Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |1 Compare and contrast Mitosis and Meiosis. Interphase is the phase of the cell cycle in which a typical cell spends most of its life. The cell is actively living, and preparing for later cell division by duplicating its DNA. In interphase, the cell gets itself ready for mitosis or meiosis. Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |2 A chromatid is one copy of a newly replicated chromosome, which typically is joined to the other copy by a single centromere. The replicated DNA is made during Interphase. Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Stages of Mitosis Chromatin is a complex of DNA and proteins that forms chromosomes within the nucleus of eukaryotic cells. Weeks-01-03-Mitosis-Meiosis-Intro-01A Page |3 Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |4 Prophase is a stage of mitosis in which the chromatin condenses into double rod-shaped structures called chromosomes in which the chromatin becomes visible. Since the genetic material has been replicated in the prior interphase of the cell cycle, there are two identical copies of each chromosome in the cell. Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |5 During metaphase — the second stage of mitosis the chromosomes, pulled by the spindle fibers, line up along the middle of the cell, halfway between the centrosomes in the middle of the dividing cell. The chromosomes are now maximally condensed Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |6 During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes. The chromosomes are separated by a structure called the mitotic spindle. The mitotic spindle is made of many long proteins called microtubules, which are attached to a chromosome at one end and to the pole of a cell at the other end. The sister chromatids are separated simultaneously at their centromeres. The separated chromosomes are then pulled by the spindle to opposite poles of the cell. Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |7 During telophase the chromosomes have reached the poles and they begin to uncoil and become less condensed (reversing the process that occurred during prophase). Two new nuclear envelopes begin to form around each of the two separated sets of unreplicated chromosomes. As decondensation of the chromosomes proceeds, the nucleoli (which disappeared during prophase) form once again. Weeks-01-03-Mitosis-Meiosis-Intro-01A Year 10 Science -Term-4-Weeks 1 - 3 - Mitosis-Meiosis - Introduction Page |8 The Cell Cycle and Cancer https://www.youtube.com/watch?v=lpAa4TWjHQ4 (7 min) Mitosis: The Amazing Cell Process that Uses Division to Multiply! https://www.youtube.com/watch?v=gwcwSZIfKlM (7 min) Meiosis: The Great Divide https://www.youtube.com/watch?v=toWK0fIyFlY (7 min) Chromosome Numbers During Division: Demystified! https://www.youtube.com/watch?v=gcz1FOWw0Cg (6 min) Online Mitosis Quiz http://www.biologycorner.com/quiz/qz_mitosis.html http://www.softschools.com/quizzes/biology/mitosis/quiz2428.html http://www.syvum.com/cgi/online/mult.cgi/squizzes/biology/mitosis.tdf?0 http://school.discoveryeducation.com/quizzes6/muskopf/mitosis1.html Online Meiosis Quiz http://www.biologycorner.com/quiz/qz_meiosis.html http://www.softschools.com/quizzes/biology/meiosis/quiz2437.html http://biology.about.com/library/weekly/blmeios1q.htm Weeks-01-03-Mitosis-Meiosis-Intro-01A
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