Programme Specification GENERAL INFORMATION Awarding Institution//Body University of Bath Teaching Institution University of Bath Validated/Franchised (if appropriate) Programme accredited by (including date of accreditation) Royal Society of Chemistry August 2012 Programme approved by (including date & minute number of Senate) Final award Master of Science (MSc) Postgraduate Diploma Programme title MSc in Chemistry for Drug Discovery PG Diploma in Chemistry for Drug Discovery UCAS code (if applicable) N/A Subject Benchmark Statement N/A Intended level of completed programme (in line with FHEQ) M Duration of programme & mode of study MSc: One year, full-time. PG Diploma: Two semesters, full-time. Date of Specification preparation/revision 23 March 2011, 24.9.12, 7.1.2013 Applicable to cohorts (eg. for students commencing in September 2008 or 2008/09 – 2009/10) For students commencing in September 2016. Synopsis and academic coherence of programme The MSc in Chemistry for Drug Discovery is delivered by the Department of Chemistry, alongside the current MRes Chemistry programme. The MSc programme comprises a modular, 90-credit structure, delivered over a twosemester and summer research project timeframe. Students are required to take a mix of compulsory and optional units making-up a total of 30-credits worth of material per semester. Students complete their studies with a 30-credit MSc research project over the summer. The MSc programme is designed to give the student an insight into a range of research activities, techniques and chemical skills related to drug discovery as well as to widen their knowledge both of the subject itself and the context within which the research will take place. It will provide the student with an understanding of the role of drug discovery in economic development and the way in which science is managed. The graduate will have the potential to enrol on a PhD programme or to use this qualification in research or management. 1 Educational aims of the programme The programme has four main aims: To broaden knowledge of the conduct, management, implications and exploitation of chemical research related to drug discovery. To enhance the specialist knowledge of the students at the forefront of the discipline. To provide training in and experience of high level research by conducting a defined research project. To allow the student to gain a comprehensive understanding of research techniques relevant to their ultimate research goals Intended learning outcomes (including teaching, learning and assessment methods, specifying those applicable for interim awards where appropriate) The differences between Semesters 1 and 2 are in terms of breadth of knowledge, whilst the differences between the Diploma stage and Semester 3 is in the ability to undertake an independent research project. Teaching is through a combination of lecture-based material, practical work, seminars, individual study and a research project supervised by an academic member of staff. Knowledge & Understanding: Upon completion of Semester 1, the student will: have begun to acquire an in-depth knowledge of (Semesters 1 & 2 are common to the subject area. the PG Diploma and MSc. The have gained expertise in the chemical techniques research project in Semester 3 in required for a research project related to drug MSc-only). discovery. have gained practical experience in synthetic and measurement-based chemistry. Upon completion of Semester 2, the student will, in addition: have increased and broadened their in-depth knowledge of the subject area. have acquired the ability to write a critical review of a particular area of research. be prepared to undertake a research project. Upon completion of the MSc Programme of Study, the student will, in addition: have gained experience of carrying out a research project. be able to discuss the relevance of their research in the context of published work. have acquired in-depth knowledge of how research in chemistry adds to the body of knowledge. Teaching and learning methods: Lectures and guided reading Practical instruction by laboratory staff (academic staff, PGs, technicians and post-doctoral scientists) Preparation of a research project report 2 Attendance at seminars by external speakers Giving research presentations at research group level Assessment: Written, unseen examination of taught units, mainly at the Masters level. Masters level postgraduate training module assessed by examination, practical exercises and presentation. Advanced practical chemistry course assessed by written reports and viva voce examinations. Reviews of the current literature. In addition, in respect to the MSc, A written report based on the research project with a viva voce examination. Intellectual Skills: The student will be able to: solve problems related to the topics covered in the lecture courses define research problems and formulate questions and hypotheses be able to select appropriate strategies for research and/or demonstrate the nature of good experimental design where appropriate use specific data analysis methods and tools, including appropriate software solve problems in creative and innovative ways In addition, in respect to the MSc, the student will be able to: demonstrate in-depth knowledge of their research area suggest new hypotheses relevant to their research Teaching and learning methods: Lectures and guided reading Laboratory instruction by laboratory staff (PGs, technicians, post-doctoral scientists and supervisor) Attendance at seminars by external speakers Assessment: Written, unseen examination of taught units, mainly at the Masters level. Professional Practical Skills: In addition, in respect to the MSc, A written report based on the research project with a viva voce examination The student will be able to: understand Health and Safety legislation at an appropriate practitioner level and complete COSHH risk assessments 3 demonstrate competence in data manipulation, including instrumentational outputs and the analysis of numerical, graphical and textual data, as appropriate demonstrate good record keeping and lab-book methodology use computational modelling understand ethical and legal aspects in research write scientific abstracts, papers and reports In addition, in respect to the MSc, the student will be able to: employ a range of skills required to undertake effective research demonstrate competence in use of equipment relevant to the research project communicate results of research by presenting seminars and a poster Teaching and learning methods: Lectures and guided reading Laboratory instruction by laboratory staff (PGs, technicians, post-doctoral scientists and supervisor) Preparation of a written report Giving presentations at research group level Guided supervision by the project supervisor Assessment: Masters level postgraduate training module assessed by examination, practical exercises and presentation. Advanced practical chemistry course assessed by written reports and viva voce examinations. Practical skills assessed by observation in the laboratory In addition, in respect to the MSc, Laboratory and profession skills are assessed during the research project including a viva voce examination. Transferable/Key Skills: The student will be able to: demonstrate interpersonal skills and personal effectiveness of planning time management; writing up on time; handling relationships with supervisor, peers and support staff; planning a career including preparing a CV, and understanding fellowship and research opportunities show competence in the use of IT and information handling. This will include, where appropriate, use of databases, word processing, spreadsheets, statistics packages, making web pages, use of WWW and other electronic information sources. communicate effectively, with colleagues and a wider audience, using a variety of media. 4 Teaching and learning methods: Lectures and guided reading Courses run by the Staff Development Unit for postgraduates Laboratory instruction by laboratory staff (PGs, technicians, post-doctoral scientists and supervisor) Assessment: Presentations during unit assessments Masters level postgraduate training module assessed by examination, practical exercises and presentation. Advanced practical chemistry course assessed by written reports and viva voce examinations. Practical skills assessed by observation in the laboratory In addition, in respect to the MSc, Laboratory and profession skills are assessed during the research project including a viva voce examination. MSc Research Project: Learning Outcomes To apply high-level research in practice, by conducting a defined research project in a specialist subject related to drug discovery using a wide range of research techniques as appropriate for the particular project area. To demonstrate critical awareness of research literature related to the project area in order to place the research in context. To be able to identify the tasks to be completed in a research project proposal, plan a scheme of work, and complete the project to a professional standard in a manner commensurate with current safety legislation with minimal supervision and guidance. To demonstrate the successful completion of these tasks in a well-structured and coherently written dissertation commensurate with a chosen journal style, with the potential for publication. This will include a discussion of the background to the work, the research outcomes from the project, and future directions. To discuss and defend the conclusions drawn from the study in an oral examination. MSc Research Project: Assessment The research project is assessed by a written report and an oral presentation. The report is assessed by the supervisor and two assessors, and the student also examined viva voce by the assessors. In addition, the supervisor formally evaluates the laboratory work with respect to its effectiveness. Structure and content of the programme (including potential stopping off points) The PG Diploma and MSc programmes include a mix of taught units, professional training and training in research skills. Programme Content: Postgraduate training module Advanced group work in practical chemistry course Preparation for research project (6 credits) (6 credits) (12 credits) 5 One I-Level unit in Drug Properties 30 credits of M-level units in drug discovery topics Research project (5 days/week for Semester 3, MSc only) (6 credits) (30 credits) (30 credits) The choice of optional units is decided by the student with advice from the Director of Studies and the Personal Tutor. Students are required to attend the regular seminars given by external speakers, especially in topics related to their specialist area. For the MSc, project supervisors normally have a scheduled private meeting with their students each week, and most staff have weekly lab meetings, research focus meetings or 'problem solving' meetings for open discussion of scientific issues. Successful completion of the Semester 1 and Semester 2 material (60 credits) allows the student to graduate with a PG Diploma. Successful completion of this material plus the research project (30 credits) allows the student to graduate with a MSc. Details of work placements / work-based learning / industrial training / study abroad requirements None. Details of support available to students (e.g. induction programmes, programme information, resources) All laboratories in the department are purpose-designed and have been fitted out to a high standard. Postgraduate workrooms have PCs and on-line access to the library catalogue, electronic journals and other databases and are adjacent to, but separated from, “wet” laboratories. The building includes an 80-seater seminar room. Among the extensive range of facilities available are three X-ray single crystal diffractometers, an X-ray powder diffractometer, 250MHz, 300MHz, 400 MHz and 500 MHz NMR spectrometers, two ESI-TOF mass spectrometers, one linked to a glove box, chemoinformatics support, computational modelling facilities, and GC and LC facilities. Within the Faculty of Science is located a science workshop for the manufacture of purpose-designed equipment. Within the University there is a Microscopy and Analysis Suite with TEM, SEM and scanning probe (including STM and AFM) microscopes. The Library and Learning Centre (LLC) is open 24 hours a day. The LLC has approximately 450 networked PCs and a large array of software for general use. There is a single entry point to the degree concurrent with the start of the undergraduate year. This enables the student to participate both in the taught Units and in the initial induction programme with all other postgraduates in the department. The programme introduces students to the research activity in the department and its support infrastructure, including facilities, courses, technical support and equipment. There is a detailed programme handbook including outlines for each unit which is available to the students as a hard copy and on the VLE. The student is assigned a Personal Tutor, who meets regularly with the student to review progress during the programme. The programme has a Director of Studies, who oversees it. The Department of Chemistry also has a Director of Postgraduate Studies who ensures the proper functioning of the training programme. The monitoring of student progress is dealt with by the Faculty of Science Graduate School, and the students will have access to the new Graduate Centre. 6 The Personal Tutor and Director of Studies are able to respond to many of the questions and concerns raised by their students. However, there is also a range of specialist student support services that offer both information and advice to support these staff working with their students, as well as take referrals to work more directly with the students. Students can also self-refer to these services. These services can provide information, advice and support in relation to accommodation, emotional difficulties, assessment of needs and provision of support relating to disability, student funding, general welfare, academic problems, student discipline and complaints, careers, international students, spiritual matters, part time work, security and personal safety. The Students’ Union can also provide advocacy for students. More information about these services can be accessed via: Student Support and Resources web pages1. There are also Medical and Dental Centres, and a Chaplaincy on campus that are very experienced in meeting the needs of a student population, as well as a University nursery and vacation play scheme to provide childcare for older children during the school holidays. A potential support issue with MSc programmes relates to accommodation at the end of the summer project period. The Department aims to complete project assessment before midSeptember, when university accommodation needs to be vacated. Induction events for the MSc students involve departmental and faculty events. The Director of Studies provides programme information and timetables, and discuss options with the students, whereas issues such as safety will be dealt with at the departmental level. Admissions criteria (including arrangements for APL/APEL) Admissions processes conform to institutional guidance on the Recruitment, Selection and Admission of Students. Selection is based on a formal application that includes a Statement of Purpose, documentary evidence of degree certificates, transcripts, English language qualifications and references. Students should normally have a 2.1 or higher first degree or equivalent in Chemistry, or a chemistry-related subject. Prior study of the drug discovery process or specialisation in medicinal chemistry is not required. Students may also enter the Programme of Study with a taught Masters degree in an appropriate subject. Consideration is given to those who have not acquired the requisite standard but who have substantial relevant professional experience using the University’s APL/APEL recommendations as a guide. For those with English as a second language, a minimum overall IELTS score of 6.5 (or equivalent), with nothing less than 6.0 on all elements, is normally required. Pre-sessional English language training may be offered to help some applicants to obtain this level of attainment. Summary of assessment and progression regulations The programmes are fully compliant with the PGT NFAAR (New Framework for Assessment: Assessment Regulations). http://www.bath.ac.uk/registry/nfa/nfaar-pgt.pdf Progression regulations implements the NFAAR for PGT students. The pass mark for all units is 40%. The mix of assessment methods used for a unit varies in line with its specific aims and objectives and is described in the unit catalogue. To obtain the Diploma, students must pass units worth 60 credits. To obtain the MSc, students must pass units worth 90 1 http://www.bath.ac.uk/students/support/ 7 credits. Failure of units worth up to 12 credits in the range 35-39% may be awarded by compensation. Students who fail units worth up to 24 credits may, subject to satisfactory completion of any supplementary assessment, obtain the MSc. Such assessment is either given a pass at 40% or is failed. All examination scripts and written reports are made available to the External Examiner along with the assessments. Students are normally be eligible for the award of a Postgraduate Diploma with Distinction if they achieve an average mark across the taught units of at least 70%. Students are normally be eligible for the award of a Postgraduate Diploma with Merit if they achieve an average mark across the taught units of at least 60%. Students are normally eligible for the award of a Masters degree with Distinction if they achieve a project average of at least 70% and an average mark across the taught units of at least 70%. Students are normally eligible for the award of a Masters degree with Merit if they achieve a project average of at least 60% and an average mark across the taught units of at least 60%. Indicators of quality and standards (e.g. professional accreditation) To assure continuing excellence in its quality and standards, the University of Bath has a quality management framework including: 1. A Quality Assurance Code of Practice and associated regulations and policies 2. A learning, teaching and quality committee structure which monitors quality and standards and instigates action for enhancement. For further information: Governance Review and Monitoring 3. Staff development arrangements that assist staff in enhancing their own performance as educators, as researchers or as professional support services staff. Students are involved in many of these processes. The emphasis here is upon the informed student voice - engaging with students as academic citizens to ensure they have opportunities to take an active part in shaping their own learning. A more detailed overview of the University’s Quality Management Framework is set out in a summary document. The University’s management of its academic standards and quality is subject to external institutional review by the Quality Assurance Agency on a six year cycle. In its 2013 Institutional Review, the QAA confirmed that the University met its expectations for the management of standards, the quality of learning opportunities, and the enhancement of learning opportunities. The University was commended on its provision of information. Professional bodies (such as the Royal Society of Chemistry) require particular standards and content in our programmes so that students exit able to claim professional registration or recognition, enabling them to progress successfully in their subsequent careers. Current professional accreditations are reviewed periodically by the bodies concerned. They are shown against each relevant programme in the prospectus. The full list can be seen here: QA8 Register of Accreditations. 8 In the 2008 Research Assessment Exercise, 60% of the research within the Department of Chemistry was judged as either internationally excellent or world leading, whereas 100% of the research was recognised internationally for its originality, significance and rigour. The Department of Chemistry currently has an EPSRC grant income in excess of £13M. Sources of other information Departmental website (www.bath.ac.uk/chemistry). 9 Programme Code: TSCH-AFM04 Programme Title: MSc Chemistry for Drug Discovery Award Type: Master of Science Award Title: MASTER OF RESEARCH Mode of Attendance: Full-time State if coexistent M-level programme: State any designated alternative programme(s): Postgraduate Diploma in Chemistry for Drug Discovery Approving body and date of approval: S1 Compulsory 6 CH50102 Advanced group work in practical chemistry Compulsory 6 CH50198 Chemistry of the cell Compulsory 6 Optional: Select a minimum of 6 and a maximum of 9 credits. 3 CH20160 Major therapeutic areas Compulsory 6 CH40210 Future of drug discovery Compulsory 3 CH50199 The chemistry of physiology and drug properties Compulsory 6 CH50200 Preparation for research project Compulsory 12 Unit Title CH40098 Techniques in drug discovery CH40206 Topics in organic chemistry II CH40209 Blockbuster drugs S2 CH40068 Physical organic chemistry 3 CH40211 Chemistry beyond the molecule Organic and inorganic aspects of homogeneous CH40219 catalysis Dissert. 3 3 Optional: Select a minimum of 6 and a maximum of 9 credits. 3 3 3 CH40230 DNA in the modern world 3 PA40155 Research topics in natural products 6 CH50201 Masters research project Compulsory Notes 3 CH40037 Synthesis of medicinal compounds CH40086 Inorganic chemistry in biological systems Placement or Study Abroad Status CH50100 Postgraduate training module Period of Unit Code Study DEU Status Unit Status Credits Stage Part Year 1 30 10
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