BLOOD What is it? Blood is the red fluid that circulates in our blood vessels, i.e. veins and arteries. The main function of blood is to act as the body’s transport system, but it also has a major role in the body’s defense against infection. Blood is a constantly circulating fluid providing the body with nutrition, oxygen, and waste removal. Blood is mostly liquid, with numerous cells and proteins suspended in it, making blood "thicker" than pure water. The average person has about 5 liters (more than a gallon) of blood. Blood has many different functions, including: 1. transporting oxygen and nutrients to the lungs and tissues 2. forming blood clots to prevent excess blood loss 3. carrying cells and antibodies that fight infection 4. bringing waste products to the kidneys and liver, which filter and clean the blood 5. regulating body temperature White Cell Red cell Platelet Components? It has four main components: 1. 2. 3. 4. plasma, red blood cells, white blood cells, and platelets. Blood cells are produced in bone marrow (μυελόσ/ μεδοφλι) Plasma • Plasma The liquid component of blood is called plasma, a mixture of water, sugar, fat, protein, and salts. The main job of the plasma is to transport blood cells throughout your body along with nutrients, waste products, antibodies, clotting proteins, chemical messengers such as hormones, and proteins that help maintain the body's fluid balance. Plasma carries blood cells. Red Blood Cells (RBCs) (also called erythrocytes) Known for their bright red color, red cells are the most abundant (άφκονοσ) cell in the blood, accounting for about 40-45 percent of its volume. The shape of a red blood cell looks like a donut. Red blood cells start in the bone marrow and after approximately seven days of maturation are released into the bloodstream. Red blood cells have no nucleus and can easily change shape, helping them fit through the various blood vessels in your body. However, while the lack of a nucleus makes a red blood cell more flexible, it also limits the life of the cell as it travels through the smallest blood vessels, damaging the cell's membranes. The red blood cell survives on average Red cells carry oxygen only 120 days. White Blood Cells (leukocytes) White Blood Cells (also called leukocytes) White blood cells protect the body from infection. They are much fewer in number than red blood cells. They make antibodies, which are proteins that specifically target bacteria, viruses, and other foreign materials. Platelets (αιμοπετάλια) Platelets (also called thrombocytes) Platelets are not actually cells but rather small colorless cell fragments in the blood whose main function is to interact with clotting proteins to stop or prevent bleeding. • A higher than normal number of platelets (thrombocytosis -θρομβοκυττάρωση) can cause unnecessary clotting, which can lead to strokes and heart attacks; • lower than normal number of platelets (thrombocytopenia -θρομβοπενία) can lead to extensive bleeding. Blood clots (θρόμβοι) Blood must flow continuously and smoothly throughout your body for an entire lifetime, but quickly shut off (αποςυνδζω, διακόπτω παροχι) to prevent spills when you get a cut or injury. Blood clots are healthy and lifesaving when they stop bleeding. But when they aren't needed they cause a heart attack, stroke, or other serious medical problems. What Causes Blood Clots? The process begins whenever flowing blood comes into contact with specific substances in your skin or in blood vessel walls. When they touch, it usually means the skin or blood vessel wall is broken. Cholesterol plaques that form in arteries have these things inside, too. If the plaque breaks open, they'll start the clotting process. Most heart attacks and strokes happen when a plaque in your heart or brain suddenly bursts. Blood clots can also form when your blood doesn't flow properly. If it pools in your blood vessels or heart, the platelets are more likely to stick together. Slowly moving blood can cause clotting problems. Blood type (Blood groups) A classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells. These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system. The Rhesus (Rh) system • Rh system (ςφςτθμα ταξινόμθςθσ αίματοσ) Ρζηουσ The Rh system classifies blood as Rhpositive or Rh-negative, based on the presence or absence of Rh antibodies in the blood. People with Rh-positive blood can receive Rh-negative blood, but people with Rh-negative blood will have a transfusion reaction if they receive Rhpositive blood. Transfusion reactions caused by mismatched Rh blood types can be serious. Blood types/ Donors recipients • Our blood is typed, or classified, according to the presence or absence of certain markers (antigens-αντιγόνα) found on red blood cells and in the plasma that allow your body to recognize blood as its own. If another blood type is introduced, your immune system recognizes it as foreign and attacks it, resulting in a transfusion reaction. i.e. People with type A have antibodies in the blood against type B. O = It is the universal donor Blood cells Blood types/ Donors recipients plasma Whole Blood (red cells, white cells, and platelets suspended in plasma) Bibliography http://www.redcrossblood.org http://kidshealth.org http://www.americasblood.org https://my.blood.co.uk/ http://www.webmd.com http://study.com/academy https://en.wikipedia.org
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