Karyotyping Web Activity
Objective: Complete the web activity to practice completing and analyzing karyotypes.
Procedures:
1. Go to this website: http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html
2. Follow the tabs at the bottom of each page to complete the steps for each of the three patients, and
follow this paper as a guide and remember to read both this paper and the website carefully.
3. For EACH patient, do the following:
a. Patient A:
Read Patient A’s history, and record the following:
i. What or who is the patient?
ii. Where or how were the chromosomes retrieved?
iii. Click on “Complete Patient A’s Karyotype”, and complete the karyotype following the prompts.
iv. When you have completed the karyotype, follow the instructions to interpret the karyotype. Write down
the notation for Patient A’s karyotype. (It should be a number—the total number of chromosomes and
then XX or XY to show male or female…for example, a normal female would be 46XX.)
v. Using the table, write down your diagnosis for Patient A (What disorder to they have?) and why you
give this diagnosis.
vi. Click to go to Patient B.
b. Patient B:
Read Patient B’s history, and record the following:
i. What or who is the patient?
ii. Where or how were the chromosomes retrieved?
iii. Click on “Complete Patient B’s Karyotype”, and complete the karyotype following the prompts.
iv. When you have completed the karyotype, follow the instructions to interpret the karyotype. Write down
the notation for Patient B’s karyotype.
v. Using the table, write down your diagnosis for Patient B (What disorder to they have?) and why do you
think that.
vi. Click to go to Patient C
c. Patient C
Read Patient C’s history, and record the following:
i. What or who is the patient?
ii. Where or how were the chromosomes retrieved?
iii. Click on “Complete Patient C’s Karyotype”, and complete the karyotype following the prompts.
iv. When you have completed the karyotype, follow the instructions to interpret the karyotype. Write down
the notation for Patient C’s karyotype.
v. Using the table, write down your diagnosis for Patient C (What disorder to they have?) and why do you
say that.