. A., & Upton, M. (2011). Identification of a haemolysinlike peptide with antibacterial activity using the draft genome sequence of Staphylococcus epidermidis strain A487. FEMS
Immunology & Medical Microbiology, 62(3), 273-282. doi: 10.1111/j.1574-695X.2011.00811.x
Ancelet, L. R., Aldwell, F. E., Rich, F. J., & Kirman, J. R. (2012). Oral vaccination with lipid-formulated BCG induces a
long-lived, multifunctional CD4+ T cell memory immune response. PLOS ONE, 7(9), e45888. doi: 10.1371/journal.
pone.0045888
Ancelet, L., Rich, F. J., Delahunt, B., & Kirman, J. R. (2012). Dissecting memory T cell responses to TB: Concerns using
adoptive transfer into immunodeficient mice. Tuberculosis, 92(5), 422-433. doi: 10.1016/j.tube.2012.05.008
Arcus, V. L., McKenzie, J. L., Robson, J., & Cook, G. M. (2011). The PIN-domain ribonucleases and the prokaryotic VapBC
toxin—antitoxin array. Protein Engineering, Design & Selection, 24(1-2), 33-40. doi: 10.1093/protein/gzq081
Aziz, M. A., Cabral, J. D., Brooks, H. J. L., Moratti, S. C., & Hanton, L. R. (2012). Antimicrobial properties of a chitosan
dextran-based hydrogel for surgical use. Antimicrobial Agents & Chemotherapy, 56(1), 280-287. doi: 10.1128/aac.05463-11
Bah, C. S. F., Fang, E. F., Ng, T. B., Mros, S., McConnell, M., & Bekhit, A. E.-D. A. (2011). Purification and characterization of a
rhamnose-binding chinook salmon roe lectin with antiproliferative activity toward tumor cells and nitric oxide-inducing
activity toward murine macrophages. Journal of Agricultural & Food Chemistry, 59(10), 5720-5728. doi: 10.1021/jf2004578
Baker, E. S., Luckner, S. R., Krause, K. L., Lambden, P. R., Clarke, I. N., & Ward, V. K. (2012). Inherent structural disorder and
dimerisation of murine norovirus NS1-2 protein. PLoS ONE, 7(2), e30534. doi: 10.1371/journal.pone.0030534
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Baker, N. J., Schofield, J. C., Caswell, M. D., & McLellan, A. D. (2011). Effects of early atipamezole reversal of medetomidine—
ketamine anesthesia in mice. Journal of the American Association for Laboratory Animal Science, 50(6), 916-920.
Bekhit, A. E.-D. A., Cheng, V. J., McConnell, M., Zhao, J. H., Sedcole, R., & Harrison, R. (2011). Antioxidant activities, sensory
and anti-influenza activity of grape skin tea infusion. Food Chemistry, 129, 837-845. doi: 10.1016/j.foodchem.2011.05.032
Berney, M., Weimar, M. R., Heikal, A., & Cook, G. M. (2012). Regulation of proline metabolism in mycobacteria and its role in
carbon metabolism under hypoxia. Molecular Microbiology, 84(4), 664-681. doi: 10.1111/j.1365-2958.2012.08053.x
Blower, T. R., Evans, T. J., Przybilski, R., Fineran, P. C., & Salmond, G. P. C. (2012). Viral evasion of a bacterial suicide system
by RNA–based molecular mimicry enables infectious altruism. PLoS Genetics, 8(10), e1003023. doi: 10.1371/journal.
pgen.1003023
Blower, T. R., Pei, X. Y., Short, F. L., Fineran, P. C., Humphreys, D. P., Luisi, B. F., & Salmond, G. P. C. (2011). A processed
noncoding RNA regulates an altruistic bacterial antiviral system. Nature Structural & Molecular Biology, 18(2), 185-191.
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Blower, T. R., Short, F. L., Rao, F., Mizuguchi, K., Pei, X. Y., Fineran, P. C., … Salmond, G. P. C. (2012). Identification and
classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids
Research, 40(13), 6158-6173. doi: 10.1093/nar/gks231
Broghammer, A., Krusell, L., Blaise, M., Sauer, J., Sullivan, J. T., Maolanon, N., … Ronson, C. W., … Stougaard, J. (2012).
Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding. PNAS, 109(34),
13859-13864. doi: 10.1073/pnas.1205171109
Burton, J. P., Cowley, S., Simon, R. R., McKinney, J., Wescombe, P. A., & Tagg, J. R. (2011). Evaluation of safety and human
tolerance of the oral probiotic Streptococcus salivarius K12: A randomized, placebo-controlled, double-blind study. Food &
Chemical Toxicology, 49, 2356-2364. doi: 10.1016/j.fct.2011.06.038
Burton, J. P., Wescombe, P. A., Cadieux, P. A., & Tagg, J. R. (2011). Beneficial microbes for the oral cavity: Time to harness the
oral streptococci? Beneficial Microbes, 2(2), 93-101. doi: 10.3920/BM2011.0002
Campbell, H. G., Slatter, T. L., Jeffs, A., Mehta, R., Rubio, C., Baird, M., & Braithwaite, A. W. (2012). Does Δ133p53 isoform
trigger inflammation and autoimmunity?. Cell Cycle, 11(3), 446-450. doi: 10.4161/cc.11.3.19054
Cheng, V. J., Bekhit, A. E.-D. A., McConnell, M., Mros, S., & Zhao, J. (2012). Effect of extraction solvent, waste fraction and
grape variety on the antimicrobial and antioxidant activities of extracts from wine residue from cool climate. Food
Chemistry, 134(1), 474-482. doi: 10.1016/j.foodchem.2012.02.103
Cross, M. L., Fleming, S. B., Cowan, P. E., Scobie, S., Whelan, E., Prada, D., Mercer, A. A., Duckworth, J. A. (2011). Vaccinia
virus as a vaccine delivery system for marsupial wildlife. Vaccine, 29(28), 4537-4543. doi: 10.1016/j.vaccine.2011.04.093
Czepluch, W., Dunn, A. C., Everitt, C. L., Dorer, D., Saunderson, S. C., Aldwell, F. E., & McLellan, A. D. (2012). Extracellular
forms of Mycobacterium bovis BCG in the mucosal lymphatic tissues following oral vaccination. International Journal of
Mycobacteriology. Advance online publication. doi: 10.1016/j.ijmyco.2012.11.004
D’Costa, Z. J., Jolly, C., Androphy, E. J., Mercer, A., Matthews, C. M., & Hibma, M. H. (2012). Transcriptional repression of
e-cadherin by human papillomavirus type 16 E6. PLOS ONE, 7(11), e48954. doi: 10.1371/journal.pone.0048954
D’Costa, Z. J., Leong, C.-M., Shields, J., Matthews, C., & Hibma, M. H. (2012). Screening of drugs to counteract human
papillomavirus 16 E6 repression of E-cadherin expression. Investigational New Drugs. Advance online publication. doi:
10.1007/s10637-012-9803-0
Dowd, G. C., Casey, P. G., Begley, M., Hill, C., & Gahan, C. G. M. (2011). Investigation of the role of ZurR in the physiology
and pathogenesis of Listeria monocytogenes. FEMS Microbiology Letters, 327(2), 118-125. doi: 10.1111/j.15746968.2011.02472.x
Dowd, G. C., Joyce, S. A., Hill, C., & Gahan, C. G. M. (2011). Investigation of the mechanisms by which Listeria monocytogenes
grows in porcine gallbladder bile. Infection & Immunity, 79(1), 369-379. doi: 10.1128/IAI.00330-10
Draper, L. A., Tagg, J. R., Hill, C., Cotter, P. D., & Ross, R. P. (2012). The spiFEG locus in Streptococcus infantarius subsp.
infantarius BAA-102 confers protection against nisin U. Antimicrobial Agents & Chemotherapy, 56(1), 573-578. doi:
10.1128/aac.05778-11
Dufour, M., McLeod, F. S. A., & Simmonds, R. S. (2011). Zoocin A facilitates the entry of antisense constructs into
Streptococcus mutans. FEMS Microbiology Letters, 317(1), 93-99. doi: 10.1111/j.1574-6968.2011.02220.x
Dutton, S., Fleming, S. B., Ueda, N., Heath, D. D., Hibma, M. H., & Mercer, A. A. (2012). Delivery of Echinococcus
granulosus antigen EG95 to mice and sheep using recombinant vaccinia virus. Parasite Immunology, 34(6), 312-317. doi:
10.1111/j.1365-3024.2012.01360.x
El Oirdi, M., El Rahman, T. A., Rigano, L., El Hadrami, A., Rodriguez, M. C., Daayf, F., … Bouarab, K. (2011). Botrytis cinerea
manipulates the antagonistic effects between immune pathways to promote disease development in tomato. Plant Cell,
23(6), 2405-2421. doi: 10.1105/tpc.111.083394
Enrique, R., Siciliano, F., Favaro, M. A., Gerhardt, N., Roeschlin, R., Rigano, L., … Marano, M. R. (2011). Novel demonstration
of RNAi in citrus reveals importance of citrus callose synthase in defence against Xanthomonas citri subsp. citri. Plant
Biotechnology Journal, 9(3), 394-407. doi: 10.1111/j.1467-7652.2010.00555.x
Fineran, P. C., & Charpentier, E. (2012). Memory of viral infections by CRISPR-Cas adaptive immune systems: Acquisition of
new information. Virology. Advance online publication. doi: 10.1016/j.virol.2012.10.003
Frampton, R., Aggio, R. B. M., Villas-Bôas, S. G., Arcus, V. L., & Cook, G. M. (2012). Toxin-antitoxin systems of Mycobacterium
smegmatis are essential for cell survival. Journal of Biological Chemistry, 287(8), 5340-5356. doi: 10.1074/jbc.M111.286856
Frampton, R. A., Pitman, A. R., & Fineran, P. C. (2012). Advances in bacteriophage-mediated control of plant pathogens.
International Journal of Microbiology, 2012, 326452. doi: 10.1155/2012/326452
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Frese, S. A., Benson, A. K., Tannock, G. W., Loach, D. M., Kim, J., Zhang, M., … Heng, N. C. K., … Walter, J. (2011). The
evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri. PLoS Genetics, 7(2), e1001314. doi:
10.1371/journal.pgen.1001314
Friebe, A., Friederichs, S., Scholz, K., Janssen, U., Scholz, C., Schlapp, T., Mercer, A., … Weber, O. (2011). Characterization
of immunostimulatory components of orf virus (parapoxvirus ovis). Journal of General Virology, 92(7), 1571-1584. doi:
10.1099/vir.0.028894-0
Gao, N., Jennings, P., Guo, Y., & Yuan, D. (2011). Regulatory role of natural killer (NK) cells on antibody responses to Brucella
abortus. Innate Immunity, 17(2), 152-163. doi: 10.1177/1753425910367526
Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., Kemp, R. A. (2012). Inflammatory
and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients.
International Journal of Cancer. Advance online publication. doi: 10.1002/ijc.27855
Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes
and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi:
10.3109/08982104.2011.637502
Gore, C., Custovic, A., Tannock, G. W., Munro, K., Kerry, G., Johnson, K., … Woodcock, A. (2012). Treatment and secondary
prevention effects of the probiotics Lactobacillus paracasei or Bifidobacterium lactis on early infant eczema: Randomized
controlled trial with follow-up until age 3 years. Clinical & Experimental Allergy, 42(1), 112-122. doi: 10.1111/j.13652222.2011.03885.x
Gristwood, T., McNeil, M. B., Clulow, J. S., Salmond, G. P. C., & Fineran, P. C. (2011). PigS and PigP regulate prodigiosin
biosynthesis in Serratia via differential control of divergent operons, which include predicted transporters of sulfurcontaining molecules. Journal of Bacteriology, 193(5), 1076-1085. doi: 10.1128/JB.00352-10
Gupta, S. K., Haigh, B. J., Griffin, F. J., & Wheeler, T. T. (2012). The mammalian secreted RNases: Mechanisms of action in host
defence. Innate Immunity, 19(1), 86-97. doi: 10.1177/1753425912446955
Heng, N. C. K., Haji-Ishak, N. S., Kalyan, A., Wong, A. Y. C., Lovrić, M., Bridson, J. M., Artamonova, J., Stanton, J.-A. L.,
Wescombe, P. A., Burton, J. P., Cullinan, M. P., Tagg, J. R. (2011). Genome sequence of the bacteriocin-producing oral
probiotic Streptococcus salivarius strain M18. Journal of Bacteriology, 193(22), 6402-6403. doi: 10.1128/jb.06001-11
Hibma, M. H. (2012). The immune response to papillomavirus during infection persistence and regression. Open Virology
Journal, 6(Suppl. 2), 241-248. doi: 10.2174/1874357901206010241
Hsu, L., Power, D., Upritchard, J., Burton, J., Friedlander, R., Horswell, J., … Kieser, J., Tompkins, G. (2012). Amplification of
oral streptococcal DNA from human incisors and bite marks. Current Microbiology, 65(2), 207-211. doi: 10.1007/s00284012-0148-x
Husain, M., & Harrod, K. S. (2011). Enhanced acetylation of alpha-tubulin in influenza A virus infected epithelial cells. FEBS
Letters, 585(1), 128-132. doi: 10.1016/j.febslet.2010.11.023
Jiwani, S., Wang, Y., Dowd, G. C., Gianfelice, A., Pichestapong, P., Gavicherla, B., … Ireton, K. (2012). Identification
of components of the host type IA phosphoinositide 3-kinase pathway that promote internalization of Listeria
monocytogenes. Infection & Immunity, 80(3), 1252-1266. doi: 10.1128/IAI.06082-11
Kalamorz, F., Keis, S., McMillan, D. G. G., Olsson, K., Stanton, J.-A., Stockwell, P., Black, M. A., … Cook, G. M. (2011). Draft
genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1. Journal of Bacteriology, 193(16),
4290-4291. doi: 10.1128/jb.05035-11
Kelly, S. J., Muszyński, A., Kawaharada, Y., Hubber, A. M., Sullivan, J. T., Sandal, N., … Ronson, C. W. (2012). Conditional
requirement for exopolysaccharide in the Mesorhizobium-Lotus symbiosis. Molecular Plant-Microbe Interactions, 26(3),
319-329. doi: 10.1094/mpmi-09-12-0227-r
Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations
in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer
Research, 30, 78. doi: 10.1186/1756-9966-30-78
Krittaphol, W., Wescombe, P. A., Thomson, C. D., McDowell, A., Tagg, J. R., & Fawcett, J. P. (2011). Metabolism of
L-selenomethionine and selenite by probiotic bacteria: In vitro and in vivo studies. Biological Trace Element Research, 144,
1358-1369. doi: 10.1007/s12011-011-9057-2
Lawley, B., & Tannock, G. W. (2012). Nucleic acid-based methods to assess the composition and function of the bowel
microbiota. Gastroenterology Clinics of North America. Advance online publication. doi: 10.1016/j.gtc.2012.08.010
Lester, K., & Simmonds, R. S. (2012). Zoocin A and lauricidin in combination reduce Streptococcus mutans growth in a
multispecies biofilm. Caries Research, 46(3), 185-193. doi: 10.1159/000337307
Mackintosh, C. G., Clark, R. G., Tolentino, B., de Lisle, G. W., Liggett, S., & Griffin, J. F. T. (2011). Immunological and
pathological responses of red deer resistant or susceptible genotypes, to experimental challenge with Mycobacterium
avium subsp. paratuberculosis. Veterinary Immunology & Immunopathology, 143(1-2), 131-142. doi: 10.1016/j.
vetimm.2011.06.035
Mackintosh, C., Clarke, G., Tolentino, B., Liggett, S., de Lisle, G., & Griffin, F. (2012). Longitudinal pathogenesis study of
young red deer (Cervus elaphus) after experimental challenge with Mycobacterium avium subsp. paratuberculosis (MAP).
Veterinary Medicine International, 2012, 931948. doi: 10.1155/2012/931948
Malamud, F., Torres, P. S., Roeschlin, R., Rigano, L. A., Enrique, R., Bonomi, H. R., … Vojnov, A. A. (2011). The Xanthomonas
axonopodis pv. citri flagellum is required for mature biofilm and canker development. Microbiology, 157(3), 819-829. doi:
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Marelli, M., Divitini, G., Collini, C., Ravagnan, L., Corbelli, G., Ghisleri, C., Gianfelice, A., … Lorenzelli, L. (2011). Flexible and
biocompatible microelectrode arrays fabricated by supersonic cluster beam deposition on SU-8. Journal of Micromechanics
& Microengineering, 21, 45013. doi: 10.1088/0960-1317/21/4/045013
Matejka, K. M., Bremer, P. J., Tompkins, G. R., & Brooks, H. J. L. (2012). Antibiotic susceptibility of Moraxella catarrhalis
biofilms in a continuous flow model. Diagnostic Microbiology & Infectious Disease, 74, 394-398. doi: 10.1016/j.
diagmicrobio.2012.08.021
McKee, S. J., Young, V. L., Clow, F. M., Hayman, C. M., Baird, M. A., Hermans, I. F., Young, S. L., Ward, V. K. (2012). Virus-like
particles and α-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses. Journal of
Controlled Release, 159(3), 338-345. doi: 10.1016/j.jconrel.2012.02.015
McKenzie, J. L., Duyvestyn, J. M., Smith, T., Bendak, K., Mackay, J., Cursons, R., Cook, G. M., Arcus, V. L. (2012).
Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. RNA, 18(6), 1267-1278.
doi: 10.1261/rna.031229.111
McKenzie, J. L., Robson, J., Berney, M., Smith, T. C., Ruthe, A., Gardner, P. P., Arcus, V. L., Cook, G. M. (2012). A vapBC toxinantitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria. Journal of Bacteriology, 194(9),
2189-2204. doi: 10.1128/jb.06790-11
McNeil, M. B., Clulow, J. S., Wilf, N. M., Salmond, G. P. C., & Fineran, P. C. (2012). SdhE is a conserved protein required
for the flavinylation of succinate dehydrogenase in bacteria. Journal of Biological Chemistry, 287(22), 18418-18428. doi:
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McNeil, M. B., & Fineran, P. C. (2012). Prokaryotic assembly factors for the attachment of flavin to complex II. Biochimica et
Biophysica Acta: Bioenergetics. Advance online publication. doi: 10.1016/j.bbabio.2012.09.003
Mengoni, E. S., Vichera, G., Rigano, L. A., Rodriguez-Puebla, M. L., Galliano, S. R., Cafferata, E. E., … Vojnov, A. A. (2011).
Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds
from Rosmarinus officinalis L. Fitoterapia, 82(3), 414-421. doi: 10.1016/j.fitote.2010.11.023
Morganti E, Collini, C., Cunaccia, R., Gianfelice, A., Odorizzi, L., Adami, A., … Milani, P. (2011). A dielectrophoresis-based
microdevice coated with nanostructured TiO2 for separation of particles and cells. Microfluid Nanofluid, 10(6), 12111221. doi: 10.1007/s10404-010-0751-8
Nixon, G., Blattner, K., Dawson, J., Dovey, S., Black, M. A., Wilkins, G., Dunn, A. C., McLellan, A. D. (2011). Streptokinase
antibodies in patients presenting with acute coronary syndrome in three rural New Zealand populations. Journal of
Clinical Pathology, 64, 426-429. doi: 10.1136/jcp.2010.085837
Preidis, G. A., Hill, C., Guerrant, R. L., Ramakrishna, B. S., Tannock, G. W., & Versalovic, J. (2011). Probiotics, enteric and
diarrheal diseases, and global health. Gastroenterology, 140(1), 8-14. doi: 10.1053/j.gastro.2010.11.010
Prendergast, K. A., & Kirman, J. R. (2012). Dendritic cell subsets in mycobacterial infection: Control of bacterial growth and
T cell responses. Tuberculosis. Advance online publication. doi: 10.1016/j.tube.2012.10.008
Przybilski, R., Richter, C., Gristwood, T., Clulow, J. S., Vercoe, R. B., & Fineran, P. C. (2011). Csy4 is responsible for CRISPR
RNA processing in Pectobacterium atrosepticum. RNA Biology, 8(3), 517-528. doi: 10.4161/rna.8.3.15190
Rich, F. J., Kuhn, S., Hyde, E. J., Harper, J. L., Ronchese, F., & Kirman, J. R. (2012). Induction of T cell responses and
recruitment of an inflammatory dendritic cell subset following tumor immunotherapy with Mycobacterium smegmatis.
Cancer Immunology, Immunotherapy, 61(12), 2333-2342. doi: 10.1007/s00262-012-1291-8
Richter, C., Chang, J. T., & Fineran, P. C. (2012). Function and regulation of clustered regularly interspaced short palindromic
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Richter, C., Gristwood, T., Clulow, J. S., & Fineran, P. C. (2012). In vivo protein interactions and complex formation in
the Pectobacterium atrosepticum subtype I-F CRISPR/Cas system. PLOS ONE, 7(12), e49549. doi: 10.1371/journal.
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Rintoul, J. L., Lemay, C. G., Tai, L.-H., Stanford, M. M., Falls, T. J., de Souza, C. T., … Mercer, A. A., … Bell, J. C. (2012). ORFV:
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Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2012). Cubosomes containing the
adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of
Controlled Release. Advance online publication. doi: 10.1016/j.jconrel.2012.10.020
Robinson, M. W., O’Brien, R., Mackintosh, C. G., Clark, R. G., & Griffin, J. F. T. (2011). Immunoregulatory cytokines are
associated with protection from immunopathology following Mycobacterium avium subspecies paratuberculosis infection
in red deer. Infection & Immunity, 79(5), 2089-2097. doi: 10.1128/IAI.00779-10
Rose, S. B., Lawton, B. A., Lanumata, T. S., Hibma, M., & Baker, M. G. (2012). Predictors of intent to vaccinate against HPV/
cervical cancer: A multi-ethnic survey of 769 parents in New Zealand. New Zealand Medical Journal, 125(1350). Retrieved
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Sims, I. M., Frese, S. A., Walter, J., Loach, D., Wilson, M., Appleyard, K., … Livingston, M., Baird, M., Cook, G., Tannock, G.
W. (2011). Structure and functions of exopolysaccharide produced by gut commensal Lactobacillus reuteri 100-23. ISME
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Slatter, T. L., Hung, N., Campbell, H., Rubio, C., Mehta, R., Renshaw, P., Williams, G., Wilson, M., … Jeffs, A., Royds, J. A.,
Baird, M. A., Braithwaite, A. W. (2011). Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like
isoform. Blood, 117(19), 5166-5177. doi: 10.1182/blood-2010-11-321851
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Sonnberg, S., Fleming, S. B., & Mercer, A. A. (2011). Phylogenetic analysis of the large family of poxvirus ankyrin-repeat
proteins reveals orthologue groups within and across chordopoxvirus genera. Journal of General Virology, 92(11), 25962607. doi: 10.1099/vir.0.033654-0
Tan, J. L., Ueda, N., Heath, D., Mercer, A. A., & Fleming, S. B. (2012). Development of orf virus as a bifunctional recombinant
vaccine: Surface display of Echinococcus granulosus antigen EG95 by fusion to membrane structural proteins. Vaccine,
30(2), 398-406. doi: 10.1016/j.vaccine.2011.10.079
Tang, R., Li, K., Wilson, M., Both, G. W., Taylor, J. A., & Young, S. L. (2012). Potent antietumor immunity in mice
induced by vaccination with an ovine Atadenovirus vector. Journal of Immunotherapy, 35(1), 32-41. doi: 10.1097/
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Taniguchi, N., Suzuki, T., Berney, M., Yoshida, M., & Cook, G. M. (2011). The regulatory C-terminal domain of subunit ε of
FoF1 ATP synthase is dispensable for growth and survival of Escherichia coli. Journal of Bacteriology, 193(8), 2046-2052.
doi: 10.1128/JB.01422-10
Tannock, G. W., Lawley, B., Munro, K., Lay, C., Taylor, C., Daynes, C., … Thomson-Fawcett, M. (2012). Comprehensive
analysis of the bacterial content of stool from patients with chronic pouchitis, normal pouches, or familial adenomatous
polyposis pouches. Inflammatory Bowel Diseases, 18(5), 925-934. doi: 10.1002/ibd.21936
Tannock, G. W., Tiong, I. S., Priest, P., Munro, K., Taylor, C., Richardson, A., & Schultz, M. (2011). Testing probiotic strain
Escherichia coli Nissle 1917 (Mutaflor) for its ability to reduce carriage of multidrug-resistant E. coli by elderly residents in
long-term care facilities. Journal of Medical Microbiology, 60(3), 366-370. doi: 10.1099/jmm.0.025874-0
Tannock, G. W., Wilson, C. M., Loach, D., Cook, G. M., Eason, J., O’Toole, P. W., … Lawley, B. (2012). Resource partitioning
in relation to cohabitation of Lactobacillus species in the mouse forestomach. ISME Journal, 6, 927-938. doi: 10.1038/
ismej.2011.161
Tayuan, C., Tannock, G. W., & Rodtong, S. (2011). Growth and exopolysaccharide production by Weissella sp. from low-cost
substitutes for sucrose. African Journal of Microbiology Research, 5(22), 3693-3701.
Ting, Y.-T., Coates, P. T., Walker, R. J., & McLellan, A. D. (2012). Urinary tubular biomarkers as potential early predictors of
renal allograft rejection. Nephrology, 17(1), 11-16. doi: 10.1111/j.1440-1797.2011.01536.x
Valnegri, P., Khelfaoui, M., Dorseuil, O., Bassani, S., Lagneaux, C., Gianfelice, A., … Passafaro, M. (2011). A circadian clock in
hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα. Nature Neuroscience, 14(10), 1293-1301.
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Vanga, B. R., Butler, R. C., Toth, I. K., Ronson, C. W., & Pitman, A. R. (2012). Inactivation of PbTopo IIIβ causes hyper-excision
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Warren, B., Dovey, S., & Griffin, F. (2011). The evidence behind more than a decade of policy recommending influenza
vaccination for young New Zealanders with long term medical conditions. Kai Tiaki Nursing Research, 2(1), 27-32.
Wescombe, P. A., Dyet, K. H., Dierksen, K. P., Power, D. A., Jack, R. W., Burton, J. P., Inglis, M. A., Wescombe, A. L., Tagg, J. R.
(2012). Salivaricin G32: A homolog of the prototype Streptococcus pyogenes nisin-like lantibiotic SA-FF22, produced by the
commensal species Streptococcus salivarius. International Journal of Microbiology, 2012, 738503. doi: 10.1155/2012/738503
Wescombe, P. A., Hale, J. D. F., Heng, N. C. K., & Tagg, J. R. (2012). Developing oral probiotics from Streptococcus salivarius.
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Wescombe, P. A., Upton, M., Renault, P., Wirawan, R. E., Power, D., Burton, J. P., … Tagg, J. R. (2011). Salivaricin 9, a new
lantibiotic produced by Streptococcus salivarius. Microbiology, 157(5), 1290-1299. doi: 10.1099/mic.0.044719-0
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the immunogenicity of tumour lysate-loaded dendritic cell vaccines by conjugation to virus-like particles. British Journal
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Wise, L. M., Inder, M. K., Real, N. C., Stuart, G. S., Fleming, S. B., & Mercer, A. A. (2012). The vascular endothelial growth
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Wong, C. K., Young, V. L., Kleffmann, T., & Ward, V. K. (2011). Genomic and proteomic analysis of invertebrate iridovirus type
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Young, W., Roy, N. C., Lee, J., Lawley, B., Otter, D., Henderson, G., … Tannock, G. W. (2012). Changes in bowel microbiota
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Zhang, X.-X., Chang, H., Tran, S. L., Gauntlett, J. C., Cook, G. M., & Rainey, P. B. (2012). Variation in transport explains
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150
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Journal - Research Other
Cook, G. M., & Heikal, A. (2012). Bridging the gap between a TB drug and its target. Science Translational Medicine, 4(150),
150fs33. doi: 10.1126/scitranslmed.3004816
McMillan, D. G. G., Ferguson, S. A., Dey, D., Schröder, K., Aung, H. L., Carbone, V., … Cook, G. M. (2011). A1Ao-ATP
synthase of Methanobrevibacter ruminantium couples sodium ions for ATP synthesis under physiological conditions.
Journal of Biological Chemistry, 286(46), 39882-39892. doi: 10.1074/jbc.M111.281675
Mo, M., Shahar, S., Fleming, S. B., & Mercer, A. A. (2012). How viruses affect the cell cycle through manipulation of the
APC/C. Trends in Microbiology, 20(9), 440-448. doi: 10.1016/j.tim.2012.05.007
Ramsay, J. P., & Salmond, G. P. C. (2012). Quorum sensing-controlled buoyancy through gas vesicles: Intracellular bacterial
microcompartments for environmental adaptation. Communicative & Integrative Biology, 5(1), 96-98. doi: 10.4161/
cib.18532
Journal - Professional & Other Non-Research Articles
Upton, M., Cotter, P., & Tagg, J. (2012). Antimicrobial peptides as therapeutic agents [Editorial]. International Journal of
Microbiology, 2012, 326503. doi: 10.1155/2012/326503
Intellectual Property
McConnell, M. A., Buchan, G. S., Fitzpatrick, C. E. A., & MacGibbon, A. K. H. (2011). Treating or preventing rotavirus
infection. (560524).
Awarded Doctoral Degree
Rigano, L. A. (2011). Aspectos moleculares de la interacción Xanthomonas-planta [Molecular aspects of Xanthomonas-plant
interaction] (PhD). Universidad de Buenos Aires, Buenos Aires, Argentina. 135p.
Otago School of Medical Sciences
Pharmacology & Toxicology
Chapter in Book - Research
Dzeyk, J., Yadav, B., & Rosengren, R. J. (2011). Experimental therapeutics for the treatment of triple negative breast cancer.
In E. Gunduz & M. Gunduz (Eds.), Breast cancer: Current and alternative therapeutic modalities (pp. 371-394). Rijeka,
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Greish, K., Thiagarajan, G., & Ghandehari, H. (2012). In vivo methods of nanotoxicology. In J. Reineke (Ed.), Nanotoxicity:
Methods and protocols: Methods in molecular biology (Vol. 926) (pp. 235-253). New York: Springer. doi: 10.1007/978-162703-002-1_17
Smith, P. F. (2011). The endocannabinoid system in the cochlear nucleus and its implications for tinnitus treatment. In A.
R. Møller, B. Langguth, D. De Ridder, & T. Kleinjung (Eds.), Textbook of tinnitus (pp. 639-647). New York: Springer. doi:
10.1007/978-1-60761-145-5_79
Journal - Research Article
Aitken, J. B., Lay, P. A., Duong, T. T. H., Aran, R., Witting, P. K., Harris, H. H., … Giles, G. I. (2012). Synchrotron radiation
induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen. Journal of Biological
Inorganic Chemistry, 17(4), 589-598. doi: 10.1007/s00775-012-0879-y
Ashton, J. C. (2012). Synthetic cannabinoids as drugs of abuse. Current Drug Abuse Reviews, 5(2), 158-168.
Ashton, J. C. (2012). Neuropathic pain: An evolutionary hypothesis. Medical Hypotheses, 78(5), 641-643. doi: 10.1016/j.
mehy.2012.01.044
Ashton, J. C. (2012). The atypical cannabinoid O-1602: Targets, actions, and the central nervous system. Central Nervous
System Agents in Medicinal Chemistry, 12(3), 233-239.
Babasaheb, Y., Taurin, S., Larsen, L., & Rosengren, R. J. (2012). RL66 a second-generation curcumin analog has potent in vivo
and in vitro anticancer activity in ERnegative breast cancer models. International Journal of Oncology, 41(5), 1723-1732.
doi: 10.3892/ijo.2012.1625
Baek, J. H., Zheng, Y., Darlington, C. L., & Smith, P. F. (2011). Cannabinoid CB1 receptor expression and affinity in the
rat hippocampus following bilateral vestibular deafferentation. Neuroscience Letters, 487(3), 330-334. doi: 10.1016/j.
neulet.2010.10.050
Breen, C., Brownjohn, P. W., & Ashton, J. C. (2012). The atypical cannabinoid O-1602 increases hind paw sensitisation
in the chronic constriction injury model of neuropathic pain. Neuroscience Letters, 508(2), 119-122. doi: 10.1016/j.
neulet.2011.12.039
Brownjohn, P. W., & Ashton, J. C. (2012). Spinal cannabinoid CB2 receptors as a target for neuropathic pain: An investigation
using chronic constriction injury. Neuroscience, 203, 180-193. doi: 10.1016/j.neuroscience.2011.12.028
Errington, A. C., & Connelly, W. M. (2011). Dendritic T-type Ca2+ channels: Giving a boost to thalamic reticular neurons.
Journal of Neuroscience, 31(15), 5551-5553. doi: 10.1523/JNEUROSCI.0067-11.2011
Fang, J., Greish, K., Qin, H., Liao, L., Nakamura, H., Takeya, M., & Maeda, H. (2012). HSP32 (HO-1) inhibitor, copoly(styrenemaleic acid)-zinc protoporphyrin IX, a water-soluble micelle as anticancer agent: In vitro and in vivo anticancer effect.
European Journal of Pharmaceutics & Biopharmaceutics, 81, 540-547. doi: 10.1016/j.ejpb.2012.04.016
151
RESEARCH REPORT 2011/2012
Gandhy, S. U., Kim, K., Larsen, L., Rosengren, R. J., & Safe, S. (2012). Curcumin and synthetic analogs induce reactive oxygen
species and decreases specificity protein (sp) transcription factors by targeting MicroRNAs. BMC Cancer, 12(1), 564. doi:
10.1186/1471-2407-12-564
Giles, N. M., Kumari, S., Gang, B. P., Yuen, C. W. W., Billaud, E. M. F., & Giles, G. I. (2012). The molecular design of
S-nitrosothiols as photodynamic agents for controlled nitric oxide release. Chemical Biology & Drug Design. Advance
online publication. doi: 10.1111/j.1747-0285.2012.01420.x
Giles, N. M., Kumari, S., Stamm, R., Patel, S., & Giles, G. I. (2012). A hydrogen peroxide electrode assay to measure thiol
peroxidase activity for organoselenium and organotellurium drugs. Analytical Biochemistry. Advance online publication.
doi: 10.1016/j.ab.2012.07.013
Gormley, A. J., Greish, K., Ray, A., Robinson, R., Gustafson, J. A., & Ghandehari, H. (2011). Gold nanorod mediated plasmonic
photothermal therapy: A tool to enhance macromolecular delivery. International Journal of Pharmaceutics, 415(1-2), 315318. doi: 10.1016/j.ijpharm.2011.05.068
Greish, K. (2012). Enhanced permeability and retention effect for selective targeting of anticancer nanomedicine: Are we there
yet? Drug Discovery Today: Technologies, 9(2), e161-e166. doi: 10.1016/j.ddtec.2011.11.010
Greish, K., Muller, K., IvanaJay, J., & Lee, D. H. (2011). The cooperative anticancer effect of dual styrenemaleic acid
nanomiceller system against pancreatic cancer. Journal of Nanomedicine & Nanotechnology, S4, 004. doi: 10.4172/21577439.S4-004
Greish, K., Ray, A., Bauer, H., Larson, N., Malugin, A., Pike, D., … Ghandehari, H. (2011). Anticancer and antiangiogenic
activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy. Journal of
Controlled Release, 151(3), 263-270. doi: 10.1016/j.jconrel.2010.12.015
Greish, K., Thiagarajan, G., Herd, H., Price, R., Bauer, H., Hubbard, D., … Ghandehari, H. (2012). Size and surface
charge significantly influence the toxicity of silica and dendritic nanoparticles. Nanotoxicology, 6(7), 713-723. doi:
10.3109/17435390.2011.604442
Harrison-Woolrych, M., Härmark, L., Tan, M., Maggo, S., & van Grootheest, K. (2012). Epistaxis and other haemorrhagic
events associated with the smoking cessation medicine varenicline: A case series from two national pharmacovigilance
centres. European Journal of Clinical Pharmacology, 68, 1065-1072. doi: 10.1007/s00228-012-1220-y
Harrison-Woolrych, M., Maggo, S., Tan, M., Savage, R., & Ashton, J. (2012). Cardiovascular events in patients taking
varenicline: A case series from intensive postmarketing surveillance in New Zealand. Drug Safety, 35(1), 33-43. doi:
10.2165/11597690-000000000-00000
Hellyer, S. D., Selwood, A., Rhodes, L., & Kerr, D. S. (2011). Marine algal pinnatoxins E and F cause neuromuscular block in an
in vitro hemidiaphragm preparation. Toxicon, 58, 693-699. doi: 10.1016/j.toxicon.2011.09.006
Hüfner, K., Strupp, M., Smith, P., Brandt, T., & Jahn, K. (2011). Spatial separation of visual and vestibular processing in
the human hippocampal formation. Annals of the New York Academy of Sciences, 1233, 177-186. doi: 10.1111/j.17496632.2011.06115.x
Imlach, W. L., Finch, S. C., Zhang, Y., Dunlop, J., & Dalziel, J. E. (2011). Mechanism of action of lolitrem B, a fungal endophyte
derived toxin that inhibits BK large conductance Ca2+-activated K+ channels. Toxicon, 57(5), 686-694. doi: 10.1016/j.
toxicon.2011.01.013
James, R., Searcy, J. L., Le Bihan, T., Martin, S. F., Gliddon, C. M., Povey, J., … Horsburgh, K. (2012). Proteomic analysis
of mitochondria in APOE transgenic mice and in response to an ischemic challenge. Journal of Cerebral Blood Flow &
Metabolism, 32, 164-176. doi: 10.1038/jcbfm.2011.120
Larson, N., Greish, K., Bauer, H., Maeda, H., & Ghandehari, H. (2011). Synthesis and evaluation of poly(styrene-co-maleic
acid) micellar nanocarriers for the delivery of tanespimycin. International Journal of Pharmaceutics, 420(1), 111-117. doi:
10.1016/j.ijpharm.2011.08.011
Leung, E., Rewcastle, G. W., Joseph, W. R., Rosengren, R. J., Larsen, L., & Baguley, B. C. (2012). Identification of cyclohexanone
derivatives that act as catalytic inhibitors of topoisomerase I: Effects on tamoxifen-resistant MCF-7 cancer cells.
Investigational New Drugs, 30, 2103-2112. doi: 10.1007/s10637-011-9768-4
Maggo, S., Clark, D., & Ashton, J. C. (2012). The effect of statins on performance in the Morris water maze in guinea pig.
European Journal of Pharmacology, 674(2-3), 287-293. doi: 10.1016/j.ejphar.2011.11.006
Maggo, S. D. S., Kennedy, M. A., & Clark, D. W. J. (2011). Clinical implications of pharmacogenetic variation on the effects of
statins. Drug Safety, 34(1), 1-19. doi: 10.2165/11584380-000000000-00000
Mandhane, S., Nayak, P., Soni, D., Jain, S., Ashton, J. C., & Rajamannar, T. (2012). Induction of glucose intolerance by acute
administration of rimonabant. Pharmacology, 89(5-6), 339-347. doi: 10.1159/000337731
Nair, S. M., Mishra, P., Norris, P. T., & Paul, C. (2012). The destination of Pacific Island health professional graduates from a
New Zealand university. Human Resources for Health, 10(24). doi: 10.1186/1478-4491-10-24
Nair, S. M., Rahman, R. M. A., Clarkson, A. N., Sutherland, B. A., Taurin, S., Sammut, I. A., & Appleton, I. (2011). Melatonin
treatment following stroke induction modulates L-arginine metabolism. Journal of Pineal Research, 51(3), 313-323. doi:
10.1111/j.1600-079X.2011.00891.x
Nayak, P. K., & Kerr, D. S. (2012). Low-dose GYKI-52466: Prophylactic preconditioning confers long-term neuroprotection
and functional recovery following hypoxic-ischaemic brain injury. Neuroscience. Advance online publication. doi:
10.1016/j.neuroscience.2012.11.063
Neo, P., Carter, D., Zheng, Y., Smith, P., Darlington, C., & McNaughton, N. (2012). Septal elicitation of hippocampal theta
rhythm did not repair cognitive and emotional deficits resulting from vestibular lesions. Hippocampus, 22(5), 1176-1187.
doi: 10.1002/hipo.20963
152
RESEARCH REPORT 2011/2012
Price, R., Gustafson, J., Greish, K., Cappello, J., McGill, L., & Ghandehari, H. (2012). Comparison of silk-elastinlike protein
polymer hydrogel and poloxamer in matrix-mediated gene delivery. International Journal of Pharmaceutics, 427(1), 97-104.
doi: 10.1016/j.ijpharm.2011.09.037
Ray, A., Larson, N., Pike, D. B., Grüner, M., Naik, S., Bauer, H., … Greish, K., Ghandehari, H. (2011). Comparison of active
and passive targeting of docetaxel for prostate cancer therapy by HPMA copolymer—RGDfK conjugates. Molecular
Pharmaceutics, 8(4), 1090-1099. doi: 10.1021/mp100402n
Rivers, J. R., Maggo, S. D. S., & Ashton, J. C. (2012). Neuroprotective effect of hydroxypropyl-β-cyclodextrin in hypoxiaischemia. NeuroReport, 23(3), 134-138. doi: 10.1097/WNR.0b013e32834ee47c
Rivers, J. R., Sutherland, B. A., & Ashton, J. C. (2011). Characterization of a rat hypoxia-ischemia model where duration
of hypoxia is determined by seizure activity. Journal of Neuroscience Methods, 197(1), 92-96. doi: 10.1016/j.
jneumeth.2011.02.002
Shelker, W., Belton, A., & Glue, P. (2011). Academic performance and career choices of older medical students at the University
of Otago. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4965/
content.pdf.
Smith, P. F. (2012). Dyscalculia and vestibular function. Medical Hypotheses. Advance online publication. doi: 10.1016/j.
mehy.2012.06.032
Smith, P. F. (2012). Interactions between the vestibular nucleus and the dorsal cochlear nucleus: Implications for tinnitus.
Hearing Research. Advance online publication. doi: 10.1016/j.heares.2012.08.006
Somers-Edgar, T. J., Taurin, S., Larsen, L., Chandramouli, A., Nelson, M. A., & Rosengren, R. J. (2011). Mechanisms for the
activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines.
Investigational New Drugs, 29(1), 87-97. doi: 10.1007/s10637-009-9339-0
Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., … Davies, M. J. (2012). Reduced metal ion
concentrations in atherosclerotic plaques from subjects with Type 2 diabetes mellitus. Atherosclerosis, 222(2), 512-518. doi:
10.1016/j.atherosclerosis.2012.03.015
Stiles, L., Zheng, Y., Darlington, C. L., & Smith, P. F. (2012). The effects of the D2 dopamine receptor antagonist, eticlopride,
on attention following bilateral vestibular deafferentation in the rat. Neuroscience Letters, 506(2), 193-197. doi: 10.1016/j.
neulet.2011.11.003
Stiles, L., Zheng, Y., Darlington, C. L., & Smith, P. F. (2012). The D2 dopamine receptor and locomotor hyperactivity following
bilateral vestibular deafferentation in the rat. Behavioural Brain Research, 227(1), 150-158. doi: 10.1016/j.bbr.2011.11.006
Sutherland, B. A., Shaw, O. M., Clarkson, A. N., Winburn, I. C., Errington, A. C., Dixon, C. L., Lees, G., Sammut, I. A.,
Appleton, I. (2011). Tin protoporphyrin provides protection following cerebral hypoxia-ischemia: Involvement of
alternative pathways. Journal of Neuroscience Research, 89(8), 1284-1294. doi: 10.1002/jnr.22661
Taurin, S., Nehoff, H., & Greish, K. (2012). Anticancer nanomedicine and tumor vascular permeability: Where is the missing
link? Journal of Controlled Release. Advance online publication. doi: 10.1016/j.jconrel.2012.07.013
Vranyac-Tramoundanas, A., Harrison, J. C., Sawant, P. M., Kerr, D. S., & Sammut, I. A. (2011). Ischemic cardiomyopathy
following seizure induction by domoic acid. American Journal of Pathology, 179(1), 141-154. doi: 10.1016/j.
ajpath.2011.03.017
Winburn, I. C., Gunatunga, K., McKernan, R. D., Walker, R. J., Sammut, I. A., & Harrison, J. C. (2012). Cell damage following
carbon monoxide releasing molecule exposure: Implications for therapeutic applications. Basic & Clinical Pharmacology &
Toxicology, 111(1), 31-41. doi: 10.1111/j.1742-7843.2012.00856.x
Yadav, B., & Greish, K. (2011). Selective inhibition of hemeoxygenase-1 as a novel therapeutic target for anticancer treatment.
Journal of Nanomedicine & Nanotechnology, S4, 005. doi: 10.4172/2157-7439.S4-005
Yadav, B., Taurin, S., Larsen, L., & Rosengren, R. J. (2012). RL71, a second-generation curcumin analog, induces apoptosis and
downregulates Akt in ER-negative breast cancer cells. International Journal of Oncology, 41(3), 1119-1127. doi: 10.3892/
ijo.2012.1521
Yu, T., Greish, K., McGill, L. D., Ray, A., & Ghandehari, H. (2012). Influence of geometry, porosity, and surface characteristics
of silica nanoparticles on acute toxicity: Their vasculature effect and tolerance threshold. ACS Nano, 6(3), 2289-2301. doi:
10.1021/nn2043803
Zadehvakili, B., Fawcett, J. P., & Giles, G. I. (2012). Synthesis, structure activity relationship studies and antioxidant activity
evaluation of some organochalcogen catalysts as novel GPx mimics. Free Radical Biology & Medicine, 53(Suppl. 1), S99.
doi: 10.1016/j.freeradbiomed.2012.08.206
Zheng, Y., Balabhadrapatruni, S., Baek, J. H., Chung, P., Gliddon, C., Zhang, M., Darlington, C. L., Napper, R., … Smith, P. F.
(2012). The effects of bilateral vestibular loss on hippocampal volume, neuronal number, and cell proliferation in rats.
Frontiers in Neurology, 3, 20. doi: 10.3389/fneur.2012.00020
Zheng, Y., Balabhadrapatruni, S., Masumura, C., Darlington, C. L., & Smith, P. F. (2011). Effects of the putative cognitiveenhancing ampakine, CX717, on attention and object recognition memory. Current Alzheimer Research, 8(8), 876-882. doi:
10.2174/156720511798192709
Zheng, Y., Begum, S., Zhang, C., Fleming, K., Masumura, C., Zhang, M., Smith, P., Darlington, C. (2011). Increased BrdU
incorporation reflecting DNA repair, neuronal de-differentiation or possible neurogenesis in the adult cochlear nucleus
following bilateral cochlear lesions in the rat. Experimental Brain Research, 210(3-4), 477-487. doi: 10.1007/s00221-0102491-0
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Zheng, Y., Cheung, I., & Smith, P. F. (2012). Performance in anxiety and spatial memory tests following bilateral vestibular
loss in the rat and effects of anxiolytic and anxiogenic drugs. Behavioural Brain Research, 235(1), 21-29. doi: 10.1016/j.
bbr.2012.07.025
Zheng, Y., Hamilton, E., Begum, S., Smith, P. F., & Darlington, C. L. (2011). The effects of acoustic trauma that can cause
tinnitus on spatial performance in rats. Neuroscience, 186, 48-56. doi: 10.1016/j.neuroscience.2011.04.052
Zheng, Y., Hamilton, E., McNamara, E., Smith, P. F., & Darlington, C. L. (2011). The effects of chronic tinnitus
caused by acoustic trauma on social behaviour and anxiety in rats. Neuroscience, 193, 143-153. doi: 10.1016/j.
neuroscience.2011.07.026
Zheng, Y., Hamilton, E., Stiles, L., McNamara, E., De Waele, C., Smith, P. F., & Darlington, C. L. (2011). Acoustic trauma that
can cause tinnitus impairs impulsive control but not performance accuracy in the 5-choice serial reaction time task in rats.
Neuroscience, 180, 75-84. doi: 10.1016/j.neuroscience.2011.02.040
Zheng, Y., McNamara, E., Stiles, L., Darlington, C. L., & Smith, P. F. (2012). Evidence that memantine reduces chronic tinnitus
caused by acoustic trauma in rats. Frontiers in Neurology, 3, 127. doi: 10.3389/fneur.2012.00127
Zheng, Y., Vagal, S., McNamara, E., Darlington, C. L., & Smith, P. F. (2012). A dose–response analysis of the effects of
L-baclofen on chronic tinnitus caused by acoustic trauma in rats. Neuropharmacology, 62, 940-946. doi: 10.1016/j.
neuropharm.2011.09.027
Journal - Research Other
Ashton, J. C. (2012). The use of knockout mice to test the specificity of antibodies for cannabinoid receptors [Letter].
Hippocampus, 22(3), 643-644. doi: 10.1002/hipo.20946
Ashton, J. C. (2012). When biostatisticis is a neo-inductionist barrier to science [Letter to the editor]. British Journal of
Pharmacology. Advance online publication. doi: 10.1111/j.1476-5381.2012.02035.x
Ashton, J. C. (2012). The BO test 25 years on [Letter]. Trends in Pharmacological Sciences, 33(10), 511-512. doi: 10.1016/j.
tips.2012.06.008
Ashton, J. C. (2012). Reply to Paul Smith: Breakthroughs do not arise from statistical perfectionism [Letter]. Trends in
Pharmacological Sciences, 33(11), 566-567. doi: 10.1016/j.tips.2012.08.007
Ashton, J. C. (2011). Reliability of immunolabelling in the determination of Huntington’s disease neuropathy [Letter to the
editor]. Brain, 134(11), e191. doi: 10.1093/brain/awr091
Ashton, J. C. (2011). Knockout controls and the specificity of cannabinoid CB2 receptor antibodies [Letter to the editor].
British Journal of Pharmacology, 163(6), 1113. doi: 10.1111/j.1476-5381.2010.01139.x
Brownjohn, P. W., & Ashton, J. C. (2012). A technical note for improving animal welfare and model validity in the chronic
constriction injury model of neuropathic pain [Letter to the editor]. European Journal of Pain. Advance online publication.
doi: 10.1002/j.1532-2149.2012.00199.x
Brownjohn, P. W., Ashton, J. C., & Chase, J. G. (2012). Microglial encapsulation of motor neurons in models of neuropathic
pain: A confound in pain assessment? [Letter to the editor]. European Journal of Pain, 16(3), 459-460. doi: 10.1002/j.15322149.2011.00101.x
Gliddon, C. M., & Rosengren, R. J. (2012). A laboratory course for teaching laboratory techniques, experimental design,
statistical analysis, and peer review process to undergraduate science students. Biochemistry & Molecular Biology Education.
Advance online publication. doi: 10.1002/bmb.20645
Glue, P., Gulati, A., Le Nedelec, M., & Duffull, S. (2011). Dose- and exposure-response to ketamine in depression [Letter to the
editor]. Biological Psychiatry, 70(4), e9-e10. doi: 10.1016/j.biopsych.2010.11.031
Maggo, S. (2011). Research highlights: Highlights from the latest articles in statin pharmacogenomics. Pharmacogenomics,
12(6), 773-778. doi: 10.2217/pgs.11.57
Schep, L. J., Slaughter, R. J., Temple, W. A., Nair, S. M., & Gee, P. (2011). Synthetic cannabinoid analogues: Not repeating
past mistakes [Letter]. New Zealand Medical Journal, 124(1332). Retrieved from http://journal.nzma.org.nz/
journal/124-1332/4619/content.pdf.
Smith, P. F. (2012). Statistical analysis in pharmacology is not always BO [Letter]. Trends in Pharmacological Sciences. Advance
online publication. doi: 10.1016/j.tips.2012.08.006
Smith, P. F. (2012). A note on the advantages of using linear mixed model analysis with maximal likelihood estimation over
repeated measures ANOVAs in psychopharmacology: Comment on Clark et al. (2012) [Letter to the editor]. Journal of
Psychopharmacology, 26(12), 1605-1607. doi: 10.1177/0269881112463471
Smith, P. F., Zheng, Y., & Darlington, C. L. (2012). Revisiting baclofen for the treatment of severe chronic tinnitus [Opinion].
Frontiers in Neurology, 3, 34. doi: 10.3389/fneur.2012.00034
Journal - Professional & Other Non-Research Articles
Ashton, J. C. (2012). Reply to Drummond & Vowler: Statistics or the philosophy of statistics? [Letter]. British Journal of
Pharmacology. Advance online publication. doi: 10.1111/j.1476-5381.2012.02135.x
154
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Otago School of Medical Sciences
Physiology
Chapter in Book - Research
Clarke, I. J., Campbell, R., Smith, J. T., Prevot, V., & Wray, S. (2012). Neuroendocrine control of reproduction. In G. Fink, D. W.
Pfaff & J. Levine (Eds.), Handbook of Neuroendocrinology (pp. 197-235). Elsevier. doi: 10.1016/b978-0-12-375097-6.10009-5
Journal - Research Article
Aggarwal, M., Hyland, B. I., & Wickens, J. R. (2012). Neural control of dopamine neurotransmission: Implications for
reinforcement learning. European Journal of Neuroscience, 35(7), 1115-1123. doi: 10.1111/j.1460-9568.2012.08055.x
Ainslie, P. N., Lucas, S. J. E., Fan, J.-L., Thomas, K. N., Cotter, J. D., Tzeng, Y. C., & Burgess, K. R. (2012). Influence of
sympathoexcitation at high altitude on cerebrovascular function and ventilatory control in humans. Journal of Applied
Physiology, 113(7), 1058-1067. doi: 10.1152/japplphysiol.00463.2012
Al-Salami, H., Butt, G., Tucker, I., Golocorbin-Kon, S., & Mikov, M. (2012). Probiotics decreased the bioavailability of the bile
acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats. European Journal
of Drug Metabolism & Pharmacokinetics, 37(2), 99-108. doi: 10.1007/s13318-011-0060-y
Andrews, G., Ainslie, P. N., Shepherd, K., Dawson, A., Swart, M., Lucas, S., & Burgess, K. R. (2012). The effect of partial
acclimatization to high altitude on loop gain and central sleep apnoea severity. Respirology, 17(5), 835-840. doi:
10.1111/j.1440-1843.2012.02170.x
Balut, C. M., Hamilton, K. L., & Devor, D. C. (2012). Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance,
Ca2+-activated K+ channels: A novel target for medicinal chemistry efforts? ChemMedChem, 7(10), 1741-1755. doi:
10.1002/cmdc.201200226
Beca, S., Helliwell, P. B., Simpson, J. A., Zhao, D., Farman, G. P., Jones, P. P., … Backx, P. H. (2011). Phosphodiesterase 4D
regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-Type Ca2+ current.
Circulation Research, 109(9), 1024-1030. doi: 10.1161/CIRCRESAHA.111.250464
Bhattarai, J. P., Park, S. A., Park, J. B., Lee, S. Y., Herbison, A. E., Ryu, P. D., & Han, S.-K. (2011). Tonic extrasynaptic GABAA
receptor currents control gonadotropin-releasing hormone neuron excitability in the mouse. Endocrinology, 152(4), 15511561. doi: 10.1210/en.2010-1191
Boix, J., & Cauli, O. (2012). Alteration of serotonin system by polychlorinated biphenyls exposure. Neurochemistry
International, 60(8), 809-816. doi: 10.1016/j.neuint.2012.03.003
Boix, J., Cauli, O., Leslie, H., & Felipo, V. (2011). Differential long-term effects of developmental exposure to polychlorinated
biphenyls 52, 138 or 180 on motor activity and neurotransmission: Gender dependence and mechanisms involved.
Neurochemistry International, 58(1), 69-77. doi: 10.1016/j.neuint.2010.10.014
Boix, J., Llansola, M., Cabrera-Pastor, A., & Felipo, V. (2011). Metabotropic glutamate receptor 5 modulates the nitric oxidecGMP pathway in cerebellum in vivo through activation of AMPA receptors. Neurochemistry International, 58(5), 599-604.
doi: 10.1016/j.neuint.2011.01.025
Bolter, C., Raniga, N., Waddell, J. N., & Kieser, J. (2012). Conservation of intraoral pressure changes during swallowing. Journal
of Dental Sciences. Advance online publication. doi: 10.1016/j.jds.2012.09.016
Bolter, C. P., Turner, M. J., & Barrett, C. J. (2011). The relationship between aortic baroreceptor activity and arterial pressure is
not monotonic. Journal of Physiological Sciences, 61(2), 151-160. doi: 10.1007/s12576-011-0132-4
Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2011). Differential changes in responses of hypothalamic and brainstem
neuronal populations to prolactin during lactation in the mouse. Biology of Reproduction, 84(4), 826-836. doi: 10.1095/
biolreprod.110.089185
Brown, R. S. E., Piet, R., Herbison, A. E., & Grattan, D. R. (2012). Differential actions of prolactin on electrical activity and
intracellular signal transduction in hypothalamic neurons. Endocrinology, 153(5), 2375-2384. doi: 10.1210/en.2011-2005
Brunelli, L., Campagna, R., Airoldi, L., Cauli, O., Llansola, M., Boix, J., … Pastorelli, R. (2012). Exploratory investigation
on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models.
Metabolic Brain Disease, 27(1), 37-49. doi: 10.1007/s11011-011-9268-4
Bull, P. M., Russell, J. A., Scott, V., & Brown, C. H. (2011). Apamin increases post-spike excitability of supraoptic nucleus
neurons in anaesthetized morphine-naïve rats and morphine-dependent rats: Consequences for morphine withdrawal
excitation. Experimental Brain Research, 212(4), 517-528. doi: 10.1007/s00221-011-2759-z
Cairns, S. P., Leader, J. P., & Loiselle, D. S. (2011). Exacerbated potassium-induced paralysis of mouse soleus muscle at 37°C
vis-À-vis 25°C: Implications for fatigue. Pflügers Archiv, 461(4), 469-479. doi: 10.1007/s00424-011-0927-4
Campagna, R., Brunelli, L., Airoldi, L., Fanelli, R., Hakansson, H., Heimeier, R. A., … Boix, J., … Pastorelli, R. (2011).
Cerebellum proteomics addressing the cognitive deficit of rats perinatally exposed to the food-relevant polychlorinated
biphenyl 138. Toxicological Sciences, 123(1), 170-179. doi: 10.1093/toxsci/kfr156
Campbell, R. E., Ducret, E., Porteous, R., Liu, X., Herde, M. K., Wellerhaus, K., … Herbison, A. E. (2011). Gap junctions
between neuronal inputs but not gonadotropin-releasing hormone neurons control estrous cycles in the mouse.
Endocrinology, 152(6), 2290-2301. doi: 10.1210/en.2010-1311
Cauli, O., López-Larrubia, P., Rodrigo, R., Agusti, A., Boix, J., …, & Felipo, V. (2011). Brain region-selective mechanisms
contribute to the progression of cerebral alterations in acute liver failure in rats. Gastroenterology, 140(2), 638-645. doi:
10.1053/j.gastro.2010.10.043
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Chan, H., Prescott, M., Ong, Z. Y., Herde, M. K., Herbison, A. E., & Campbell, R. E. (2011). Dendritic spine plasticity in
gonadatropin-releasing hormone (GnRH) neurons activated at the time of the preovulatory surge. Endocrinology, 152(12),
4906-4914. doi: 10.1210/en.2011-1522
Chang, T., Ke, Y., Ly, K., & McDonald, F. J. (2011). COMMD1 regulates the delta epithelial sodium channel (δENaC) through
trafficking and ubiquitination. Biochemical & Biophysical Research Communications, 411(3), 506-511. doi: 10.1016/j.
bbrc.2011.06.149
Cheong, R. Y., Kwakowsky, A., Barad, Z., Porteous, R., Herbison, A. E., & Ábrahám, I. M. (2012). Estradiol acts directly and
indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons.
Endocrinology, 153(8), 3792-3803. doi: 10.1210/en.2012-1232
Clarkson, J., & Herbison, A. E. (2011). Dual phenotype kisspeptin-dopamine neurones of the rostral periventricular area of
the third ventricle project to gonadotrophin-releasing hormone neurones. Journal of Neuroendocrinology, 23(4), 293-301.
doi: 10.1111/j.1365-2826.2011.02107.x
Clarkson, J., Shamas, S., Mallinson, S., & Herbison, A. E. (2012). Gonadal steroid induction of kisspeptin peptide expression
in the rostral periventricular area of the third ventricle during postnatal development in the male mouse. Journal of
Neuroendocrinology, 24(6), 907-915. doi: 10.1111/j.1365-2826.2012.02294.x
Condliffe, S. B., & Matteoli, M. (2011). Inactivation kinetics of voltage-gated calcium channels in glutamatergic neurons are
influenced by SNAP-25. Channels, 5(4), 304-307. Retrieved from http://www.landesbioscience.com/journals/channels/
article/16228/.
Constantin, S. (2011). Physiology of the gonadotrophin-releasing hormone (GnRH) neurone: Studies from embryonic GnRH
neurones. Journal of Neuroendocrinology, 23(6), 542-553. doi: 10.1111/j.1365-2826.2011.02130.x
Constantin, S., Jasoni, C., Romanò, N., Lee, K., & Herbison, A. E. (2012). Understanding calcium homeostasis in postnatal
gonadotropin-releasing hormone neurons using cell-specific Pericam transgenics. Cell Calcium, 51(3-4), 267-276. doi:
10.1016/j.ceca.2011.11.005
Constantin, S., Piet, R., Iremonger, K., Yeo, S. H., Clarkson, J., Porteous, R., & Herbison, A. E. (2012). GnRH neuron firing and
response to GABA in vitro depend on acute brain slice thickness and orientation. Endocrinology, 153(8), 3758-3769. doi:
10.1210/en.2012-1126
Davis, G. (2011). Baroreflex and somato-reflex control of blood pressure, heart rate, and renal sympathetic nerve activity in
the obese Zucker rat. Experimental Physiology, 96(7), 623-634. doi: 10.1113/expphysiol.2011.057638
de Croft, S., Piet, R., Mayer, C., Mai, O., Boehm, U., & Herbison, A. E. (2012). Spontaneous kisspeptin neuron firing in
the adult mouse reveals marked sex and brain region differences but no support for a direct role in negative feedback.
Endocrinology. Advance online publication. doi: 10.1210/en.2012-1616
Dejean, C., Arbuthnott, G., Wickens, J. R., Le Moine, C., Boraud, T., & Hyland, B. I. (2011). Power fluctuations in beta and
gamma frequencies in rat globus pallidus: Association with specific phases of slow oscillations and differential modulation
by dopamine D1 and D2 receptors. Journal of Neuroscience, 31(16), 6098-6107. doi: 10.1523/JNEUROSCI.3311-09.2011
Dinour, D., Bahn, A., Ganon, L., Ron, R., Geifman-Holtzman, O., Knecht, A., … Holtzman, E. J. (2011). URAT1 mutations
cause renal hypouricemia type 1 in Iraqi Jews. Nephrology Dialysis Transplantation, 26(7), 2175-2181. doi: 10.1093/ndt/
gfq722
Donnelly, J., Cowan, D. C., Yeoman, D. J., Lucas, S. J. E., Herbison, G. P., Thomas, K. N., Ainslie, P. N., Taylor, D. R. (2011).
Exhaled nitric oxide and pulmonary artery pressures during graded ascent to high altitude. Respiratory Physiology &
Neurobiology, 177(3), 213-217. doi: 10.1016/j.resp.2011.04.008
Donnelly, J., Lucas, S. J. E., Thomas, K. N., Galvin, S. D., & Ainslie, P. N. (2011). Profound hyperventilation and development
of periodic breathing during exceptional orthostatic stress in a 21-year-old man. Respiratory Physiology & Neurobiology,
177(1), 66-70. doi: 10.1016/j.resp.2011.02.012
Duan, W., Lee, K., Herbison, A. E., & Sneyd, J. (2011). A mathematical model of adult GnRH neurons in mouse brain and its
bifurcation analysis. Journal of Theoretical Biology, 276(1), 22-34. doi: 10.1016/j.jtbi.2011.01.035
Empson, R. M., & Knöpfel, T. (2012). Functional integration of calcium regulatory mechanisms at Purkinje neuron synapses.
Cerebellum, 11(3), 640-650. doi: 10.1007/s12311-010-0185-6
Fan, J.-L., Burgess, K. R., Thomas, K. N., Lucas, S. J. E., Cotter, J. D., Kayser, B., Peebles, K. C., Ainslie, P. N. (2012). Effects of
acetazolamide on cerebrovascular function and breathing stability at 5050m. Journal of Physiology, 590(5), 1213-1225. doi:
10.1113/jphysiol.2011.219923
Fan, J.-L., Burgess, K. R., Thomas, K. N., Peebles, K. C., Lucas, S. J. E., Lucas, R. A. I., Cotter, J. D., Ainslie, P. N. (2011).
Influence of indomethacin on the ventilatory and cerebrovascular responsiveness to hypoxia. European Journal of Applied
Physiology & Occupational Physiology, 111(4), 601-610. doi: 10.1007/s00421-010-1679-0
Fan, S., Harfoot, N., Bartolo, R. C., & Butt, A. G. (2012). CFTR is restricted to a small population of high expresser cells that
provide a forskolin-sensitive transepithelial Cl- conductance in the proximal colon of the possum, Trichosurus vulpecula.
Journal of Experimental Biology, 215, 1218-1230. doi: 10.1242/jeb.061176
Fleming, T. M., Scott, V., Naskar, K., Joe, N., Brown, C. H., & Stern, J. E. (2011). State-dependent changes in astrocyte
regulation of extrasynaptic NMDA receptor signalling in neurosecretory neurons. Journal of Physiology, 589(16), 39293941. doi: 10.1113/jphysiol.2011.207340
Gill, M., Bartolo, R. C., Demmers, K., Harfoot, N., Fan, S., & Butt, G. (2011). The distribution and expression of CFTR restricts
electrogenic anion secretion to the ileum of the brushtail possum, Trichosurus vulpecula. Journal of Experimental Biology,
214(Pt 11), 1943-1954. doi: 10.1242/jeb.053371
156
RESEARCH REPORT 2011/2012
Green, S., Thorp, R., Reeder, E. J., Donnelly, J., & Fordy, G. (2011). Venous occlusion plethysmography versus Doppler
ultrasound in the assessment of leg blood flow during calf exercise. European Journal of Applied Physiology & Occupational
Physiology, 111(8), 1889-1900. doi: 10.1007/s00421-010-1819-6
Hamilton, K. L. (2012). BLAP-tags, TUBEs and DUB-Chips: Combined novel technologies will advance molecular epithelial
physiology. Frontiers in Physiology, 3, 137. doi: 10.3389/fphys.2012.00137
Hamilton, K., & Devor, D. C. (2012). Basolateral membrane K+ channels in renal epithelial cells. American Journal of
Physiology: Renal Physiology, 302(9), F1069-F1081. doi: 10.1152/ajprenal.00646.2011
Hamilton, K. L., & Pao, A. C. (2012). βPix is a new player in renal physiology. Frontiers in Physiology, 3, 268. doi: 10.3389/
fphys.2012.00268
Han, S. Y., & Bolter, C. P. (2011). The muscarinic-activated potassium channel always participates in vagal slowing of the
guinea-pig sinoatrial pacemaker. Autonomic Neuroscience, 164(1-2), 96-100. doi: 10.1016/j.autneu.2011.05.009
Handa, R. J., Ogawa, S., Wang, J. M., & Herbison, A. E. (2012). Roles for oestrogen receptor β in adult brain function. Journal
of Neuroendocrinology, 24(1), 160-173. doi: 10.1111/j.1365-2826.2011.02206.x
Hazlett, J., Stamp, L. K., Merriman, T., Highton, J., & Hessian, P. A. (2011). IL-23R rs11209026 polymorphism modulates IL17A expression in patients with rheumatoid arthritis. Genes & Immunity. doi: 10.1038/gene.2011.80
Herbison, A. E., & Moenter, S. M. (2011). Depolarising and hyperpolarising actions of GABAA receptor activation on
GnRH neurons: Towards an emerging consensus. Journal of Neuroendocrinology, 23(7), 557-569. doi: 10.1111/j.13652826.2011.02145.x
Herde, M. K., Geist, K., Campbell, R. E., & Herbison, A. E. (2011). Gonadotropin-releasing hormone neurons extend complex
highly branched dendritic trees outside the blood-brain barrier. Endocrinology, 152(10), 3832-3841. doi: 10.1210/en.20111228
Igelström, K. M. (2012). Preclinical antiepileptic actions of selective serotonin reuptake inhibitors: Implications for clinical
trial design. Epilepsia, 53(4), 596-605. doi: 10.1111/j.1528-1167.2012.03427.x
Igelström, K. M., & Heyward, P. M. (2012). The antidepressant drug fluoxetine inhibits persistent sodium currents and
seizure-like events. Epilepsy Research. Advance online publication. doi: 10.1016/j.eplepsyres.2012.03.019
Igelström, K. M., & Heyward, P. M. (2012). Inhibition of hippocampal excitability by citalopram. Epilepsia. Advance online
publication. doi: 10.1111/j.1528-1167.2012.03660.x
Igelström, K. M., Shirley, C. H., & Heyward, P. M. (2011). Low-magnesium medium induces epileptiform activity in mouse
olfactory bulb slices. Journal of Neurophysiology, 106(5), 2593-2605. doi: 10.1152/jn.00601.2011
Iremonger, K. J., & Herbison, A. E. (2012). Initiation and propagation of action potentials in gonadotropin-releasing hormone
neuron dendrites. Journal of Neuroscience, 32(1), 151-158. doi: 10.1523/jneurosci.3739-11.2012
Iremonger, K. J., Kuzmiski, J. B., Baimoukhametova, D. V., & Bains, J. S. (2011). Dual regulation of anterograde and retrograde
transmission by endocannabinoids. Journal of Neuroscience, 31(33), 12011-12020. doi: 10.1523/JNEUROSCI.2925-11.2011
Jones, H., Lewis, N. C. S., Green, D. J., Ainslie, P. N., Lucas, S. J. E., Tzeng, Y.-C., Grant, E. J. M., Atkinson, G. (2011). α1adrenoreceptor activity does not explain lower morning endothelial-dependent, flow-mediated dilation in humans.
American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 300(6), R1437-R1442. doi: 10.1152/
ajpregu.00042.2011
Kazantseva, M., Highton, J., Stamp, L. K., & Hessian, P. A. (2012). Dendritic cells provide a potential link between smoking and
inflammation in rheumatoid arthritis. Arthritis Research & Therapy, 14, R208. doi: 10.1186/ar4046
Kieser, J., Bolter, C., Raniga, N., Waddell, J. N., Swain, M., & Farland, G. (2011). Tongue-palate interactions during swallowing.
Journal of Texture Studies, 42(2), 95-102. doi: 10.1111/j.1745-4603.2010.00274.x
Koshio, O., Nagao, T., Mabuchi, A., Ono, Y., & Suzuki, K. (2012). Apoptotic signaling in endothelial cells with neutrophil
activation. Molecular & Cellular Biochemistry, 363(1-2), 269-280. doi: 10.1007/s11010-011-1179-5
Köszegi, Z., & Ábrahám, I. M. (2012). Effect of ageing on post-lesion oestradiol treatment on mouse cholinergic neurons in
vivo. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/j.1365-2826.2012.02331.x
Köszegi, Z., Szegö, É. M., Cheong, R. Y., Tolod-Kemp, E., & Ábrahám, I. (2011). Postlesion estradiol treatment increases
cortical cholinergic innervations via estrogen receptor-α dependent nonclassical estrogen signaling in vivo. Endocrinology,
152(9), 3471-3482. doi: 10.1210/en.2011-1017
Kwakowsky, A., Herbison, A. E., & Ábrahám, I. M. (2012). The role of cAMP response element-binding protein in estrogen
negative feedback control of gonadotropin-releasing hormone neurons. Journal of Neuroscience, 32(33), 11309-11317. doi:
10.1523/jneurosci.1333-12.2012
Lee, K., Liu, X., & Herbison, A. E. (2012). Burst firing in gonadotropin-releasing hormone neurons does not require ionotropic
GABA or glutamate receptor activation. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/j.13652826.2012.02360.x
Lewis, N. C. S., Ainslie, P. N., Atkinson, G., Jones, H., Grant, E. J. M., & Lucas, S. J. E. (2012). The effect of time-ofday and sympathetic α1-blockade on orthostatic tolerance. Chronobiology International, 29(7), 882-890. doi:
10.3109/07420528.2012.699121
Lewis, N. C. S., Atkinson, G., Lucas, S. J. E., Grant, E. J. M., Jones, H., Tzeng, Y. C., Horsman, H., Ainslie, P. N. (2011). Is
there diurnal variation in initial and delayed orthostatic hypotension during standing and head-up tilt? Chronobiology
International, 28(2), 135-145. doi: 10.3109/07420528.2010.536283
Liu, X., & Herbison, A. E. (2011). Estrous cycle- and sex-dependent changes in pre- and postsynaptic GABAB control of GnRH
neuron excitability. Endocrinology, 152(12), 4856-4864. doi: 10.1210/en.2011-1369
157
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Liu, X., Porteous, R., d’Anglemont de Tassigny, X., Colledge, W. H., Millar, R., Petersen, S. L., & Herbison, A. E. (2011).
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls
gonadotropin-releasing hormone neuron excitability. Journal of Neuroscience, 31(7), 2421-2430. doi: 10.1523/
JNEUROSCI.5759-10.2011
Lucas, R. A. I., Ainslie, P. N., Morrison, S. A., & Cotter, J. D. (2012). Compression leggings modestly affect cardiovascular but
not cerebrovascular responses to heat and orthostatic stress in young and older adults. Age, 34(2), 439-449. doi: 10.1007/
s11357-011-9250-4
Lucas, S. J. E., Ainslie, P. N., Murrell, C. J., Thomas, K. N., Franz, E. A., & Cotter, J. D. (2012). Effect of age on exercise-induced
alterations in cognitive executive function: Relationship to cerebral perfusion. Experimental Gerontology, 47(8), 541-551.
doi: 10.1016/j.exger.2011.12.002
Lucas, S. J. E., Burgess, K. R., Thomas, K. N., Donnelly, J., Peebles, K. C., Lucas, R. A. I., Fan, J.-L., Cotter, J. D., … Ainslie, P. N.
(2011). Alterations in cerebral blood flow and cerebrovascular reactivity during 14 days at 5050 m. Journal of Physiology,
589(3), 741-753. doi: 10.1113/jphysiol.2010.192534
MacAnaney, O., Malone, J., Warmington, S., O’Shea, D., Green, S., & Egaña, M. (2011). Cardiac output is not related to
the slowed O2 uptake kinetics in type 2 diabetes. Medicine & Science in Sports & Exercise, 43(6), 935-942. doi: 10.1249/
MSS.0b013e3182061cdb
MacAnaney, O., Reilly, H., O’Shea, D., Egaña, M., & Green, S. (2011). Effect of type 2 diabetes on the dynamic response
characteristics of leg vascular conductance during exercise. Diabetes & Vascular Disease Research, 8(1), 12-21. doi:
10.1177/1479164110389625
McKelvey, K. J., Highton, J., & Hessian, P. A. (2011). Cell-specific expression of TLR9 isoforms in inflammation. Journal of
Autoimmunity, 36(1), 76-86. doi: 10.1016/j.jaut.2010.11.001
Millership, J. E., Devor, D. C., Hamilton, K. L., Balut, C. M., Bruce, J. I. E., & Fearon, I. M. (2011). Calcium-activated K+
channels increase cell proliferation independent of K+ conductance. American Journal of Physiology: Cell Physiology,
300(4), C792-C802. doi: 10.1152/ajpcell.00274.2010
Moore, A. M., Prescott, M., & Campbell, R. E. (2012). Estradiol negative and positive feedback in a prenatal androgen-induced
mouse model of polycystic ovarian syndrome. Endocrinology. Advance online publication. doi: 10.1210/en.2012-1954
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011).
Cardiorespiratory and cerebrovascular responses to head-up tilt II: Influence of age, training status and acute exercise.
Experimental Gerontology, 46(1), 1-8. doi: 10.1016/j.exger.2010.06.004
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011).
Cardiorespiratory and cerebrovascular responses to head-up tilt I: Influence of age and training status. Experimental
Gerontology, 46(1), 9-17. doi: 10.1016/j.exger.2010.06.005
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011). Syncope is
unrelated to supine and postural hypotension following prolonged exercise. European Journal of Applied Physiology &
Occupational Physiology, 111(3), 469-476. doi: 10.1007/s00421-010-1671-8
Murrell, C. J., Cotter, J. D., Thomas, K. N., Lucas, S. J. E., Williams, M. J. A., & Ainslie, P. N. (2012). Cerebral blood flow and
cerebrovascular reactivity at rest and during sub-maximal exercise: Effect of age and 12-week exercise training. Age.
Advance online publication. doi: 10.1007/s11357-012-9414-x
Nickerson, D. P., Terkildsen, J. R., Hamilton, K. L., & Hunter, P. J. (2011). A tool for multi-scale modelling of the renal nephron.
Interface Focus, 1, 417-425. doi: 10.1098/rsfs.2010.0032
Park, S. J., Kleffmann, T., & Hessian, P. A. (2011). The G82S polymorphism promotes glycosylation of the receptor for
advanced glycation end products (RAGE) at Asn81: A comparison of wild-type RAGE with the G82S polymorphic variant.
Journal of Biological Chemistry, 286(24), 21384-21392. doi: 10.1074/jbc.M111.241281
Piccoli, G., Condliffe, S. B., Bauer, M., Giesert, F., Boldt, K., De Astis, S., … Ueffing, M. (2011). LRRK2 controls synaptic
vesicle storage and mobilization within the recycling pool. Journal of Neuroscience, 31(6), 2225-2237. doi: 10.1523/
JNEUROSCI.3730-10.2011
Piet, R., Garenne, A., Farrugia, F., Le Masson, G., Marsicano, G., Chavis, P., & Manzoni, O. J. (2011). State-dependent,
bidirectional modulation of neural network activity by endocannabinoids. Journal of Neuroscience, 31(46), 16591-16596.
doi: 10.1523/jneurosci.4297-11.2011
Porteous, R., Petersen, S. L., Yeo, S. H., Bhattarai, J. P., Ciofi, P., D’anglemont de Tassigny, X., … Herbison, A. E. (2011).
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse
hypothalamus. Journal of Comparative Neurology, 519(17), 3456-3469. doi: 10.1002/cne.22716
Quennell, J. H., Howell, C. S., Roa, J., Augustine, R. A., Grattan, D. R., & Anderson, G. M. (2011). Leptin deficiency and dietinduced obesity reduce hypothalamic kisspeptin expression in mice. Endocrinology, 152(4), 1541-1550. doi: 10.1210/
en.2010-1100
Reeder, E. J., & Green, S. (2012). Dynamic response characteristics of hyperaemia in the human calf muscle: Effect of exercise
intensity and relation to electromyographic activity. European Journal of Applied Physiology. Advance online publication.
doi: 10.1007/s00421-012-2362-4
Rizwan, M. Z., Poling, M. C., Corr, M., Cornes, P. A., Augustine, R. A., Quennell, J. H., … Anderson, G. M. (2012). RFamiderelated peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action.
Endocrinology, 153(8), 3770-3779. doi: 10.1210/en.2012-1133
158
RESEARCH REPORT 2011/2012
Roa, J., & Herbison, A. E. (2012). Direct regulation of GnRH neuron excitability by arcuate nucleus POMC and NPY neuron
neuropeptides in female mice. Endocrinology. Advance online publication. doi: 10.1210/en.2012-1470
Roa, J., Navarro, V. M., & Tena-Sempere, M. (2011). Kisspeptins in reproductive biology: Consensus knowledge and recent
developments. Biology of Reproduction, 85(4), 650-660. doi: 10.1095/biolreprod.111.091538
Romanò, N., & Herbison, A. E. (2012). Activity-dependent modulation of GnRH neuron activity by acute estradiol. Journal of
Neuroendocrinology. Advance online publication. doi: 10.1111/j.1365-2826.2012.02342.x
Roome, C. J., Knöpfel, T., & Empson, R. M. (2012). Functional contributions of the plasma membrane calcium ATPase and the
sodium-calcium exchanger at mouse parallel fibre to Purkinje neuron synapses. European Journal of Physiology. Advance
online publication. doi: 10.1007/s00424-012-1172-1
Roome, C. J., Power, E. M., & Empson, R. M. (2012). Transient reversal of the sodium-calcium exchanger boosts presynaptic
calcium and synaptic transmission at a cerebellar synapse. Journal of Neurophysiology. Advance online publication. doi:
10.1152/jn.00854.2012
Ross, E. Z., Cotter, J. D., Wilson, L., Fan, J.-L., Lucas, S. J. E., & Ainslie, P. N. (2012). Cerebrovascular and corticomotor
function during progressive passive hyperthermia in humans. Journal of Applied Physiology, 112(5), 748-758. doi: 10.1152/
japplphysiol.00988.2011
Ruan, M., Russell, J. A., & Brown, C. H. (2011). Acute morphine administration and withdrawal from chronic morphine
increase afterdepolarization amplitude in rat supraoptic nucleus neurons in hypothalamic explants. Neuropharmacology,
61, 789-797. doi: 10.1016/j.neuropharm.2011.05.025
Russell, C. L., Semerdjieva, S., Empson, R. M., Austen, B. M., Beesley, P. W., & Alifragis, P. (2012). Amyloid-β acts as a regulator
of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. PLOS ONE, 7(8), e43201. doi:
10.1371/journal.pone.0043201
Schulz, J. M., Pitcher, T. L., Savanthrapadian, S., Wickens, J. R., Oswald, M. J., & Reynolds, J. N. J. (2011). Enhanced highfrequency membrane potential fluctuations control spike output in striatal fast-spiking interneurones in vivo. Journal of
Physiology, 589(17), 4365-4381. doi: 10.1113/jphysiol.2011.212944
Schwenke, D. O., Gray, E. A., Pearson, J. T., Sonobe, T., Ishibashi-Ueda, H., Campillo, I., … Shirai, M. (2011). Exogenous
ghrelin improves blood flow distribution in pulmonary hypertension: Assessed using synchrotron radiation
microangiography. Pflügers Archiv, 462(3), 397-406. doi: 10.1007/s00424-011-0992-8
Schwenke, D. O., Pearson, J. T., Sonobe, T., Ishibashi-Ueda, H., Shimouchi, A., Kangawa, K., … Shirai, M. (2011). Role of Rhokinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension. Journal of
Applied Physiology, 110(4), 901-908. doi: 10.1152/japplphysiol.01318.2010
Schwenke, D. O., Tokudome, T., Kishimoto, I., Horio, T., Cragg, P. A., Shirai, M., & Kangawa, K. (2012). One dose of ghrelin
prevents the acute and sustained increase in cardiac sympathetic tone after myocardial infarction. Endocrinology, 153(5),
2436-2443. doi: 10.1210/en.2011-2057
Schwirtlich, M., Kwakowsky, A., Emri, Z., Antal, K., Lacza, Z., Cselenyák, A., … Szabó, G. (2011). GABAergic signaling in
primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation. Cell Calcium, 50(4), 381-392.
doi: 10.1016/j.ceca.2011.07.002
Scott, V., & Brown, C. H. (2011). Kisspeptin activation of supraoptic nucleus neurons in Vivo. Endocrinology, 152(10), 38623870. doi: 10.1210/en.2011-1181
Senatore, A., Colleoni, S., Verderio, C., Restelli, E., Morini, R., Condliffe, S. B., … Chiesa, R. (2012). Mutant PrP suppresses
glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α2δ-1 subunit.
Neuron, 74(2), 300-313. doi: 10.1016/j.neuron.2012.02.027
Sheard, P. W., & Anderson, R. D. (2012). Age-related loss of muscle fibres is highly variable amongst mouse skeletal muscles.
Biogerontology, 13(2), 157-167. doi: 10.1007/s10522-011-9365-0
Smeding, L., van der Laarse, W. J., van Veelen, T. A., Lamberts, R. R., Niessen, H. W. M., Kneyber, M. C. J., … Plötz, F. B.
(2012). Early myocardial dysfunction is not caused by mitochondrial abnormalities in a rat model of peritonitis. Journal of
Surgical Research, 176(1), 178-184. doi: 10.1016/j.jss.2011.05.055
Sonobe, T., Schwenke, D. O., Pearson, J. T., Yoshimoto, M., Fujii, Y., Umetani, K., & Shirai, M. (2011). Imaging of the closedchest mouse pulmonary circulation using synchrotron radiation microangiography. Journal of Applied Physiology, 111(1),
75-80. doi: 10.1152/japplphysiol.00205.2011
Stamp, L. K., Hazlett, J., Roberts, R. L., Frampton, C., Highton, J., & Hessian, P. A. (2012). Adenosine receptor expression in
rheumatoid synovium: A basis for methotrexate action. Arthritis Research & Therapy, 14, R138. doi: 10.1186/ar3871
Szegö, É. M., Csorba, A., Janáky, T., Kékesi, K. A., Ábrahám, I. M., Mórotz, G. M., … Juhász, G. D. (2011). Effects of estrogen
on beta-amyloid-induced cholinergic cell death in the nucleus basalis magnocellularis. Neuroendocrinology, 93(2), 90-105.
doi: 10.1159/000321119
Tasker, J. G., Oliet, S. H. R., Bains, J. S., Brown, C. H., & Stern, J. E. (2012). Glial regulation of neuronal function: From synapse
to systems physiology. Journal of Neuroendocrinology, 24(4), 566-576. doi: 10.1111/j.1365-2826.2011.02259.x
Tzeng, Y. C., Ainslie, P. N., Cooke, W. H., Peebles, K. C., Willie, C. K., MacRae, B. A., … Horsman, H. M., Richards, C. A.
(2012). Assessment of cerebral autoregulation: The quandary of quantification. American Journal of Physiology: Heart &
Circulatory Physiology, 303(6), H658-H671. doi: 10.1152/ajpheart.00328.2012
Wang, R., Zhong, X., Meng, X., Koop, A., Tian, X., Jones, P. P., … Chen, S. R. W. (2011). Localization of the dantrolene-binding
sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor.
Journal of Biological Chemistry, 286(14), 12202-12212. doi: 10.1074/jbc.M110.194316
159
RESEARCH REPORT 2011/2012
Wickens, J. R., Hyland, B. I., & Tripp, G. (2011). Animal models to guide clinical drug development in ADHD: Lost in
translation? British Journal of Pharmacology, 164, 1107-1128. doi: 10.1111/j.1476-5381.2011.01412.x
Willie, C. K., Colino, F. L., Bailey, D. M., Tzeng, Y. C., Binsted, G., Jones, L. W., … Lucas, S. J., … Ainslie, P. N. (2011). Utility
of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function. Journal of Neuroscience
Methods, 196(2), 221-237. doi: 10.1016/j.jneumeth.2011.01.011
Yeo, S.-H., & Herbison, A. E. (2011). Projections of arcuate nucleus and rostral periventricular kisspeptin neurons in the adult
female mouse brain. Endocrinology, 152(6), 2387-2399. doi: 10.1210/en.2011-0164
Zhou, Q., Xiao, J., Jiang, D., Wang, R., Vembaiyan, K., Wang, A., … Jones, P. P., … Chen, S. R. W. (2011). Carvedilol and its new
analogs suppress arrhythmogenic store overload—induced Ca2+ release. Nature Medicine, 17, 1003-1009. doi: 10.1038/
nm.2406
Journal - Research Other
Hamilton, K. L. (2011). Ussing’s “little chamber”: 60 years+ old and counting. Frontiers in Physiology, 2, 6. doi: 10.3389/
fphys.2011.00006
Herbison, A. E. (2011). Journal of Neuroendocrinology impact factor reaches 4.65! Who cares? [Editorial]. Journal of
Neuroendocrinology, 23(10), 861-862. doi: 10.1111/j.1365-2826.2011.02201.x
Panzica, G. C., Balthazart, J., Frye, C. A., Garcia-Segura, L. M., Herbison, A. E., Mensah-Nyagan, A. G., … Melcangi, R. C.
(2012). Milestones on steroids and the nervous system: 10 years of basic and translational research [Editorial]. Journal of
Neuroendocrinology, 24(1), 1-15. doi: 10.1111/j.1365-2826.2011.02265.x
Schultz, M., & Butt, A. G. (2012). Is the north to south gradient in inflammatory bowel disease a global phenomenon? Expert
Review of Gastroenterology & Hepatology, 6(4), 445-447. doi: 10.1586/egh.12.31
Journal - Professional & Other Non-Research Articles
de Vries, G. J., Veenema, A. H., & Brown, C. H. (2012). Vasopressin and oxytocin: Keys to understanding the neural control of
physiology and behaviour [Editorial]. Journal of Neuroendocrinology, 24(4), 527. doi: 10.1111/j.1365-2826.2012.02305.x
Dunedin School of Medicine
Dean’s Department
Journal - Research Article
Gillespie, L. D., Robertson, M. C., Gillespie, W. J., Sherrington, C., Gates, S., Clemson, L. M., & Lamb, S. E. (2012).
Interventions for preventing falls in older people living in the community (Review). Cochrane Database of Systematic
Reviews, 9, CD007146. doi: 10.1002/14651858.CD007146.pub3
Herbison, P., Hay-Smith, J., & Gillespie, W. J. (2011). Meta-analyses of small numbers of trials often agree with longer-term
results. Journal of Clinical Epidemiology, 64(2), 145-153. doi: 10.1016/j.jclinepi.2010.02.017
Herbison, P., Hay-Smith, J., & Gillespie, W. J. (2011). Different methods of allocation to groups in randomized trials are
associated with different levels of bias. A meta-epidemiological study. Journal of Clinical Epidemiology, 64(10), 1070-1075.
doi: 10.1016/j.jclinepi.2010.12.018
Sopoaga, F., Connor, J. L., Dockerty, J. D., Adams, J., & Anderson, L. (2012). Training medical students in Pacific health
through an immersion programme in New Zealand. New Zealand Medical Journal, 125(1349). Retrieved from http://
journal.nzma.org.nz/journal/125-1349/5053/content.pdf.
Taylor, R. W., Williams, S. M., Carter, P. J., Goulding, A., Gerrard, D. F., & Taylor, B. J. (2011). Changes in fat mass and fat-free
mass during the adiposity rebound: FLAME study. International Journal of Pediatric Obesity, 6(2-2), e243-e251. doi:
10.3109/17477166.2010.549488
Journal - Research Other
Kieser, D. C., Theis, J. C., & van Rij, A. M. (2011). A combined approach to the excision of sciatic notch dumb-bell tumours.
ANZ Journal of Surgery, 81(9), 650. doi: 10.1111/j.1445-2197.2011.05836.x
Paterson, R., & Adams, J. (2011). Professional burnout: A regulatory perspective [Viewpoint]. New Zealand Medical Journal,
124(1333).
Dunedin School of Medicine
General Practice and Rural Health
Journal - Research Article
Blattner, K., & Ward, C. (2011). Point of care testing in Hokianga Hospital or ‘How to get a good night’s sleep in a lab-free
zone’. New Zealand Journal of Medical Laboratory Science, 65, 39-41.
Cariga, P., Huang, W. H. C., & Ranta, A. (2011). Safety and efficiency of non-contact first specialist assessment in neurology.
New Zealand Medical Journal, 124(1347). Retrieved from http://journal.nzma.org.nz/journal/124-1347/4989/content.pdf.
Copland, J. A., Craw, S. M., & Herbison, P. (2012). Low-lying placenta: Who should be recalled for a follow-up scan? Journal of
Medical Imaging & Radiation Oncology, 56(2), 158-162. doi: 10.1111/j.1754-9485.2012.02350.x
Cunningham, W., & Wilson, H. (2011). Complaints, shame and defensive medicine. BMJ Quality & Safety, 20(5), 449-452. doi:
10.1136/bmjqs.2011.051722
160
RESEARCH REPORT 2011/2012
Cunningham, W., & Wilson, H. (2011). Republished original viewpoint: Complaints, shame and defensive medicine.
Postgraduate Medical Journal, 87(1034), 837-840. doi: 10.1136/pgmj.2011.051722rep
Dovey, S., Hall, K., Makeham, M., Rosser, W., Kuzel, A., van Weel, C., … Phillips, R. (2011). Seeking ethical approval for an
international study in primary care patient safety. British Journal of General Practice, 61(585), e197-e204. doi: 10.3399/
bjgp11X567144
Dovey, S., Tilyard, M., Cunningham, W., & Williamson, M. (2011). Public and private funding of general practice services for
children and adolescents in New Zealand. Health Policy, 103, 24-30. doi: 10.1016/j.healthpol.2010.09.003
Dovey, S. M., & Wallis, K. A. (2011). Incident reporting in primary care: Epidemiology or culture change? BMJ Quality &
Safety, 20(12), 1001-1003. doi: 10.1136/bmjqs-2011-000465
Egan, R., MacLeod, R., Jaye, C., McGee, R., Baxter, J., & Herbison, P. (2011). What is spirituality? Evidence from a New Zealand
hospice study. Mortality, 16(4), 307-324. doi: 10.1080/13576275.2011.613267
Egnew, T. R., & Wilson, H. J. (2011). Role modeling the doctor-patient relationship in the clinical curriculum. Family
Medicine, 43(2), 99-105.
Gauld, R., Dovey, S., Tilyard, M., & Tomlin, A. (2011). How physicians can drive comparative-effectiveness research: Lessons
from New Zealand [Commentary]. American Journal of Medicine, 124(2), 93-94. doi: 10.1016/j.amjmed.2010.09.014
Hutchinson, M., & Reid, J. (2011). In the eyes of the Dunedin public, what constitutes professionalism in medicine? Journal of
Primary Health Care, 3(1), 10-15.
Jaye, C., & Fitzgerald, R. (2012). The embodied liminalities of occupational overuse syndrome. Medical Anthropology
Quarterly, 26(2), 201-220. doi: 10.1111/j.1548-1387.2012.01201.x
Jaye, C., & Fitzgerald, R. (2011). Embodying occupational overuse syndrome. Health, 15(4), 385-400. doi:
10.1177/1363459310376298
Jaye, C., & Fitzgerald, R. (2011). Occupational overuse syndrome: Moral ambiguities of New Zealand health professionals.
Qualitative Health Research, 22(6), 1400-1412. doi: 10.1177/1049732311405998
Lawrenson, R. A., Nixon, G., & Steed, R. H. (2011). The rural hospital doctors workforce in New Zealand. Rural & Remote
Health, 11(2), 1588.
Lloyd, T., Blattner, K., & Nixon, G. (2011). Transfers from rural hospitals in New Zealand. New Zealand Medical Journal,
124(1328). Retrieved from http://journal.nzma.org.nz/journal/124-1328/4509/content.pdf.
McKechnie, R., MacLeod, R., & Jaye, C. (2011). The use of nurses in community palliative care. Home Healthcare Nurse, 29(7),
408-415. doi: 10.1097/NHH.0b013e31821b74ae
Nixon, G., Blattner, K., Dawson, J., Dovey, S., Black, M. A., Wilkins, G., Dunn, A. C., McLellan, A. D. (2011). Streptokinase
antibodies in patients presenting with acute coronary syndrome in three rural New Zealand populations. Journal of
Clinical Pathology, 64, 426-429. doi: 10.1136/jcp.2010.085837
Paterson, H., Kenrick, K., & Wilson, D. (2012). Teaching the Y generation obstetrics and gynaecology skills: A survey of
medical students’ thoughts on a new program. Australian & New Zealand Journal of Obstetrics & Gynaecology, 52(2), 151155. doi: 10.1111/j.1479-828X.2012.01415.x
Ranta, A. (2012). Stroke thrombolysis in New Zealand: A national audit. International Journal of Stroke, 7(Suppl. s1), 35. doi:
10.1111/j.1747-4930.2012.00907.x
Rennie, S. C., van Rij, A. M., Jaye, C., & Hall, K. H. (2011). Defining decision making: A qualitative study of international experts’
views on surgical trainee decision making. World Journal of Surgery, 35(6), 1214-1220. doi: 10.1007/s00268-011-1089-4
Rudland, J., Tordoff, R., Reid, J., & Farry, P. (2011). The clinical skills experience of rural immersion medical students
and traditional hospital placement students: A student perspective. Medical Teacher, 33(8), e435-e439. doi:
10.3109/0142159X.2011.586745
Sherpa, T. W., Sherpa, K. T., Nixon, G., Heydon, J., Heydon, E., & Dovey, S. (2012). The prevalence of Helicobacter pylori
infection in Sherpa residents of the Upper Khumbu, an isolated community in eastern Nepal. New Zealand Medical
Journal, 125(1365). Retrieved from http://journal.nzma.org.nz/journal/125-1365/5429/content.pdf.
Tomlin, A., Dovey, S., Gauld, R., & Tilyard, M. (2011). Better use of primary care laboratory services following interventions
to ‘market’ clinical guidelines in New Zealand: A controlled before-and-after study. BMJ Quality & Safety, 20(3), 282-290.
doi: 10.1136/bmjqs.2010.048124
Tomlin, A., Reith, D., Dovey, S., & Tilyard, M. (2012). Methods for retrospective detection of drug safety signals and adverse
events in electronic general practice records. Drug Safety, 35(9), 733-743. doi: 10.2165/11631970-000000000-00000
Upsdell, M., & Jaye, C. (2011). Engaging with complementary and alternative medicine in general practice. Journal of Primary
Health Care, 3(1), 29-34.
Wallis, K. (2012). ‘Woe is me!’: New Zealand’s non-punitive regulatory environment. Journal of Primary Health Care, 4(1), 73-76.
Wallis, K., & Dovey, S. (2011). No-fault compensation for treatment injury in New Zealand: Identifying threats to patient
safety in primary care. BMJ Quality & Safety, 20(7), 587-591. doi: 10.1136/bmjqs.2010.047696
Wallis, K., & Dovey, S. (2011). Assessing patient safety culture in New Zealand primary care: A pilot study using a modified
Manchester Patient Safety Framework in Dunedin general practices. Journal of Primary Health Care, 3(1), 35-40.
Warren, B., Dovey, S., & Griffin, F. (2011). The evidence behind more than a decade of policy recommending influenza
vaccination for young New Zealanders with long term medical conditions. Kai Tiaki Nursing Research, 2(1), 27-32.
Wilkinson, T. J., Tweed, M. J., Egan, T. G., Ali, A. N., McKenzie, J. M., Moore, M., & Rudland, J. R. (2011). Joining the dots:
Conditional pass and programmatic assessment enhances recognition of problems with professionalism and factors
hampering student progress. BMC Medical Education, 11, 29. doi: 10.1186/1472-6920-11-29
161
RESEARCH REPORT 2011/2012
Williamson, M. I., Wilson, R. A., McKechnie, R., & Ross, J. (2012). Does the positive influence of an undergraduate rural
placement persist into postgraduate years? Rural & Remote Health, 12(2). Retrieved from http://www.rrh.org.au/articles/
subviewnew.asp?ArticleID=2011.
Journal - Research Other
Dovey, S. M., Loh, L. W., & Cunningham, W. K. (2011). Leveraging information from New Zealand statistical data: A first step
to wisdom in transforming unmet need for general practice services [Editorial]. New Zealand Medical Journal, 124(1334).
Retrieved from http://journal.nzma.org.nz/journal/124-1334/4665/content.pdf.
Funnell, M., & Ranta, A. (2012). Vagal nerve stimulation in New Zealand: Improvement of seizure control following the
implantation of a vagal nerve stimulator [Letter]. New Zealand Medical Journal, 125(1361). Retrieved from http://journal.
nzma.org.nz/journal/125-1361/5333/content.pdf.
Hill, A. G., Jaye, C., & Egan, T. (2011). Communities of clinical practice: Understanding how to optimize medical student
experience on a surgical rotation [Perspective]. ANZ Journal of Surgery, 81(10), 661-662. doi: 10.1111/j.14452197.2011.05776.x
Reid, J. (2012). Investment in primary care: Is it worthwhile? [Editorial]. New Zealand Medical Journal, 125(1352). Retrieved
from http://journal.nzma.org.nz/journal/125-1352/5128/content.pdf.
Reid, J. (2012). The health of Pacific peoples in New Zealand [Editorial]. New Zealand Medical Journal, 125(1364). Retrieved
from http://journal.nzma.org.nz/journal/125-1364/5410/content.pdf.
Ross, J., & Kenrick, K. (2011). Continuity of care in New Zealand primary health services [Editorial]. New Zealand Medical
Journal, 124(1329). Retrieved from http://journal.nzma.org.nz/journal/124-1329/4540/content.pdf.
Sweet, G. S., & Wilson, H. J. (2011). A patient’s experience of ward rounds [Reflective practice]. Patient Education &
Counseling, 84(2), 150-151. doi: 10.1016/j.pec.2010.08.016
Journal - Professional & Other Non-Research Articles
Paterson, H., Klemp, D., Folland, C., & Briggs, M. (2012). Electronic maternity facility bookings. Health Care & Informatics
Review Online, 16(1), 8-11.
Reid, J. (2011). [Review of book John Murtagh’s General Practice (5th edition)]. New Zealand Medical Journal, 124(1341).
Retrieved from http://journal.nzma.org.nz/journal/124-1341/4848/content.pdf.
Dunedin School of Medicine
Medicine
Chapter in Book - Research
Cutfield, N. J., & Bronstein, A. M. (2011). Vestibular and related oculomotor disorders. In A. N. Nicholson (Ed.), The
neurosciences and the practice of aviation medicine (pp. 395-419). Farnham, UK: Ashgate.
Hammond-Tooke, G. D., Sebastian, A., Oliver, J., Fulton, J., Watts, R., & Franz, E. E. (2011). Functional imaging of psychogenic
and feigned weakness. In M. Hallet, A. E. Lang, J. Jankovic, S. Fahn, P. W. Halligan, V. Voon & C. R. Cloninger (Eds.),
Psychogenic movement disorders and other conversion disorders (pp. 180-183). Cambridge University Press.
Hesketh, K., Campbell, K., & Taylor, R. (2011). Epidemiology of obesity in children and adolescents in Australia, New Zealand
and the Pacific Region. In L. A. Moreno, I. Pigeot, & W. Ahrens (Eds.), Epidemiology of obesity in children and adolescents:
Prevalence and etiology (pp. 111-125). New York: Springer. doi: 10.1007/978-1-4419-6039-9_7
Mountjoy, M., & Gerrard, D. (2011). Preserving and promoting health in the aquatic athlete. In L. Seifert, D. Chollet & I.
Mujika (Eds.), World book of swimming: From science to performance (pp. 499-511). New York: Nova Science.
Olin, A.-C., & Taylor, D. R. (2011). Exhaled nitric oxide: Towards normal values. In S. Loukides, K. Kostikas & P. J. Barnes
(Eds.), Non-invasive assessment of airways inflammation in Asthma & COPD (pp. 41-58). Athens, Greece: PMP.
Thomson, W. M., Ikebe, K., Tordoff, J. M., & Campbell, A. J. (2011). Dry mouth and medications. In M. I. MacEntee (Ed.),
Oral healthcare and the frail elderly: A clinical perspective (pp. 51-72). Ames, IA: Blackwell.
van Gelderen, F. (2012). Dermatomyositis. In A. Zaher (Ed.), Neuromuscular Disorders. InTech. doi: 10.5772/1668
Wong, C.-K., & White, H. D. (2012). Fibrinolysis for acute myocardial infarction. In S. Mukherjee, S. Nasim, & R. Srivastava
(Eds.), Management of acute myocardial infarction (pp. 17-34). Haryana, India: Elsevier.
Wong, C.-K., & White, H. D. (2012). Electrocardiography in acute coronary syndromes. In H.D. White (Ed.), Advances in acute
coronary syndrome management (pp. 110-122). London: Future Medicine. doi: 10.2217/EBO.11.326
Journal - Research Article
Abdul-Rahman, A. M., Molteno, A. C. B., & Bevin, T. H. (2011). The epidemiology of giant cell arteritis in Otago, New
Zealand: A 9-year analysis. New Zealand Medical Journal, 124(1329). Retrieved from http://journal.nzma.org.nz/
journal/124-1329/4533/content.pdf.
Amer, M., Hubert, G., Sullivan, S. J., Herbison, P., Franz, E. A., & Hammond-Tooke, G. D. (2012). Reliability and diagnostic
characteristics of clinical tests of upper limb motor function. Journal of Clinical Neuroscience, 19(9), 1246-1251. doi:
10.1016/j.jocn.2011.12.007
Ang, W. C., Doyle, T., & Stringer, M. D. (2012). Left-sided and duplicate inferior vena cava: A case series and review. Clinical
Anatomy. Advance online publication. doi: 10.1002/ca.22090
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Baigent, C., Landray, M. J., Reith, C., Emberson, J., Wheeler, D. C., Tomson, C., … Walker, R., … on behalf of the SHARP
Investigators. (2011). The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic
kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial. Lancet, 377(9784), 21812192. doi: 10.1016/S0140-6736(11)60739-3
Bird, S. D., Legge, M., & Walker, R. J. (2011). Thiols stabilize cobblestone morphology of cultured mesothelial cells. Cell Biology
International, 35(8), 857-867. doi: 10.1042/CBI20100593
Bocock, C., Reeder, A. I., Perez, D., & Trevena, J. (2011). Beliefs of New Zealand doctors about integrative medicine for cancer
treatment. Integrative Cancer Therapies, 10(3), 280-288. doi: 10.1177/1534735411403476
Braatvedt, G. D., Cundy, T., Crooke, M., Florkowski, C., Mann, J. I., Lunt, H., … Drury, P. L. (2012). Understanding the new
HbA1c units for the diagnosis of Type 2 diabetes [Review article]. New Zealand Medical Journal, 125(1362). Retrieved
from http://journal.nzma.org.nz/journal/125-1362/5345/content.pdf.
Brian, G., du Toit, R., Ramke, J., & Szetu, J. (2011). Population-based study of self-reported ocular trauma in Fiji. Clinical &
Experimental Ophthalmology, 39(5), 441-448. doi: 10.1111/j.1442-9071.2010.02476.x
Brian, G., Maher, L., Ramke, J., & Palagyi, A. (2012). Eye care in Fiji: A population-based study of use and barriers. Ophthalmic
Epidemiology, 19(2), 43-51. doi: 10.3109/09286586.2011.628135
Brian, G., Pearce, M. G., & Ramke, J. (2011). Refractive error and presbyopia among adults in Fiji. Ophthalmic Epidemiology,
18(2), 75-82. doi: 10.3109/09286586.2010.551576
Brian, G., Ramke, J., Maher, L., Page, A., Fischer-Harder, K., & Sikivou, B. (2011). Body mass index among Melanesian
and Indian Fijians aged ≥ 40 years living in Fiji. Asia-Pacific Journal of Public Health, 23(1), 34-43. doi:
10.1177/1010539510390665
Brian, G., Ramke, J., Page, A., Maher, L., Szetu, J., & Qalo Qoqonokana, M. (2011). The association of diabetes and BMI
among Melanesian and Indian Fijians aged ≥40 years. British Journal of Nutrition, 105(10), 1539-1545. doi: 10.1017/
s0007114510005258
Brian, G., Ramke, J., Szetu, J., & Qalo Qoqonokana, M. (2011). Cataract and its surgery in Fiji. Clinical & Experimental
Ophthalmology, 39(5), 449-455. doi: 10.1111/j.1442-9071.2010.02477.x
Brian, G., Sikivou, B., Fischer-Harder, K., Szetu, J., Qoqonokana, M. Q., & Ramke, J. (2011). Diabetic eye disease among adults
in Fiji with previously undiagnosed diabetes. Clinical & Experimental Ophthalmology, 39(7), 682-690. doi: 10.1111/j.14429071.2011.02533.x
Brian, G., Tousignant, B., Venn, B. J., McKay, R., & Gould, C. (2011). Serum retinol and xerophthalmia among a prison
population in Papua New Guinea. Ophthalmic Epidemiology, 18(6), 288-294. doi: 10.3109/09286586.2011.615450
Brooking, L. A., Williams, S. M., & Mann, J. I. (2012). Effects of macronutrient composition of the diet on body fat in
indigenous people at high risk of type 2 diabetes. Diabetes Research & Clinical Practice, 96(1), 40-46. doi: 10.1016/j.
diabres.2011.11.021
Cameron, C. M., Coppell, K. J., Fletcher, D. J., & Sharples, K. J. (2012). Capture-recapture using multiple data sources:
Estimating the prevalence of diabetes. Australian & New Zealand Journal of Public Health, 36(3), 223-228. doi:
10.1111/j.1753-6405.2012.00868.x
Cameron, I. D., Gillespie, L. D., Robertson, M. C., Murray, G. R., Hill, K. D., Cumming, R. G., & Kerse, N. (2012). Interventions
for preventing falls in older people in care facilities and hospitals (Review). Cochrane Database of Systematic Reviews, 12,
CD005465. doi: 10.1002/14651858.CD005465.pub3
Cameron, S. L., Heath, A.-L. M., & Taylor, R. W. (2012). Healthcare professionals’ and mothers’ knowledge of, attitudes to and
experiences with, Baby-Led Weaning: A content analysis study. BMJ Open, 2, e001542. doi: 10.1136/bmjopen-2012-001542
Cameron, S. L., Heath, A.-L. M., & Taylor, R. W. (2012). How feasible is baby-led weaning as an approach to infant feeding? A
review of the evidence. Nutrients, 4(11), 1575-1609. doi: 10.3390/nu4111575
Carrick-Ranson, G., Doughty, R. N., Whalley, G. A., Walsh, H. J., Gamble, G. D., & Baldi, J. C. (2012). The larger exercise stroke
volume in endurance-trained men does not result from increased left ventricular early or late inflow or tissue velocities.
Acta Physiologica, 205(4), 520-531. doi: 10.1111/j.1748-1716.2012.02430.x
Carter, P. J., Taylor, B. J., Williams, S. M., & Taylor, R. W. (2011). Longitudinal analysis of sleep in relation to BMI and body fat
in children: The FLAME study. BMJ, 342, d2712. doi: 10.1136/bmj.d2712
Chen-Xu, M., Topless, R., McKinney, C., Merriman, M. E., Phipps-Green, A., Dalbeth, N., … Harrison, A. A., Highton, J., …
van Rij, A., Jones, G. T., … Stamp, L. K., … Merriman, T. R. (2012). Replication of association of the interleukin 23
receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets. Annals of the Rheumatic Diseases, 71(1),
155-157. doi: 10.1136/annrheumdis-2011-200591
Chong, Y. H., Campbell, A. J., Farrand, S., & McLennan, I. S. (2012). Anti-Müllerian hormone level in older women: Detection
of granulosa cell tumor recurrence. International Journal of Gynecological Cancer, 22(9), 1497-1499. doi: 10.1097/
IGC.0b013e318270ac69
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2012). Plasma active
matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International
Journal of Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.03.147
Coffey, S., Nadarasa, K., Pan, A., van der Linden, A., Chu, J., & Schultz, M. (2012). The increasing incidence of Streptococcus
bovis endocarditis and bacteraemia: A case series from 1997 to 2010. International Journal of Cardiology, (0). Advance
online publication. doi: 10.1016/j.ijcard.2012.06.031
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Coppell, K. J., Anderson, K., Williams, S. M., Lamb, C., Farmer, V. L., & Mann, J. I. (2011). The quality of diabetes care: A
comparison between patients enrolled and not enrolled on a regional diabetes register. Primary Care Diabetes, 5(2), 131137. doi: 10.1016/j.pcd.2010.10.005
Coppell, K. J., Lee, J. E. H., Williams, S. M., & Mann, J. I. (2011). Progression of glycaemia and cardiovascular risk factors in
patients of different age groups with new type 2 diabetes over 5 years of follow-up in a diabetes quality improvement
initiative. Diabetes Research & Clinical Practice, 93(3), 357-362. doi: 10.1016/j.diabres.2011.04.021
Cutfield, N. J., Cousins, S., Seemungal, B. M., Gresty, M. A., & Bronstein, A. M. (2011). Vestibular perceptual thresholds to
angular rotation in acute unilateral vestibular paresis and with galvanic stimulation. Annals of the New York Academy of
Sciences, 1233, 256-262. doi: 10.1111/j.1749-6632.2011.06159.x
Davis, J. C., Liu-Ambrose, T., Khan, K. M., Robertson, M. C., & Marra, C. A. (2012). SF-6D and EQ-5D result in widely
divergent incremental cost-effectiveness ratios in a clinical trial of older women: Implications for health policy decisions.
Osteoporosis International, 23(7), 1849-1857. doi: 10.1007/s00198-011-1770-3
Davis, J. C., Marra, C. A., Robertson, M. C., Khan, K. M., Najafzadeh, M., Ashe, M. C., & Liu-Ambrose, T. (2011). Economic
evaluation of dose-response resistance training in older women: A cost-effectiveness and cost-utility analysis. Osteoporosis
International, 22(5), 1355-1366. doi: 10.1007/s00198-010-1356-5
Davis, J. C., Marra, C. A., Robertson, M. C., Najafzadeh, M., & Liu-Ambrose, T. (2011). Sustained economic benefits of
resistance training in community-dwelling senior women. Journal of the American Geriatrics Society, 59(7), 1232-1237. doi:
10.1111/j.1532-5415.2011.03474.x
Davis, J. C., Robertson, M. C., Comans, T., & Scuffham, P. A. (2011). Guidelines for conducting and reporting economic
evaluation of fall prevention strategies. Osteoporosis International, 22(9), 2449-2459. doi: 10.1007/s00198-010-1482-0
Davis, T. M. E., Ting, R. D., Best, J. D., Donoghoe, M. W., Drury, P. L., Sullivan, D. R., … on behalf of the FIELD Study
Investigators, including Manning, P. (2011). Effects of fenofibrate on renal function in patients with type 2 diabetes
mellitus: The fenofibrate intervention and event lowering in diabetes (FIELD) study. Diabetologia, 54(2), 280-290. doi:
10.1007/s00125-010-1951-1.
Dempster, A. G., Molteno, A. C. B., Bevin, T. H., & Thompson, A. M. (2011). Otago Glaucoma Surgery Outcome Study:
Electron microscopy of capsules around Molteno implants. Investigative Ophthalmology & Visual Science, 52(11), 83008309. doi: 10.1167/iovs.11-7772
Docherty, P. D., Chase, J. G., Lotz, T. F., Hann, C. E., Shaw, G. M., Berkeley, J. E., TeMorenga, L., Mann, J. I., McAuley, K.
(2011). Independent cohort cross-validation of the real-time DISTq estimation of insulin sensitivity. Computer Methods &
Programs in Biomedicine, 102(2), 94-104. doi: 10.1016/j.cmpb.2010.08.002
Donnelly, J., Cowan, D. C., Yeoman, D. J., Lucas, S. J. E., Herbison, G. P., Thomas, K. N., Ainslie, P. N., Taylor, D. R. (2011).
Exhaled nitric oxide and pulmonary artery pressures during graded ascent to high altitude. Respiratory Physiology &
Neurobiology, 177(3), 213-217. doi: 10.1016/j.resp.2011.04.008
Durst, R., Avelar, E., McCarty, D., Poh, K.-K., Friera, L. F., Llano, M. F., Chu, J., … Picard, M. H. (2011). Outcome and
improvement predictors of mitral regurgitation after transcatheter aortic valve implantation. Journal of Heart Valve
Disease, 20(3), 272-281.
Dweik, R. A., Boggs, P. B., Erzurum, S. C., Irvin, C. G., Leigh, M. W., Lundberg, J. O., … Taylor, D. R., on behalf of the
American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications.
(2011). An Official ATS Clinical Practice Guideline: Interpretation of exhaled nitric oxide levels (FENO) for clinical
applications. American Journal of Respiratory & Critical Care Medicine, 184(5), 602-615. doi: 10.1164/rccm.9120-11ST
Endre, Z. H., Pickering, J. W., & Walker, R. J. (2011). Clearance and beyond: The complementary roles of GFR measurement
and injury biomarkers in acute kidney injury (AKI). American Journal of Physiology: Renal Physiology, 301(4), F697-F707.
doi: 10.1152/ajprenal.00448.2010
Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M.,
Henderson, S. J., Nejat, M., Schollum, J. B. W., George, P. M. (2011). Improved performance of urinary biomarkers of acute
kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79,
1119-1130. doi: 10.1038/ki.2010.555
International Multiple Sclerosis Genetics Consortium, and the Wellcome Trust Case Control Consortium 2, including Mason,
D., & Mottershead, J. (2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature, 476, 214-219. doi: 10.1038/nature10251
Gillespie, L. D., Robertson, M. C., Gillespie, W. J., Sherrington, C., Gates, S., Clemson, L. M., & Lamb, S. E. (2012).
Interventions for preventing falls in older people living in the community (Review). Cochrane Database of Systematic
Reviews, 9, CD007146. doi: 10.1002/14651858.CD007146.pub3
Gusso, S., Pinto, T. E., Baldi, J. C., Robinson, E., Cutfield, W. S., & Hofman, P. L. (2012). Diastolic function is reduced in
adolescents with type 1 diabetes in response to exercise. Diabetes Care, 35(10), 2089-2094. doi: 10.2337/dc11-2331
Ha, J.-H., & Wong, C.-K. (2011). Pharmacologic treatment of depression in patients with myocardial infarction. Journal of
Geriatric Cardiology, 8(2), 121-126. doi: 10.3724/SP.J.1263.2011.00121
Hancox, R. J., Cowan, D. C., Aldridge, R. E., Cowan, J. O., Palmay, R., Williamson, A., Town, G. I., Taylor, D. R. (2012). Asthma
phenotypes: Consistency of classification using induced sputum. Respirology, 17(3), 461-466. doi: 10.1111/j.14401843.2011.02113.x
Haszard, J., Williams, S. M., Dawson, A. M., Skidmore, P. M. L., & Taylor, R. W. (2012). Factor analysis of the Comprehensive
Feeding Practices Questionnaire in a large sample of children. Appetite. Advance online publication. doi: 10.1016/j.
appet.2012.11.017
164
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Hazlett, J., Stamp, L. K., Merriman, T., Highton, J., & Hessian, P. A. (2011). IL-23R rs11209026 polymorphism modulates IL17A expression in patients with rheumatoid arthritis. Genes & Immunity. doi: 10.1038/gene.2011.80
Hobbs, J. K., Shepherd, C., Saul, D. J., Demetras, N. J., Haaning, S., Monk, C. R., … Arcus, V. L. (2012). On the origin and
evolution of thermophily: Reconstruction of functional precambrian enzymes from ancestors of Bacillus. Molecular
Biology & Evolution, 29(2), 825-835. doi: 10.1093/molbev/msr253
Hollis-Moffatt, J. E., Gow, P. J., Harrison, A. A., Highton, J., Jones, P. B. B., Stamp, L. K., … Merriman, T. R. (2011). The
SLC2A9 nonsynonymous Arg265His variant and gout: Evidence for a population-specific effect on severity. Arthritis
Research & Therapy, 13(3), R85. doi: 10.1186/ar3356
Hollis-Moffatt, J. E., Phipps-Green, A. J., Chapman, B., Jones, G. T., van Rij, A., Gow, P. J., Harrison, A. A., Highton, J., …
Stamp, L. K., … Merriman, T. R. (2012). The renal urate transporter SLC17A1 locus: Confirmation of association with
gout. Arthritis Research & Therapy, 14(2), R92. doi: 10.1186/ar3816
Hopkins, S. A., Baldi, J. C., Cutfield, W. S., McCowan, L., & Hofman, P. L. (2011). Effects of exercise training on maternal
hormonal changes in pregnancy. Clinical Endocrinology, 74(4), 495-500. doi: 10.1111/j.1365-2265.2010.03964.x
Hudson, B., Zarifeh, A., Young, L., & Wells, J. E. (2012). Patients’ expectations of screening and preventive treatments. Annals of
Family Medicine, 10(6), 495-502. doi: 10.1370/afm.1407
Jordan, S. R., Stevanovic, V. R., Herbison, P., Dockerty, J., & Highton, J. (2011). Methotrexate pneumonitis in rheumatoid
arthritis: Increased prevalence with increasing latitude: An epidemiological study of trends in New Zealand. Journal of
Clinical Rheumatology, 17(7), 356-357.
Kazantseva, M., Highton, J., Stamp, L. K., & Hessian, P. A. (2012). Dendritic cells provide a potential link between smoking and
inflammation in rheumatoid arthritis. Arthritis Research & Therapy, 14, R208. doi: 10.1186/ar4046
Kieser, D. C., Gwynne-Jones, D., & Dreyer, S. (2011). Displaced tibial intercondylar eminence fractures. Journal of Orthopaedic
Surgery, 19(3), 292-296.
Kini, G. P., Murray, I., Champion-Young, J., Lau, M., Katta, V., Thorn, M., & Schultz, M. P. (2012). Cap polyposis mistaken
for Crohn’s disease: Case report and review of literature. Journal of Crohn’s & Colitis. Advance online publication. doi:
10.1016/j.crohns.2012.06.005
Korell, J., Vos, F. E., Coulter, C. V., Schollum, J. B., Walker, R. J., & Duffull, S. B. (2011). Modeling red blood cell survival data.
Journal of Pharmacokinetics & Pharmacodynamics, 38(6), 797-801. doi: 10.1007/s10928-011-9220-6
Kostikas, K., Papaioannou, A. I., Tanou, K., Giouleka, P., Koutsokera, A., Minas, M., … Taylor, D. R., Loukides, S. (2011).
Exhaled NO and exhaled breath condensate pH in the evaluation of asthma control. Respiratory Medicine, 105(4), 526-532.
doi: 10.1016/j.rmed.2010.10.015
Krebs, J. D., Elley, C. R., Parry-Strong, A., Lunt, H., Drury, P. L., Bell, D. A., … Mann, J. I. (2012). The Diabetes Excess Weight
Loss (DEWL) trial: A randomised controlled trial of high-protein versus high-carbohydrate diets over 2 years in type 2
diabetes. Diabetologia, 55, 905-914. doi: 10.1007/s00125-012-2461-0
Kuo, H.-K., Kuo, M.-T., Tiong, I.-S., Wu, P.-C., Chen, Y.-J., & Chen, C.-H. (2011). Visual acuity as measured with Landolt C
chart and Early Treatment of Diabetic Retinopathy Study (ETDRS) chart. Graefe’s Archive for Clinical & Experimental
Ophthalmology, 249(4), 601-605. doi: 10.1007/s00417-010-1461-3
Lamb, S. E., Becker, C., Gillespie, L. D., Smith, J. L., Finnegan, S., Potter, R., … Taxonomy Investigators. (2011). Reporting of
complex interventions in clinical trials: Development of a taxonomy to classify and describe fall-prevention interventions.
Trials, 12, 125. doi: 10.1186/1745-6215-12-125
Langley, J., Samaranayaka, A., Davie, G., & Campbell, A. J. (2011). Age, cohort and period effects on hip fracture incidence:
Analysis and predictions from New Zealand data 1974-2007. Osteoporosis International, 22(1), 105-111. doi: 10.1007/
s00198-010-1205-6
Lee, H., Sullivan, S. J., & Schneiders, A. G. (2012). The use of the dual-task paradigm in detecting gait performance deficits
following a sports-related concussion: A systematic review and meta-analysis. Journal of Science & Medicine in Sport.
Advance online publication. doi: 10.1016/j.jsams.2012.03.013
Leon de la Barra, S., Smith, A. D., Cowan, J. O., Herbison, G. P., & Taylor, D. R. (2011). Predicted versus absolute values
in the application of exhaled nitric oxide measurements. Respiratory Medicine, 105(11), 1629-1634. doi: 10.1016/j.
rmed.2011.06.001
Li, P. K.-T., Cheung, W. L., Lui, S. L., Blagg, C., Cass, A., Hooi, L. S., … Walker, R., … Yu, A. W.-Y. (2011). Increasing homebased dialysis therapies to tackle dialysis burden around the world: A position statement on dialysis economics from the
2nd Congress of the International Society for Hemodialysis. Hemodialysis International, 15(1), 10-14. doi: 10.1111/j.15424758.2010.00512.x
Ludeke, M., Puni, R., Cook, L., Pasene, M., Abel, G., & Sopoaga, F. (2012). Access to general practice for Pacific peoples: A place
for cultural competency. Journal of Primary Health Care, 4(2), 123-130.
Manning, P. J., De Jong, S. A., Ryalls, A. R., & Sutherland, W. H. F. (2012). Paraoxonase 1 activity in chylomicrons and VLDL:
The effect of type 2 diabetes and meals rich in saturated fat and oleic acid. Lipids, 47(3), 259-267. doi: 10.1007/s11745011-3640-3
Manning, P. J., Sutherland, W. H. F., Williams, S. M., Walker, R. J., Berry, E. A., De Jong, S. A., & Ryalls, A. R. (2012). The effect
of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. Nutrition, Metabolism & Cardiovascular
Diseases. Advance online publication. doi: 10.1016/j.numecd.2011.11.006
Marsden, R., & Osborne, H. R. (2011). Diagnosis and management of lateral elbow pain in the elite athlete. New Zealand
Journal of Sports Medicine, 38(1), 32-34.
165
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McAuley, K. A., Berkeley, J. E., Docherty, P. D., Lotz, T. F., Te Morenga, L. A., Shaw, G. M., Williams, S. M., … Mann, J. I. (2011).
The dynamic insulin sensitivity and secretion test: A novel measure of insulin sensitivity. Metabolism, 60(12), 1748-1756.
doi: 10.1016/j.metabol.2011.05.009
McKelvey, K. J., Highton, J., & Hessian, P. A. (2011). Cell-specific expression of TLR9 isoforms in inflammation. Journal of
Autoimmunity, 36(1), 76-86. doi: 10.1016/j.jaut.2010.11.001
McLean, R., Hoek, J., & Hedderley, D. (2012). Effects of alternative label formats on choice of high- and low-sodium products
in a New Zealand population sample. Public Health Nutrition, 15(5), 783-791. doi: 10.1017/s1368980011003508
McLean, R. M., Mann, J. I., & Hoek, J. (2011). World Salt Awareness Week: More action needed in New Zealand [Viewpoint].
New Zealand Medical Journal, 124(1332). Retrieved from http://journal.nzma.org.nz/journal/124-1332/4607/content.pdf.
Meredith-Jones, K., Waters, D., Legge, M., & Jones, L. (2011). Upright water-based exercise to improve cardiovascular
and metabolic health: A qualitative review. Complementary Therapies in Medicine, 19(2), 93-103. doi: 10.1016/j.
ctim.2011.02.002
Miller, J. C., Thomson, C. D., Williams, S. M., van Havre, N., Wilkins, G. T., Morison, I. M., Ludgate, J. L., Skeaff, C. M. (2012).
Influence of the glutathione peroxidase 1 Pro200Leu polymorphism on the response of glutathione peroxidase activity
to selenium supplementation: A randomized controlled trial. American Journal of Clinical Nutrition, 96, 923-931. doi:
10.3945/ajcn.112.043125
Mirjalili, S. A., Hale, S. J. M., Buckenham, T., Wilson, B., & Stringer, M. D. (2012). A reappraisal of adult thoracic surface
anatomy. Clinical Anatomy, 25(7), 827-834. doi: 10.1002/ca.22091
Mirjalili, S. A., McFadden, S. L., Buckenham, T., Wilson, B., & Stringer, M. D. (2012). Anatomical planes: Are we teaching
accurate surface anatomy? Clinical Anatomy, 25(7), 819-826. doi: 10.1002/ca.22104
Molteno, A. C. B., Bevin, T. H., Herbison, P., & Husni, M. A. (2011). Long-term results of primary trabeculectomies and
Molteno implants for primary open-angle glaucoma. Archives of Ophthalmology, 129(11), 1444-1450. doi: 10.1001/
archophthalmol.2011.221
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011).
Cardiorespiratory and cerebrovascular responses to head-up tilt II: Influence of age, training status and acute exercise.
Experimental Gerontology, 46(1), 1-8. doi: 10.1016/j.exger.2010.06.004
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011).
Cardiorespiratory and cerebrovascular responses to head-up tilt I: Influence of age and training status. Experimental
Gerontology, 46(1), 9-17. doi: 10.1016/j.exger.2010.06.005
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011). Syncope is
unrelated to supine and postural hypotension following prolonged exercise. European Journal of Applied Physiology &
Occupational Physiology, 111(3), 469-476. doi: 10.1007/s00421-010-1671-8
Murrell, C. J., Cotter, J. D., Thomas, K. N., Lucas, S. J. E., Williams, M. J. A., & Ainslie, P. N. (2012). Cerebral blood flow and
cerebrovascular reactivity at rest and during sub-maximal exercise: Effect of age and 12-week exercise training. Age.
Advance online publication. doi: 10.1007/s11357-012-9414-x
Nadarasa, K., Robertson, M. C., Wong, C.-K., Green, B. K. W., Chen, V. H. T., Wilkins, G. T., & Williams, M. J. A. (2012). Rapid
cycle change to predominantly radial access coronary angiography and percutaneous coronary intervention: Effect on
vascular access site complications. Catheterization & Cardiovascular Interventions, 79(4), 589-594. doi: 10.1002/ccd.23120
Nadarasa, K., & Williams, M. J. A. (2012). Single high oral dose amiodarone for cardioversion of recent onset atrial fibrillation.
Heart, Lung & Circulation, 21(8), 444-448. doi: 10.1016/j.hlc.2012.03.015
Nejat, M., Pickering, J. W., Devarajan, P., Bonventre, J. V., Edelstein, C. L., Walker, R. J., & Endre, Z. H. (2012). Some
biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney International, 81, 1254-1262. doi:
10.1038/ki.2012.23
Nixon, G., Blattner, K., Dawson, J., Dovey, S., Black, M. A., Wilkins, G., Dunn, A. C., McLellan, A. D. (2011). Streptokinase
antibodies in patients presenting with acute coronary syndrome in three rural New Zealand populations. Journal of
Clinical Pathology, 64, 426-429. doi: 10.1136/jcp.2010.085837
Nukada, H., McMorran, P. D., Baba, M., Ogasawara, S., & Yagihashi, S. (2011). Increased susceptibility to ischemia and
macrophage activation in STZ-diabetic rat nerve. Brain Research, 1373, 172-182. doi: 10.1016/j.brainres.2010.11.084
Osborne, H. R., Quinlan, J. F., & Allison, G. T. (2012). Hip abduction weakness in elite junior footballers is common but easy
to correct quickly: A prospective sports team cohort based study. Sports Medicine, Arthroscopy, Rehabilitation, Therapy &
Technology, 4(37). doi: 10.1186/1758-2555-4-37
Pan, A., Schlup, M., Lubcke, R., Chou, A., & Schultz, M. (2012). The role of aspirin in post-polypectomy bleeding: A
retrospective survey. BMC Gastroenterology, 12, 138. doi: 10.1186/1471-230X-12-138
Pan, A., Schlup, M., Lubcke, R., & Schultz, M. (2011). Fulminant ulcerative colitis despite maximal immunosuppression
following liver transplantation: A case report and literature review. Journal of Crohn’s & Colitis, 5(5), 465-468. doi:
10.1016/j.crohns.2011.04.011
Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better
than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391
Pinto, D., Robertson, M. C., Hansen, P., & Abbott, J. H. (2012). Cost-effectiveness of nonpharmacologic, nonsurgical
interventions for hip and/or knee osteoarthritis: Systematic review. Value in Health, 15(1), 1-12. doi: 10.1016/j.
jval.2011.09.003
166
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Pinto, D., Robertson, M. C., Hansen, P., & Abbott, J. H. (2011). Good agreement between questionnaire and administrative
databases for health care use and costs in patients with osteoarthritis. BMC Medical Research Methodology, 11, 45. doi:
10.1186/1471-2288-11-45
Pinto, D., Robertson, M. C., Hansen, P., Abbott, J. H., on behalf of the MOA Trial Team. (2011). Economic evaluation within a
factorialdesign randomised controlled trial of exercise, manual therapy, or both interventions for osteoarthritis of the hip
or knee: Study protocol. BMJ Open, 1(1), e000136. doi: 10.1136/bmjopen-2011-000136
Powell, H., Murphy, V. E., Taylor, D. R., Hensley, M. J., McCaffery, K., Giles, W., … Gibson, P. G. (2011). Management of
asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomised controlled
trial. Lancet, 378(9795), 983-990. doi: 10.1016/s0140-6736(11)60971-9
Pullar, J. M., Chisholm, A., & Jackson, C. (2012). Dietary information for colorectal cancer survivors: An unmet need. New
Zealand Medical Journal, 125(1356). Retrieved from http://journal.nzma.org.nz/journal/125-1356/5215/content.pdf.
Ramke, J., & Brian, G. (2012). BMI among Timorese aged ≥40 years. Public Health Nutrition, 15(11), 2118-2123. doi: 10.1017/
s1368980011003491
Ramke, J., Brian, G., Maher, L., Qalo Qoqonokana, M., & Szetu, J. (2012). Prevalence and causes of blindness and low vision
among adults in Fiji. Clinical & Experimental Ophthalmology, 40(5), 490-496. doi: 10.1111/j.1442-9071.2011.02749.x
Ramke, J., Brian, G., Naduvilath, T., Lee, L., & Qalo Qoqonokana, M. (2012). Prevalence and causes of blindness
and low vision revisited after 5 years of eye care in Timor-Leste. Ophthalmic Epidemiology, 19(2), 52-57. doi:
10.3109/09286586.2011.645108
Ramke, J., Brian, G., & Palagyi, A. (2012). Spectacle dispensing in Timor-Leste: Tiered-pricing, cross-subsidization and
financial viability. Ophthalmic Epidemiology, 19(4), 231-235. doi: 10.3109/09286586.2012.680528
Ramke, J., Maher, L., Lee, L., Hobday, K., & Brian, G. (2012). Diabetes and its ocular complications: Awareness among
adults aged 40 years and older in Timor-Leste. Clinical & Experimental Optometry, 95(3), 377-381. doi: 10.1111/j.14440938.2011.00681.x
Richter, K. K., Dempster, A., Tos, A. P. D., Premkumar, R., & Jackson, C. (2011). Challenging differential diagnosis of a wildtype gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational
analysis. New Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4583/
content.pdf.
Robinson, P. C., Merriman, T. R., Herbison, P., & Highton, J. (2012). Hospital admissions associated with gout and their
co-morbidities in New Zealand and England 1999-2009. Rheumatology. Advance online publication. doi: 10.1093/
rheumatology/kes253
Rodrigues, M., Hammond-Tooke, G., Kidd, A., Love, D., Patel, R., Dawkins, H., … Roxburgh, R. (2012). The New
Zealand Neuromuscular Disease Registry. Journal of Clinical Neuroscience. Advance online publication. doi: 10.1016/j.
jocn.2012.04.008
Royds, J. A., Al Nadaf, S., Wiles, A. K., Chen, Y.-J., Ahn, A., Shaw, A., Bowie, S., … Braithwaite, A. W., … Hung, N. A., Slatter, T.
L. (2011). The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism
tumors and is associated with poorer survival. PLoS ONE, 6(10), e26737. doi: 10.1371/journal.pone.0026737
Scaletti, E. R., Luckner, S. R., & Krause, K. L. (2012). Structural features and kinetic characterization of alanine racemase from
Staphylococcus aureus (Mu50). Acta Crystallographica Section D, 68, 82-92. doi: 10.1107/S0907444911050682
Schofield, K. L., Rehrer, N. J., Perry, T. L., Ross, A., Andersen, J. L., & Osborne, H. (2012). Insulin and fiber type in offspring of
T2DM with resistance training and detraining. Medicine & Science in Sports & Exercise. Advance online publication. doi:
10.1249/MSS.0b013e318268008f
Schollum, J. B. W., & Walker, R. J. (2012). Adult urinary tract infection. British Journal of Hospital Medicine, 73(4), 218-223.
Schultz, M., Baranchi, A., Thurston, L., Yu, Y. C., Wang, L., Chen, J., Sapsford, M., Chung, J., Binsadiq, M., Craig, L., Wilkins,
B., McBride, D., Herbison, P. (2011). Consumer demographics and expectations of probiotic therapy in New Zealand:
Results of a large telephone survey. New Zealand Medical Journal, 124(1329). Retrieved from http://journal.nzma.org.nz/
journal/124-1329/4537/content.pdf.
Scott, R., Donoghoe, M., Watts, G. F., O’Brien, R., Pardy, C., Taskinen, M.-R., … Manning, P., … Keech, A. C. (2011). Impact
of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes
assigned to placebo in the FIELD randomised trial. Cardiovascular Diabetology, 10, 102. doi: 10.1186/1475-2840-10-102
Silverman, S. L., Chines, A. A., Kendler, D. L., Kung, A. W. C., Teglbjærg, C. S., Felsenberg, D., … for the Bazedoxifene
Study Group, including Manning, P. (2012). Sustained efficacy and safety of bazedoxifene in preventing fractures in
postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study. Osteoporosis
International, 23(1), 351-363. doi: 10.1007/s00198-011-1691-1
Slade, H., Williams, S. M., Manning, P. J., & Walker, R. J. (2011). High-risk diabetic nephropathy patients: The outcome
of evidence-based clinical practice in an outpatient clinic. Diabetes Research & Clinical Practice, 92(3), 356-360. doi:
10.1016/j.diabres.2011.02.022
Slaughter, R. J., Beasley, D. M. G., Lambie, B. S., Wilkins, G. T., & Schep, L. J. (2012). Poisonous plants in New Zealand: A
review of those that are most commonly enquired about to the National Poisons Centre. New Zealand Medical Journal,
125(1367). Retrieved from http://journal.nzma.org.nz/journal/125-1367/5483/content.pdf.
Sorrenson, B., Suetani, R. J., Bickley, V. M., George, P. M., Williams, M. J. A., Scott, R. S., & McCormick, S. P. A. (2011). An
ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1
mutations. Biochemical & Biophysical Research Communications, 409(3), 400-405. doi: 10.1016/j.bbrc.2011.05.006
167
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Sorrenson, B., Suetani, R. J., Williams, M. J. A., Bickley, V. M., George, P. M., Jones, G. T., & McCormick, S. P. A. (2012).
Functional rescue of mutant ABCA1 proteins by sodium 4-phenylbutyrate. Journal of Lipid Research. Advance online
publication. doi: 10.1194/jlr.M027193
Sosenko, J. M., Mahon, J. L., Rafkin, L., Lachin, J. M., Krause-Steinrauf, H., Krischer, J. P., … and the Diabetes Prevention TrialType 1 and TrialNet Study Groups, including Manning, P. (2011). A comparison of the baseline metabolic profiles between
Diabetes Prevention Trial-Type 1 and TrialNet Natural History study participants. Pediatric Diabetes, 12(2), 85-90. doi:
10.1111/j.1399-5448.2010.00662.x
Sosenko, J. M., Skyler, J. S., Mahon, J., Krischer, J. P., Beam, C. A., Boulware, D. C., … the Type 1 Diabetes TrialNet and
Diabetes Prevention Trial-Type 1 Study Groups, including Manning, P. (2011). Validation of the Diabetes Prevention TrialType 1 risk score in the TrialNet Natural History study. Diabetes Care, 34(8), 1785-1787. doi: 10.2337/dc11-0641
Sosenko, J. M., Skyler, J. S., Palmer, J. P., Krischer, J. P., Cuthbertson, D., Yu, L., … Diabetes Prevention Trial-Type 1, and
Type 1 Diabetes TrialNet Study Groups, including Manning, P. (2011). A longitudinal study of GAD65 and ICA512
autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants.
Diabetes Care, 34(11), 2435-2437. doi: 10.2337/dc11-0981
Stamp, L. K., Hazlett, J., Roberts, R. L., Frampton, C., Highton, J., & Hessian, P. A. (2012). Adenosine receptor expression in
rheumatoid synovium: A basis for methotrexate action. Arthritis Research & Therapy, 14, R138. doi: 10.1186/ar3871
Stebbings, S., Bagheri, N., Perrie, K., Blyth, P., & McDonald, J. (2012). Blended learning and curriculum renewal across three
medical schools: The rheumatology module at the University of Otago. Australasian Journal of Educational Technology,
28(7), 1176-1189.
Stebbings, S., Jenks, K., Treharne, G. J., García, J. A., Schultz, M., Highton, J., & Dudley-Brown, S. (2012). Validation of the
Dudley Inflammatory Bowel Symptom Questionnaire for the assessment of bowel symptoms in axial SpA: Prevalence
of clinically relevant bowel symptoms and association with disease activity. Rheumatology, 51(5), 858-865. doi: 10.1093/
rheumatology/ker359
Suetani, R. J., Sorrenson, B., Tyndall, J. D. A., Williams, M. J. A., & McCormick, S. P. A. (2011). Homology
modeling and functional testing of an ABCA1 mutation causing Tangier disease. Atherosclerosis. doi: 10.1016/j.
atherosclerosis.2011.06.019
Sullivan, D., Forder, P., Simes, J., Whiting, M., Kritharides, L., Merrifield, A., … for the FIELD Study Investigators, including
Manning, P. (2011). Associations between the use of metformin, sulphonylureas, or diet alone and cardiovascular
outcomes in 6005 people with type 2 diabetes in the FIELD study. Diabetes Research & Clinical Practice, 94(2), 284-290.
doi: 10.1016/j.diabres.2011.07.028
Sullivan, S. J., Hammond-Tooke, G. D., Schneiders, A. G., Gray, A. R., & McCrory, P. (2012). The diagnostic accuracy of
selected neurological tests. Journal of Clinical Neuroscience, 19(3), 423-427. doi: 10.1016/j.jocn.2011.09.011
Tannock, G. W., Tiong, I. S., Priest, P., Munro, K., Taylor, C., Richardson, A., & Schultz, M. (2011). Testing probiotic strain
Escherichia coli Nissle 1917 (Mutaflor) for its ability to reduce carriage of multidrug-resistant E. coli by elderly residents in
long-term care facilities. Journal of Medical Microbiology, 60(3), 366-370. doi: 10.1099/jmm.0.025874-0
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Seasonal variation and stability of
matrix metalloproteinase-9 activity and tissue inhibitor of matrix metalloproteinase-1 with storage at -80 oC. Clinical
Biochemistry, 44(16), 1346-1348. doi: 10.1016/j.clinbiochem.2011.08.1139
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Pro-MMP-9/TIMP-1 ratio correlates
poorly with a direct assessment of MMP-9 activity. Clinical Biochemistry, 44(17-18), 1480-1482. doi: 10.1016/j.
clinbiochem.2011.09.019
Taylor, D. R. (2012). Advances in the clinical applications of exhaled nitric oxide measurements. Journal of Breath Research,
6(4), 047102. doi: 10.1088/1752-7155/6/4/047102
Taylor, D. R. (2012). Biomarkers of inflammation in asthma: A clinical perspective. Seminars in Respiratory & Critical Care
Medicine, 33(6), 620-629. doi: 10.1055/s-0032-1326960
Taylor, D. R. (2011). Using biomarkers in the assessment of airways disease. Journal of Allergy & Clinical Immunology, 128(5),
927-934. doi: 10.1016/j.jaci.2011.03.051
Taylor, R. W., Farmer, V. L., Cameron, S. L., Meredith-Jones, K., Williams, S. M., & Mann, J. I. (2011). School playgrounds and
physical activity policies as predictors of school and home time activity. International Journal of Behavioral Nutrition &
Physical Activity, 8, 38. doi: 10.1186/1479-5868-8-38
Taylor, B. J., Heath, A.-L. M., Galland, B. C., Gray, A. R., Lawrence, J. A., Sayers, R. M., Dale, K., Coppell, K. J., Taylor, R. W.
(2011). Prevention of overweight in infancy (POI.nz) study: A randomised controlled trial of sleep, food and activity
interventions for preventing overweight from birth. BMC Public Health, 11, 942. doi: 10.1186/1471-2458-11-942
Taylor, W. J., House, M., Horne, A., McQueen, F. M., & Dalbeth, N. (2012). The work instability scale predicts absenteeism in
people with gout and suggests a higher risk for those in manual occupations. Journal of Clinical Rheumatology, 18(8), 405410. doi: 10.1097/RHU.0b013e3182779805
Taylor, D. R., Palmay, R., Cowan, J. O., & Herbison, G. P. (2011). Long term performance characteristics of an electrochemical
nitric oxide analyser. Respiratory Medicine, 105(2), 211-217. doi: 10.1016/j.rmed.2010.09.001
Taylor, R. W., Williams, S. M., Carter, P. J., Goulding, A., Gerrard, D. F., & Taylor, B. J. (2011). Changes in fat mass and fat-free
mass during the adiposity rebound: FLAME study. International Journal of Pediatric Obesity, 6(2-2), e243-e251. doi:
10.3109/17477166.2010.549488
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Taylor, R. W., Williams, S. M., Grant, A. M., Taylor, B. J., & Goulding, A. (2011). Predictive ability of waist-to-height in
relation to adiposity in children is not improved with age and sex-specific values. Obesity, 19(5), 1062-1068. doi: 10.1038/
oby.2010.217
Thamrin, C., Nydegger, R., Stern, G., Chanez, P., Wenzel, S. E., Watt, R. A., … Taylor, D. R., Frey, U. (2011). Associations
between fluctuations in lung function and asthma control in two populations with differing asthma severity. Thorax,
66(12), 1036-1042. doi: 10.1136/thx.2010.156489
Ting, Y.-T., Coates, P. T., Walker, R. J., & McLellan, A. D. (2012). Urinary tubular biomarkers as potential early predictors of
renal allograft rejection. Nephrology, 17(1), 11-16. doi: 10.1111/j.1440-1797.2011.01536.x
Tiong, I. S., Williams, M. J. A., & Perez, D. J. (2012). Nonbacterial thrombotic endocarditis with ST-elevation myocardial
infarction treated with percutaneous coronary aspiration thrombectomy. Heart, Lung & Circulation. Advance online
publication. doi: 10.1016/j.hlc.2012.10.013
Todd, A. S., MacGinley, R. J., Schollum, J. B. W., Williams, S. M., Sutherland, W. H. F., Mann, J. I., & Walker, R. J. (2012).
Dietary sodium loading in normotensive healthy volunteers does not increase arterial vascular reactivity or blood
pressure. Nephrology, 17(3), 249-256. doi: 10.1111/j.1440-1797.2011.01550.x
Tong, A., Craig, J. C., Wong, G., Morton, J., Armstrong, S., Schollum, J., & Cross, N. (2012). “It was just an unconditional
gift.” Self reflections of non-directed living kidney donors. Clinical Transplantation. Advance online publication. doi:
10.1111/j.1399-0012.2011.01578.x
Vehik, K., Beam, C. A., Mahon, J. L., Schatz, D. A., Haller, M. J., Sosenko, J. M., … for the TrialNet Natural History Study
Group, including Manning, P. (2011). Development of autoantibodies in the TrialNet Natural History study. Diabetes Care,
34(9), 1897-1901. doi: 10.2337/dc11-0560
Vehik, K., Cuthbertson, D., Ruhlig, H., Schatz, D. A., Peakman, M., Krischer, J. P., for the DPT-1 and TrialNet Study Groups,
including Manning, P. (2011). Long-term outcome of individuals treated with oral insulin: Diabetes Prevention Trial-Type
1 (DPT-1) oral insulin trial. Diabetes Care, 34(7), 1585-1590. doi: 10.2337/dc11-0523
von Zychlinski, A., Kleffmann, T., Williams, M. J. A., & McCormick, S. P. (2011). Proteomics of Lipoprotein(a) identifies
a protein complement associated with response to wounding. Journal of Proteomics, 74, 2881-2891. doi: 10.1016/j.
jprot.2011.07.008
Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J. B., & Walker, R. J. (2011). Anti-inflammatory effect of an insulin
infusion in patients on maintenance haemodialysis: A randomized controlled pilot study. Nephrology, 16(1), 68-75. doi:
10.1111/j.1440-1797.2010.01329.x
Vos, F. E., Schollum, J. B., Coulter, C. V., Doyle, T. C. A., Duffull, S. B., & Walker, R. J. (2011). Red blood cell survival in longterm dialysis patients. American Journal of Kidney Diseases, 58(4), 591-598. doi: 10.1053/j.ajkd.2011.03.031
Vos, F. E., Schollum, J. B., Coulter, C. V., Doyle, T. C. A., Duffull, S. B., & Walker, R. J. (2011). Red blood cell survival (RBC) in
patients on long-term dialysis. Nephrology, 16(Suppl. 1), 74. doi: 10.1111/j.1440-1797.2011.01493_7.x
Vos, F. E., Schollum, J. B., Coulter, C. V., Manning, P. J., Duffull, S. B., & Walker, R. J. (2012). Assessment of markers of
glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring. Nephrology,
17(2), 182-188. doi: 10.1111/j.1440-1797.2011.01517.x
Vos, F. E., Schollum, J. B., & Walker, R. J. (2011). Glycated albumin is the preferred marker for assessing glycaemic control in
advanced chronic kidney disease. NDT Plus, 4(6), 368-375. doi: 10.1093/ndtplus/sfr140
Wann, A. K. T., Zuo, N., Haycraft, C. J., Jenson, C. G., Poole, C. A., McGlashan, S. R., & Knight, M. M. (2012). Primary cilia
mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes. FASEB
Journal, 26(4), 1663-1671. doi: 10.1096/fj.11-193649
Ward, L., Treharne, G. J., & Stebbings, S. (2011). The suitability of yoga as a potential therapeutic intervention for rheumatoid
arthritis: A focus group approach. Musculoskeletal Care, 9(4), 211-221. doi: 10.1002/msc.217
Wassinger, C. A., Osborne, H., & Cury Ribeiro, D. (2011). Traumatic pneumothorax sustained via fine-wire electromyography
insertion at the shoulder. Physiotherapy, 97(4), 357-359. doi: 10.1016/j.physio.2010.12.002
Wassinger, C. A., Sole, G., & Osborne, H. (2012). The role of experimentally-induced subacromial pain on shoulder strength
and throwing accuracy. Manual Therapy, 17(5), 411-415. doi: 10.1016/j.math.2012.03.008
Watson, E., Lewis, J., & Cutfield, N. (2012). “Txt”-induced seizures indicating reading epilepsy in the mobile phone age.
Journal of Clinical Neuroscience, 19(7), 1042-1044.
Wheatley, C. M., Baldi, J. C., Cassuto, N. A., Foxx-Lupo, W. T., & Snyder, E. M. (2011). Glycemic control influences lung
membrane diffusion and oxygen saturation in exercise-trained subjects with type 1 diabetes: Alveolar-capillary membrane
conductance in type 1 diabetes. European Journal of Applied Physiology, 111(3), 567-578. doi: 10.1007/s00421-010-1663-8
White, H. D., Wong, C.-K., Gao, W., Lin, A., Benatar, J., Aylward, P. E. G., … Stewart, R. A., on behalf of the HERO-2
Investigators. (2012). New ST-depression: An under-recognized high-risk category of ‘complete’ ST-resolution after
reperfusion therapy. European Heart Journal, 1(3), 210-221. doi: 10.1177/2048872612454841
Williams, C., & Brian, G. (2012). Using health rights to improve programme design: A Papua New Guinea case study.
International Journal of Health Planning & Management, 27(3), 246-256. doi: 10.1002/hpm.2103
Williams, S., Brian, G., & du Toit, R. (2012). Measuring vision-specific quality of life among adults in Fiji. Ophthalmic
Epidemiology, 19(6), 388-395. doi: 10.3109/09286586.2012.716896
Williams, S. M., Taylor, R. W., & Taylor, B. J. (2012). Secular changes in BMI and the associations between risk factors and BMI
in children born 29 years apart. Pediatric Obesity. Advance online publication. doi: 10.1111/j.2047-6310.2012.00081.x
Wimer, G. S., & Baldi, J. C. (2012). Limb-specific training affects exercise hyperemia but not sympathetic vasoconstriction.
European Journal of Applied Physiology, 112(11), 3819-3828.
169
RESEARCH REPORT 2011/2012
Winburn, I. C., Gunatunga, K., McKernan, R. D., Walker, R. J., Sammut, I. A., & Harrison, J. C. (2012). Cell damage following
carbon monoxide releasing molecule exposure: Implications for therapeutic applications. Basic & Clinical Pharmacology &
Toxicology, 111(1), 31-41. doi: 10.1111/j.1742-7843.2012.00856.x
Wong, C.-K. (2012). Acceptable transfer delay to primary PCI vs on-site fibrinolysis for STEMI: Can ECG parameters help
clinical judgment? International Journal of Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.11.049
Wong, C.-K. (2011). The evolution of reperfusion management in patients with suspected myocardial infarction and bundle
branch block: How ECG language will intertwine with angiographic findings [Letter]. International Journal of Cardiology,
153(3), 326-327. doi: 10.1016/j.ijcard.2011.09.043
Wong, C.-K., Gao, W., Stewart, R. A. H., French, J. K., Aylward, P. E. G., White, H. D., for the HERO-2 Investigators. (2012).
The prognostic meaning of the full spectrum of aVR ST-segment changes in acute myocardial infarction. European Heart
Journal, 33(3), 384-392. doi: 10.1093/eurheartj/ehr301
Wong, C.-K., & Herbison, P. (2011). Initial Q waves and outcome after reperfusion therapy in patients with ST elevation
acute myocardial infarction: A systematic review. International Journal of Cardiology, 148(3), 305-308. doi: 10.1016/j.
ijcard.2009.11.013
Wong, C.-K., Leon de la Barra, S., & Herbison, P. (2012). Role of routine early angiography post-fibrinolysis for ST elevation
myocardial infarction: A meta-regression analysis using angiography rate in the non-routine arm. International Journal of
Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.04.151
Wong, C.-K., & White, H. D. (2012). Patients with circumflex occlusions miss out on reperfusion: How to recognize and
manage them. Current Opinion in Cardiology, 27(4), 327-330. doi: 10.1097/HCO.0b013e32835482b7
Wong, C.-K., & White, H. D. (2011). Antithrombotic therapy in ST-segment elevation myocardial infarction. Expert Opinion
on Pharmacotherapy, 12(2), 213-223. doi: 10.1517/14656566.2010.518613
Wong, C.-K., & White, H. D. (2011). Effects of dietary factors on lipoprotein-associated phospholipase A2 (Lp-PLA2). Current
Atherosclerosis Reports, 13(6), 461-466. doi: 10.1007/s11883-011-0201-4
Woolley, A. G., Algie, M., Samuel, W., Harfoot, R., Wiles, A., Hung, N. A., … Royds, J. A., Perez, D., Yoon, H.-S., … Braithwaite,
A. W. (2011). Prognostic association of YB-1 expression in breast cancers: A matter of antibody. PLoS ONE, 6(6), e20603.
doi: 10.1371/journal.pone.0020603
Wu, P.-C., Tiong, I. S., Chuang, Y.-C., & Kuo, H.-K. (2011). Twisting maneuver for sutureless vitrectomy trocar insertion to
reduce intraoperative intraocular pressure rise. Retina, 31(5), 887-892. doi: 10.1097/IAE.0b013e3181f57d8a
Yeung, S. S., Yeung, E. W., & Gillespie, L. D. (2011). Interventions for preventing lower limb soft-tissue running injuries
(Review). Cochrane Database of Systematic Reviews, 7, CD001256. doi: 10.1002/14651858.CD001256.pub2
Journal - Research Other
Non ST-Elevation Acute Coronary Syndrome Guidelines Group, and the New Zealand Branch of the Cardiac Society of
Australia and New Zealand, including Wong, C.-K., Smyth, D., Wilkins, G., Crozier, I., Elliott, J., Simmonds, M., Williams,
M., Matsis, P., Harding, S., Mann, S. (2012). New Zealand 2012 guidelines for the management of non ST-elevation acute
coronary syndromes [Special article]. New Zealand Medical Journal, 125(1357). Retrieved from http://journal.nzma.org.
nz/journal/125-1357/5245/content.pdf.
Chu, J. W., Chen, V. H. T., & Bunton, R. (2012). Thrombosis of a mechanical heart valve despite dabigatran [Letter]. Annals of
Internal Medicine, 157(4), 304.
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2011). Plasma active
matrix metalloproteinase 9 associated to diastolic dysfunction in patients with coronary artery disease [Letter].
International Journal of Cardiology, 147(2), 336-338. doi: 10.1016/j.ijcard.2010.12.093
Coffey, S., & Williams, M. (2011). Quetiapine-associated cardiomyopathy [Clinical correspondence]. New Zealand Medical
Journal, 124(1337). Retrieved from http://journal.nzma.org.nz/journal/124-1337/4744/content.pdf.
Coppell, K. (2012). In people with newly diagnosed type 2 diabetes an intensive dietary intervention, with or without an
activity programme, improves glycaemic control over 12 months compared with usual care [Commentary]. EvidenceBased Medicine, 17, 85-86. doi: 10.1136/ebm.2011.100193
Cutfield, N. J., Seemungal, B. M., Millington, H., & Bronstein, A. M. (2011). Diagnosis of acute vertigo in the emergency
department [Letter]. Emergency Medicine Journal, 28(6), 538-539. doi: 10.1136/emj.2010.105874
Highton, J., Stebbings, S., & Jenks, K. (2012). The intestinal microbiome in ankylosing spondylitis: Comment on the article by
Rosenbaum and Davey. [Letter to the editor]. Arthritis & Rheumatism, 64(2), 597-598. doi: 10.1002/art.33406
Hsu, A., Dalbeth, N., Gow, P., Harrison, A., Highton, J., Jones, P. B., Stamp, L. K., Merriman, T. R. (2012). No evidence for
association of Chr 9p21 variant rs1333049 with gout in New Zealand case-control sample sets [Letter to the editor].
Rheumatology, 51, 1129-1130. doi: 10.1093/rheumatology/kes029
Jones, S., Whitehead, O., & Brian, G. (2012). Trachoma in Far North Queensland: An example of poor population health
practice [Letter to the editor]. Clinical & Experimental Ophthalmology. Advance online publication. doi: 10.1111/ceo.12038
Lam, K., Guo, H., Wilson, G. A., Kohl, S., & Wong, F. (2011). Identification of variants in CNGA3 as cause for
achromatopsia by exome sequencing of a single patient. Archives of Ophthalmology, 129(9), 1212-1217. doi: 10.1001/
archophthalmol.2011.254
Melnychuk, I., & Busby, W. (2011). Rash and fever in a college student [Case Study]. American Family Physician, 84(6), 697-698.
Nadarasa, K., Chen, V. H. T., Galvin, S., & van der Linden, A. (2011). A large tricuspid valve mass associated with rectal
carcinoma [Clinical correspondence]. New Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.
nz/journal/124-1340/4812/content.pdf.
170
RESEARCH REPORT 2011/2012
Pan, A., Doyle, T., Schlup, M., Lubcke, R., & Schultz, M. (2011). Unusual manifestation of Erdheim-Chester disease. BMC
Gastroenterology, 11, 77. doi: 10.1186/1471-230x-11-77
Pettigrew, D. J., & Osborne, H. R. (2011). Not all wrist lumps are ganglia. New Zealand Journal of Sports Medicine, 38(2), 61-62.
Phipps-Green, A., McKinney, C., Rossol, M., Merriman, M. E., Topless, R., Hollis-Moffatt, J. E., Wan Taib, W. R., … Harrison,
A. A., Highton, J., … Stamp, L. K., … Merriman, T. R. (2011). Analysis of association of DNASE2 promoter variation with
rheumatoid arthritis in European Caucasians [Letter]. Annals of the Rheumatic Diseases, 70(8), 1512-1514. doi: 10.1136/
ard.2010.138727
Qoqonokana, M. Q., Brian, T., Ale Magar, J. B., & Brian, G. (2012). Glaucoma in Timor-Leste: A population-based study
[Letter to the editor]. Clinical & Experimental Ophthalmology. Advance online publication. doi: 10.1111/j.14429071.2012.02853.x
Ramke, J., Blignault, I., Hobday, K., Lee, L., & Brian, G. (2012). Primary eye care in Timor-Leste [Letter to the editor]. British
Journal of Ophthalmology, 96(1), 143-145. doi: 10.1136/bjophthalmol-2011-300730
Ramke, J., Lee, L., & Brian, G. (2012). Prevalence of diabetes among adults aged ≥40 years in Timor-Leste [Letter]. Journal of
Diabetes, 4(4), 392-394. doi: 10.1111/j.1753-0407.2012.00217.x
Ramke, J., Qoqonokana, M. Q., & Brian, G. (2011). Diabetes and its ocular complications in Timor-Leste [Letter to the editor].
Clinical & Experimental Ophthalmology, 39(8), 843-844. doi: 10.1111/j.1442-9071.2011.02540.x
Schultz, M., & Butt, A. G. (2012). Is the north to south gradient in inflammatory bowel disease a global phenomenon? Expert
Review of Gastroenterology & Hepatology, 6(4), 445-447. doi: 10.1586/egh.12.31
Signal, L., Firestone, R., Mann, J., Ni Mhurchu, C., Lawrenson, R., Murphy, R., … Skeaff, C. M., Taylor, R., … Walton, M.
(2011). New Zealand’s shocking diabetes rates can be reduced — 9 urgently needed actions [Letter]. New Zealand Medical
Journal, 124(1340). Retrieved from http://journal.nzma.org.nz/journal/124-1340/4822/content.pdf.
Stewart, R. E., & Osborne, H. R. (2011). Stenosing flexor tenovaginitis ‘Trigger finger.’. New Zealand Journal of Sports Medicine,
38(1), 30-31.
Taylor, R. (2011). [Review of the book Childhood obesity prevention: International research, controversies, and interventions].
Nutrition & Dietetics, 68(3), 240-241. doi: 10.1111/j.1747-0080.2011.01539.x
Thomas, M., & Taylor, D. R. (2011). Assessing inflammatory phenotypes and improving the cost-effectiveness of asthma and
COPD care in the community [Editorial]. Primary Care Respiratory Journal, 20(4), 349-350. doi: 10.4104/pcrj.2011.00087
Wong, C.-K. (2012). When should a non-STEMI be treated with primary PCI as for STEMIs? [Letter to the editor].
International Journal of Cardiology, 158(3), 477-478. doi: 10.1016/j.ijcard.2012.05.063
Wong, C.-K. (2012). How much does AVR ST change help stratify patients with coronary disease? [Letter]. International
Journal of Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.09.125
Wong, C.-K. (2011). Usefulness of leads V7, V8, and V9 ST elevation to diagnose isolated posterior myocardial infarction
[Letter to the editor]. International Journal of Cardiology, 146(3), 467-469. doi: 10.1016/j.ijcard.2010.10.137
Wong, C.-K. (2011). Isolated right ventricular infarction as a cause for anterior (V1-V3) ST elevation — Review of
publications since 2006 and re-appraisal of direct vs reciprocal ST changes [Letter to the editor]. International Journal of
Cardiology, 151(2), 239-241. doi: 10.1016/j.ijcard.2011.06.059
Wong, C.-K. (2011). Detecting ST deviations: Does body surface mapping help or have we missed information from lead aVR?
[Letter to the editor]. International Journal of Cardiology, 152(3), 403-407. doi: 10.1016/j.ijcard.2011.08.041
Journal - Professional & Other Non-Research Articles
Barbezat, G., & Cundy, T. (2011). Wilhelm Frederick Lubbe [Obituary]. New Zealand Medical Journal, 124(1329). Retrieved
from http://journal.nzma.org.nz/journal/124-1329/4542/content.pdf.
Dweik, R. A., Boggs, P. B., Taylor, D. R., on behalf of the authors. (2012). Reply from the authors to Transparent reporting of
all GRADE criteria in Clinical Practice Guidelines [Letter to the editor]. American Journal of Respiratory & Critical Care
Medicine, 185(10), 1129-1130.
Dunedin School of Medicine
Pathology
Authored Book - Research
Chatterjee, A., & Pan, A. (2012). Genome and proteome composition of Bdellovibrio bacteriovorus: Indications of recent horizontal
gene transfer in Bdellovibrio bacteriovorus. Saarbrücken, Germany: Lambert Academic, 112p.
Chapter in Book - Research
Yoon, H.-S., & Eccles, M. R. (2011). Mild forms of Alport syndrome: Hereditary nephropathy in the absence of extra-renal
features. In S. S. Prabhakar (Ed.), An update of glomerulopathies: Clinical and treatment aspects (pp. 417-436). Rijeka,
Croatia: InTech. Retrieved from http://www.intechopen.com.
Journal - Research Article
Bordé, E. C., Ouzegdouh, Y., Ledgerwood, E. C., & Morison, I. M. (2011). Congenital thrombocytopenia and cytochrome c
mutation: A matter of birth and death. Seminars in Thrombosis & Hemostasis, 37(6), 664-672. doi: 10.1055/s-0031-1291376
Bower, M., Eccles, M., Heidet, L., & Schimmenti, L. A. (2011). Clinical utility gene card for: Renal coloboma (Papillorenal)
syndrome. European Journal of Human Genetics, 19(9). doi: 10.1038/ejhg.2011.16
171
RESEARCH REPORT 2011/2012
Bower, M., Salomon, R., Allanson, J., Antignac, C., Benedicenti, F., Benetti, E., … Dixon, J., … Eccles, M., … Heidet, L. (2012).
Update of PAX2 mutations in renal coloboma syndrome and establishment of locus-specific database. Human Mutation,
33(3), 457-466. doi: 10.1002/humu.22020
Burger, M. C., Brucker, D. P., Baumgarten, P., Ronellenfitsch, M. W., Wanka, C., Hasselblatt, M., Eccles, M. R., … Steinbach,
J. P. (2012). PAX2 is an antiapoptotic molecule with deregulated expression in medulloblastoma. International Journal of
Oncology, 41(1), 235-241. doi: 10.3892/ijo.2012.1446
Campbell, H. G., Slatter, T. L., Jeffs, A., Mehta, R., Rubio, C., Baird, M., & Braithwaite, A. W. (2012). Does Δ133p53 isoform
trigger inflammation and autoimmunity?. Cell Cycle, 11(3), 446-450. doi: 10.4161/cc.11.3.19054
Chatterjee, A., & Basu, A. (2011). Rubisco: Limitations and re-engineering for a better enzyme. International Research Journal
of Plant Science, 2(2), 022-024.
Chatterjee, A., Rodger, E. J., Stockwell, P. A., Weeks, R. J., & Morison, I. M. (2012). Technical considerations for reduced
representation bisulfite sequencing with multiplexed libraries. Journal of Biomedicine & Biotechnology, 2012, 741542. doi:
10.1155/2012/741542
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2012). Comparison of alignment software for genome-wide
bisulphite sequence data. Nucleic Acids Research, 40(10), e79. doi: 10.1093/nar/gks150
Coffey, S., Nadarasa, K., Pan, A., van der Linden, A., Chu, J., & Schultz, M. (2012). The increasing incidence of Streptococcus
bovis endocarditis and bacteraemia: A case series from 1997 to 2010. International Journal of Cardiology, (0). Advance
online publication. doi: 10.1016/j.ijcard.2012.06.031
Deardorff, M. A., Wilde, J. J., Albrecht, M., Dickinson, E., Tennstedt, S., Braunholz, D., Mönnich, M., … Horsfield, J. A., Kaiser,
F. J. (2012). RAD21 mutations cause a human cohesinopathy. American Journal of Human Genetics, 90(6), 1014-1027. doi:
10.1016/j.ajhg.2012.04.019
Debono, R., Topless, R., Markie, D., Black, M. A., & Merriman, T. R. (2012). Analysis of the DISC1 translocation partner
(11q14.3) in genetic risk of schizophrenia. Genes, Brain & Behavior. Advance online publication. doi: 10.1111/j.1601183X.2012.00832.x
Glue, P., Gale, C., Menkes, D. B., & Hung, N. (2012). Evaluation of bioequivalence between clozapine suspension and tablet
formulations : A multiple-dose, fed and fasted Study. Clinical Drug Investigation, 32(11), 723-727. doi: 10.1007/s40261012-0004-6
Gulati, A., Faed, J. M., Isbister, G. K., & Duffull, S. B. (2012). Development and evaluation of a prototype of a novel clotting
time test to monitor enoxaparin. Pharmaceutical Research, 29(1), 225-235. doi: 10.1007/s11095-011-0537-z
He, S., Li, C. G., Slobbe, L., Glover, A., Marshall, E., Baguley, B. C., & Eccles, M. R. (2011). PAX3 knockdown in
metastatic melanoma cell lines does not reduce MITF expression. Melanoma Research, 21(1), 24-34. doi: 10.1097/
CMR.0b013e328341c7e0
Horsfield, J. A., Print, C. G., & Mönnich, M. (2012). Diverse developmental disorders from The One Ring: Distinct molecular
pathways underlie the cohesinopathies. Frontiers in Genetics, 3, 171. doi: 10.3389/fgene.2012.00171
Huschtscha, L. I., Napier, C. E., Noble, J. R., Bower, K., Au, A. Y. M., Campbell, H. G., Braithwaite, A. W., Reddell, R. R. (2012).
Enhanced isolation of fibroblasts from human skin explants. Biotechniques, 53(4), 239-244. doi: 10.2144/0000113939
Ineson, J., Stayner, C., Hazlett, J., Slobbe, L., Robson, E., Legge, M., & Eccles, M. R. (2012). Somatic reactivation of expression
of the silent maternal Mest allele and acquisition of normal reproductive behaviour in a colony of Peg1/Mest mutant mice.
Journal of Reproduction & Development, 58(4), 490-500.
Joshi, S., Braithwaite, A. W., Robinson, P. J., & Chircop, M. (2011). Dynamin inhibitors induce caspase-mediated apoptosis
following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression. Molecular Cancer, 10, 78.
doi: 10.1186/1476-4598-10-78
Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations
in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer
Research, 30, 78. doi: 10.1186/1756-9966-30-78
Lasham, A., Samuel, W., Cao, H., Patel, R., Mehta, R., Stern, J. L., … Woolley, A. G., … Black, M. A., Shelling, A. N., Print, C.
G., Braithwaite, A. . (2012). YB-1, the E2F Pathway, and regulation of tumor cell growth. Journal of the National Cancer
Institute, 104(2), 133-146. doi: 10.1093/jnci/djr512
Laskar, A., Chatterjee, A., Chatterjee, S., & Rodger, E. J. (2012). Three-dimensional molecular modeling of a diverse range of
SC clan serine proteases. Molecular Biology International, 2012, 580965. doi: 10.1155/2012/580965
Laskar, A., Rodger, E. J., Chatterjee, A., & Mandal, C. (2012). Modeling and structural analysis of PA clan serine proteases.
BMC Research Notes, 5, 256. doi: 10.1186/1756-0500-5-256
Laskar, A., Rodger, E. J., Chatterjee, A., & Mandal, C. (2011). Modeling and structural analysis of evolutionarily diverse S8
family serine proteases. Bioinformation, 7(5), 239-245.
Li, C. G., & Eccles, M. R. (2012). PAX genes in cancer: Friends or foes? Frontiers in Genetics, 3, 6. doi: 10.3389/fgene.2012.00006
Li, C. G., Nyman, J. E., Braithwaite, A. W., & Eccles, M. R. (2011). PAX8 promotes tumor cell growth by transcriptionally
regulating E2F1 and stabilizing RB protein. Oncogene, 30, 4824-4834. doi: 10.1038/onc.2011.190
Ludgate, J. L., Le Mée, G., Fukuzawa, R., Rodger, E. J., Weeks, R. J., Reeve, A. E., & Morison, I. M. (2012). Global demethylation
in loss of imprinting subtype of wilms tumor. Genes Chromosomes & Cancer. Advance online publication. doi: 10.1002/
gcc.22017
Macaulay, E. C., Weeks, R. J., Andrews, S., & Morison, I. M. (2011). Hypomethylation of functional retrotransposon-derived
genes in the human placenta. Mammalian Genome, 22, 722-735. doi: 10.1007/s00335-011-9355-1
172
RESEARCH REPORT 2011/2012
Marsman, J., & Horsfield, J. A. (2012). Long distance relationships: Enhancer-promoter communication and dynamic gene
transcription. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms. Advance online publication. doi: 10.1016/j.
bbagrm.2012.10.008
McEwan, M. V., Eccles, M. R., & Horsfield, J. A. (2012). Cohesin is required for activation of MYC by estradiol. PLOS ONE,
7(11), e49160. doi: 10.1371/journal.pone.0049160
McKee, S. J., Young, V. L., Clow, F. M., Hayman, C. M., Baird, M. A., Hermans, I. F., Young, S. L., Ward, V. K. (2012). Virus-like
particles and α-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses. Journal of
Controlled Release, 159(3), 338-345. doi: 10.1016/j.jconrel.2012.02.015
Miller, J. C., Thomson, C. D., Williams, S. M., van Havre, N., Wilkins, G. T., Morison, I. M., Ludgate, J. L., Skeaff, C. M. (2012).
Influence of the glutathione peroxidase 1 Pro200Leu polymorphism on the response of glutathione peroxidase activity
to selenium supplementation: A randomized controlled trial. American Journal of Clinical Nutrition, 96, 923-931. doi:
10.3945/ajcn.112.043125
Mönnich, M., Kuriger, Z., Print, C. G., & Horsfield, J. A. (2011). A zebrafish model of Roberts syndrome reveals that Esco2
depletion interferes with development by disrupting the cell cycle. PLoS ONE, 6(5), e20051. doi: 10.1371/journal.
pone.0020051
O’Sullivan, P., Sharples, K., Dalphin, M., Davidson, P., Gilling, P., Cambridge, L., Yoon, H.-S., … Guilford, P. J. (2012). A
multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria. Journal of
Urology, 188(3), 741-747. doi: 10.1016/j.juro.2012.05.003
Oliver, V. F., Miles, H. L., Cutfield, W. S., Hofman, P. L., Ludgate, J. L., & Morison, I. M. (2012). Defects in imprinting and
genome-wide DNA methylation are not common in the in vitro fertilization population. Fertility & Sterility, 97(1), 147153.e7. doi: 10.1016/j.fertnstert.2011.10.027
Otto, E. A., Ramaswami, G., Janssen, S., Chaki, M., Allen, S. J., Zhou, W., … and the GPN Study Group, including Eccles,
M. (2011). Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next
generation sequencing strategy. Journal of Medical Genetics, 48, 105-116. doi: 10.1136/jmg.2010.082552
Rhodes, J. M., McEwan, M., & Horsfield, J. A. (2011). Gene regulation by cohesin in cancer: Is the ring an unexpected party to
proliferation? Molecular Cancer Research, 9(12), 1587-1607. doi: 10.1158/1541-7786.mcr-11-0382
Richter, K. K., Dempster, A., Tos, A. P. D., Premkumar, R., & Jackson, C. (2011). Challenging differential diagnosis of a wildtype gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational
analysis. New Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4583/
content.pdf.
Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction
of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi:
10.1016/j.atherosclerosis.2011.04.043
Rodger, E. J., & Morison, I. M. (2012). Myelodysplastic syndrome in New Zealand and Australia. Internal Medicine Journal,
42(11), 1235-1242. doi: 10.1111/j.1445-5994.2011.02619.x
Rodger, E. J., Suetani, R. J., Jones, G. T., Kleffmann, T., Carne, A., Legge, M., & McCormick, S. P. A. (2012). Proteomic analysis
of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis.
PLoS ONE, 7(1), e30383. doi: 10.1371/journal.pone.0030383
Royds, J. A., Al Nadaf, S., Wiles, A. K., Chen, Y.-J., Ahn, A., Shaw, A., Bowie, S., … Braithwaite, A. W., … Hung, N. A., Slatter, T.
L. (2011). The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism
tumors and is associated with poorer survival. PLoS ONE, 6(10), e26737. doi: 10.1371/journal.pone.0026737
Rudland, J. R., Schwartz, P., & Ali, A. (2011). Moving a formative test from a paper-based to a computer-based format: A
student viewpoint. Medical Teacher, 33(9), 738-743. doi: 10.3109/0142159X.2011.577119
Sears, C., Markie, D., Olds, R., & Fitches, A. (2011). Evidence of associations between bipolar disorder and the brain-derived
neurotrophic factor (BDNF) gene. Bipolar Disorders, 13(7-8), 630-637. doi: 10.1111/j.1399-5618.2011.00955.x
Sidhapuriwala, J. N., Hegde, A., Ang, A. D., Zhu, Y. Z., & Bhatia, M. (2012). Effects of S-Propargyl-Cysteine (SPRC) in
caerulein-induced acute pancreatitis in mice. PLoS ONE, 7(3), e32574. doi: 10.1371/journal.pone.0032574
Sinon, S. H., Rich, A. M., Hussaini, H. M., Yoon, H.-S., Firth, N. A., & Seymour, G. J. (2011). Metastases to the oral region from
pleural mesothelioma: Clinicopathologic review. Head & Neck. Advance online publication. doi: 10.1002/hed.21942
Slatter, T. L., Hung, N., Campbell, H., Rubio, C., Mehta, R., Renshaw, P., Williams, G., Wilson, M., … Jeffs, A., Royds, J. A.,
Baird, M. A., Braithwaite, A. W. (2011). Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like
isoform. Blood, 117(19), 5166-5177. doi: 10.1182/blood-2010-11-321851
Slatter, T. L., Tan, X., Yuen, Y. C., Gunningham, S., Ma, S. S., Daly, E., Packer, S., Devenish, C., Royds, J. A., Hung, N. A. (2012).
The alternative lengthening of telomeres pathway operates in non-neoplastic human cells. Journal of Pathology, 226(3),
509-518. doi: 10.1002/path.2981
Stayner, C., Shields, J., Slobbe, L., Shillingford, J. M., Weimbs, T., & Eccles, M. R. (2012). Rapamycin-mediated suppression of
renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: An investigation of the feasibility of renal cyst prevention in
the fetus. Nephrology. Advance online publication. doi: 10.1111/j.1440-1797.2012.01639.x
Stringer, M. D., Restieaux, M., Fisher, A. L., & Crosado, B. (2012). The vertebral venous plexuses: The internal veins are
muscular and external veins have valves. Clinical Anatomy, 25(5), 609-618. doi: 10.1002/ca.21281
Tang, R., Li, K., Wilson, M., Both, G. W., Taylor, J. A., & Young, S. L. (2012). Potent antietumor immunity in mice
induced by vaccination with an ovine Atadenovirus vector. Journal of Immunotherapy, 35(1), 32-41. doi: 10.1097/
CJI.0b013e318238a115
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Tweed, M., Thompson-Fawcett, M., Schwartz, P., & Wilkinson, T. J. (2012). Determining measures of insight and
foresight from responses to multiple choice questions. Medical Teacher. Advance online publication. doi:
10.3109/0142159x.2012.733834
Tweed, M. J., Thomson-Fawcett, M., Schwartz, P., & Wilkinson, T. J. (2012). A confidence and safety approach to multiplechoice question scoring. Focus on Health Professional Education, 13(3), 84-92.
Wilson, J., Markie, D., & Fitches, A. (2012). Cholecystokinin system genes: Associations with panic and other psychiatric
disorders. Journal of Affective Disorders, 136(3), 902-908. doi: 10.1016/j.jad.2011.09.011
Win, S. J., McMillan, D. G. G., Errington-Mais, F., Ward, V. K., Young, S. L., Baird, M. A., & Melcher, A. A. (2011). Enhancing
the immunogenicity of tumour lysate-loaded dendritic cell vaccines by conjugation to virus-like particles. British Journal
of Cancer, 106, 92-98. doi: 10.1038/bjc.2011.538
Woolley, A. G., Algie, M., Samuel, W., Harfoot, R., Wiles, A., Hung, N. A., … Royds, J. A., Perez, D., Yoon, H.-S., … Braithwaite,
A. W. (2011). Prognostic association of YB-1 expression in breast cancers: A matter of antibody. PLoS ONE, 6(6), e20603.
doi: 10.1371/journal.pone.0020603
Journal - Research Other
Abad, C., Antczak, D. F., Carvalho, J., Chamley, L. W., Chen, Q., Daher, S., … Daly, E., … Lash, G. E. (2011). IFPA Meeting
2010 Workshop Report I: Immunology; ion transport; Epigenetics; Vascular reactivity; Epitheliochorial placentation;
Proteomics. Placenta, 32(Suppl. 2), S81-S89. doi: 10.1016/j.placenta.2010.12.019
Chatterjee, A. (2012). Epigenetic regulation: From mechanism to intervention. Epigenomics, 4(5), 487-490. doi: 10.2217/epi.12.47
Chatterjee, A., & Morison, I. M. (2011). Monozygotic twins: Genes are not the destiny? [Views and challenges]. Bioinformation,
7(7), 369-370.
Duffull, S. B., Wright, D. F. B., Al-Sallami, H. S., Zufferey, P. J., & Faed, J. M. (2012). Dabigatran: Rational dose individualisation
and monitoring guidance is needed. New Zealand Medical Journal, 125(1357). Retrieved from http://journal.nzma.org.nz/
journal/125-1357/5235/content.pdf.
Duncan, G., Stevens, G., Boberg, C., Harman, R., Eccles, M., Marshall, B., … Rademaker, M. (2011). Melanoma Summit
highlights best practice and priorities for action [Letter]. New Zealand Medical Journal, 124(1334). Retrieved from http://
journal.nzma.org.nz/journal/124-1334/4670/content.pdf.
Eccles, M. (2011). Is cancer the next of kin to the developing foetus? Australasian Science, 32(10), 26-27.
Nadarasa, K., Chen, V. H. T., Galvin, S., & van der Linden, A. (2011). A large tricuspid valve mass associated with rectal
carcinoma [Clinical correspondence]. New Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.
nz/journal/124-1340/4812/content.pdf.
Richter, K. K., Premkumar, R., Yoon, H.-S., & Mercer, P. (2011). Laparoscopic adrenalectomy for a rare 14-cm adrenal
schwannoma [Case report]. Surgical Laparoscopy Endoscopy & Percutaneous Techniques, 21(6), e339-e343. doi: 10.1097/
SLE.0b013e31823ac4d4
Wilson, J., Markie, D., & Fitches, A. (2011). Analysis of associations for candidate genes with anxiety disorders [Letter to the
editor]. Psychiatry Research, 189(30), 624-625. doi: 10.1016/j.psychres.2011.06.021
Awarded Doctoral Degree
Macaulay, E. C. (2011). An epigenetic analysis of the human placenta (PhD). University of Otago, Dunedin, New Zealand. 269p.
Dunedin School of Medicine
Dunedin Multidisciplinary Health & Development Research Unit, Preventive and Social Medicine
Authored Book - Research
Nairn, K., Higgins, J., & Sligo, J. (2012). Children of Rogernomics: A neoliberal generation leaves school. Dunedin, New Zealand:
Otago University Press, 196p.
Chapter in Book - Research
Craig, D., & Kimchoeun, P. (2011). Party financing of local investment projects: Elite and mass patronage. In C. Hughes & K.
Un (Eds.), Cambodia’s economic transformation (pp. 219-244). Copenhagen, Denmark: NIAS.
Poulton, R. (2011). Self-control. In P. Gluckman & H. Hayne (Eds.), Improving the transition: Reducing social and psychological
morbidity during adolescence: A report from the Prime Minister’s Chief Science Advisor (pp. 49-57). Auckland, New Zealand:
Office of the Prime Minister’s Science Advisory Committee.
Journal - Research Article
Belsky, J., Hancox, R. J., Sligo, J., & Poulton, R. (2012). Does being an older parent attenuate the intergenerational transmission
of parenting? Developmental Psychology, 48(6), 1570-1574. doi: 10.1037/a0027599
Belsky, D. W., Moffitt, T. E., Houts, R., Bennett, G. G., Biddle, A. K., Blumenthal, J. A., … Poulton, R., Caspi, A. (2012).
Polygenic risk, rapid childhood growth, and the development of obesity: Evidence from a 4-decade longitudinal study.
Archives of Pediatrics & Adolescent Medicine, 166(6), 515-521.
Crocombe, L. A., Broadbent, J. M., Thomson, W. M., Brennan, D. S., & Poulton, R. (2012). Impact of dental visiting trajectory
patterns on clinical oral health and oral health-related quality of life. Journal of Public Health Dentistry, 72(1), 36-44. doi:
10.1111/j.1752-7325.2011.00281.x
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Gregory, A. M., Moffitt, T. E., Ambler, A., Arseneault, L., Houts, R. M., & Caspi, A. (2012). Maternal insomnia and children’s
family socialization environments. Sleep, 35(4), 579-582. doi: 10.5665/sleep.1750
Grisham, J. R., Fullana, M. A., Mataix-Cols, D., Moffitt, T. E., Caspi, A., & Poulton, R. (2011). Risk factors prospectively
associated with adult obsessive—compulsive symptom dimensions and obsessive-compulsive disorder. Psychological
Medicine, 41(12), 2495-2506. doi: 10.1017/S0033291711000894
Hulme, S. R., Jones, O. D., Ireland, D. R., & Abraham, W. C. (2012). Calcium-dependent but action potentialindependent BCM-like metaplasticity in the hippocampus. Journal of Neuroscience, 32(20), 6785-6794. doi: 10.1523/
jneurosci.0634-12.2012
Meier, M. H., Caspi, A., Ambler, A., Harrington, H., Houts, R., Keefe, R. S. E., McDonald, K., Ward, A., Poulton, R., Moffitt, T.
E. (2012). Persistent cannabis users show neuropsychological decline from childhood to midlife. PNAS. Advance online
publication. doi: 10.1073/pnas.1206820109
Peres, M. A., Thomson, W. M., Peres, K. G., Gigante, D. P., Horta, B. L., Broadbent, J. M., & Poulton, R. (2011). Challenges in
comparing the methods and findings of cohort studies of oral health: The Dunedin (New Zealand) and Pelotas (Brazil)
studies. Australian & New Zealand Journal of Public Health, 35(6), 549-556. doi: 10.1111/j.1753-6405.2011.00736.x
Reeves, L. M., Priest, P. C., & Poore, M. R. (2012). School toilets: Facilitating hand hygiene? A review of primary school hygiene
facilities in a developed country. Journal of Public Health. Advance online publication. doi: 10.1093/pubmed/fds028
Shearer, D. M., Thomson, W. M., Broadbent, J. M., & Poulton, R. (2011). Does maternal oral health predict child oral healthrelated quality of life in adulthood? Health & Quality of Life Outcomes, 9, 50. doi: 10.1186/1477-7525-9-50
Shearer, D. M., Thomson, W. M., Caspi, A., Moffitt, T. E., Broadbent, J. M., & Poulton, R. (2012). Family history and oral
health: Findings from the Dunedin Study. Community Dentistry & Oral Epidemiology, 40(2), 105-115. doi: 10.1111/j.16000528.2011.00641.x
Sligo, J. L., Buxton, J., McComb, S., Rothstein, D., Salter, G. H., & Hancox, R. J. (2011). How do we capture 15 years of complex
and meaningful data about young people’s lives? Kötuitui, 6(1-2), 37-49. doi: 10.1080/1177083X.2011.614624
Slutske, W. S., Moffitt, T. E., Poulton, R., & Caspi, A. (2012). Undercontrolled temperament at age 3 predicts disordered
gambling at age 32: A longitudinal study of a complete birth cohort. Psychological Science, 23(5), 510-516. doi:
10.1177/0956797611429708
Sridhar, D., & Craig, D. (2011). Analysing global health assistance: The reach for ethnographic, institutional and political
economic scope. Social Science & Medicine, 72(12), 1915-1920. doi: 10.1016/j.socscimed.2011.05.002
Thomson, W. M., Caspi, A., Poulton, R., Moffitt, T. E., & Broadbent, J. M. (2011). Personality and oral health. European Journal
of Oral Sciences, 119(5), 366-372. doi: 10.1111/j.1600-0722.2011.00840.x
Thomson, W. M., Mejia, G. C., Broadbent, J. M., & Poulton, R. (2012). Construct validity of Locker’s global oral health item.
Journal of Dental Research, 91(11), 1038-1042. doi: 10.1177/0022034512460676
Journal - Research Other
Ward, A., & Weiss, H. (2011). Mobility management for prevented, reduced, or delayed driving in teenagers (Protocol).
Cochrane Database of Systematic Reviews, 11, CD009438. doi: 10.1002/14651858.CD009438
Wood, W., & Craig, D. (2011). [Review of the book Punishing the poor: The neoliberal government of social insecurity]. British
Journal of Sociology, 62(3), 555-557. doi: 10.1111/j.1468-4446.2011.01379_4.x
Commissioned Report for External Body
Early Childhood Education Taskforce, including Poulton, R., & Smith, A. (2011). An agenda for amazing children: Final Report
of the ECE Taskforce. Commissioned by Ministry of Education. Wellington, New Zealand: Ministry of Education. 212p.
Tustin, K., Chee, K.-S., Taylor, N., Gollop, M., Taumoepeau, M., Hunter, J., Harold, G., Poulton, R. (2012). Extended Baseline
Report: Graduate Longitudinal Study New Zealand. Commissioned by Universities New Zealand. 293p. Retrieved from
http://www.glsnz.org.nz/.
Working Paper; Discussion Paper; Technical Report
Advisory Group on Conduct Problems, including Fergusson, D., & Poulton, R. (2011). Conduct problems: Effective services for
8-12 year-olds. Wellington, New Zealand: Ministry of Social Development. 132p.
Dunedin School of Medicine
Hugh Adam Cancer Epidemiology Unit, Preventive and Social Medicine
Journal - Research Other
Cox, B., & Sneyd, M. J. (2012). Support for Associate Professor Barendregt’s stance against PSA testing of asymptomatic men
[Letter]. New Zealand Medical Journal, 125(1349). Retrieved from http://journal.nzma.org.nz/journal/125-1349/5043/
content.pdf.
Cox, B., & Sneyd, M. J. (2011). A regional non-melanoma skin cancer (NMSC) collection as part of the National
Cancer Registry [Letter]. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/
journal/124-1346/4981/content.pdf.
Sneyd, M. J., & Cox, B. (2011). Commentary: Decreasing response rates require investigators to quantify and report the impact
of selection bias in case-control studies. International Journal of Epidemiology, 40(5), 1355-1357. doi: 10.1093/ije/dyr123
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Commissioned Report for External Body
Sneyd, M. J., Cameron, C., & Ward, A. (2011). Sun safety and perception of risk for skin cancer [Technical report no. 55].
Commissioned by New Zealand Cancer Society. Dunedin, New Zealand: Hugh Adam Cancer Epidemiology Unit,
University of Otago. 19p.
Dunedin School of Medicine
Injury Prevention Research Unit, Preventive and Social Medicine
Chapter in Book - Research
Butler, M. (2012). Ethical reasoning: Internal and external morality for occupational therapists. In L. Robertson (Ed.), Clinical
reasoning in occupational therapy: Controversies in practice (pp. 31-44). Chichester, UK: Wiley-Blackwell.
McBride, D., & Harcombe, H. (2012). Work related musculoskeletal pain and its management. In S. Ghosh (Ed.), Pain in
perspective (pp. 63-92). New York: Intech. doi: 10.5772/51706
Journal - Research Article
Begg, D., Sullman, M., & Samaranayaka, A. (2012). The characteristics of young pre-licensed drivers: Evidence from the New
Zealand Drivers Study. Accident Analysis & Prevention, 45, 539-546. doi: 10.1016/j.aap.2011.09.006
Black, J. A., Herbison, G. P., Lyons, R. A., Polinder, S., & Derrett, S. (2011). Recovery after injury: An individual patient
data meta-analysis of general health status using the EQ-5D. Journal of Trauma, 71(4), 1003-1010. doi: 10.1097/
TA.0b013e3182238833
Cammock, R. D., Derrett, S., Davie, G., Langley, J., & Sopoaga, F. (2012). Injury to Pacific people in New Zealand: Pre-injury
characteristics and early health outcomes: Results from a cohort study. Australasian Epidemiologist, 19(2), 17-21.
Chalmers, D. J., Samaranayaka, A., Gulliver, P., & McNoe, B. (2012). Risk factors for injury in rugby union football in New
Zealand: A cohort study. British Journal of Sports Medicine, 46(2), 95-102. doi: 10.1136/bjsports-2011-090272
Coggon, D., Ntani, G., Palmer, K. T., Felli, V. E., Harari, R., Barrero, L. H., … Harcombe, H., … Derrett, S., McBride, D.,
Gray, A. (2012). The CUPID (Cultural and Psychosocial Influences on Disability) study: Methods of data collection and
characteristics of study sample. PLOS ONE, 7(7), e39820. doi: 10.1371/journal.pone.0039820
Davidson, P. L., Taylor, M. C., Wilson, S. J., Walsh, K. A. J., & Kieser, J. A. (2012). Physical components of soft-tissue ballistic
wounding and their involvement in the generation of blood backspatter. Journal of Forensic Sciences. Advance online
publication. doi: 10.1111/j.1556-4029.2012.02143.x
Davidson, P. L., Wilson, S. J., Chalmers, D. J., Wilson, B. D., Eager, D., & McIntosh, A. S. (2012). Analysis of energy flow during
playground surface impacts. Journal of Applied Biomechanics. Advance online publication.
Derrett, S., & Colhoun, S. (2011). Being a quantitative interviewer: Qualitatively exploring interviewers’ experiences in a
longitudinal cohort study. BMC Medical Research Methodology, 11, 165. doi: 10.1186/1471-2288-11-165
Derrett, S., Cousins, K., & Gauld, R. (2012). A messy reality: An analysis of New Zealand’s elective surgery scoring system
via media sources, 2000-2006. International Journal of Health Planning & Management. Advance online publication. doi:
10.1002/hpm.2127
Derrett, S., Samaranayaka, A., Wilson, S., Langley, J., Ameratunga, S., Cameron, I. D., Lilley, R., Wyeth, E., Davie, G. (2012).
Prevalence and predictors of sub-acute phase disability after injury among hospitalised and non-hospitalised groups: A
longitudinal cohort study. PLOS ONE, 7(9), e44909. doi: 10.1371/journal.pone.0044909
Gilbert, R., Fluke, J., O’Donnell, M., Gonzalez-Izquierdo, A., Brownell, M., Gulliver, P., … Sidebotham, P. (2012). Child
maltreatment: Variation in trends and policies in six developed countries. Lancet, 379(9817), 758-772. doi: 10.1016/s01406736(11)61087-8
Gulliver, P., Cryer, C., & Davie, G. (2012). The New Zealand serious non-fatal self-harm indicators: How valid are they for
monitoring trends? Injury Prevention, 18(4), 246-252. doi: 10.1136/injuryprev-2011-040081
Horsburgh, S., & Langley, J. D. (2011). Recruitment and retention of farm owners and workers for a six-month prospective
injury study in New Zealand: A feasibility study. Journal of Occupational Medicine & Toxicology, 6, 16. doi: 10.1186/17456673-6-16
Kypri, K., McCambridge, J., Vater, T., Bowe, S. J., Saunders, J. B., …, & Horton, N. J. (2012). Web-based alcohol intervention for
Maori university students: Double-blind, multi-site randomised controlled trial. Addiction. Advance online publication.
doi: 10.1111/j.1360-0443.2012.04067.x
Langley, J., Begg, D., Brookland, R., Ameratunga, S., McDowell, A., & Broughton, J. (2012). Establishment of the New
Zealand Drivers Study. New Zealand Medical Journal, 125(1357). Retrieved from http://journal.nzma.org.nz/
journal/125-1357/5239/content.pdf.
Langley, J., Begg, D., Brookland, R., Samaranayaka, A., Jordan, H., & Davie, G. (2012). Nonprogression through graduated
driver licensing: Characteristics, traffic offending, and reasons for nonprogression. Traffic Injury Prevention, 13(1), 7-13.
doi: 10.1080/15389588.2011.635170
Langley, J., Derrett, S., Davie, G., Ameratunga, S., & Wyeth, E. (2011). A cohort study of short-term functional outcomes
following injury: the role of pre-injury socio-demographic and health characteristics, injury and injury-related healthcare.
Health & Quality of Life Outcomes, 9, 68. doi: 10.1186/1477-7525-9-68
Langley, J., & Gulliver, P. (2012). A decade of serious non-fatal assault in New Zealand. New Zealand Medical Journal,
125(1363). Retrieved from http://journal.nzma.org.nz/journal/125-1363/5369/content.pdf.
176
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Lilley, R., Davie, G., Ameratunga, S., & Derrett, S. (2012). Factors predicting work status 3 months after injury: Results from
the Prospective Outcomes of Injury Study. BMJ Open, 2, e000400. doi: 10.1136/bmjopen-2011-000400
Lilley, R., Day, L., Koehncke, N., Dosman, J., Hagel, L., William, P., and for the Saskatchewan Farm Injury Cohort Study.
(2012). The relationship between fatigue-related factors and work-related injuries in the Saskatchewan Farm Injury
Cohort Study. American Journal of Industrial Medicine, 55(4), 367-375. doi: 10.1002/ajim.22003
Maclennan, B., Kypri, K., Langley, J., & Room, R. (2012). Non-response bias in a community survey of drinking, alcoholrelated experiences and public opinion on alcohol policy. Drug & Alcohol Dependence. Advance online publication. doi:
10.1016/j.drugalcdep.2012.05.014
Maclennan, B., Kypri, K., Langley, J., & Room, R. (2011). Public opinion and local government alcohol policy: A study of seven
New Zealand communities. Contemporary Drug Problems, 38, 367-386.
Maclennan, B., Kypri, K., Room, R., & Langley, J. (2012). Local government alcohol policy development: Case studies in three
New Zealand communities. Addiction. Advance online publication. doi: 10.1111/add.12017
McAllister, S., Derrett, S., Audas, R., & Paul, C. (2012). Well-being of carers of injured individuals from a prospective cohort
study in New Zealand. Australasian Epidemiologist, 19(2), 22-26.
McNoe, B. M., & Chalmers, D. J. (2011). Injury prevention behaviour in community-level soccer players. Journal of Science &
Medicine in Sport, 14(6), 482-488. doi: 10.1016/j.jsams.2011.06.002
Meier, M. H., Caspi, A., Ambler, A., Harrington, H., Houts, R., Keefe, R. S. E., McDonald, K., Ward, A., Poulton, R., Moffitt, T.
E. (2012). Persistent cannabis users show neuropsychological decline from childhood to midlife. PNAS. Advance online
publication. doi: 10.1073/pnas.1206820109
Meiklejohn, J., Connor, J., & Kypri, K. (2012). The effect of low survey response rates on estimates of alcohol consumption in a
general population survey. PLoS ONE, 7(4), e35527. doi: 10.1371/journal.pone.0035527
Meiklejohn, J., Connor, J., & Kypri, K. (2012). One in three New Zealand drinkers reports being harmed by their own
drinking in the past year. New Zealand Medical Journal, 125(1360). Retrieved from http://journal.nzma.org.nz/
journal/125-1360/5306/content.pdf.
Mertz, K. J., Koehler, S. A., Weiss, H. B., & Williams, K. E. (2011). Autopsy report diagnoses for motor vehicle-related deaths:
How much more can they add to death certificate information? International Journal of Injury Control & Safety Promotion,
18(4), 331-335. doi: 10.1080/17457300.2011.575473
Miller, T. R., Furr-Holden, C. D., Lawrence, B. A., & Weiss, H. B. (2012). Suicide deaths and nonfatal hospital admissions
for deliberate self-harm in the United States: Temporality by day of week and month of year. Crisis, 33(3), 169-177. doi:
10.1027/0227-5910/a000126
Murray, C. J. L., Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., … Derrett, S., … Grainger, R., … Merriman, T.
R., … Taylor, W. J., … Thomson, W. M., … Lopez, A. D. (2012). Disability-adjusted life years (DALYs) for 291 diseases and
injuries in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859),
2197-2223. doi: 10.1016/S0140-6736(12)61689-4
Paxton, G. A., Rice, J., Davie, G., Carapetis, J. R., & Skull, S. A. (2011). East African immigrant children in Australia have poor
immunisation coverage. Journal of Paediatrics & Child Health, 47(12), 888-892. doi: 10.1111/j.1440-1754.2011.02099.x
Polinder, S., Haagsma, J. A., Lyons, R. A., Gabbe, B. J., Ameratunga, S., Cryer, C., Derrett, S., … van Beeck, E. F. (2012). Measuring
the population burden of fatal and nonfatal injury. Epidemiologic Reviews, 34(1), 17-31. doi: 10.1093/epirev/mxr022
Psutka, R., Connor, J., Cousins, K., & Kypri, K. (2012). Sexual health, risks, and experiences of New Zealand university
students: Findings from a national cross-sectional study. New Zealand Medical Journal, 125(1361). Retrieved from http://
journal.nzma.org.nz/journal/125-1361/5321/content.pdf.
Ruffman, T., Murray, J., Halberstadt, J., & Vater, T. (2012). Age-related differences in deception. Psychology & Aging, 27(3), 543549. doi: 10.1037/a0023380
Sánchez, A. I., Villaveces, A., Krafty, R. T., Park, T., Weiss, H. B., Fabio, A., … Gutiérrez, M. I. (2011). Policies for alcohol
restriction and their association with interpersonal violence: A time-series analysis of homicides in Cali, Colombia.
International Journal of Epidemiology, 40(4), 1037-1046. doi: 10.1093/ije/dyr051
Sauber-Schatz, E. K., Armant, T. R., & Weiss, H. (2011). Injury prevention activities in Pennsylvania trauma centers. Journal of
Trauma Nursing, 18(3), 173-180. doi: 10.1097/JTN.0b013e31822b7e09
Simpson, J. C., & Nicholls, J. (2012). Preventing unintentional childhood injury at home: Injury circumstances
and interventions. International Journal of Injury Control & Safety Promotion, 19(2), 141-151. doi:
10.1080/17457300.2011.635208
Smartt, P. F. M., & Chalmers, D. J. (2012). Searching hospital discharge records for snow sport injury: No easy run?
International Journal of Injury Control & Safety Promotion, 19(2), 93-100. doi: 10.1080/17457300.2011.603146
Vladutiu, C. J., & Weiss, H. B. (2012). Motor vehicle safety during pregnancy. American Journal of Lifestyle Medicine, 6(3), 241249. doi: 10.1177/1559827611421304
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., … Derrett, S., … Grainger, R., … Merriman, T.
R., … Taylor, W. J., … Thomson, W. M., … Murray, C. J. L. (2012). Years lived with disability (YLDs) for 1160 sequelae of
289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859),
2163-2196. doi: 10.1016/S0140-6736(12)61729-2
Weiss, H. B. (2012). Maternal crash injury risk and foetal injury death in New Zealand. Australasian Epidemiologist, 19(2), 30-32.
Weiss, H. B., Sauber-Schatz, E. K., & Herring, A. H. (2011). Motor-vehicle crashes during pregnancy: A retrospective cohort
study. Open Journal of Obstetrics & Gynecology, 1, 202-207. doi: 10.4236/ojog.2011.14039
177
RESEARCH REPORT 2011/2012
Wilson, R., Derrett, S., Hansen, P., & Langley, J. D. (2012). Costs of injury in New Zealand: Accident Compensation
Corporation spending, personal spending and quality-adjusted life years lost. Injury Prevention. Advance online
publication. doi: 10.1136/injuryprev-2011-040252
Wilson, R., Derrett, S., Hansen, P., & Langley, J. (2012). Retrospective evaluation versus population norms for the measurement
of baseline health status. Health & Quality of Life Outcomes, 10, 68. doi: 10.1186/1477-7525-10-68
Journal - Research Other
Derrett, S., Beaver, C., Sullivan, M. J., Herbison, G. P., Acland, R., & Paul, C. (2012). Traumatic and non-traumatic spinal
cord impairment in New Zealand: Incidence and characteristics of people admitted to spinal units [Brief report]. Injury
Prevention. Advance online publication. doi: 10.1136/injuryprev-2011-040266
Gabbe, B. J., Lyons, R. A., Harrison, J. E., Rivara, F. P., Ameratunga, S., Jolley, D., … Derrett, S. (2012). Challenges for
measuring the burden of non-fatal injury. Australasian Epidemiologist, 19(2), 16.
Gilbert, R. E., Fluke, J., O’Donnell, M., Gonzalez-Izquierdo, A., Brownell, M., Gulliver, P., … Sidebotham, P. (2012). Trends in
child maltreatment: Authors’ reply [Letter]. Lancet, 379(9831), 2049. doi: 10.1016/S0140-6736(12)60889-7
Langley, J., & Cryer, C. (2012). A consideration of severity is sufficient to focus our prevention efforts [Commentary]. Injury
Prevention, 18(2), 73-74. doi: 10.1136/injuryprev-2011-040278
Ward, A., & Weiss, H. (2011). Mobility management for prevented, reduced, or delayed driving in teenagers (Protocol).
Cochrane Database of Systematic Reviews, 11, CD009438. doi: 10.1002/14651858.CD009438
Journal - Professional & Other Non-Research Articles
Weiss, H. B. (2012). Adolescent health and ecological determinants [Letter]. Lancet, 380(9842), 645. doi: 10.1016/s01406736(12)61363-4
Commissioned Report for External Body
Cryer, C., Gulliver, P., Langley, J., Davie, G., & Samaranayaka, A. (2011). NZIPS serious injury case definition review: The
New Zealand Injury Prevention Strategy Serious Injury Outcome Indicators: Does the case definition of serious non-fatal
injury miss a material number of serious injury cases? [Official Statistics Research Series Report]. Commissioned by Official
Statistics Research. Wellington, New Zealand: Statistics New Zealand. 38p.
Simpson, J., Purnell, M., & Samaranayaka, A. (2011). Correct use of child restraints: Methodology development. Commissioned
by Ministry of Transport. Dunedin, New Zealand: Injury Prevention Research Unit, University of Otago. 46p.
Sneyd, M. J., Cameron, C., & Ward, A. (2011). Sun safety and perception of risk for skin cancer [Technical report no. 55].
Commissioned by New Zealand Cancer Society. Dunedin, New Zealand: Hugh Adam Cancer Epidemiology Unit,
University of Otago. 19p.
Working Paper; Discussion Paper; Technical Report
Evans, J., Weiss, H., & de Graaf, B. (2011). Characteristics of at fault drivers and bicyclists involved in bicyclist motor vehicle
collisions New Zealand 2002-2009. Dunedin, New Zealand: Injury Prevention Research Unit, University of Otago. 15p.
Dunedin School of Medicine
National Poisons Centre, Preventive and Social Medicine
Journal - Research Article
Menkes, D. B., Shieffelbien, L. M., & Huthwaite, M. (2011). Hypnosedative access and risk of harm [Viewpoint]. New Zealand
Medical Journal, 124(1345). Retrieved from http://journal.nzma.org.nz/journal/124-1345/4936/content.pdf.
Schep, L. J., Knudsen, K., Slaughter, R. J., Vale, J. A., & Mégarbane, B. (2012). The clinical toxicology of gammahydroxybutyrate, gamma-butyrolactone and 1,4-butanediol. Clinical Toxicology, 50(6), 458-470. doi:
10.3109/15563650.2012.702218
Schep, L. J., Slaughter, R. J., Vale, J. A., Beasley, D. M. G., & Gee, P. (2011). The clinical toxicology of the designer
“party pills” benzylpiperazine and trifluoromethylphenylpiperazine. Clinical Toxicology, 49(3), 131-141. doi:
10.3109/15563650.2011.572076
Slaughter, R. J., Beasley, D. M. G., Lambie, B. S., Wilkins, G. T., & Schep, L. J. (2012). Poisonous plants in New Zealand: A
review of those that are most commonly enquired about to the National Poisons Centre. New Zealand Medical Journal,
125(1367). Retrieved from http://journal.nzma.org.nz/journal/125-1367/5483/content.pdf.
Journal - Research Other
McBride, D., & Schep, L. (2012). Comment on Carran and Shaw’s “New Zealand Malayan war veterans’ exposure to
dibutylphthalate” article [Letter]. New Zealand Medical Journal, 125(1361). Retrieved from http://journal.nzma.org.nz/
journal/125-1361/5337/content.pdf.
Schep, L. J., Slaughter, R. J., & Temple, W. A. (2011). Synthetic cannabinoid use in New Zealand: A brief evaluation of inquiries
to the New Zealand National Poisons Centre [Letter]. New Zealand Medical Journal, 124(1347). Retrieved from http://
journal.nzma.org.nz/journal/124-1347/5004/content.pdf.
Schep, L. J., Slaughter, R. J., Temple, W. A., & Gee, P. (2012). Comments on BZP and New Zealand’s alternative approach to
prohibition [Correspondence Letters]. Drug Testing & Analysis, 4, 57. doi: 10.1002/dta.356
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Schep, L. J., Slaughter, R. J., Temple, W. A., Lambie, B. S., Gee, P., Watts, M., & Gresham, C. (2012). Synthetic cannabinoid use
in New Zealand: A recent rebound [Letter]. New Zealand Medical Journal, 125(1364). Retrieved from http://journal.nzma.
org.nz/journal/125-1364/5391/content.pdf.
Schep, L. J., Slaughter, R. J., Temple, W. A., Nair, S. M., & Gee, P. (2011). Synthetic cannabinoid analogues: Not repeating
past mistakes [Letter]. New Zealand Medical Journal, 124(1332). Retrieved from http://journal.nzma.org.nz/
journal/124-1332/4619/content.pdf.
Woods, D. J. (2012). Guarana: Paullinia cupana, P. sorbilis also known as Brazilian cocoa and ‘Zoom’. Journal of Primary Health
Care, 4(2), 163-164.
Dunedin School of Medicine
New Zealand Pharmacovigilance Centre, Preventive and Social Medicine
Journal - Research Article
Bahri, P., & Harrison-Woolrych, M. (2012). How to improve communication for the safe use of medicines? Discussions on
social marketing and patient-tailored approaches at the annual meetings of the WHO programme for international drug
monitoring. Drug Safety, 35(12), 1073-1079. doi: 10.2165/11640530-000000000-00000
Brounéus, F., Macleod, G., Maclennan, K., Parkin, L., & Paul, C. (2012). Drug safety awareness in New Zealand: Public
knowledge and preferred sources for information. Journal of Primary Health Care, 4(4), 288-293.
Harrison-Woolrych, M., & Ashton, J. (2011). Psychiatric adverse events associated with varenicline: An intensive postmarketing
prospective cohort study in New Zealand. Drug Safety, 34(9), 763-772. doi: 10.2165/11594450-000000000-00000
Harrison-Woolrych, M., Härmark, L., Tan, M., Maggo, S., & van Grootheest, K. (2012). Epistaxis and other haemorrhagic
events associated with the smoking cessation medicine varenicline: A case series from two national pharmacovigilance
centres. European Journal of Clinical Pharmacology, 68, 1065-1072. doi: 10.1007/s00228-012-1220-y
Harrison-Woolrych, M., Maggo, S., Tan, M., Savage, R., & Ashton, J. (2012). Cardiovascular events in patients taking
varenicline: A case series from intensive postmarketing surveillance in New Zealand. Drug Safety, 35(1), 33-43. doi:
10.2165/11597690-000000000-00000
Harrison-Woolrych, M., Skegg, K., Ashton, J., Herbison, P., & Skegg, D. C. G. (2011). Nocturnal enuresis in patients taking
clozapine, risperidone, olanzapine and quetiapine: Comparative cohort study. British Journal of Psychiatry, 199(2), 140144. doi: 10.1192/bjp.bp.110.087478
Savage, R. L., Star, K., & Hill, R. (2012). Severe muscle symptoms with lipid-lowering agents may be confused with neurogenic
claudication associated with spinal canal stenosis. International Journal of Risk & Safety in Medicine, 24(4), 215-9. doi:
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Journal - Research Other
Bahri, P., & Harrison-Woolrych, M. (2012). Focusing on risk communication about medicines: Why now? [Editorial]. Drug
Safety, 35(11), 971-975. doi: 10.2165/11640990-000000000-00000
Harrison-Woolrych, M. (2012). Varenicline for smoking cessation [Editorial]. BMJ, 345, e7547. doi: 10.1136/bmj.e7547
Harrison-Woolrych, M. (2011). Patient reporting encouraged during monitoring of dapoxetine in New Zealand [Letter]. Drug
Safety, 34(11), 1115-1116. doi: 10.2165/11596010-000000000-00000
Kunac, D., Tatley, M. V., Grimwood, K., & Reith, D. M. (2012). Active surveillance of serious adverse drug reactions
in New Zealand children [Letter]. Archives of Disease in Childhood. Advance online publication. doi: 10.1136/
archdischild-2011-301457
Tan, M., & Harrison-Woolrych, M. (2012). Memory impairment associated with varenicline: A case series from the New
Zealand Intensive Medicines Monitoring Programme [Letter to the editor]. European Journal of Clinical Pharmacology.
Advance online publication. doi: 10.1007/s00228-012-1458-4
Working Paper; Discussion Paper; Technical Report
Brounéus, F., MacLennan, K., Parkin, L., Paul, C., for the University of Otago Pharmacovigilance Research Team. (2011).
Communicating drug safety information to health care professionals and the public. Health Research Council of New
Zealand, and Medsafe. Dunedin, New Zealand: University of Otago. 52p.
Dunedin School of Medicine
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Brunton, W. (2011). The medicine of the future: A history of the Department of Preventive and Social Medicine, University of
Otago, 1886-2011. Dunedin, New Zealand: Department of Preventive and Social Medicine, University of Otago, 303p.
Laugesen, M. J., & Gauld, R. (2012). Democratic governance & health: Hospitals, politics and health policy in New Zealand.
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Aspalter, C., Uchida, Y., & Gauld, R. (Eds.). (2012). Health care systems in Europe and Asia. Abingdon, UK: Routledge, 202p.
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Baxter, J., & Wyeth, E. (2011). Viewpoint: The health of Mäori children and young people with chronic conditions and
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Child and Youth Epidemiology Service.
Brunton, W. (2011). Mental health services. In Te Ara: The encyclopedia of New Zealand. Wellington, New Zealand: Ministry for
Culture and Heritage. Retrieved from http://www.teara.govt.nz/en/mental-health-services.
Connor, J. (2011). The role of driver sleepiness in car crashes: A systematic review of epidemiological studies. In J. C. Verster &
C. F. P. George (Eds.), Sleep, sleepiness and traffic safety (pp. 29-51). New York: Nova Science.
Gauld, R. (2012). The health care system in Singapore. In C. Aspalter, Y. Uchida, & R. Gauld (Eds.), Health care systems in
Europe and Asia (pp. 150-166). Abingdon, UK: Routledge.
Gauld, R. (2012). A decade of health system reforms in New Zealand. In J. Hall, J. Cumming, & M. Haas (Eds.), Celebrating
the achievements of health services research in Australia and New Zealand 2001-2011 (pp. 10-11). Ultimo, Australia: Health
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Gauld, R. (2011). The New Zealand health care system, 2011. In S. Thomson, R. Osborn, D. Squires, & S. J. Reed (Eds.),
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Gauld, R., Aspalter, C., & Uchida, Y. (2012). Introduction. In C. Aspalter, Y. Uchida, & R. Gauld (Eds.), Health care systems in
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perspective (pp. 63-92). New York: Intech. doi: 10.5772/51706
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Egan, R. (2012). Psychosocial/spirituality. In R. MacLeod, J. Vella-Brincat, & S. Macleod (Eds.), The palliative care handbook:
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Adetifa, I. M. O., Ota, M. O. C., Jeffries, D. J., Lugos, M. D., Hammond, A. S., Battersby, N. J., … Hill, P. C. (2012). Interferon
gamma ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: A clinical trial. American Journal of
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Al-Freah, M. A. B., Gane, E. J., Livingstone, V., McCall, J., & Munn, S. (2012). The effect of changes of model for end-stage liver
disease score during waiting time on post-liver transplant mortality. Hepatology International, 6(2), 491-497. doi: 10.1007/
s12072-011-9287-6
Al-Mahrouqi, H., Parkin, L., & Sharples, K. (2011). Incidence of stomach cancer in Oman and the other Gulf Cooperation
Council countries. Oman Medical Journal, 26(4), 258-262. doi: 10.5001/omj.2011.62
Al-Shaqsi, S. (2011). Better be prepared than sorry: What should the New Zealand healthcare system learn from
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Al-Shaqsi, S., Al-Kashmiri, A., Al-Risi, A., & Al-Mawali, S. (2012). Sports injuries and illnesses during the second Asian Beach
Games. British Journal of Sports Medicine, 46(11), 780-787. doi: 10.1136/bjsports-2011-090852
Al-Shaqsi, S., McBride, D., Gauld, R., Al-Kashmiri, A., & Al-Harthy, A. (2011). Are we ready? Preparedness of acute care
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Alesana-Slater, J., Ritchie, S. R., Camp, T., Heffernan, H., Richardson, A., Herbison, P., & Norris, P. (2011). Methicillin-resistant
Staphylococcus aureus, Samoa, 2007-2008. Emerging Infectious Diseases, 17(6), 1023-1029. doi: 10.3201/eid1706.101083
Amer, M., Hubert, G., Sullivan, S. J., Herbison, P., Franz, E. A., & Hammond-Tooke, G. D. (2012). Reliability and diagnostic
characteristics of clinical tests of upper limb motor function. Journal of Clinical Neuroscience, 19(9), 1246-1251. doi:
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Andersen, K. N., Medaglia, R., Vatrapu, R., Henriksen, H. Z., & Gauld, R. (2011). The forgotten promise of e-government
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Baddock, S. A., Galland, B. C., Bolton, D. P. G., Williams, S. M., & Taylor, B. J. (2012). Hypoxic and hypercapnic events in
young infants during bed-sharing. Pediatrics, 130(2), 237-244. doi: 10.1542/peds.2011-3390
Baldwin, J. N., Gauld, R., & Goldfinch, S. (2012). What public servants really think of e-government. Public Management
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Barrett, P., Hale, B., & Gauld, R. (2012). Social inclusion through ageing-in-place with care? Ageing & Society, 32(3), 361-378.
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Bartlett, J. A., Ribaudo, H. J., Wallis, C. L., Aga, E., Katzenstein, D. A., Stevens, W. S., … Crump, J. A., … Kumarasamy, N.
(2012). Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited
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Baxter, M. L., & Baxter, D. G. (2011). Anthropometric characteristics of feet of soldiers in the New Zealand Army. Military
Medicine, 176(4), 438-445.
Baxter, M. L., Baycroft, C., & Baxter, G. D. (2011). Lower limb injuries in soldiers: Feasibility of reduction through
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Baxter, M. L., Ribeiro, D. C., & Milosavljevic, S. (2012). Do orthotics work as an injury prevention strategy for the military?
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Bell, M. L., & Grunwald, G. K. (2011). Small sample estimation properties of longitudinal count models. Journal of Statistical
Computation & Simulation, 81(9), 1067-1079. doi: 10.1080/00949651003674144
Belsky, J., Hancox, R. J., Sligo, J., & Poulton, R. (2012). Does being an older parent attenuate the intergenerational transmission
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Biggs, H. M., Bui, D. M., Galloway, R. L., Stoddard, R. A., Shadomy, S. V., Morrissey, A. B., … Crump, J. A. (2011). Leptospirosis
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Black, J. A., Herbison, G. P., Lyons, R. A., Polinder, S., & Derrett, S. (2011). Recovery after injury: An individual patient
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Bocock, C., Reeder, A. I., Perez, D., & Trevena, J. (2011). Beliefs of New Zealand doctors about integrative medicine for cancer
treatment. Integrative Cancer Therapies, 10(3), 280-288. doi: 10.1177/1534735411403476
Bonsignori, M., Hwang, K.-K., Chen, X., Tsao, C.-Y., Morris, L., Gray, E., … Crump, J. A., … Haynes, B. F. (2011). Analysis
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Bonsignori, M., Montefiori, D. C., Wu, X., Chen, X., Hwang, K.-K., Tsao, C.-Y., … Crump, J. A., … Haynes, B. F. (2012).
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Bradbury, K. E., Williams, S. M., Green, T. J., McMahon, J. A., Mann, J. I., Knight, R. G., & Skeaff, C. M. (2012). Differences in
erythrocyte folate concentrations in older adults reached steady-state within one year in a two-year, controlled, 1 mg/d
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Bradley, J., Galland, B. C., Bakker, J. P., Tan, E., Gray, A., Taylor, B. J., & Dawes, P. J. D. (2012). Pulse transit time and assessment
of childhood sleep disordered breathing. Archives of Otolaryngology, 138(4), 398-403. doi: 10.1001/archoto.2012.86
Broadbent, J. M., Thomson, W. M., Boyens, J. V., & Poulton, R. (2011). Dental plaque and oral health during the first 32 years
of life. Journal of the American Dental Association, 142(4), 415-426.
Brooking, L. A., Williams, S. M., & Mann, J. I. (2012). Effects of macronutrient composition of the diet on body fat in
indigenous people at high risk of type 2 diabetes. Diabetes Research & Clinical Practice, 96(1), 40-46. doi: 10.1016/j.
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Brookland, R., & Begg, D. (2011). Adolescent, and their parents, attitudes towards graduated driver licensing and subsequent
risky driving and crashes in young adulthood. Journal of Safety Research, 42(2), 109-115.
Brounéus, F., Macleod, G., Maclennan, K., Parkin, L., & Paul, C. (2012). Drug safety awareness in New Zealand: Public
knowledge and preferred sources for information. Journal of Primary Health Care, 4(4), 288-293.
Buchanan, A. M., Nadjm, B., Amos, B., Mtove, G., Sifuna, D., Cunningham, C. K., Crump, J. A., Reyburn, H. (2012). Utility of
rapid antibody tests to exclude HIV-1 infection among infants and children aged <18 months in a low-resource setting.
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Butler, M. P., Derrett, S., & Colhoun, S. (2011). The lived experience of patients with uncertain medical diagnosis following a
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Cammock, R. D., Derrett, S., Davie, G., Langley, J., & Sopoaga, F. (2012). Injury to Pacific people in New Zealand: Pre-injury
characteristics and early health outcomes: Results from a cohort study. Australasian Epidemiologist, 19(2), 17-21.
Carter, P. J., Taylor, B. J., Williams, S. M., & Taylor, R. W. (2011). Longitudinal analysis of sleep in relation to BMI and body fat
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Chan, W., García, J. A., Newland, H. S., Muecke, J., McGovern, S., Selva, D., … Casson, R. J. (2012). Killing two birds with
one stone: The potential effect of cataract surgery on the incidence of primary angle-closure glaucoma in a high-risk
population. Clinical & Experimental Ophthalmology, 40(4), e128-e134. doi: 10.1111/j.1442-9071.2011.02607.x
Chan, Y. M., Williams, S., Davidson, L. E., & Drummond, B. K. (2011). Orofacial and dental trauma of young children in
Dunedin, New Zealand. Dental Traumatology, 27(3), 199-202. doi: 10.1111/j.1600-9657.2011.00989.x
Chang, S. Y., Horsburgh, S., Norris, P., & Braund, R. (2011). Recruitment and retention of primary care patients into a research
study investigating medication adherence. Journal of Primary Health Care, 3(3), 204-209.
Chang, C. L., Robinson, S. C., Mills, G. D., Sullivan, G. D., Karalus, N. C., McLachlan, J. D., & Hancox, R. J. (2011). Biochemical
markers of cardiac dysfunction predict mortality in acute exacerbations of COPD. Thorax, 66(9), 764-768. doi: 10.1136/
thx.2010.155333
Chang, C. L., Sullivan, G. D., Karalus, N. C., Mills, G. D., McLachlan, J. D., & Hancox, R. J. (2011). Predicting early mortality
in acute exacerbation of chronic obstructive pulmonary disease using the CURB65 score. Respirology, 16(1), 146-151. doi:
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Cheng, A. C., Kotsimbos, T., Reynolds, A., Bowler, S. D., Brown, S. G. A., Hancox, R. J., … Kelly, P. M. (2011). Clinical
and epidemiological profile of patients with severe H1N1/09 pandemic influenza in Australia and New Zealand: An
observational cohort study. BMJ Open, 1, e000100. doi: 10.1136/bmjopen-2011-000100
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Clifton, D. C., Ramadhani, H. O., Msuya, L. J., Njau, B. N., Kinabo, G. D., Buchanan, A. M., & Crump, J. A. (2012). Predicting
mortality for paediatric inpatients where malaria is uncommon. Archives of Disease in Childhood, 97(10), 889-894. doi:
10.1136/archdischild-2012-301812
Coggon, D., Ntani, G., Palmer, K. T., Felli, V. E., Harari, R., Barrero, L. H., … Harcombe, H., … Derrett, S., McBride, D.,
Gray, A. (2012). The CUPID (Cultural and Psychosocial Influences on Disability) study: Methods of data collection and
characteristics of study sample. PLOS ONE, 7(7), e39820. doi: 10.1371/journal.pone.0039820
Collaborative Group on Hormonal Factors in Breast Cancer, including McCredie, M., Paul, C., Skegg, D. C. G., & Spears,
G. F. S. (2012). Menarche, menopause, and breast cancer risk: Individual participant meta-analysis, including 118 964
women with breast cancer from 117 epidemiological studies. Lancet Oncology, 13(11), 1141-1151. doi: 10.1016/s14702045(12)70425-4
Connor, J., & Casswell, S. (2012). Alcohol-related harm to others in New Zealand: Evidence of the burden and gaps in
knowledge. New Zealand Medical Journal, 125(1360). Retrieved from http://journal.nzma.org.nz/journal/125-1360/5308/
content.pdf.
Connor, J. L., Kypri, K., Bell, M. L., & Cousins, K. (2011). Alcohol outlet density, levels of drinking and alcohol-related harm in
New Zealand: A national study. Journal of Epidemiology & Community Health, 65, 841-846. doi: 10.1136/jech.2009.104935
Connor, J. L., Kypri, K., Bell, M. L., & Cousins, K. (2011). Alcohol involvement in aggression between intimate partners in New
Zealand: A national cross-sectional study. BMJ Open, 1, e000065. doi: 10.1136/bmjopen-2011-000065
Copland, J. A., Craw, S. M., & Herbison, P. (2012). Low-lying placenta: Who should be recalled for a follow-up scan? Journal of
Medical Imaging & Radiation Oncology, 56(2), 158-162. doi: 10.1111/j.1754-9485.2012.02350.x
Coppell, K. J., Anderson, K., Williams, S. M., Lamb, C., Farmer, V. L., & Mann, J. I. (2011). The quality of diabetes care: A
comparison between patients enrolled and not enrolled on a regional diabetes register. Primary Care Diabetes, 5(2), 131137. doi: 10.1016/j.pcd.2010.10.005
Coppell, K. J., Lee, J. E. H., Williams, S. M., & Mann, J. I. (2011). Progression of glycaemia and cardiovascular risk factors in
patients of different age groups with new type 2 diabetes over 5 years of follow-up in a diabetes quality improvement
initiative. Diabetes Research & Clinical Practice, 93(3), 357-362. doi: 10.1016/j.diabres.2011.04.021
Cox, B., & Sneyd, M. J. (2011). School milk and risk of colorectal cancer: A national case-control study. American Journal of
Epidemiology, 173(4), 394-403. doi: 10.1093/aje/kwq390
Crocombe, L. A., Broadbent, J. M., Thomson, W. M., Brennan, D. S., Slade, G. D., & Poulton, R. (2011). Dental visiting
trajectory patterns and their antecedents. Journal of Public Health Dentistry, 71(1), 23-31. doi: 10.1111/j.17527325.2010.00196.x
Crump, J. A., Medalla, F. M., Joyce, K. W., Krueger, A. L., Hoekstra, R. M., Whichard, J. M., … and the Emerging Infections
Program NARMS Working Groups. (2011). Antimicrobial resistance among invasive nontyphoidal Salmonella enterica
isolates in the United States: National Antimicrobial Resistance Monitoring System, 1996 to 2007. Antimicrobial Agents &
Chemotherapy, 55(3), 1148-1154. doi: 10.1128/aac.01333-10
Crump, J. A., Morrissey, A. B., Ramadhani, H. O., Njau, B., Maro, V. P., & Reller, L. B. (2011). Controlled comparison of BacT/
Alert MB system, manual Myco/F Lytic procedure, and Isolator 10 system for diagnosis of Mycobacterium tuberculosis
bacteremia. Journal of Clinical Microbiology, 49(8), 3054-3057. doi: 10.1128/jcm.01035-11
Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Msuya, L. J., Yang, L.-Y., Chow, S.-C., … Kinabo, G. D. (2011). Invasive
bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected children and infants in northern
Tanzania. Tropical Medicine & International Health, 16(7), 830-837. doi: 10.1111/j.1365-3156.2011.02774.x
Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Bartlett, J. A. (2012). Bacteremic
disseminated tuberculosis in sub-Saharan Africa: A prospective cohort study. Clinical Infectious Diseases, 55(2), 242-250.
doi: 10.1093/cid/cis409
Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Maro, V. P. (2011). Invasive
bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected adults and adolescents in northern
Tanzania. Clinical Infectious Diseases, 52(3), 341-348. doi: 10.1093/cid/ciq103
Crump, J. A., Tuohy, M. J., Morrissey, A. B., Ramadhani, H. O., Njau, B. N., Maro, V. P., … Procop, G. W. (2012). Performance
of nucleic acid amplification following extraction of 5 milliliters of whole blood for diagnosis of Mycobacterium
tuberculosis bacteremia. Journal of Clinical Microbiology, 50(1), 138-141. doi: 10.1128/jcm.05963-11
Cryer, C., Fingerhut, L., Segui-Gomez, M., on behalf of the ICE Injury Indicators Working Group. (2011). Injury mortality
indicators: Recommendations from the International Collaborative Effort on Injury Statistics. Injury Prevention, 17(4),
281-284. doi: 10.1136/injuryprev-2011-040037
Darlow, B. A., Phillips, A. A., & Dickson, N. P. (2011). New Zealand surveillance of neonatal vitamin K deficiency bleeding
(VKDB): 1998-2008. Journal of Paediatrics & Child Health, 47(7), 460-464. doi: 10.1111/j.1440-1754.2010.01995.x
Davie, G., Samaranayaka, A., Langley, J. D., & Barson, D. (2011). Estimating person-based injury incidence: Accuracy of
an algorithm to identify readmissions from hospital discharge data. Injury Prevention, 17(5), 338-342. doi: 10.1136/
injuryprev-2011-040090
Davis, D., Baddock, S. A., Pairman, S., Hunter, M., Benn, C., Anderson, J., … Herbison, P. (2012). Risk of severe postpartum
hemorrhage in low-risk childbearing women in New Zealand: Exploring the effect of place of birth and comparing third
stage management of labor. Birth, 39(2), 98-105. doi: 10.1111/j.1523-536X.2012.00531.x
Davis, D., Baddock, S., Pairman, S., Hunter, M., Benn, C., Wilson, D., … Herbison, P. (2011). Planned place of birth in
New Zealand: Does it affect mode of birth and intervention rates among low-risk women? Birth, 38(2), 111-119. doi:
10.1111/j.1523-536X.2010.00458.x
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Davis, D., Foureur, M., Clements, V., Brodie, P., & Herbison, P. (2012). The self reported confidence of newly graduated
midwives before and after their first year of practice in Sydney, Australia. Women & Birth, 25(3), e1-e10. doi: 10.1016/j.
wombi.2011.03.005
Derrett, S., Cousins, K., & Gauld, R. (2012). A messy reality: An analysis of New Zealand’s elective surgery scoring system
via media sources, 2000-2006. International Journal of Health Planning & Management. Advance online publication. doi:
10.1002/hpm.2127
Derrett, S., Davie, G., Ameratunga, S., Wyeth, E., Colhoun, S., Wilson, S., Samaranayaka, A., Lilley, R., Hokowhitu, B., Hansen,
P., Langley, J. (2011). Prospective Outcomes of Injury Study: Recruitment, and participant characteristics, health and
disability status. Injury Prevention, 17(6), 415-418. doi: 10.1136/injuryprev-2011-040044
Derrett, S., Samaranayaka, A., Wilson, S., Langley, J., Ameratunga, S., Cameron, I. D., Lilley, R., Wyeth, E., Davie, G. (2012).
Prevalence and predictors of sub-acute phase disability after injury among hospitalised and non-hospitalised groups: A
longitudinal cohort study. PLOS ONE, 7(9), e44909. doi: 10.1371/journal.pone.0044909
Devlin, N., Buckingham, K., Shah, K., Tsuchiya, A., Tilling, C., Wilkinson, G., & van Hout, B. (2012). A comparison of
alternative variants of the lead and lag time TTO. Health Economics. Advance online publication. doi: 10.1002/hec.2819
Devlin, N. J., Tsuchiya, A., Buckingham, K., & Tilling, C. (2011). A uniform time trade off method for states better and worse
than dead: Feasibility study of the ‘lead time’ approach. Health Economics, 20(3), 348-361. doi: 10.1002/hec.1596
Dickson, N. P., McAllister, S., Sharples, K., & Paul, C. (2012). Late presentation of HIV infection among adults in New Zealand:
2005-2010. HIV Medicine, 13(3), 182-189. doi: 10.1111/j.1468-1293.2011.00959.x
Dobbinson, S., Wakefield, M., Hill, D., Girgis, A., Aitken, J. F., Beckmann, K., Reeder, A. I., … Bowles, K.-A. (2012). Children’s
sun exposure and sun protection: Prevalence in Australia and related parental factors. Journal of the American Academy of
Dermatology, 66(6), 938-947. doi: 10.1016/j.jaad.2011.06.015
Dodd, H., Williams, S., Brown, R., & Venn, B. (2011). Calculating meal glycemic index by using measured and published food
values compared with directly measured meal glycemic index. American Journal of Clinical Nutrition, 94, 992-996. doi:
10.3945/ajcn.111.012138
Donnelly, J., Cowan, D. C., Yeoman, D. J., Lucas, S. J. E., Herbison, G. P., Thomas, K. N., Ainslie, P. N., Taylor, D. R. (2011).
Exhaled nitric oxide and pulmonary artery pressures during graded ascent to high altitude. Respiratory Physiology &
Neurobiology, 177(3), 213-217. doi: 10.1016/j.resp.2011.04.008
Duthie, J. B., Vincent, M., Herbison, G. P., Wilson, D. I., & Wilson, D. (2011). Botulinum toxin injections for adults with
overactive bladder syndrome (Review). Cochrane Database of Systematic Reviews, 12, CD005493. doi: 10.1002/14651858.
CD005493.pub3
Egan, R., MacLeod, R., Jaye, C., McGee, R., Baxter, J., & Herbison, P. (2011). What is spirituality? Evidence from a New Zealand
hospice study. Mortality, 16(4), 307-324. doi: 10.1080/13576275.2011.613267
Egere, U., Townend, J., Roca, A., Akinsanya, A., Bojang, A., Nsekpong, D., … Hill, P. C. (2012). Indirect effect of 7-valent
pneumococcal conjugate vaccine on pneumococcal carriage in newborns in rural Gambia: A randomised controlled trial.
PLOS ONE, 7(11), e49143. doi: 10.1371/journal.pone.0049143
Field, P., & Gauld, R. (2011). How do vested interests maintain outdated policy? The case of food marketing to New Zealand
children. Open Health Services & Policy Journal, 4, 30-38. doi: 10.2174/1874924001104010030
Fiorillo, S. P., Landman, K. Z., Tribble, A. C., Mtalo, A., Itemba, D. K., Ostermann, J., … Crump, J. A. (2012). Changes in HIV
risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania. AIDS
Care, 24(10), 1264-1271. doi: 10.1080/09540121.2012.658751
Freel, S. A., Picking, R. A., Ferrari, G., Ding, H., Ochsenbauer, C., Kappes, J. C., … Crump, J. A., … Tomaras, G. D. (2012).
Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication. Journal
of Virology, 86(12), 6835-6846. doi: 10.1128/jvi.00437-12
Gale, C., Skegg, K., Mullen, R., Patterson, T., & Gray, A. (2012). Thoughts of suicide and stage of recovery in patients
with schizophrenia in community mental health care. Australasian Psychiatry. Advance online publication. doi:
10.1177/1039856212449669
Galland, B. C., Taylor, B. J., Elder, D. E., & Herbison, P. (2012). Normal sleep patterns in infants and children: A systematic
review of observational studies. Sleep Medicine Reviews, 16(3), 213-222. doi: 10.1016/j.smrv.2011.06.001
Galland, B. C., Tripp, E. G., Gray, A., & Taylor, B. J. (2011). Apnea-hypopnea indices and snoring in children diagnosed with
ADHD: A matched case-control study. Sleep & Breathing, 15, 455-462. doi: 10.1007/s11325-010-0357-0
Gandini, S., Boniol, M., Haukka, J., Byrnes, G., Cox, B., Sneyd, M. J., … Autier, P. (2011). Meta-analysis of observational studies
of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma. International
Journal of Cancer, 128(6), 1414-1424. doi: 10.1002/ijc.25439
Gauld, R. (2012). New Zealand’s post-2008 health system reforms: Toward re-centralization of organizational arrangements.
Health Policy, 106(2), 110-113. doi: 10.1016/j.healthpol.2012.03.018
Gauld, R. (2011). Factors associated with e-mail and internet use for health information and communications among
Australians and New Zealanders. Social Science Computer Review, 29(1), 161-171. doi: 10.1177/0894439309358239
Gauld, R. (2011). The WHO and primary healthcare reform: Mind the implementation gap. International Journal of Clinical
Practice, 65(4), 386-390. doi: 10.1111/j.1742-1241.2011.02645.x
Gauld, R., Al-Wahaibi, S., Chisholm, J., Crabbe, R., Kwon, B., Oh, T., Palepu, R., Rawcliffe, N., Sohn, S. (2011). Scorecards
for health system performance assessment: The New Zealand example. Health Policy, 103(2-3), 200-208. doi: 10.1016/j.
healthpol.2011.05.016
183
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Gauld, R., Blank, R., Burgers, J., Cohen, A. B., Dobrow, M., Ikegami, N., … Wendt, C. (2012). The World Health Report 2008:
Primary healthcare: How wide is the gap between its agenda and implementation in 12 high-income health systems?
Healthcare Policy, 7(3), 38-58.
Gauld, R., Burgers, J., Dobrow, M., Luxford, K., Minhas, R., Wendt, C., & Cohen, A. B. (2012). Quality improvement,
information technology and primary care can improve healthcare system performance. But are policy makers promoting
them? International Journal of Clinical Practice, 66(9), 827-833. doi: 10.1111/j.1742-1241.2012.02989.x
Gauld, R., Dovey, S., Tilyard, M., & Tomlin, A. (2011). How physicians can drive comparative-effectiveness research: Lessons
from New Zealand [Commentary]. American Journal of Medicine, 124(2), 93-94. doi: 10.1016/j.amjmed.2010.09.014
Gauld, R., Horsburgh, S., & Brown, J. (2011). The clinical governance development index: Results from a New Zealand study.
BMJ Quality & Safety, 20(11), 947-952. doi: 10.1136/bmjqs.2011.051482
Gauld, R., Horwitt, J., Williams, S., & Cohen, A. B. (2011). What strategies do US hospitals employ to reduce unwarranted
clinical practice variations? American Journal of Medical Quality, 26(2), 120-126. doi: 10.1177/1062860610375107
George, J., Yiannakis, M., Main, B., Devenish, R., Anderson, C., An, U. S., Williams, S. M., Gibson, R. S. (2012). Genetic
hemoglobin disorders, infection, and deficiencies of iron and vitamin A determine anemia in young Cambodian children.
Journal of Nutrition, 142(4), 781-787. doi: 10.3945/jn.111.148189
Gill, A. I., Schaughency, E., Gray, A., & Galland, B. C. (2012). Reliability of home-based physiological sleep measurements in
snoring and non-snoring 3-year olds. Sleep & Breathing. Advance online publication. doi: 10.1007/s11325-012-0663-9
Gillett, W. R., Peek, J. C., & Herbison, G. P. (2012). Development of clinical priority access criteria for assisted reproduction and
its evaluation on 1386 infertile couples in New Zealand. Human Reproduction, 27(1), 131-141. doi: 10.1093/humrep/der372
Goldfinch, S., Gauld, R., & Baldwin, N. (2011). Information and communications technology use, e-government, pain and
stress amongst public servants. New Technology, Work & Employment, 26(1), 39-53. doi: 10.1111/j.1468-005X.2010.00256.x
Goodyear-Smith, F., Gauld, R., Cumming, J., O’Keefe, B., Pert, H., & McCormack, P. (2012). International learning on
increasing the value and effectiveness of primary care (I LIVE PC) New Zealand. Journal of the American Board of Family
Medicine, 25 (Suppl. 1), S39-S44. doi: 10.3122/jabfm.2012.02.110198
Gregory, J., Thomson, W. M., Broughton, J. R., Cullinan, M. P., Seymour, G. J., Kieser, J. A., Donaghy, M.-A., Shearer, D.
M. (2012). Experiences and perceptions of oral health and oral health care among a sample of older New Zealanders.
Gerodontology, 29(1), 54-63. doi: 10.1111/j.1741-2358.2010.00402.x
Gulliver, P. J., Cryer, C., Langley, J. D., & Davie, G. S. (2011). Identifying Mäori ethnicity for estimating trends in fatal
and serious non-fatal injury. Australian & New Zealand Journal of Public Health, 35(4), 352-356. doi: 10.1111/j.17536405.2011.00730.x
Guo, H., Reeder, A. I., McGee, R., & Darling, H. (2011). Adolescents’ leisure activities, parental monitoring and cigarette
smoking: A cross-sectional study. Substance Abuse Treatment, Prevention, & Policy, 6, 12. doi: 10.1186/1747-597x-6-12
Hale, L. A., Waters, D., & Herbison, P. (2012). A randomized controlled trial to investigate the effects of water-based exercise to
improve falls risk and physical function in older adults with lower-extremity osteoarthritis. Archives of Physical Medicine &
Rehabilitation, 93(1), 27-34. doi: 10.1016/j.apmr.2011.08.004
Hancox, R. J., Cowan, D. C., Aldridge, R. E., Cowan, J. O., Palmay, R., Williamson, A., Town, G. I., Taylor, D. R. (2012). Asthma
phenotypes: Consistency of classification using induced sputum. Respirology, 17(3), 461-466. doi: 10.1111/j.14401843.2011.02113.x
Hancox, R. J., & Landhuis, C. E. (2012). Association between sleep duration and haemoglobin A1c in young adults. Journal of
Epidemiology & Community Health, 66, 957-961. doi: 10.1136/jech-2011-200217
Hancox, R. J., & Landhuis, C. E. (2011). Correlation between measures of insulin resistance in fasting and non-fasting blood.
Diabetology & Metabolic Syndrome, 3, 23. doi: 10.1186/1758-5996-3-23
Hancox, R. J., Landhuis, C. E., & Sears, M. R. (2012). Forceps birth delivery, allergic sensitisation, and asthma: A populationbased cohort study. Clinical & Experimental Allergy. Advance online publication. doi: 10.1111/j.1365-2222.2012.04058.x
Hancox, R. J., Subbarao, P., & Sears, M. R. (2012). Relevance of birth cohorts to assessment of asthma persistence. Current
Allergy & Asthma Reports, 12(3), 175-184. doi: 10.1007/s11882-012-0255-6
Harcombe, H., Derrett, S., Herbison, P., & McBride, D. (2011). ‘Do I really want to do this?’ Longitudinal cohort study
participants’ perspectives on postal survey design: A qualitative study. BMC Medical Research Methodology, 11, 8. doi:
10.1186/1471-2288-11-8
Harris, S., & Jack, S. (2011). Home-based treatment of acute malnutrition in Cambodian urban poor communities. Food &
Nutrition Bulletin, 32(4), 333-339.
Harrison-Woolrych, M., Jamieson, S., Malik, M., Holt, A., & Herbison, P. (2011). Electronic capture of dispensing data by the
New Zealand Intensive Medicines Monitoring Programme: A consultation study of community and hospital pharmacists.
International Journal of Pharmacy Practice, 19(2), 136-139. doi: 10.1111/j.2042-7174.2010.00082.x
Harrison-Woolrych, M., Skegg, K., Ashton, J., Herbison, P., & Skegg, D. C. G. (2011). Nocturnal enuresis in patients taking
clozapine, risperidone, olanzapine and quetiapine: Comparative cohort study. British Journal of Psychiatry, 199(2), 140144. doi: 10.1192/bjp.bp.110.087478
Hashim, R., Williams, S., & Thomson, W. M. (2012). Oral hygiene and dental caries in 5- to 6-year-old children in Ajman,
United Arab Emirates. International Journal of Dental Hygiene. Advance online publication. doi: 10.1111/idh.12011
Hashim, R., Williams, S., & Thomson, W. M. (2011). Severe early childhood caries and behavioural risk indicators among
young children in Ajman, United Arab Emirates. European Archives of Paediatric Dentistry, 12(4), 205-210.
184
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Haszard, J., Williams, S. M., Dawson, A. M., Skidmore, P. M. L., & Taylor, R. W. (2012). Factor analysis of the Comprehensive
Feeding Practices Questionnaire in a large sample of children. Appetite. Advance online publication. doi: 10.1016/j.
appet.2012.11.017
Hay-Smith, J., Herderschee, R., Dumoulin, C., & Herbison, P. (2012). Comparisons of approaches to pelvic floor muscle
training for urinary incontinence in women: An abridged Cochrane systematic review. European Journal of Physical &
Rehabilitation Medicine, 48(4), 689-705.
Hay-Smith, E. J. C., Herderschee, R., Dumoulin, C., & Herbison, G. P. (2011). Comparisons of approaches to pelvic floor
muscle training for urinary incontinence in women (Review). Cochrane Database of Systematic Reviews, 12, CD009508.
doi: 10.1002/14651858.cd009508
Hébert-Losier, K., Schneiders, A. G., García, J. A., Sullivan, S. J., & Simoneau, G. G. (2012). Influence of knee flexion angle and
age on triceps surae muscle fatigue during heel raises. Journal of Strength & Conditioning Research, 26(11), 3134-3147. doi:
10.1519/JSC.0b013e318243ff0e
Hébert-Losier, K., Schneiders, A. G., García, J. A., Sullivan, S. J., & Simoneau, G. G. (2012). Influence of knee flexion angle and
age on triceps surae muscle activity during heel raises. Journal of Strength & Conditioning Research, 26(11), 3124-3133. doi:
10.1519/JSC.0b013e31824435cf
Hébert-Losier, K., Schneiders, A. G., García, J. A., Sullivan, S. J., & Simoneau, G. G. (2011). Peak triceps surae muscle activity
is not specific to knee flexion angles during MVIC. Journal of Electromyography & Kinesiology, 21, 819-826. doi: 10.1016/j.
jelekin.2011.04.009
Hébert-Losier, K., Schneiders, A. G., Sullivan, S. J., Newsham-West, R. J., Garcia, J. A., & Simoneau, G. (2011). Analysis of
knee flexion angles during 2 clinical versions of the heel raise test to assess soleus and gastrocnemius function. Journal of
Orthopaedic & Sports Physical Therapy, 41(7), 505-513. doi: 10.2519/jospt.2011.3489
Herbison, P., Hay-Smith, J., & Gillespie, W. J. (2011). Meta-analyses of small numbers of trials often agree with longer-term
results. Journal of Clinical Epidemiology, 64(2), 145-153. doi: 10.1016/j.jclinepi.2010.02.017
Herbison, P., Hay-Smith, J., & Gillespie, W. J. (2011). Different methods of allocation to groups in randomized trials are
associated with different levels of bias. A meta-epidemiological study. Journal of Clinical Epidemiology, 64(10), 1070-1075.
doi: 10.1016/j.jclinepi.2010.12.018
Herderschee, R., Hay-Smith, E. J. C., Herbison, G. P., Roovers, J. P., & Heinemann, M. J. (2012). Feedback or biofeedback to
augment pelvic floor muscle training for urinary incontinence in women: Shortened version of a Cochrane systematic
review. Neurology & Urodynamics. Advance online publication. doi: 10.1002/nau.22329
Herderschee, R., Hay-Smith, E. J. C., Herbison, G. P., Roovers, J. P., & Heinemann, M. J. (2011). Feedback or biofeedback to
augment pelvic floor muscle training for urinary incontinence in women (Review). Cochrane Database of Systematic
Reviews, 7, CD009252. doi: 10.1002/14651858.cd009252
Hertz, J. T., Munishi, O. M., Ooi, E. E., Howe, S., Lim, W. Y., Chow, A., … Crump, J. A. (2012). Chikungunya and Dengue fever
among hospitalized febrile patients in Northern Tanzania. American Journal of Tropical Medicine & Hygiene, 86(1), 171177. doi: 10.4269/ajtmh.2012.11-0393
Hill, P. C., Rutherford, M. E., Audas, R., van Crevel, R., & Graham, S. M. (2011). Closing the policy-practice gap in the
management of child contacts of tuberculosis cases in developing countries. PLoS Medicine, 8(10), e1001105. doi: 10.1371/
journal.pmed.1001105
Hill, E. M., Shepherd, D., Welch, D., Dirks, K. N., & McBride, D. (2012). Perceptions of neighborhood problems and healthrelated quality of life. Journal of Community Psychology, 40(7), 814-827. doi: 10.1002/jcop.21490
Horsburgh, S., Goldfinch, S., & Gauld, R. (2011). Is public trust in government associated with trust in e-government? Social
Science Computer Review, 29(2), 232-241. doi: 10.1177/0894439310368130
Horsburgh, S., & Langley, J. D. (2011). Recruitment and retention of farm owners and workers for a six-month prospective
injury study in New Zealand: A feasibility study. Journal of Occupational Medicine & Toxicology, 6, 16. doi: 10.1186/17456673-6-16
Houghton, L. A., Gray, A. R., Rose, M. C., Miller, J. C., Hurthouse, N. A., & Gregory III, J. F. (2011). Long-term effect of
low-dose folic acid intake: Potential effect of mandatory fortification on the prevention of neural tube defects. American
Journal of Clinical Nutrition, 94(1), 136-141. doi: 10.3945/ajcn.110.004549
Houghton, L. A., Gray, A. R., Szymlek-Gay, E. A., Heath, A.-L. M., & Ferguson, E. L. (2011). Vitamin D-fortified milk achieves
the targeted serum 25-hydroxyvitamin D concentration without affecting that of parathyroid hormone in New Zealand
toddlers. Journal of Nutrition, 141(10), 1840-1846. doi: 10.3945/jn.111.145052
Hunter, D. C., Brown, R., Green, T., Thomson, C., Skeaff, M., Williams, S., … Skinner, M. A. (2012). Changes in markers
of inflammation, antioxidant capacity and oxidative stress in smokers following consumption of milk, and milk
supplemented with fruit and vegetable extracts and vitamin C. International Journal of Food Sciences & Nutrition, 63(1),
90-102. doi: 10.3109/09637486.2011.601286
Hursthouse, N. A., Gray, A. R., Miller, J. C., Rose, M. C., & Houghton, L. A. (2011). Folate status of reproductive age women
and neural tube defect risk: The effect of long-term folic acid supplementation at doses of 140 μg and 400 μg per day.
Nutrients, 3, 49-62. doi: 10.3390/nu3010049
Jack, S. J., Ou, K., Chea, M., Chhin, L., Devenish, R., Dunbar, M., … Leon de la Barra, S., Hill, P. C., Herbison, P., Gibson,
R. S. (2012). Effect of micronutrient sprinkles on reducing anemia: A cluster-randomized effectiveness trial. Archives of
Pediatrics & Adolescent Medicine, 166(9), 842-850. doi: 10.1001/archpediatrics.2012.1003
185
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Jennings, C., Harty, B., Granger, S., Wager, C., Crump, J. A., Fiscus, S. A., & Bremer, J. W. (2012). Cross-platform analysis of
HIV-1 RNA data generated by a multicenter assay validation study with wide geographic representation. Journal of Clinical
Microbiology, 50(8), 2737-2747. doi: 10.1128/jcm.00578-12
Jordan, S. R., Stevanovic, V. R., Herbison, P., Dockerty, J., & Highton, J. (2011). Methotrexate pneumonitis in rheumatoid
arthritis: Increased prevalence with increasing latitude: An epidemiological study of trends in New Zealand. Journal of
Clinical Rheumatology, 17(7), 356-357.
Kataoka, M., Venn, B. J., Williams, S. M., Te Morenga, L. A., Heemels, I. M., & Mann, J. I. (2012). Glycaemic responses to
glucose and rice in people of Chinese and European ethnicity. Diabetic Medicine. Advance online publication. doi:
10.1111/dme.12080
Keddy, K. H., Sooka, A., Letsoalo, M. E., Hoyland, G., Chaignat, C. L., Morrissey, A. B., & Crump, J. A. (2011). Sensitivity and
specificity of typhoid fever rapid antibody tests for laboratory diagnosis at two sub-Saharan African sites. Bulletin of the
World Health Organization, 89(9), 640-647. doi: 10.2471/blt.11.087627
Kelly, P. M., Kotsimbos, T., Reynolds, A., Wood-Baker, R., Hancox, B., Brown, S. G. A., … Cheng, A. C. (2011). FluCAN 2009:
Initial results from sentinel surveillance for adult influenza and pneumonia in eight Australian hospitals. Medical Journal
of Australia, 194(4), 169-174.
Kelly, H. A., Priest, P. C., Mercer, G. N., & Dowse, G. K. (2011). We should not be complacent about our population-based
public health response to the first influenza pandemic of the 21st century. BMC Public Health, 11, 78. doi: 10.1186/14712458-11-78
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193
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Waters, D. L., & Baumgartner, R. N. (2011). Sarcopenia and obesity. Clinics in Geriatric Medicine, 27(3), 401-421. doi:
10.1016/j.cger.2011.03.007
Waters, D. L., Hale, L. A., Robertson, L., Hale, B. A., & Herbison, P. (2011). Evaluation of a peer-led falls prevention program
for older adults. Archives of Physical Medicine & Rehabilitation, 92(10), 1581-1586. doi: 10.1016/j.apmr.2011.05.014
Waters, R. C., Ostermann, J., Reeves, T. D., Masnick, M. F., Thielman, N. M., Bartlett, J. A., & Crump, J. A. (2011). A costeffectiveness analysis of alternative HIV retesting strategies in sub-Saharan Africa. Journal of Acquired Immune Deficiency
Syndromes, 56(5), 443-452. doi: 10.1097/QAI.0b013e3182118f8c
Williams, S., Brian, G., & du Toit, R. (2012). Measuring vision-specific quality of life among adults in Fiji. Ophthalmic
Epidemiology, 19(6), 388-395. doi: 10.3109/09286586.2012.716896
Williams, S. M., Taylor, R. W., & Taylor, B. J. (2012). Secular changes in BMI and the associations between risk factors and BMI
in children born 29 years apart. Pediatric Obesity. Advance online publication. doi: 10.1111/j.2047-6310.2012.00081.x
Wilson, S. J., Begg, D. J., & Samaranayaka, A. (2012). Validity of using linked hospital and police traffic crash records to analyse
motorcycle injury crash characteristics. Accident Analysis & Prevention, 49, 30-35. doi: 10.1016/j.aap.2011.03.007
Wong, C.-K., & Herbison, P. (2011). Initial Q waves and outcome after reperfusion therapy in patients with ST elevation
acute myocardial infarction: A systematic review. International Journal of Cardiology, 148(3), 305-308. doi: 10.1016/j.
ijcard.2009.11.013
Wong, C.-K., Leon de la Barra, S., & Herbison, P. (2012). Role of routine early angiography post-fibrinolysis for ST elevation
myocardial infarction: A meta-regression analysis using angiography rate in the non-routine arm. International Journal of
Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.04.151
Wright, A. A., Cook, C. E., Baxter, G. D., Dockerty, J. D., & Abbott, J. H. (2011). A comparison of 3 methodological approaches
to defining major clinically important improvement of 4 performance measures in patients with hip osteoarthritis. Journal
of Orthopaedic & Sports Physical Therapy, 41(5), 319-327. doi: 10.2519/jospt.2011.3515
Wu, X., Zhou, T., Zhu, J., Zhang, B., Georgiev, I., Wang, C., … Crump, J. A., … Mascola, J. R. (2011). Focused evolution of
HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333(6049), 1593-1602. doi: 10.1126/
science.1207532
Journal - Research Other
Al-Shaqsi, S., & Stringer, M. D. (2011). Do senior medical students know enough clinical anatomy? [Letter]. New Zealand
Medical Journal, 124(1337). Retrieved from http://journal.nzma.org.nz/journal/124-1337/4743/content.pdf.
Chambers, S. T., & Dickson, N. (2011). Global polio eradication: Progress, but determination and vigilance still needed
[Viewpoint]. New Zealand Medical Journal, 124(1337). Retrieved from http://journal.nzma.org.nz/journal/124-1337/4742/
content.pdf.
Chaudhry, M., Gauld, R., & Horsburgh, S. (2012). Hospital quality-of-care performance measurement and reporting:
What New Zealand can learn from the United States and United Kingdom [Viewpoint]. New Zealand Medical Journal,
125(1366). Retrieved from http://journal.nzma.org.nz/journal/125-1366/5445/content.pdf.
Crump, J. A. (2012). Typhoid fever and the challenge of nonmalaria febrile illness in Sub-Saharan Africa [Editorial
commentary]. Clinical Infectious Diseases, 54(8), 1107-1109. doi: 10.1093/cid/cis024
Crump, J. A., Gove, S., & Parry, C. M. (2011). Management of adolescents and adults with febrile illness in resource limited
areas [Clinical review]. BMJ, 343(7819), d4847. doi: 10.1136/bmj.d4847
Crump, J. A., & Sugarman, J. (2012). Examining the scale and outcomes of global health fellowship programs in the United
States [Commentary]. Journal of Graduate Medical Education, 4(2), 261-262. doi: 10.4300/JGME-D-12-00055.1
Crump, J. A., & Sugarman, J. (2011). In response [Letter]. American Journal of Tropical Medicine & Hygiene, 84(3), 507. doi:
10.4269/ajtmh.2011.10-0694b
Crump, J. A., & Sugarman, J. (2011). Guidelines for global health training [Letter]. Health Affairs, 30(6), 1215. doi: 10.1377/
hlthaff.2011.0428
Crump, J. A., & Sugarman, J. (2011). Guidelines for international service learning programs [Letter]. Developing World
Bioethics, 11(3), 170. doi: 10.1111/j.1471-8847.2011.00315.x
Cryer, C., & Davie, G. (2011). Alcohol, ethnicity and service use in trauma patients: Challenges of presenting and interpreting
effect modification [Editorial]. Injury, 42(1), 63-65. doi: 10.1016/j.injury.2010.11.033
Cryer, C., Gulliver, P., Langley, J., Davie, G., Samaranayaka, A., & Fowler, C. (2011). A proposed theoretical definition
to address the undercounting of injury deaths [Commentary]. Injury Prevention, 17, 219-221. doi: 10.1136/
injuryprev-2011-040039
DeCamp, M., Crump, J. A., Rodriguez, J., Richardson, G., Barry, M., & Sugarman, J. (2012). Tb in a Global Health Exchange
Program [Letter]. Journal of General Internal Medicine, 27(1), 7. doi: 10.1007/s11606-011-1908-1
Derrett, S. (2011). Screening for colorectal cancer: Taking New Zealand from ‘among the worst’ to ‘the best’? [Editorial]. New
Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4587/content.pdf.
Derrett, S., Beaver, C., Sullivan, M. J., Herbison, G. P., Acland, R., & Paul, C. (2012). Traumatic and non-traumatic spinal
cord impairment in New Zealand: Incidence and characteristics of people admitted to spinal units [Brief report]. Injury
Prevention. Advance online publication. doi: 10.1136/injuryprev-2011-040266
Edwards, R., Peace, J., Hoek, J., Wilson, N., Thomson, G., & Marsh, L. (2012). Majority support among the public, youth and
smokers for retail-level controls to help end tobacco use in New Zealand [Letter]. New Zealand Medical Journal, 125(1357).
Retrieved from http://journal.nzma.org.nz/journal/125-1357/5249/content.pdf.
194
RESEARCH REPORT 2011/2012
Gale, C., Herbison, G. P., Glue, P., Coverdale, J., & Guaiana, G. (2012). Benzodizepines for generalised anxiety disorder (GAD)
(Protocol). Cochrane Database of Systematic Reviews, 11, CD001846. doi: 10.1002/14651858.CD001846.pub3
Gauld, R. (2011). Point missed [Letter]. International Journal of Clinical Practice, 65(2), 229. doi: 10.1111/j.17421241.2010.02567.x
Gauld, R. (2011). Lessons for Australian primary care reform from New Zealand, that great change laboratory [Editorial].
Medical Journal of Australia, 195(4), 216-217.
Herbison, P. (2011). Editorial comment on “Frenkl et al., Variability of urodynamic parameters in patients with overactive
bladder”. Neurourology & Urodynamics, 30(8), 1570. doi: 10.1002/nau.21077
Jick, S., Parkin, L., Hernandez, R., & Sharples, K. (2011). The pill and thrombosis: Authors’ reply [Letter]. BMJ, 342, d3347. doi:
10.1136/bmj.d3347
Kypri, K., & MacLennan, B. (2011). [Commentary on Melson et al. (2011): Pluralistic ignorance is probably real but
important questions remain about its relation to drinking and role in intervention]. Addiction, 106(6), 1085-1086. doi:
10.1111/j.1360-0443.2011.03457.x
Kypri, K., MacLennan, B., Langley, J. D., & Connor, J. L. (2011). The Alcohol Reform Bill: More tinkering than reform in
response to the New Zealand public’s demand for better liquor laws [Commentary]. Drug & Alcohol Review, 30(4), 428433. doi: 10.1111/j.1465-3362.2011.00320.x
Lofgren, S. M., Kirsch, E. J., Maro, V. P., Morrissey, A. B., Msuya, L. J., Kinabo, G. D., … Crump, J. A. (2012). Histoplasmosis
among hospitalized febrile patients in northern Tanzania. Transactions of the Royal Society of Tropical Medicine and
Hygiene, 106(8), 504-507. doi: 10.1016/j.trstmh.2012.05.009
MacLennan, B., Langley, J., & Kypri, K. (2011). Distributing surveys: Postal versus drop-and-collect [Letter to the editor].
Epidemiology, 22(3), 443-444. doi: 10.1097/EDE.0b013e3182126442
Marsh, L., McGee, R., & Gray, A. (2012). A refreshing poison: One-quarter of young New Zealand smokers choose menthol
[Letter]. Australian & New Zealand Journal of Public Health, 36(5), 495-496. doi: 10.1111/j.1753-6405.2012.00926.x
McAnally, H. M., Robertson, L. A., Strasburger, V. C., & Hancox, R. J. (2012). Bond, James Bond: A review of 46 years of
violence in films [Research letter]. Archives of Pediatrics & Adolescent Medicine. Advance online publication. doi: 10.1001/
jamapediatrics.2013.437
McBride, D. (2011). The workplace: A missing link in occupational medicine? [Editorial]. New Zealand Medical Journal,
124(1328). Retrieved from http://journal.nzma.org.nz/journal/124-1328/4513/content.pdf.
McBride, D., & Schep, L. (2012). Comment on Carran and Shaw’s “New Zealand Malayan war veterans’ exposure to
dibutylphthalate” article [Letter]. New Zealand Medical Journal, 125(1361). Retrieved from http://journal.nzma.org.nz/
journal/125-1361/5337/content.pdf.
McDowell, A., Begg, D., Connor, J., & Broughton, J. (2011). Road safety attitudes and opinions of newly licensed Mäori
car drivers: New Zealand Drivers Study [Letter]. Australian & New Zealand Journal of Public Health, 35(1), 93. doi:
10.1111/j.1753-6405.2010.00672.x
Norris, P., Choi, T., Lee, R., Lu, A., Png, C., Yang, S., & Priest, P. (2012). Adequacy of handwashing facilities in public toilets in
Dunedin, New Zealand [Letter]. Australian & New Zealand Journal of Public Health, 36(2), 194-195. doi: 10.1111/j.17536405.2012.00859.x
Parkin, L., & Paul, C. (2011). Should the AEA accept pharmaceutical industry sponsorship for annual scientific meetings and
other AEA related events: The argument against [Round Table]. Australasian Epidemiologist, 18(3), 4-5.
Reeder, A. I. (2011). Non-melanoma skin cancer [Letter]. New Zealand Medical Journal, 124(1329). Retrieved from http://
journal.nzma.org.nz/journal/124-1329/4544/content.pdf.
Schep, L. J., Slaughter, R. J., Temple, W. A., Nair, S. M., & Gee, P. (2011). Synthetic cannabinoid analogues: Not repeating
past mistakes [Letter]. New Zealand Medical Journal, 124(1332). Retrieved from http://journal.nzma.org.nz/
journal/124-1332/4619/content.pdf.
Sellman, J. D., Connor, J. L., & Robinson, G. M. (2012). Will brief interventions in primary care change the heavy drinking
culture in New Zealand? [Editorial]. New Zealand Medical Journal, 125(1354). Retrieved from http://journal.nzma.org.nz/
journal/125-1354/5184/content.pdf.
Sellman, J. D., Connor, J. L., Wells, J. E., & Joyce, P. R. (2011). The heavy drinking culture is primarily an adult issue: Not
what you read in the newspapers [Correspondence]. Australian & New Zealand Journal of Psychiatry, 45(4), 344. doi:
10.3109/00048674.2011.557650
Smith, M. D., McCall, J., Plank, L., Herbison, G. P., Soop, M., & Nygren, J. (2011). Preoperative carbohydrate treatment
for enhancing recovery after elective surgery (Protocol). Cochrane Database of Systematic Reviews, 6, CD009161. doi:
10.1002/14651858.CD009161
Sopoaga, F., Leon de la Barra, S., Van der Meer, J., Samalia, L., Carr, S., Delaibatiki, R., & Kirifi-Alai, T. N. (2011). Developing
a health workforce from an underserved population in New Zealand [Letter to the editor]. Australian & New Zealand
Journal of Public Health, 35(5), 494-495. doi: 10.1111/j.1753-6405.2011.00766.x
Venn, B., Brown, R., Dodd, H., & Williams, S. (2012). Reply to TMS Wolever and K Bhaskaran [Letter to the editor]. American
Journal of Clinical Nutrition, 95(1), 257-258. doi: 10.3945/ajcn.111.027078
Journal - Professional & Other Non-Research Articles
Chang, C. L., & Hancox, R. J. (2012). Authors’ response [Letter]. Thorax, 67(2), 178. doi: 10.1136/thoraxjnl-2011-200512
Crump, J. A. (2012). Reply to Yansouni et al [Letter]. Clinical Infectious Diseases, 55(4), 611-612. doi: 10.1093/cid/cis468
195
RESEARCH REPORT 2011/2012
Hale, L., Taylor, D., & Waters, D. (2012). Exercise is a proven fall prevention strategy: It should be embedded into usual
physiotherapy practice [Guest editorial]. New Zealand Journal of Physiotherapy, 40(2), 45-47.
Commissioned Report for External Body
Cryer, C., Gulliver, P., Davie, G., de Graaf, B., Langley, J., Boufous, S., … Steiner, C. A. (2011). Empirical validation of the New
Zealand Injury Prevention Strategy indicators: The identification of ICD diagnoses associated with a high probability of
inpatient hospital admission [Injury Prevention Research Unit, University of Otago: OR086]. Commissioned by Accident
Compensation Corporation. Dunedin, New Zealand: Injury Prevention Research Unit, University of Otago. 130p.
Lovelock, B., Lovelock, K., Jellum, C., & Thompson, A. (2011). Recent immigrants’ recreation experiences of outdoor naturebased settings in New Zealand. Commissioned by SPARC. Dunedin, New Zealand: Centre for Recreation Research,
University of Otago. 91p. Retrieved from http://www.crr.otago.ac.nz/pubs.aspx.
Parnell, W., Heath, A.-L., Brown, R., Walker, H., Gray, A., Blakey, C., Fleming, L., Turley, M., … Weerasekera, D., Templeton,
R. (2011). Methodology report for the 2008/09 New Zealand Adult Nutrition Survey. Commissioned by Ministry of Health.
Wellington, New Zealand: Ministry of Health. 79p.
Sneyd, M. J., Cameron, C., & Ward, A. (2011). Sun safety and perception of risk for skin cancer [Technical report no. 55].
Commissioned by New Zealand Cancer Society. Dunedin, New Zealand: Hugh Adam Cancer Epidemiology Unit,
University of Otago. 19p.
University of Otago, and Ministry of Health, including Parnell, W., Heath, A.-L., Brown, R., Wilson, N., Gray, A., Fleming, L.,
Thomson, C. (2011). A focus on nutrition: Key findings of the 2008/09 New Zealand Adult Nutrition Survey. Wellington,
New Zealand: Ministry of Health. 333p. Retrieved from http://www.moh.govt.nz/moh.nsf/indexmh/focus-on-nutritionsurvey-2008-09.
Exhibition
Broughton, J. (co-curator) (2011). Te Ao Mäori: Mäori Treasures from the Otago Museum, New Zealand. Shanghai Museum,
China.
Working Paper; Discussion Paper; Technical Report
Bradbury, K. E., Skeaff, C. M., Oey, I., Williams, S., & Mann, J. (2011). Monitoring voluntary fortification of bread with folic acid
[MAF Technical Paper No: 2011/103]. Wellington, New Zealand: Ministry of Agriculture and Forestry. 51p.
Brounéus, F., MacLennan, K., Parkin, L., Paul, C., for the University of Otago Pharmacovigilance Research Team. (2011).
Communicating drug safety information to health care professionals and the public. Health Research Council of New
Zealand, and Medsafe. Dunedin, New Zealand: University of Otago. 52p.
Griffiths, R., Saxton, P. J. W., Dickson, N. P., Hughes, A. J., & Rowden, J. (2011). Estimating actual HIV prevalence and
undiagnosed infection in a community sample of men who have sex with men: Methods and fieldwork in a New Zealand oral
fluid study. Dunedin, New Zealand: AIDS Epidemiology Group, University of Otago Medical School. 12p.
Lovell, S., & Lovelock, K. (2011). Mataura Community development strategy evaluation: Phase one. Dunedin, New Zealand:
Department of Preventive and Social Medicine, University of Otago. 20p.
Ludlam, A., Saxton, P., Dickson, N., & Hughes, T. (2012). The New Zealand AIDS Foundation Get it On! social marketing
campaign: Recall and understanding of the campaign message: Research brief to the Ministry of Health. Dunedin, New
Zealand: AIDS Epidemiology Group, University of Otago Medical School. 6p.
Ludlam, A., Saxton, P., Dickson, N., & Hughes, T. (2012). Attitudes towards safe sex among men who have sex with men in New
Zealand: Findings from the GAPSS and GOSS surveys 2002-2011: Research brief to the Ministry of Health. Dunedin, New
Zealand: AIDS Epidemiology Group, University of Otago Medical School. 15p.
McAllister, S., Dickson, N., & Saxton, P. (2011). HIV post-diagnosis survey: Report to the Ministry of Health. Dunedin, New
Zealand: AIDS Epidemiology Group, University of Otago Medical School. 20p.
Noble-Adams, R., Egan, R., & Blank, M.-L. (2012). Evaluation of the Cancer Connect New Zealand service. Cancer Society. 94p.
Penno, E., Audas, R., & Gauld, R. (2012). The state of the art? An analysis of New Zealand’s population-based funding formula for
health services [Technical report]. Dunedin, New Zealand: Centre for Health Systems, University of Otago. 84p.
Robertson, L., Richards, R., Egan, R., & Szymlek-Gay, E. (2011). Promotion and support of physical activity among cancer
survivors. Dunedin, New Zealand: Cancer Society Social and Behavioural Research Unit, Department of Preventive and
Social Medicine, University of Otago. 17p.
Robertson, L., Richards, R., McAnally, H., & Hancox, B. (2012). Alcohol, marketing and media: A discussion document for a
scoping study. Dunedin, New Zealand: Cancer Society Social and Behavioural Research Unit, Department of Preventive
and Social Medicine, University of Otago. 37p.
Saxton, P., Dickson, N., & Hughes, T. (2012). GAPSS 2002-2011 (Gay Auckland Periodic Sex Survey) and GOSS 2006-2011 (Gay
men’s Online Sex Survey): Basic frequencies: Report to the Ministry of Health. Auckland, New Zealand: AIDS Epidemiology
Group. 81p.
Saxton, P., Dickson, N., Ludlam, A., & Hughes, T. (2012). Condom use among gay and bisexual men in New Zealand: Findings
from the GAPSS and GOSS surveys 2002-2011: Research brief to the Ministry of Health. Dunedin, New Zealand: AIDS
Epidemiology Group, University of Otago Medical School. 9p.
Saxton, P., Dickson, N., Ludlam, A., & Hughes, T. (2012). Characteristics of men who have sex with men surveyed in sex-on-site
venues in New Zealand: Findings from the GAPSS and GOSS surveys 2002-2011: Research brief to the Ministry of Health.
Dunedin, New Zealand: AIDS Epidemiology Group, University of Otago Medical School. 9p.
196
RESEARCH REPORT 2011/2012
Other Research Output
Exhibition Catalogue
Broughton, J. R. (2011). Hei Tiki (4p.). Exhibition catalogue essay for Te Ao Mäori: Mäori Treasures from the Otago Museum,
New Zealand, Shanghai Museum, China. [Exhibition Catalogue].
Broughton, J. R. (2011). The Mäori world of New Zealand (Te Ao Mäori o Aotearoa) (6p.). Exhibition catalogue essay for Te Ao
Mäori: Mäori Treasures from the Otago Museum, New Zealand, Shanghai Museum, China. [Exhibition Catalogue].
Egan, Richard. (2011, July). Believe it or not: Spirituality does matter as we die. But is it catered for? University of Otago Winter
Lecture Series. Wellington, New Zealand. [Public Lecture].
Dunedin School of Medicine
Psychological Medicine
Chapter in Book - Research
Skegg, K. (2011). Youth suicide. In P. Gluckman & H. Hayne (Eds.), Improving the transition: Reducing social and psychological
morbidity during adolescence: A report from the Prime Minister’s Chief Science Advisor (pp. 207-216). Auckland, New
Zealand: Office of the Prime Minister’s Science Advisory Committee.
Chapter in Book - Other
Gale, C. K., & Millichamp, J. (2012). Generalised anxiety disorder. In R. Minhas (Ed.), Clinical evidence handbook: The
international source of the best available evidence for effective health care (pp. 361-363). London: BMJ Group.
Journal - Research Article
Alonso, J., Petukhova, M., Vilagut, G., Chatterji, S., Heeringa, S., Üstün, T. B., … Scott, K. M., … Kessler, R. C. (2011). Days out
of role due to common physical and mental conditions: Results from the WHO World Mental Health surveys. Molecular
Psychiatry, 16(12), 1234-1246. doi: 10.1038/mp.2010.101
Bocock, C., Reeder, A. I., Perez, D., & Trevena, J. (2011). Beliefs of New Zealand doctors about integrative medicine for cancer
treatment. Integrative Cancer Therapies, 10(3), 280-288. doi: 10.1177/1534735411403476
Brier, M. E., Gaylor, S. K., McGovren, P., Glue, P., Fang, A., & Aronoff, G. R. (2011). Pharmacokinetics of dexrazoxane in
subjects with impaired kidney function. Journal of Clinical Pharmacology, 51(5), 731-738. doi: 10.1177/0091270010369675
Bruffaerts, R., Vilagut, G., Demyttenaere, K., Alonso, J., AlHamzawi, A., Andrade, L. H., … Scott, K. M., … Kessler, R. C.
(2012). Role of common mental and physical disorders in partial disability around the world. British Journal of Psychiatry,
200(6), 454-461. doi: 10.1192/bjp.bp.111.097519
Canton, J., Scott, K., & Glue, P. (2012). Optimal treatment of social phobia: Systematic review and meta-analysis.
Neuropsychiatric Disease & Treatment, 8, 203-215. doi: 10.2147/ndt.s23317
Crawford, E., Gross, J., Brown, D., & Hayne, H. (2011). Does drawing aid communication with adolescents in interviews.
Journal of the New Zealand College of Clinical Psychologists, 21(2), 24-25.
Crawford, E., Gross, J., Patterson, T., & Hayne, H. (2012). Does children’s colour use reflect the emotional content of their
drawings? Infant & Child Development, 21(2), 198-215. doi: 10.1002/icd.742
Fernando, K., Carter, J. D., Frampton, C. M. A., Luty, S. E., McKenzie, J., Mulder, R. T., & Joyce, P. R. (2011). Childhood-,
teenage-, and adult-onset depression: Diagnostic and individual characteristics in a clinical sample. Comprehensive
Psychiatry, 52, 623-629. doi: 10.1016/j.comppsych.2010.12.006
Gale, C., Skegg, K., Mullen, R., Patterson, T., & Gray, A. (2012). Thoughts of suicide and stage of recovery in patients
with schizophrenia in community mental health care. Australasian Psychiatry. Advance online publication. doi:
10.1177/1039856212449669
Gale, C. K., Wells, J. E., McGee, M. A., & Oakley Browne, M. A. (2011). A latent class analysis of psychosis-like experiences
in the New Zealand Mental Health Survey. Acta Psychiatrica Scandinavica, 124(3), 205-213. doi: 10.1111/j.16000447.2011.01707.x
Gandelman, K., Glue, P., Laskey, R., Jones, J., LaBadie, R., & Ose, L. (2011). An eight-week trial investigating the efficacy
and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia. Pediatric
Cardiology, 32(4), 433-441. doi: 10.1007/s00246-011-9885-z
Gandelman, K., Zhu, T., Fahmi, O. A., Glue, P., Lian, K., Obach, S., & Damle, B. (2011). Unexpected effect of rifampin
on the pharmacokinetics of linezolid: In silico and in vitro approaches to explain its mechanism. Journal of Clinical
Pharmacology, 51(2), 229-236. doi: 10.1177/0091270010366445
Glue, P., Gale, C., Menkes, D. B., & Hung, N. (2012). Evaluation of bioequivalence between clozapine suspension and tablet
formulations : A multiple-dose, fed and fasted Study. Clinical Drug Investigation, 32(11), 723-727. doi: 10.1007/s40261012-0004-6
Grott Zanicotti, C., Perez, D., & Glue, P. (2012). Mood and pain responses to repeat dose intramuscular ketamine in a
depressed patient with advanced cancer. Journal of Palliative Medicine, 15(4), 400-403. doi: 10.1089/jpm.2011.0314
Gupta, S. K., Kantesaria, B., & Glue, P. (2012). Pharmacokinetics, safety, and tolerability of ribavirin in hemodialysisdependent patients. European Journal of Clinical Pharmacology, 68(4), 415-418. doi: 10.1007/s00228-011-1137-x
Harrison-Woolrych, M., Skegg, K., Ashton, J., Herbison, P., & Skegg, D. C. G. (2011). Nocturnal enuresis in patients taking
clozapine, risperidone, olanzapine and quetiapine: Comparative cohort study. British Journal of Psychiatry, 199(2), 140144. doi: 10.1192/bjp.bp.110.087478
197
RESEARCH REPORT 2011/2012
Howarth, A. M., Swain, N. R., & Treharne, G. J. (2012). First-time mothers’ perspectives on relationships with and between
midwives and doctors: Insights from a qualitative study of giving birth in New Zealand. Midwifery, 28(4), 489-494. doi:
10.1016/j.midw.2011.07.004
Howarth, A. M., Swain, N., & Treharne, G. J. (2011). Taking personal responsibility for well-being increases birth satisfaction
of first time mothers. Journal of Health Psychology, 16(8), 1221-1230. doi: 10.1177/1359105311403521
Howarth, A., Swain, N., & Treharne, G. J. (2011). First-time New Zealand mothers’ experience of birth: Importance of
relationship and support. New Zealand College of Midwives Journal, 45(45), 6-11.
Jameson, E., Trevena, J., & Swain, N. (2011). Electronic gaming as pain distraction. Pain Research & Management, 16(1), 27-32.
Karayal, O. N., Glue, P., Bachinsky, M., Stewart, M., Chappell, P., Kolluri, S., & Cavus, I. (2011). Switching from quetiapine
to ziprasidone: A sixteen-week, open-label, multicenter study evaluating the effectiveness and safety of ziprasidone in
outpatient subjects with schizophrenia or schizoaffective disorder. Journal of Psychiatric Practice, 17(2), 100-109. doi:
10.1097/01.pra.0000396061.05269.c8
Malhotra, B., Darsey, E., Crownover, P., Fang, J., & Glue, P. (2011). Comparison of pharmcokinetic variability of fesoterodine
vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. British Journal of Pharmacology,
72(2), 226-234. doi: 10.1111/j.1365-2125.2011.03948.x
Malhotra, B., Darsey, E., Crownover, P., Fang, J., & Glue, P. (2011). Comparison of pharmacokinetic variability of fesoterodine
vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. British Journal of Clinical
Pharmacology, 72(2), 226-234. doi: 10.1111/j.1365-2125.2011.03948.x
McNaughton, N., Swart, C., Neo, P., Bates, V., & Glue, P. (2012). Anti-anxiety drugs reduce conflict-specific “theta”—A
possible human anxiety-specific biomarker. Journal of Affective Disorders. Advance online publication. doi: 10.1016/j.
jad.2012.11.057
Miller, J., Shepherdson, P., & Trevena, J. (2011). Effects of clock monitoring on electroencephalographic activity:
Is unconscious movement initiation an artifact of the clock? Psychological Science, 22(1), 103-109. doi:
10.1177/0956797610391100
Nada-Raja, S., & Skegg, K. (2011). Victimization, posttraumatic stress disorder symptomatology, and later nonsuicidal selfharm in a birth cohort. Journal of Interpersonal Violence, 27(9), 3667-3681. doi: 10.1177/0886260511403757
Newton-Howes, G., & Mullen, R. (2011). Coercion in psychiatric care: Systematic review of correlates and themes. Psychiatric
Services, 62(5), 465-470. doi: 10.1176/appi.ps.62.5.465
Patterson, T., & Hayne, H. (2011). Does drawing facilitate older children’s reports of emotionally laden events? Applied
Cognitive Psychology, 25(1), 119-126. doi: 10.1002/acp.1650
Patterson, T., Mullen, R., Gale, C., & Gray, A. (2011). Compulsory community treatment and patients’ perception of recovery
in schizophrenia. Australasian Psychiatry, 19(5), 431-433. doi: 10.3109/10398562.2011.603330
Patterson, T., Rapsey, C. M., & Glue, P. (2012). Systematic review of cognitive development across childhood in Down
syndrome: Implications for treatment interventions. Journal of Intellectual Disability Research. Advance online publication.
doi: 10.1111/j.1365-2788.2012.01536.x
Quinlan, D., Swain, N., & Vella-Brodrick, D. A. (2012). Character strengths interventions: Building on what we know for
improved outcomes. Journal of Happiness Studies, 13(6), 1145-1163. doi: 10.1007/s10902-011-9311-5
Robertson, L., Skegg, K., Poore, M., Williams, S., & Taylor, B. (2012). An adolescent suicide cluster and the possible role of
electronic communication technology. Crisis, 33(4), 239-245. doi: 10.1027/0227-5910/a000140
Scott, K. M. (2011). Sex differences in the disability associated with mental disorders. Current Opinion in Psychiatry, 24(4),
331-335. doi: 10.1097/YCO.0b013e3283477ad5
Scott, K. M., & Collings, S. C. D. (2012). Gender differences in the disability (functional limitations) associated with
cardiovascular disease: A general population study. Psychosomatics, 53(1), 38-43. doi: 10.1016/j.psym.2011.05.005
Scott, K. M., Kokaua, J., & Baxter, J. (2011). Does having a chronic physical condition affect the likelihood of treatment seeking
for a mental health problem and does this vary by ethnicity. International Journal of Psychiatry in Medicine, 42(4), 421-436.
Scott, K. M., McLaughlin, K. A., Smith, D. A. R., & Ellis, P. M. (2012). Childhood maltreatment and DSM-IV adult mental
disorders: Comparison of prospective and retrospective findings. British Journal of Psychiatry, 200(6), 469-475. doi:
10.1192/bjp.bp.111.103267
Scott, K. M., Smith, D. A. R., & Ellis, P. M. (2012). A population study of childhood maltreatment and asthma diagnosis:
Differential associations between child protection database versus retrospective self-reported data. Psychosomatic Medicine.
Advance online publication. doi: 10.1097/PSY.0b013e3182648de4
Scott, K. M., Von Korff, M., Angermeyer, M. C., Benjet, C., Bruffaerts, R., de Girolamo, G., … Kessler, R. C. (2011). Association
of childhood adversities and early-onset mental disorders with adult-onset chronic physical conditions. Archives of General
Psychiatry, 68(8), 838-844. doi: 10.1001/archgenpsychiatry.2011.77
Shelker, W., Belton, A., & Glue, P. (2011). Academic performance and career choices of older medical students at the University
of Otago. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4965/
content.pdf.
Swain, N. R., Gibb, S. J., Horwood, L. J., & Fergusson, D. M. (2012). Alcohol and cannabis abuse/dependence symptoms and
life satisfaction in young adulthood. Drug & Alcohol Review, 31(3), 327-333. doi: 10.1111/j.1465-3362.2011.00339.x
Tarr, G. P., Glue, P., & Herbison, P. (2011). Comparative efficacy and acceptability of mood stabilizer and second generation
antipsychotic monotherapy for acute mania: A systematic review and meta-analysis. Journal of Affective Disorders, 134(13), 14-19. doi: 10.1016/j.jad.2010.11.009
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Tarr, G. P., Herbison, G. P., Leon de la Barra, S., & Glue, P. (2011). Study design and patient characteristics and outcome in
acute mania clinical trials. Bipolar Disorders, 13(2), 125-132. doi: 10.1111/j.1399-5618.2011.00904.x
Journal - Research Other
Gale, C., Herbison, G. P., Glue, P., Coverdale, J., & Guaiana, G. (2012). Benzodizepines for generalised anxiety disorder (GAD)
(Protocol). Cochrane Database of Systematic Reviews, 11, CD001846. doi: 10.1002/14651858.CD001846.pub3
Gale, C. K., & Millichamp, J. (2011). Generalised anxiety disorder. Clinical Evidence, 10, 1002.
Gale, C., Mullen, R., & Patterson, T. (2012). Letter to the editor. International Journal of Social Psychiatry, 58(4), 449-450. doi:
10.1177/0020764010394522
Glue, P., & Gale, C. (2011). Off-label use of quetiapine in New Zealand: A cause for concern? [Editorial]. New Zealand Medical
Journal, 124(1336). Retrieved from http://journal.nzma.org.nz/journal/124-1336/4703/content.pdf.
Glue, P., & Gale, C. (2011). [Response to the letter to the editor Off-label treatment]. New Zealand Medical Journal, 124(1338).
Retrieved from http://journal.nzma.org.nz/journal/124-1338/4774/content.pdf.
Glue, P., Gulati, A., Le Nedelec, M., & Duffull, S. (2011). Dose- and exposure-response to ketamine in depression [Letter to the
editor]. Biological Psychiatry, 70(4), e9-e10. doi: 10.1016/j.biopsych.2010.11.031
Glue, P., & Tarr, G. (2012). Comparative efficacy of anti-manic drugs in acute mania [Letter]. Lancet, 379(9819), 892. doi:
10.1016/s0140-6736(12)60388-2
Dunedin School of Medicine
Orthopaedic Surgery, Surgical Sciences
Journal - Research Article
Bennell, K. L., Egerton, T., Pua, Y.-H., Abbott, J. H., Sims, K., & Buchbinder, R. (2011). Building the rationale and structure for
a complex physical therapy intervention within the context of a clinical trial: A multimodal individualized treatment for
patients with hip osteoarthritis. Physical Therapy, 91(10), 1525-1541. doi: 10.2522/ptj.20100430
Cury Ribeiro, D., Aldabe, D., Abbott, J. H., Sole, G., & Milosavljevic, S. (2012). Dose—response relationship between workrelated cumulative postural exposure and low back pain: A systematic review. Annals of Occupational Hygiene, 56(6), 684696. doi: 10.1093/annhyg/mes003
Cury Ribeiro, D., Sole, G., Abbott, J. H., & Milosavljevic, S. (2011). Extrinsic feedback and management of low back pain: A
critical review of the literature. Manual Therapy, 16(3), 231-239. doi: 10.1016/j.math.2010.12.001
Cury Ribeiro, D., Sole, G., Abbott, J. H., & Milosavljevic, S. (2011). Cumulative postural exposure measured by a novel device:
A preliminary study. Ergonomics, 54(9), 858-865. doi: 10.1080/00140139.2011.600776
Gabel, C. P., Melloh, M., Burkett, B., & Michener, L. A. (2012). Lower Limb Functional Index: Development and clinimetric
properties. Physical Therapy, 92(1), 98-110. doi: 10.2522/ptj.20100199
Gabel, C. P., Melloh, M., Yelland, M., Burkett, B., & Roiko, A. (2011). Predictive ability of a modified Örebro Musculoskeletal
Pain Questionnaire in an acute/subacute low back pain working population. European Spine Journal, 20(3), 449-457. doi:
10.1007/s00586-010-1509-4
Gwynne Jones, D., Sims, M., & Handcock, D. (2011). Epidemiology and outcomes of acute Achilles tendon rupture with
operative or nonoperative treatment using an identical function bracing protocol. Foot & Ankle International, 32(4), 337343. doi: 10.3113/FAI.2011.0337
Hefford, C., Abbott, J. H., Arnold, R., & Baxter, G. D. (2012). The patient-specific functional scale: Validity, reliability, and
responsiveness in patients with upper extremity musculoskeletal problems. Journal of Orthopaedic & Sports Physical
Therapy, 42(2), 56-65. doi: 10.2519/jospt.2012.3953
Hefford, C., Abbott, J. H., Baxter, G. D., & Arnold, R. (2011). Outcome measurement in clinical practice: Practical and
theoretical issues for health related quality of life (HRQOL) questionnaires. Physical Therapy Reviews, 16(3), 155-167. doi:
10.1179/1743288X11Y.0000000004
Kessler, J. T., Melloh, M., Zweig, T., Aghayev, E., & Röder, C. (2011). Development of a documentation instrument for the
conservative treatment of spinal disorders in the International Spine Registry, Spine Tango. European Spine Journal, 20(3),
369-379. doi: 10.1007/s00586-010-1474-y
Kieser, D. C., Gwynne-Jones, D., & Dreyer, S. (2011). Displaced tibial intercondylar eminence fractures. Journal of Orthopaedic
Surgery, 19(3), 292-296.
Kieser, J. A., Tahere, J., Agnew, C., Kieser, D. C., Duncan, W., Swain, M. V., & Reeves, M. T. (2011). Morphoscopic analysis of
experimentally produced bony wounds from low-velocity ballistic impact. Forensic Science, Medicine, & Pathology, 7(4),
322-332. doi: 10.1007/s12024-011-9240-y
Kowalchuk Horn, K., Jennings, S., Richardson, G., van Vliet, D., Hefford, C., & Abbott, J. H. (2012). The Patient-Specific
Functional Scale: Psychometrics, clinimetrics, and application as a clinical outcome measure. Journal of Orthopaedic &
Sports Physical Therapy, 42(1), 30-42. doi: 10.2519/jospt.2012.3727
Melloh, M., Elfering, A., Egli Presland, C., Röder, C., Hendrick, P., Darlow, B., & Theis, J.-C. (2011). Predicting the transition
from acute to persistent low back pain. Occupational Medicine, 61(2), 127-131. doi: 10.1093/occmed/kqq194
Melloh, M., Elfering, A., Salathé, C. R., Käser, A., Barz, T., Röder, C., & Theis, J.-C. (2012). Predictors of sickness absence in
patients with a new episode of low back pain in primary care. Industrial Health, 50(4), 288-298. doi: 10.2486/indhealth.
MS1335
199
RESEARCH REPORT 2011/2012
Melloh, M., Theis, J.-C., & Beneke, R. (2012). Variability of blood lactate during and between given constant prolonged cycling
power. Journal of Sports Medicine & Physical Fitness, 52(6), 575-582.
Pinto, D., Robertson, M. C., Hansen, P., & Abbott, J. H. (2012). Cost-effectiveness of nonpharmacologic, nonsurgical
interventions for hip and/or knee osteoarthritis: Systematic review. Value in Health, 15(1), 1-12. doi: 10.1016/j.
jval.2011.09.003
Pinto, D., Robertson, M. C., Hansen, P., & Abbott, J. H. (2011). Good agreement between questionnaire and administrative
databases for health care use and costs in patients with osteoarthritis. BMC Medical Research Methodology, 11, 45. doi:
10.1186/1471-2288-11-45
Pinto, D., Robertson, M. C., Hansen, P., Abbott, J. H., on behalf of the MOA Trial Team. (2011). Economic evaluation within a
factorialdesign randomised controlled trial of exercise, manual therapy, or both interventions for osteoarthritis of the hip
or knee: Study protocol. BMJ Open, 1(1), e000136. doi: 10.1136/bmjopen-2011-000136
Ribeiro, D. C., Sole, G., Abbott, J. H., & Milosavljevic, S. (2011). The reliability and accuracy of an electromagnetic
motion analysis system when used conjointly with an accelerometer. Ergonomics, 54(7), 672-677. doi:
10.1080/00140139.2011.583363
Staub, L. P., Barz, T., Melloh, M., Lord, S. J., Chatfield, M., & Bossuyt, P. M. (2011). Clinical validation study to measure the
performance of the Nerve Root Sedimentation Sign for the diagnosis of lumbar spinal stenosis. Contemporary Clinical
Trials, 32(3), 470-474. doi: 10.1016/j.cct.2011.01.015
Taylor, F., Sims, M., Theis, J.-C., & Herbison, G. P. (2012). Interventions for treating acute elbow dislocations in adults
(Review). Cochrane Database of Systematic Reviews, 4, CD007908. doi: 10.1002/14651858.CD007908.pub2
Tulloch, E., Phillips, C., Sole, G., Carman, A., & Abbott, J. H. (2012). DMA clinical pilates directional-bias assessment:
Reliability and predictive validity. Journal of Orthopaedic & Sports Physical Therapy, 42(8), 676-687. doi: 10.2519/
jospt.2012.3790
Wainwright, C., Theis, J.-C., Garneti, N., & Melloh, M. (2011). Age at hip or knee joint replacement surgery predicts likelihood
of revision surgery. Journal of Bone & Joint Surgery (Br), 93-B(10), 1411-1415. doi: 10.1302/0301-620x.93b10.27100
Wright, A. A., Cook, C. E., Baxter, G. D., Dockerty, J. D., & Abbott, J. H. (2011). A comparison of 3 methodological approaches
to defining major clinically important improvement of 4 performance measures in patients with hip osteoarthritis. Journal
of Orthopaedic & Sports Physical Therapy, 41(5), 319-327. doi: 10.2519/jospt.2011.3515
Zweig, T., Aghayev, E., Melloh, M., Dietrich, D., Röder, C., & SWISSspine Registry Group. (2012). Influence of preoperative
leg pain and radiculopathy on outcomes in mono-segmental lumbar total disc replacement: Results from a nationwide
registry. European Spine Journal, 21(Suppl. 6), S729-S736. doi: 10.1007/s00586-011-1863-x
Journal - Research Other
English, J., & Theis, J.-C. (2012). Thigh pain: An unusual presentation of ruptured appendicitis [Case study]. New Zealand
Medical Journal, 125(1364). Retrieved from http://journal.nzma.org.nz/journal/125-1364/5399/content.pdf.
Kieser, D. C., Theis, J. C., & van Rij, A. M. (2011). A combined approach to the excision of sciatic notch dumb-bell tumours.
ANZ Journal of Surgery, 81(9), 650. doi: 10.1111/j.1445-2197.2011.05836.x
Melloh, M., & Barz, T. (2011). Structural LSI can occur in the absence of functional LSI [Letter]. Journal of Orthopaedic &
Sports Physical Therapy, 41(7), 534. doi: 10.2519/jospt.2011.0201
Melloh, M., Gabel, C. P., & Cuesta-Vargas, A. I. (2011). Factor analysis findings for the QuickDASH [Letter to the editor].
Spine, 36(15), 1260. doi: 10.1097/BRS.0b013e31821bbd7c
Melloh, M., Röder, C., Staub, L. P., Zweig, T., Barz, T., Theis, J.-C., & Müller, U. (2011). Randomized-controlled trials for
surgical implants: Are registries an alternative? [Guest editorial]. Orthopedics, 34(3), 161-163. doi: 10.3928/0147744720110124-03
Theis, J.-C. (2011). Musculoskeletal undergraduate curriculum: What is required? [Editorial]. New Zealand Medical Journal,
124(1335). Retrieved from http://journal.nzma.org.nz/journal/124-1335/4676/content.pdf.
Other Research Output
Melloh, M. (2011, March). The dilemma of a missing reference standard in the diagnosis of lumbar spinal stenosis. University of
Otago Department of Surgical Sciences Department Seminar, Dunedin, New Zealand. [Department Seminar].
Dunedin School of Medicine
Surgery, Surgical Sciences
Chapter in Book - Research
Jones, G. T. (2011). The pathohistology of abdominal aortic aneurysm. In R. T. Grundmann (Ed.), Diagnosis, screening and
treatment of abdominal, thoracoabdominal and thoracic aortic aneurysms (pp. 53-74). Rijeka, Croatia: InTech Europe. doi:
10.5772/746
Journal - Research Article
Ainslie, P. N., Lucas, S. J. E., Fan, J.-L., Thomas, K. N., Cotter, J. D., Tzeng, Y. C., & Burgess, K. R. (2012). Influence of
sympathoexcitation at high altitude on cerebrovascular function and ventilatory control in humans. Journal of Applied
Physiology, 113(7), 1058-1067. doi: 10.1152/japplphysiol.00463.2012
200
RESEARCH REPORT 2011/2012
Al-Freah, M. A. B., Gane, E. J., Livingstone, V., McCall, J., & Munn, S. (2012). The effect of changes of model for end-stage liver
disease score during waiting time on post-liver transplant mortality. Hepatology International, 6(2), 491-497. doi: 10.1007/
s12072-011-9287-6
Biros, E., Norman, P. E., Jones, G. T., van Rij, A. M., Yu, G., Moxon, J. V., … Golledge, J. (2011). Meta-analysis of the association
between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm. Atherosclerosis, 219,
218-223. doi: 10.1016/j.atherosclerosis.2011.07.105
Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., … CARDIoGRAM Consortium, GLOBAL
BPgen Consortium, DIAGRAM Consortium, VRCNZ Consortium, … van Rij, A., … Samani, N. J. (2011). Abdominal
aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. American Journal of
Human Genetics, 89(5), 619-627. doi: 10.1016/j.ajhg.2011.10.002
Chen-Xu, M., Topless, R., McKinney, C., Merriman, M. E., Phipps-Green, A., Dalbeth, N., … Harrison, A. A., Highton, J., …
van Rij, A., Jones, G. T., … Stamp, L. K., … Merriman, T. R. (2012). Replication of association of the interleukin 23
receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets. Annals of the Rheumatic Diseases, 71(1),
155-157. doi: 10.1136/annrheumdis-2011-200591
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2012). Plasma active
matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International
Journal of Cardiology. Advance online publication. doi: 10.1016/j.ijcard.2012.03.147
Dennis, N. A., Houghton, L. A., Jones, G. T., van Rij, A. M., Morgan, K., & McLennan, I. S. (2012). The level of serum antiMüllerian hormone correlates with vitamin D status in men and women but not in boys. Journal of Clinical Endocrinology
& Metabolism, 97(7), 2450-2455. doi: 10.1210/jc.2012-1213
Donnelly, J., Cowan, D. C., Yeoman, D. J., Lucas, S. J. E., Herbison, G. P., Thomas, K. N., Ainslie, P. N., Taylor, D. R. (2011).
Exhaled nitric oxide and pulmonary artery pressures during graded ascent to high altitude. Respiratory Physiology &
Neurobiology, 177(3), 213-217. doi: 10.1016/j.resp.2011.04.008
Donnelly, J., Lucas, S. J. E., Thomas, K. N., Galvin, S. D., & Ainslie, P. N. (2011). Profound hyperventilation and development
of periodic breathing during exceptional orthostatic stress in a 21-year-old man. Respiratory Physiology & Neurobiology,
177(1), 66-70. doi: 10.1016/j.resp.2011.02.012
Dovey, S., Hall, K., Makeham, M., Rosser, W., Kuzel, A., van Weel, C., … Phillips, R. (2011). Seeking ethical approval for an
international study in primary care patient safety. British Journal of General Practice, 61(585), e197-e204. doi: 10.3399/
bjgp11X567144
Fan, J.-L., Burgess, K. R., Thomas, K. N., Lucas, S. J. E., Cotter, J. D., Kayser, B., Peebles, K. C., Ainslie, P. N. (2012). Effects of
acetazolamide on cerebrovascular function and breathing stability at 5050m. Journal of Physiology, 590(5), 1213-1225. doi:
10.1113/jphysiol.2011.219923
Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., Kemp, R. A. (2012). Inflammatory
and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients.
International Journal of Cancer. Advance online publication. doi: 10.1002/ijc.27855
Golledge, J., Biros, E., Warrington, N., Jones, G. T., Cooper, M., van Rij, A. M., … Norman, P. E. (2011). A population-based
study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm. European Journal of Human
Genetics, 19(3), 363-366. doi: 10.1038/ejhg.2010.182
Graham, P., Martin, G., Fraser, J., Cumming, J., Williams, H., Davidson, A., … Roake, J., van Rij, A. (2012). Equity of access and
variation in general surgeons’ clinical judgements of patient priority. International Journal of Person Centered Medicine,
2(4), 883-898. doi: 10.5750/ijpcm.v2i4.298
Guidera, A. K., Dawes, P. J. D., & Stringer, M. D. (2012). Cervical fascia: A terminological pain in the neck. ANZ Journal of
Surgery, 82, 786-791. doi: 10.1111/j.1445-2197.2012.06231.x
Gunawansa, N., McCall, J. L., Holden, A., Plank, L., & Munn, S. R. (2011). Biliary complications following orthotopic liver
transplantation: A 10-year audit. HPB, 13(6), 391-399. doi: 10.1111/j.1477-2574.2011.00300.x
Harrison, S. C., Zabaneh, D., Asselbergs, F. W., Drenos, F., Jones, G. T., Shah, S., … van Rij, A. M., … Humphries, S. E. (2012).
A gene-centric study of common carotid artery remodeling. Atherosclerosis. Advance online publication. doi: 10.1016/j.
atherosclerosis.2012.11.002
Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., …
Stefansson, H. (2012). Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary
atherosclerotic burden but not with venous thromboembolism. JACC, 60(8), 722-729. doi: 10.1016/j.jacc.2012.01.078
Hollis-Moffatt, J. E., Phipps-Green, A. J., Chapman, B., Jones, G. T., van Rij, A., Gow, P. J., Harrison, A. A., Highton, J., …
Stamp, L. K., … Merriman, T. R. (2012). The renal urate transporter SLC17A1 locus: Confirmation of association with
gout. Arthritis Research & Therapy, 14(2), R92. doi: 10.1186/ar3816
Holmes, A. R., Chong, K., Rodrigues, E., Cannon, R. D., Carpenter, E., Ruske, D. R., & Dawes, P. J. D. (2012). Yeast colonization of
voice prostheses: Pilot study investigating effect of a bovine milk product containing anti-Candida albicans immunoglobulin
A antibodies on yeast colonization and valve leakage. Annals of Otology, Rhinology & Laryngology, 121(1), 61-66.
Kapustin, A., Davies, J. D., Reynolds, J. L., McNair, R., Jones, G. T., Sidibe, A., … Shanahan, C. M. (2011). Calcium regulates key
components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization. Circulation Research, 109,
e1-e12. doi: 10.1161/CIRCRESAHA.110.238808
Kardys, I., Oemrawsingh, R. M., Kay, P., Jones, G. T., McCormick, S. P. A., Daemen, J., … Serruys, P. (2012). Lipoprotein(a),
interleukin-10, C-reactive protein, and 8-year outcome after percutaneous coronary intervention. Clinical Cardiology.
Advance online publication. doi: 10.1002/clc.21988
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Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations
in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer
Research, 30, 78. doi: 10.1186/1756-9966-30-78
Krysa, J., Jones, G. T., & van Rij, A. M. (2012). Evidence for a genetic role in varicose veins and chronic venous insufficiency.
Phlebology. Advance online publication. doi: 10.1258/phleb.2011.011030
Kueh, S.-H., Livingstone, V., & Thomson, I. A. (2012). Carotid endarterectomy in octogenarians. New Zealand Medical Journal,
125(1364). Retrieved from http://journal.nzma.org.nz/journal/125-1364/5403/content.pdf.
Lee, W. G., McCall, J. L., Gane, E. J., Murphy, R., & Plank, L. D. (2012). Oral β-blockade in relation to energy expenditure in
clinically stable patients with liver cirrhosis: A double-blind randomized cross-over trial. Metabolism. Advance online
publication. doi: 10.1016/j.metabol.2012.04.001
Lees, T., Troëng, T., Thomson, I. A., Menyhei, G., Simo, G., Beiles, B., … Björck, M. (2012). International variations in
infrainguinal bypass surgery: A Vascunet report. European Journal of Vascular & Endovascular Surgery. Advance online
publication. doi: 10.1016/j.ejvs.2012.05.006
Linterman, K. S., Palmer, D. N., Kay, G. W., Barry, L. A., Mitchell, N. L., McFarlane, R. G., Black, M. A., … Hughes, S. M.
(2011). Lentiviral-mediated gene transfer to the sheep brain: Implications for gene therapy in Batten disease. Human Gene
Therapy, 22(8), 1011-1020. doi: 10.1089/hum.2011.026
Lord, I., Page, B., Thorn, M., & Thompson-Fawcett, M. (2011). Laparoscopic cholecystectomy through the umbilicus—
minimal access surgery gets more minimal. New Zealand Medical Journal, 124(1341). Retrieved from http://journal.nzma.
org.nz/journal/124-1341/4841/content.pdf.
McCall, J. (2012). Does the choice of baseline liver imaging influence patient outcome after resection of colorectal liver
metastases? HPB, 14(5), 281-282. doi: 10.1111/j.1477-2574.2012.00458.x
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2012). The orientation of the tympanic membrane [Letter to the editor].
Clinical Anatomy, 25(2), 260-262. doi: 10.1002/ca.22014
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2012). Surgical anatomy of the chorda tympani: A micro-CT study. Surgical
& Radiologic Anatomy, 34(6), 513-518. doi: 10.1007/s00276-012-0941-z
McManus, L. J., Dawes, P. J. D., & Stringer, M. D. (2011). Clinical anatomy of the chorda tympani: A systematic review. Journal
of Laryngology & Otology, 125(11), 1101-1108. doi: 10.1017/S0022215111001873
McManus, L. J., Stringer, M. D., & Dawes, P. J. D. (2012). Iatrogenic injury of the chorda tympani: A systematic review. Journal
of Laryngology & Otology, 126(1), 8-14. doi: 10.1017/S0022215111002039
Melloh, M., Eggli, S., Busato, A., & Röder, C. (2011). Predictors of early stem loosening after total hip arthroplasty: A casecontrol study. Journal of Orthopaedic Surgery, 19(3), 269-273.
Melloh, M., Elfering, A., Salathé, C. R., Käser, A., Barz, T., Röder, C., & Theis, J.-C. (2012). Predictors of sickness absence in
patients with a new episode of low back pain in primary care. Industrial Health, 50(4), 288-298. doi: 10.2486/indhealth.
MS1335
Menyhei, G., Björck, M., Beiles, B., …, Thomson, I. A., Venermo, M., & Wigger, P. (2011). Outcome following carotid
endarterectomy: Lessons learned from a large international vascular registry. European Journal of Vascular & Endovascular
Surgery, 41(6), 735-740. doi: 10.1016/j.ejvs.2011.02.028
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., Ainslie, P. N. (2011). Syncope is
unrelated to supine and postural hypotension following prolonged exercise. European Journal of Applied Physiology &
Occupational Physiology, 111(3), 469-476. doi: 10.1007/s00421-010-1671-8
Murrell, C. J., Cotter, J. D., Thomas, K. N., Lucas, S. J. E., Williams, M. J. A., & Ainslie, P. N. (2012). Cerebral blood flow and
cerebrovascular reactivity at rest and during sub-maximal exercise: Effect of age and 12-week exercise training. Age.
Advance online publication. doi: 10.1007/s11357-012-9414-x
Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic
profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring,
34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea
Pollard, M. F., Thompson-Fawcett, M. W., & Stringer, M. D. (2012). The human ileocaecal junction: Anatomical evidence of a
sphincter. Surgical & Radiologic Anatomy, 34(1), 21-29. doi: 10.1007/s00276-011-0865-z
Raj, A., McCall, J., & Gane, E. (2011). Validation of the “Metroticket” predictor in a cohort of patients transplanted
for predominantly HBV-related hepatocellular carcinoma. Journal of Hepatology, 55(5), 1063-1068. doi: 10.1016/j.
jhep.2011.01.052
Rennie, S. C., van Rij, A. M., Jaye, C., & Hall, K. H. (2011). Defining decision making: A qualitative study of international
experts’ views on surgical trainee decision making. World Journal of Surgery, 35(6), 1214-1220. doi: 10.1007/s00268-0111089-4
Richards, C. H., Campbell, V., Ho, C., Hayes, J., Elliot, T., & Thompson-Fawcett, M. (2012). Smoking is a major risk factor for
anastomotic leak in patients undergoing low anterior resection. Colorectal Disease, 14(5), 628-633. doi: 10.1111/j.14631318.2011.02718.x
Richter, K. K., Dempster, A., Tos, A. P. D., Premkumar, R., & Jackson, C. (2011). Challenging differential diagnosis of a wildtype gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational
analysis. New Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4583/
content.pdf.
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Roberts, R. L., & Barclay, M. L. (2012). Current relevance of pharmacogenetics in immunomodulation treatment for Crohn’s
disease. Journal of Gastroenterology & Hepatology, 27(10), 1546-1554. doi: 10.1111/j.1440-1746.2012.07220.x
Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction
of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi:
10.1016/j.atherosclerosis.2011.04.043
Rodger, E. J., Suetani, R. J., Jones, G. T., Kleffmann, T., Carne, A., Legge, M., & McCormick, S. P. A. (2012). Proteomic analysis
of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis.
PLoS ONE, 7(1), e30383. doi: 10.1371/journal.pone.0030383
Schunkert, H., König, I. R., Kathiresan, S., Reilly, M. P., Assimes, T. L., Holm, H., … Jones, G. T., … van Rij, A. M., … for the
CARDIoGRAM Constortium. (2011). Large-scale association analysis identifies 13 new susceptibility loci for coronary
artery disease. Nature Genetics, 43(4), 333-340. doi: 10.1038/ng.784
Sherif, A. M., Eriksson, E., Thörn, M., Vasko, J., Riklund, K., Öhberg, L., & Ljungberg, B. J. (2012). Sentinel node detection in
renal cell carcinoma. A feasibility study for detection of tumour-draining lymph nodes. BJU International, 109(8), 11341139. doi: 10.1111/j.1464-410X.2011.10444.x
Slatter, T. L., Tan, X., Yuen, Y. C., Gunningham, S., Ma, S. S., Daly, E., Packer, S., Devenish, C., Royds, J. A., Hung, N. A. (2012).
The alternative lengthening of telomeres pathway operates in non-neoplastic human cells. Journal of Pathology, 226(3),
509-518. doi: 10.1002/path.2981
Sorrenson, B., Suetani, R. J., Williams, M. J. A., Bickley, V. M., George, P. M., Jones, G. T., & McCormick, S. P. A. (2012).
Functional rescue of mutant ABCA1 proteins by sodium 4-phenylbutyrate. Journal of Lipid Research. Advance online
publication. doi: 10.1194/jlr.M027193
Tarr, G. P., Glue, P., & Herbison, P. (2011). Comparative efficacy and acceptability of mood stabilizer and second generation
antipsychotic monotherapy for acute mania: A systematic review and meta-analysis. Journal of Affective Disorders, 134(13), 14-19. doi: 10.1016/j.jad.2010.11.009
Tarr, G. P., Herbison, G. P., Leon de la Barra, S., & Glue, P. (2011). Study design and patient characteristics and outcome in
acute mania clinical trials. Bipolar Disorders, 13(2), 125-132. doi: 10.1111/j.1399-5618.2011.00904.x
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Seasonal variation and stability of
matrix metalloproteinase-9 activity and tissue inhibitor of matrix metalloproteinase-1 with storage at -80 oC. Clinical
Biochemistry, 44(16), 1346-1348. doi: 10.1016/j.clinbiochem.2011.08.1139
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Pro-MMP-9/TIMP-1 ratio correlates
poorly with a direct assessment of MMP-9 activity. Clinical Biochemistry, 44(17-18), 1480-1482. doi: 10.1016/j.
clinbiochem.2011.09.019
Tweed, M., Thompson-Fawcett, M., Schwartz, P., & Wilkinson, T. J. (2012). Determining measures of insight and
foresight from responses to multiple choice questions. Medical Teacher. Advance online publication. doi:
10.3109/0142159x.2012.733834
Tweed, M. J., Thomson-Fawcett, M., Schwartz, P., & Wilkinson, T. J. (2012). A confidence and safety approach to multiplechoice question scoring. Focus on Health Professional Education, 13(3), 84-92.
Vincent, J. R., Jones, G. T., Hill, G. B., & van Rij, A. M. (2011). Failure of microvenous valves in small superficial veins is a
key to the skin changes of venous insufficiency. Journal of Vascular Surgery, 54(6, Suppl. ), 62S-69S.e3. doi: 10.1016/j.
jvs.2011.06.085
Wainwright, C., Theis, J.-C., Garneti, N., & Melloh, M. (2011). Age at hip or knee joint replacement surgery predicts likelihood
of revision surgery. Journal of Bone & Joint Surgery (Br), 93-B(10), 1411-1415. doi: 10.1302/0301-620x.93b10.27100
Yassaie, O., Thompson-Fawcett, M., & Rossaak, J. (2012). Management of sigmoid volvulus: Is early surgery justifiable? ANZ
Journal of Surgery, 83(1-2), 74-78. doi: 10.1111/j.1445-2197.2012.06182.x
Journal - Research Other
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2011). Plasma active
matrix metalloproteinase 9 associated to diastolic dysfunction in patients with coronary artery disease [Letter].
International Journal of Cardiology, 147(2), 336-338. doi: 10.1016/j.ijcard.2010.12.093
Cornwall, J., & Melloh, M. (2012). Do New Zealand nurses claim more lumbar spine injuries than the general population? A
retrospective study (1995-2009) [Letter]. New Zealand Medical Journal, 125(1348). Retrieved from http://journal.nzma.
org.nz/journal/125-1348/5038/content.pdf.
De Maeseneer, M., Pichot, O., Cavezzi, A., Earnshaw, J., van Rij, A., Lurie, F., & Smith, P. C. (2011). Duplex ultrasound
investigation of the veins of the lower limbs after treatment for varicose veins — UIP consensus document. European
Journal of Vascular & Endovascular Surgery, 42, 89-102. doi: 10.1016/j.ejvs.2011.03.013
Ebner, F., Hanna, N., Petrich, S., & Paterson, H. (2011). Caesarean scar pregnancy at 19 weeks gestation. Australasian Journal of
Ultrasound in Medicine, 14, 31-33.
Foo, E., Williams, D., Singh, H., Bridgman, P. G., McCall, J., & Connor, S. (2012). Successful management of a large air
embolus during an extended right hepatectomy with an emergency cardiopulmonary bypass [Case report]. HPB, 14(12),
871-873. doi: 10.1111/j.1477-2574.2012.00550x
Gabel, C. P., Melloh, M., & Cuesta-Vargas, A. I. (2011). Factor structure of the neck disability index [Letter]. Spine, 36(21),
1815. doi: 10.1097/BRS.0b013e31822c0521
Glue, P., & Tarr, G. (2012). Comparative efficacy of anti-manic drugs in acute mania [Letter]. Lancet, 379(9819), 892. doi:
10.1016/s0140-6736(12)60388-2
203
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Hale, S. J. M., Hill, G. B., & Stringer, M. D. (2011). Sonographic anatomy of the subclavian vein: Does shoulder retraction
improve exposure? Anaesthesia & Intensive Care, 39(6), 1158-1160.
Kieser, D. C., Theis, J. C., & van Rij, A. M. (2011). A combined approach to the excision of sciatic notch dumb-bell tumours.
ANZ Journal of Surgery, 81(9), 650. doi: 10.1111/j.1445-2197.2011.05836.x
Macassey, E., & Dawes, P. J. D. (2011). Peritonsillar abscess [Editorial]. New Zealand Medical Journal, 124(1337). Retrieved
from http://journal.nzma.org.nz/journal/124-1337/4729/content.pdf.
Nadarasa, K., Chen, V. H. T., Galvin, S., & van der Linden, A. (2011). A large tricuspid valve mass associated with rectal
carcinoma [Clinical correspondence]. New Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.
nz/journal/124-1340/4812/content.pdf.
Richter, K. K., Premkumar, R., Yoon, H.-S., & Mercer, P. (2011). Laparoscopic adrenalectomy for a rare 14-cm adrenal
schwannoma [Case report]. Surgical Laparoscopy Endoscopy & Percutaneous Techniques, 21(6), e339-e343. doi: 10.1097/
SLE.0b013e31823ac4d4
Smith, M. D., McCall, J., Plank, L., Herbison, G. P., Soop, M., & Nygren, J. (2011). Preoperative carbohydrate treatment
for enhancing recovery after elective surgery (Protocol). Cochrane Database of Systematic Reviews, 6, CD009161. doi:
10.1002/14651858.CD009161
Journal - Professional & Other Non-Research Articles
Gabel, C. P., Michener, L. A., Melloh, M., & Burkett, B. (2012). Author response [Letter]. Physical Therapy, 92(1), 183-184. doi:
10.2522/ptj.2012.92.1.183
Stringer, M. D., & Lyall, P. (2012). Design, implementation, and evaluation of a Postgraduate Diploma in Surgical Anatomy.
Anatomical Sciences Education, 5(1), 48-54. doi: 10.1002/ase.1253
van Rij, A., & Williams, H. (2011). Public funding of bariatric surgery [Letter]. New Zealand Medical Journal, 124(1347).
Retrieved from http://journal.nzma.org.nz/journal/124-1347/5011/content.pdf.
Dunedin School of Medicine
Obstetrics & Gynaecology, Women’s & Children’s Health
Journal - Research Article
Daniels, K. R., Grace, V. M., & Gillett, W. R. (2011). Factors associated with parents’ decisions to tell their adult offspring about
the offsprings donor conception. Human Reproduction, 26(10), 2783-2790. doi: 10.1093/humrep/der247
Davis, D., Baddock, S., Pairman, S., Hunter, M., Benn, C., Wilson, D., … Herbison, P. (2011). Planned place of birth in
New Zealand: Does it affect mode of birth and intervention rates among low-risk women? Birth, 38(2), 111-119. doi:
10.1111/j.1523-536X.2010.00458.x
Duthie, J. B., Vincent, M., Herbison, G. P., Wilson, D. I., & Wilson, D. (2011). Botulinum toxin injections for adults with
overactive bladder syndrome (Review). Cochrane Database of Systematic Reviews, 12, CD005493. doi: 10.1002/14651858.
CD005493.pub3
Gillett, W. R., Peek, J. C., & Herbison, G. P. (2012). Development of clinical priority access criteria for assisted reproduction
and its evaluation on 1386 infertile couples in New Zealand. Human Reproduction, 27(1), 131-141. doi: 10.1093/humrep/
der372
Madhuvrata, P., Cody, J. D., Ellis, G., Herbison, G. P., & Hay-Smith, E. J. C. (2012). Which anticholinergic drug for overactive
bladder symptoms in adults (Review). Cochrane Database of Systematic Reviews, 1, CD005429. doi: 10.1002/14651858.
CD005429.pub2
Major, S. A., Hogan, R. J. K., Yeates, E., & Imray, C. H. E. (2012). Peripheral arterial desaturation is further exacerbated by
exercise in adolescents with acute mountain sickness. Wilderness & Environmental Medicine, 23(1), 15-23. doi: 10.1016/j.
wem.2011.12.008
MacArthur, C., Glazener, C., Lancashire, R., Herbison, P., Wilson, D., on behalf of the ProLong Study Group. (2011). Exclusive
caesarean section delivery and subsequent urinary and faecal incontinence: A 12-year longitudinal study. BJOG, 118(8),
1001-1007. doi: 10.1111/j.1471-0528.2011.02964.x
McAllum, B., Sykes, P. H. H., Sadler, L., MacNab, H., Simcock, B. J., & Mekhail, A. K. (2011). Is the treatment of CIN 2
always necessary in women under 25? American Journal of Obstetrics & Gynecology, 205(5), 478.e1-478.e7. doi: 10.1016/j.
ajog.2011.06.069
McDonald, A., Paterson, H., & Herbison, P. (2012). Registrar interest in academic obstetrics and gynaecology: A crosssectional survey. Australian & New Zealand Journal of Obstetrics & Gynaecology. Advance online publication. doi:
10.1111/j.1479-828X.2012.01468.x
Paterson, H., Kenrick, K., & Wilson, D. (2012). Teaching the Y generation obstetrics and gynaecology skills: A survey of
medical students’ thoughts on a new program. Australian & New Zealand Journal of Obstetrics & Gynaecology, 52(2), 151155. doi: 10.1111/j.1479-828X.2012.01415.x
Preston, H., & Miller, D. (2012). Final-year medical students’ perceptions of maternity care in general practice. New Zealand
Medical Journal, 125(1352). Retrieved from http://journal.nzma.org.nz/journal/125-1352/5127/content.pdf.
Slatter, T. L., Tan, X., Yuen, Y. C., Gunningham, S., Ma, S. S., Daly, E., Packer, S., Devenish, C., Royds, J. A., Hung, N. A. (2012).
The alternative lengthening of telomeres pathway operates in non-neoplastic human cells. Journal of Pathology, 226(3),
509-518. doi: 10.1002/path.2981
204
RESEARCH REPORT 2011/2012
Journal - Research Other
Ebner, F., Hanna, N., Petrich, S., & Paterson, H. (2011). Caesarean scar pregnancy at 19 weeks gestation. Australasian Journal of
Ultrasound in Medicine, 14, 31-33.
Journal - Professional & Other Non-Research Articles
Paterson, H., & Jeffs, E. (2012). Supporting women with excess maternal weight during pregnancy. Midwifery News, (March),
16-17.
Paterson, H., Klemp, D., Folland, C., & Briggs, M. (2012). Electronic maternity facility bookings. Health Care & Informatics
Review Online, 16(1), 8-11.
Dunedin School of Medicine
Paediatrics & Child Health, Women’s & Children’s Health
Edited Book - Research
Gardner, R. J. M., Sutherland, G. R., & Shaffer, L. G. (Eds.). (2011). Chromosome abnormalities and genetic counseling (4th ed.).
New York: Oxford University Press, 648p.
Chapter in Book - Research
Reith, D. (2011). Paediatric toxicology. In A. C. Moffatt, M. D. Osselton, B.Widdop, & J. Watts (Eds.), Clarke’s analysis of drugs
and poisons (Vol. 1) (4th ed.) (pp. 429-444). London: Pharmaceutical Press.
Journal - Research Article
Anderson, P., Craig, E., Jackson, G., & Jackson, C. (2012). Developing a tool to monitor potentially avoidable and ambulatory
care sensitive hospitalisations in New Zealand children. New Zealand Medical Journal, 125(1366).
Andreucci, E., Aftimos, S., Alcausin, M., Haan, E., Hunter, W., Kannu, P., … Gardner, R. J. M., … Savarirayan, R. (2011).
TRPV4 related skeletal dysplasias: A phenotypic spectrum highlighted by clinical, radiographic, and molecular studies in
21 new families. Orphanet Journal of Rare Diseases, 6(1), 37. doi: 10.1186/1750-1172-6-37
Baas, A. F., Gabbett, M., Rimac, M., Kansikas, M., Raphael, M., Nievelstein, R. A. J., … Robertson, S. P., Wimmer, K. (2012).
Agenesis of the corpus callosum and gray matter heterotopia in three patients with constitutional mismatch repair
deficiency syndrome. European Journal of Human Genetics. Advance online publication. doi: 10.1038/ejhg.2012.117
Baddock, S. A., Galland, B. C., Bolton, D. P. G., Williams, S. M., & Taylor, B. J. (2012). Hypoxic and hypercapnic events in
young infants during bed-sharing. Pediatrics, 130(2), 237-244. doi: 10.1542/peds.2011-3390
Bradley, J., Galland, B. C., Bakker, J. P., Tan, E., Gray, A., Taylor, B. J., & Dawes, P. J. D. (2012). Pulse transit time and assessment
of childhood sleep disordered breathing. Archives of Otolaryngology, 138(4), 398-403. doi: 10.1001/archoto.2012.86
Campeau, P. M., Kim, J. C., Lu, J. T., Schwartzentruber, J. A., Abdul-Rahman, O. A., Schlaubitz, S., … Robertson, S. P., … Lee,
B. H. (2012). Mutations in KAT6B, encoding a histone acetyltransferase, cause genitopatellar syndrome. American Journal
of Human Genetics, 90(2), 282-289. doi: 10.1016/j.ajhg.2011.11.023
Campeau, P. M., Lu, J. T., Dawson, B. C., Fokkema, I. F. A. C., Robertson, S. P., Gibbs, R. A., & Lee, B. H. (2012). The KAT6Brelated disorders genitopatellar syndrome and Ohdo/SBBYS syndrome have distinct clinical features reflecting distinct
molecular mechanisms. Human Mutation. Advance online publication. doi: 10.1002/humu.22141
Cardoso, S., Robertson, S. P., & Daniel, P. B. (2012). TGFBR1 mutations associated with Loeys-Dietz syndrome are
inactivating. Journal of Receptors & Signal Transduction, 32(3), 150-155. doi: 10.3109/10799893.2012.664553
Carter, P. J., Taylor, B. J., Williams, S. M., & Taylor, R. W. (2011). Longitudinal analysis of sleep in relation to BMI and body fat
in children: The FLAME study. BMJ, 342, d2712. doi: 10.1136/bmj.d2712
Craig, E., Anderson, P., Jackson, G., & Jackson, C. (2012). Measuring potentially avoidable and ambulatory care sensitive
hospitalisations in New Zealand children using a newly developed tool. New Zealand Medical Journal, 125(1366). Retrieved
from http://journal.nzma.org.nz/journal/125-1366/5442/content.pdf.
Daniel, P. B., Morgan, T., Alanay, Y., Bijlsma, E., Cho, T.-J., Cole, T., … Robertson, S. P. (2012). Disease-associated mutations
in the actin-binding domain of filamin B cause cytoplasmic focal accumulations correlating with disease severity. Human
Mutation, 33(4), 665-673. doi: 10.1002/humu.22012
Darlow, B. A., Phillips, A. A., & Dickson, N. P. (2011). New Zealand surveillance of neonatal vitamin K deficiency bleeding
(VKDB): 1998-2008. Journal of Paediatrics & Child Health, 47(7), 460-464. doi: 10.1111/j.1440-1754.2010.01995.x
Galland, B. C., Elder, D. E., & Taylor, B. J. (2012). Interventions with a sleep outcome for children with cerebral palsy or a
post-traumatic brain injury: A systematic review. Sleep Medicine Reviews. Advance online publication. doi: 10.1016/j.
smrv.2012.01.007
Galland, B. C., Kennedy, G. J., Mitchell, E. A., & Taylor, B. J. (2012). Algorithms for using an activity-based accelerometer for
identification of infant sleep-wake states during nap studies. Sleep Medicine, 13, 743-751. doi: 10.1016/j.sleep.2012.01.018
Galland, B. C., Mitchell, E. A., Thompson, J. M. D., & Wouldes, T. (2012). Auditory evoked arousal responses of 3-month-old
infants exposed to methamphetamine in utero: A nap study. Acta Paediatrica. Advance online publication. doi: 10.1111/
apa.12136
Galland, B. C., Taylor, B. J., Elder, D. E., & Herbison, P. (2012). Normal sleep patterns in infants and children: A systematic
review of observational studies. Sleep Medicine Reviews, 16(3), 213-222. doi: 10.1016/j.smrv.2011.06.001
Galland, B. C., Tripp, E. G., Gray, A., & Taylor, B. J. (2011). Apnea-hypopnea indices and snoring in children diagnosed with
ADHD: A matched case-control study. Sleep & Breathing, 15, 455-462. doi: 10.1007/s11325-010-0357-0
205
RESEARCH REPORT 2011/2012
Gay, O., Gilquin, B., Nakamura, F., Jenkins, Z. A., McCartney, R., Krakow, D., … Robertson, S. P., Baudier, J. (2011). RefilinB
(FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape. PNAS, 108(28), 1146411469. doi: 10.1073/pnas.1104211108
Gill, A. I., Schaughency, E., & Galland, B. C. (2012). Prevalence and factors associated with snoring in 3-year olds: Early links
with behavioral adjustment. Sleep Medicine. Advance online publication. doi: 10.1016/j.sleep.2012.05.007
Gill, A. I., Schaughency, E., Gray, A., & Galland, B. C. (2012). Reliability of home-based physiological sleep measurements in
snoring and non-snoring 3-year olds. Sleep & Breathing. Advance online publication. doi: 10.1007/s11325-012-0663-9
Gray, M. J., Kim, C. A., Bertola, D. R., Arantes, P. R., Stewart, H., Simpson, M. A., … Robertson, S. P. (2012). Serpentine fibula
polycystic kidney syndrome is part of the phenotypic spectrum of Hajdu-Cheney syndrome. European Journal of Human
Genetics, 20, 133-134. doi: 10.1038/ejhg.2011.125
Hardy, L. L., Hills, A. P., Timperio, A., Cliff, D., Lubans, D., Morgan, P. J., Taylor, B. J., Brown, H. (2012). A hitchhiker’s guide to
assessing sedentary behaviour among young people: Deciding what method to use. Journal of Science & Medicine in Sport.
Advance online publication. doi: 10.1016/j.jsams.2012.05.010
Haszard, J., Williams, S. M., Dawson, A. M., Skidmore, P. M. L., & Taylor, R. W. (2012). Factor analysis of the Comprehensive
Feeding Practices Questionnaire in a large sample of children. Appetite. Advance online publication. doi: 10.1016/j.
appet.2012.11.017
Holman, S. K., Daniel, P., Jenkins, Z. A., Herron, R. L., Morgan, T., Savarirayan, R., … Robertson, S. P. (2011). The male
phenotype in osteopathia striata congenita with cranial sclerosis. American Journal of Medical Genetics Part A, 155(10),
2397-2408. doi: 10.1002/ajmg.a.34178
Kerruish, N. J. (2011). Parents’ experiences of newborn screening for genetic susceptibility to type 1 diabetes. Journal of
Medical Ethics, 37(6), 348-353. doi: 10.1136/jme.2010.039206
Laue, K., Pogoda, H.-M., Daniel, P. B., van Haeringen, A., Alanay, Y., von Ameln, S., … Morgan, T., Gray, M. J., … Robertson,
S. P. (2011). Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized
degradation of retinoic acid. American Journal of Human Genetics, 89(5), 595-606. doi: 10.1016/j.ajhg.2011.09.015
Manhire, K. M., Horrocks, G., & Tangiora, A. (2012). Breastfeeding knowledge and education needs of early childhood centre
staff. Community Practitioner, 85(9), 30-33.
Mansour, S., Swinkels, M., Terhal, P. A., Wilson, L. C., Rich, P., Van Maldergem, L., … Robertson, S. P., Newbury-Ecob,
R. (2012). Van Maldergem syndrome: Further characterisation and evidence for neuronal migration abnormalities
and autosomal recessive inheritance. European Journal of Human Genetics. Advance online publication. doi: 10.1038/
ejhg.2012.57
Masurel-Paulet, A., Haan, E., Thompson, E. M., Goizet, C., Thauvin-Robinet, C., Tai, A., … Robertson, S., Faivre, L. (2011).
Lung disease associated with periventricular nodular heterotopia and an FLNA mutation. European Journal of Medical
Genetics, 54(1), 25-28. doi: 10.1016/j.ejmg.2010.09.010
McGillivray, G., Rosenfeld, J. A., Gardner, R. J. M., & Gillam, L. H. (2012). Genetic counselling and ethical issues with
chromosome microarray analysis in prenatal testing. Prenatal Diagnosis, 32(4), 389-395. doi: 10.1002/pd.3849
Medlicott, N. J., Reith, D. M., McCaffrey, F., Krittaphol, W., & Broadbent, R. S. (2012). Delayed delivery of intravenous
gentamicin in neonates: Impact of infusion variables. Journal of Pharmacy & Pharmacology. Advance online publication.
doi: 10.1111/jphp.12000
Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic
profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring,
34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea
Pisano, T., Barkovich, A. J., Leventer, R. J., Squier, W., Scheffer, I. E., Parrini, E., … Robertson, S., … Guerrini, R. (2012).
Peritrigonal and temporo-occipital heterotopia with corpus callosum and cerebellar dysgenesis. Neurology, 79(12), 12441251. doi: 10.1212/WNL.0b013e31826aac88
Ragupathy, R., Aaltonen, K., Tordoff, J., Norris, P., & Reith, D. (2012). A 3-dimensional view of access to licensed and
subsidized medicines under single-payer systems in the US, the UK, Australia and New Zealand. Pharmacoeconomics,
30(11), 1051-1065. doi: 10.2165/11595270-000000000-00000
Ragupathy, R., Tordoff, J., Norris, P., & Reith, D. (2012). Key informants’ perceptions of how PHARMAC operates in New
Zealand. International Journal of Technology Assessment in Health Care, 28(4), 367-373. doi: 10.1017/s0266462312000566
Reinstein, E., Chang, B. S., Robertson, S. P., Rimoin, D. L., & Katzir, T. (2012). Filamin A mutation associated with normal
reading skills and dyslexia in a family with periventricular heterotopia. American Journal of Medical Genetics Part A,
158A(8), 1897-1901. doi: 10.1002/ajmg.a.35455
Robertson, L., Skegg, K., Poore, M., Williams, S., & Taylor, B. (2012). An adolescent suicide cluster and the possible role of
electronic communication technology. Crisis, 33(4), 239-245. doi: 10.1027/0227-5910/a000140
Scurr, I., Wilson, L., Lees, M., Robertson, S., Kirk, E., Turner, A., … Smithson, S. (2011). Cantú syndrome: Report of nine
new cases and expansion of the clinical phenotype. American Journal of Medical Genetics Part A, 155A(3), 508-518. doi:
10.1002/ajmg.a.33885
Simpson, M. A., Irving, M. D., Asilmaz, E., Gray, M. J., Dafou, D., Elmslie, F. V., … Robertson, S. P., … Trembath, R. C. (2011).
Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss. Nature Genetics,
43(4), 303-305. doi: 10.1038/ng.779
Skidmore, D. L., Chitayat, D., Morgan, T., Hinek, A., Fischer, B., Dimopoulou, A., … Robertson, S. P. (2011). Further expansion
of the phenotypic spectrum associated with mutations in ALDH18A1, encoding Δ1-pyrroline-5-carboxylate synthase
(P5CS). American Journal of Medical Genetics Part A, 155(8), 1848-1856. doi: 10.1002/ajmg.a.34057
206
RESEARCH REPORT 2011/2012
Tan, E., Healey, D., Gray, A. R., & Galland, B. C. (2012). Sleep hygiene intervention for youth aged 10 to 18 years with
problematic sleep: A before-after pilot study. BMC Pediatrics, 12, 189. doi: 10.1186/1471-2431-12-189
Taylor, B. J., Heath, A.-L. M., Galland, B. C., Gray, A. R., Lawrence, J. A., Sayers, R. M., Dale, K., Coppell, K. J., Taylor, R. W.
(2011). Prevention of overweight in infancy (POI.nz) study: A randomised controlled trial of sleep, food and activity
interventions for preventing overweight from birth. BMC Public Health, 11, 942. doi: 10.1186/1471-2458-11-942
Taylor, R. W., Williams, S. M., Carter, P. J., Goulding, A., Gerrard, D. F., & Taylor, B. J. (2011). Changes in fat mass and fat-free
mass during the adiposity rebound: FLAME study. International Journal of Pediatric Obesity, 6(2-2), e243-e251. doi:
10.3109/17477166.2010.549488
Taylor, R. W., Williams, S. M., Grant, A. M., Taylor, B. J., & Goulding, A. (2011). Predictive ability of waist-to-height in
relation to adiposity in children is not improved with age and sex-specific values. Obesity, 19(5), 1062-1068. doi: 10.1038/
oby.2010.217
Tomlin, A., Reith, D., Dovey, S., & Tilyard, M. (2012). Methods for retrospective detection of drug safety signals and adverse
events in electronic general practice records. Drug Safety, 35(9), 733-743. doi: 10.2165/11631970-000000000-00000
Tsutsumi, S., Maekawa, A., Obata, M., Morgan, T., Robertson, S. P., & Kurachi, H. (2012). A case of boomerang dysplasia
with a novel causative mutation in filamin B: Identification of typical imaging: Findings on ultrasonography and 3D-CT
imaging. Fetal Diagnosis & Therapy. Advance online publication. doi: 10.1159/000335687
van Bon, B. W. M., Gilissen, C., Grange, D. K., Hennekam, R. C. M., Kayserili, H., Engels, H., … Robertson, S. P., … Hoischen,
A. (2012). Cantú Syndrome Is caused by mutations in ABCC9. American Journal of Human Genetics, 90(6), 1094-1101. doi:
10.1016/j.ajhg.2012.04.014
van Kogelenberg, M., Lerone, M., De Toni, T., Divizia, M. T., de Brouwer, A. P. M., Veltman, J. A., … Robertson, S. P. (2011). A
novel Xp22.11 deletion causing a syndrome of craniosynostosis and periventricular nodular heterotopia. American Journal
of Medical Genetics Part A, 155(12), 3144-3147. doi: 10.1002/ajmg.a.34311
Warman, M. L., Cormier-Daire, V., Hall, C., Krakow, D., Lachman, R., LeMerrer, M., … Robertson, S., … Superti-Furga, A.
(2011). Nosology and Classification of Genetic Skeletal Disorders: 2010 revision. American Journal of Medical Genetics Part
A, 155(5), 943-968. doi: 10.1002/ajmg.a.33909
Wheeler, B., Broadbent, R., & Reith, D. (2012). Premedication for neonatal intubation in Australia and New Zealand: A survey
of current practice. Journal of Paediatrics & Child Health, 48(11), 997-1000. doi: 10.1111/j.1440-1754.2012.02589.x
Wheeler, B. J., & Taylor, B. J. (2012). Successful management of allergy to the insulin excipient metacresol in a child with type 1
diabetes: A case report. Journal of Medical Case Reports, 6, 263. doi: 10.1186/1752-1947-6-263
Williams, S. M., Taylor, R. W., & Taylor, B. J. (2012). Secular changes in BMI and the associations between risk factors and BMI
in children born 29 years apart. Pediatric Obesity. Advance online publication. doi: 10.1111/j.2047-6310.2012.00081.x
Wilson, C., Kerruish, N. J., Wilcken, B., Wiltshire, E., Bendikson, K., & Webster, D. (2012). Diagnosis of disorders of
intermediary metabolism in New Zealand before and after expanded newborn screening: 2004-2009. New Zealand Medical
Journal, 125(1348). Retrieved from http://journal.nzma.org.nz/journal/125-1348/5019/content.pdf.
Zankl, A., Duncan, E. L., Leo, P. J., Clark, G. R., Glazova, E. A., Addor, M.-C., … Robertson, S. P., … Brown, M. A. (2012).
Multicentric carpotarsal osteolysis is caused by mutations clustering in the amino-terminal transcriptional activation
domain of MAFB. American Journal of Human Genetics, 90(3), 494-501. doi: 10.1016/j.ajhg.2012.01.003
Journal - Research Other
Barnes, J., Behrens, T. K., Benden, M. E., Biddle, S., Bond, D. R., Brown, H., … Taylor, B., … Woodruff, S. (2012). Standardized
use of the terms “sedentary” and “sedentary behaviours” [Letter to the editor]. Applied Physiology Nutrition & Metabolism,
37(3), 540-542. doi: 10.1139/h2012-024
D’Souza, A. J., Turner, N., Simmers, D., Craig, E., & Dowell, T. (2012). Every child to thrive, belong and achieve? Time to reflect
and act in New Zealand [Special article]. New Zealand Medical Journal, 125(1352). Retrieved from http://journal.nzma.
org.nz/journal/125-1352/5129/content.pdf.
Jull, A., Lawes, C. M. M., Eyles, H., Maddison, R., Gorton, D., Arcus, K., … Taylor, B., Mann, J. (2011). Clinical guidelines for
weight management in New Zealand adults, children and young people. Journal of Primary Health Care, 3(1), 66-71.
Kunac, D., Tatley, M. V., Grimwood, K., & Reith, D. M. (2012). Active surveillance of serious adverse drug reactions
in New Zealand children [Letter]. Archives of Disease in Childhood. Advance online publication. doi: 10.1136/
archdischild-2011-301457
Robertson, S. P., & Kerruish, N. (2012). Resolving the impasse on predictive genetic testing in minors: Will more evidence be
the solution? [Commentary]. Journal of Medical Ethics, 38(9), 525-526. doi: 10.1136/medethics-2012-100557
Journal - Professional & Other Non-Research Articles
Beasley, S., & Robertson, S. (2012). Re: Currarinot triade [Letter to the editor]. ANZ Journal of Surgery, 82(9), 659. doi:
10.1111/j.1445-2197.2012.06158.x
Paterson, H., & Jeffs, E. (2012). Supporting women with excess maternal weight during pregnancy. Midwifery News, (March),
16-17.
Commissioned Report for External Body
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young
people in Otago and Southland. Commissioned by Southern DHB. Dunedin, New Zealand: New Zealand Child and Youth
Epidemiology Service. 499p.
207
RESEARCH REPORT 2011/2012
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young people
in Canterbury and the West Coast. Commissioned by Canterbury and West Coast DHB. Dunedin, New Zealand: New
Zealand Child and Youth Epidemiology Service. 498p.
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young people
in the Hutt Valley and Capital and Coast DHBs. Commissioned by Hutt Valley and Capital and Coast DHBs. Dunedin, New
Zealand: New Zealand Child and Youth Epidemiology Service. 498p.
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young
people in the Hawke’s Bay. Commissioned by Hawke’s Bay DHB. Dunedin, New Zealand: New Zealand Child and Youth
Epidemiology Service. 483p.
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young people
in the Northern District Health Boards. Commissioned by Northland, Waitemata, Auckland and Counties Manukau DHBs.
Dunedin, New Zealand: New Zealand Child and Youth Epidemiology Service. 561p.
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young people
in the Midland Region. Commissioned by Midland Region DHBs. Dunedin, New Zealand: New Zealand Child and Youth
Epidemiology Service. 564p.
Craig, E., Adams, J., Oben, G., Reddington, A., Wicken, A., & Simpson, J. (2011). The health status of children and young people
in MidCentral and Whanganui. Commissioned by MidCentral and Whanganui DHBs. Dunedin, New Zealand: New
Zealand Child and Youth Epidemiology Service. 499p.
Craig, E., McDonald, G., Adams, J., Reddington, A., Oben, G., & Wicken, A. (2011). The health of children and young people
with chronic conditions and disabilities in New Zealand. Commissioned by Ministry of Health. Dunedin, New Zealand:
New Zealand Child and Youth Epidemiology Service. 261p.
Craig, E., McDonald, G., Adams, J., Reddington, A., Oben, G., & Wicken, A. (2011). The health of Pacific children and young
people with chronic conditions and disabilities in New Zealand. Commissioned by Ministry of Health. Dunedin, New
Zealand: New Zealand Child and Youth Epidemiology Service. 239p.
Craig, E., McDonald, G., Adams, J., Reddington, A., Oben, G., & Wicken, A. (2011). The health of Mäori children and young
people with chronic conditions and disabilities in New Zealand. Commissioned by Ministry of Health. Dunedin, New
Zealand: New Zealand Child and Youth Epidemiology Service. 176p.
University of Otago, Christchurch
Anaesthesia
Journal - Research Article
Chase, J. G., Lambermont, B., Starfinger, C., Hann, C. E., Shaw, G. M., Ghuysen, A., … Desaive, T. (2011). Subject-specific
cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: Animal
experiments and proof of concept. Physiological Measurement, 32(1), 65-82. doi: 10.1088/0967-3334/32/1/005
Davis, M., MacDonald, H., Sames, C., & Nand, K. (2011). Severe cyclophosphamide-induced haemorrhagic cystitis
treated with hyperbaric oxygen. New Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.nz/
journal/124-1340/4816/content.pdf.
Docherty, P. D., Berkeley, J. E., Lotz, T. F., Te Morenga, L., Fisk, L. M., Shaw, G. M., McAuley, K. A., Mann, J. I., Chase, J. G.
(2012). Clinical validation of the quick dynamic insulin sensitivity test. IEEE Transactions on Biomedical Engineering.
Advance online publication. doi: 10.1109/TBME.2012.2232667
Docherty, P. D., Chase, J. G., Te Morenga, L., Lotz, T. F., Berkeley, J. E., Shaw, G. M., McAuley, K. A., Mann, J. I. (2011). A
spectrum of dynamic insulin sensitivity test protocols. Journal of Diabetes Science & Technology, 5(6), 1499-1508.
Drummond, G. B., Bleach, L., Thomson, A. J., & Kennedy, R. R. (2012). Kinetics of anesthetic onset measured with a direct
index of neural activity. Anesthesia & Analgesia, 115(3), 547-553. doi: 10.1213/ANE.0b013e3182549490
Drummond, G. B., Fisher, L., Pumphrey, O., & Kennedy, R. R. (2012). Direct measurement of nitrous oxide kinetics. British
Journal of Anaesthesia, 109(5), 776-781. doi: 10.1093/bja/aes260
Fisk, L. M., Le Compte, A. J., Shaw, G. M., & Chase, J. G. (2012). Improving safety of glucose control in intensive care
using virtual patients and simulated clinical trials. Journal of Healthcare Engineering, 3(3), 415-430. doi: 10.1260/20402295.3.3.415
Hann, C. E., Revie, J., Stevenson, D., Heldmann, S., Desaive, T., Froissart, C. B., … Shaw, G. M., Chase, J. G. (2011). Patient
specific identification of the cardiac driver function in a cardiovascular system model. Computer Methods & Programs in
Biomedicine, 101(2), 201-207. doi: 10.1016/j.cmpb.2010.06.005
Jamaludin, U. K., Docherty, P. D., Chase, J. G., Le Compte, A., Shaw, G. M., Desaive, T., & Preiser, J.-C. (2012). Observation
of incretin effects during enteral feed transitions of critically ill patients. e-SPEN, 7(4), e154-e159. doi: 10.1016/j.
clnme.2012.05.002
Keane, C., Savage, S., McFarlane, K., Seigne, R., Robertson, G., & Eglinton, T. (2012). Enhanced recovery after surgery
versus conventional care in colonic and rectal surgery. ANZ Journal of Surgery, 82(10), 697-703. doi: 10.1111/j.14452197.2012.06139.x
Kennedy, R. R., & French, R. A. (2011). The development of a system to guide volatile anaesthetic administration. Anaesthesia
& Intensive Care, 39(2), 182-190.
Kennedy, R. R., & Merry, A. F. (2011). The effect of a graphical interpretation of a statistic trend indicator (Trigg’s Tracking
Variable) on the detection of simulated changes. Anaesthesia & Intensive Care, 39(5), 881-886.
208
RESEARCH REPORT 2011/2012
Le Compte, A. J., Lynn, A. M., Lin, J., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2012). Pilot study of a model-based approach
to blood glucose control in very-low-birthweight neonates. BMC Pediatrics, 12, 117. doi: 10.1186/1471-2431-12-117
Moran, E. M. L., French, R. A., & Kennedy, R. R. (2011). A New Zealand based cohort study of anaesthetic trainees’ career
outcomes compared with previously expressed intentions. Anaesthesia & Intensive Care, 39(5), 946-950.
Penning, S., Le Compte, A. J., Massion, P., Moorhead, K. T., Pretty, C. G., Preiser, J.-C., Shaw, G. M., … Chase, J. G. (2012).
Second pilot trials of the STAR-Liege protocol for tight glycemic control in critically ill patients. BioMedical Engineering
OnLine, 11, 58. doi: 10.1186/1475-925x-11-58
Penning, S., Le Compte, A. J., Moorhead, K. T., Desaive, T., Massion, P., Preiser, J.-C., Shaw, G. M., Chase, J. G. (2012). First
pilot trial of the STAR-Liege protocol for tight glycemic control in critically ill patients. Computer Methods & Programs in
Biomedicine, 108(2), 844-859. doi: 10.1016/j.cmpb.2011.07.003
Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better
than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391
Pons, T., & Shipton, E. A. (2011). Multilevel lumbar fusion and postoperative physiotherapy rehabilitation in a patient with
persistent pain. Physiotherapy Theory & Practice, 27(3), 238-245. doi: 10.3109/09593985.2010.483268
Pons, T., Shipton, E., & Mulder, R. (2012). The relationship between beliefs about pain and functioning with rheumatologic
conditions. Rehabilitation Research & Practice, 2012, 206263. doi: 10.1155/2012/206263
Shipton, E. A. (2012). Advances in delivery systems and routes for local anaesthetics. Trends in Anaesthesia & Critical Care.
Advance online publication. doi: 10.1016/j.tacc.2012.07.004
Shipton, E. A. (2012). Movement disorders and neuromodulation. Neurology Research International, 2012, 309431. doi:
10.1155/2012/309431
Shipton, E. A. (2011). Pharmacogenomics in acute pain. Trends in Anaesthesia & Critical Care, 1(3), 117-122. doi: 10.1016/j.
tacc.2011.03.001
Shipton, E. A. (2011). The transition from acute to chronic post surgical pain. Anaesthesia & Intensive Care, 39(5), 824-836.
Shipton, E. A. (2011). New formulations of local anaesthetics: Part I. Anesthesiology Research & Practice, 2012, 546409. doi:
10.1155/2012/546409
Shipton, E. A. (2011). New delivery systems for local anaesthetics: Part 2. Anesthesiology Research & Practice, 2012, 289373. doi:
10.1155/2012/289373
Sundaresan, A., Chase, J. G., Hann, C. E., & Shaw, G. M. (2011). Dynamic functional residual capacity can be estimated using a
stress-strain approach. Computer Methods & Programs in Biomedicine, 101(2), 135-143. doi: 10.1016/j.cmpb.2010.05.005
Sundaresan, A., Chase, J. G., Shaw, G. M., Chiew, Y. S., & Desaive, T. (2011). Model-based optimal PEEP in mechanically
ventilated ARDS patients in the Intensive Care Unit. BioMedical Engineering OnLine, 10, 64. doi: 10.1186/1475-925x-10-64
Willis, J. G., Fisk, L., Razak, N., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Insulin Glargine in the intensive care unit:
A model-based clinical trial design. Biomedical Signal Processing & Control. Advance online publication. doi: 10.1016/j.
bspc.2012.09.004
Journal - Research Other
Chase, J. G., & Shaw, G. M. (2012). How standard is the “S” in SMR? [Editorial]. Intensive Care Medicine, 38, 1-3. doi: 10.1007/
s00134-011-2392-0
Foo, E., Williams, D., Singh, H., Bridgman, P. G., McCall, J., & Connor, S. (2012). Successful management of a large air
embolus during an extended right hepatectomy with an emergency cardiopulmonary bypass [Case report]. HPB, 14(12),
871-873. doi: 10.1111/j.1477-2574.2012.00550x
Goucke, R., & Morriss, W. (2012). Pain management in low and middle income countries (LMIC) just put up with it? [Letter].
Egyptian Journal of Anaesthesia, 28(1), 1-2. doi: 10.1016/j.egja.2011.11.005
Spears, C., King, S., Sharples, A., & Beasley, S. (2011). Ranitidine may modify the biochemical disturbance in hypertrophic
pyloric stenosis [Letter to the editor]. ANZ Journal of Surgery, 81(6), 485-486. doi: 10.1111/j.1445-2197.2011.05761.x
van der Griend, B., & Kennedy, R. (2011). Procedural sedation in the emergency department: Good medicine or flirting
with danger? [Editorial]. New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/
journal/124-1344/4901/content.pdf.
University of Otago, Christchurch
Centre for Postgraduate Nursing
Chapter in Book - Research
Whitehead, L. (2011). Qualitative data analysis. In S. Jirojwong, M. Johnson, & A. Welch (Eds.), Research methods in nursing
and midwifery: Pathways to evidence-based practice (pp. 263-284). Melbourne, Australia: Oxford University Press.
Journal - Research Article
Ardagh, M. W., Richardson, S. K., Robinson, V., Than, M., Gee, P., Henderson, S., … McKie, J., Robertson, G., … Deely, J. M.
(2012). The initial health-system response to the earthquake in Christchurch, New Zealand, in February, 2011. Lancet, 379,
2109-2115. doi: 10.1016/s0140-6736(12)60313-4
Burrell, B., & Trip, H. (2011). Reform and community care: Has de-institutionalisation delivered for people with intellectual
disability? Nursing Inquiry, 18(2), 174-183. doi: 10.1111/j.1440-1800.2011.00522.x
209
RESEARCH REPORT 2011/2012
Carlyle, D., Crowe, M., & Deering, D. (2012). Models of care delivery in mental health nursing practice: A mixed method
study. Journal of Psychiatric & Mental Health Nursing, 19(3), 221-230. doi: 10.1111/j.1365-2850.2011.01784.x
Carter, J. D., Crowe, M., Carlyle, D., Frampton, C. M., Jordan, J., McIntosh, V. V. W., O’Toole, V. M., Whitehead, L., Joyce, P. R.
(2012). Patient change processes in psychotherapy: Development of a new scale. Psychotherapy Research, 22(1), 115-126.
doi: 10.1080/10503307.2011.631195
Conder, J., Milner, P., & Mirfin-Veitch, B. (2011). Reflections on a participatory project: The rewards and challenges for the
lead researchers. Journal of Intellectual & Developmental Disability, 36(1), 39-48. doi: 10.3109/13668250.2010.548753
Conder, J., Mirfin-Veitch, B., Sanders, J., & Munford, R. (2011). Planned pregnancy, planned parenting: Enabling choice
for adults with a learning disability. British Journal of Learning Disabilities, 39(2), 105-112. doi: 10.1111/j.14683156.2010.00625.x
Crowe, M., Burrell, B., & Whitehead, L. (2012). Lifestyle risk management: A qualitative analysis of women’s descriptions of
taking hormone therapy following surgically induced menopause. Journal of Advanced Nursing, 68(8), 1814-1823. doi:
10.1111/j.1365-2648.2011.05873.x
Crowe, M., Inder, M., Carlyle, D., Wilson, L., Whitehead, L., Panckhurst, A., … Frampton, C., Joyce, P. (2012). Nurse-led
delivery of specialist supportive care for bipolar disorder: A randomized controlled trial. Journal of Psychiatric & Mental
Health Nursing, 19(5), 446-454. doi: 10.1111/j.1365-2850.2011.01822.x
Crowe, M., Inder, M., Carlyle, D., Wilson, L., Whitehead, L., Panckhurst, A., … Joyce, P. (2012). Feeling out of control: A
qualitative analysis of the impact of bipolar disorder. Journal of Psychiatric & Mental Health Nursing, 19(4), 294-302. doi:
10.1111/j.1365-2850.2011.01786.x
Crowe, M., Whitehead, L., Carlyle, D., McIntosh, V., Jordan, J., Joyce, P., & Carter, J. (2012). The process of change in
psychotherapy for depression: Helping clients to reformulate the problem. Journal of Psychiatric & Mental Health Nursing,
19(8), 681-689. doi: 10.1111/j.1365-2850.2011.01840.x
Dolan, B., Esson, A., Grainger, P., Richardson, S., & Ardagh, M. (2011). Earthquake disaster response in Christchurch, New
Zealand. Journal of Emergency Nursing, 37(5), 506-509. doi: 10.1016/j.jen.2011.06.009
Dunn, J. A., Hay-Smith, E. J. C., Whitehead, L. C., & Keeling, S. (2012). Issues influencing the decision to have upper limb
surgery for people with tetraplegia. Spinal Cord. Advance online publication. doi: 10.1038/sc.2012.58
Dunn, J. A., Hay-Smith, E. J. C., Whitehead, L. C., & Keeling, S. (2012). Liminality and decision making for upper
limb surgery in tetraplegia: A grounded theory. Disability & Rehabilitation. Advance online publication. doi:
10.3109/09638288.2012.727945
Gagan, M. J., & Maybee, P. (2011). Patient satisfaction with nurse practitioner care in primary care settings. Australian Journal
of Advanced Nursing, 28(4), 12-19.
Hale, L. A., Trip, H. T., Whitehead, L., & Conder, J. (2011). Self-management abilities of diabetes in people with an intellectual
disability living in New Zealand. Journal of Policy & Practice in Intellectual Disabilities, 8(4), 223-230. doi: 10.1111/j.17411130.2011.00314.x
Muir, L. A., George, P. M., & Whitehead, L. (2012). Using the experiences of people with familial hypercholesterolaemia to help
reduce the risk of cardiovascular disease: A qualitative systematic review. Journal of Advanced Nursing, 68(9), 1920-1932.
doi: 10.1111/j.1365-2648.2012.05957.x
Mulligan, H. F., Hale, L. A., Whitehead, L., & Baxter, G. D. (2012). Barriers to physical activity for people with long-term
neurological conditions: A review study. Adapted Physical Activity Quarterly, 29(3), 243-265.
Mulligan, H., Whitehead, L. C., Hale, L. A., Baxter, G. D., & Thomas, D. (2012). Promoting physical activity for
individuals with neurological disability: Indications for practice. Disability & Rehabilitation, 34(13), 1108-1113. doi:
10.3109/09638288.2011.631683
Peddie, S., Richardson, S., Salt, L., & Ardagh, M. (2011). Frequent attenders at emergency departments: Research regarding the
utility of management plans fails to take into account the natural attrition of attendance. New Zealand Medical Journal,
124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4581/content.pdf.
Ritchie, L. (2011). Photographs of the ageing body in a nursing journal: A profession’s response. Nursing Inquiry. Advance
online publication. doi: 10.1111/j.1440-1800.2011.00586.x
Tyrrell, E. F., Levack, W. M., Ritchie, L. H., & Keeling, S. M. (2012). Nursing contribution to the rehabilitation of older
patients: Patient and family perspectives. Journal of Advanced Nursing. Advance online publication. doi: 10.1111/j.13652648.2012.05944.x
Whitehead, L. (2011). Methodological issues in internet-mediated research: A randomized comparison of internet versus
mailed questionnaires. Journal of Medical Internet Research, 13(4), e109. doi: 10.2196/jmir.1593
Wilson, L., Whitehead, L., & Burrell, B. (2011). Learning to live well with chronic fatigue: The personal perspective. Journal of
Advanced Nursing, 67(10), 2161-2169. doi: 10.1111/j.1365-2648.2011.05666.x
Working Paper; Discussion Paper; Technical Report
Cook, L., Lord, R., Smith, W., Pasene, M., Belgrave, J., Burgess, K., … Schluter, P., Begg, A. (2012). Mäori Primary Health Care
Report 2010-2011. Christchurch: Combined Canterbury PHOs. 54p.
Cook, L., Pasene, M., Togiaso, G., Smith, W., Lord, R., Burgess, K., … Schluter, P., Begg, A. (2012). Pacific Primary Health Care
Report 2010-2011. Christchurch: Combined Canterbury PHOs. 54p.
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University of Otago, Christchurch
Dean’s Department
Journal - Research Article
Bhandari, S., Chambers, S., Pearson, J., Syhre, M., Epton, M., & Scott-Thomas, A. (2011). Determining the limits and
confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry. Journal of Chromatography B,
879(26), 2815-2820. doi: 10.1016/j.jchromb.2011.08.010
Duthie, J. B., Vincent, M., Herbison, G. P., Wilson, D. I., & Wilson, D. (2011). Botulinum toxin injections for adults with
overactive bladder syndrome (Review). Cochrane Database of Systematic Reviews, 12, CD005493. doi: 10.1002/14651858.
CD005493.pub3
Eglinton, T. W., Roberts, R., Pearson, J., Barclay, M., Merriman, T. R., Frizelle, F. A., & Gearry, R. B. (2012). Clinical and genetic
risk factors for perianal Crohn’s disease in a population-based cohort. American Journal of Gastroenterology, 107, 589-596.
doi: 10.1038/ajg.2011.437
Fernyhough, L. J., Hock, B. D., Taylor, J., Pearson, J., & Ganly, P. (2012). Survival of myeloma patients following the
introduction of thalidomide as a second line therapy: A retrospective study at a single New Zealand centre. Internal
Medicine Journal. Advance online publication. doi: 10.1111/j.1445-5994.2012.02819.x
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., Bentley, R. W. (2011). NOD2
and ATG16L1 polymorphisms affect monocyte responses in Crohn’s disease. World Journal of Gastroenterology, 17(23),
2829-2837. doi: 10.3748/wjg.v17.i23.2829
Heppenstall, C. P., Wilkinson, T. J., Hanger, H. C., Keeling, S., & Pearson, J. (2011). Factors related to care home admission in
the year following hospitalisation in frail older adults. Age & Ageing, 40(4), 513-516. doi: 10.1093/ageing/afr045
Hudson, B., Toop, L., Mangin, D., & Pearson, J. (2011). Risk communication methods in hip fracture prevention: A
randomised trial in primary care. British Journal of General Practice, 61(589), e469-e476. doi: 10.3399/bjgp11X588439
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., …
Dalrymple-Alford, J. C., Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in
Parkinson’s disease. Brain, 134(3), 845-855. doi: 10.1093/brain/awq377
Mitchell, A., Li, R., Brown, J. W., Schönberger, I., & Wen, J. (2012). Ancient divergence and biogeography of Raukaua
(Araliaceae) and close relatives in the southern hemisphere. Australian Systematic Botany, 25(6), 432-446. doi: 10.1071/
SB12020
Pearson, J. F., Fergusson, D. M., Horwood, L. J., Miller, A. L., Sullivan, P. F., Youfang, L. E., & Kennedy, M. A. (2012). Increased
risk of major depression by childhood abuse is not modified by CNR1 genotype. American Journal of Medical Genetics Part
B. Advance online publication. doi: 10.1002/ajmg.b.32124
Pilbrow, A. P., Folkersen, L., Pearson, J. F., Brown, C. M., McNoe, L., Wang, N. M., … Black, M. A., Troughton, R. W., Richards,
A. M., … Cameron, V. A. (2012). The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene
expression in normal heart and vascular tissues. PLoS ONE, 7(6), e39574. doi: 10.1371/journal.pone.0039574
Pitama, S., Ahuriri-Driscoll, A., Huria, T., Lacey, C., & Robertson, P. (2011). The value of te reo in primary care. Journal of
Primary Health Care, 3(2), 123-127.
Pitama, S., Wells, J. E., Faatoese, A., Tikao-Mason, K., Robertson, P., Huria, T., Gillies, T., … Troughton, R., Sheerin, I.,
Richards, M., Cameron, V. A. (2011). A Kaupapa Mäori approach to a community cohort study of heart disease in New
Zealand. Australian & New Zealand Journal of Public Health, 35(3), 249-255. doi: 10.1111/j.1753-6405.2011.00702.x
Prickett, T. C. R., Bothwell, J. C., Yandle, T. G., Richards, A. M., & Espiner, E. A. (2011). Pharmacodynamic responses of plasma
and tissue C-type natriuretic peptide to GH: Correlation with linear growth in GH-deficient rats. Journal of Endocrinology,
15, 217-225. doi: 10.1530/joe-11-0387
Richardson, A. K., Clarke, G., Sabel, C. E., Pearson, J. F., Mason, D. F., & Taylor, B. V. (2012). Method for identifying eligible
individuals for a prevalence survey in the absence of a disease register or population register. Internal Medicine Journal.
Advance online publication. doi: 10.1111/j.1445-5994.2012.02754.x
Rudland, J. R., Schwartz, P., & Ali, A. (2011). Moving a formative test from a paper-based to a computer-based format: A
student viewpoint. Medical Teacher, 33(9), 738-743. doi: 10.3109/0142159X.2011.577119
Scott-Thomas, A., Pearson, J., & Chambers, S. (2011). Potential sources of 2-aminoacetophenone to confound the
Pseudomonas aeruginosa breath test, including analysis of a food challenge study. Journal of Breath Research, 5(4), 046002.
doi: 10.1088/1752-7155/5/4/046002
Wilkinson, T. J., Tweed, M. J., Egan, T. G., Ali, A. N., McKenzie, J. M., Moore, M., & Rudland, J. R. (2011). Joining the dots:
Conditional pass and programmatic assessment enhances recognition of problems with professionalism and factors
hampering student progress. BMC Medical Education, 11, 29. doi: 10.1186/1472-6920-11-29
Journal - Research Other
Pitama, S., Cameron, V., Huria, T., Tikao-Mason, K., Faatoese, A., & Whalley, G. (2011). Adjusting protocols in clinical
research: Finding the point of cultural/clinical fusion. Journal of Primary Health Care, 3(1), 72-73.
Pitama, S., Huria, T., Beckert, L., & Lacey, C. (2011). Assessing the assessment: Cultural competence and understandings
of pain [Editorial]. New Zealand Medical Journal, 124(1328). Retrieved from http://journal.nzma.org.nz/
journal/124-1328/4499/content.pdf.
Wilkinson, T. J. (2011). The medicalisation of medical students [Editorial]. New Zealand Medical Journal, 124(1341). Retrieved
from http://journal.nzma.org.nz/journal/124-1341/4833/content.pdf.
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Wilkinson, T. J., Moore, M., & Flynn, E. M. (2012). Professionalism in its time and place: Some implications for medical
education [Viewpoint]. New Zealand Medical Journal, 125(1358). Retrieved from http://journal.nzma.org.nz/
journal/125-1358/5262/content.pdf.
Commissioned Report for External Body
National Advance Care Planning Cooperative, including Grundy, K., & Moore, M. (2011). Advance care planning: A guide for the
New Zealand health care workforce. Commissioned by Ministry of Health. Wellington, New Zealand: Ministry of Health. 30p.
University of Otago, Christchurch
MAori Indigenous Health Institute
Journal - Research Article
Cameron, V. A., Faatoese, A. F., Gillies, M. W., Robertson, P. J., Huria, T. M., Doughty, R. N., … Richards, M. A., Troughton,
R. W., Tikao-Mason, K. N., Wells, E. J., Sheerin, I. G., Pitama, S. G. (2012). A cohort study comparing cardiovascular risk
factors in rural Mäori, urban Mäori and non-Mäori communities in New Zealand. BMJ Open, 2(3), e000799. doi: 10.1136/
bmjopen-2011-000799
Crowe, M., Porter, R., Inder, M., Lacey, C., Carlyle, D., & Wilson, L. (2012). Effectiveness of interventions to improve
medication adherence in bipolar disorder. Australian & New Zealand Journal of Psychiatry, 46(4), 317-326. doi:
10.1177/0004867411428101
Faatoese, A. F., Pitama, S. G., Gillies, T. W., Robertson, P. J., Huria, T. M., Tikao-Mason, K. N., … Richards, A. M., Troughton,
R. W., Sheerin, I. G., Wells, J. E., Cameron, V. A. (2011). Community screening for cardiovascular risk factors and levels of
treatment in a rural Mäori cohort. Australian & New Zealand Journal of Public Health, 35(6), 517-523. doi: 10.1111/j.17536405.2011.00777.x
Jackson, G., Wright, C., Thornley, S., Taylor, W. J., Te Karu, L., Gow, P. J., … Winnard, D. (2012). Potential unmet need for gout
diagnosis and treatment: Capture-recapture analysis of a national administrative dataset. Rheumatology. Advance online
publication. doi: 10.1093/rheumatology/kes147
Pitama, S., Cave, T., Huria, T., Lacey, C., Cuddy, J., & Frizelle, F. (2012). Exploring Mäori health worker perspectives
on colorectal screening. New Zealand Medical Journal, 125(1356). Retrieved from http://journal.nzma.org.nz/
journal/125-1356/5214/content.pdf.
Winnard, D., Wright, C., Taylor, W. J., Jackson, G., Te Karu, L., Gow, P. J., … Dalbeth, N. (2012). National prevalence of
gout derived from administrative health data in Aotearoa New Zealand. Rheumatology, 51(5), 901-909. doi: 10.1093/
rheumatology/ker361
Journal - Research Other
Lacey, C. (2012). Re: Sanders et al. (2011) Differences in patients’ perceptions of Schizophrenia between Maori and
New Zealand Europeans [Letter to the editor]. Australian & New Zealand Journal of Psychiatry, 46(3), 279. doi:
10.1177/0004867411432077
Lacey, C., Huria, T., Beckert, L., Gillies, M., & Pitama, S. (2011). The Hui Process: A framework to enhance the doctor–patient
relationship with Mäori [Viewpoint]. New Zealand Medical Journal, 124(1347). Retrieved from http://journal.nzma.org.
nz/journal/124-1347/5003/content.pdf.
Sheerin, I., Pitama, S., Wells, J. E., Faatoese, A., Richards, M., Troughton, R., Tikao-Mason, K., Huria, T., Robertson, P., Gillies,
M., … Cameron, V. (2012). Loose tobacco, ethnicity, income and rurality [Letter]. Australian & New Zealand Journal of
Public Health, 36(3), 291-292. doi: 10.1111/j.1753-6405.2012.00873.x
Journal - Professional & Other Non-Research Articles
Lacey, C. (2011). [Review of book Teaching psychiatry to undergraduates]. New Zealand Medical Journal, 124(1341). Retrieved
from http://journal.nzma.org.nz/journal/124-1341/4849/content.pdf.
University of Otago, Christchurch
Medicine
Chapter in Book - Research
Dalbeth, N., & Stamp, L. K. (2011). Xanthine oxidase inhibitor treatment of hyperuricemia. In R. Terkeltaub (Ed.), Gout and
other crystal arthropathies (pp. 154-173). Philadelphia, PA: Saunders. doi: 10.1016/B978-1-4377-2864-4.10039-9
Pickering, J. W., & Endre, Z. H. (2012). The metamorphosis of acute renal failure to acute kidney injury. In M. Sahay (Ed.),
Basic nephrology and acute kidney injury (pp. 125-150). Rijeka, Croatia: InTech. doi: 10.5772/1298
Prickett, T. C. R., & Espiner, E. A. (2011). C-type natriuretic peptide (CNP) and postnatal linear growth. In V. R. Preedy (Ed.),
Handbook of growth and growth monitoring in health and disease (pp. 2789-2809). New York: Springer. doi: 10.1007/978-14419-1795-9
Richards, A. M., Troughton, R. W., & Nicholls, M. G. (2011). Natriuretic peptides for guidance of acute and chronic heart failure
therapy. In J. L. Januzzi, Jr. (Ed.), Cardiac biomarkers in clinical practice (pp. 559-580). Sudbury, MA: Jones & Bartlett.
Teunissen, P. W., & Wilkinson, T. J. (2011). Learning and teaching in workplaces. In T. Dornan, K. Mann, A. Scherpbier, & J.
Spencer (Eds.), Medical education: Theory and practice (pp. 193-210). Edinburgh: Churchill Livingstone.
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Collaborative Depression and Sexual Dysfunction (CDS) in Hemodialysis Working Group, including Palmer, S. (2012).
Prevalence and correlates of erectile dysfunction in men on chronic haemodialysis: A multinational cross-sectional study.
Nephrology Dialysis Transplantation, 27(6), 2479-2488. doi: 10.1093/ndt/gfr635
Alamri, Y. A. (2011). Rains and floods in Saudi Arabia: Crying of the sky or of the people?. Saudi Medical Journal, 32(3), 311-313.
Aldous, S. J., Florkowski, C. M., Crozier, I. G., Elliott, J., George, P., Lainchbury, J. G., MacKay, R. J., Than, M. (2011).
Comparison of high sensitivity and contemporary troponin assays for the early detection of acute myocardial infarction in
the emergency department. Annals of Clinical Biochemistry, 48, 241-248. doi: 10.1258/acb.2010.010219
Aldous, S., Pemberton, C., Richards, A. M., Troughton, R., & Than, M. (2012). High-sensitivity troponin T for early ruleout of myocardial infarction in recent onset chest pain. Emergency Medicine Journal, 29(10), 805-810. doi: 10.1136/
emermed-2011-200222
Aldous, S., Smyth, D., Blake, J., McClean, D., & Elliott, J. (2011). The real world experience of the everolimus-eluting coronary
stent system: Audit of everolimus-eluting coronary stents. Journal of Interventional Cardiology, 24(3), 241-246. doi:
10.1111/j.1540-8183.2011.00633.x
Ali, M. A., Adem, A., Chandranath, I. S., Benedict, S., Pathan, J. Y., Nagelkerke, N., … Lewis, L. K., Yandle, T. G., Nicholls, G.
M., Frampton, C. M., Kazzam, E. (2012). Responses to dehydration in the one-humped camel and effects of blocking the
renin-angiotensin system. PLoS ONE, 7(5), e37299. doi: 10.1371/journal.pone.0037299
Aliprandi-Costa, B., Ranasinghe, I., Chow, V., Kapila, S., Juergens, C., Devlin, G., Elliott, J., … Brieger, D. B. (2011).
Management and outcomes of patients with acute coronary syndromes in Australia and New Zealand, 2000–2007. Medical
Journal of Australia, 195(3), 116-121.
Allardyce, R. A., Bagshaw, P. F., Frampton, C. M., Frizelle, F. A., Hewett, P. J., Rieger, N. A., … Stevenson, A. R. L. (2011). Ethical
issues with the disclosure of surgical trial short-term data. ANZ Journal of Surgery, 81(3), 125-131. doi: 10.1111/j.14452197.2010.05433.x
Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’Amato, M., Taylor, K. D., … Barclay, M., … Roberts, R., … Gearry,
R., … Rioux, J. D. (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of
confirmed associations to 47. Nature Genetics, 43(3), 246-254. doi: 10.1038/ng.764
Ardagh, M. W., Richardson, S. K., Robinson, V., Than, M., Gee, P., Henderson, S., … McKie, J., Robertson, G., … Deely, J. M.
(2012). The initial health-system response to the earthquake in Christchurch, New Zealand, in February, 2011. Lancet, 379,
2109-2115. doi: 10.1016/s0140-6736(12)60313-4
Bacht, T., Chase, J. G., MacRae, G., Rodgers, G. W., Rabczuk, T., Dhakal, R. P., & Desombre, J. (2011). HF2V dissipator effects
on the performance of a 3 story moment frame. Journal of Constructional Steel Research, 67(12), 1843-1849. doi: 10.1016/j.
jcsr.2011.05.007
Bagshaw, P. F., Allardyce, R. A., Frampton, C. M., Frizelle, F. A., Hewett, P. J., McMurrick, P. J., … and the Australasian
Laparoscopic Colon Cancer Study Group. (2012). Long-term outcomes of the Australasian randomized clinical trial
comparing laparoscopic and conventional open surgical treatments for colon cancer: The Australasian Laparoscopic
Colon Cancer Study trial. Annals of Surgery, 256(6), 915-919. doi: 10.1097/SLA.0b013e3182765ff8
Begg, E. J., Helsby, N. A., & Jensen, B. P. (2012). Pharmacogenetics of drug-metabolizing enzymes: The prodrug hypothesis.
Pharmacogenomics, 13(1), 83-89. doi: 10.2217/pgs.11.134
Bell, C., Bhikha, S., Colhoun, H., Carter, F., Frampton, C., & Porter, R. (2012). The response to sulpiride in social
anxiety disorder: D2 receptor function. Journal of Psychopharmacology. Advance online publication. doi:
10.1177/0269881112450778
Bell, C., Bourke, C., Colhoun, H., Carter, F., Frampton, C., & Porter, R. (2011). The misclassification of facial expressions in
generalised social phobia. Journal of Anxiety Disorders, 25(2), 278-283. doi: 10.1016/j.janxdis.2010.10.001
Bell, C. J., Colhoun, H. C., Carter, F. A., & Frampton, C. M. (2012). Effectiveness of computerised cognitive behaviour
therapy for anxiety disorders in secondary care. Australian & New Zealand Journal of Psychiatry, 46(7), 630-640. doi:
10.1177/0004867412437345
Bell, C., Hood, S., Potokar, J., Nash, J., Adrover, M., Frampton, C., … Nutt, D. (2011). Rapid tryptophan depletion following
cognitive behavioural therapy for panic disorder. Psychopharmacology, 213(2-3), 593-602. doi: 10.1007/s00213-009-1696-z
Bentley, R. W., Keown, D. A., Gearry, R. B., Cameron, V. A., Keenan, J., Roberts, R. L., & Day, A. S. (2012). Vitamin D receptor
polymorphisms in colorectal cancer in New Zealand: An association study. New Zealand Medical Journal, 125(1356).
Retrieved from http://journal.nzma.org.nz/journal/125-1356/5212/content.pdf.
Bhandari, S., Chambers, S., Pearson, J., Syhre, M., Epton, M., & Scott-Thomas, A. (2011). Determining the limits and
confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry. Journal of Chromatography B,
879(26), 2815-2820. doi: 10.1016/j.jchromb.2011.08.010
Bird, P. A., Murray, D. P., Zhang, M., & Begg, E. J. (2011). Intratympanic versus intravenous delivery of dexamethasone
and dexamethasone sodium phosphate to cochlear perilymph. Otology & Neurotology, 32(6), 933-936. doi: 10.1097/
MAO.0b013e3182255933
Bolland, M. J., Holdaway, I. M., Berkeley, J. E., Lim, S., Dransfield, W. J., Conaglen, J. V., … Hunt, P. J., Toomath, R. J.
(2011). Mortality and morbidity in Cushing’s syndrome in New Zealand. Clinical Endocrinology, 75(4), 436-442. doi:
10.1111/j.1365-2265.2011.04124.x
Borrie, S. A., McAuliffe, M. J., Liss, J. M., Kirk, C., O’Beirne, G. A., & Anderson, T. (2012). Familiarisation conditions and the
mechanisms that underlie improved recognition of dysarthric speech. Language & Cognitive Processes, 27(7-8), 1039-1055.
doi: 10.1080/01690965.2011.610596
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Boyle, M. J., Frampton, C. M. A., & Crawford, H. A. (2012). Early results of total hip arthroplasty in patients with
developmental dysplasia of the hip compared with patients with osteoarthritis. Journal of Arthroplasty, 27(3), 386-390. doi:
10.1016/j.arth.2011.06.024
Boyle, M. J., Singleton, N., Frampton, C. M. A., & Muir, D. (2012). Functional response to total hip arthroplasty in patients
with hip dysplasia. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/j.1445-2197.2012.06198.x
Boyle, M. J., Youn, S.-M., Frampton, C. M. A., & Ball, C. M. (2012). Functional outcomes of reverse shoulder arthroplasty
compared with hemiarthroplasty for acute proximal humeral fractures. Journal of Shoulder & Elbow Surgery, (0). Advance
online publication. doi: 10.1016/j.jse.2012.03.006
Braatvedt, G. D., Cundy, T., Crooke, M., Florkowski, C., Mann, J. I., Lunt, H., … Drury, P. L. (2012). Understanding the new
HbA1c units for the diagnosis of Type 2 diabetes [Review article]. New Zealand Medical Journal, 125(1362). Retrieved
from http://journal.nzma.org.nz/journal/125-1362/5345/content.pdf.
Braithwaite, J. E., Yandle, T. G., Nicholls, M. G., & Lewis, L. K. (2012). Interference by o-phenanthroline in the
radioimmunoassay of angiotensin II in small volume blood samples. Clinical Biochemistry, 45(1-2), 168-170. doi:
10.1016/j.clinbiochem.2011.10.008
Burgess, S. N., Harding, S. A., Melton, I. C., Lever, N. A., Swain, A. H., Shi, B., & Larsen, P. D. (2011). An unmet need for
implantable cardioverter-defibrillators in New Zealand. Europace, 13(9), 1299-1303. doi: 10.1093/europace/eur113
Butler, A. P. H., Butzer, J., Schleich, N., Cook, N. J., Anderson, N. G., Scott, N., de Ruiter, N., … Butler, P. H. (2011). Processing
of spectral X-ray data with principal components analysis. Nuclear Instruments & Methods in Physics Research Section A,
633(Suppl. 1), S140-S142. doi: 10.1016/j.nima.2010.06.149
Byrne, S., & Mason, D. (2012). A review of interferon use in patients with relapsing remitting multiple sclerosis in the
Canterbury region, New Zealand: 2000–2006. New Zealand Medical Journal, 125(1350). Retrieved from http://journal.
nzma.org.nz/journal/125-1350/5082/content.pdf.
Byun, S. O., Forrest, R. H., Frampton, C. M., Zhou, H., & Hickford, J. G. H. (2012). An association between lifespan and
variation in insulin-like growth factor I receptor in sheep. Journal of Animal Science, 90(8), 2484-2487. doi: 10.2527/
jas2011-4148
Callahan, A., Amarenco, P., Goldstein, L. B., Sillesen, H., Messig, M., Samsa, G. P., … Scott, R., … for the SPARCL Investigators.
(2011). Risk of stroke and cardiovascular events after ischemic stroke or transient ischemic attack in patients with type
2 diabetes or metabolic syndrome: Secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol
Levels (SPARCL) Trial. Archives of Neurology, 68(10), 1245-1251. doi: 10.1001/archneurol.2011.146
Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R., Silvers, K. M., Epton, M. J., Town, G. I., Pattemore, P. K., … Crane, J.,
the New Zealand Asthma and Allergy Cohort Study Group (NZAAACS6). (2011). Cord-blood 25-hydroxyvitamin D levels
and risk of respiratory infection, wheezing, and asthma. Pediatrics, 127(1), e180-e187. doi: 10.1542/peds.2010-0442
Cameron, V. A., Faatoese, A. F., Gillies, M. W., Robertson, P. J., Huria, T. M., Doughty, R. N., … Richards, M. A., Troughton,
R. W., Tikao-Mason, K. N., Wells, E. J., Sheerin, I. G., Pitama, S. G. (2012). A cohort study comparing cardiovascular risk
factors in rural Mäori, urban Mäori and non-Mäori communities in New Zealand. BMJ Open, 2(3), e000799. doi: 10.1136/
bmjopen-2011-000799
Carter, J. D., Luty, S. E., McKenzie, J. M., Mulder, R. T., Frampton, C. M., & Joyce, P. R. (2011). Patient predictors of response
to cognitive behaviour therapy and interpersonal psychotherapy in a randomised clinical trial for depression. Journal of
Affective Disorders, 128, 252-261. doi: 10.1016/j.jad.2010.07.002
Chambers, S. T., Scott-Thomas, A., & Epton, M. (2012). Developments in novel breath tests for bacterial and fungal
pulmonary infection. Current Opinion in Pulmonary Medicine, 18(3), 228-232. doi: 10.1097/MCP.0b013e328351f98b
Charles, C. J. (2011). Update on apelin peptides as putative targets for cardiovascular drug discovery. Expert Opinion on Drug
Discovery, 6(6), 633-644. doi: 10.1517/17460441.2011.571251
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, M. (2011). Urocortin 3 inhibits cardiac sympathetic nerve activity
in conscious sheep. Journal of Cardiovascular Pharmacology, 58(4), 418-423. doi: 10.1097/FJC.0b013e31822707a4
Charles, C. J., Rademaker, M. T., & Richards, A. M. (2011). Hemodynamic, hormonal, and renal actions of adrenomedullin-5
in normal conscious sheep. Journal of Cardiovascular Pharmacology, 58(1), 25-31. doi: 10.1097/FJC.0b013e31821a9473
Chase, J. G., Lambermont, B., Starfinger, C., Hann, C. E., Shaw, G. M., Ghuysen, A., … Desaive, T. (2011). Subject-specific
cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: Animal
experiments and proof of concept. Physiological Measurement, 32(1), 65-82. doi: 10.1088/0967-3334/32/1/005
Chase, J. G., Le Compte, A. J., Suhaimi, F., Shaw, G. M., Lynn, A., Lin, J., … Desaive, T. (2011). Tight glycemic control in critical
care: The leading role of insulin sensitivity and patient variability: A review and model-based analysis. Computer Methods
& Programs in Biomedicine, 102(2), 156-171. doi: 10.1016/j.cmpb.2010.11.006
Chen-Xu, M., Topless, R., McKinney, C., Merriman, M. E., Phipps-Green, A., Dalbeth, N., … Harrison, A. A., Highton, J., …
van Rij, A., Jones, G. T., … Stamp, L. K., … Merriman, T. R. (2012). Replication of association of the interleukin 23
receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets. Annals of the Rheumatic Diseases, 71(1),
155-157. doi: 10.1136/annrheumdis-2011-200591
Chew-Harris, J. S. C., Florkowski, C. M., George, P. M., Elmslie, J. L., & Endre, Z. H. (2012). The relative effects of fat versus
muscle mass on cystatin C and estimates of renal function in healthy young men. Annals of Clinical Biochemistry. Advance
online publication. doi: 10.1258/acb.2012.011241
Child, N., Barber, P. A., Fink, J., Jones, S., Voges, K., & Vivian, M. (2011). New Zealand National Acute Stroke Services Audit
2009: Organisation of acute stroke services in New Zealand. New Zealand Medical Journal, 124(1340). Retrieved from
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Child, N., Fink, J., Jones, S., Voges, K., Vivian, M., & Barber, P. A. (2012). New Zealand National Acute Stroke Services Audit:
Acute stroke care delivery in New Zealand. New Zealand Medical Journal, 125(1358). Retrieved from http://journal.nzma.
org.nz/journal/125-1358/5268/content.pdf.
Chin, P. K. L., Jensen, B. P., Larsen, H. S., & Begg, E. J. (2011). Adult age and ex vivo protein binding of lorazepam, oxazepam
and temazepam in healthy subjects. British Journal of Clinical Pharmacology, 72(6), 985-989. doi: 10.1111/j.13652125.2011.04036.x
Collins, C., Copeland, B., & Croucher, M. (2011). Bipolar affective disorder, type II, apparently precipitated by donepezil.
International Psychogeriatrics, 23(3), 503-504. doi: 10.1017/s1041610210002206
Coolbear, F., & Crozier, I. (2011). Surgical radiofrequency ablation for atrial fibrillation: The Christchurch, New Zealand
experience. New Zealand Medical Journal, 124(1343). Retrieved from http://journal.nzma.org.nz/journal/124-1343/4877/
content.pdf.
Crane, J., Lampshire, P., Wickens, K., Epton, M., Siebers, R., Ingham, T., Pattemore, P., Town, I., and the Year Six New Zealand
Asthma and Allergy Cohort Study Group, (NZAACS6). (2012). Asthma, atopy and exhaled nitric oxide in a cohort of 6-yrold New Zealand children. Pediatric Allergy & Immunology, 23(1), 59-64. doi: 10.1111/j.1399-3038.2011.01227.x
Currie, M. J., Beardsley, B. E., Harris, G. C., Gunningham, S. P., Dachs, G. U., Dijkstra, B., Morrin, H. R., Wells, J. E., Robinson,
B. A. (2012). Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal
carcinoma in situ: Relationships with markers of tumor hypoxia and microvascularity. Human Pathology. Advance online
publication. doi: 10.1016/j.humpath.2012.06.004
Dalbeth, N., McQueen, F. M., Singh, J. A., MacDonald, P. A., Edwards, N. L., Schumacher, Jr, H. R., … Stamp, L. K., … Taylor,
W. J. (2011). Tophus measurement as an outcome measure for clinical trials of chronic gout: Progress and research
priorities. Journal of Rheumatology, 38(7), 1458-1461. doi: 10.3899/jrheum.110272
Dalrymple-Alford, J. C., Livingston, L., MacAskill, M. R., Graham, C., Melzer, T. R., Porter, R. J., … Anderson, T. J. (2011).
Characterizing mild cognitive impairment in Parkinson’s disease. Movement Disorders, 26(4), 629-636. doi: 10.1002/
mds.23592
Daly, M., Melton, I., & Crozier, I. (2011). Pulmonary vein ablation for atrial fibrillation: The Christchurch, New Zealand
experience. New Zealand Medical Journal, 124(1343). Retrieved from http://journal.nzma.org.nz/journal/124-1343/4878/
content.pdf.
Daniels, L. B., Clopton, P., Potocki, M., Mueller, C., McCord, J., Richards, M., … Maisel, A. S. (2012). Influence of age, race,
sex, and body mass index on interpretation of midregional pro atrial natriuretic peptide for the diagnosis of acute heart
failure: Results from the BACH multinational study. European Journal of Heart Failure, 14(1), 22-31. doi: 10.1093/eurjhf/
hfr157
Davey, V., Robinson, B., Dijkstra, B., & Harris, G. (2012). The Christchurch Breast Cancer Patient Register: The first year. New
Zealand Medical Journal, 125(1360). Retrieved from http://journal.nzma.org.nz/journal/125-1360/5301/content.pdf.
Denic, S., & Nicholls, M. G. (2011). A call for screening for benign neutropenia in Arab populations. Saudi Medical Journal,
32(7), 738-739.
Desombre, J., Rodgers, G. W., MacRae, G. A., Rabczuk, T., Dhakal, R. P., & Chase, J. G. (2011). Experimentally validated FEA
models of HF2V damage free steel connections for use in full structural analyses. Structural Engineering & Mechanics,
37(4).
Diaz-Gallo, L.-M., Espino-Paisán, L., Fransen, K., Gómez-García, M., van Sommeren, S., Cardeña, C., … Barclay, M. L., …
Gearry, R. B., Roberts, R. L., … Merriman, T. R., … Martin, J. (2011). Differential association of two PTPN22 coding
variants with Crohn’s disease and ulcerative colitis. Inflammatory Bowel Diseases, 17(11), 2287-2294. doi: 10.1002/
ibd.21630
Docherty, P. D., Berkeley, J. E., Lotz, T. F., Te Morenga, L., Fisk, L. M., Shaw, G. M., McAuley, K. A., Mann, J. I., Chase, J. G.
(2012). Clinical validation of the quick dynamic insulin sensitivity test. IEEE Transactions on Biomedical Engineering.
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Docherty, P. D., Chase, J. G., Lotz, T. F., Hann, C. E., Shaw, G. M., Berkeley, J. E., TeMorenga, L., Mann, J. I., McAuley, K.
(2011). Independent cohort cross-validation of the real-time DISTq estimation of insulin sensitivity. Computer Methods &
Programs in Biomedicine, 102(2), 94-104. doi: 10.1016/j.cmpb.2010.08.002
Docherty, P. D., Chase, J. G., Te Morenga, L., Lotz, T. F., Berkeley, J. E., Shaw, G. M., McAuley, K. A., Mann, J. I. (2011). A
spectrum of dynamic insulin sensitivity test protocols. Journal of Diabetes Science & Technology, 5(6), 1499-1508.
Dummer, J., Storer, M., Swanney, M., McEwan, M., Scott-Thomas, A., Bhandari, S., Chambers, S., … Epton, M. (2011).
Analysis of biogenic volatile organic compounds in human health and disease. Trends in Analytical Chemistry, 30(7), 960967. doi: 10.1016/j.trac.2011.03.011
Dunn, J. A., Hay-Smith, E. J. C., Whitehead, L. C., & Keeling, S. (2012). Issues influencing the decision to have upper limb
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Dyall, L., Kerse, N., Hayman, K., & Keeling, S. (2011). Pinnacle of life: Mäori living to advanced age [Viewpoint]. New Zealand
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Eady, S., Wallace, A., Willis, J., Scott, R., & Frampton, C. (2011). Consumption of a plant sterol-based spread derived from rice
bran oil is effective at reducing plasma lipid levels in mildly hypercholesterolaemic individuals. British Journal of Nutrition,
105(12), 1808-1818. doi: 10.1017/S0007114510005519
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Eggleston, M., Hanger, N., Frampton, C., & Watkins, W. (2012). Coordination difficulties and self-esteem: A review and
findings from a New Zealand survey. Australian Occupational Therapy Journal, 59(6), 456-462. doi: 10.1111/14401630.12007
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risk factors for perianal Crohn’s disease in a population-based cohort. American Journal of Gastroenterology, 107, 589-596.
doi: 10.1038/ajg.2011.437
Ellis, E., Chin, P. K. L., Hunt, P. J., Lunt, H., Lewis, J. G., & Soule, S. G. (2012). Is late-night salivary cortisol a better screening
test for possible cortisol excess than standard screening tests in obese patients with Type 2 diabetes? New Zealand Medical
Journal, 125(1353). Retrieved from http://journal.nzma.org.nz/journal/125-1353/5151/content.pdf.
Ellis, K. L., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Skelton, L., Thomson, J. A.,
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with subsequent cardiovascular outcomes in healthy controls and in established coronary artery disease. Circulation:
Cardiovascular Genetics, 4(6), 636-646. doi: 10.1161/circgenetics.111.960336
Ellis, K. L., Newton-Cheh, C., Wang, T. J., Frampton, C. M., Doughty, R. N., Whalley, G. A., … Skelton, L., Davis, N., Yandle,
T. G., Troughton, R. W., Richards, A. M., Cameron, V. A. (2011). Association of genetic variation in the natriuretic
peptide system with cardiovascular outcomes. Journal of Molecular & Cellular Cardiology, 50(4), 695-701. doi: 10.1016/j.
yjmcc.2011.01.010
Ellis, K. L., Palmer, B. R., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Pilbrow, A. P., Skelton, L.,
Yandle, T. G., Richards, A. M., Cameron, V. A. (2012). Genetic variation in the renin-angiotensin-aldosterone system is
associated with cardiovascular risk factors and early mortality in established coronary heart disease. Journal of Human
Hypertension. Advance online publication. doi: 10.1038/jhh.2012.24
Endre, Z. H., & Pickering, J. W. (2012). Acute kidney injury clinical trial design: Old problems, new strategies. Pediatric
Nephrology. Advance online publication. doi: 10.1007/s00467-012-2171-3
Endre, Z. H., & Pickering, J. W. (2011). New markers of acute kidney injury: Giant leaps and baby steps. Clinical Biochemist
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Endre, Z. H., Pickering, J. W., & Walker, R. J. (2011). Clearance and beyond: The complementary roles of GFR measurement
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Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M.,
Henderson, S. J., Nejat, M., Schollum, J. B. W., George, P. M. (2011). Improved performance of urinary biomarkers of acute
kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79,
1119-1130. doi: 10.1038/ki.2010.555
Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin
interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic
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Evans, G. E., Phillipson, G. T. M., Sin, I. L., Frampton, C. M. A., Kirker, J. A., Bigby, S. M., & Evans, J. J. (2012). Gene expression
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Faatoese, A. F., Pitama, S. G., Gillies, T. W., Robertson, P. J., Huria, T. M., Tikao-Mason, K. N., … Richards, A. M., Troughton,
R. W., Sheerin, I. G., Wells, J. E., Cameron, V. A. (2011). Community screening for cardiovascular risk factors and levels of
treatment in a rural Mäori cohort. Australian & New Zealand Journal of Public Health, 35(6), 517-523. doi: 10.1111/j.17536405.2011.00777.x
Felker, G. M., Hasselblad, V., Tang, W. H. W., Hernandez, A. F., Armstrong, P. W., Fonarow, G. C., … Troughton, R. W., …
O’Connor, C. M. (2012). Troponin I in acute decompensated heart failure: Insights from the ASCEND-HF study. European
Journal of Heart Failure, 14(11), 1257-1264. doi: 10.1093/eurjhf/hfs110
Fernando, K., Carter, J. D., Frampton, C. M. A., Luty, S. E., McKenzie, J., Mulder, R. T., & Joyce, P. R. (2011). Childhood-,
teenage-, and adult-onset depression: Diagnostic and individual characteristics in a clinical sample. Comprehensive
Psychiatry, 52, 623-629. doi: 10.1016/j.comppsych.2010.12.006
Fernyhough, L. J., Hock, B. D., Taylor, J., Pearson, J., & Ganly, P. (2012). Survival of myeloma patients following the
introduction of thalidomide as a second line therapy: A retrospective study at a single New Zealand centre. Internal
Medicine Journal. Advance online publication. doi: 10.1111/j.1445-5994.2012.02819.x
Fleming, T., Dixon, R., Frampton, C., & Merry, S. (2012). A pragmatic randomized controlled trial of computerized CBT
(SPARX) for symptoms of depression among adolescents excluded from mainstream education. Behavioural & Cognitive
Psychotherapy, 40(5), 529-541. doi: 10.1017/s1352465811000695
Frevel, M. A. E., Pipingas, A., Grigsby, W. J., Frampton, C. M., & Gilchrist, N. L. (2012). Production, composition and
toxicology studies of Enzogenol® Pinus radiata bark extract. Food & Chemical Toxicology. Advance online publication. doi:
10.1016/j.fct.2012.08.051
Fukuda, K., Hider, P. N., Epton, M. J., Jennings, L. C., & Kingham, S. (2011). Including viral infection data supports an
association between particulate pollution and respiratory admissions. Australian & New Zealand Journal of Public Health,
35(2), 163-169. doi: 10.1111/j.1753-6405.2010.00620.x
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Gaggin, H. K., Truong, Q. A., Rehman, S. U., Mohammed, A. A., Bhardwaj, A., Parks, K. A., … Richards, A. M., Troughton, R.
W., Lainchbury, J. G., … Januzzi, J. L. (2012). Characterization and prediction of natriuretic peptide “nonresponse” during
heart failure management: Results from the ProBNP outpatient tailored chronic heart failure (PROTECT) and the NTproBNP–assisted treatment to lessen serial cardiac readmissions and death (BATTLESCARRED) study. Congestive Heart
Failure. Advance online publication. doi: 10.1111/chf.12016
Gane, E. J., Rouzier, R., Stedman, C., Wiercinska-Drapalo, A., Horban, A., Chang, L., … Tran, J. Q. (2011). Antiviral activity,
safety, and pharmacokinetics of danoprevir/ritonavir plus PEG-IFN α-2a/RBV in hepatitis C patients. Journal of
Hepatology, 55, 972-979.
Gardiner, S. J., Gearry, R. B., Burt, M. J., Chalmers-Watson, T., Chapman, B. A., Ross, A. G., Stedman, C. A. M., … Barclay,
M. L. (2011). Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable
metabolite ratio. Journal of Gastroenterology & Hepatology, 26(1), 49-54. doi: 10.1111/j.1440-1746.2010.06489.x
Gauld, N. J., Jennings, L. C., Frampton, C., & Huang, Q. S. (2012). Five years of non-prescription oseltamivir: Effects on
resistance, immunization and stockpiling. Journal of Antimicrobial Chemotherapy, 67(12), 2949-2956. doi: 10.1093/jac/dks337
International Multiple Sclerosis Genetics Consortium, and the Wellcome Trust Case Control Consortium 2, including Mason,
D., & Mottershead, J. (2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature, 476, 214-219. doi: 10.1038/nature10251
Gilchrist, N., Hooper, G., Frampton, C., Maguire, P., Heard, A., March, R. L., Maxwell, R., Penny, I. (2012). Measurement of
bone density around the Oxford medial compartment knee replacement using iDXA: A precision study. Journal of Clinical
Densitometry. Advance online publication. doi: 10.1016/j.jocd.2012.02.015
Gilling, P. J., Wilson, L. C., King, C. J., Westenberg, A. M., Frampton, C. M., & Fraundorfer, M. R. (2012). Long-term results
of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate:
Results at 7 years. BJU International, 109(3), 408-411. doi: 10.1111/j.1464-410X.2011.10359.x
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., Bentley, R. W. (2011). NOD2
and ATG16L1 polymorphisms affect monocyte responses in Crohn’s disease. World Journal of Gastroenterology, 17(23),
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Greenslade, J. H., Cullen, L., Parsonage, W., Reid, C. M., Body, R., Richards, M., … Than, M. (2012). Examining the signs and
symptoms experienced by individuals with suspected acute coronary syndrome in the Asia-Pacific Region: A prospective
observational study. Annals of Emergency Medicine. Advance online publication. doi: 10.1016/j.annemergmed.2012.05.008
Haines, M. L., Ajlouni, Y., Irving, P. M., Sparrow, M. P., Rose, R., Gearry, R. B., & Gibson, P. R. (2011). Clinical usefulness
of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease.
Inflammatory Bowel Diseases, 17(6), 1301-1307. doi: 10.1002/ibd.21458
Hamid, A. K., Richards, A. M., Crozier, I. G., Lainchbury, J. G., Melton, I., Bridgman, P. G., Palmer, S. C., Frampton, C. M.,
Nicholls, M. G. (2011). Prediction of cardiac rhythm 1 year following cardioversion for atrial fibrillation. New Zealand
Medical Journal, 124(1343). Retrieved from http://journal.nzma.org.nz/journal/124-1343/4881/content.pdf.
Hanger, H. C., Fletcher, V., & Sidwell, A. (2011). Acute medical admissions of older people from residential care facilities:
Are they appropriate? New Zealand Medical Journal, 124(1337). Retrieved from http://journal.nzma.org.nz/
journal/124-1337/4731/content.pdf.
Hann, C. E., Revie, J., Stevenson, D., Heldmann, S., Desaive, T., Froissart, C. B., … Shaw, G. M., Chase, J. G. (2011). Patient
specific identification of the cardiac driver function in a cardiovascular system model. Computer Methods & Programs in
Biomedicine, 101(2), 201-207. doi: 10.1016/j.cmpb.2010.06.005
Hazlett, J., Stamp, L. K., Merriman, T., Highton, J., & Hessian, P. A. (2011). IL-23R rs11209026 polymorphism modulates IL17A expression in patients with rheumatoid arthritis. Genes & Immunity. doi: 10.1038/gene.2011.80
Heard, A., March, R., Maguire, P., Reilly, P., Helmore, J., Cameron, S., Frampton, C., Nicholls, G., Gilchrist, N. (2012).
Recruitment strategies for an osteoporosis clinical trial: Analysis of effectiveness. Australasian Journal on Ageing, 31(3),
176-180. doi: 10.1111/j.1741-6612.2011.00573.x
Heppenstall, C. P., Keeling, S., Hanger, H. C., & Wilkinson, T. J. (2012). Perceived factors which shape decision-making around
the time of residential care admission in older adults: A qualitative study. Australasian Journal on Ageing. Advance online
publication. doi: 10.1111/j.1741-6612.2012.00644.x
Heppenstall, C. P., Wilkinson, T. J., Hanger, H. C., Keeling, S., & Pearson, J. (2011). Factors related to care home admission in
the year following hospitalisation in frail older adults. Age & Ageing, 40(4), 513-516. doi: 10.1093/ageing/afr045
Hickford, J. G. H., Forrest, R. H. J., Zhou, H., Fang, Q., & Frampton, C. M. (2011). Association between variation in faecal egg
count for a mixed field-challenge of nematode parasites and ovine MHC-DQA2 polymorphism. Veterinary Immunology &
Immunopathology, 144(3-4), 312-320. doi: 10.1016/j.vetimm.2011.08.014
Hock, B. D., Mackenzie, K. A., Cross, N. B., Taylor, K. G., Currie, M. J., Robinson, B. A., Simcock, J. W., McKenzie, J. L. (2012).
Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells. Nephrology Dialysis
Transplantation, 27(1), 402-410. doi: 10.1093/ndt/gfr264
Hock, B. D., Taylor, K. G., Cross, N. B., Kettle, A. J., Hampton, M. B., & McKenzie, J. L. (2012). Effect of activated human
polymorphonuclear leucocytes on T lymphocyte proliferation and viability. Immunology, 137(3), 249-258. doi: 10.1111/
imm.12004
Hodges, B. D., Ginsburg, S., Cruess, R., Cruess, S., Delport, R., Hafferty, F., … Wilkinson, T., Wade, W. (2011). Assessment
of professionalism: Recommendations from the Ottawa 2010 Conference. Medical Teacher, 33(5), 354-363. doi:
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Hoggarth, P., Innes, C., Dalrymple-Alford, J., Croucher, M., Severinsen, J., Gray, J., … Jones, R. (2011). Assessment of older
drivers in New Zealand: The current system, research and recommendations. Australasian Journal on Ageing, 30(3), 148155. doi: 10.1111/j.1741-6612.2010.00478.x
Hollis-Moffatt, J. E., Gow, P. J., Harrison, A. A., Highton, J., Jones, P. B. B., Stamp, L. K., … Merriman, T. R. (2011). The
SLC2A9 nonsynonymous Arg265His variant and gout: Evidence for a population-specific effect on severity. Arthritis
Research & Therapy, 13(3), R85. doi: 10.1186/ar3356
Hollis-Moffatt, J. E., Phipps-Green, A. J., Chapman, B., Jones, G. T., van Rij, A., Gow, P. J., Harrison, A. A., Highton, J., …
Stamp, L. K., … Merriman, T. R. (2012). The renal urate transporter SLC17A1 locus: Confirmation of association with
gout. Arthritis Research & Therapy, 14(2), R92. doi: 10.1186/ar3816
Hooper, G. J., Rothwell, A. G., Frampton, C., & Wyatt, M. C. (2011). Does the use of laminar flow and space suits reduce early
deep infection after total hip and knee replacement? The ten-year results of the New Zealand Joint Registry. Journal of
Bone & Joint Surgery (Br), 93-B(1), 85-90. doi: 10.1302/0301-620X.93B1.24862
Hooper, G. J., Rothwell, A. G., Hooper, N. M., & Frampton, C. (2012). The relationship between the American Society of
Anesthesiologists physical rating and outcome following total hip and knee arthroplasty: An analysis of the New Zealand
Joint Registry. Journal of Bone & Joint Surgery (Am), 94(12), 1065-1070. doi: 10.2106/JBJS.J.01681
Hughes, A. M., Lucas, R. M., Ponsonby, A.-L., …, Taylor, B. V., & et al (2011). The role of latitude, ultraviolet radiation
exposure and vitamin D in childhood asthma and hayfever: An Australian multicenter study. Pediatric Allergy &
Immunology, 22(3), 327-333. doi: 10.1111/j.1399-3038.2010.01099.x
Huising, M. O., Pilbrow, A. P., Matsumoto, M., van der Meulen, T., Park, H., Vaughan, J. M., … Vale, W. W. (2011).
Glucocorticoids differentially regulate the expression of CRFR1 and CRFR2α in MIN6 insulinoma cells and rodent islets.
Endocrinology, 152(1), 138-150. doi: 10.1210/en.2010-0791
Hunt, M. A., Li, D., Hay, M. P., Currie, M. J., Robinson, B. A., Patterson, A. V., & Dachs, G. U. (2012). Characterisation of
enzyme prodrug gene therapy combinations in coated spheroids and vascular networks in vitro. Journal of Gene Medicine,
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Inglis, T., Dalzell, K., Hooper, G., Rothwell, A., & Frampton, C. (2012). Does orthopedic training compromise the outcome in
total hip arthroplasty? Journal of Surgical Education. Advance online publication. doi: 10.1016/j.jsurg.2012.08.003
Innes, C. R. H., Lee, D., Chen, C., Ponder-Sutton, A. M., Melzer, T. R., & Jones, R. D. (2011). Do complex models increase
prediction of complex behaviours? Predicting driving ability in people with brain disorders. Quarterly Journal of
Experimental Psychology, 64(9), 1714-1725. doi: 10.1080/17470218.2011.555821
Jensen, B. P., Chin, P. K. L., & Begg, E. J. (2011). Quantification of total and free concentrations of R- and S-warfarin in human
plasma by ultrafiltration and LC-MS/MS. Analytical & Bioanalytical Chemistry, 401(7), 2187-2193. doi: 10.1007/s00216011-5303-x
Jensen, B. P., Chin, P. K. L., Roberts, R. L., & Begg, E. J. (2012). Influence of adult age on the total and free clearance and
protein binding of (R)- and (S)-warfarin. British Journal of Clinical Pharmacology. Advance online publication. doi:
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Jensen, B. P., Roberts, R. L., Vyas, R., Bonke, G., Jardine, D. L., & Begg, E. J. (2012). Influence of ABCB1 (P-glycoprotein)
haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers.
British Journal of Clinical Pharmacology, 73(4), 619-628. doi: 10.1111/j.1365-2125.2011.04126.x
Jensen, B. P., Vella-Brincat, J. W. A., & Begg, E. J. (2011). Quantification of cyclizine and norcyclizine in human plasma by
liquid chromatography-tandem mass spectrometry (LC-MS/MS). Journal of Chromatography B, 879(9-10), 605-609. doi:
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Pilbrow, A. P., Folkersen, L., Pearson, J. F., Brown, C. M., McNoe, L., Wang, N. M., … Black, M. A., Troughton, R. W., Richards,
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Neurodegeneration, 1(1), 17. doi: 10.1186/2047-9158-1-17
Polasek, T. M., Patel, F., Jensen, B. P., Sorich, M. J., Wiese, M. D., & Doogue, M. P. (2012). Predicted metabolic drug clearance
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Poole, P., Shulruf, B., Rudland, J., & Wilkinson, T. (2012). Comparison of UMAT scores and GPA in prediction of performance
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Poudel, G. R., Innes, C. R. H., & Jones, R. D. (2012). Cerebral perfusion differences between drowsy and nondrowsy
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insulin resistance in the critically ill. Computer Methods & Programs in Biomedicine, 102(2), 172-180. doi: 10.1016/j.
cmpb.2010.08.004
Price, T. J., Zannino, D., Wilson, K., Simes, R. J., Cassidy, J., Van Hazel, G. A., Robinson, B. A., … Tebbutt, N. C. (2012).
Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: A subgroup
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Mitomycin C. Annals of Oncology, 23(6), 1531-1536. doi: 10.1093/annonc/mdr488
Prickett, T. C. R., Bothwell, J. C., Yandle, T. G., Richards, A. M., & Espiner, E. A. (2011). Pharmacodynamic responses of plasma
and tissue C-type natriuretic peptide to GH: Correlation with linear growth in GH-deficient rats. Journal of Endocrinology,
15, 217-225. doi: 10.1530/joe-11-0387
Prickett, T. C. R., Lyver, A., Wilson, R., Espiner, E. A., & Sullivan, M. J. (2012). C-type natriuretic peptide: A novel biomarker of
steroid induced bone toxicity in children with acute lymphoblastic leukemia (ALL). Peptides, 36(1), 54-59. doi: 10.1016/j.
peptides.2012.04.017
Prickett, T. C. R., Olney, R. C., Cameron, V. A., Ellis, M. J., Richards, A. M., & Espiner, E. A. (2012). Impact of age, phenotype
and cardio-renal function on plasma C-type and B-type natriuretic peptide forms in an adult population. Clinical
Endocrinology. Advance online publication. doi: 10.1111/cen.12035
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Rademaker, M. T., Charles, C. J., Ellmers, L. J., Lewis, L. K., Nicholls, M. G., & Richards, A. M. (2011). Prolonged urocortin
2 administration in experimental heart failure: Sustained hemodynamic, endocrine, and renal effects. Hypertension, 57,
1136-1144. doi: 10.1161/HYPERTENSIONAHA.111.173203
Rademaker, M. T., Charles, C. J., Melton, I. C., Richards, A. M., Frampton, C. M., Siou, J., … Troughton, R. W. (2011).
Monitoring of heart failure: Comparison of left atrial pressure with intrathoracic impedance and natriuretic peptide
measurements in an experimental model of ovine heart failure. Clinical Science, 120(5), 207-217. doi: 10.1042/CS20100388
Rademaker, M. T., Charles, C. J., Nicholls, M. G., & Richards, A. M. (2012). Haemodynamic, endocrine and renal actions of
adrenomedullin 5 in an ovine model of heart failure. Clinical Science, 122(9), 429-437. doi: 10.1042/cs20110483
Rademaker, M. T., Charles, C. J., Nicholls, G., & Richards, M. (2011). Urocortin 2 sustains haemodynamic and renal function
during introduction of beta-blockade in experimental heart failure. Journal of Hypertension, 29, 1787-1795. doi: 10.1097/
HJH.0b013e3283493776
Rademaker, M. T., Yandle, T. G., Ellmers, L. J., Charles, C. J., Nicholls, M. G., & Richards, A. M. (2012). Hemodynamic,
hormonal and renal effects of (pro)renin receptor blockade in experimental heart failure. Circulation: Heart Failure, 5,
645-652. doi: 10.1161/circheartfailure.112.967059
Raja, R., Chapman, P. T., O’Donnell, J. L., Ipenburg, J., Frampton, C., Hurst, M., & Stamp, L. K. (2012). Comparison of the
2010 American College of Rheumatology/European League Against Rheumatism and the 1987 American Rheumatism
Association classification criteria for rheumatoid arthritis in an early arthritis cohort in New Zealand. Journal of
Rheumatology, 39(11). doi: 10.3899/jrheum.120226
Ranasinghe, I., Alprandi-Costa, B., Chow, V., Elliott, J. M., Waites, J., Counsell, J. T., … Brieger, D. (2011). Risk stratification
in the setting of non-ST elevation acute coronary syndromes 1999-2007. American Journal of Cardiology, 108(5), 617-624.
doi: 10.1016/j.amjcard.2011.04.005
Reh, C. S., Olney, R. C., Azen, C., Prickett, T. C., Espiner, E. A., & Geffner, M. E. (2012). Plasma C-type natriuretic peptide
forms and thyroid status in prepubertal children with acquired thyroid disease. Clinical Endocrinology, 76(2), 228-235. doi:
10.1111/j.1365-2265.2011.04187.x
Richards, A. M. (2011). Mineralocorticoid receptor antagonists for heart failure. Expert Opinion on Pharmacotherapy, 12(18),
2801-2815. doi: 10.1517/14656566.2011.631524
Richards, A. M., & Troughton, R. W. (2011). Use of natriuretic peptides to guide and monitor heart failure therapy. Clinical
Chemistry, 58(1), 62-71. doi: 10.1373/clinchem.2011.165704
Richardson, A. K., Clarke, G., Sabel, C. E., Pearson, J. F., Mason, D. F., & Taylor, B. V. (2012). Method for identifying eligible
individuals for a prevalence survey in the absence of a disease register or population register. Internal Medicine Journal.
Advance online publication. doi: 10.1111/j.1445-5994.2012.02754.x
Ritzema, J. L., Richards, A. M., Crozier, I. G., Frampton, C., Melton, I. C., Doughty, R. N., … Troughton, R. W. (2011).
Serial Doppler echocardiography and tissue Doppler imaging in the detection of elevated directly measured left atrial
pressure in ambulant subjects with chronic heart failure. JACC: Cardiovascular Imaging, 4(9), 927-934. doi: 10.1016/j.
jcmg.2011.07.004
Rivas, M. A., Beaudoin, M., Gardet, A., Stevens, C., Sharma, Y., Zhang, C. K., … and also Barclay, M., Roberts, R., Gearry, R.
(2011). Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
Nature Genetics, 43(11), 1066-1073. doi: 10.1038/ng.952
Roberts, R. L., & Barclay, M. L. (2012). Current relevance of pharmacogenetics in immunomodulation treatment for Crohn’s
disease. Journal of Gastroenterology & Hepatology, 27(10), 1546-1554. doi: 10.1111/j.1440-1746.2012.07220.x
Roberts, R. L., Gallo, L.-M. D., Barclay, M. L., Gómez-García, M., Cardeña, C., Merriman, T. R., Gearry, R. B., Martin, J.
(2012). Independent replication of an association of CNVR7113.6 with Crohn’s disease in caucasians. Inflammatory Bowel
Diseases, 18(2), 305-311. doi: 10.1002/ibd.21752
Roberts, R. L., Hollis-Moffatt, J. E., Gómez-García, M., Fransen, K., Ponsioen, C. Y., Crusius, B. A., … Merriman, T. R., Barclay,
M. L., Gearry, R. B., Alizadeh, B. Z. (2011). Association of the protein-tyrosine phosphatase nonreceptor type substrate 1
(PTPNS1) gene with inflammatory bowel disease. Inflammatory Bowel Diseases, 17(2), E19-E21. doi: 10.1002/ibd.21470
Rodgers, G. W., Chase, J. G., Roland, T., & MacRae, G. A. (2012). Spectral analysis for a semi-active–passive net-zero base-shear
design concept. Earthquake Engineering & Structural Dynamics, 41(8), 1207-1216. doi: 10.1002/eqe.1177
Rodgers, G. W., Mander, J. B., & Chase, J. G. (2011). Semi-explicit rate-dependent modeling of damage-avoidance steel
connections using HF2V damping devices. Earthquake Engineering & Structural Dynamics, 40(9), 977-992. doi: 10.1002/
eqe.1073
Rodgers, G. W., Solberg, K. M., Mander, J. B., Chase, J. G., Bradley, B. A., & Dhakal, R. P. (2012). High-force-to-volume seismic
dissipators embedded in a jointed precast concrete frame. Journal of Structural Engineering, 138(3), 375-386. doi: 10.1061/
(ASCE)ST.1943-541X.0000329
Ronaldson, J. P., Zainon, R., Scott, N. J. A., Gieseg, S. P., Butler, A. P., Butler, P. H., & Anderson, N. G. (2012). Toward
quantifying the composition of soft tissues by spectral CT with Medipix3. Medical Physics, 39(11), 6847-6857. doi:
10.1118/1.4760773
Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., International Inflammatory Bowel Disease Genetics
Constortium, … and also Roberts, R., Barclay, M., Gearry, R. (2011). Proteins encoded in genomic regions associated with
immune-mediated disease physically interact and suggest underlying biology. PLoS Genetics, 7(1), e1001273. doi: 10.1371/
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223
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Rowe, S., Jordan, J., McIntosh, V., Carter, F., Frampton, C., Bulik, C., & Joyce, P. (2011). Dimensional measures of personality
as a predictor of outcome at 5-year follow-up in women with bulimia nervosa. Psychiatry Research, 185(3), 414-420. doi:
10.1016/j.psychres.2010.07.017
Rozenberg, J., Wieling, W., Schon, I. K., Westerhof, B., Frampton, C., & Jardine, D. (2012). MSNA during prolonged post-faint
hypotension. Clinical Autonomic Research, 22(4), 167-173. doi: 10.1007/s10286-012-0159-5
Rusinaru, D., Tribouilloy, C., Berry, C., Richards, A. M., Whalley, G. A., Earle, N., … on behalf of the MAGGIC Investigators.
(2012). Relationship of serum sodium concentration to mortality in a wide spectrum of heart failure patients with
preserved and with reduced ejection fraction: An individual patient data meta-analysis. European Journal of Heart Failure,
14(10), 1139-1146. doi: 10.1093/eurjhf/hfs099
Saywell, N., Vandal, A. C., Brown, P., Hanger, H. C., Hale, L., Mudge, S., Milosavljevic, S., … Taylor, D. (2012).
Telerehabilitation to improve outcomes for people with stroke: Study protocol for a randomised controlled trial. Trials,
13(1). doi: 10.1186/1745-6215-13-233
Schalkwyk, J. M., Lowes, D., Frampton, C., & Merry, A. F. (2011). Does manual anaesthetic record capture remove clinically
important data? British Journal of Anaesthesia, 107(4), 546-552. doi: 10.1093/bja/aer163
Schouten, B. J., Brownlie, B. E. W., Frampton, C. M., & Turner, J. G. (2011). Subclinical thyrotoxicosis in an outpatient
population: Predictors of outcome. Clinical Endocrinology, 74(2), 257-261. doi: 10.1111/j.1365-2265.2010.03908.x
Schouten, R., Malone, A. A., Tiffen, C., Frampton, C. M., & Hooper, G. (2012). A prospective, randomised controlled trial
comparing ceramic-on-metal and metal-on-metal bearing surfaces in total hip replacement. Journal of Bone & Joint
Surgery (Br), 94(11), 1462-1467. doi: 10.1302/0301-620x.94b11.29343
Schouten, B. J., Prickett, T. C. R., Hooper, A. A., Hooper, G. J., Yandle, T. G., Richards, A. M., & Espiner, E. A. (2011).
Central and peripheral forms of C-type natriuretic peptide (CNP): Evidence for differential regulation in plasma and
cerebrospinal fluid. Peptides, 32(4), 797-804. doi: 10.1016/j.peptides.2011.01.013
Schouten, B. J., Prickett, T. C., Hunt, P. J., Richards, A. M., Geffner, M. E., Olney, R. C., & Espiner, E. A. (2012). C-type
natriuretic peptide forms in adult hyperthyroidism: Correlation with thyroid hormones and markers of bone turnover.
Clinical Endocrinology, 76(6), 790-796. doi: 10.1111/j.1365-2265.2011.04295.x
Schouten, B. J., Raizis, A. M., Soule, S. G., Cole, D. R., Frengley, P. A., George, P. M., & Florkowski, C. M. (2011). Four cases
of autosomal dominant hypocalcaemia with hypercalciuria including two with novel mutations in the calcium-sensing
receptor gene. Annals of Clinical Biochemistry, 48(3), 286-290. doi: 10.1258/acb.2010.010139
Schulz, J. M., Pitcher, T. L., Savanthrapadian, S., Wickens, J. R., Oswald, M. J., & Reynolds, J. N. J. (2011). Enhanced highfrequency membrane potential fluctuations control spike output in striatal fast-spiking interneurones in vivo. Journal of
Physiology, 589(17), 4365-4381. doi: 10.1113/jphysiol.2011.212944
Scott, N. J. A., Cameron, V. A., Raudsepp, S. D., Lewis, L. K., Simpson, E. R., Richards, A. M., & Ellmers, L. J. (2012). Generation
and characterization of a mouse model of the metabolic syndrome: Apolipoprotein E and aromatase double knockout
mice. American Journal of Physiology: Endocrinology & Metabolism, 302, E576-E584. doi: 10.1152/ajpendo.00222.2011
Scott, R., Donoghoe, M., Watts, G. F., O’Brien, R., Pardy, C., Taskinen, M.-R., … Manning, P., … Keech, A. C. (2011). Impact
of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes
assigned to placebo in the FIELD randomised trial. Cardiovascular Diabetology, 10, 102. doi: 10.1186/1475-2840-10-102
Sheehan, D., Wilkinson, T. J., & Bowie, E. (2012). Becoming a practitioner: Workplace learning during the junior doctor’s first
year. Medical Teacher, 34(11), 936-945. doi: 10.3109/0142159x.2012.717184
Shrestha, K., Borowski, A. G., Troughton, R. W., Klein, A. L., & Tang, W. H. W. (2012). Association between systemic neutrophil
gelatinase-associated lipocalin and anemia, relative hypochromia, and inflammation in chronic systolic heart failure.
Congestive Heart Failure, 18(5), 239-244. doi: 10.1111/j.1751-7133.2012.00287.x
Shulruf, B., Poole, P., Wang, G. Y., Rudland, J., & Wilkinson, T. (2012). How well do selection tools predict performance later in
a medical programme? Advances in Health Sciences Education, 17, 615-626. doi: 10.1007/s10459-011-9324-1
Shulruf, B., Turner, R., Poole, P., & Wilkinson, T. (2012). The Objective Borderline method (OBM): A probability-based
model for setting up an objective pass/fail cut-off score in medical programme assessments. Advances in Health Sciences
Education. Advance online publication. doi: 10.1007/s10459-012-9367-y
Silvers, K. M., Frampton, C. M., Wickens, K., Pattemore, P. K., Ingham, T., Fishwick, D., Crane, J., Town, G. I., Epton, M. J.,
on behalf of the New Zealand Asthma and Allergy Cohort Study Group. (2012). Breastfeeding protects against current
asthma up to 6 years of age. Journal of Pediatrics, 160(6), 991-996. doi: 10.1016/j.jpeds.2011.11.055
Singh, J. A., Taylor, W. J., Simon, L. S., Khanna, P. P., Stamp, L. K., McQueen, F. M., … Schumacher, Jr, H. R. (2011). Patientreported outcomes in chronic gout: A report from OMERACT 10. Journal of Rheumatology, 38(7), 1452-1457. doi:
10.3899/jrheum.110271
Sorrenson, B., Suetani, R. J., Bickley, V. M., George, P. M., Williams, M. J. A., Scott, R. S., & McCormick, S. P. A. (2011). An
ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1
mutations. Biochemical & Biophysical Research Communications, 409(3), 400-405. doi: 10.1016/j.bbrc.2011.05.006
Stamp, L. K., Barclay, M. L., O’Donnell, J. L., Zhang, M., Drake, J., Frampton, C., & Chapman, P. T. (2012). Furosemide
increases plasma oxypurinol without lowering serum urate--a complex drug interaction: Implications for clinical practice.
Rheumatology. Advance online publication. doi: 10.1093/rheumatology/kes091
Stamp, L. K., Barclay, M. L., O’Donnell, J. L., Zhang, M., Drake, J., Frampton, C., & Chapman, P. T. (2011). Relationship
between serum urate and plasma oxypurinol in the management of gout: Determination of minimum plasma oxypurinol
concentration to achieve a target serum urate level. Clinical Pharmacology & Therapeutics, 90(3), 392-398. doi: 10.1038/
clpt.2011.113
224
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Stamp, L. K., Barclay, M. L., O’Donnell, J. L., Zhang, M., Drake, J., Frampton, C., & Chapman, P. T. (2011). Effects of changing
from oral to subcutaneous methotrexate on red blood cell methotrexate polyglutamate concentrations and disease activity
in patients with rheumatoid arthritis. Journal of Rheumatology, 38(12), 2540-2547. doi: 10.3899/jrheum.110481
Stamp, L. K., & Chapman, P. T. (2012). Gout and organ transplantation. Current Rheumatology Reports, 14(2), 165-172. doi:
10.1007/s11926-012-0235-9
Stamp, L. K., & Chapman, P. T. (2012). Gout and its comorbidities: Implications for therapy. Rheumatology. Advance online
publication. doi: 10.1093/rheumatology/kes211
Stamp, L. K., & Chapman, P. (2011). Existing and emerging therapies for acute gout and long-term urate lowering. Current
Rheumatology Reviews, 7(2), 141-151. doi: 10.2174/157339711795305031
Stamp, L. K., Hazlett, J., Roberts, R. L., Frampton, C., Highton, J., & Hessian, P. A. (2012). Adenosine receptor expression in
rheumatoid synovium: A basis for methotrexate action. Arthritis Research & Therapy, 14, R138. doi: 10.1186/ar3871
Stamp, L. K., Ipenburg, J., Hurst, M., O’Donnell, J. L., Raja, R., Drake, J., & Chapman, P. T. (2012). The Christchurch
earthquake: Providing a rheumatology service during a natural disaster [Brief report]. Clinical Rheumatology, 31(4), 723725. doi: 10.1007/s10067-011-1913-0
Stamp, L. K., & Jordan, S. (2011). The challenges of gout management in the elderly. Drugs & Aging, 28(8), 591-603. doi:
10.2165/11592750-000000000-00000
Stamp, L. K., Khalilova, I., Tarr, J. M., Senthilmohan, R., Turner, R., Haigh, R. C., … Kettle, A. J. (2012). Myeloperoxidase and
oxidative stress in rheumatoid arthritis. Rheumatology. Advance online publication. doi: 10.1093/rheumatology/kes193
Stamp, L. K., Khanna, P. P., Dalbeth, N., Boers, M., Maksymowych, W. P., Schumacher, Jr, H. R., … Taylor, W. J. (2011). Serum
urate in chronic gout: Will it be the first validated soluble biomarker in rheumatology? Journal of Rheumatology, 38(7),
1462-1466. doi: 10.3899/jrheum.110273
Stamp, L. K., O’Donnell, J. L., Zhang, M., James, J., Frampton, C., Barclay, M. L., & Chapman, P. T. (2011). Using allopurinol
above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including in those with
renal impairment. Arthritis & Rheumatism, 63(2), 412-421. doi: 10.1002/art.30119
Stamp, L. K., & Roberts, R. L. (2011). Effect of genetic polymorphisms in the folate pathway on methotrexate therapy in
rheumatic diseases. Pharmacogenomics, 12(10), 1449-1463. doi: 10.2217/pgs.11.86
Stamp, L. K., Taylor, W. J., Jones, P. B., Dockerty, J. L., Drake, J., Frampton, C., & Dalbeth, N. (2012). Starting dose is a risk
factor for allopurinol hypersensitivity syndrome: A proposed safe starting dose of allopurinol. Arthritis & Rheumatism,
64(8), 2529-2536. doi: 10.1002/art.34488
Stamp, L. K., Zhu, X., Dalbeth, N., Jordan, S., Edwards, N. L., & Taylor, W. (2011). Serum urate as a soluble biomarker in
chronic gout: Evidence that serum urate fulfills the OMERACT validation criteria for soluble biomarkers. Seminars in
Arthritis & Rheumatism, 40(6), 483-500. doi: 10.1016/j.semarthrit.2010.09.003
Stoner, L., Young, J. M., & Fryer, S. (2012). Assessments of arterial stiffness and endothelial function using pulse wave analysis.
International Journal of Vascular Medicine, 2012, 903107. doi: 10.1155/2012/903107
Storer, M. K., Dummer, J. D., Cook, J., McEwan, M., & Epton, M. J. (2011). Increased concentrations of breath haloamines
are not detectable in airways inflammation using SIFT-MS. Journal of Breath Research, 5(3). doi: 10.1088/17527155/5/3/037105
Storer, M., Dummer, J., Lunt, H., Scotter, J., McCartin, F., Cook, J., Swanney, M., … Epton, M. (2011). Measurement of breath
acetone concentrations by selected ion flow tube mass spectrometry in type 2 diabetes. Journal of Breath Research, 5,
046011. doi: 10.1088/1752-7155/5/4/046011
Sundaresan, A., Chase, J. G., Hann, C. E., & Shaw, G. M. (2011). Dynamic functional residual capacity can be estimated using a
stress-strain approach. Computer Methods & Programs in Biomedicine, 101(2), 135-143. doi: 10.1016/j.cmpb.2010.05.005
Sundaresan, A., Chase, J. G., Shaw, G. M., Chiew, Y. S., & Desaive, T. (2011). Model-based optimal PEEP in mechanically
ventilated ARDS patients in the Intensive Care Unit. BioMedical Engineering OnLine, 10, 64. doi: 10.1186/1475-925x-10-64
Swaminathan, A., Lunt, H., Chang, W. S. J., Logan, F. J., Frampton, C. M. A., & Florkowski, C. M. (2012). Impact of prandial
status on the comparison of capillary glucose meter and venous plasma glucose measurements in healthy volunteers.
Annals of Clinical Biochemistry. Advance online publication. doi: 10.1258/acb.2012.012084
Sykes, P., Vaughan, M., Chrystal, K., Ehrenberg, N., Hefford, M., Hutchings, S., … Ngan Kee, D. (2012). Providing care for
women with gynaecological malignancy: The need for a coordinated national approach. New Zealand Medical Journal,
125(1360). Retrieved from http://journal.nzma.org.nz/journal/125-1360/5309/content.pdf.
Tanpowpong, P., Ingham, T. R., Lampshire, P. K., Kirchberg, F. F., Epton, M. J., Crane, J., … and the New Zealand Asthma and
Allergy Cohort Study Group, including Pattemore, P., Siebers, R., Wickens, K. (2012). Coeliac disease and gluten avoidance
in New Zealand children. Archives of Disease in Childhood, 97, 12-16. doi: 10.1136/archdischild-2011-300248
Taylor, W. J., Singh, J. A., Saag, K. G., Dalbeth, N., MacDonald, P. A., Edwards, N. L., … Stamp, L. K., … Schumacher, Jr, H. R.
(2011). Bringing it all together: A novel approach to the development of response criteria for chronic gout clinical trials.
Journal of Rheumatology, 38(7), 1467-1470. doi: 10.3899/jrheum.110274
Than, M., Cullen, L., Aldous, S., Parsonage, W. A., Reid, C. M., Greenslade, J., … Ardagh, M. W., Troughton, R., … Richards,
A. M. (2012). 2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary
troponins as the only biomarker: The ADAPT trial. JACC, 59(23), 2091-2098. doi: 10.1016/j.jacc.2012.02.035
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Zhang, M., Moore, G. A., Jensen, B. P., Begg, E. J., & Bird, P. A. (2011). Determination of dexamethasone and dexamethasone
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Zhi, J., Chen, E., Major, P., Burns, I., Robinson, B., McKendrick, J., … Goldstein, D. (2011). A multicenter, randomized, openlabel study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients
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Journal - Research Other
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Aldous, S., Pemberton, C., Troughton, R., Than, M., & Richards, A. M. (2012). Heart fatty acid binding protein and myoglobin
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Bridgman, P. G., Chan, C. W., & Elliott, J. M. (2012). A case of recurrent earthquake stress cardiomyopathy with a differing
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Chin, P. K. L., Vella-Brincat, J. W. A., Barclay, M. L., & Begg, E. J. (2012). Perspective on dabigatran etexilate dosing: Why not
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Gearry, R. B., & Falvey, J. D. (2012). Rescue therapy for steroid refractory acute severe ulcerative colitis: more choice, better
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Hayes, J. M., & Ding, S. L. (2012). Pancreatic stone and treatment using ERCP and ESWL procedures: A case study and
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Hsu, A., Dalbeth, N., Gow, P., Harrison, A., Highton, J., Jones, P. B., Stamp, L. K., Merriman, T. R. (2012). No evidence for
association of Chr 9p21 variant rs1333049 with gout in New Zealand case-control sample sets [Letter to the editor].
Rheumatology, 51, 1129-1130. doi: 10.1093/rheumatology/kes029
Kennedy, M. A., Joyce, P. R., & Begg, E. J. (2012). Institutional Profile: The Carney Centre for Pharmacogenomics: A New
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Khan, A. R., Chapman, P. T., Stamp, L. K., Wells, J. E., & O’Donnell, J. L. (2012). Wegener’s granulomatosis: Treatment and
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Lacey, C., Huria, T., Beckert, L., Gillies, M., & Pitama, S. (2011). The Hui Process: A framework to enhance the doctor–patient
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Lewis, D. R., Buckenham, T., & Yeo, Y. E. (2011). A rare case of brachial artery fibromuscular dysplasia (FMD)
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MacAskill, M. R., Koga, K., & Anderson, T. J. (2011). Japanese street performer mimes violation of Hering’s Law. Neurology, 76,
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McNally, A., Pithie, A., & Jardine, D. (2012). Cefepime: A rare cause of encephalopathy. Internal Medicine Journal, 42(6), 732733. doi: 10.1111/j.1445-5994.2012.02800.x
Md Ralib, A., Pickering, J. W., & Endre, Z. H. (2011). Predictor of early diagnosis, diagnosis, or progression of acute kidney
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Meijer, B., Gearry, R. B., & Day, A. S. (2012). S100A12 in EDTA plasma: A cautionary tale [Letter to the editor]. Journal of
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Moller, P. (2011). Excess winter mortality, wood fires and the uncertainties associated with air pollutants [Viewpoint]. New
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Moller, P. W. (2011). Comment on Government response to air pollution articles [Letter]. New Zealand Medical Journal,
124(1338). Retrieved from http://journal.nzma.org.nz/journal/124-1338/4768/content.pdf.
Moore, M., & Grundy, K. (2011). CPR in New Zealand hospitals: An alternate perspective on lawfulness and ways to
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Ngu, J. H., Gearry, R. B., & Stedman, C. A. M. (2012). Has primary sclerosing cholangitis associated with Crohn’s disease a
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Nicholls, M. G. (2011). Population-wide dietary sodium restriction: A cautious view [Invited commentary]. Current
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Palmer, S., Craig, J., & Strippoli, G. F. M. (2011). In reply to Mortality in chronic kidney disease and mineral metabolism [Letter
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Palmer, S. C., & Strippoli, G. F. M. (2011). Cardiovascular diseases: Lipid-lowering in CKD: At the SHARP end of the evidence?
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Pearson, S., Troughton, R., & Richards, A. M. (2011). Rivaroxaban versus warfarin in nonvalvular atrial fibrillation [Letter to
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Pemberton, C. J., Richards, A. M., Siriwardena, M., Cameron, V. A., Yandle, T. G., Nicholls, M. G., Kleffmann, T., Ruygrok, P.
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Phipps-Green, A., McKinney, C., Rossol, M., Merriman, M. E., Topless, R., Hollis-Moffatt, J. E., Wan Taib, W. R., … Harrison,
A. A., Highton, J., … Stamp, L. K., … Merriman, T. R. (2011). Analysis of association of DNASE2 promoter variation with
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Pickering, J. W., & Endre, Z. H. (2011). Baseline creatinine: Where to from here? [Letter to the editor]. Nephrology Dialysis
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Pickering, J. W., Md Ralib, A., & Endre, Z. H. (2011). Was it the nephrologists or the fluid? [Letter to the editor]. American
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Pitama, S., Cameron, V., Huria, T., Tikao-Mason, K., Faatoese, A., & Whalley, G. (2011). Adjusting protocols in clinical
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Pitama, S., Huria, T., Beckert, L., & Lacey, C. (2011). Assessing the assessment: Cultural competence and understandings
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Prescott, H., Ellis, E., & Soule, S. (2011). Pituitary infarction: A potentially fatal cause of postoperative hyponatraemia and
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Richards, M. (2012). Biomarkers and silent cardiac disease in primary prevention: Time to unmask the damage? [Editorial
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Richards, A. M., Lam, C., Wong, R. C., & Ping, C. (2011). Heart failure: A problem of our age [Editorial]. Annals of the
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Sheerin, I., Pitama, S., Wells, J. E., Faatoese, A., Richards, M., Troughton, R., Tikao-Mason, K., Huria, T., Robertson, P., Gillies,
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Siriwardena, M., Campbell, V., Richards, A. M., & Pemberton, C. J. (2012). Cardiac biomarker responses to dobutamine stress
echocardiography in healthy volunteers and patients with coronary artery disease [Letter to the editor]. Clinical Chemistry,
58(10), 1492-1494. doi: 10.1373/clinchem.2012.187682
Stamp, L. K., Harrison, A., Frampton, C., & Corkill, M. M. (2012). Does a joint count calibration exercise make a difference?
Implications for clinical trials and training [Letter to the editor]. Journal of Rheumatology, 39(4), 877-878. doi: 10.3899/
jrheum.111224
Tan, P., Lee, C., & Beckert, L. (2012). Biological glue for persistent airleak: A case report. New Zealand Medical Journal,
125(1359). Retrieved from http://journal.nzma.org.nz/journal/125-1359/5280/content.pdf.
Troughton, R. W., & Nicholls, M. G. (2011). B-type natriuretic peptide or amino-terminal pro-B-type natriuretic peptideguided treatment of heart failure: What is the next STEP? [Editorial]. European Journal of Heart Failure, 13(10), 1046-1048.
doi: 10.1093/eurjhf/hfr117
229
RESEARCH REPORT 2011/2012
Turner, R., Stamp, L. K., & Kettle, A. J. (2012). Detection of allantoin in clinical samples using hydrophilic liquid
chromatography with stable isotope dilution negative ion tandem mass spectrometry [Short communication]. Journal of
Chromatography B, 891-892, 85-89. doi: 10.1016/j.jchromb.2012.02.009
Vella-Brincat, J., McKean, A., & Barclay, M. (2011). Clozapine-induced gastrointestinal hypomotility [Letter]. Australasian
Psychiatry, 19(5), 450-451. doi: 10.3109/10398562.2011.610462
Wells, J. E., Cross, N. B., & Richardson, A. K. (2012). Toxicity profile of lithium [Letter]. Lancet, 379(9834), 2338. doi: 10.1016/
s0140-6736(12)61012-5
Wieling, W., Rozenberg, J., Schon, I. K., Karemaker, J. M., Westerhof, B. E., & Jardine, D. L. (2011). Prolonged post-faint
hypotension can be reversed by dynamic tension [Case report]. Clinical Autonomic Research, 21(6), 415-418. doi: 10.1007/
s10286-011-0133-7
Wilkinson, T. (2011). Pass/fail grading: Not everything that counts can be counted [Commentary]. Medical Education, 45(9),
860-862. doi: 10.1111/j.1365-2923.2011.04018.x
Wilkinson, T. J., Moore, M., & Flynn, E. M. (2012). Professionalism in its time and place: Some implications for medical
education [Viewpoint]. New Zealand Medical Journal, 125(1358). Retrieved from http://journal.nzma.org.nz/
journal/125-1358/5262/content.pdf.
Journal - Professional & Other Non-Research Articles
Aldous, S., Pemberton, C., Richards, A. M., Troughton, R., & Than, M. (2012). Authors’ response [Letter]. Emergency Medicine
Journal, 29(7), 601-602. doi: 10.1136/emermed-2012-201216
Bentley, R. W., Keown, D., Merriman, T. R., Krishnan, M. R., Gearry, R. B., Barclay, M. L., Roberts, R. L., Day, A. S. (2011).
Vitamin D receptor gene polymorphism associated with inflammatory bowel disease in New Zealand males [Letter to the
editor]. Alimentary Pharmacology & Therapeutics, 33(7), 855-856. doi: 10.1111/j.1365-2036.2011.04588.x
Gearry, R. B. (2011). [Review of the book Clinical gastroenterology: A practical problem based approach (3rd edition)]. New
Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.nz/journal/124-1340/4819/content.pdf.
Moller, P. W. (2011). Wood burning and air pollution [Letter]. New Zealand Medical Journal, 124(1331). Retrieved from http://
journal.nzma.org.nz/journal/124-1331/4596/content.pdf.
Ngu, J. H., Gearry, R. B., & Stedman, C. A. M. (2012). [Reply to letter to the editor Primary sclerosing cholangitis: The gut-liver
axis]. Clinical Gastroenterology & Hepatology, 10(7), 819-820. doi: 10.1016/j.cgh.2012.04.006
Palmer, S. C., Sciancalepore, M., & Strippoli, G. F. M. (2011). Trial quality in nephrology: How are we measuring up?
[Editorial]. American Journal of Kidney Diseases, 58(3), 335-337. doi: 10.1053/j.ajkd.2011.06.006
Pickering, J. W. (2011). Survivor bias in early- vs late-start hemodialysis studies [Letter]. Archives of Internal Medicine, 171(5),
477. doi: 10.1001/archinternmed.2011.55
Shulruf, B., Poole, P., Wang, G. Y., Rudland, J., & Wilkinson, T. (2012). Some light in the fog? [Reply to commentary]. Advances
in Health Sciences Education, 17(5), 631-632. doi: 10.1007/s10459-012-9413-9
Strippoli, G. F. M., Palmer, S. C., & Craig, J. C. (2012). [Reply to letter to the editor Effects of antiplatelet therapy on mortality and
cardiovascular and bleeding outcomes in persons with chronic kidney disease]. Annals of Internal Medicine, 157(4), 303-304.
Than, M., Cullen, L., Reid, C. M., Lim, S. H., & Richards, M. (2011). Rapid diagnostic protocol for patients with chest pain:
Authors’ reply [Letter]. Lancet, 378(9789), 398-399. doi: 10.1016/S0140-6736(11)61206-3
Wilkinson, T. J. (2012). Making sense of work-based assessments [Letter to the editor]. Medical Education, 46(4), 436. doi:
10.1111/j.1365-2923.2011.04202.x
Intellectual Property
Prickett, T. C. R., Espiner, E. A., Richards, A. M., Yandle, T. G., & Nicholls, M. G. (2011). Assessment of skeletal growth using
measurements of NT-CNP peptides. (US 7,919,255).
Commissioned Report for External Body
National Advance Care Planning Cooperative, including Grundy, K., & Moore, M. (2011). Advance care planning: A guide
for the New Zealand health care workforce. Commissioned by Ministry of Health. Wellington, New Zealand: Ministry of
Health. 30p.
Rothwell, A., Hobbs, T., & Frampton, C. (2012). The New Zealand Joint Registry: Thirteen year report: January 1999 to
December 2011. Commissioned by New Zealand Orthopaedic Association. 149p.
Awarded Doctoral Degree
Melzer, T. R. (2011). Magnetic resonance imaging of cognition in Parkinson’s disease (PhD). University of Otago, Christchurch,
New Zealand. 185p.
230
RESEARCH REPORT 2011/2012
University of Otago, Christchurch
Obstetrics & Gynaecology
Journal - Research Article
Bru-Mercier, G., Gullam, J. E., Thornton, S., Blanks, A. M., & Shmygol, A. (2012). Characterization of the tissue-level Ca2+
signals in spontaneously contracting human myometrium. Journal of Cell & Molecular Biology, 16(12), 2990-3000. doi:
10.1111/j.1582-4934.2012.01626.x
Chitcholtan, K., Asselin, E., Parent, S., Sykes, P. H., & Evans, J. J. (2012). Differences in growth properties of endometrial cancer
in three dimensional (3D) culture and 2D cell monolayer. Experimental Cell Research. Advance online publication. doi:
10.1016/j.yexcr.2012.09.012
Chitcholtan, K., Harris, E., Yu, Y., Harland, C., & Garrill, A. (2012). An investigation into plasmolysis in the oomycete Achlya
bisexualis reveals that membrane-wall attachment points are sensitive to peptides containing the sequence RGD and that
cell wall deposition can occur despite retraction of the protoplast. Canadian Journal of Microbiology, 58(10), 1212-1220.
doi: 10.1139/w2012-099
Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are
distinct in 3D and 2D endometrial cancer. Journal of Translational Medicine, 10(1), 38-53. doi: 10.1186/1479-5876-10-38
Evans, J. J., & Anderson, G. M. (2012). Balancing ovulation and anovulation: Integration of the reproductive and energy
balance axes by neuropeptides. Human Reproduction Update, 18(3), 313-332. doi: 10.1093/humupd/dms004
Evans, J. J., & Chitcholtan, K. (2011). Extracellular matrix proteins in the anterior pituitary gland. Open Neuroendocrinology
Journal, 4, 111-119. doi: 10.2174/1876528901104010111
Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin
interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic
Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429
Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Simón, C., McNoe, L. A., Sykes, P. H., … Evans, J. J. (2012).
Gene and protein expression signature of endometrial glandular and stromal compartments during the window of
implantation. Fertility & Sterility, 97(6), 1365-1373. doi: 10.1016/j.fertnstert.2012.03.007
Evans, G. E., Phillipson, G. T. M., Sin, I. L., Frampton, C. M. A., Kirker, J. A., Bigby, S. M., & Evans, J. J. (2012). Gene expression
confirms a potentially receptive endometrium identified by histology in fertile women. Human Reproduction, 27(9), 27472755. doi: 10.1093/humrep/des233
Ibrahim, S. N., Murray, L., Evans, J. J., & Alkaisi, M. M. (2012). Trapping single cells: Comparison between sandwiched
insulation with back contact (SIBC) and planar biochip. Materials Science Forum, 700, 188-194. doi: 10.4028/www.
scientific.net/MSF.700.188
Ibrahim, S. N., Murray, L., Nock, V., Evans, J. J., & Alkaisi, M. M. (2012). The quadrupole microelectrode design on a
multilayer biochip for dielectrophoretic trapping of single cells. Microelectronic Engineering. Advance online publication.
doi: 10.1016/j.mee.2012.04.018
Kondalsamy-Chennakesavan, S., Yu, C., Kattan, M. W., Leung, Y., Sykes, P., Nascimento, M., … Obermair, A. (2012).
Nomograms to predict isolated loco-regional or distant recurrence among women with uterine cancer. Gynecologic
Oncology, 125(3), 520-525. doi: 10.1016/j.ygyno.2012.02.022
McAllum, B., Sykes, P. H. H., Sadler, L., MacNab, H., Simcock, B. J., & Mekhail, A. K. (2011). Is the treatment of CIN 2
always necessary in women under 25? American Journal of Obstetrics & Gynecology, 205(5), 478.e1-478.e7. doi: 10.1016/j.
ajog.2011.06.069
McLeod, M., Cormack, D., Harris, R., Robson, B., Sykes, P., & Crengle, S. (2011). Achieving equitable outcomes for Mäori
women with cervical cancer in New Zealand: Health provider views. New Zealand Medical Journal, 124(1334). Retrieved
from http://journal.nzma.org.nz/journal/124-1334/4661/content.pdf.
Nock, V., Murray, L., Samsuri, F., Alkaisi, M. M., & Evans, J. J. (2011). Microfluidic arrays for bioimprint of cancer cells.
Microelectronic Engineering, 88(8), 1828-1831. doi: 10.1016/j.mee.2010.12.042
Obermair, A., Mileshkin, L., Bolz, K., Kondalsamy-Chennakesavan, S., Cheuk, R., Vasey, P., … Sykes, P., Janda, M.
(2011). Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical
pelvic radiotherapy for uterine papillary serous carcinoma. Gynecologic Oncology, 120(2), 179-184. doi: 10.1016/j.
ygyno.2010.10.039
Samsuri, F., Alkaisi, M. M., Evans, J. J., Chitcholtan, K., & Mitchell, J. S. (2011). Detection of changes in cell membrane
structures using the Bioimprint technique. Microelectronic Engineering, 88(8), 1871-1874. doi: 10.1016/j.mee.2010.12.069
Sykes, P., Vaughan, M., Chrystal, K., Ehrenberg, N., Hefford, M., Hutchings, S., … Ngan Kee, D. (2012). Providing care for
women with gynaecological malignancy: The need for a coordinated national approach. New Zealand Medical Journal,
125(1360). Retrieved from http://journal.nzma.org.nz/journal/125-1360/5309/content.pdf.
Yoshida, A., Chitcholtan, K., Evans, J. J., Nock, V., & Beasley, S. W. (2011). In vitro tissue engineering of smooth muscle
sheets with peristalsis using a murine induced pluripotent stem cell line. Journal of Pediatric Surgery, 47(2), 329-335. doi:
10.1016/j.jpedsurg.2011.11.027
Journal - Research Other
Evans, J. J. (2011). The anterior pituitary gland: Co-ordinating an alphabet of peptides [Editorial]. Open Neuroendocrinology
Journal, 4, 22-24. doi: 10.2174/1876528901104010022
231
RESEARCH REPORT 2011/2012
Sykes, P. H., McAllum, B. E., Simcock, B., & Sadler, L. (2012). [Reply to letter to the editor Initial diagnosis of CIN 2—should
patients be managed expectatively?]. American Journal of Obstetrics & Gynecology, 206(3), e11-e12. doi: 10.1016/j.
ajog.2011.11.004
Walker, N. H., Sabanli, M., Sykes, P. H., Russell, P., & Perez, D. (2012). Successful reproductive outcome following treatment of
advanced small cell carcinoma of the ovary [Case report]. Gynecologic Oncology Case Reports, 2(3), 115-117. doi: 10.1016/j.
gynor.2012.06.001
Journal - Professional & Other Non-Research Articles
Reid, R. (2011). [Review of the book Obstetrics and gynaecology: The essentials of clinical care]. New Zealand Medical Journal,
124(1328). Retrieved from http://journal.nzma.org.nz/journal/124-1328/4522/content.pdf.
Sykes, P. H., McAllum, B., Simcock, B., & Sadler, L. (2012). [Reply to letter to the editor Initial diagnosis of CIN 2–should
patients be managed expectatively?]. American Journal of Obstetrics & Gynecology, 206(3), e11-e12. doi: 10.1016/j.
ajog.2011.11.004
Commissioned Report for External Body
Evans, J., Tan, T., & Chitcholtan, K. (2011). Anticancer effects of seaweed extracts on endometrial cancer cells. Commissioned by
Leanne Bramley of Sustainable Seafood NZ Ltd. New Zealand: Laboratory of Cell and Protein Regulation, Department of
Obstetrics and Gynaecology, University of Otago, Christchurch. 20p.
Awarded Doctoral Degree
Gullam, J. E. (2011). Analysis of mechanisms mediating the oxytocin-induced stimulation of human myometrium (MD).
University of Warwick, Coventry, UK.
University of Otago, Christchurch
Orthopaedic Surgery & Musculoskeletal Medicine
Chapter in Book - Research
Melchels, F., Malda, J., Fedorovich, N., Alblas, J., & Woodfield, T. (2011). Organ printing. In P. Ducheyne, K. E. Healy, D. W.
Hutmacher, D. W. Grainger, & C. J. Kirkpatrick (Eds.), Comprehensive biomaterials (vol. 5) (pp. 587-606). Elsevier Science.
Thompson, B. (2012). Abductive reasoning and case formulation in complex cases. In L. Robertson (Ed.), Clinical reasoning in
occupational therapy: Controversies in practice (pp. 15-30). Chichester, UK: Wiley-Blackwell.
Journal - Research Article
Ardagh, M. W., Richardson, S. K., Robinson, V., Than, M., Gee, P., Henderson, S., … McKie, J., Robertson, G., … Deely, J. M.
(2012). The initial health-system response to the earthquake in Christchurch, New Zealand, in February, 2011. Lancet, 379,
2109-2115. doi: 10.1016/s0140-6736(12)60313-4
Bacht, T., Chase, J. G., MacRae, G., Rodgers, G. W., Rabczuk, T., Dhakal, R. P., & Desombre, J. (2011). HF2V dissipator effects
on the performance of a 3 story moment frame. Journal of Constructional Steel Research, 67(12), 1843-1849. doi: 10.1016/j.
jcsr.2011.05.007
Charlifue, S., Post, M. W., Biering-Sørensen, F., Catz, A., Dijkers, M., Geyh, S., … Sinnott, K. A. (2012). International spinal
cord injury quality of life basic data set. Spinal Cord, 50(9), 672-675. doi: 10.1038/sc.2012.27
Desombre, J., Rodgers, G. W., MacRae, G. A., Rabczuk, T., Dhakal, R. P., & Chase, J. G. (2011). Experimentally validated FEA
models of HF2V damage free steel connections for use in full structural analyses. Structural Engineering & Mechanics,
37(4).
Dunn, J. A., Hay-Smith, E. J. C., Whitehead, L. C., & Keeling, S. (2012). Issues influencing the decision to have upper limb
surgery for people with tetraplegia. Spinal Cord. Advance online publication. doi: 10.1038/sc.2012.58
Dunn, J. A., Hay-Smith, E. J. C., Whitehead, L. C., & Keeling, S. (2012). Liminality and decision making for upper
limb surgery in tetraplegia: A grounded theory. Disability & Rehabilitation. Advance online publication. doi:
10.3109/09638288.2012.727945
Emans, P. J., Jansen, E. J. P., van Iersel, D., Welting, T. J. M., Woodfield, T. B. F., Bulstra, S. K., … Kuijer, R. (2012). Tissueengineered constructs: The effect of scaffold architecture in osteochondral repair. Journal of Tissue Engineering &
Regenerative Medicine. Advance online publication. doi: 10.1002/term.1477
Gilchrist, N., Hooper, G., Frampton, C., Maguire, P., Heard, A., March, R. L., Maxwell, R., Penny, I. (2012). Measurement of
bone density around the Oxford medial compartment knee replacement using iDXA: A precision study. Journal of Clinical
Densitometry. Advance online publication. doi: 10.1016/j.jocd.2012.02.015
Graves, S. E., Rothwell, A., Tucker, K., Jacobs, J. J., & Sedrakyan, A. (2011). A multinational assessment of metal-on-metal
bearings in hip replacement. Journal of Bone & Joint Surgery (Am), 93(Suppl. 3), 43-47. doi: 10.2106/JBJS.K.01220
Hay-Smith, E. J. C., Dickson, B., Nunnerley, J., & Sinnott, K. A. (2012). “The final piece of the puzzle to fit in”: An
interpretative phenomenological analysis of the return to employment in New Zealand after spinal cord injury. Disability
& Rehabilitation. Advance online publication. doi: 10.3109/09638288.2012.737079
Hooper, G. J., Rothwell, A. G., Frampton, C., & Wyatt, M. C. (2011). Does the use of laminar flow and space suits reduce early
deep infection after total hip and knee replacement? The ten-year results of the New Zealand Joint Registry. Journal of
Bone & Joint Surgery (Br), 93-B(1), 85-90. doi: 10.1302/0301-620X.93B1.24862
232
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Hooper, G. J., Rothwell, A. G., Hooper, N. M., & Frampton, C. (2012). The relationship between the American Society of
Anesthesiologists physical rating and outcome following total hip and knee arthroplasty: An analysis of the New Zealand
Joint Registry. Journal of Bone & Joint Surgery (Am), 94(12), 1065-1070. doi: 10.2106/JBJS.J.01681
Hornibrook, J., Coates, M., Goh, A., Gourley, J., & Bird, P. (2012). Magnetic resonance imaging for Ménière’s disease:
Correlation with tone burst electrocochleography. Journal of Laryngology & Otology, 126, 136-141. doi: 10.1017/
S0022215111003112
Inglis, T., Dalzell, K., Hooper, G., Rothwell, A., & Frampton, C. (2012). Does orthopedic training compromise the outcome in
total hip arthroplasty? Journal of Surgical Education. Advance online publication. doi: 10.1016/j.jsurg.2012.08.003
Kempthorne, J. T., Armour, P. C., Rietveld, J. A., & Hooper, G. J. (2011). Surgical dislocation of the hip and the management
of femoroacetabular impingement: Results of the Christchurch experience. ANZ Journal of Surgery, 81(6), 446-450. doi:
10.1111/j.1445-2197.2010.05489.x
Kirkland, N. T., Kolbeinsson, I., Woodfield, T., Dias, G. J., & Staiger, M. P. (2011). Synthesis and properties of topologically
ordered porous magnesium. Materials Science & Engineering: B, 176(20), 1666-1672. doi: 10.1016/j.mseb.2011.04.006
Kirkland, N. T., Waterman, J., Birbilis, N., Dias, G., Woodfield, T. B. F., Hartshorn, R. M., & Staiger, M. P. (2012). Bufferregulated biocorrosion of pure magnesium. Journal of Materials Science: Materials in Medicine, 23, 283-291. doi: 10.1007/
s10856-011-4517-y
Lee, A. J.-J., Raniga, S., Hooper, G., Perry, A., Bisset, R., Darley, D., & Hurley-Watts, C. (2012). The Time Out Procedure:
Have we changed our practice? New Zealand Medical Journal, 125(1362). Retrieved from http://journal.nzma.org.nz/
journal/125-1362/5352/content.pdf.
MacVicar, J., Borowczyk, J. M., MacVicar, A. M., Loughnan, B. M., & Bogduk, N. (2012). Cervical medial branch
radiofrequency neurotomy in New Zealand. Pain Medicine, 13(5), 647-654. doi: 10.1111/j.1526-4637.2012.01351.x
Malone, A. A., Sanchez, J. S., Adams, R., & Morrey, B. (2012). Revision of total elbow replacement by exchange cementing.
Journal of Bone & Joint Surgery (Br), 94-B(1), 80-85. doi: 10.1302/0301-620X.94B1.26004
Molony, D. C., & Mohammed, K. D. (2011). The Superior Labral Anterior to Posterior (SLAP) lesion: An elusive pathology.
New Zealand Journal of Sports Medicine, 38(3), 72-79.
Murray, L. M., Nock, V., Alkaisi, M. M., Lee, J. J. M., & Woodfield, T. B. F. (2012). Fabrication of polymeric substrates with
micro- and nanoscale topography bioimprinted at progressive cell morphologies. Journal of Vacuum Science & Technology
B: Microelectronics & Nanometer Structures, 30(6), 06F902. doi: 10.1116/1.4758759
Nguyen, T. L., Blanquet, A., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2012). On the role of surface roughness in the
corrosion of pure magnesium in vitro. Journal of Biomedical Materials Research Part B, 100 B(5), 1310-1318.
Nguyen, T. L., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2011). A novel manufacturing route for fabrication of
topologically-ordered porous magnesium scaffolds. Advanced Engineering Materials, 13(9), 872-881. doi: 10.1002/
adem.201100029
Nguyen, T., Waterman, J., Staiger, M., & Woodfield, T. (2012). Controlling in vitro corrosion rate of pure Mg with rough
surface texture via biomimetic coating systems. Corrosion Engineering, Science & Technology, 47(5), 358-364. doi:
10.1179/1743278212y.0000000023
Noorani, A. M., Roberts, D. J. S., Malone, A. A., Waters, T. S., Jaggi, A., Lambert, S. M., & Bayley, I. (2012). Validation of
the Stanmore percentage of normal shoulder assessment. International Journal of Shoulder Surgery, 6(1), 9-14. doi:
10.4103/0973-6042.94307
Pearse, A. J., Hooper, G. J., Rothwell, A. G., & Frampton, C. (2012). Osteotomy and unicompartmental knee arthroplasty
converted to total knee arthroplasty: Data from the New Zealand Joint Registry. Journal of Arthroplasty, 27(10), 1827-1831.
doi: 10.1016/j.arth.2012.05.031
Rasmussen, J. V., Olsen, B. S., Fevang, B.-T. S., Furnes, O., Skytta, E. T., Rahme, H., … Mohammed, K. D. (2012). A review of
national shoulder and elbow joint replacement registries. Journal of Shoulder & Elbow Surgery. Advance online publication.
doi: 10.1016/j.jse.2012.03.004
Rodgers, G. W., Chase, J. G., Roland, T., & MacRae, G. A. (2012). Spectral analysis for a semi-active–passive net-zero base-shear
design concept. Earthquake Engineering & Structural Dynamics, 41(8), 1207-1216. doi: 10.1002/eqe.1177
Rodgers, G. W., Mander, J. B., & Chase, J. G. (2011). Semi-explicit rate-dependent modeling of damage-avoidance steel
connections using HF2V damping devices. Earthquake Engineering & Structural Dynamics, 40(9), 977-992. doi: 10.1002/
eqe.1073
Rodgers, G. W., Solberg, K. M., Mander, J. B., Chase, J. G., Bradley, B. A., & Dhakal, R. P. (2012). High-force-to-volume seismic
dissipators embedded in a jointed precast concrete frame. Journal of Structural Engineering, 138(3), 375-386. doi: 10.1061/
(ASCE)ST.1943-541X.0000329
Rolfson, O., Rothwell, A., Sedrakyan, A., Chenok, K. E., Bohm, E., Bozic, K. J., & Garellick, G. (2011). Use of patient-reported
outcomes in the context of different levels of data. Journal of Bone & Joint Surgery (Am), 93(Suppl. 3), 66-71. doi: 10.2106/
JBJS.K.01021
Schouten, R., Malone, A. A., Tiffen, C., Frampton, C. M., & Hooper, G. (2012). A prospective, randomised controlled trial
comparing ceramic-on-metal and metal-on-metal bearing surfaces in total hip replacement. Journal of Bone & Joint
Surgery (Br), 94(11), 1462-1467. doi: 10.1302/0301-620x.94b11.29343
Schouten, B. J., Prickett, T. C. R., Hooper, A. A., Hooper, G. J., Yandle, T. G., Richards, A. M., & Espiner, E. A. (2011).
Central and peripheral forms of C-type natriuretic peptide (CNP): Evidence for differential regulation in plasma and
cerebrospinal fluid. Peptides, 32(4), 797-804. doi: 10.1016/j.peptides.2011.01.013
233
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Stamp, L. K., Barclay, M. L., O’Donnell, J. L., Zhang, M., Drake, J., Frampton, C., & Chapman, P. T. (2011). Effects of changing
from oral to subcutaneous methotrexate on red blood cell methotrexate polyglutamate concentrations and disease activity
in patients with rheumatoid arthritis. Journal of Rheumatology, 38(12), 2540-2547. doi: 10.3899/jrheum.110481
Stamp, L. K., & Chapman, P. T. (2012). Gout and organ transplantation. Current Rheumatology Reports, 14(2), 165-172. doi:
10.1007/s11926-012-0235-9
Walker, J., Shadanbaz, S., Kirkland, N. T., Stace, E., Woodfield, T., Staiger, M. P., & Dias, G. J. (2012). Magnesium alloys:
Predicting in vivo corrosion with in vitro immersion testing. Journal of Biomedical Materials Research Part B, 100B(4),
1134-1141. doi: 10.1002/jbm.b.32680
Warren, C., Gilchrist, N., Coates, M., Frampton, C., Helmore, J., McKie, J., & Hooper, G. (2012). Atypical subtrochanteric
fractures, bisphosphonates, blinded radiological review. ANZ Journal of Surgery. Advance online publication. doi:
10.1111/j.1445-2197.2012.06199.x
Waterman, J., Birbilis, N., Dias, G. J., Woodfield, T. B. F., & Staiger, M. P. (2012). Improving in vitro corrosion resistance of
biomimetic calcium phosphate coatings for Mg substrates using calcium hydroxide layer. Corrosion Engineering, Science &
Technology, 47(5), 340-345. doi: 10.1179/1743278212y.0000000018
Waterman, J., Pietak, A., Birbilis, N., Woodfield, T., Dias, G., & Staiger, M. P. (2011). Corrosion resistance of biomimetic
calcium phosphate coatings on magnesium due to varying pretreatment time. Materials Science & Engineering: B, 176(20),
1756-1760. doi: 10.1016/j.mseb.2011.06.021
Journal - Research Other
Al-Mahrouqi, H., Munro, Z., Acland, R. H., & MacFarlane, M. R. (2012). Spinal cord stimulation for intractable chronic upper
abdominal pain: A case report of the first patient in New Zealand. New Zealand Medical Journal, 125(1367). Retrieved
from http://journal.nzma.org.nz/journal/125-1367/5477/content.pdf.
Beadel, G. (2012). Treating soft tissue sarcomas [Editorial]. New Zealand Medical Journal, 125(1366). Retrieved from http://
journal.nzma.org.nz/journal/125-1366/5444/content.pdf.
Derrett, S., Beaver, C., Sullivan, M. J., Herbison, G. P., Acland, R., & Paul, C. (2012). Traumatic and non-traumatic spinal
cord impairment in New Zealand: Incidence and characteristics of people admitted to spinal units [Brief report]. Injury
Prevention. Advance online publication. doi: 10.1136/injuryprev-2011-040266
Hooper, G. (2011). [Reply to letter to the editor Against anterior cruciate ligament reconstructions]. New Zealand Medical
Journal, 124(1334). Retrieved from http://journal.nzma.org.nz/journal/124-1334/4650/content.pdf.
Hooper, G. (2011). [Reply to letter to the editor Anterior cruciate ligament reconstructions, the debate continues: With another
response by Assoc Prof Hooper]. New Zealand Medical Journal, 124(1335). Retrieved from http://journal.nzma.org.nz/
journal/124-1335/4692/content.pdf.
Hooper, G. (2011). Sarcoma services in New Zealand [Editorial]. New Zealand Medical Journal, 124(1346). Retrieved from
http://journal.nzma.org.nz/journal/124-1346/4964/content.pdf.
Thompson, B. (2012). Are you ready? Readiness to return to work for people living with chronic pain. Occupational Therapy
Now, 14(5), 13-15.
Commissioned Report for External Body
Rothwell, A., Hobbs, T., & Frampton, C. (2012). The New Zealand Joint Registry: Thirteen year report: January 1999 to
December 2011. Commissioned by New Zealand Orthopaedic Association. 149p.
Awarded Doctoral Degree
Dunn, J. A. (2012). Getting a grip on it: People with tetraplegia making the decision about upper limb surgery (PhD). University
of Otago, Dunedin, New Zealand. 213p.
University of Otago, Christchurch
Paediatrics
Authored Book - Other
Pattemore, P. (2011). Am I my keeper’s brother? Human origins from a Christian and scientific perspective. Christchurch, New
Zealand: P. Pattemore, 416p.
Chapter in Book - Research
Bagshaw, S. (2011). Resiliency. In P. Gluckman & H. Hayne (Eds.), Improving the transition: Reducing social and psychological
morbidity during adolescence: A report from the Prime Minister’s Chief Science Advisor (pp. 79-86). Auckland, New Zealand:
Office of the Prime Minister’s Science Advisory Committee.
Bagshaw, S. (2011). Sexually healthy young people. In P. Gluckman & H. Hayne (Eds.), Improving the transition: Reducing
social and psychological morbidity during adolescence: A report from the Prime Minister’s Chief Science Advisor (pp. 133-144).
Auckland, New Zealand: Office of the Prime Minister’s Science Advisory Committee.
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Journal - Research Article
Alonso-González, L., Couldrey, C., Meinhardt, M. W., Cole, S. A., Wells, D. N., & Laible, G. (2012). Primary transgenic bovine
cells and their rejuvenated cloned equivalents show transgene-specific epigenetic differences. PLoS ONE, 7(4), e35619. doi:
10.1371/journal.pone.0035619
Andre, C. M., Greenwood, J. M., Walker, E. G., Rassam, M., Sullivan, M., Evers, D., Perry, N. B., Laing, W. A. (2012). Antiinflammatory procyanidins and triterpenes in 109 apple varieties. Journal of Agricultural & Food Chemistry, 60(42), 1054610554. doi: 10.1021/jf302809k
Askie, L. M., Brocklehurst, P., Darlow, B. A., Finer, N., Schmidt, B., Tarnow-Mordi, W., the NeOProM Collaborative Group.
(2011). NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol. BMC Pediatrics, 11, 6.
doi: 10.1186/1471-2431-11-6
Aurangzeb, B., Leach, S. T., Lemberg, D. A., & Day, A. S. (2011). Assessment of nutritional status and serum leptin in children
with inflammatory bowel disease. Journal of Pediatric Gastroenterology & Nutrition, 52(5), 536-541. doi: 10.1097/
MPG.0b013e3181f87a95
Aurangzeb, B., Whitten, K. E., Harrison, B., Mitchell, M., Kepreotes, H., Sidler, M., … Day, A. S. (2012). Prevalence of
malnutrition and risk of under-nutrition in hospitalized children. Clinical Nutrition, 31(1), 35-40. doi: 10.1016/j.
clnu.2011.08.011
Bandopadhayay, P., Hassall, T. E., Rosenfeld, J. V., Wheeler, G. C., Downie, P. A., Kirby, M. L., … Sullivan, M. J., Ashley, D. M.
(2011). ANZCCSG BabyBrain99; Intensified systemic chemotherapy, second look surgery and involved field radiation
in young children with central nervous system malignancy. Pediatric Blood & Cancer, 56(7), 1055-1061. doi: 10.1002/
pbc.22942
Baumgart, D. C., Bernstein, C. N., Abbas, Z., Colombel, J. F., Day, A. S., D’Haens, G., … Yamamoto- Furusho, J. K. (2011). IBD
around the world: Comparing the epidemiology, diagnosis, and treatment: Proceedings of the World Digestive Health Day
2010: Inflammatory bowel disease task force meeting. Inflammatory Bowel Diseases, 17(2), 639-644. doi: 10.1002/ibd.21409
Beasley, R. W., Clayton, T. O., Crane, J., Lai, C. K. W., Montefort, S. R., von Mutius, E., … and the ISAAC Phase Three Study
Group, including Pattemore, P. (2011). Acetaminophen use and risk of asthma, rhinoconjunctivitis and eczema in
adolescents: International Study of Asthma and Allergies in Childhood Phase Three. American Journal of Respiratory &
Critical Care Medicine, 183(2), 171-178. doi: 10.1164/rccm.201005-0757OC
Bentley, R. W., Keown, D. A., Gearry, R. B., Cameron, V. A., Keenan, J., Roberts, R. L., & Day, A. S. (2012). Vitamin D receptor
polymorphisms in colorectal cancer in New Zealand: An association study. New Zealand Medical Journal, 125(1356).
Retrieved from http://journal.nzma.org.nz/journal/125-1356/5212/content.pdf.
Björkstén, B., Aït-Khaled, N., Innes Asher, M., Clayton, T. O., Robertson, C., the ISAAC Phase Three Study Group,
including Beasley, R., Crane, J., Pattemore, P. (2011). Global analysis of breast feeding and risk of symptoms of asthma,
rhinoconjunctivitis and eczema in 6–7 year old children: ISAAC Phase Three. Allergologia et Immunopathologia, 39(6),
318-325. doi: 10.1016/j.aller.2011.02.005
Bora, S., Pritchard, V., Moor, S., Austin, N. C., & Woodward, L. J. (2011). Emotional and behavioural adjustment of
children born very preterm at early school age. Journal of Paediatrics & Child Health, 47, 863-869. doi: 10.1111/j.14401754.2011.02105.x
Brocklehurst, P., Farrell, B., King, A., Juszczak, E., Darlow, B. A., Haque, K., … on behalf of the INIS Trial Collaborative Group.
(2011). Treatment of neonatal sepsis with intravenous immune globulin. New England Journal of Medicine, 365(13), 12011211. doi: 10.1056/NEJMoa1100441
Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R., Silvers, K. M., Epton, M. J., Town, G. I., Pattemore, P. K., … Crane, J.,
the New Zealand Asthma and Allergy Cohort Study Group (NZAAACS6). (2011). Cord-blood 25-hydroxyvitamin D levels
and risk of respiratory infection, wheezing, and asthma. Pediatrics, 127(1), e180-e187. doi: 10.1542/peds.2010-0442
Crane, J., Lampshire, P., Wickens, K., Epton, M., Siebers, R., Ingham, T., Pattemore, P., Town, I., and the Year Six New Zealand
Asthma and Allergy Cohort Study Group, (NZAACS6). (2012). Asthma, atopy and exhaled nitric oxide in a cohort of 6-yrold New Zealand children. Pediatric Allergy & Immunology, 23(1), 59-64. doi: 10.1111/j.1399-3038.2011.01227.x
Critch, J., Day, A. S., Otley, A., King-Moore, C., Teitelbaum, J. E., & Shashidhar, H. (2012). Use of enteral nutrition for the
control of intestinal inflammation in pediatric Crohn disease. Journal of Pediatric Gastroenterology & Nutrition, 54(2), 298305. doi: 10.1097/MPG.0b013e318235b397
Darlow, B. A., Ells, A. L., Gilbert, C. E., Gole, G. A., & Quinn, G. E. (2011). Are we there yet? Bevacizumab therapy for
retinopathy of prematurity. Archives of Disease in Childhood: Fetal & Neonatal Edition. Advance online publication. doi:
10.1136/archdischild-2011-301148
Darlow, B. A., & Graham, P. J. (2011). Vitamin A supplementation to prevent mortality and short- and long-term morbidity
in very low birthweight infants (Review). Cochrane Database of Systematic Reviews, 10, CD000501. doi: 10.1002/14651858.
CD000501.pub3
Darlow, B. A., Phillips, A. A., & Dickson, N. P. (2011). New Zealand surveillance of neonatal vitamin K deficiency bleeding
(VKDB): 1998-2008. Journal of Paediatrics & Child Health, 47(7), 460-464. doi: 10.1111/j.1440-1754.2010.01995.x
Day, A. S., Judd, T., Lemberg, D. A., & Leach, S. T. (2012). Fecal M2-PK in children with Crohn’s disease: A preliminary report.
Digestive Diseases & Sciences. Advance online publication. doi: 10.1007/s10620-012-2215-3
Day, A. S., & Keenan, J. (2011). Probiotic-mediated modulation of host inflammation. Expert Review of Gastroenterology &
Hepatology, 5(3), 319-321. doi: 10.1586/egh.11.34
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Day, A. S., Ledder, O., Leach, S. T., & Lemberg, D. A. (2012). Crohn’s and colitis in children and adolescents. World Journal of
Gastroenterology, 18(41), 5862-5869. doi: 10.3748/wjg.v18.i41.5862
Denny, S., Robinson, E., Lawler, C., Bagshaw, S., Farrant, B., Bellamy, F., … Utter, J. (2012). Association between availability
and quality of health services in schools and reproductive health outcomes among students: A multilevel observational
study. American Journal of Public Health. Advance online publication. doi: 10.2105/ajph.2012.300775
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., Bentley, R. W. (2011). NOD2
and ATG16L1 polymorphisms affect monocyte responses in Crohn’s disease. World Journal of Gastroenterology, 17(23),
2829-2837. doi: 10.3748/wjg.v17.i23.2829
Harwood, D. T., Darlow, B. A., Cheah, F. C., McNeill, N., Graham, P., & Winterbourn, C. C. (2011). Biomarkers of neutrophilmediated glutathione and protein oxidation in tracheal aspirates from preterm infants: Association with bacterial
infection. Pediatric Research, 69(1), 28-33. doi: 10.1203/PDR.0b013e3181ff2378
Huang, B., Li, T., Alonso-Gonzalez, L., Gorre, R., Keatley, S., Green, A., … Oback, B. (2011). A virus-free poly-promoter vector
induces pluripotency in quiescent bovine cells under chemically defined conditions of dual kinase inhibition. PLoS ONE,
6(9), e24501. doi: 10.1371/journal.pone.0024501
Ismail, Y., Mahendran, V., Octavia, S., Day, A. S., Riordan, S. M., Grimm, M. C., … Zhang, L. (2012). Investigation of the
enteric pathogenic potential of oral Campylobacter concisus strains isolated from patients with inflammatory bowel
disease. PLoS ONE, 7(5), e38217. doi: 10.1371/journal.pone.0038217
Jacobs, S. E., Morley, C. J., Inder, T. E., Stewart, M. J., Smith, K. R., McNamara, P. J., … Darlow, B. A., … for the Infant Cooling
Evaluation Collaboration. (2011). Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic
encephalopathy: A randomized controlled trial. Archives of Pediatrics & Adolescent Medicine, 165(8), 692-700. doi: 10.1001/
archpediatrics.2011.43
Judd, T. A., Day, A. S., Lemberg, D. A., Turner, D., & Leach, S. T. (2011). Update of fecal markers of inflammation in
inflammatory bowel disease. Journal of Gastroenterology & Hepatology, 26(10), 1493-1499. doi: 10.1111/j.14401746.2011.06846.x
Kaakoush, N. O., Day, A. S., Huinao, K. D., Leach, S. T., Lemberg, D. A., …, & Mitchell, H. M. (2012). Microbial dysbiosis in
pediatric patients with Crohn’s disease. Journal of Clinical Microbiology, 50(10), 3258-3266. doi: 10.1128/jcm.01396-12
Kaakoush, N. O., Deshpande, N. P., Wilkins, M. R., Tan, C. G., Burgos-Portugal, J. A., Raftery, M. J., Day, A. S., … Mitchell, H.
(2011). The pathogenic potential of Campylobacter concisus strains associated with chronic intestinal diseases. PLoS ONE,
6(12), e29045. doi: 10.1371/journal.pone.0029045
Lambert, B., Lemberg, D. A., Leach, S. T., & Day, A. S. (2012). Longer-term outcomes of nutritional management of Crohn’s
disease in children. Digestive Diseases & Sciences, 57(8), 2171-2177. doi: 10.1007/s10620-012-2232-2
Le Compte, A. J., Chase, J. G., Lynn, A., Hann, C. E., Shaw, G. M., & Lin, J. (2011). Development of blood glucose control
for extremely premature infants. Computer Methods & Programs in Biomedicine, 102(2), 181-191. doi: 10.1016/j.
cmpb.2010.03.010
Le Compte, A. J., Lynn, A. M., Lin, J., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2012). Pilot study of a model-based approach
to blood glucose control in very-low-birthweight neonates. BMC Pediatrics, 12, 117. doi: 10.1186/1471-2431-12-117
Lee, J. M., Leach, S. T., Katz, T., Day, A. S., Jaffe, A., & Ooi, C. Y. (2012). Update of faecal markers of inflammation in children
with cystic fibrosis. Mediators of Inflammation, 2012, 948367. doi: 10.1155/2012/948367
Lee, D. S., Zahari, M., Russell, G., Darlow, B. A., Scarrott, C. J., & Reale, M. (2011). An exploratory investigation of some
statistical summaries of oximeter oxygen saturation data from preterm babies. ISRN Pediatrics, 2011, 296418. doi:
10.5402/2011/296418
Levin, A. D., Wadhera, V., Leach, S. T., Woodhead, H. J., Lemberg, D. A., Mendoza-Cruz, A. C., & Day, A. S. (2011). Vitamin D
deficiency in children with inflammatory bowel disease. Digestive Diseases & Sciences, 56(3), 830-836. doi: 10.1007/s10620010-1544-3
Li-Kim-Moy, J. P., Tobias, V., Day, A. S., Leach, S., & Lemberg, D. A. (2011). Esophageal subepithelial fibrosis and hyalinization
are features of eosinophilic esophagitis. Journal of Pediatric Gastroenterology & Nutrition, 52(2), 147-153. doi: 10.1097/
MPG.0b013e3181ef37a1
Lion, M., Gearry, R. B., Day, A. S., & Eglinton, T. W. (2012). The cost of paediatric and perianal Crohn’s disease in
Canterbury, New Zealand. New Zealand Medical Journal, 125(1349). Retrieved from http://journal.nzma.org.nz/
journal/125-1349/5055/content.pdf.
Lopez, R., Beasley, S. W., Blakelock, R., Maoate, K., McBride, C. A., Slade, C., Day, A. S., King, S. K. (2012). The role of steroids
in children with multiple recurrences of intussusception. Journal of Paediatrics & Child Health, 48(2), 180-181. doi:
10.1111/j.1440-1754.2011.02406.x
Loughran-Fowlds, A., Leach, S., Lin, J., Oei, J., Henry, R., Day, A. S., & Lui, K. (2011). Respiratory disease and early serum
S100A12 changes in very premature infants. Acta Paediatrica, 20, 1538-1543. doi: 10.1111/j.1651-2227.2011.02384.x
MacDonald, A., Scarrott, C. J., Lee, D., Darlow, B., Reale, M., & Russell, G. (2011). A flexible extreme value mixture model.
Computational Statistics & Data Analysis, 55(6), 2137-2157. doi: 10.1016/j.csda.2011.01.005
Mangin, D., Murdoch, D., Wells, J. E., Coughlan, E., Bagshaw, S., Corwin, P., Chambers, S., Toop, L. (2011). Chlamydia
trachomatis testing sensitivity in midstream compared with first-void urine specimens. Annals of Family Medicine, 10(1),
50-53. doi: 10.1370/afm.1323
Martin, A. J., Darlow, B. A., Salt, A., Hague, W., Sebastian, L., Mann, K., … on behalf of the INIS Trial Collaborative Group.
(2012). Identification of infants with major cognitive delay using parental report. Developmental Medicine & Child
Neurology, 54(3), 254-259. doi: 10.1111/j.1469-8749.2011.04161.x
236
RESEARCH REPORT 2011/2012
Meijer, B., Gearry, R. B., & Day, A. S. (2012). The role of S100A12 as a systemic marker of inflammation. International Journal
of Inflammation, 2012, 907078. doi: 10.1155/2012/907078
Miller, L. J., Willis, J. A., Pearce, J., Barnett, R., Darlow, B. A., & Scott, R. S. (2011). Urban-rural variation in childhood
type 1 diabetes incidence in Canterbury, New Zealand, 1980 to 2004. Health & Place, 17(1), 248-256. doi: 10.1016/j.
healthplace.2010.10.010
Moeeni, V., Walls, T., & Day, A. S. (2012). Assessment of nutritional status and nutritional risk in hospitalised Iranian children.
Acta Paediatrica, 101(10), e446-e451. doi: 10.1111/j.1651-2227.2012.02789.x
Moyes, C. D., Clayton, T., Pearce, N., Asher, M. I., Ellwood, P., MacKay, R., … Pattemore, P., … Crane, J. (2012). Time trends
and risk factors for rhinoconjunctivitis in New Zealand children: An International Study of Asthma and Allergies in
Childhood (ISAAC) survey. Journal of Paediatrics & Child Health. Advance online publication. doi: 10.1111/j.14401754.2012.02518.x
Nahidi, L., Day, A. S., Lemberg, D. A., & Leach, S. T. (2012). Differential effects of nutritional and non-nutritional therapies on
intestinal barrier function in an in vitro model. Journal of Gastroenterology, 47(2), 107-117. doi: 10.1007/s00535-011-0471-1
Nahidi, L., Leach, S. T., Sidler, M. A., Levin, A., Lemberg, D. A., & Day, A. S. (2011). Osteoprotegerin in pediatric Crohn’s
disease and the effects of exclusive enteral nutrition. Inflammatory Bowel Diseases, 17(2), 516-523. doi: 10.1002/ibd.21361
Prickett, T. C. R., Lyver, A., Wilson, R., Espiner, E. A., & Sullivan, M. J. (2012). C-type natriuretic peptide: A novel biomarker of
steroid induced bone toxicity in children with acute lymphoblastic leukemia (ALL). Peptides, 36(1), 54-59. doi: 10.1016/j.
peptides.2012.04.017
Purcell, R., Childs, M., Maibach, R., Miles, C., Turner, C., Zimmermann, A., … Sullivan, M. (2012). Potential biomarkers
for hepatoblastoma: Results from the SIOPEL-3 study. European Journal of Cancer, 48(12), 1853-1859. doi: 10.1016/j.
ejca.2011.10.019
Purcell, R., Childs, M., Maibach, R., Miles, C., Turner, C., Zimmermann, A., & Sullivan, M. (2011). HGF/c-Met related
activation of β-catenin in hepatoblastoma. Journal of Experimental & Clinical Cancer Research, 30, 96. doi: 10.1186/17569966-30-96
Ramsden, L., & Day, A. S. (2012). Paediatric growth charts: How do we use them and can we use them better? Journal of
Paediatrics & Child Health, 48(1), 22-25. doi: 10.1111/j.1440-1754.2011.02185.x
Silvers, K. M., Frampton, C. M., Wickens, K., Pattemore, P. K., Ingham, T., Fishwick, D., Crane, J., Town, G. I., Epton, M. J.,
on behalf of the New Zealand Asthma and Allergy Cohort Study Group. (2012). Breastfeeding protects against current
asthma up to 6 years of age. Journal of Pediatrics, 160(6), 991-996. doi: 10.1016/j.jpeds.2011.11.055
Stewart, M., Day, A. S., & Otley, A. (2011). Physician attitudes and practices of enteral nutrition as primary treatment of
paediatric Crohn disease in North America. Journal of Pediatric Gastroenterology & Nutrition, 52(1), 38-42. doi: 10.1097/
MPG.0b013e3181e2c724
Tanpowpong, P., Ingham, T. R., Lampshire, P. K., Kirchberg, F. F., Epton, M. J., Crane, J., … and the New Zealand Asthma and
Allergy Cohort Study Group, including Pattemore, P., Siebers, R., Wickens, K. (2012). Coeliac disease and gluten avoidance
in New Zealand children. Archives of Disease in Childhood, 97, 12-16. doi: 10.1136/archdischild-2011-300248
Tilakaratne, S., Day, A., & Lemberg, D. (2012). Eosinophilic esophagitis and food impaction: An instructive case. Turkish
Journal of Gastroenterology, 23(3), 294-297. doi: 10.4318/tjg.2012.0386
van de Logt, F., & Day, A. S. (2012). S100A12: A noninvasive marker of inflammation in inflammatory bowel disease. Journal of
Digestive Diseases. Advance online publication. doi: 10.1111/1751-2980.12012
Vella-Brincat, J. W. A., Begg, E. J., Robertshawe, B. J., Lynn, A. M., Borrie, T. L., & Darlow, B. A. (2011). Are gentamicin
and/or vancomycin associated with ototoxicity in the neonate? A retrospective audit. Neonatology, 100, 186-193. doi:
10.1159/000324857
Wadhera, V., Lemberg, D. A., Leach, S. T., & Day, A. S. (2011). Complementary and alternative medicine in children attending
gastroenterology clinics: Usage patterns and reasons for use. Journal of Paediatrics & Child Health, 47(12), 904-910. doi:
10.1111/j.1440-1754.2011.02100.x
Wickens, K., Beasley, R., Town, G. I., Epton, M., Pattemore, P., Ingham, T., Crane, J., and the New Zealand Asthma and Allergy
Cohort Study Group. (2011). The effects of early and late paracetamol exposure on asthma and atopy: A birth cohort.
Clinical & Experimental Allergy, 41(3), 399-406. doi: 10.1111/j.1365-2222.2010.03610.x
Journal - Research Other
Day, A. S., & Lemberg, D. A. (2011). Reduced sepsis with enteral antibiotics in children with intestinal failure [Invited
commentary]. Alimentary Pharmacology & Therapeutics, 34(10), 1247-1248. doi: 10.1111/j.1365-2036.2011.04858.x
Day, A. S., Mitchell, H. M., Leach, S. T., & Lemberg, D. A. (2012). Comment to: Changes of faecal microflora in patients with
Crohn’s disease treated with an elemental diet and total parenteral nutrition [Letter to the editor]. Digestive & Liver
Disease. Advance online publication. doi: 10.1016/j.dld.2012.07.014
Gilbert, C. E., Zin, A., & Darlow, B. (2011). Bevacizumab for retinopathy of prematurity [Letter to the editor]. New England
Journal of Medicine, 364(24), 2359-2360.
Hudson, B., Alderton, A., Doocey, C., Nicholson, D., Toop, L., & Day, A. S. (2012). Crying and spilling: Time to stop the
overmedicalisation of normal infant behaviour [Viewpoint]. New Zealand Medical Journal, 125(1367). Retrieved from
http://journal.nzma.org.nz/journal/125-1367/5475/content.pdf.
Keenan, J. I., Mitchell, H. M., & Day, A. S. (2011). Interactions between gastric and enteric infections: Clues to the pathogenesis
of inflammatory bowel disease? [Viewpoint]. New Zealand Medical Journal, 124(1332). Retrieved from http://journal.
nzma.org.nz/journal/124-1332/4606/content.pdf.
237
RESEARCH REPORT 2011/2012
Lambert, B., Lemberg, D. A., Leach, S. T., & Day, A. S. (2012). [Reply to the letter Long-term efficacy of enteral nutrition for
patients with Crohn’s disease]. Digestive Diseases & Sciences, 57(12), 3311.
Lopez, R., King, S., Maoate, K., & Beasley, S. (2011). Laparoscopic repair of paediatric traumatic Spigelian hernia avoids the
need for mesh [Letter to the editor]. ANZ Journal of Surgery, 81(5), 396-397. doi: 10.1111/j.1445-2197.2011.05720.x
McMullan, B., Dabscheck, G., Robertson, P., Johnston, H., Rawlinson, W., & Walls, T. (2011). Pandemic (H1N1) 2009 influenza
with neurological complications diagnosed using specific serology with the haemagglutinin inhibition assay [Letter].
Pathology, 43(5), 512-513. doi: 10.1097/PAT.0b013e3283486b46
Meijer, B., Gearry, R. B., & Day, A. S. (2012). S100A12 in EDTA plasma: A cautionary tale [Letter to the editor]. Journal of
Crohn’s & Colitis, (0). Advance online publication. doi: 10.1016/j.crohns.2012.05.020
Moeeni, V., & Day, A. S. (2011). Impact of inflammatory bowel disease upon growth in children and adolescents. ISRN
Pediatrics, 2011, 365712. doi: 10.5402/2011/365712
Tarnow-Mordi, W. O., Evans, N. J., Lui, K., Darlow, B., on behalf of the Advisory Committee of the Australian and New
Zealand Neonatal Network. (2011). Risk of brain damage in babies from naphthalene in mothballs: Call to consider a
national ban [Letter to the editor]. Medical Journal of Australia, 194(3), 150.
Walls, T., Best, E., Murdoch, D., & Mills, N. (2011). Vaccination to prevent otitis media in New Zealand [Editorial]. New
Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.nz/journal/124-1340/4807/content.pdf.
Walls, T., Williams, G., Adams, S., Sugo, E., & Mulcahy, D. (2011). Neonatal necrotising fasciitis following superficial skin
infection with community-associated methicillin-resistant Staphylococcus aureus [Case report]. Journal of Paediatrics &
Child Health, 47(12), 918-920. doi: 10.1111/j.1440-1754.2010.01732.x
Journal - Professional & Other Non-Research Articles
Bentley, R. W., Keown, D., Merriman, T. R., Krishnan, M. R., Gearry, R. B., Barclay, M. L., Roberts, R. L., Day, A. S. (2011).
Vitamin D receptor gene polymorphism associated with inflammatory bowel disease in New Zealand males [Letter to the
editor]. Alimentary Pharmacology & Therapeutics, 33(7), 855-856. doi: 10.1111/j.1365-2036.2011.04588.x
Day, A. S., & Aird, C. (2011). [Review of the book Examination paediatrics: A guide to paediatric training (4th ed)]. New
Zealand Medical Journal, 124(1347). Retrieved from http://journal.nzma.org.nz/journal/124-1347/4998/content.pdf.
University of Otago, Christchurch
Pathology
Chapter in Book - Research
Morris, C. M. (2011). Chronic myeloid leukemia: Cytogenetic methods and applications for diagnosis and treatment. In L. J.
Campbell (Ed.), Cancer cytogenetics: Methods and protocols: Methods in molecular biology (Vol. 730) (2nd ed.) (pp. 33-61).
New York: Springer. doi: 10.1007/978-1-61779-074-4_4
Svistunenko, D., Zykova, S. N., Cogger, V. C., Warren, A., Fraser, R., Smedsrød, B., … Le Couteur, D. G. (2011).
Pseudocapillarization and the aging liver. In L. D. DeLeve & G. Garcia-Tsao (Eds.), Vascular liver disease: Mechanisms and
management (pp. 41-50). New York: Springer. doi: 10.1007/978-1-4419-8327-5_3
Winterbourn, C. C. (2012). Biological chemistry of reactive oxygen species. In C. Chatgilialoglu & A. Studer
(Eds.), Encyclopedia of radicals in chemistry, biology and materials (pp. 1259-1281). Chichester, UK: Wiley. doi:
10.1002/9781119953678.rad077
Journal - Research Article
Members of the Western Pacific Region Global Influenza Surveillance and Response System, including Jennings, L.
(2012). Epidemiological and virological characteristics of influenza in the Western Pacific Region of the World Health
Organization: 2006-2010. PLoS ONE, 7(5), e37568. doi: 10.1371/journal.pone.0037568
Aldous, S. J., Florkowski, C. M., Crozier, I. G., Elliott, J., George, P., Lainchbury, J. G., MacKay, R. J., Than, M. (2011).
Comparison of high sensitivity and contemporary troponin assays for the early detection of acute myocardial infarction in
the emergency department. Annals of Clinical Biochemistry, 48, 241-248. doi: 10.1258/acb.2010.010219
Andersen, J. T., Dalhus, B., Cameron, J., Daba, M. B., Plumridge, A., Evans, L., Brennan, S. O., … Sandlie, I. (2012). Structurebased mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. Nature Communications, 3, 610. doi:
10.1038/ncomms1607
Ang, S.-F., Moochhala, S. M., MacAry, P. A., & Bhatia, M. (2011). Hydrogen sulfide and neurogenic inflammation in
polymicrobial sepsis: Involvement of substance P and ERK-NF-κB signaling. PLoS ONE, 6(9), e24535. doi: 10.1371/
journal.pone.0024535
Ang, S.-F., Sio, S. W. S., Moochhala, S. M., MacAry, P. A., & Bhatia, M. (2011). Hydrogen sulfide upregulates cyclooxygenase-2
and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel
activation. Journal of Immunology, 187(9), 4778-4787. doi: 10.4049/jimmunol.1101559
Bhandari, S., Chambers, S., Pearson, J., Syhre, M., Epton, M., & Scott-Thomas, A. (2011). Determining the limits and
confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry. Journal of Chromatography B,
879(26), 2815-2820. doi: 10.1016/j.jchromb.2011.08.010
Bhat, N., O’Brien, K. L., Karron, R. A., Driscoll, A. J., Murdoch, D. R., and the Pneumonia Methods Working Group. (2012).
Use and evaluation of molecular diagnostics for pneumonia etiology studies. Clinical Infectious Diseases, 54(Suppl. 2),
S153-S158. doi: 10.1093/cid/cir1060
238
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Bhatia, M., Zemans, R. L., & Jeyaseelan, S. (2012). Role of chemokines in the pathogenesis of acute lung injury. American
Journal of Respiratory Cell & Molecular Biology, 46(5), 566-572. doi: 10.1165/rcmb.2011-0392TR
Braatvedt, G. D., Cundy, T., Crooke, M., Florkowski, C., Mann, J. I., Lunt, H., … Drury, P. L. (2012). Understanding the new
HbA1c units for the diagnosis of Type 2 diabetes [Review article]. New Zealand Medical Journal, 125(1362). Retrieved from
http://journal.nzma.org.nz/journal/125-1362/5345/content.pdf.
Brennan, S. O., Chan, T., & Duncan, J. (2012). Novel α2 gene deletion (c.349_359 del GAGTTCACCCC) identified in
association with the -α3.7 deletion. Hemoglobin, 36(1), 93-97. doi: 10.3109/03630269.2011.637592
Brennan, S. O., King, R. I., & Florkowski, C. M. (2012). β37Trp→Cys mutation leads to multiple new hemoglobin species in
red cells. Clinical Biochemistry, 45, 259-263. doi: 10.1016/j.clinbiochem.2011.12.001
Brennan, S. O., Pullon, B., Owen, M. C., & Brittain, T. (2012). Novel hemoglobin mutation (α127Lys→Glu) increases oxygen
affinity and has a minor effect on haptoglobin binding. Clinical Biochemistry. Advance online publication. doi: 10.1016/j.
clinbiochem.2012.08.021
Brown, K. K., & Hampton, M. B. (2011). Biological targets of isothiocyanates. Biochimica et Biophysica Acta: General Subjects,
1810(9), 888-894. doi: 10.1016/j.bbagen.2011.06.004
Carr, A. C., Pullar, J. M., Moran, S., & Vissers, M. C. M. (2012). Bioavailability of vitamin C from kiwifruit in non-smoking
males: determination of ‘healthy’ and ‘optimal’ intakes. Journal of Nutritional Science, 1, e14. doi: 10.1017/jns.2012.15
Chambers, S. T., Bhandari, S., Scott-Thomas, A., & Syhre, M. (2011). Novel diagnostics: Progress toward a breath test for
invasive Aspergillus fumigatus. Medical Mycology, 49(Suppl. 1), S54-S61. doi: 10.3109/13693786.2010.508187
Chambers, S. T., Scott-Thomas, A., & Epton, M. (2012). Developments in novel breath tests for bacterial and fungal
pulmonary infection. Current Opinion in Pulmonary Medicine, 18(3), 228-232. doi: 10.1097/MCP.0b013e328351f98b
Cheah, C. Y., Brennan, S. O., Kennedy, H., Januszewicz, E. H., Maxwell, E., & Burbury, K. (2012). Fibrinogen Melbourne:
A novel congenital hypodysfibrinogenemia caused by [gamma]326Cys-Phe in the fibrinogen [gamma] chain,
presenting as massive splanchnic venous thrombosis. Blood Coagulation & Fibrinolysis, 23(6), 563-565. doi: 10.1097/
MBC.0b013e328354a23b
Chew-Harris, J. S. C., Florkowski, C. M., George, P. M., Elmslie, J. L., & Endre, Z. H. (2012). The relative effects of fat versus
muscle mass on cystatin C and estimates of renal function in healthy young men. Annals of Clinical Biochemistry. Advance
online publication. doi: 10.1258/acb.2012.011241
Christiaans, I., Kenter, S. B., Brink, H. C., …, Kidd, A. M. J., & Hulsebos, T. J. M. (2011). Germline SMARCB1 mutation
and somatic NF2 mutations in familial multiple meningiomas. Journal of Medical Genetics, 48(2), 93-97. doi: 10.1136/
jmg.2010.082420
Chua, E. W., & Kennedy, M. A. (2012). Current state and future prospects of direct-to-consumer pharmacogenetics. Frontiers
in Pharmacology, 3, 152. doi: 10.3389/fphar.2012.00152
Cornelius, A. J., Chambers, S. T., Aitken, J., Brandt, S. M., Horn, B., & On, S. L. W. (2012). Epsilonproteobacteria in humans:
New Zealand. Emerging Infectious Diseases, 18(3), 510-512. doi: 10.3201/eid1803.110875
Cuddihy, S. L., Winterbourn, C. C., & Hampton, M. B. (2011). Assessment of redox changes to hydrogen peroxide-sensitive
proteins during EGF signaling. Antioxidants & Redox Signaling, 15(1), 167-174. doi: 10.1089/ars.2010.3843
Cui, X., Lu, Z., Kurosawa, A., Klemm, L., Bagshaw, A., Tsai, A. G., Gemmell, N., … Lieber, M. R. (2012). Both CpG methylation
and AID are required for the fragility of the human Bcl-2 major breakpoint region: Implications for the timing of the
breaks in the t(14;18). Molecular & Cellular Biology. Advance online publication. doi: 10.1128/MCB.01436-12
Currie, M. J., Beardsley, B. E., Harris, G. C., Gunningham, S. P., Dachs, G. U., Dijkstra, B., Morrin, H. R., Wells, J. E., Robinson,
B. A. (2012). Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal
carcinoma in situ: Relationships with markers of tumor hypoxia and microvascularity. Human Pathology. Advance online
publication. doi: 10.1016/j.humpath.2012.06.004
Davey, V., Robinson, B., Dijkstra, B., & Harris, G. (2012). The Christchurch Breast Cancer Patient Register: The first year. New
Zealand Medical Journal, 125(1360). Retrieved from http://journal.nzma.org.nz/journal/125-1360/5301/content.pdf.
DeLuca, A. N., Regenberg, A., Sugarman, J., Murdoch, D. R., & Levine, O. (2012). Bioethical considerations in developing a
biorepository for the Pneumonia Etiology Research for Child Health project. Clinical Infectious Diseases, 54(Suppl. 2),
S172-S179. doi: 10.1093/cid/cir1063
Driscoll, A. J., Bhat, N., Karron, R. A., O’Brien, K. L., & Murdoch, D. R. (2012). Disk diffusion bioassays for the detection of
antibiotic activity in body fluids: Applications for the Pneumonia Etiology Research for Child Health project. Clinical
Infectious Diseases, 54(Suppl. 2), S159-S164. doi: 10.1093/cid/cir1061
Dummer, J., Storer, M., Swanney, M., McEwan, M., Scott-Thomas, A., Bhandari, S., Chambers, S., … Epton, M. (2011).
Analysis of biogenic volatile organic compounds in human health and disease. Trends in Analytical Chemistry, 30(7), 960967. doi: 10.1016/j.trac.2011.03.011
Ellis, E., Chin, P. K. L., Hunt, P. J., Lunt, H., Lewis, J. G., & Soule, S. G. (2012). Is late-night salivary cortisol a better screening
test for possible cortisol excess than standard screening tests in obese patients with Type 2 diabetes? New Zealand Medical
Journal, 125(1353). Retrieved from http://journal.nzma.org.nz/journal/125-1353/5151/content.pdf.
Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M.,
Henderson, S. J., Nejat, M., Schollum, J. B. W., George, P. M. (2011). Improved performance of urinary biomarkers of acute
kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79,
1119-1130. doi: 10.1038/ki.2010.555
239
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Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin
interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic
Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429
Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A., & Kennedy, M. A. (2012). Moderating role of the MAOA genotype in
antisocial behaviour. British Journal of Psychiatry, 200(2), 116-123. doi: 10.1192/bjp.bp.111.093328
Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). MAOA, abuse exposure and antisocial
behaviour: 30-year longitudinal study. British Journal of Psychiatry, 198, 457-463. doi: 10.1192/bjp.bp.110.086991
Fergusson, D. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). Life stress, 5-HTTLPR and mental disorder: Findings
from a 30-year longitudinal study. British Journal of Psychi