GLOBAL NUCLEAR MEDICINE (MEDICAL ISOTOPES/RADIOISOTOPES/ RADIOPHARMACEUTICALS) MARKET IN PET/SPECT IMAGING & THERAPY Competitive Landscape, Current Trends & Forecasts (2010 – 2015) MarketsandMarkets [email protected] www.marketsandmarkets.com Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts MarketsandMarkets is a global market research and consulting company based in the U.S. We publish strategically analyzed market research reports and serve as a business intelligence partner to Fortune 500 companies across the world. MarketsandMarkets also provides multi-client reports, company profiles, databases, and custom research services. 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MarketsandMarkets 2 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts TABLE OF CONTENTS EXECUTIVE SUMMARY .................................................................................................5 MARKET SCENARIO..................................................................... 5 1 SUMMARY..................................................................................................................7 2 MARKET OVERVIEW ..............................................................................................8 2.1 MARKET SEGMENTATION ............................................................ 8 3 RADIOPHARMACEUTICAL MARKET, BY ISOTOPES .................................. 10 3.1 LACK OF AVAILABILITY OF TECHNETIUM ................................. 10 4 RADIOPHARMACEUTICAL MARKET, BY ROUTES OF ADMINISTRATION (ROA) .................................................................................. 12 5 RADIOPHARMACEUTICAL MARKET, BY APPLICATIONS ........................ 13 6 GEOGRAPHIC ANALYSIS (CONSUMPTION) .................................................. 14 6.1 JAPAN....................................................................................... 14 MarketsandMarkets 3 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts LIST OF TABLES TABLE 1 RADIOPHARMACEUTICAL MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) 7 TABLE 2 TECHNETIUM MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($THOUSAND) 10 TABLE 3 NORTH AMERICA: THALLIUM MARKET REVENUE, BY COUNTRIES, 2008 – 2015 ($THOUSAND) 11 TABLE 4 INHALATION ROUTE OF ADMINISTRATION MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) 12 TABLE 5 DIAGNOSTIC RADIOPHARMACEUTICALS MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) 13 TABLE 6 JAPAN: RADIOPHARMACEUTICALS MARKET REVENUE, BY RADIOISOTOPES, 2008 – 2015 ($THOUSAND) 14 LIST OF FIGURES FIGURE 1 RADIOPHARMACEUTICAL MARKET, BY RADIOISOTOPES, 2008 – 2015 6 FIGURE 2 RADIOPHARMACEUTICALS: MARKET SEGMENTATION 8 MarketsandMarkets 4 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts EXECUTIVE SUMMARY Radiopharmaceuticals are medical formulations which contain radioisotopes and are safe for humans in diagnosis and therapy. Radioisotopes contribute in several sectors of the economy such as food processing, medicine, agriculture, and research. Radioisotopes in medicine are used either in liquid form (radiopharmaceuticals) or solid form (sealed source). Radiopharmaceuticals are defined as those pharmaceuticals which incorporate one or more radioactive isotopes. These are majorly used for diagnostic purposes. Technetium for single photon emission computed tomography (SPECT) and fludeoxyglucose (FDG) for positron emission tomography (PET) are the common radiopharmaceuticals used for diagnosis of various diseases. This market research report categorizes the global market for radiopharmaceuticals by types, indications, applications, and route of administration. This study is based on primary and secondary research, and analyzes the markets based on end-users, patents filed, and new developments. The report also studies and analyzes trends and opportunities affecting the market growth. MARKET SCENARIO Driven by the increasing incidence of cardiac and cancer diseases, early and accurate diagnosis, increasing radiopharmaceutical awareness market is and expanding estimated to application reach around segment, $XX billion the global in 2010. Radiopharmaceuticals are used for the diagnosis and treatment of various ailments such as cancer, cardiac, renal, and respiratory diseases among others. PET machines enable radiologists in early detection of cancer, cardiac, and Alzheimer’s disease among the patients. This would increase the demand for PET machines among the healthcare centers and providers. Similarly, SPECT scanners have been on the forefront to bring about significant changes in the diagnostic imaging equipment landscape with opportunities in the market for neuroendocrine tumor imaging. For diagnostic applications of radiopharmaceuticals, radioisotopes such as FDG for PET and technetium for SPECT are most commonly used. MarketsandMarkets 5 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts The global market for radiopharmaceuticals is significantly consolidated with players such as Covidien (Ireland), GE Healthcare (UK), ANSTO (Australia), IBA (Belgium), Cardinal Health (U.S.), and others. It is observed that in the study period, IBA, Nordion, and Cardinal Health lead the market with respect to competitive developments. On the other hand, GE Healthcare leads in terms of patents filed in the period between 2005 and 2011. GE Healthcare has filed XX% of the total patents filed between 2005 and 2011. FIGURE 1 RADIOPHARMACEUTICAL MARKET, BY RADIOISOTOPES, 2008 – 2015 2008 2009 2010 2015 Source: MarketsandMarkets Of all the radioisotopes technetium accounts for the largest share i.e. XX% in 2010. Globally in XX% of imaging processes, technetium is used as it has the advantage of generating an image with minimum risk to the patient. Rise in PET machine installations and increasing number of PET procedures would drive the demand for FDG. MarketsandMarkets 6 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 1 SUMMARY TABLE 1 RADIOPHARMACEUTICAL MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) Region 2008 2009 2010 2015 CAGR% (2010-2015) North America XX XX XX XX XX Europe XX XX XX XX XX APAC XX XX XX XX XX Japan XX XX XX XX XX ROW XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual report, MarketsandMarkets analysis North America commanded the largest share; i.e. XX% of the overall radiopharmaceuticals market in 2010; and is expected to reach $XX billion in 2015, at a CAGR of XX% for the same period. MarketsandMarkets 7 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 2 MARKET OVERVIEW 2.1 MARKET SEGMENTATION Radiopharmaceuticals are used for the diagnosis and treatment of various diseases such as cancer, cardiac, bone scan, and others. This report analyzes the radiopharmaceuticals market by types of isotopes, route of administration, and applications. Technetium accounts for the largest share; i.e. around XX% in the radiopharmaceuticals market, as it has a half-life of XX hours; thereby making it ideal for transportation. Moreover, handling with minimum damage to the patient, it can combine with XX different carrier molecules which are able to target many different organs. This segment consists of isotopes such as FDG, technetium, gallium, sodium iodide, rhenium, thallium, yttrium, erbium, and others. Majority of the radiopharmaceuticals are used for diagnosis (around XX%) with SPECT commanding XX% and PET commanding XX%. FIGURE 2 RADIOPHARMACEUTICALS: MARKET SEGMENTATION Radiopharmaceutical Market By Isotopes By Route of Administration By Application Treatment Diagnosis SPECT PET Source: MarketsandMarkets MarketsandMarkets 8 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts Radiopharmaceuticals used in SPECT are technetium, thallium, gallium, yttrium, erbium, and others. Of all these radiopharmaceuticals, technetium accounts for the largest share; i.e. around XX% share. In PET, FDG radiopharmaceutical is majorly used (around XX%). Radiopharmaceuticals are used for the diagnosis of various indications such as cancer, cardiac diseases, neuroimaging, bone scan, and others. MarketsandMarkets 9 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 3 RADIOPHARMACEUTICAL MARKET, BY ISOTOPES 3.1 LACK OF AVAILABILITY OF TECHNETIUM About XX% of Technetium is produced by XX reactors including Chalk River Reactor (Canada), BR-XX Reactor (Belgium), Orisis Reactor (France), High flux reactor (The Netherlands), and Safari Reactor (South Africa). These reactors have been in the business for a very long time around XX years. There has been shut down of two of the plants, leading to shortage of molybdenum; the raw material for technetium. This forces the medical fraternity as well as the industry players to find alternatives for technetium in terms of radioisotope; such as thallium for cardiac scan or imaging techniques that do not require technetium like X-Ray for bone scan. TABLE 2 TECHNETIUM MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($THOUSAND) Region 2008 2009 2010 CAGR% 2015 (2010-2015) North America XX XX XX XX XX Europe XX XX XX XX XX APAC XX XX XX XX XX Japan XX XX XX XX XX ROW XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual report, MarketsandMarkets analysis MarketsandMarkets 10 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts North America commanded the largest share – XX% – of the global technetium radioisotope market estimated at $XX million in 2010; and is expected to reach $XX billion in 2015, at a CAGR of XX% from 2010 to 2015. TABLE 3 NORTH AMERICA: THALLIUM MARKET REVENUE, BY COUNTRIES, 2008 – 2015 ($THOUSAND) Country 2008 2009 2010 2015 CAGR% (2010-2015) U.S. XX XX XX XX XX Canada XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual report, MarketsandMarkets analysis U.S. commanded the major share i.e. XX% of the North America thallium market estimated at $XX million in 2010; and is expected to reach $XX million in 2015, at a CAGR of XX% from 2010 to 2015. MarketsandMarkets 11 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 4 RADIOPHARMACEUTICAL MARKET, BY ROUTES OF ADMINISTRATION (ROA) TABLE 4 INHALATION ROUTE OF ADMINISTRATION MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) Region 2008 2009 2010 2015 CAGR% (2010-2015) North America XX XX XX XX XX Europe XX XX XX XX XX APAC XX XX XX XX XX Japan XX XX XX XX XX ROW XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual report, MarketsandMarkets analysis North America commanded the largest share i.e. XX% of the global inhalation route of administration market estimated at $XX million in 2010; and is expected to reach $XX million in 2015, at a CAGR of XX% from 2010 to 2015. MarketsandMarkets 12 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 5 RADIOPHARMACEUTICAL MARKET, BY APPLICATIONS TABLE 5 DIAGNOSTIC RADIOPHARMACEUTICALS MARKET REVENUE, BY GEOGRAPHY, 2008 – 2015 ($MILLION) Region 2008 2009 2010 CAGR% 2015 (2010-2015) North America XX XX XX XX XX Europe XX XX XX XX XX APAC XX XX XX XX XX Japan XX XX XX XX XX ROW XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual report, MarketsandMarkets analysis North America commanded the largest share i.e. XX% of the global diagnostic radiopharmaceutical market estimated at $XX billion in 2010; and is expected to reach $XX billion in 2015, at a CAGR of XX% from 2010 to 2015. MarketsandMarkets 13 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts 6 GEOGRAPHIC ANALYSIS (CONSUMPTION) 6.1 JAPAN Japan accounts for XX% of the global market for radiopharmaceuticals. The demographic factors of Japan are boosting the growth of the market. The country has strong local players such as Fujifilm. It has to import most of the raw material from the other countries. TABLE 6 JAPAN: RADIOPHARMACEUTICALS MARKET REVENUE, BY RADIOISOTOPES, 2008 – 2015 ($THOUSAND) Radioisotope 2008 2009 2010 2015 CAGR% (2010-2015) Fludeoxyglucose XX XX XX XX XX Technetium XX XX XX XX XX Gallium XX XX XX XX XX Sodium iodide XX XX XX XX XX Iobenguane XX XX XX XX XX Rhenium XX XX XX XX XX Samarium XX XX XX XX XX Thallium XX XX XX XX XX Yttrium XX XX XX XX XX Erbium XX XX XX XX XX Others XX XX XX XX XX Total XX XX XX XX XX Source: Expert interviews, Annual reports, U.S. Industry and trade commission, MarketsandMarkets analysis MarketsandMarkets 14 Global Nuclear Medicine (Medical Isotopes/Radioisotopes/Radiopharmaceuticals) Market in PET/SPECT Imaging & Therapy – Competitive Landscape, Current Trends & Forecasts Technetium radioisotope accounted for the largest share; i.e. XX% of the overall market for radioisotopes in Japan in the year 2010. This segment is expected to reach $XX million by 2015, at a CAGR of XX% for the same period. MarketsandMarkets 15
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