VOL. 20, NO. 3 ISSN 15294722 SEPTEMBER 2013 Optimal Thyroid Function with Superior Nutrition Biotics Research Corporation offers specific products to support normal, healthy thyroid function; products which may be appropriate for your patient’s individual needs. • ADHS® (adrenal support) • ADB5-Plus™ (adrenal support) • Cytozyme-AD™ (raw neonatal adrenal) • GTA® (endocrine support) • Meda-Stim™ (endocrine support) • Thyrostim™ (endocrine support) • Iodizyme-HP™ (high potency iodine) • Liquid Iodine Forte (potassium iodide) All Biotics Research Products are Gluten Free! (800) 231-5777 www.bioticsresearch.com Follow us on These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. 720 Oak Knoll Rolla, MO 65401 Telephone: (573) 3418448 Fax: (573) 3418494 Email: [email protected] is published quarterly. Publication months are March, June, September and December, barring any unusual or unforeseen circumstances. News items and/or letters pertaining to natural health care are welcome. The editorial staff reserves the right to edit and/or reject all material received. Letters to the editor may be condensed in order to fit the allotted space. An address and telephone number where the author may be reached during normal business hours should also be included for verification purposes. Deadline for article submission is the 5th of the month preceding publication. A subscription to is $50. A free one year subscription will be given to anyone who submits a case study or scientific article which is accepted for publication. (This does not include letters to the editor.) Please notify Clint Publications if you change your address or office name, or we cannot be responsible for proper delivery of your journal. Advertising deadline is the 5th of the month preceding publication. For advertising rates or information, contact Clint Publications. The opinions expressed in are presented for the purpose of providing an open forum for unbiased case studies, contemporary ideas and discussion of matters relevant to natural health care. Its primary mission is to educate and inform those especially interested in promoting natural health care as a primary treatment. The opinions expressed in do not necessarily reflect the opinions and policies of Clint Publications or SEPTEMBER 2013 ……. ……. Spring 2006 SEPTEMBER MARCH 2011 2013 402 West County Road D Saint Paul, MN 55112 877-474-5767 Jennifer A. Collins, Ph. D. Karla Walker, Pharm. D. Mark G. Catlin, M. D. Patient Test Order Information PINC-POWER MED INC #16 MUNICIPAL DR STE E ARNOLD, MO 63010 Name: Patient ID: Patient Phone: DOB: Sex: MALONEY,JACQUELYN 08/16/1935 Age: 77 Collected: Received: Reported: 06/27/2013 06/29/2013 07/08/2013 1:47 PM 9:10 AM Report Status: FINAL Account #: 50453817 Ordered By: Requisition #: MA1099431 Accession #: F5416438 Test Result Flag VAP CHOLESTEROL TOTAL LDL-CHOL 220 H (Desirable range <100 mg/dL for CHD, Diabetes, or its equivalent) TOTAL HDL-CHOL 69 TOTAL VLDL-CHOL 44 H TOTAL CHOL 333 H TRIGLYCERIDES 245 H TOTAL APO B100 164 H NON-HDL CHOL 264 H Lp(a) CHOL 9.0 IDL CHOL 49 H LDL-R (Real)-C 162 H TOTAL LDL-C 220 H REAL-LDL SIZE PATTERN A [__________________] Pattern B Small, Dense LDL [_______] Pattern A/B Units Reference Range mg/dL <130 mg/dL mg/dL mg/dL mg/dL mg/dL mg/dL mg/dL mg/dL mg/dL mg/dL >=40 <30 <200 <150 <109 <160 <10 <20 <100 <130 A [______*________] Pattern A Large Buoyant LDL REMNANT LIPOPROTEINS 72 H mg/dL Due to the presence of additional risk factors, consider lowering LDL-C goal CONSIDERATION NO HDL-2 26 mg/dL HDL-3 44 mg/dl VLDL-3 23 H mg/dL LDL4 0.0 mg/dL LDL3 38.5 mg/dL LDL2 57.7 mg/dL LDL1 66.2 mg/dL <30 No GENDER NEEDED GENDER NEEDED <10 Analysis performed by Atherotech Inc; 201 London Parkway Suite 400, Birmingham, AL 35211 Page: 1 of 1 vC2.2 Certified Integrative Chiropractic Physician g n i m o C n o So 100 Hour Certification Program The philosophy of integrative medicine Integrative assessment of patient history and physical exam The integrative approach to disease Disease prevention Clinical botanical medicine Clinical homeopathy Clinical nutrition Conservative care for adult and pediatric acute and chronic conditions Basic and advanced blood chemistries Advanced functional diagnostic testing Cast Your Location Vote □ Charlotte, NC □ Baltimore. MD □ Dallas. TX □ Omaha, NE [email protected] □ Pittsburgh, PA □ Springfield, NJ □ Canton, OH □ Chicago. IL www.drkessinger.com 573-341-8448 □ Albuquerque, NM □ Boston, MA □ Phoenix, AZ □ Los Angeles, CA [email protected] Cervical nerve root irritation, from any reason, may not only cause headaches but also a chronic, generalized hypertonicity with accompanying somatic cervicobrachial symptomatology. Cluster headaches (CH) are characterized by sudden paroxysmal attacks of severe head pain that occur in a collection of individual assaults experienced over days, weeks, or even months. An abrupt and total remission from attacks may last for a year or more with recurrences possible at anytime without warning. CH is far more common in men and Headache is one of the most common disorders, and by far, the most common neurological complaint. In all chronic headache patients, suspect spinal subluxations and allergies. Headaches are divided into two groups; functional and pathological. Functional headaches are usually chronic and not generally regarded as dangerous. Pathological headaches are usually caused by an underlying condition, such as trauma. The most frequent include tension headache, vertebrogenic headache, cluster headache, sinus headache, vascular headache, and temporal arteritis. A nonspecific headache characterized by a dull pain reported throughout the head. The patient will usually report neck pain with this type of headache. SEPTEMBER 2013 have a selective sensitivity to a variety of substances that precipitate or aggravate the headache. Tobacco smoke, alcohol, stress, perfumes, oversleeping, fatigue, environmental exposure and neck flexion and rotation. CH frequently coincide with the seasons, indicating allergies. Other conditions reported to be associated with CH include gastrointestinal symptoms, transient muscular twitching, paresthesia, and arrhythmias. CH victims are usually restless, preferring to walk around during the attack. The cause of CH is speculated to be either neurological and/or vascular. Clearly both are involved. One hypothesis postulates the pathology affects the brainstem causing a parasympathetic stimulation of the vagus nerve giving rise to the various symptoms. The sinus headache may be associated with infection, inflammation, and/or congestion of the nasal sinuses of the head. The pain is generally described as dull or gnawing that may range from mild to severe. The pain is characteristically localized over the affected part. Sinus headaches may be misdiagnosed as CH's. In CH the unilateral pain appears suddenly, is severe and constant, and drastically increased by reclining. The vascular headache is characterized by a throbbing pain which is often synchronized with the pulse, and can be serious and disabling. Most vascular headaches occur due to the dilation of the extracranial arteries that are branches of the carotid arteries and located mainly in the scalp. The vascular headache is divided into two classes, and . Many different clinical types of migraine are described in the literature. All migraine headaches are characterized by severe, throbbing pain that is customarily unilateral. They are often associated with anorexia, nausea, vomiting, dizziness, cold hands, Dr. Jay Kessinger As Governor Mike Huckabee stated on his syndicated show, “ Unhealthiness is becoming the norm’ and not the exception. Rumors abound of how our children will not experience the longevity that we’ll have, yet at the same time, through our increased longevity, we are more apt than our parents to be plagued with disabilities. Many of these haven’t been known to humanity before. The toxic world in which we reside (laden with so many nonnutritious food sources, less physically exerting task masters, and charlatan crazes) is leading us down a potentially physiologically destructive pathway. Several theories presently abound (from a full spectrum of think tanks) toward reaching a solution of our predominantly manmade dilemma of untimely sickness and demise. One such theory is to return to the primitive conditions from the times of yore. The problem with this is its inherent lack of creature comforts that we’ve come so accustomed to that they are considered a necessity rather than an extravagance. Another idea is to reside within a bubble, continually being protected from harmful toxins of the outside world. An obvious fallacy of this model is twofold. Firstly, there is the impossibility of absolute separation from the bacterial, et.al. infested microscopic world of nature at its tiniest. Most importantly, there cannot be a strong constitution of health without stress; i.e., immunological, neurological, and physiological. Medicinally, our health maladies are treated singularly with little attention being paid to the causative factors. Some examples of this are hypertension or G.E.R.D. medications used long term. There are also ADHD and SEPTEMBER 2013 asthmatic medications utilized chronically with little investigation or correction toward the etiological elements that led to the current syndrome. Historically and realistically, we are wonderfully made and enabled with near countless abilities to compensate for less than optimal nutritional intake, severe physical injury, inadequate oxygen availability and chronic toxic exposure, aswellas organ system malfunction. We can have a multitude of maladies going on singularly or simultaneously, especially on a chronic basis, with the occasional OTC symptomrelieving medication as deemed . We are able to carry a full load until we buckle at our knees and succumb to our illness. Holistically, through the DABCI model of chiropractic care, we identify the organ systems involved, determine the severity of dysfunction(s) present and correct the maladies amendable to natural health care provision. We make appropriate referrals as necessary, keeping the patient fully informed of the working diagnosis and the treatment protocol being prescribed. Most important are the reexaminations scheduled throughout the prescribed treatment procedures to assure both patient and practitioner of the efficiency of our chosen protocol. The DABCI system of health care is obviously the superior choice, provided immediate death is not imminent; however, as with many other truths throughout history, the DABCI method of health care provision is met with disdain and relegated not worthy by those wielding the largest health care dollar axe; i.e., third party health care payers. This financial hardship can be overcome by going to a cashforservice payment system. The current diagnostic and procedural codes are provided to each person we have the privilege to serve, ensuring that they can file their claim with their 3rd party payer. This keeps cost reasonable and leads to the proper placement of anger. The doctor/patient relationship can continue to focus on health, while the haggling can be between the patient and their insurance company as it should be. trans The DietHeart Disease Hypothesis makes three pri mary assumptions: 1.) Intake of saturated fat causes high total cholesterol and lowdensity lipoproteins (LDLs) 2.) High total cholesterol and LDL are correlated with heart disease 3.) High dietary intake of saturated fats is correlated with high total cholesterol and LDL, and therefore, causes heart disease. While the first two correlative assumptions have received wide support in the literature, recent metaanalysis has concluded that dietary fat is not sig nificantly correlated with coronary heart disease or car diovascular disease.1 It is just as wellknown, yet less publicized, that satu rated fat intake may also: Increase or "good" cholesterol. Decrease Lower , an independent marker of heart disease risk. Improve the , also a strong independent marker of heart disease risk.2,3,4,5,6,7,8 So while the last century of diet guidelines have fo cused on the correlation of saturated fat, LDL's, and Total Cholesterol with heart disease, eating a diet high in saturated fats may actually be heart . How so? While saturated fat intake undoubtedly increases LDL's and Total Cholesterol; its beneficial effect on other markers of heart disease may be more profound. The "beneficial" effect may go against everything you have learned up to this point about saturated fats, cholesterol, and their proposed links to heart disease. The research community has largely ignored evidence with regards to the potentially healthy effects of satu rated fats on Lp(a), HDL, and the Total Choles terol:HDL ratio. Instead, much of the research has focused on saturated fat intake and its association with high LDLs. Since high LDLs are considered a risk factor for heart disease, researchers have prematurely jumped to the conclusion that saturated fats are to blame. Our understanding of the connection between LDLs and Heart Disease has also adapted. We now know that different types of saturated fats and carbohydrates have differential effects on . Heart disease is not necessarily associated with total LDLs, but it is definitely associated when there are nu merous LDLs that are more "small and dense" in size. The larger, "fluffier" LDLs may be heart protective.9 For instance, you may have high LDLs, but the major ity of them may be of the protective, "large and fluffy" Spring 2006 SEPTEMBER 2013 variety. On the flip side, you may have "normal" levels of LDLs, but the majority of them could be of the risky, "small and dense" variety. It is these findings that may help explain why 50% of 136,905 individuals hospitalized with coronary heart disease had "normal" levels of cholesterol, HDL, and LDL at the time of their hospitalization.10 Findings now suggest that total cholesterol, LDLs, and HDLs are not the most reliable indicators for heart disease risk. LDL particle number is now accepted as one of the strongest markers of heart disease risk, po tentially even more than traditional markers like total cholesterol and LDLs.11 As discussed, an increase in saturated fat intake decreases the risk of heart disease; therefore, a decrease in saturated fat intake should also be associated with an increase in heart disease risk. What does the research say about this? In line with what you have been taught before, a decrease in saturated fat intake is associated with a de crease in LDL. But as you now know, the story does not end there. Levels of healthy HDLs also decrease and unhealthy Lp(a) levels increase. When you choose to lower saturated fat intake, you have to balance the "improvements" in LDL numbers with the negative effects on levels of HDL and Lp(a).12 Clinicians and researchers alike are now challenged with a broader picture of heart disease risk than what we've been taught over the last century. The American Heart Association still recommends a diet that is comprised of only 7% or less calories from saturated fat,13 and interestingly, it has not given clear guidance as to what to substitute the saturated fats with. Let's take a look at what happens when you substitute saturated fat intake with polyunsaturated fats or carbo hydrates. The research community has focused on the substitu tion of polyunsaturated fats (PUFAs) for saturated fats as a means of reducing heart disease risk based on the conventional dietheart disease hypothesis. When you substitute PUFAs for saturated fats, heart SEPTEMBER 2013 disease risk does decline, but it is impossible to tell if the decline is because of adding more PUFAs to the diet, consuming less saturated fats, the combination of adding PUFAs and reducing saturated fats, or if the correlation is due to other unknown variables not yet considered.14,15,16 The underlying assumption appears to be that PUFAs are associated with lower levels of LDLs and, there fore, are correlated with less incidence of heart disease; ultimately, researchers have generally concluded that PUFAs are heart protective. As we know from my earlier discussion however, the widely accepted correlation between LDL levels and heart disease is not cut and dry yet researchers still make the assumption that LDLs are bad, citing the same correlative research articles over and over again. Again, this is just a , and the potentially healthy effects of dietary fats on HDL, Total Choles terol:HDL and Lp(a) are still largely ignored. Complicating matters more, a recent metaanalysis reviewed that an increase in PUFA intake was associ ated with a 13.3% reduction in Total Cholesterol as expected; but the substitution of PUFAs for saturated fats was also associated with an in mortality. The authors proposed that the higher intake of PUFAs was associated with increases in oxidized metabolites (which make up most of the fatty acids in oxidized LDL). Nevertheless, their findings went counter to previous assumptions in the literature; and the authors were careful to indicate that the trouble with PUFAs may be when they are consumed in rather than when found naturally in whole foods such as nuts and vegetables.17 Excess dietary polyunsaturated fat is nearly impossible to achieve with a diet of whole foods. It gets even trickier when you consider that oxidized LDLs are an often proposed cause of atherosclerosis. When you look at the composition of arterial plaques, however, they are predominantly comprised of oxidized polyunsaturated fats, not saturated fats. Without clear guidance as to what to substitute saturated fats with, most Americans have made up for their saturated fat intakes with carbohydrates, espe cially refined carbohydrates and added sugars.18 It is wellestablished that high intake of refined carbo hydrates is associated with increased risk for type 2 diabetes and ischemic heart disease.19 hash browns, pepperoni pizza... When you substitute carbohydrates for saturated fat, little to no benefit is seen in reducing heart disease risk unless the carbohydrates added are unrefined and have a low glycemic index.20 When research subjects fill out food frequency ques tionnaires, a check for "hamburger" is a check for satu rated fat. But what do we eat hamburgers with? Typi cally a white, refined carbohydrate bun, along with a high sugar condiment like ketchup. Eating a hamburger is not a simple categorization. The "white bread" and "condiment" part tends to be ignored. Additional analysis revealed that when saturated fat intake was replaced with highcarbohydrate, high gly cemic index foods, it was associated with a higher risk of a heart attack. When the opposite occurred (substituting saturated fats with low glycemic carbohy drate foods) it was associated with a lower risk of a heart attack.21 Further, researchers suggest that even if we decided that saturated fats are risky for heart disease, the effect of high intake of refined carbohydrates may cause even worse metabolic damage.22 So it would appear that more focus should be placed on reducing refined carbohydrates, added sugar and proc essed foods, and less focus should be placed on reduc ing intake of dietary saturated fats. There is no question that LDLs are associated with higher levels of heart disease. But as we've established, the story goes deeper when it comes to saturated fats and cholesterol, LDLs, LDL size, LDL particle num ber, HDLs, Lp(a), Total Cholesterol:HDL ratio, and subsequent “net” risk for heart disease. First, cholesterol intake actually has little to do with cholesterol levels in the bloodstream. As intake increases, the body's natural production of cholesterol decreases. As the intake of cholesterol de creases, the body's production ramps up, increasing levels. Paradoxically, you can have elevated, poten tially harmful levels of cholesterol due to not eating enough cholesterol. The research now suggests that saturated fat intake may have a greater beneficial effect on HDLs, Total Choles terol:HDL, Lp(a), and LDL Particle Size and Number. When you substitute saturated fat intake with refined carbohydrates and other processed oils high in PUFAs, you may actually be increasing your health risk. When you think of typical American foods, what do you think of? Hamburgers and french fries, bacon and Spring 2006 Additionally, not all studies control for processed vs. unprocessed meat as sources of saturated fat. One study did show an association between processed and unprocessed meat with stroke mortality, but the analysis was still assessed by an FFQ.23 FFQ's do accurately reflect saturated fat intake, but the important grey areas are not taken into account. An additional study from the made a really interesting observation, however. The researchers looked at total cheese intake and the use of butter in cooking (high sources of saturated fat). They failed to find an association with heart attacks for both, but that was not the interesting part. When they controlled "how" the butter was consumed, they found when it was consumed on bread, it was asso ciated with heart attack risk; when consumed alone, no correlation was found.24 In April 2013, the NY Times and other publications sent the media on a fury announcing a new proposed link between red meat and heart disease.25 The researchers found that those eating red meat were metabolizing its carnitine content into trimethylamine Noxide (TMAO). The study also showed a correlation between TMAO levels and heart disease risk.26 The media concluded that a new link between heart disease and red meat had been discovered, yet flaws in the as sociation surfaced. One of the highest natural sources of TMAO is fish. TMAO is actually the chemical that gives fish its "fishy" smell. Fish intake has largely been associated with heart disease protection. That was the first glaring problem with their analysis. The second problem took a little deeper analysis. The mechanism for the conversion of carnitine to TMAO SEPTEMBER 2013 proposed by the researchers was the overgrowth of cer tain species of bacteria in the gut such as . What might increase the level of bacteria in the gut? A highgrain diet has been proposed as root cause for the overgrowth.27 The media could have just as easily reported that a new link was discovered between heart disease and grains, but the bias toward red meat and saturated fat was maintained in the coverage. fatty acids (TFAs) comprise 25% of total fat in ruminant fats (from cows, goats, sheep, etc.) but com prises 5060% of total fat in partially hydrogenated vegetable oils. Naturally found TFAs differ from those found in par tially hydrogenated vegetable oils because of the place ment of the double bonds. The most commonnaturally occurring TFA is vaccenic acid and is the precur sor to conjugated linoleic acid (CLA or alpharumenic acid).28 While CLA may still have a deleterious effect on lipid profiles like other fatty acids,29 it may also offer multiple beneficial effects for fat and bone metabolism, immune function, as well as risk of cardiovascular dis ease and cancer.30 It is generally considered a healthy fat when compared to the TFAs found in partially hy drogenated vegetable oils, but the research is still young. Dietary TFAs raise LDL cholesterol and total choles terol, and lower HDL cholesterol31 TFAs have also been reported to increase the stickiness of platelets in the blood32 as well as levels of Lp(a).33 The news is troublesome as up to 70% of the vegetable oils used in foods like crackers, cookies, pastries, cakes, snack chips, candies and fried foods are partially hydrogenated. Because of this, it is very difficult to assess TFA intakes among populations.28 Food companies are only required to list fat (TF) on the label if the TF content is more than 2g per serv ing. If the label reads partially hydrogenated fat in the ingredient list, but 0g of total TF, it is likely that the product contains TF, but less than 2g per serving. Estimates for American intake of TFAs range as high as 38.7g/day.28 Other possible adverse effects of TFAs include, but are not limited to: Cognitive decline Metabolic syndrome Infertility Compromised fetal development 33,34 While TFAs naturally found in milk, cheese, and rumi nant meats may be healthy, one might consider staying away from pastries, cookies, snacks, fried foods, mar garine, and other processed foods containing unnatural partially hydrogenated vegetable oils. 1.) Saturated Fat and Cholesterol may not cause heart disease. They may actually be heart protective. 2.) Be cautious of processed polyunsaturated fat (PUFA) oils that have been used to substitute satu rated fats in our diet. PUFAbased oils may in crease risk of vessel damage from oxidized LDLs. Be particularly careful when these oils are: Cooked at high heat Stored for long periods of time Exposed to long periods of air/light Partially hydrogenated/hydrogenated Consumed with refined, processed, high glycemic index carbohydrates 3.) Stay away from refined, processed, high glycemic index carbohydrates. In particular, white breads, refined grains and added sugars. 4.) Stay away fromTFAs found in margarine, pastries/ baked goods, and partially hydrogenated/ hydrogenated oils. Some natural fats such as conjugated linoleic acid (CLA) may offer health benefits. SEPTEMBER 2013 1) SiriTarino PW, Sun Q, Hu FB, Krauss RM. Meta analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. 2010;91(3):53546. 2) Mozaffarian D, Micha R, Wallace S. Effects of coronary heart disease of increasing polyunsatu rated fat in place of saturated fat: A systematic re view and metaanalysis of randomized controlled trials. 2010;7(3):e1000252. 3) Muller H, Lindman AS, Brantsaeter AL, Pedersen JI. The serum LDL/HDL cholesterol ratio is influ enced more favorably by exchanging saturated with unsaturated fat than by reducing saturated fat in the diet of women. 2003;133(1):7883. 4) Ginsberg HN, KrisEtherton P, Dennis B, Elmer PJ, Ershow A, Lefevre M, Pearson T, Roheim P, Ramakrishnan R, Reed R, Stewart K, Stewart P, Phillips K, Anderson N. Effects of reducing dietary saturated fatty acids on plasma lipids and lipopro teins in healthy subjects: the Delta Study, Protocol 1. 1998;18:441449. 5) Schaefer EJ, LamonFava S, Jenner Jl, McNamara JR, Ordovas JM, Davis CE, Abolafia JM, Lippel K, Levy RI. Lipoprotein(a) levels and risk of coronary heart disease in men. the lipid Research Clinics Coronary Primary Prevention Trial. 1994;271(13):9991003. 6) Hoenselaar R. Saturated fat and cardiovascular dis ease: the discrepancy between the scientific litera ture and dietary advice. 2012;28(2):118 23 7) Lewington S, Whitlock G, Clarke R, Sherliker P, Emberson J, Halsey J, Qizilbash N, Peto R, Collins R. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a metaanalysis of individ ual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2008;372(9635):292. 8) Mensink RP, Zock PL, Kester AD, Katan MB. Ef fects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on se rum lipids and apolipoproteins: a metaanalysis of 60 controlled trails. Am J Clin Nutr 2003;77 (5):114655. 9) SiriTarino PW, Sun Q, Hu FB, Krauss RM. Satu rated fat, carbohydrate and cardiovascular disease. Am J Clin Nutr 2010;91(3):502509. 10) Sachdeva A, Cannon CP, Deedwania PC, Labresh KA, Smith SC Jr., Dai D, Hernandez A, Fonarow Spring 2006 GC. Lipid Levels in patients hospitalized with coronary artery disease: an analysisof 136,905 hos pitalizations in Get With The Guidelines. Am Heart J 2009;157(1):111117. 11) Kathiresan S, Otvos JD, Sullivan LM, Keyes MJ, Schaefer EJ, Wilson PW, D’Agostino RB, Vasan RS, Robins SJ. Increased small lowdensity lipo protein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study. Circulation 2006;113(1):209. 12) Ginsberg HN, KrisEtherton P, Dennis B, Elmer PJ, Ershow A, Lefevre M, Pearson T, Roheim P, Ramakrishnan R, Reed R, Stewart K, Stewart P, Phillips K, Anderson N. Arteriosclerosis, Throm bosis, and Vascular Biology 1998;18:441449. 13) Lichtenstein AH, Appel LJ, Brands M, Carnethon M, Daniels S, Franch HA, Franklin B, Kris Etherton P, Harris WS, Howard B, Karanja N, Le fevre M, Rudel L, Sacks F, Van Horn L, Winston M, WylieRosett J. Diet and lifestyle recommenda tions revision 2006: A scientific statement from the American Heart Association Nutrition Committee. Circulation 2006;114:8296. 14) Mozaffarian D, Micha R, Wallace S. Effects on coronary heart disease of increasing polyunsatu rated fat in place of saturated fat: A systematic re view and metaanalysis of randomized controlled trials. PLoS Med 2010;7(3):e1000252. 15) SiriTarino PW, Sun Q, Hu FB, Krauss RM. Satu rated fat, carbohydrate, and cardiovascular disease. Am J Clin Nutr 2010;91(3):502509. 16) Hooper L, Summerbell CD, Thompson R, Sills D, Roberts FG, Moore H, Smith DG. Cochrane Data base Syst Rev. 2011;(7):CD002137. 17) Ramsden CE, Zamora D, Leelarthaepin B, MajchrzakHong SF, Faurot KR, Suschindran CM, Ringel A, Davis JM, Hibbeln JR. BMJ 2013;346:e8707. 18) Hu FB. Are refined carbohydrates worse than satu rated fat? Am J Clin Nutr 2010;91(6):15411542. 19) Hu FB, Willett WC. Optimal diets for prevention of coronary heart disease. JAMA 2002;288 (20):256978. 20) Nagata C, Nakamura K, Wada K, Oba S, Tsuji M, Tamai Y, Kawachi T. Total fat intake is associated with decreased mortality in Japanese men but not in women. J Nutr. 2012;142(9):17131719. 21) Jakobsen MU, Dethlefsen C, Joensen AM, Stegger J, Tiǿnneland A, Schmidt EB, Overvad K. Intake of carbohydrates compared with intake of saturated fatty acids and risk of myocardial infarction: im portance of the glycemic index. Am J Clin Nutr. 2010;91(6):17648. SEPTEMBER 2013 22) Hu FB. Are refined carbohydrates worse than satu rated fat? Am J Clin Nutr. 2010;91(6):15412. 23) Bernstein A, Pan A, Rexrode KM, Stampfer M, Hu FB, Mozaffarian D, Willett WC. Dietary protein sources and the risk of stroke in men and women. Stroke 2012;43:637644. 24) Patterson E, Larsson SC, Wolk A, Åkesson A. As sociation between dairy food consumption and risk of myocardial infarction in women differs by type of dairy food. JN 2013;143(1):7479. 25) Kolata G. Culprit in heart disease goes beyond meat's fat. The New York Times April 7 2013, http://www.nytimes.com/2013/04/08/health/study pointstonewculpritinheartdisease.html?_r=2& (accessed August 5, 2013). 26) Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Bi4rtt EB, Fu X, Wu Y, Li L, Smith JD, Didonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL. Intestinal mi crobiota metabolism of Lcarnitine, a nutrient in red meat, promotes atherosclerosis. 2013;19(5):57685. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini s, Pieraccini G, Lionetti P. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. 2010 Aug 17;107(33):146916. 28) Enig MG. Know your fats: the complete primer for understanding the nutrition of fats, oils, and choles terol. Silver Spring, MD: Bethesda Press, April 2000. 29) Wanders AJ, Brouwer IA, Siebelink E, Katan MB. Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects. 2010;5(2):e9000. 30) Dilzer A, Park Y. Implication of conjugated li noleic acid (CLA) in human health. 2012;52(6):488513. 31) Mensink RP, Katan MB. Effect of dietary fatty acids on highdensity and lowdensity lipo protein cholesterol levels in healthy subjects. 1990;323(7):43945. 32) Wahle KW, Peacock LI, Taylor A, Earl CR. Effect of trans fatty acids on platelet function. 1994;75:1836. 33) Kochan Z. Karbowska J, BabiczZielinska E. Die tary fatty acids and metabolic syndrome. 2010; 64:6508. 34) Bhardwaj S, Passi SJ, Misra A. Overview of fatty acids: biochemistry and health effects. 2011;5(3):1614. SEPTEMBER 2013 35) Weinberg SL. The dietheart hypothesis: a critique. 2004;43(5):73133. 51. 91 . 0 . 34 100 . 23 . 0 . 18 CMYK Assembly ® LOWER BACK PAIN RELIEF Pantone 255 Pantone 3015 Gray Scale Assembly E RE douts F Han t ble ien Pat availa • Comfortable • Portable • Easy to use • Designed for patient in-home use 30 Day conditional Money back guarantee LASHAW DISTRIBUTORS LTD. 9631 Bakerview Drive Richmond, B.C., Canada V7A 2A2 Tel: ....................................(604)270-4263 Fax:................................... (604)277-2154 Toll Free: ..........................1-800-667-7795 C.O.D. Or prepay By cheque Website: ........................ www.invertrac.com E-mail: .................... [email protected] Recently I met a Harvard trained Cardiologist in a so cial venue. He told me that only double blind studies were of value. This led me to my compulsive obsessive tendency to think, and here are some of the thoughts that emerged from the occasion. First, let me say that it appears to a country boy, such as I, that this is an elitist viewpoint. How much of the knowledge in this world has no such double blind his tory? How many double blind studies were done be fore the first mitral valve was replaced, and since the answer is none, shouldn’t we stop mitral valve replace ments until such double blind evidence can elucidate the efficacy of such procedures? Double blind has been used as a whipping post for those of us who use natural medicine because so much of what we do is based on clinical evidence. If double blind studies are the only good way to obtain valuable information and if clinical studies count for nothing, won’t we have to put most medical procedures on hold? Many things do not readily lend themselves to the dou ble blind protocol. Manual manipulation is one of these things. Does this mean that we must forego all manual manipulation until such studies can be done? This is not to say that double blind studies are not use ful and desirable whenever they can be applied. The reason this method has been successful in the testing of many kinds of medicine is that the process is beyond partisan control, and the results are free of interpreta tive bias. Double blind works well when the response is linear and the process being examined is completed within the sixmonth test period. Many drugs do lend themselves to the double blind format, but even they have some weaknesses. In many instances, the medica tion in question is compared to a placebo. A placebo, by definition, does absolutely nothing. How difficult is it to compete with nothing and just how good is the drug that has won such a contest? This leads us to an other obvious fault. Spring 2006 I would ask Dr. Double Blind how he knows beyond any shadow of a doubt that his placebo has no action whatsoever. Ask any person you meet to give you an example of a placebo and at least some of them will say “a sugar pill.” You and I know that sugar has very sig nificant effects on the human body and many of them are very detrimental. Of course Dr. Double Blind knows that, so if he were developing a research study, he would not pick sugar for his placebo. What would he pick and how would he determine that it has no long term physiological effects? Even when we have double blind studies, it sometimes isn’t enough; there can be other factors. Was the study done at a university? Was the researcher a famous sci entist? What are his credentials? Was this study pub lished in a peer reviewed journal? Was the study done in the United States of America? Does the last question imply that we can’t learn from third world researches, but they have to learn from us? Oh my God, now I am starting to sound elitist! So let’s give Dr. Double Blind the criteria that he re quires. Let’s say it is a double blind study, done at a major university by a Nobel laureate and published in a peer reviewed paper such as JAMA. So if the therapies allopathic doctors are using are sacrosanct because they are based on the gold standard of research, why do we keep getting reports, from such sources as the Journal of the American Medical Association, among others, that adverse drug reactions are one of, if not the leading cause of death in this country? In his book, The New Arthritis Breakthrough, The Only Medical Therapy Clinically Proven to Produce Long Term Improvement and Remission, Henry Scammell says the following: “ ” Bruce Pomeranz M.D., Ph.D., from the University of Toronto analyzed 39 studies of Adverse Drug Reac SEPTEMBER 2013 tions in the United States to estimate the incidence of serious and fatal reactions in hospitalized patients. The results were that 106,000 deaths each year are caused by patented medicines. It did not include outpatients, mistakes, or accidents; if it had, the number would have been much larger. This study was published in the Journal of the American Medical Association, April 15th, 1998. I wonder how consoling it is to the families of the deceased to learn that all of the drugs involved were approved by double blind studies. Barbara Starfield M.D., of Johns Hopkins School of Hygiene and Public Health, confirmed the above report and shed light that the numbers were actually much higher. This was reported in JAMA, July 26th, 2000. 284(4):21845. To add interest to the facts, Dr. Star field passed away and the cause of death has been at tributed to her medical care. Implicated is the com monly prescribed and widely advertised drug Plavix, a drug proven by double blind studies and approved by the FDA. No matter how double blind the study is, if the animal tested is inappropriate for the test, the results will be meaningless. A perfect example of this is using rabbits for cholesterol studies. Cholesterol does not exist in plants but only in animals. Rabbits don’t eat animals. To use rabbits in cholesterol studies, one has to force feed cholesterol because they won’t eat it otherwise. Since rabbits are not designed to handle cholesterol in their diet, the results are meaningless if you are trying to correlate them with humans. The heart of many research papers lies in the statistical details. It has been said that Statistics are like a bikini; what it reveals is interesting but what it conceals is vi tal. The difference frequently lies in whether the results are a relative risk or an absolute risk. Once it is known whether the researcher is using relative or absolute risk factors, one needs to look at the NNT factor (number needed to treat). How many people must be treated be fore one person has the desired effect? It is not possible to cover these factors thoroughly in this paper, but every doctor should make sure that he or she under stands these concepts. Pharmaceutical companies have repeatedly proven that they will tinker with the statis tics to get their research projects approved. Each of us must make sure that we understand the game when we read these research papers. You can go to Biotic’s Tuesday Minute (www.tuesdayminute.net) and find an introduction of the answers if you want to refresh your understanding of how to interpret a research paper. SEPTEMBER 2013 Once you have done your double blind study, or any other study, you must interpret the data. It is not diffi cult to find relationships between two parameters. The problem starts when one wants to define the cause and the effect. Just because there is a correlation between cholesterol and heart disease, does not guarantee that increased cholesterol causes heart disease. Could it be possible that heart disease causes cholesterol to in crease? An example of this logic can be illustrated by the fact that every time you see a house on fire, you see a fire truck. This is not proof that fire trucks are a major cause of house fires. As wonderful as the double blind design is, it contributes very little to the interpretation of cause and effect. Last, but not least, is the question of integrity. We Americans, and probably the rest of the world, have come to place research on a pedestal. It is one of the last refuges where we can place trust. When I was young, there were many things that we believed in and trusted: policemen, teachers, clergy, doctors, almost anyone in authority and most of all, an almighty God. For many people all of the above are no longer a court of comfort when we need one. Until recently, research has remained something that most people could believe in. It gives me no joy to report that people are now begin ning to lose this refuge. The government has brought many law suits against pharmaceutical companies in recent years. Fraud, inappropriate charges to Medicare, and just general crookedness that would land you or me in jail have become commonplace. Pharmaceutical companies are now financing most of the drug research that is being done. They are also fi nancing the FDA. When you are buying research, you can bet that you can get what you want. They are using research, usually double blinded, to legitimize patent medicines which are promoted to be health promoting but are killing us by the thousands. The latest settlement that I am aware of was against Glaxosmithkline for three billion dollars in 2012. These companies are making so much money that they can afford to pay billions of dollars in fines to the gov ernment and continue to do business as usual. They consider it just another cost of doing business, but it is also a money making plan for both the drug companies and the government. This article was not intended to promote a moral or religious message; however, I feel inclined to conclude with the thought that if double blind studies are the only thing that you have left to believe in, may God save us all. A Breakthrough in Healthy Aging PhytoMulti The Smart Multi ® “ ” Defends cells from free radical damage and oxidative stress* Recharges cellular health* Nourishes cells with a complex array of phytonutrients* Activate Health Potential PhytoMulti is an entirely new class of daily foundation supplementation designed to help defy aging. 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Not all contents inside the capsule are vegetarian. † ‡ Breakthrough Science + Nutrigenomic Based Products + FirstLine Therapy ® + Unsurpassed Quality Metagenics = TheDifference ©2013 Metagenics, Inc. All Rights Reserved Dr. Harper goes further, addressing the same questions Dr. Feinberg and thousands of scientists are asking today about epigenetic control of the cell. Dr. Feinberg writes: 1) What is the gross reaction of the organism to changes in the environment? 2) What is the analysis of the simpler reaction of which the gross reaction is composed? 3) What is the assignment of each cell, its part in every reaction, and how is it controlled normally? In , Dr. William Harper wrote, “We might define health as controlled irritation of the nervous system that leads to adaptation; that is; some demand starts the process that causes innate to direct the impulses which control function for .”1 Andy Feinberg, MD, MPH, professor of molecular medicine and director for Epigenetics at Hopkins’ Institute for Basic Biomedical Sciences found reversible tagging of methylation patterns of genes respond to changes in the controlling the of the genes. Epigenetic scientists including Dr. Feinberg have determined that “ 2 Dr. Harper’s book was an explanation of chiropractic theory as promulgated by DD Palmer. The essence of Dr. Harper’s treatise resulted in a formula for chiropractic theory. It is important to remember Dr. Palmer was searching for the universal formula for disease when he “developed” chiropractic. Here is the formula for the chiropractic theory: Disease= Environment=Health Resistance When you study this formula in its entirety you will understand that this new science of epigenetics isn’t new at all. In fact, you will see that epigenetics explains what Drs. Harper and Palmer were communicating about health and disease, starting in 1895 and expanded in the 1960s. Dr. Harper called chiropractic the science of existence. This is no simple concept and requires serious study of every branch of science. There is a critical bit of information here. If missed, you will miss the entire concept of this formula. Dr. Harper defined environment as: “The totality of influences acting upon the organism ” Internal is intracellular and external is extracellular matrix, according to Harper.1 SEPTEMBER 2013 “If we could answer the following questions for every system, organ, and cell in the body, there would be no questions that we could not answer.” Dr. Harper addressed these questions in 1964, minus current questions such as; does the attachment of the DNMT3A epigenome to the Cp6/DNA cause the gene to express a certain disease or condition? Dr. Harper said, “this knowledge would explain how and why every symptom or abnormal function occurs. This is diagnosis. This concept is peculiar to chiropractic. Let us use it, even if it means discarding ideologies that have no basis in fact.”1 Chiropractic theory adds another layer to the current theory of epigenetic control of the cell. Chiropractic theory states that this expression of the cell is coordinated through the nervous system. In fact, Dr. Harper defines the line itself between environment and resistance as the nervous system in the chiropractic formula.1 Epigenetics struggles with this and in some of the literature even calls it . Most of the epigenetic scientists drop the idea at this point for the fear of being associated with the untouchable idea of including theology in science. Epigenetics is the expression of the genes in response to the internal and external environment of the cell. This expression can be short term or long term, abnormal or normal, but it is in response to changes in the cell environment. This is a new concept in medicine and is taking the scientific world by storm. This is right out of Dr. Harper’s book explaining DD Palmers principles. It is becoming clear that the gene itself plays only a partial role in health and disease. It isn’t the controlling factor as current genetic theory holds. It is the epigenetic control of the gene that determines the expression of the gene. Cellular biologists and epigenetic geneticists understand that methylation of the gene is a key to epigenetic control. This control is a disease.”3 Dr. Harper, using DD Palmers ideas, theorized that these neurological reflections from an altered cellular environment, and the reaction of the cells to this abnormal environmental stress, resulted in the chiropractic subluxation complex. He even defined the nervous system as the mediator in his formula for disease and health. result of the cell responding to a changing environment of the body either macro, micro, internal or external. Dr. Harper elucidated bacterial, viral, chemical, physical, electrical, psychic factors that are responsible for abnormal cellular environments and that the nervous system reflects those changes physically in the body and the spine. He also postulated that the nervous system ultimately controls the reaction of the body to the abnormal cellular and extracellular environment and treatment of the nervous system is vitally important. He didn’t know about epigenomes, histones, and methylation of genes and other new discoveries that control the cell’s reaction to its environment but I would imagine he would be very excited to read the new research. Dr. Harper, in light of this new information, might say that any stress; chemical, structural, or electrical, can result in the changing of the cellular environment; resulting in epigenetic control changes in the expression of the genes. Which, in turn, is reflected through the nervous system and may manifest in a biomechanical alteration of the body. The scientific world has arrived in 2013. Chiropractic started in 1895. Today’s modern theory of disease is Chiropractic 101, right out of Dr. David Harpers textbook, explaining DD Palmers theory of chiropractic. Today, we know about endocrine disruptors, receptor disruptors, genetically altered foods and micro dose chemicals, xenobiotics and drugs that change cellular environment causing an abnormal expression of the genes and disease. Chiropractic theory states, any physical, chemical, psychic factor that causes irritation of the nervous system results in functional pathology. 1) A recent study in stated, “It is becoming clear that all complex diseases are the result of geneenvironment interactions and that epigenetic modification of gene function during critical periods in development plays a critical role in the etiology of 2) 3) Harper, William David. ; Seabrook, TX: Texas Chiropractic College, 1974. Science News, , Sept. 16, 2012, page 1. , Seabrook, TX: Texas Chiropractic College 102 (2) (2008), pp. 7681. Board testing for the DABCI Diplomate Degree is scheduled for October 1920, 2013 and April 2627, 2014 Spring 2006 SEPTEMBER 2013 INNOVATIVE ALLERGY AND IMMUNOLOGY SERVICES Toward Better Health… » Inhalant Allergy » Food Sensitivity » Candidiasis » Intestinal Bacteria » Celiac Disease Profile » Wellness Programs Complimentary Courier Services via Federal Express 74 Accord Park Drive • Norwell, MA 02061 800-225-5404 foodallergy.com © 2013 Alletess Medical Laboratory, Inc. *Every attempt is made to offer these seminars as publicized; however, we reserve the right to adjust seminar locations, dates, times, etc. due to circumstances beyond our control. Program continuation is contingent upon adequate attendance. No audio or video tape recorders are allowed, and no portion of the seminar may be reproduced in any man ner without expressed written consent. Preregistration is required. ProHealth Seminars shall not be held responsible for any expenses incurred by registrar if a program must be altered and/or cancelled. Seminar fee is nonrefundable. Credit cards will not be billed until we have the minimum number of attendees (20). If the Doctor is unable to attend after preregistering and payment has been received, the seminar fee will be transferred to another Seminar (attended within 12 months of the original seminar) for an administration fee of $25. Any seminar fee not transferred and used within 12 months will be forfeited. *Every attempt is made to offer these seminars as publicized; however, we reserve the right to adjust seminar locations, dates, times, etc. due to circumstances beyond our control. Program continuation is contingent upon adequate attendance. No audio or video tape recorders are allowed, and no portion of the seminar may be reproduced in any man ner without expressed written consent. Preregistration is required. Pro Health Seminars shall not be held responsible for any expenses incurred by registrar if a program must be altered and/or cancelled. Seminar fee is nonrefundable. Credit cards will not be billed until we have the minimum number of attendees (20). If the Doctor is unable to attend after preregistering and payment has been received, the seminar fee will be transferred to another Seminar (attended within 12 months of the original seminar) for an administration fee of $25. Any seminar fee not transferred and used within 12 months will be forfeited. NEW HORMONE CREAMS from Professional Health Products ® Transdermal Timed Release Liposome Technology delivers active componentsdirectly into the bloodstream from a premeasured pump dispensor. Pro Femme Support Cream Natural Phyto Estrogen and Progesterone for aiding Hormonal Balance • Mood Swings • Weight Control • Fluid Regulation • Insomnia • Low Energy • Libido • Hair Loss • Hot Flashes • Headaches Pro Soothe Stress Cream Maca Extract, Glutamine, 7-Keto DHEA, Pregnenolone Formula compliments Pro Femme Support Cream • Supports Adrenal gland • Aids in Cortisol production when stressed • Allows Progesterone levels to build to optimal levels • Balances “Estrogen dominance” • Assists replenishing adrenal sex hormone reserves NUTRITIONAL SPECIALTIES East of the Mississippi plus Hawaii, Alaska and International - 800-245-1313 PROFESSIONAL HEALTH PRODUCTS, SOUTHWEST West of the Mississippi - 800-955-1769 Please call for your FREE educational CD : It is becoming more evident that hormone balance is not only vital to a healthy lifestyle, but necessary for health, vitality and longevity. Men and women alike suffer from hormone imbalances now more than ever, due to stress, environment, poor diet, toxins and life style choices. As a health care provider, it is necessary to understand how hormones affect the health of the patient and their quality of life. “Estrogen dominance,” which is another term for progesterone deficiency (coined by the late Dr. John Lee (MD)),1 is very common. Progesterone deficiency is not only due to excess exposure to estrogenic sub stances like xenoestrogens, but due to long term stress and its effect on the adrenals, which is compounded by the body’s inability to rid itself of excess hormones. Stress can be either emotional or physiological; pain, lack of sleep, blood sugar imbalances, digestive weak ness and toxins. In women, progesterone deficiency is a key factor in PMS management and menopausal symptoms, as well as, estrogen receptor positive (ER+) breast cancers. Typically, allopathic medicine leans on synthetic hormones to manage symptoms related to hormone imbalances. Synthetic hormones such as birth control or synthetic hormone replacement therapy (HRT) are not readily excreted from the body as natural hormones should be. This can cause long term estrogen domi nance, and/or exacerbate existing symptoms of mood, weight, sleep or menstrual irregularity.2 SEPTEMBER 2013 Balance is the key to hormonal health. Estrogen recep tors can become less sensitive when progesterone is low for long periods of time. Supplementing with natu ral progesterone balances the ratio of estrogen to progesterone and increases the sensitivity of estrogen receptors. 1 In conclusion, this study shows that topical trans dermal progesterone therapy does raise progesterone levels in the body and can be a viable way to relieve symptoms of PMS and menopause without the danger ous side effects reported from utilizing synthetic hor mone replacement therapy or birth control. This clinical study was performed to determine the effectiveness of a natural transdermal progesterone cream in raising progesterone levels in women between the ages of 3555, who are either perimenopausal or full menopausal. Participants were not involved in any other health regimens, nor were they under the care of any physician or had consumed hormone supplements or prescriptions in the last 6 months. Each participant submitted a saliva sample before and after the study to confirm progesterone levels at that time. Symptom questionnaires and vitals were collected every two weeks for the majority of participants, with a couple who only provided a before and after symptom ques tionnaire. Only the before and after symptom question naires were used for chart two on page 123. The supplements used for this study were provided by Professional Health Products (PHP) and are; Transder mal PRO SOOTHE STRESS ADRENAL SUPPORT CREAM with the ingredients: Water, Maca Extract, Glycerine, Octyl Salyclate, Glycerol Monolaurate, Glycerol Stearate/PEG 100, Cetearyl, Alcohol/Cocoa Glucoside, Caprillic Triglyceride, Safflower Oil, Puri fied Lecithin, 7Keto DHEA, DiIndolylmethane, Thioc tic Acid, Vitamin E, Glutamine, Pregnenolone, Cellu lose Gum, Peg 30, Glycerol Cocoate Phenoxyethanol, and Methisothiazolinone. This cream aims to balance the adrenal glands and provide ingredients to support the adrenals as they produce cortisol so as not to con vert progesterone to cortisol. The progesterone cream used was the Transdermal PRO FEMME SUPPORT + FEMALE SUPPORT CREAM with the ingredients: Water, Wild Yam Ex tract, Black Cohosh Extract, Glycerine, Octyl Salyclate, Glycerol Monolaurate, Glucerol Stearate/PEG 100, Cetearyl Alcohol/Cocoa Glucoside, Progesterone, Capryllic/Capric Tryglyceride, Dafflower Oil, 7Keto DHEA, Purified Lecithin, Evening Primrose Oil. DI Indolylmethane, Cellulose Gum, PEG30 Glyceryl Co coate, Phenoxyethanol, Methisothiazolinone. This cream was used to raise natural progesterone levels in the body. Dosage was one metered pump AM and one metered pump PM of Pro Femme Support + Female Support and one metered pump AM of Pro Soothe Stress Adrenal Support each day for about 56 weeks or until the Pro Femme cream was gone. When addressing female hormone levels it is important to consider the reason(s) for imbalance. Even women who do not display troublesome symptoms may experi ence symptoms which a well trained health provider can detect. Patients with liver congestion, poor sugar management, high stress, etc., are candidates for hor mone imbalances and conditions such as; PCOS, weight gain, memory problems, migraines and other symptoms (which many people assume are “normal”) can be related to hormone imbalance as well. Adequate progesterone is necessary for regular menses, preg nancy, regulating PMS, fat burning, reducing water retention, and protecting against certain female–related cancers as well as preventing the conversion of testos terone to DHT (dihydrotesterone), which prevents acne, facial and body hair, thinning of the hair and oily skin. Proper levels of progesterone also ease the transition into menopause, and reduce the symptoms that many American women experience. Menopause is not typi cally as serious of a condition for women in other coun tries where processed foods and a high stress lifestyle are not as common. In times of stress, the adrenals “steal” progesterone to make additional cortisol.3,4 In a perfect world, addi tional cortisol is only needed to get through a period of stress, but in our highstress world many people never get through the short burst of stress. It becomes a con stant part of their lives which depletes progesterone long term. Treating low progesterone without address ing adrenal insufficiency can be very difficult. In order to raise progesterone, the adrenal issue must also be addressed. This may include lifestyle modifications and overall health evaluation. See for more infor mation on these pathways.3 During this study each participant was provided with an adrenal support cream as well as a natural progesterone cream to support the adrenals and aid in raising proges terone levels. When taken in tablet form, any supplement (including natural progesterone) is often not fully absorbed due to a less than efficient digestive system. Topical creams are a more reliable option and allow progesterone and other nutrients to be delivered directly to the blood stream, bypassing the digestive system. Many topical creams require the patient to apply them to fatty areas and to rotate the area of application daily to avoid build up in the tissues. Build up over time will drastically reduce the effectiveness of the cream, which will allow the “estrogen dominance” symptoms to return, because excess progesterone produces the same symptoms as too little progesterone. This is due to progesterone receptor sites becoming “numb” to the hormone, which is similar to the body’s response with insulin resistance. It is not necessary to rotate a true transdermal cream that uses a liposomal delivery system because it does not build up in the tissue. These creams are applied to thin skinned areas and require no rotation.5 For this study, women were advised to collect the final saliva sample 36 hours after the last dose of cream. Due to the nature of this study other health concerns were not factored in. It is unknown which of these women suffered adrenal insufficiency or had other health con cerns that may have contributed to their final results. The goal of the study was to prove the liposomal deliv ery of topical progesterone would raise progesterone in this particular group of women. Saliva testing was utilized in this study because proges terone is readily measured by saliva testing. Serum levels of progesterone are not bioavailable, therefore serum testing is not accurate for this purpose.6 Healthy levels of progesterone measured as pg/ml are 300500 in saliva, but during supplementation due to the necessity to saturate the tissues with the proper amount of progesterone, levels above that are accept able. Variation of progesterone in the body is typically well tolerated up to 1500 pg/ml.6 Based on the saliva results we did find that progester one levels were raised in all of the women who partici pated. Some were small increases and others were much more dramatic. This suggests that the overall health of the individual is a factor and should be taken Spring 2006 SEPTEMBER 2013 Join PCS for Great Service and Major Savings on Hundreds of Lab Tests - Additionally - Soren BioStation™ EHR at No Cost and Online Ordering Capability In 2001 we leveled the playing field so that every appropriately licensed practitioner in America could have access to inexpensive lab testing! Want more information on lab interpretation & therapies? See our website for a special offer by Dr. Alex Vasquez, D.C., N.D., D.O. ® P: 866-999-4041 F: 866-999-9175 www.ProfessionalCo-op.com See Our Website for Testimonials! NO FEES, NO MINIMUMS. EVER. Professional Co-op does not have financial relationships, ownership or control of supplement or drug companies. Part Of The Healthcare Solution into consideration when creating an individualized pro gram. (See Chart 1: page 123.) Of the 13 participants who completed the study, 4 of them were still cycling, 9 were menopausal and 4 of those reported surgically induced menopause. Out of the 13 participants; 5 participants showed an im provement in hot flashes, 1 noted no hot flashes prior to the study, 6 noted an improvement in insomnia, with two stating they had no trouble sleeping prior, 7 showed an improvement in energy, night sweats and libido with 2 showing none of those symptoms prior, and with 5 stating no night sweats prior to the study, 8 participants showed an improvement in depression and fluid reten tion, with 2 stating they had no previous symptoms of depression and 4 stating that fluid retention was not a problem, 9 showed an improvement in anxiety with one stating no anxiety prior to the study, and 11 stated that their mind raced less, with one person stating she had no mind racing issues previously. Over half of the participants showed an improvement of 25% or more in all symptoms recorded except hot Spring 2006 flashes and 5 of them reported an improvement. This study shows that all women who participated experi enced some increase in progesterone by saliva testing. (See Chart 2: page 123.) 1) Lee, John. (2004) 2) Cutillo, Dawn M. . (2012) Print. p. 2627 3) William G Timmins , (2011) p. 49 4) Hormones and Chronic Stress Web; http://biohealthlab.com/testmenu/ hormones/hormonesandchronicstress/ 8/2013 5) Cutillo, Dawn M. .(2012) Print. p. 158 6) Saliva vs. Serum or Plasma Testing for Progester one Web w w w . j o h n l e e m d . c o m/ s t o r e / saliva_serum.html#absorb 8/2013 SEPTEMBER 2013 Chart 1 EƵŵďĞƌŽĨWĂƌƚŝĐŝƉĂŶƚƐtŚŽ^Ăǁ/ŵƉƌŽǀĞŵĞŶƚ ĂŶĚWĞƌĐĞŶƚĂŐĞŽĨ/ŵƉƌŽǀĞŵĞŶƚ;ϭϯWĂƌƚŝĐŝƉĂŶƚƐͿ ϴ ϳ ϲ ϱ ϰ ϯ Ϯ ϭ Ϭ ŶdžŝĞƚLJ ĞƉƌĞƐƐŝŽŶ DŝŶĚZĂĐĞƐ EŽ^LJŵƉƚŽŵƐ &ůƵŝĚ >ŽǁŶĞƌŐLJ ZĞƚĞŶƚŝŽŶ Ϯϱй/ŵƉƌŽǀĞŵĞŶƚ EŝŐŚƚ ,Žƚ&ůĂƐŚĞƐ /ŶƐŽŵŶŝĂ ^ǁĞĂƚƐ ϱϬй/ŵƉƌŽǀĞŵĞŶƚ >ŝďŝĚŽ ϳϱй/ŵƉƌŽǀĞŵĞŶƚ 2 Chart Before and After Progesterone Level SEPTEMBER 2013 , DC The most powerful cancer fighter ever discovered is naturally occurring vitamin D. The proof is in black and white: sometimes free substance like vitamin D could reduce national cancer rates by 75 percent. This is a shame, but doesn’t surprise me… Our leaders in medicine have sought to make us a nation dependent on drugs and sought to suppress natural solutions even if proven to actually work. Wow! That should make you just as mad as it makes me! Aside from cancer prevention, vitamin D cools the fire of inflammation throughout the body. Less inflammation means stronger, painfree joints and a healthier heart. Vitamin D also: Enhances mood Boosts your immune system Prevents bone and muscle weakness Dramatically lowers risk of heart disease Prevents diabetes Fights arthritis, pain and inflammation Helps prevent Parkinson’s disease and multiple sclerosis What’s astonishing is that the power of this simple nutrient has been in plain sight for years. Study after study has proven just how vital vitamin D is in combating a host of ailments. Yet the good news still hasn’t spread. It’s time to boost your vitamin D. The easiest, safest and cheapest way (it’s free) is to increase the amount of vitamin D the body produces through regular exposure to sunlight. However, depending where a patient lives, this is not always possible. In that case, you can also take vitamin D as a supplement. I recommend 5,000 IU every day. Don’t rely on your multivitamin to give you all the vitamin D you need, even if it does have D3. It’s a good start, but most still only have around 400 IU. Dr. Elena M. Morreale, DC, is a Doctor of Chiropractic and a Bioenergetic Practitioner. She has been in practice in Tampa, Florida since 1997. Graduating from the State University at Buffalo, New York in 1990 with a B.S. degree in Medical Technology. She worked at Mt. St. Mary’s Hospital in Lewiston, New York from 19881993 as a Medical Technologist doing laboratory and pathology analysis and diagnosis on blood, urine, stool and body tissues. She is a skilled practitioner with advanced EAV/EDS training in Bio energetics which represents a new science able to generate greater diagnostic and treatment pre cision. She has taken numerous classes in Holistic In fact, the Canadian Cancer Society contends that a simple supplement of 1,000 international units of vitamin D per day can reduce the risk of various cancers by as much as 60 percent. This is one of the most important findings in modern medical history: Vitamin D is the best current hope for preventing cancer. Period. So why don’t we hear more about this stunningly important news? Modern medicine seems to have no interest in natural treatments and preventions for cancer. Our FDA is more intent on prosecuting doctors who stray from drug treatments than disseminating the truth about natural cures. Even when a simple, and Spring 2006 SEPTEMBER 2013 Medicines such as bioenergetics, homeopathy, herbals, nutritional supplementation, energy work, emotional stress integration and muscle testing. She has combined chiropractic care, nutritional supple mentation and homeopathy for a complete holistic health care practice. Her main goal is to find the underlying cause of her patients problem and to tailor an individual treatment plan. Dr. Morreale brings the latest in alternative therapies with long lasting solutions for health and longevity. She focuses on helping people to heal themselves and regain their health. 1) OrdóñezMena J, Schöttker B, Haug U, Müller H, Köhrle Ortho Biotic J, Schomburg L, Holleczek B, Brenner H. "Serum 25 hydroxyvitamin D and cancer risk in older adults: results from a large german prospective cohort study." 2013 May;22(5):90516. 2) Grant, W.B. et al, “The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in ageadjusted cancer mortality rates,” 2006; 26:26872700 3) Lappe, J.M., et al, “Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial,” June 2007;85 (6):158691 4) Tuohimaa, P., et al, “Does solar exposure, as indicated by the nonmelanoma skin cancers, protect from solid cancers: vitamin D as a possible explanation,” July 2007;43(11):170112 Do Your Patients Have the Ortho Biotic Advantage? • High Concentration: 20 Billion CFU per Capsule • Predictable Results: Guaranteed Potency at Expiration • Improved Patient Compliance: No Refrigeration Needed VISIT US ONLINE FOR FULL PRODUCT DETAILS Ortho Biotic is manufactured by Ortho Molecular Products, a leading manufacturer in the professional supplement industry for over 20 years. OrthoMolecularProducts.com SEPTEMBER 2013 A continually contracting muscle requires specific nutrients and oxygen to sustain continued use. A lack of nutrient supply to a muscle tendon region will lead to overuse sports injuries. Therefore, let’s ensure that athletes get a healthy nutrient supply to the body through proper diet and supplementation that will assist the body with its natural function and repair processes. My take on why we should use supplementation is to aid in the healing of sports injuries. We need a simple and effective way to educate athletes on the importance of approaching their healthy process in 3 distinct phases: – Acute phase first 72 hours of injury – Subacute (healing phase) – day 4 through 8 weeks – Wellness/prevention phase The symptoms in the acute phase include acute muscle/ joint pain, and sprain/injury due to trauma or repetitive motion. There will be visual swelling, inflammation and spasm in the surrounding tissues. Additionally, there will be a loss of, or decreased, function. The objective of supplementation should be to aid in managing pain, reducing swelling, relax tight muscles, and use rehab strategies to restore motion. Nutrients to address swelling – trypsin, chymotrypsin, bromelain, which are proteolytic enzymes known to reduce swelling and aid in pain and inflammation reduction. These enzymes must be consumed on an empty stomach for full effectiveness. Ginger, turmeric, and boswelia are found to provide relief to pain and inflammation without causing any sideeffects to the athlete’s stomach. Calcium and magnesium are great additions to address muscle tissue. Calcium works to relieve spasms, and magnesium promotes muscle relaxation. Normally, to is in a 2:1 ratio. However, for muscle injury, consume to in a 2:1 ratio. Spring 2006 include continued joint or muscle pain, visual inflammation surrounding the injured area may still be present, and range of motion may still be compromised. Tissue repair and remodeling occurs in this phase! The objective of supplementation should be to initiate softtissue support by modulating the enzymes matrix matelloproteinases, help promote repair, and remodeling of connective tissue in the injured area. Matrix metalloproteinases (MMPs) are our own enzymes that are released at the time of injury. Unfortunately, excessive release of MMPs can damage healthy tendon collagen and connective tissue in the injured area. This excessive release aids in the degradation of healthy tissues. Therefore, if we modulate the expression of these enzymes we are able to support healthy remodeling of the connective tissue in the area. Thiaa (which is a selective kinase response modulator from certain plantbased components that positively influences numerous aspects of good health), berberine, selenium and folic acid are nutrients that impact matrix metalloproteinases. To support the growth and construction of connective tissues, the following nutrients are suggested – glycine, proline, lysine, vitamin C, B6, B5, Ltaurine, and silica. I would recommend glucosamine and chondroitin sulfate with MSM to aid in joint stability. are to achieve optimal tissue remodeling and support wellness/prevention, also to reduce the risk of reinjury and degeneration by installing what I call my foundation nutrition: 1) Phytomulti – multivitamin/mineral complex with additional phytonutrients 2) Omega3 fatty acids – to aid in the reduction of inflammation (2 grams of EPA/DHA) 3) Vitamin D aids in the healing of sports injuries (2000 IU and up) 4) Probiotics (Lacidophilus), which helps balance immune function (approximately 15 live organisms) 5) A phytonutrient green drink to help quench damaging free radicals “Somewhere, someone’s in training. And when you meet him he will beat you” (Navy seals mantra). A concussion is a traumatic brain injury that may result in a bad headache, altered levels of alertness, or unconsciousness. It temporarily interferes with the way your brain works. Concussions are on the rise in high SEPTEMBER 2013 school sports, and it can occur in any sport or reaction activities. So, all coaches and parents need to have an athlete evaluated when they have any kind of blow to the head. 1) Continue with natural antiinflammatory 2) Continue with magnesium 3) Acetyl1carnitine: helps with brain function The first priority nutritionally would be to help heal the current injury – in this case, the part of the brain injured by the concussion. By speeding the healing process, the overall pain and the duration of pain is reduced, thereby lessening the amount of substance P (associated with inflammatory process and pain) released within the thalamus of the brain. And also to decrease the activation of the brain’s immune cells, which are the source of inflammatory cytokines. DHA, Zinc, Turmeric Using these nutrition and nutritional supplements during healing is going to enhance the healing response and attempt to prevent adverse changes in the brain. Reviewed studies reveal that the speedy intake of the below macro and micro nutrients should be made common practice “almost immediately” – both right after a concussion and for two weeks following the concussion. 1) Protein: Helps heel the injury. Take 1g/kg of body weight, starting within a day of the injury 2) Creatine: Helps give the brain an intense and immediate hit of energy needed to help cells heal right after an injury 3) Reducing inflammatory damage to the brain: a) DHA: an omega 3 fish oil, which is an essential brain lipid that is critical for maximal brain health and protection b) Grape seed extract, bromelain, quercetin, ginger c) Polyphenols – turmeric, resveratrol 4) Antioxidants – alpha lipoic acid: Protects both the fatty and water soluble part of the cells 5) Choline: Critical for brain development 6) Vitamin D: All the known benefits, and now considered neuroprotective as well 7) Zinc: Enzyme for central nervous system (CNS) health. The brain is a part of the CNS. 8) Magnesium: One of the best weapons against delayed brain injury. Magnesium is one of these incredible elements that play a role in a number of biological processes. It is a cofactor in over 300 metabolic reactions, reduces inflammation, and elevates glutathione in cells (the cell’s major antioxidant). Low magnesium in the brain has also been shown to greatly increase the vulnerability of the brain to injury. If symptoms persist past a reasonable amount of healing time, then it is likely the brain (thalamus) is struggling. This means the ratio of substance P to BDNF (Brain Derived Neurotrophic Factor) is off. Substance P is in excess and there is not enough BBNF. SEPTEMBER 2013 A New York state concussion bill was signed on September 2011. The legislation will prevent students from returning to play until they have been without symptoms for at least one day and have been cleared by a physician. Ascocid 1000 (Time-Disintegrating Vitamin C) LYC 2000 (Buffered Vitamin C with 2000 MG of Fine Meshed Lysine) Cal & Mag Chelated Caps (Fast-Dissolving Calcium and Magnesium Capsules) Cal-C Caps and Cal-Cee Tablets (Calcium Citrate Supplements) Extress Super (B-Complex 50s Formulation) Lipo-Key (A Combination Formulation for Liver Support) Methyl-B12 Plus Oral Drops (Methyl B12 with Folic Acid and B6 - Homocysteine) Monolaurin 600 & 300 (Used to Retard Viral Invasion of the Body and Seasonal Allergies) Opti-Plus (Used for Healthy Eyes and Macular Degeneration) Samolinic (Norwegian Cold Water Salmon Oil with DHA and EPA) Division of Ohlsen Parmacal Company P.O. Box 220370, St. Louis, MO 63122 Please visit our website for details and complete descriptions on all of our fine, natural products. www.thekeycompanyusa.com Phone Orders: 800-325-9592 - 314-965-6699 This is the first in a series of articles that will take a detailed look at the GMO issue otherwise known as genetically modified organisms. Political and health impacts of genetically modified foods or GMfoods, will be explored in detail throughout this series. In all, I anticipate that I will answer approximately 100 questions on this topic. These articles represent my first draft writings that, after continued development and expansion, will appear in my upcoming book scheduled for release in November 2013 entitled, I think that it is appropriate to say that the GMO issue will be around for a long, long time. Not all of the evidence is in supporting either the safety or potential dangers of GMfoods. I will say however, that I do not believe that there is sufficient evidence to have placed GMfoods on the market at this time. I will also go so far as to say that I do not believe that GMfoods are safe. I based my decision on extensive research into both the political and scientific aspects of the GM issue. Over the course of my continued articles you will be left to make your own decisions. Maintaining an open mind when reading my articles, or exploring any other controversial topic that health care providers are faced with, is not only crucial, but absolutely necessary for objective, scientific exploration and advancement. The term, “genetically modified organism” refers to an organism whose genetic material has been modified due to genetic engineering techniques. GM technologies are generally used to alter the makeup of organisms such as animals, plants, or bacteria. GMO’s are the source of many modified foods and are used widely in scientific research to produce other goods as well. In 2006, specific countries that grew 97% of the global crops with transgenic genes were the United SEPTEMBER 2013 States (53%), Argentina (17%), Brazil (11%), Canada (6%), India (4%), China (3%), Paraguay (2%), and South Africa (1%). Within the next decade researchers expect to see a drastic increase in the use of GMOs and GM technologies in industrialized nations. You might find it incredible to learn that limited studies have been done demonstrating the safety of GM food consumption by humans, and several of those studies that have been conducted have shown serious health problems including increased cancer risk, fertility issues, inflammation in the intestines and other potential health issues. Monsanto Company, an American multinational agricultural biotechnology corporation headquartered in Missouri, is a leading producer of genetically engineered seed. The company, founded in 1901 by John Francis Queeny, operated primarily as a major producer of plastics, including polystyrene and synthetic fibers. As a chemical company, notable achievements by Monsanto and its scientists included being the first company to massproduce LEDs as well as performing breakthrough research on catalytic asymmetric hydrogenation. Multiple products manufactured by the company deemed controversial include insecticide DDT, PCBs (dielectric and coolant fluids), and Agent Orange. Monsanto Company has not been known for its honesty or transparency. A major lie of Monsanto Company was that the safety and benefits of the ingredients in GMOs were well established. In fact, no longterm studies about either the safety or benefits of GMO ingredients exist. The US Food and Drug Administration do not currently require safety studies of GMOs. Some independent studies currently going on also raise questions as to allergies and other health risks that could result from the consumption of genetically modified food products. In 1983, Monsanto, along with three academic teams, were among the first to genetically modify a plant cell, as well as conduct field trials of genetically modified crops. The first genetically modified food was the tomato. Between 1997 and 2002 the company came to focus heavily on biotechnology after a process of mergers and spinoffs that specified the company. Monsanto pioneered the biotechnology industry by applying its business model to agriculture. A “March Against Monsanto” movement began earlier this year to demonstrate in protest against GMOs and US chemical giant Monsanto. Monsanto claims that there are no dangers to the consumption of GMfoods by people, but my articles will prove otherwise. There are eight main steps involved in the development of GM crops. Firstly, the gene of interest is isolated. It is necessary to have existing knowledge about the structure, location, and/or function of a gene on a chromosome in order to identify the specific gene responsible for a desired trait in an organism. Some desired traits for GMO plants include tolerance to drought or resistance to insects. After isolating the gene, it is inserted into a transfer vector. Most commonly, a plasmid, or circular model of DNA, is used to transfer the isolated gene from the naturally occurring soil bacterium. Using rDNA, the gene of interest is inserted into the plasmid. The modified cell containing the plasmid and the new gene is combined with cells from the original plant, and some of the cells take up the plasmid containing the transfer DNA. After transformation, genes responsible for resistance are inserted into the plasmid and are transferred along with the genes containing the desired traits. When the cells are exposed to an antibiotic, herbicide, etc., only the cells that were transformed survive. The transformed cells can then be regenerated to form entire plants by culturing tissue. After GMO plants are grown, tests are performed to determine the number of copies of the gene inserted, whether or not the copies are intact, and whether or not the gene is functional. Assessments of the food and environmental safety of the GMOs are also conducted in conjunction with testing of plant performance. There are concerns that GMfoods may cause antibiotic resistance in people who consume the GM pesticide containing foods. Other concerns involve contamination of the environment with GMDNA (genetic material), increased risk of various diseases including cancer and gastrointestinal disease and autoimmune health problems. Subsequent articles in this series will be presented in this identical question and answer format. Stay tuned for much, much more on this controversial topic. Dr. Michael Wald, nicknamed the Blood Detective for his advanced clinical abilities and technological developments, holds degrees as a doubleboard certified nutritionist, a Certified DieticianNutritionist, a Certified Nutritional Specialist and is a doctor of chiropractic and earned his medical degree (MD) for educational purposes from the University of Health Sciences School of Medicine, Antigua. He is the director of nutrition at Integrated Medicine of Mount Kisco, P.C. and has Spring 2006 authored several books, hundreds of articles and has provided continuing education for doctors across the United States and abroad. He developed the breakthrough software program for the nutritional interpretation of laboratory work, that has revolutionized clinical nutritional practice. He can be reached at: www.intmedny.com, www.blooddetective.com, www.zombiefoodbar.com or [email protected]. 1) http://www.ornl.gov/sci/techresources/Human_Genome/ elsi/gmfood.shtml 2) http://en.wikipedia.org/wiki/Monsanto 3) http://www.huffingtonpost.com/2013/05/25/march againstmonsantogmoprotest_n_3336627.html 4) http://www.nepadbiosafety.net/subjects/biotechnology/ processofdevelopinggeneticallymodifiedgmcrops 5) http://recipes.howstuffworks.com/5commongenetically modifiedfoods3.htm 6) http://shiftfrequency.com/comprehensivelistofgmo products/ 7) http://www.disabledworld.com/fitness/gmfoods.php 8) http://www.rumormillnews.com/cgibin/archive.cgi? read=44805 9) http://en.wikipedia.org/wiki/tgenetically modified food#Highly_processed_derivatives_containing_little_to _no_DNA_or_protein 10) http://www.globalresearch.ca/potentialhealthhazards ofgeneticallyengineeredfoods/8148 11) http://www.greenmedinfo.com/blog/alertgmocornand roundupcausedcancerandkilledrats 12) http://www.reuters.com/article/2012/09/19/usgmcrops safetyidUSBRE88I0L020120919 13) http://www.gmocompass.org/eng/grocery_shopping/ p r o cessed fo o d s/1 5 3 .ani mal feed ge ner ic engineering.html 14) http://www.ucsusa.org/food_and_agriculture/ourfailing foodsystem/industrialagriculture/theyeatwhatthe realityof.html 15) http://enhs.umn.edu/current/5103/gm/harmful.html 16) h t t p : / / e a r t h o p e n s o u r c e . o r g / f i l e s / p d f s / GMO_Myths_and_Truths/GMO Myths and Truths 1.3b.pdf 17) http://en.wikipedia.org/wiki/Intellectual_property 18) http://digital.law.washington.edu/dspacelaw/bitstream/ handle/1773.1/511/19PacRimL&PolyJ459010).pdf? sequence=3 19) http://www.biogeneticservices.com/dnagmo.htm 20) http://www.brainwaving.com/2010/07/28/genetically modifiedanimals/ 21) http://www.asil.org/insigh38.cfm 22) h t t p : / / w w w . b e t t e r h e a l t h . v i c . g o v . a u / b h c v 2 / bhcarticles.nsf/pages/Genetically_modified_foods 23) h t t p : / / a r t i c l e s . m e r c o l a . c o m / s i t e s / a r t i c l e s / archives/2004/01/24/gmfoods.aspx SEPTEMBER 2013 IODORAL® Lugol solution in tablet form Available in tablets of 12.5 mg packaged in bottles of 90 tablets and 180 tablets Now available also in tablets of 50 mg packaged in bottles of 30 and 90 tablets Based on the collective experience of U.S. physicians who used Lugol solution extensively in their practice for iodine supplementation over the past century, the recommended daily intake for iodine supplementation was 0.1 to 0.3 ml containing 12.5 to 37.5 mg elemental iodine (1-3). We recently confirmed the keen observation of our medical predecessors: this is exactly the range of iodine/iodide intake required for whole body sufficiency, based on a recently developed iodine/iodide loading test (3). For non obese subjects, whole body sufficiency for iodine can be achieved within 3 months with daily intake of 12.5 to 50 mg (4,5). 1) 2) 3) 4) 5) Abraham, G.E., Flechas, J.D., Hakala, J.C., Orthoiodosupplementation: Iodine sufficiency of the whole human body. The Original Internist, 9:30-41, 2002. Gennaro, A.R., Remington: The Science and Practice of Pharmacy, 19th Edition, 1995, Mack Publishing Co., 976 & 1267. Abraham, G.E., The safe and effective implementation of orthoiodosupplementation in medical practice. The Original Internist, 11:17-33, 2004. Abraham, G.E., The concept of orthoiodosupplementation and its clinical implications. The Original Internist, 11:29-38, 2004. Abraham, G.E., The historical background of the iodine project. The Original Internist, 12(2):57-66, 2005. For further information on: - ® IODORAL Reprints of relevant articles How to implement orthoiodosupplementation in your practice How to request kits for the iodine/iodide loading test Vist our website at www.optimox.com Or contact us at: OPTIMOX CORPORATION P.O. Box 3378 Torrance, CA 90510-3378 or Call Toll Free: (800) 223-1601 or Fax: (310) 618-8748 or Email: [email protected] : ( tremor, pallor, and perspiration. The migraine sufferer may experience different identifiable migraines (migraines that have no classification), and also experience the tension type headaches as well. The is characterized by an or a "warning" symptom that may range from a very few minutes to nearly an hour announcing the expected arrival of an oncoming headache. Most migraine sufferers report some sort of visual disturbance as their aura. Flashing lights, intermittent or zigzagging lines, a blind spot in the field of vision, and photophobia are commonly reported. Several sufferers also report a paresthesia or numbness. Vomiting may provide relief. Even if the patient does not vomit, most migraineurs report they think they would feel better if they could. The "National Migraine Foundation" reports that 70% of all migraine sufferers are women, and 65% occur around the menstrual cycle. Allergies are common contributors to migraines and should always be considered in addition to spinal subluxations. The most commonly cited suspected allergens include inhalants such as perfumes, tobacco smoke and petroleum products. Foods that are commonly reported for triggering migraines include, but are certainly not limited to, chocolate, alcohol, all dairy, several assorted nuts, beef, pork, caffeine, and fish. All preservatives including glutamate, aspartame, nitrates, monosodium and others should be suspect. Aspartame is often cited to trigger allergic reactions. : Several vitamin and mineral deficiencies have been reported to be associated with various Consider magnesium, B complex vitamins, Omega3 Fatty Acids, and tocopherols. Multichannel blood chemistries, CBC with differential, urinalysis, circulation studies, and xrays to the cervical and upper thoracic spine should all be considered. This type headache is characterized by severe pain (that may begin mild) localized unilaterally in the temporal region with localized scalp tenderness and signs of vascular inflammation. The pain may be greatly increased by laying down. Other symptoms may include depression, gastrointestinal, fever, and night sweats. If the inflammation is part of more widespread vascular disorders the pain may well be bilateral. The arteries most often affected are the superficial temporal, Spring 2006 vertebral, ophthalmic, and the posterior ciliary arteries. The internal and external and central retinal arteries are less frequently affected. As temporal arteritis progresses, red nodules may appear over the temporal regions. Palpable tenderness may only be elicited over the affected portion of the artery(ies). The affected portion of the vessel palpates hard, convoluted, and incompressible. Blindness can result if the blood vessels serving the optic nerve become involved. The symptoms of ophthalmic artery ischemia are reported to begin with diplopia or transient vision blurring especially upon awakening. At the onset, an ophthalmic examination may be normal but within two days papilledema, hemorrhages and exudates can develop. An elevated ESR typically above 4050 mm/hour and frequently above 90 mm/ hour. A negative ESR does not rule out temporal arteritis. Giant cell arteritis confirmed by biopsy of the affected artery provides the definitive diagnosis. Multichannel blood chemistries, CBC with differential, Doppler/plethysmography, and spirometry should be considered. Temporal arteritis is a cardiovascular condition and its underlying causes should be addressed. Drug induced headaches are referred to as rebound headaches and are a result of regular use of pain relieving medications. A truly vicious cycle usually begins ominously by pain relievers taken even as little as two to three days a week. Consequently, as soon as the medicine wears off, hypersensitive receptors, in susceptible individuals, turn on to produce a new headache. That leads the headache sufferer to take more medicine which in turn leads to more headaches. Before long, most rebound patients are taking headache medicine every day. Even overthecounter medications can lead to rebound headaches (as well as the stronger medications such as codeine, barbiturates and ergotamine) It is believed that too much pain medication alters the serotonin levels so the chemical loses its effectiveness. Be sure to look for allergic reactions. SEPTEMBER 2013 Me nt 10 ion C % Di DID sc 2 ou 013 nt Request a Free Sample | 888.328.9992 Freedom from digestive challenges. Digestive health is fundamental to general health.* Vital Nutrients offers a full range of products that support all aspects of gastrointestinal function from promoting a healthy intestinal lining, to enhancing nutrient absorption and supporting proper pH levels.* Made in the USA | FDA-Inspected Facility 888.328.9992 | vitalnutrients.net *This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Dr. P. Reginald Hug* Birmingham, AL Dr. David Mulholland Anchorage, AK Dr. Debra Carpenter Pueblo West, CO Dr. Cheryl Vincent Simsbury, CT Dr. Thomas Jensen Sterling, IL Dr. Lynn Betz Auburn, KS Dr. Terry Collinson Colorado Springs, CO Dr. John Findlay W. Palm Beach, FL Dr. Theodore Johnson Chicago, IL Dr. Ben Bowers Wichita, KS Dr. James McGinn, Jr. Crystal Lake, IL Dr. Richard Brown Olathe, KS Dr. Michelle Oliver Springfield, IL Dr. Susan BuchananCheney Phillipsburg, KS Dr. Anthony Pantanella Hoffman Estates, IL Dr. Ralph Cardin Overland Park, KS Dr. Michael Poierier Lombard, IL Dr. H.M. Chalker Meade, KS Dr. Robert Pyne, Jr. Palos Hills, IL Dr. Dustin Cheney Phillipsburg, KS Dr. William Shelton Lombard, IL Dr. Rodney Clements Eldorado, KS Dr. Douglas Stam Bourbonnais, IL Dr. Paul Hughes Edgerton, KS Dr. Melanie Tiahrt Alton, IL Dr. Tobi Jeurink Gardner, KS Dr. Steven Zaeske Orland Park, IL Dr. Katherine Kubovy Overland Park, KS Dr. Alex Zevan, III Bloomingdale, IL Dr. Christena Nicholson Overland Park, KS Dr. Stephen Boudro Elmhurst, IL Dr. John Bernzott Connersville, IN Dr. Janie Pirner Wichita, KS Dr. Shawn M. Breton Arlington Heights, IL Dr. Thomas Jansen Kendalville, IN Dr. Rhonda Button Carmi, IL Dr. William Lyden Mishawaka, IN Dr. Christine Cosgrove Roselle, IL Dr. Brian McGuckin Valparaiso, IN Dr. Stephanie Clay Baton Rouge, LA Dr. Sharon DeFrain Peotone, IL Dr. Robert Prather Indianapolis, IN Dr. Robert W. Smith Baton Rouge, LA Dr. Mete Durum Arlington Heights, IL Dr. Ramneek Bhogal Davenport, IA Dr. Wayne Sodano Bel Air, MD Dr. Gary Bowden McGregor, IA Dr. Nancy Bronstein Great Barrington, MA Dr. Rita Cummings Denver, CO Dr. Stan Throckmorton Anchorage, AK Dr. Paula Dechert Denver, CO Dr. Michael Cessna Tucson, AZ Dr. Jeffrey Gappa Brighton, CO Dr. Laura Frey Tucson, AZ Dr. Timothy Gerhart Glendale, AZ Dr. Kellie Gray Glendale, AZ Dr. Michael Stone Tucson, AZ Dr. Lance Clouse Van Buren, AR Dr. Michael Brunner Glendale, CA Dr. Lewis Holm Littleton, CO Dr. William Kleber Berthoud, CO Dr. Reiner Kremer Franktown, CO Dr. Steven Lokken Colorado Springs, CO Dr. Duane Lowe Colorado Springs, CO Dr. Brandon Lundell Longmont, CO Dr. David Paradiso Colorado Springs, CO Dr. Christine Cohn Newport Coast, CA Dr. Corrie Pillon Denver, CO Dr. Ai Lien Diep Los Angeles, CA Dr. Philip Pollock Sterling, CO Dr. Jan Dooley Arcata, CA Dr. Deborah Riekman Colorado Springs, CO Dr. Jeffrey Greene Los Angeles, CA Dr. Kimberly Schmidt Ft. Collins, CO Dr. Valerie Johnson Los Angeles, CA Dr. Christie Sonchar Colorado Springs, CO Dr. Jill Jordan Carlsbad, CA Dr. Thomas Turner Boulder, CO Dr. Andrew Lucas Riverside, CA Dr. Michael Vanaria Boulder, CO Dr. Kathleen Power Pasadena, CA Dr. Brian Wilson Englewood, CO Dr. Rowen Richardson Glendora, CA Dr. Gina Carucci Wethersfield, CT Dr. Scott Soluk Los Angeles, CA Dr. Sylvie Wellhausen Loma Linda, CA Dr. Kelly Worth Orange, CA Dr. Robert Arne Littleton, CO Dr. John Baer Englewood, CO * Retired DABCI Practitioner Dr. David Frerking Tavares, FL Dr. Marguerite Gerger Clearwater, FL Dr. Janice Piro Palm Harbor, FL Dr. Susan Player Clearwater, FL Dr. John Podlaski Ocala, FL Dr. Larry Haberski Stone Mountain, GA Dr. Uma Mulnick McCall, ID Dr. Delilah Anderson Sandwich, IL Dr. Jeffrey Bergin Lindenhurst, IL Dr. Rachael Fabbi St. Charles, IL Dr. Raymond Ferre Decatur, IL Dr. Mark Fredrick Gurnee, IL Dr. Suzanne Chester Simsbury, CT Dr. David Hepler Lincoln, IL Dr. Paul DiDomizio Wolcott, CT Dr. William Hogan Lombard, IL Dr. Ralph Manfredi New Fairfield, CT Dr. Lester Holze, Jr. Elgin, IL Dr. Mark Pappas West Haven, CT Dr. Cindy Howard Orland Park, IL Dr. Joanne Santiago Avon, CT Dr. Frederick Hult McHenry, IL Dr. Grant Iannelli Lombard, IL Dr. Darlene Ehlers Tipton, IA Dr. Robert Friedrichs Mason City, IA Dr. Alvin Schwerdtfager Lindsborg, KS Dr. Ron Young Salina, KS Dr. Daniel M. McGregor Prudenville, MI Dr. Tracy A. Stomgren Glenwood, IA Dr. Jeffrey Anderson Edina, MN Dr. Lynn Theesfield Ames, IA Dr. Robert Bergan Minneapolis, MN Dr. Zach Watkins Johnston, IA Dr. Timothy Bertsch Champlin, MN Dr. Anita Wubenna Parkview, IA Dr. Linda Bowers Bloomington, MN Dr. Mark Albers Wichita, KS Dr. Russell DesMarais St. Paul, MN Dr. Joel Eichers Chanhassen, MN Dr. Terry Nelson Independence, MO Dr. Sandrine Martin Cornelius, NC Dr. John Gerber Blaine, MN Dr. R Vincent Satterwhite Kansas City, MO Dr. Jacqueline McKool Rutherfordton, NC Dr. Timothy Gerhart Red Wing, MN Dr. Jeremy Thornton Stockton, MO Dr. Barbara Saunders Garner, NC Dr. Jedidiah Krauss St. Louis Park, MN Dr. Jeffrey S. Ware Lake St. Louis, MO Dr. Todd Smith WinstonSalem, NC Dr. Mac Beth Lindstrom Slayton, MN Dr. Robert Wiehe West Plains, MO Dr. Mark Yeager Charlotte, NC Dr. Todd McGillick Gaylord, MN Dr. Christopher Murray Hastings, NE Dr. Robert Gilbert Mansfield, OH Dr. Mallory Rupp Grand Island, NE Dr. Mark McAdoo Athens, OH Dr. Scott Sole Kearney, NE Dr. Van Merkle Dayton, OH Dr. Howard Balduc Las Vegas, NV Dr. Gerry Langston Tulsa, OK Dr. Craig Roles Henderson, NV Dr. Mark Mercer Mannford, OK Dr. Sandra Spore Stillwater, MN Dr. Jon Mastrobattista Bernardville, NJ Dr. Colleen Robinson Duncan, OK Dr. Leslie Stewart St. Paul, MN Dr. Perry Ricci Egg Harbor City, NJ Dr. Charles Strauman St. Louis Park, MN Dr. John Dalton Roswell, NM Dr. Thomas Miller Coon Rapids, MN Dr. Joseph Muldoon Slayton, MN Dr. Brenwyn Peddycoat White Bear Lake, MN Dr. Gregory Peterson Winona, MN Dr. Dane Roubos Bloomington, MN Dr. Terese Tomanek Duluth, MN Dr. Timothy Whelan New Hope, MN Dr. Jon Williams Bloomington, MN Dr. David Clark Oak Grove, MO Dr. Charles Eckert Raymore, MO Dr. Scott Hollis Blue Springs, MO Dr. Jay Kessinger Rolla, MO Dr. Darren Kirchner Kahoka, MO Dr. Kelley Kirchner Kahoka, MO Dr. Mable Leckrone Liberty, MO Dr. Duane Lowe Maplewood, MO Dr. John H. Gelhot Albuquerque, NM Dr. Shereen Jegtvig Albuquerque, NM Dr. Ronald Safko New York City, NY Dr. John Zilliox Amherst, NY Dr. Richard Santelli Bethany, OK Dr. Michael Taylor Tulsa, OK Dr. Daniel Beeson Portland, OR Dr. David Braman Tuelatin, OR Dr. Kathleen M. Galligan Oregon City, OR Dr. Edward M. Geller Medford, OR Dr. Usha Honeyman Corvallis, OR Dr. David Wickes Portland, OR Dr. Joe Lindley Houston, TX Dr. Bruce Fink Coudersport, PA Dr. Tim McCullough Houston, TX Dr. Mark Homison Cranberry Township, PA Dr. Karen L. Jorgensen Pittsburgh, PA Dr. John LaHoda Richboro, PA Dr. Fredrick Osterberg Red Lion, PA Dr. Jennifer Welch Westerly, RI Dr. Jon Bergrin Florence, SC Dr. Bruce Gwinnup Charleston, SC Dr. Peter Kfoury Charleston, SC Dr. Morgan Kutzner Greenville, SC Dr. Robert Pascal Charleston, SC Dr. Virginia Samuel Columbia, SC Dr. Roger Bommersbach Brookings, SD Dr. V.M. Thompsom Arlington, TX DR. Richard Allen Sandy, UT Dr. Don Vradenburg St. George, UT Dr. Robert Duca Dunn Loring, VA Dr. Guntrang Khalsa Herndon, VA Dr. H. Earl Moore Spokane, WA Dr. Michael Berglund Kenosha, WI Dr. Leslie Best Madison, WI Dr. Barbara Bradley Wausau, WI Dr. David Schwierert Rapid City, SD Dr. Bernie Finch Pepin, WI Dr. William Strauss Lebanon, TN Dr. Gwendolyn Gauerke Iola, WI Dr. Phillip Arnone Matthews, NC Dr. Kenzie Maloy Hermiston, OR Dr. Ralph Burton Kennedale, TX Dr. Stephen Button Mount Airy, NC Dr. Scott Northrup Brookings, OR Dr. Lance CarltonDurrett The Woodlands, TX Dr. Karen Carrick Raleigh, NC Dr. Kristopher Peterson Hermiston, OR Dr. Victor Carsrud Austin, TX Dr. Rick Davis Conover, NC Dr. Thomas Richards Beaverton, OR Dr. Janie Duke Plano, TX Dr. Nikolas R. Hedberg Asheville, NC Dr. James Siegel Canyonville, OR Dr. Steve Grimm San Antonio, TX Dr. Dean Kenny High Point, NC Dr. Mark Thomas Cottage Grove, OR Dr. Doreen LewisOverstrom San Antonio, TX Spring 2006 Dr. Mike Prioux Friendswood, TX Dr. Kevin Branham Eagle River, WI Dr. Steven Lumsden Gresham, OR Dr. Gregory Mrozinski Houston, TX Dr. Roger Prill Mitchell, SD Dr. Edward Brown Dallas, TX Dr. William R. Armstrong Laurenburg, NC Dr. Zachery McVey League City, TX Dr. Craig Gilbaugh Ashland, WI Dr. Kathleen Maedke Milwaukee, WI Dr. Cheryl Metzler Green Bay, WI Dr. Gina R. Schultz Blanchardville, WI Dr. David A. Sommerfield Rice Lake, WI Dr. Dean Willhite Manitowoc, WI Dr. Kelly G. Worth Racine, WI SEPTEMBER 2013 Build Your Business & Start Saving Doctor’s Choice is an international healthcare organization offering licensed healthcare professionals a one-stop shop solution for obtaining deep discounts on diagnostic laboratory services provided by some of the world’s best laboratories. Save up to 80% on Laboratory Testing We take the cumulative buying power of well over 1,000 healthcare professionals in our organization and continually negotiate the absolute lowest prices with our laboratory partners. These discounted prices are then passed on to our entire membership. Whether you have a low-volume or a highvolume practice, we are certain we can save you money. Increase Revenue with our Functional Health Reports The Doctor’s Choice Functional Health Report helps clarify health conditions in terms that are easy for the patient to understand. These wide-ranging reports add value to your practice by providing the patient with a take-home report analyzing their health. What is included in the report? SPECIAL PROMOTION Five FREE abbreviated reports and one FREE •Credible, evidence-based analysis comprehensive report for all of our members for you and your patients, making testing easier •Helping you clearly see through complex issues •Color-coded summaries, so you don’t miss anything important •Easy-to-understand language, so your patients aren’t intimidated or overwhelmed •Personalized health improvement plans, including what to avoid! •Progress tracking, so your patients can see their improvement •Supplement recommendations (generic or brand name) balances mical Im Bioche st Justa Te e: 62 Male / Ag asures lance" me Imba The "% To learn more, call: the lab how far % m the ult is fro res cy ce Imbalan Deficien -6% 63% tio A/G Ra -43% min se ata H Albu ph 227% ne Phos L Alkali 22% Gap H Anion 291% tio Ra e B.U.N. nin -32% N./Creati t U. B. H 0% phil Coun so Ba L 360% ils ph so Ba -25% in, Total H Bilirub -23% tio um Ra lci rus L Ca -117% /Phospho Calcium 48% ide L Chlor -50% rol ste H Chole -71% L CO2 16% ine tin L Crea unt 63% Co hil Eosinop 34% s hil op H Eosin 3 10% T39% H Free 4 Free T69% H GGT n 124% uli H Glob e -45% os ol H Gluc -37% ter holes L HDL-C rit 6% toc L Hema 10% bin Hemoglo 58% tal Iron, To 72% H LDH -29% L t LD un H 24% Co hocyte mp Ly L 6% cytes Lympho 113% MCH -50% H MCHC -8% V L MC 58% Count nocyte 1-888-852-2723 www.DoctorsChoice.net abetic) ete Alph (Compl middle erence of the ref Excess st : 1/1/20 Blood Te per Du Dr. Su te fo ee footno range. *S feren Lab Re Low Result 0.8 3.6 1.33 5.30 45.00 41.23 20.00 60.61 37.00 1.00 4.30 9.00 2.57 40.0 8. 7 6 90.00 258.00 21.00 0.33 333.00 9.00 390.00 1.40 45.00 4.00 124.0 33.0 40.0 15. 120 262 14 148 4 Subscribe to for only $50 annually Name _____________________________________________________________________________ Address ___________________________________________________________________________ City _________________________________________ State _________ Zip ___________________ Phone ______________________ Fax ______________________ Email ______________________ Check enclosed Bill my Visa/Master Card Bill my American Express Credit Card Number ____________________________________ Exp Date _________ CVD _______
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