ThangiahGeethaetal.,SupplementalTable2.Uniquepeptidesdetectedwithaminimumof95%confidenceinatleast1outof10samples
GeneName
Smtn
Pik3cb
PrpteinName
Smoothelin
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
ProteinIPIaccessionnumbers
IPI00361871,IPI00561311
Protein
Number Number Number Percentage
molecularweight ofunique ofunique oftotal sequence
(Da)
peptides spectra spectra coverage
Peptidesequence
99862
10
10
13
13.70%
AADGSAVSTVTK
Previous Next
amino
amino
acid
acid
R
T
Mascot
Mascot Identity
Ionscore score
94.1
28.1
Numberof
enzymatic Variablemodifications
termini
identifiedbyspectrum
2
Observed Actualpeptide
m/z
mass(AMU)
553.7888 1,105.56
Calculated+1H
Actualminus
Peptide
PeptideMass Spectrum calculatedpeptide start
(AMU)
charge
mass(PPM)
index
1,106.57
2
0.36
659
Peptide
stop
index
670
Exclusive
TRUE
IPI00208989
122595
K
88.1
2
717.8447
1,433.67
1,434.68
2
0.48
515
529
TRUE
548.7739
1,033.01
898.4304
982.978
864.9576
590.3178
982.4927
482.2854
757.4937
795.3967
545.8007
1,095.53
2,064.01
1,794.85
1,963.94
1,727.90
1,178.62
2,944.45
962.5552
756.4859
1,588.78
1,089.59
1,096.54
2,065.01
1,795.85
1,964.94
1,728.90
1,179.63
2,945.45
963.5628
757.4937
1,589.78
1,090.59
2
2
2
2
2
2
3
2
1
2
2
1.48
2.03
1.52
4.87
3.06
1.27
5.69
0.23
0.03
0.71
0.48
551
784
69
649
1251
557
208
83
723
63
162
560
802
85
667
1267
567
235
91
729
77
171
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
526.7432
443.724
445.2358
812.4351
829.9633
902.9786
888.9769
454.7134
619.3074
1,051.47
885.4324
888.4559
2,434.28
1,657.91
1,803.94
1,775.94
907.4111
1,236.60
1,052.48
886.4383
889.4632
2,435.28
1,658.91
1,804.94
1,776.94
908.4188
1,237.60
2
2
2
3
2
2
2
2
2
2.82
2.18
0.52
2.97
4.29
2.66
4.14
0.04
2.40
746
34
2204
93
28
33
82
581
566
755
43
2212
115
42
50
97
587
576
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2,234.01
950.4581
1,073.54
2,213.02
1,318.65
2,165.10
2,293.19
1,291.64
2,138.09
2,266.19
2,111.05
2,239.14
1,241.70
1,115.64
2,235.01
951.4649
1,074.54
2,214.02
1,319.65
2,166.10
2,294.20
1,292.64
2,139.09
2,267.18
2,112.04
2,240.14
1,242.71
1,116.64
2
2
2
3
2
2
3
2
2
3
2
2
2
2
0.26
1.00
1.06
1.40
1.88
1.20
1.99
1.45
1.56
3.84
5.05
4.32
0.52
1.56
12
169
1911
1539
202
202
202
240
240
240
266
266
96
875
30
177
1920
1558
212
219
220
250
257
258
283
284
107
884
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,157.46
1,158.47
2
2.56
1548
1557
TRUE
1,671.70
1,664.84
1,046.53
1,122.56
1,211.55
1,243.58
1,560.72
1,907.89
1,802.81
2,219.06
2,219.06
2,219.07
2,219.06
2,139.09
1,672.70
1,665.84
1,047.53
1,123.56
1,212.55
1,244.59
1,561.72
1,908.88
1,803.81
2,220.07
2,220.07
2,220.07
2,220.07
2,140.10
2
2
2
2
2
2
2
2
3
3
3
3
3
3
3.31
3.83
0.97
0.47
0.33
0.56
1.82
5.20
0.43
0.15
0.51
2.82
0.51
1.52
1548
441
437
348
328
1079
927
180
340
285
285
285
285
285
1562
455
445
357
337
1090
940
196
355
304
304
304
304
304
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2,177.99
946.5419
1,367.80
1,117.56
1,388.69
987.4996
871.5126
1,559.78
1,783.92
1,740.86
2,179.00
947.5413
1,368.81
1,118.57
1,389.70
988.5064
872.5207
1,560.79
1,784.93
1,741.87
3
2
2
2
2
2
2
2
2
2
0.82
8.80
0.24
0.25
0.55
1.03
0.31
1.51
1.80
2.08
320
8
8
285
285
183
485
356
146
620
338
16
20
294
296
191
492
369
162
635
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,251.65
1,263.69
2,723.44
1,962.00
1,677.82
2,345.02
1,318.69
2,367.01
1,252.66
1,264.69
2,724.44
1,963.01
1,678.82
2,346.01
1,319.70
2,368.02
2
2
3
2
2
3
2
3
2.95
1.19
5.53
1.08
3.37
4.13
1.23
0.38
794
72
267
994
195
403
534
1010
805
82
297
1010
208
422
546
1030
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
5
5
7
6.36%
AAEIASGDSANVSSR
G
29.1
Kif5b
Copb2
Clip2
Lmo7
Rrbp1
Specc1l
Dpysl3
Hadhb
Myo1d
Tubb6
Jup
Kinesin1heavychain
Coatomersubunitbeta'
111kDaprotein
LMO7b
similartoRibosomebindingprotein1
CytospinA
Isoform2ofDihydropyrimidinaserelatedprotein3
Trifunctionalenzymesubunitbeta,mitochondrial
MyosinId
Tubulin,beta6
Junctionplakoglobin
IPI00364904
IPI00231953
IPI00476704
IPI00421345
IPI00188079
IPI00372846
IPI00203250
IPI00198467
IPI00207989
IPI00195673
IPI00421429
109514
102535
111364
156634
143655
124324
73882
51398
116081
50041
81784
13
4
28
44
12
11
5
3
42
5
10
13
4
31
53
12
11
5
3
50
5
10
13
4
43
78
15
19
6
3
166
12
27
17.30%
5.97%
34.30%
37.80%
10.90%
12.50%
12.60%
6.11%
46.10%
30.20%
16.60%
AAEMMASLLK
AAESLADPTEYENLFPGLK
AAEVGDDFLGDFVVGER
AAGMKPDSSHFILGSSSEK
AAGPLESSGIEEVTQLK
AALAATLEEYK
AALAGGTTMIIDHVVPEPESSLTEAYEK
AALSGLLYR
AALTIIR
AALVDLEPGTMDSVR
AAMIVNQLSK
R
K
K
R
R
K
K
R
K
R
K
D
E
V
E
E
A
W
T
Y
S
K
29.6
71.6
89.5
77
70.6
95.2
33.8
54.4
31.4
74.8
58.3
28.4
29.7
30.3
30
28.2
28
29.4
23.2
24.8
29.6
27.6
2
2
2
2
2
2
2
2
2
2
2
Rai14
Irs1
Mprip
Pkm2
Kpnb1
Eno1
Anxa1
Myh9
Myh9
Isoform2ofAnkycorbin
Insulinreceptorsubstrate1
258kDaprotein
IsoformM2ofPyruvatekinaseisozymesM1/M2
Importinsubunitbeta1
Alphaenolase
AnnexinA1
Myosin9
Myosin9
IPI00372146
IPI00199662
IPI00392930
IPI00339197,IPI00764193
IPI00204261
IPI00464815,IPI00767147
IPI00231615,IPI00777179
IPI00209113
IPI00209113
105981
131160
257845
57922
97167
47111
38813
226326
226326
43
38
37
4
8
3
7
122
132
50
51
49
4
8
3
8
194
196
62
99
105
7
9
4
14
2067
883
48.90%
40.60%
19.50%
11.30%
13.20%
10.40%
31.50%
51.90%
55.20%
AAMSDAMVPK
AASEAGGPAR
AATEALGEK
AATESFASDPILYRPVAVALDTK
AAVENLPTFLVELSR
AAVPSGASTGIYEALELR
AAYLQETGKPLDETLK
ADEWLMK
ADFCIIHYAGK
K
R
K
R
R
R
K
K
K
A
L
S
G
V
D
K
N
V
35.2
51.2
33.3
42.2
75.2
127
52.8
42.4
41.2
27.1
25.7
26.9
26.4
25.5
28.5
27.4
26.8
28.4
2
2
2
2
2
2
2
2
2
Myo1d
Hsp90ab1
Myh3
Myh3
Krt17
Krt17
Krt17
Krt14
Krt14
Krt14
Krt10
Krt10
Hsp90ab1
Flii
MyosinId
HeatshockproteinHSP90beta
Myosin3
Myosin3
Keratin,typeIcytoskeletal17
Keratin,typeIcytoskeletal17
Keratin,typeIcytoskeletal17
Keratin,typeIcytoskeletal14
Keratin,typeIcytoskeletal14
Keratin,typeIcytoskeletal14
Keratin,typeIcytoskeletal10
Keratin,typeIcytoskeletal10
HeatshockproteinHSP90beta
FlightlessIhomolog
IPI00207989
IPI00471584
IPI00201578
IPI00201578
IPI00370073
IPI00370073
IPI00370073
IPI00421855
IPI00421855
IPI00421855
IPI00421806,IPI00551673
IPI00421806,IPI00551673
IPI00471584
IPI00211698
116081
83266
223846
223846
48106
48106
48106
52667
52667
52667
56489
56489
83266
144843
42
13
69
86
22
15
22
8
7
8
10
13
9
8
50
13
76
104
33
20
33
12
11
12
13
22
9
8
166
16
172
217
468
292
468
90
150
90
131
244
25
12
46.10%
21.70%
42.20%
50.30%
41.10%
33.50%
41.10%
26.80%
24.70%
26.80%
18.10%
21.50%
13.50%
7.80%
ADFVLMDTVSMPEFMANLR
ADHGEPIGR
ADIAESQVNK
ADIQMALEEAEAALEHEEAK
ADLEMQIENLK
ADLEMQIENLKEELAYLK
ADLEMQIENLKEELAYLKK
ADLEMQIESLK
ADLEMQIESLKEELAYLK
ADLEMQIESLKEELAYLKK
ADLEMQIESLTEELAYLK
ADLEMQIESLTEELAYLKK
ADLINNLGTIAK
ADLTALFLPR
K
R
R
K
R
R
R
R
R
R
K
K
K
K
L
G
L
I
E
K
N
E
K
N
K
N
S
Q
89.2
32.5
63.4
59.3
31
50
41.1
48.9
61.5
41.6
95.1
99.2
72.3
76.5
30.6
27.3
29.1
30.7
28.4
29.1
27.6
28.3
29.1
27
29.8
28.7
26.5
25.8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Myh10
234kDaprotein
IPI00391300
233603
70
82
145
45.50%
ADMEDLMSSK
R
D
50.3
25.9
2
Myh10
Hadha
Sept9
Krt76
Kb15
Lmo7
Myh3
Anxa2
Tmpo
Mprip
Mprip
Mprip
Mprip
Mprip
234kDaprotein
Trifunctionalenzymesubunitalpha,mitochondrial
septin9isoform1
TypeIIkeratinKb9
TypeIIkeratinKb15
LMO7b
Myosin3
IsoformShortofAnnexinA2
75kDaprotein
258kDaprotein
258kDaprotein
258kDaprotein
258kDaprotein
258kDaprotein
IPI00391300
IPI00212622
IPI00215235,IPI00782707
IPI00421812
IPI00207038
IPI00421345
IPI00201578
IPI00325146
IPI00569391
IPI00392930
IPI00392930
IPI00392930
IPI00392930
IPI00392930
233603
82649
64850
61742
58080
156634
223846
38662
74885
257845
257845
257845
257845
257845
70
9
3
2
3
38
77
8
6
37
32
33
32
37
82
9
3
2
6
47
85
11
6
49
43
42
43
49
145
9
3
6
107
123
149
13
6
105
100
71
100
105
45.50%
16.40%
6.42%
8.43%
16.90%
31.90%
47.90%
30.10%
12.70%
19.50%
18.20%
17.40%
18.20%
19.50%
ADMEDLMSSKDDVGK
ADMVIEAVFEDLAVK
ADTLTLEER
AEAEALYQTK
AEAESWYQTK
AEAQAQAEAEAR
AEDEEEINAELTAK
AEDGSVIDYELIDQDAR
AEEPHVSDQSVFSSER
AEEQLPPLLSPPSPSTPHSR
AEEQLPPLLSPPSPSTPHSR
AEEQLPPLLSPPSPSTPHSR
AEEQLPPLLSPPSPSTPHSR
AEEQLPPLLSPPSPSTPHSR
R
K
K
K
R
R
R
R
R
R
R
R
R
R
N
H
V
L
Y
K
K
E
E
R
R
R
R
R
32.8
98.5
50
60.5
73.9
83.9
89.1
71.4
39
50.3
58.7
46.6
58.7
37
29
29.4
28.3
28.1
28
28.4
29.9
29.9
30
30
30
30.1
30
28.3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Mprip
Nexn
Nexn
Rai14
Rai14
Tpm1
Smtn
Lrrfip2
Nexn
Specc1l
257845
78377
78377
105981
105981
32831
99862
49756
78377
124324
32
19
17
29
34
35
10
6
20
21
43
22
21
33
39
57
10
6
26
23
100
61
50
50
69
309
13
12
63
36
18.20%
25.80%
24.10%
36.00%
39.20%
70.80%
14.40%
16.20%
26.80%
25.00%
AEHMETNMLILTTPSSDTR
AEILLSSSK
AEILLSSSKPVPK
AEISSIQENK
AEISSIQENKDR
AELSEGQVR
AELTLGLR
AEQDIATLEQSISR
AEQEGDDSLLITVVPAK
AETLASSLQEDLAHTR
K
K
K
K
K
R
R
K
R
K
Q
P
S
D
L
Q
A
L
S
N
57.8
28.7
50.8
60.1
54.7
33
64
88.9
75.7
77.8
30.3
25.4
21.2
28.1
28.3
26.9
25.8
29.6
28.3
29.5
2
2
2
2
2
2
2
2
2
2
Pik3cb
Hnrpm
Arbp
Cltc
Casq2
Tuba1b
Gsn
Lmo7
258kDaprotein
IPI00392930
Isoform1ofNexilin
IPI00209938
Isoform1ofNexilin
IPI00209938
Isoform2ofAnkycorbin
IPI00372146
Isoform2ofAnkycorbin
IPI00372146
tropomyosin1,alphaisoformc
IPI00210945
smoothelin
IPI00361871,IPI00561311
Leucinerichrepeatflightlessinteractingprotein2
IPI00373564,IPI00780550
Isoform1ofNexilin
IPI00209938
CytospinA
IPI00372846
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
IPI00208989
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
60SacidicribosomalproteinP0
IPI00200147
Clathrinheavychain1
IPI00193983
Calsequestrin2
IPI00231901
Tubulinalpha1Bchain
IPI00339167
Isoform2ofGelsolin
IPI00923716
LMO7b
IPI00421345
122595
77613
34198
191585
49386
50134
80911
156634
5
9
4
10
4
11
14
39
5
9
4
10
5
17
18
49
7
11
10
11
8
69
34
116
6.36%
16.70%
20.80%
8.42%
12.60%
37.50%
30.10%
32.70%
AFGEDAVGVIFK
AFITNIPFDVK
AFLADPSAFAAAAPVAAATTAAPAAAAAPAK
AFMTADLPNELIELLEK
AFQEAAEHFQPYIK
AFVHWYVGEGMEEGEFSEAR
AGALNSNDAFVLK
AGDEDRGQLEDDAVYEDQSQK
R
R
K
K
K
R
K
R
N
W
V
I
F
E
T
L
82.7
56.5
75.1
54.4
34
40.1
84.3
64.3
28.4
26.5
25.3
28.5
29.4
30.4
27.9
31
2
2
2
2
2
2
2
2
Vcl
Acta1
Scin
Gsn
Myh3
Myh3
LOC682649
Emilin1
Thbs1
Actn4
Actn1
Actn1
Myh10
Myh10
Vinculin
Actin,alphaskeletalmuscle
Scinderin
Isoform2ofGelsolin
Myosin3
Myosin3
similartoHistoneH2Atype1
elastinmicrofibrilinterfacer1
Thrombospondin1
Alphaactinin4
Alphaactinin1
Alphaactinin1
234kDaprotein
234kDaprotein
IPI00365286
IPI00189813
IPI00365568,IPI00391226
IPI00923716
IPI00201578
IPI00201578
IPI00559107
IPI00199867
IPI00422076
IPI00213463
IPI00209082,IPI00454431
IPI00209082,IPI00454431
IPI00391300
IPI00391300
116599
42034
80184
80911
223846
223846
18545
107542
129653
104900
102946
102946
233603
233603
5
2
6
28
86
69
2
11
19
16
22
16
55
70
5
3
6
41
104
76
2
11
20
18
26
19
59
82
5
8
8
122
217
172
5
11
38
21
34
32
166
145
5.72%
52.80%
11.30%
49.80%
50.30%
42.20%
8.93%
15.40%
17.70%
24.30%
41.70%
35.10%
38.10%
45.50%
AGEVINQPMMMAAR
AGFAGDDAPR
AGGVASGLNHVLTNDLTAK
AGKEPGLQIWR
AGLLGTLEEMR
AGLLGTLEEMRDER
AGLQFPVGR
AGPPGPPGLQGPPGPAGPPGPPGK
AGTLDLSLSLPGK
AGTQIENIDEDFRDGLK
AGTQIENIEEDFR
AGTQIENIEEDFRDGLK
AGVLAHLEEER
AGVLAHLEEERDLK
K
K
K
K
K
K
R
K
K
K
K
K
R
R
Q
A
R
V
D
L
V
D
Q
L
D
L
D
I
37.7
81.3
35.3
33.3
54.1
38.3
57
38.5
81.2
35.8
50.2
42.2
76.4
52.7
29.5
26.3
26.8
24.5
28.7
29.8
28
26.4
25.9
30
28.9
29.8
28
27.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Cltc
Ktn1
Clathrinheavychain1
similartokinectin1
Serine/threonineproteinphosphatasePP1betacatalytic
subunit
Isoform2ofAnkycorbin
ATPsynthasesubunitbeta,mitochondrial
Isoform1ofNexilin
phosphoenolpyruvatecarboxykinase2
similartoSignalrecognitionparticle72kDaprotein
MyosinId
Isoform1ofTubulinbeta5chain
Alphaactinin1
Isoform1ofTropomyosinalpha1chain
IPI00193983
IPI00563574
191585
151567
27
3
29
3
29
3
21.50%
3.17%
AHMGMFTELAILYSK
AHQLSVTSQVQELQNLLR
R
K
F
G
36.6
37.4
29.6
25.2
Ppp1cb
Rai14
Atp5b
Nexn
Pck2
Srp72
Myo1d
Tubb5
Actn1
Tpm1
IPI00203390
IPI00372146
IPI00551812
IPI00209938
IPI00869844
IPI00763992,IPI00766213,IPI00766719
IPI00207989
IPI00197579
IPI00209082,IPI00454431
IPI00197888
37170
105981
56336
78377
70725
73844
116081
49653
102946
32664
4
31
3
17
3
3
43
13
22
3
5
39
4
23
3
3
55
14
26
5
5
61
5
47
3
3
272
66
34
27
16.20%
36.40%
9.83%
26.70%
6.56%
7.39%
47.00%
36.50%
41.70%
60.90%
AHQVVEDGYEFFAK
AHSEVAQVR
AIAELGIYPAVDPLDSTSR
AIDLEIK
AIDTSQLFSIPK
AIELLQEFSDQHPENAAEIK
AIFVTDR
AILVDLEPGTMDSVR
AIMTYVSSFYHAFSGAQK
AISEELDHALNDMTSI
R
K
R
R
R
K
R
R
K
K
R
S
I
E
D
L
H
S
A
47.5
36.2
75.3
41.4
49.1
34.7
49
76.9
33.7
67.8
29.1
26.7
28
25.8
26.9
30
26.6
29.5
30.1
30.1
Tpm1
Tpm2
Tpm2
Isoform1ofTropomyosinalpha1chain
Isoform1ofTropomyosinbetachain
Isoform1ofTropomyosinbetachain
IPI00197888
IPI00230775
IPI00230775
32664
32820
32820
3
17
17
6
26
28
30
93
167
68.30%
67.60%
65.80%
AISEELDHALNDMTSI
AISEELDNALNDITSL
AISEELDNALNDITSL
K
K
K
46.9
48.1
108
29.5
30
29.3
2
2
2
Myh3
Myosin3
68
78
99
43.10%
AITDAAMMAEELKK
K
E
49.8
29.5
2
Tnnt2
Hspa5
Myh9
Myh9
Myh9
Gsn
Lamp1
Vcl
RGD1563532
Dbn1
Actn1
Anxa1
Pabpc1
Myh10
Myh10
Myh9
Myh9
Myh9
Krt17
Cltc
Myh10
Myh9
Myh9
Myh9
Myh10
Nes
Isoform2ofTroponinT,cardiacmuscle
78kDaglucoseregulatedprotein
Myosin9
Myosin9
Myosin9
Isoform2ofGelsolin
Lysosomeassociatedmembraneglycoprotein1
Vinculin
86kDaprotein
IsoformAofDrebrin
Alphaactinin1
AnnexinA1
Polyadenylatebindingprotein1
234kDaprotein
234kDaprotein
Myosin9
Myosin9
Myosin9
Keratin,typeIcytoskeletal17
Clathrinheavychain1
234kDaprotein
Myosin9
Myosin9
Myosin9
234kDaprotein
Isoform1ofNestin
17
15
122
132
138
14
2
17
5
7
13
3
6
58
46
123
132
138
13
27
58
119
132
107
49
16
26
19
194
196
222
17
2
18
5
8
17
3
6
67
52
194
196
222
17
29
67
194
196
169
53
17
111
32
2067
883
3511
72
4
25
5
10
28
3
9
363
210
2027
883
3511
339
29
363
3095
883
1242
157
27
43.90%
28.70%
51.90%
55.20%
55.70%
31.50%
6.63%
20.40%
7.64%
17.40%
30.80%
14.50%
13.20%
40.00%
33.80%
52.30%
55.20%
55.70%
26.30%
21.50%
40.00%
51.60%
55.20%
49.10%
33.40%
10.50%
AKELWQSIHNLEAEK
AKFEELNMDLFR
AKLQEMESAVK
AKQTLENER
AKQTLENERGELANEVK
ALAELAA
ALALNVFSVQVQAFR
ALASQLQDSLK
ALATSAENTLVFR
ALDEVTSSQPPPPPPPPPPAQEAQESAPR
ALDFIASK
ALDLELK
ALDTMNFDVIK
ALEEALEAK
ALEEALEAKEEFER
ALEEAMEQK
ALEEAMEQK
ALEEAMEQKAELER
ALEEANTELEVK
ALEHFTDLYDIK
ALELDPNLYR
ALELDSNLYR
ALEQQVEEMK
ALEQQVEEMKTQLEELEDELQATEDAK
ALEQQVEEMR
ALGEEPLMSLK
K
R
K
K
K
R
K
R
K
R
K
K
R
R
R
R
R
R
R
R
R
K
R
R
R
K
F
S
S
G
A
V
D
S
L
G
G
G
E
Q
A
A
L
I
R
I
I
T
L
T
I
30.7
59.2
49.5
44
29
32.6
69.3
54.1
56.6
85.3
51.6
41.4
79.7
46
72.7
58.9
48.5
50.7
67.9
47.1
59.1
74
74.2
84.3
51.4
30.4
27.9
29.6
28.3
27.5
28
22.9
22.3
27.6
27.5
29.6
24.4
25.8
28.5
28
30.3
26.8
27.8
29.6
28.7
28.5
28.6
28.1
28
31.4
28.1
29
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Myl6l
Anxa6
Eef2
Hsp90ab1
Hsp90aa1
Dsp
Myh9
Jup
Myosinlightpolypeptide6
AnnexinA6
Elongationfactor2
HeatshockproteinHSP90beta
HeatshockproteinHSP90alpha
similartodesmoplakinisoformIisoform2
Myosin9
Junctionplakoglobin
IPI00201578
223846
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00206624
72331
IPI00209113
226326
IPI00209113
226326
IPI00209113
226326
IPI00923716
80911
IPI00206336
43952
IPI00365286
116599
IPI00568788,IPI00768137
85638
IPI00231407,IPI00231784
77453
IPI00209082,IPI00454431
102946
IPI00231615,IPI00777179
38813
IPI00189074
70683
IPI00391300
233603
IPI00391300
233603
IPI00209113
226326
IPI00209113
226326
IPI00209113
226326
IPI00370073
48106
IPI00193983
191585
IPI00391300
233603
IPI00209113
226326
IPI00209113
226326
IPI00209113
226326
IPI00391300
233603
IPI00194103
208776
IPI00365944,IPI00392935,IPI00817070,I
PI00896236
16957
IPI00421888,IPI00831745
75740
IPI00203214
95268
IPI00471584
83266
IPI00210566
84800
IPI00366081
332383
IPI00209113
226326
IPI00421429
81784
3
2
8
15
4
11
123
6
3
2
8
15
4
11
194
6
7
2
9
32
4
39
2027
17
24.50%
2.82%
12.10%
24.40%
15.60%
5.14%
52.30%
10.50%
ALGQNPTNAEVLK
ALIEILATR
ALLELQLEPEELYQTFQR
ALLFIPR
ALLFVPR
ALLQAILQTEDMLK
ALLQGK
ALMGSPQLVAAVVR
R
K
R
R
R
R
K
R
V
T
I
R
R
V
G
T
53.5
56
62.9
36.2
26.8
75.2
30.7
71.6
26.7
22.8
28.2
24.6
24.7
26.5
27.1
25.4
2
2
2
2
2
2
2
2
Hspd1
Myh3
Lmod2
Mvp
Pik3r1
60kDaheatshockprotein,mitochondrial
IPI00339148
60939
Myosin3
IPI00201578
223846
Leiomodin2
IPI00372026
61700
Majorvaultprotein
IPI00231381
96806
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
83516
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
Tnnt2
Isoform2ofTroponinT,cardiacmuscle
Tnnt3
Anxa1
Tubb6
Tubb2a
Tubb5
Isoform1ofTroponinT,fastskeletalmuscle
AnnexinA1
Tubulin,beta6
Tubulinbeta2Achain
Isoform1ofTubulinbeta5chain
LOC683313
Fdps
Keratin,typeIIcytoskeletal6A
Farnesylpyrophosphatesynthetase
LOC680312
Gnai2
Atp2a2
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00231615,IPI00777179
38813
IPI00195673
50041
IPI00475639
49889
IPI00197579
49653
IPI00393340
59233
IPI00325147
40813
IPI00190348,IPI00209163,IPI00388454,I
PI00393508,IPI00480852,IPI00551802,I
PI00556932,IPI00560461,IPI00560818,I
PI00734783,IPI00764164,IPI00766320,I
PI00768311,IPI00870721
13873
histoneH2B
GuaninenucleotidebindingproteinG(i),alpha2subunit IPI00231925
40482
IsoformSERCA2BofSarcoplasmic/endoplasmicreticulum
calciumATPase2
IPI00190020,IPI00231369
115376
Tpm2
Irs1
Isoform2ofTropomyosinbetachain
IPI00187731
Insulinreceptorsubstrate1
IPI00199662
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
Pik3ca
Myh3
Myosin3
IPI00201578
Myh9
Myosin9
IPI00209113
Myh3
Myosin3
IPI00201578
Myh3
Myosin3
IPI00201578
Myh3
Myosin3
IPI00201578
Nes
Isoform1ofNestin
IPI00194103
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
IPI00554334
Pkm2
IsoformM2ofPyruvatekinaseisozymesM1/M2
IPI00339197,IPI00764193
Ddx5
Ddx5
IPI00464718
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
IPI00554334
Smtn
smoothelin
IPI00361871,IPI00561311
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
IPI00554334
Sept9
septin9isoform1
IPI00215235,IPI00782707
Canx
Calnexin
IPI00199636
Mvp
Majorvaultprotein
IPI00231381
Sec31a
Isoform1ofProteintransportproteinSec31A
IPI00210147,IPI00515833
Rai14
Isoform2ofAnkycorbin
IPI00372146
Smtn
smoothelin
IPI00361871,IPI00561311
Hspa9
Stress70protein,mitochondrial
IPI00363265
Thbs1
Thrombospondin1
IPI00422076
Myh3
Myosin3
IPI00201578
Clip2
111kDaprotein
IPI00476704
Gsn
Isoform2ofGelsolin
IPI00923716
Tpm1
tropomyosin1,alphaisoformc
IPI00210945
Clip2
111kDaprotein
IPI00476704
Cct6a
Chaperoninsubunit6a
IPI00188111,IPI00780515
Ppp1r12a
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
Flot1
Isoform1ofFlotillin1
IPI00208784
Flot1
Isoform1ofFlotillin1
IPI00208784
Vcl
Vinculin
IPI00365286
RGD1563532 86kDaprotein
IPI00568788,IPI00768137
Gsn
Isoform2ofGelsolin
IPI00923716
Gsn
Isoform2ofGelsolin
IPI00923716
Clip2
111kDaprotein
IPI00476704
Kb23
TypeIIkeratinKb23
IPI00454476,IPI00780672
Kb15
TypeIIkeratinKb15
IPI00207038
LOC683313
Keratin,typeIIcytoskeletal6A
IPI00393340
LOC683613
similartoKeratin,typeIIcytoskeletal6G
IPI00768956
Hspa8
Heatshockcognate71kDaprotein
IPI00208205
Myo1c
MyosinIc
IPI00393867
Emilin1
elastinmicrofibrilinterfacer1
IPI00199867
Lmo7
LMO7b
IPI00421345
Actn1
Alphaactinin1
IPI00209082,IPI00454431
Cald1
Caldesmon
IPI00208118
Myh9
Myosin9
IPI00209113
Actn1
Alphaactinin1
IPI00209082,IPI00454431
Cald1
Caldesmon
IPI00208118
Krt16
TypeIkeratinKA16
IPI00421793
Copa
Copaprotein
IPI00372458
Myo1d
MyosinId
IPI00207989
Scin
Scinderin
IPI00365568,IPI00391226
Myh10
234kDaprotein
IPI00391300
Myh9
Myosin9
IPI00209113
Irs1
Insulinreceptorsubstrate1
IPI00199662
M4:Oxidation(+15.99),M5:
Oxidation(+15.99)
M4:Oxidation(+15.99)
M9:Oxidation(+15.99)
M11:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99),M11:
Oxidation(+15.99),M15:
Oxidation(+15.99)
1,118.01
476.2369
537.7761
M5:Oxidation(+15.99)
738.6808
M5:Oxidation(+15.99)
660.3311
M5:Oxidation(+15.99)
1,083.56
M5:Oxidation(+15.99)
765.4053
M5:Oxidation(+15.99)
646.8253
M5:Oxidation(+15.99)
1,070.05
M5:Oxidation(+15.99)
756.4031
M5:Oxidation(+15.99)
1,056.53
M5:Oxidation(+15.99)
1,120.58
621.8572
558.8258
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
579.7383
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
836.859
M3:Oxidation(+15.99)
833.4276
524.2706
562.286
606.781
622.7971
781.3671
954.9503
601.9437
S13:Phospho(+79.97)
740.6953
S15:Phospho(+79.97)
740.6958
S19:Phospho(+79.97)
740.6975
T16:Phospho(+79.97)
740.6958
714.0389
M4:Oxidation(+15.99),M8:
Oxidation(+15.99)
727.0051
474.2788
684.9089
559.7888
695.353
494.7576
436.7641
780.8986
892.9697
871.4382
M3:Oxidation(+15.99)
M11:Oxidation(+15.99)
626.8347
632.8518
908.8223
982.01
839.9182
782.6796
660.3527
790.0115
1,565.70
975.4421
1,836.97
1,253.69
1,204.61
1,604.78
943.5246
2,053.08
1,270.72
1,919.93
1,520.71
1,933.94
1,222.63
1,578.84
1,566.71
976.4489
1,837.98
1,254.70
1,205.62
1,605.79
944.5319
2,054.08
1,271.72
1,920.93
1,521.72
1,934.95
1,223.64
1,579.84
2
2
3
2
2
3
2
3
2
3
2
3
2
2
2.05
0.98
0.11
1.88
0.07
0.48
0.56
2.93
3.49
1.67
0.99
2.73
0.07
3.73
890
21
119
11
768
768
62
820
125
67
48
48
809
809
903
30
137
21
778
781
70
843
137
83
60
64
819
822
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
M9:Oxidation(+15.99),M10:
Oxidation(+15.99),M11:
Oxidation(+15.99)
783.8594
488.7289
613.3309
627.8532
M10:Oxidation(+15.99)
603.314
M10:Oxidation(+15.99)
535.9358
472.7701
685.3683
636.3668
640.9832
761.364
645.6557
612.3231
790.4291
M3:Oxidation(+15.99),M5:
Oxidation(+15.99)
872.429
688.7144
1,742.84
2,063.12
1,743.85
2,064.12
2
3
2.96
3.51
1312
855
1326
872
TRUE
TRUE
2
2
2
2
2
2
2
2
2
2
820.3942
498.7654
994.5244
401.2402
660.3665
761.3859
411.23
816.4196
675.3276
887.9155
1,638.77
995.5152
1,987.03
800.4648
1,318.72
2,281.13
820.4444
1,630.82
2,022.96
1,773.82
1,639.78
996.5227
1,988.03
801.4724
1,319.72
2,282.13
821.4521
1,631.83
2,023.96
1,774.82
2
2
2
2
2
3
2
2
3
2
3.15
0.41
3.40
0.35
2.90
4.99
0.19
0.05
4.18
3.46
246
786
388
456
589
349
876
63
237
269
259
794
406
462
600
368
882
77
254
284
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
1,853.78
1,796.81
1,716.85
1,854.78
1,797.82
1,717.85
2
2
2
2.59
1.45
3.36
269
269
269
284
284
284
TRUE
TRUE
TRUE
1,552.75
1,553.76
2
2.85
1759
1772
TRUE
599.3174
764.8806
417.2204
544.7904
483.0075
658.3779
831.9739
587.3281
696.8809
996.4982
432.7453
401.2402
641.8223
487.2641
832.4164
532.7506
524.7548
554.9393
673.3478
732.8751
602.324
597.3123
610.7966
1,055.17
624.7982
602.3209
1,794.93
1,527.75
1,248.64
1,087.57
1,928.00
657.3701
1,661.93
1,172.64
1,391.75
2,986.47
863.475
800.4648
1,281.63
972.5126
1,662.82
1,063.49
1,047.49
1,661.79
1,344.68
1,463.73
1,202.63
1,192.61
1,219.58
3,162.48
1,247.58
1,202.63
1,795.93
1,528.75
1,249.65
1,088.57
1,929.00
658.3776
1,662.93
1,173.65
1,392.75
2,987.48
864.4832
801.4724
1,282.64
973.5207
1,663.82
1,064.49
1,048.50
1,662.80
1,345.69
1,464.74
1,203.64
1,193.62
1,220.58
3,163.48
1,248.59
1,203.63
3
2
3
2
4
1
2
2
2
3
2
2
2
2
2
2
2
3
2
2
2
2
2
3
2
2
1.11
4.18
0.46
2.50
1.29
0.52
4.28
0.34
3.80
1.12
0.45
0.35
1.08
0.27
4.28
0.19
3.06
0.68
2.02
3.19
2.26
0.03
1.73
0.82
0.75
3.58
234
325
1793
1218
1218
725
339
571
330
401
96
251
68
1528
1528
1485
1485
1485
104
626
790
746
1530
1530
1573
537
248
336
1803
1226
1234
731
353
581
342
429
103
257
78
1536
1541
1493
1493
1498
115
637
799
755
1539
1556
1582
547
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
677.8712
500.3146
1,110.58
415.2694
408.2611
801.9445
629.3989
M3:Oxidation(+15.99)
714.4075
M3:Oxidation(+15.99),M18:
Oxidation(+15.99)
715.7175
937.4666
465.5966
729.8535
1,353.73
998.6136
2,219.15
828.5231
814.5065
1,601.87
628.3911
1,426.80
1,354.73
999.6203
2,220.16
829.5301
815.5144
1,602.88
629.3988
1,427.80
2
2
2
2
2
2
1
2
1.02
1.14
1.61
0.93
0.10
2.08
0.25
2.08
38
457
163
331
340
779
1235
178
50
465
180
337
346
792
1240
191
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2,144.13
2,809.38
1,393.77
1,457.69
2,145.13
2,810.38
1,394.78
1,458.70
3
3
3
2
3.15
1.10
1.02
1.78
38
999
297
346
58
1023
308
358
TRUE
TRUE
TRUE
TRUE
709.8945
1,417.77
1,418.78
2
1.23
263
274
TRUE
814.8829
1,627.75
1,628.76
2
0.92
179
192
TRUE
789.8779
820.4622
854.4379
862.4324
830.4544
1,577.74
1,638.91
1,706.86
1,722.85
1,658.89
1,578.75
1,639.91
1,707.86
1,723.86
1,659.90
2
2
2
2
2
0.49
4.34
3.02
0.40
3.04
147
99
283
283
283
161
113
297
297
297
TRUE
TRUE
TRUE
TRUE
TRUE
3,083.43
1,120.58
3,084.43
1,121.58
3
2
2.74
3.08
289
303
315
311
TRUE
TRUE
M11:Oxidation(+15.99)
M3:Oxidation(+15.99)
M13:Oxidation(+15.99)
M13:Oxidation(+15.99),S15:
Phospho(+79.97)
927.898
S15:Phospho(+79.97)
899.4132
859.4316
M7:Oxidation(+15.99),M8:
Oxidation(+15.99)
777.3839
M8:Oxidation(+15.99)
M6:Oxidation(+15.99)
M5:Oxidation(+15.99)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
M8:Oxidation(+15.99)
M12:Oxidation(+15.99)
2
76
6
3
3
92
7
3
3
323
9
3
6.81%
46.50%
12.80%
4.71%
ALMLQGVDLLADAVAVTMGPK
ALQEAHQQTLDDLQAEEDKVNSLSK
ALQHNTVLTELR
ALQPLEEGESEEK
R
K
R
K
G
L
F
V
83.6
72.9
28.1
32.5
27.2
30
25.4
29.5
2
2
2
2
7
8
10
9.67%
ALSEIFSHVLFR
R
F
81.3
27.4
2
14
24
111
37.00%
ALSNMMHFGGYIQK
K
A
32.7
29.2
2
8
7
6
4
15
11
8
6
4
16
38
14
14
8
69
30.50%
31.50%
30.40%
33.70%
37.60%
ALSSMGANYSSYLAK
ALTGHLEEVVLAMLK
ALTVPELTQQMFDAK
ALTVPELTQQMFDSK
ALTVPELTQQVFDAK
K
K
R
R
R
A
T
N
N
N
102
61.9
65.1
71.4
63.7
29.4
24.5
28.9
29.4
27
2
2
2
2
2
9
3
11
5
63
10
26.10%
10.20%
ALYEAELSQMQTHISDTSVVLSMDNNR
ALYEELDLR
R
K
S
S
50.1
50.2
31.3
28.4
2
2
M10:Oxidation(+15.99),M23:
Oxidation(+15.99)
1,028.82
561.2979
2
2
M2:Oxidation(+15.99),M5:
Oxidation(+15.99)
M2:Oxidation(+15.99)
888.4105
796.384
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M8:
Oxidation(+15.99),M13:
Oxidation(+15.99)
M2:Oxidation(+15.99)
781.4204
1,560.83
1,561.83
2
4.40
221
236
TRUE
1,014.97
562.7639
2,027.92
1,123.51
2,028.93
1,124.52
2
2
1.06
3.51
134
254
149
262
FALSE
TRUE
968.9755
692.8759
935.4877
530.7633
487.2699
551.3187
500.2605
1,935.94
1,383.74
1,868.96
1,059.51
972.5242
1,100.62
998.5054
1,936.94
1,384.74
1,869.97
1,060.52
973.5319
1,101.63
999.5112
2
2
2
2
2
2
2
3.30
0.29
0.28
1.19
0.10
2.36
2.05
163
1679
1756
1365
1436
1436
173
179
1690
1771
1373
1445
1446
181
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
4
2
4
4
4
19.00%
16.10%
AMGIMNSFVNDIFER
AMGNLQIDFADPQR
K
K
I
A
99.7
56.5
30.4
29.6
M5:Oxidation(+15.99),M6:
Oxidation(+15.99)
M5:Oxidation(+15.99)
M13:Oxidation(+15.99)
M11:Oxidation(+15.99)
M11:Oxidation(+15.99)
59
87
73
100
AMGVVVATGVNTEIGK
K
I
59.8
27.7
2
74.30%
40.60%
AMKDEEKMELQEMQLK
AMSDEFRPR
R
R
E
T
61.7
45.4
31
27.8
2
2
124233
223846
226326
223846
223846
223846
208776
15
60
119
76
76
76
16
17
66
194
92
92
92
17
28
306
3095
323
323
323
27
18.40%
39.10%
51.60%
46.50%
46.50%
46.50%
10.50%
AMYVYPPNVESSPELPK
ANLLQAEVEELR
ANLQIDQINTDLNLER
ANSEVAQWR
ANSLAAALDK
ANSLAAALDKK
APEVEDLAR
R
R
K
K
R
R
R
H
A
S
T
K
Q
R
59.7
71.5
133
45.1
52.1
54.5
50
29.9
27.1
28.6
27.8
26.6
26.7
26.3
2
2
2
2
2
2
2
81251
57922
69223
27
3
2
33
3
2
100
3
3
50.10%
7.88%
5.04%
APGPGPPPAAR
APIIAVTR
APILIATDVASR
R
R
K
N
G
58
45.4
71.7
28.6
18
24.7
2
2
2
494.2728
420.7694
613.8591
986.53
839.5232
1,225.70
987.5378
840.5308
1,226.71
2
2
2
0.04
0.26
0.47
712
450
392
722
457
403
81251
99862
27
12
33
13
100
13
50.10%
17.80%
APPPGGEGDGSEPAPDFPVLLLER
APPTLLSTSSGGK
R
R
L
N
67.1
66.1
29.9
27.6
2
2
1,209.10
608.335
2,416.19
1,214.65
2,417.20
1,215.66
2
2
0.87
3.04
257
493
280
505
TRUE
TRUE
81251
64850
67239
96806
135256
105981
99862
73840
129653
223846
111364
80911
32831
111364
58000
115268
47481
47481
116599
85638
80911
80911
111364
62207
58080
59233
57419
70855
119797
107542
156634
102946
60567
226326
102946
60567
50760
138346
116081
80184
233603
226326
131160
24
3
3
3
4
26
8
13
19
68
30
28
25
28
2
8
6
6
17
5
28
28
19
8
3
9
3
18
50
11
46
22
10
111
10
15
4
15
52
5
57
119
38
28
3
3
3
4
30
8
13
20
78
33
41
40
31
2
9
6
6
18
5
41
41
20
8
4
11
3
22
72
11
58
26
11
172
10
18
7
15
69
5
66
194
51
88
3
3
3
4
44
8
23
38
99
42
122
228
43
2
9
8
8
25
5
122
122
31
49
174
63
5
56
328
11
181
34
13
2414
10
41
29
21
255
6
435
3095
99
47.20%
6.42%
6.77%
4.71%
3.84%
32.80%
11.50%
28.00%
17.70%
43.10%
33.70%
49.80%
48.90%
34.30%
5.46%
10.50%
16.60%
16.60%
20.40%
7.64%
49.80%
49.80%
21.40%
11.40%
16.80%
26.10%
11.60%
37.30%
48.80%
15.40%
39.90%
41.70%
24.30%
50.00%
22.60%
33.00%
15.10%
13.60%
53.00%
8.81%
39.20%
51.60%
40.60%
APSPATAVHALASAFGPLLLR
APVDFGYVGIDSILEQMR
APVPTGEVYFADSFDR
AQALAIETEAELER
AQDGSNPLSLQDLIEK
AQEELAGLKR
AQEIEAATLAGR
AQFEGIVTDLIK
AQGYSGLSVK
AQHELEEAEER
AQHEQYVAEAEEK
AQHVQVEEGSEPDGFWEALGGK
AQKDEEKMEIQEIQLK
AQLEEQASQHR
AQLGVQAFADALLIIPK
AQLHDTNMELTDLK
AQLIMQAEAEAESVR
AQQVAVQEQEIAR
AQQVSQGLDVLTAK
AQSLEPYGAGLK
AQVHVSEEGSEPEAMLQVLGPK
AQVHVSEEGSEPEAMLQVLGPKPDLPQGTEDTAK
AQVSALENK
AQYDDIASR
AQYEDIANR
AQYEEIAKR
AQYEEIALK
ARFEELNADLFR
ASALGSDGVR
ASAPVPVPSGPSEELLR
ASESISLK
ASFNHFDR
ASGDKEAEGAPQVEAGK
ASIAALEAK
ASIHEAWTDGK
ASKPMKPAASDLPVPAEGVR
ASLENSLEETK
ASNLENSTYDLYTIPK
ASQLIK
ASQVATGIR
ASRDEIFAQSK
ASREEILAQAK
ASSDGEGTMSRPASVDGSPVSPSTNR
R
K
K
K
K
R
R
R
R
K
K
R
R
R
R
K
K
R
K
R
R
R
R
K
K
K
R
R
R
R
K
R
R
K
K
K
K
R
R
K
R
R
R
A
R
G
V
V
C
L
R
V
A
L
T
E
L
V
L
M
R
V
A
P
E
C
S
S
S
S
G
V
Q
N
D
R
I
E
N
G
D
T
D
E
E
T
76.5
68.4
75.9
72.2
71.9
59.5
62.3
60.7
33.5
47.9
63.3
25.4
75.5
65.7
58.3
59.3
102
65.4
55.2
41.4
26.1
67.5
44
52.5
43.8
33.7
31.5
54.7
60.3
27.4
62.1
32
70.6
75.3
36.5
40.9
68.2
64.3
28.1
43.9
41.9
60.4
60
19.7
29.2
29.8
28.1
28.8
27.2
28.2
26.9
27.9
29
29.4
31.2
29.5
29.1
20.2
30.1
29.8
27.7
25.9
28.4
29.6
29.6
26.6
25.6
27.6
28
27.3
29.2
27.2
27
26.6
25.8
29.3
26.8
28.1
27.3
28.5
29.7
26.1
26.8
28.7
27.3
31.5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
687.3976
1,013.50
885.9257
772.4052
864.4486
557.8145
615.3281
667.3731
505.2713
670.8099
766.3541
790.7092
988.506
648.819
884.5272
822.9008
831.4152
735.39
729.403
617.33
784.3937
1,201.93
480.2622
519.7463
540.2562
554.294
532.7846
494.2568
466.7441
853.4638
417.7323
497.2315
822.3986
437.2566
607.796
679.6976
610.8046
914.9556
659.4099
451.7575
626.3211
608.3391
855.725
2,059.17
2,024.99
1,769.84
1,542.79
1,726.88
1,113.61
1,228.64
1,332.73
1,008.53
1,339.60
1,530.69
2,369.10
1,975.00
1,295.62
1,767.04
1,643.79
1,660.81
1,468.76
1,456.79
1,232.64
2,350.16
3,602.77
958.5087
1,037.48
1,078.50
1,106.57
1,063.55
1,479.75
931.4726
1,704.91
833.449
992.4474
1,642.78
872.4976
1,213.58
2,036.07
1,219.59
1,827.90
658.402
901.4994
1,250.63
1,214.66
2,564.15
2,060.17
2,026.00
1,770.83
1,543.80
1,727.88
1,114.62
1,229.65
1,333.74
1,009.53
1,340.61
1,531.70
2,370.10
1,976.00
1,296.63
1,768.04
1,644.79
1,661.82
1,469.77
1,457.80
1,233.65
2,351.16
3,603.75
959.5162
1,038.49
1,079.51
1,107.58
1,064.56
1,480.75
932.4802
1,705.91
834.4572
993.4542
1,643.79
873.5046
1,214.58
2,037.08
1,220.60
1,828.90
659.4093
902.5059
1,251.63
1,215.67
2,565.15
3
2
2
2
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
3
3
2
2
2
2
2
3
2
2
2
2
2
2
2
3
2
2
1
2
2
2
3
5.41
2.67
5.47
3.66
4.33
0.84
0.57
1.04
3.00
2.76
1.65
4.91
1.44
0.41
5.13
2.03
3.40
0.69
1.11
3.30
4.33
8.38
0.29
0.79
7.09
0.25
1.57
0.14
0.30
4.17
0.47
1.08
0.99
0.95
2.95
1.60
0.33
3.43
0.89
1.46
0.71
0.43
4.25
236
263
63
758
708
828
120
349
1055
1900
402
576
134
671
433
950
303
262
353
318
205
205
817
278
317
328
307
300
5
277
877
753
257
1808
403
429
344
383
785
190
1703
1660
323
256
280
78
771
723
837
131
360
1064
1910
414
597
149
681
449
963
317
274
366
329
226
238
825
286
325
336
315
311
14
293
884
760
273
1816
413
448
354
398
790
198
1713
1670
348
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M2:Oxidation(+15.99)
M17:Oxidation(+15.99)
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
M5:Oxidation(+15.99)
M15:Oxidation(+15.99)
M15:Oxidation(+15.99)
M5:Oxidation(+15.99)
Insulinreceptorsubstrate1
IPI00199662
131160
38
51
99
40.60%
ASSDGEGTMSRPASVDGSPVSPSTNR
R
T
47.7
31.1
2
IPI00199662
131160
27
34
85
32.00%
ASSDGEGTMSRPASVDGSPVSPSTNR
R
T
43
30.6
2
Insulinreceptorsubstrate1
Ribophorin1
TypeIIkeratinKb23
TypeIIkeratinKb23
TypeIIkeratinKb25
TypeIIkeratinKb25
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
PolymeraseIandtranscriptreleasefactor
PolymeraseIandtranscriptreleasefactor
LMO7b
Coatomersubunitgamma
Isoform1ofFibronectin
234kDaprotein
Myosin3
111kDaprotein
Alphaactinin1
Keratin,typeIcytoskeletal17
IPI00199662
IPI00204365
IPI00454476,IPI00780672
IPI00454476,IPI00780672
IPI00200792,IPI00421785
IPI00200792,IPI00421785
IPI00187731
IPI00187731
IPI00201300
IPI00201300
IPI00421345
IPI00780394
IPI00200757,IPI00231982,IPI00231983
IPI00391300
IPI00201578
IPI00476704
IPI00209082,IPI00454431
IPI00370073
131160
68384
62207
62207
55803
55803
32941
32941
43891
43891
156634
98515
272486
233603
223846
111364
102946
48106
30
4
11
7
2
2
3
3
2
4
21
9
8
70
68
28
22
20
42
5
14
8
2
2
4
3
2
4
24
9
9
82
78
31
26
27
108
5
39
16
2
2
12
8
2
4
95
10
12
145
99
43
34
386
29.50%
11.20%
13.30%
9.73%
11.80%
11.80%
60.20%
63.00%
8.42%
15.80%
19.80%
12.90%
4.68%
45.50%
43.10%
34.30%
41.70%
43.40%
ASSDGEGTMSRPASVDGSPVSPSTNR
ASSFVLALEPELESR
ATAENEFVALK
ATAENEFVALKK
ATAENEFVVLK
ATAENEFVVLKK
ATDAEADVASLNR
ATDAEADVASLNRR
ATEEPSGTGSDELIK
ATEMVEVGPDDDEVGAER
ATFSSTSGLDSVSDSGEGR
ATFYLNVLEQK
ATGVFTTLQPLR
ATISALEAK
ATLEQTER
ATLNSGPGAQQK
ATLPDADKER
ATMQNLNDR
R
R
R
R
R
R
K
K
R
K
K
R
K
K
R
K
K
K
T
L
K
D
K
D
R
I
S
G
S
Q
S
I
A
E
L
L
46.6
69.7
79.3
75.2
67.3
55
105
44
71.5
111
108
50.7
52.5
55.2
59.3
48.7
55.9
52.9
30.6
27.8
27.4
27.3
27.5
26.1
28.8
29
29.4
29.7
29.7
26.5
25.3
26.4
28.2
27.6
27.8
27.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
M9:Oxidation(+15.99)
M9:Oxidation(+15.99),S21:
Phospho(+79.97)
882.382
S2:Phospho(+79.97),M9:
Oxidation(+15.99)
882.3776
S3:Phospho(+79.97),M9:
Oxidation(+15.99)
882.3771
824.4373
596.8146
660.8624
610.8303
450.2544
666.8243
744.8754
767.3679
M4:Oxidation(+15.99)
967.9193
930.4188
663.3618
652.3757
452.2623
474.245
586.3071
558.2896
M3:Oxidation(+15.99)
539.7517
Agap3
Mrlc2
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
58223
MyosinregulatorylightchainMRLC2
IPI00421625,IPI00564409,IPI00914162 19821
Isoform2ofPhosphatidylinositolbindingclathrinassembly IPI00194958,IPI00194959,IPI00471607,I
protein
PI00565441
64640
CytospinA
IPI00372846
124324
Insulinreceptorsubstrate1
IPI00199662
131160
NADHubiquinoneoxidoreductase75kDasubunit,
mitochondrial
IPI00358033
79396
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
Vinculin
IPI00365286
116599
Tcomplexprotein1subunitgamma
IPI00372388
60630
MyosinIc
IPI00393867
119797
82kDaprotein
IPI00364895,IPI00566985
82231
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
Actin,alphaskeletalmuscle
IPI00189813
42034
Actin,alphaskeletalmuscle
IPI00189813
42034
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
Tubulinalpha1Bchain
IPI00339167
50134
234kDaprotein
IPI00391300
233603
26SproteasomenonATPaseregulatorysubunit2
IPI00370456
100172
Isoform1ofNexilin
IPI00209938
78377
Isoform1ofNexilin
IPI00209938
78377
Isoform1ofNexilin
IPI00209938
78377
similartodesmoplakinisoformIisoform2
IPI00366081
332383
10
3
13
4
26
5
21.40%
22.70%
ATPSTAPGTSPR
ATSNVFAMFDQSQIQEFK
R
R
G
E
81.7
83.5
27.3
30.4
2
2
M8:Oxidation(+15.99)
2
14
28
2
16
39
2
20
93
5.36%
16.30%
31.30%
ATTLSNAVSSLASTGLSLTK
ATVASDQIEMNR
ATWQESGGVELGR
R
K
R
V
L
V
95.7
57.8
79.6
24.5
28.9
29.1
2
2
2
2
12
9
17
2
42
2
8
2
2
9
8
58
3
19
19
20
18
2
12
9
18
2
59
2
8
3
3
9
11
67
3
22
22
26
18
2
12
11
25
2
381
2
11
8
12
11
30
363
3
61
61
63
28
4.81%
12.40%
12.10%
20.40%
4.04%
43.80%
3.51%
18.10%
52.80%
53.60%
12.10%
26.80%
40.00%
4.63%
25.80%
25.80%
26.80%
7.79%
AVAAIAGGLVDAEALVALK
AVAALLTIPEAEK
AVAGDASESALLK
AVAGNISDPGLQK
AVAQALEVIPR
AVASEIFK
AVDEAADALLK
AVDSLVPIGR
AVFPSIVGR
AVFPSIVGRPR
AVFQANQENLPILK
AVFVDLEPTVIDEVR
AVIYNPATQADWTAK
AVPLALALISVSNPR
AVSQESLTPGK
AVSQESLTPGK
AVSQESLTPGKLEINFEQLLR
AVTGYNDPETGNIISLFQAMNK
K
R
R
K
R
K
K
K
R
R
R
R
R
R
K
K
K
R
D
S
C
S
T
G
A
G
P
H
R
T
K
L
L
L
Q
E
87.2
57.8
69.5
68.3
72.4
33.8
44.9
57.8
65.8
74.7
27.4
76.6
65.9
33.8
42.7
52.6
54.3
81
17.9
22.4
28.1
27.5
21.6
24.5
28.2
22.8
25.8
24.2
25.9
27
29.1
16.1
28.9
28.6
28.9
30
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
8
4
9
4
9
38
6
13
11
4
9
4
9
44
6
21
42
4
10
5
9
150
6
430
17.70%
16.10%
9.01%
6.29%
7.99%
29.70%
8.26%
21.50%
AVVEDDLR
AVVYSNTIQSIMAIVK
AYEFAER
AYLPVNESFGFTADLR
AYVDDTPADEMK
DAAGLESQLQDTQELLQEETR
DADSIHQYLLQR
DAEAWFNEK
R
R
R
K
K
K
R
K
L
A
C
S
A
Q
K
S
50.1
96.5
32.2
69.8
45
105
38.5
57.8
26.7
25.1
26.8
29
28.2
30.8
28.1
26.3
2
2
2
2
2
2
2
2
13
24
76
33.90%
DAEDGPVEDSKPK
R
P
87.4
29
2
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
58223
GuaninenucleotidebindingproteinG(i),alpha2subunit IPI00231925
40482
Clathrinheavychain1
IPI00193983
191585
Elongationfactor2
IPI00203214
95268
170kDaprotein
IPI00421357,IPI00476855
170072
234kDaprotein
IPI00391300
233603
aminopeptidasepuromycinsensitive
IPI00372700
103329
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
56489
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
M10:Oxidation(+15.99)
S3:Phospho(+79.97)
S3:Phospho(+79.97)
M20:Oxidation(+15.99)
M12:Oxidation(+15.99)
M11:Oxidation(+15.99)
2,644.12
2,645.11
3
5.88
323
348
IPI00391300
IPI00391300
IPI00210566
IPI00768956
IPI00393340
IPI00765011,IPI00189819,IPI00896224
IPI00777179,IPI00231615
IPI00475639
IPI00213463
IPI00213463
IPI00209938
IPI00558912
IPI00370090
IPI00558912
TRUE
TRUE
6.70%
14
99
Insulinreceptorsubstrate1
Tnnt2
2.08
3.86
7
5
51
Irs1
Rpn1
Kb23
Kb23
Krt85
Krt85
Tpm2
Tpm2
Ptrf
Ptrf
Lmo7
Copg
Fn1
Myh10
Myh3
Clip2
Actn1
Krt17
Agap3
Gnai2
Cltc
Eef2
Eprs
Myh10
Npepps
Krt10
2
2
5
4
38
Irs1
Ndufs1
Cand1
Atp1a1
Vcl
Cct3
Myo1c
Immt
Atp5a1
Acta1
Acta1
Atp1a1
Tuba1b
Myh10
Psmd2
Nexn
Nexn
Nexn
Dsp
1,775.81
1,591.75
5
32941
131160
Irs1
Picalm
Specc1l
Irs1
1,774.81
1,590.75
OtherProteins
IPI00230775
IPI00197888
IPI00382153
IPI00213463
TRUE
2,644.11
2,645.11
3
0.89
323
348
TRUE
2,644.11
1,646.86
1,191.61
1,319.71
1,219.65
1,347.74
1,331.63
1,487.74
1,532.72
1,933.82
1,858.82
1,324.71
1,302.74
902.509
946.4744
1,170.60
1,114.56
1,077.49
2,645.11
1,647.86
1,192.62
1,320.72
1,220.65
1,348.75
1,332.64
1,488.74
1,533.73
1,934.83
1,859.83
1,325.71
1,303.74
903.5152
947.4799
1,171.61
1,115.57
1,078.50
3
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
2
0.34
4.54
0.03
0.49
0.13
0.15
1.04
1.58
0.37
0.90
2.12
3.90
4.71
1.80
2.42
0.70
1.35
0.37
323
65
200
200
219
219
78
78
33
340
699
537
1077
1851
1691
599
556
86
348
79
210
211
229
230
90
91
47
357
717
547
1088
1859
1698
610
565
94
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
571.7949
1,054.00
1,141.57
2,105.99
1,142.58
2,106.98
2
2
1.21
5.87
98
18
109
35
961.5333
675.8196
695.3417
1,921.05
1,349.62
1,388.67
1,922.04
1,350.63
1,389.68
2
2
2
7.32
0.60
0.50
299
568
950
318
579
962
TRUE
TRUE
TRUE
876.5214
663.3897
616.3326
635.3438
583.8494
432.7456
558.3023
513.801
473.281
599.8568
792.9445
851.4592
824.9219
760.9663
598.7827
558.7991
818.0917
1,200.09
1,751.03
1,324.76
1,230.65
1,268.67
1,165.68
863.4756
1,114.59
1,025.59
944.5463
1,197.70
1,583.87
1,700.90
1,647.83
1,519.92
1,195.55
1,115.58
2,451.25
2,398.16
1,752.03
1,325.77
1,231.65
1,269.68
1,166.69
864.4831
1,115.60
1,026.59
945.5522
1,198.71
1,584.88
1,701.91
1,648.83
1,520.92
1,196.56
1,116.59
2,452.25
2,399.16
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
3
2
4.41
2.61
3.20
0.64
0.97
0.40
1.46
0.80
1.98
0.27
3.80
2.53
1.50
5.40
0.85
0.25
4.35
5.77
337
1179
446
803
439
856
275
195
31
31
431
65
56
689
343
343
343
2342
355
1191
458
815
449
863
285
204
39
41
444
79
70
703
353
353
363
2363
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
458.7409
876.9854
443.2098
900.4542
685.7957
1,187.58
729.8734
555.2495
915.4661
1,751.96
884.4039
1,798.89
1,369.58
2,373.14
1,457.73
1,108.48
916.4741
1,752.96
885.4106
1,799.90
1,370.58
2,374.14
1,458.73
1,109.49
2
2
2
2
2
2
2
2
0.23
3.50
1.21
1.99
3.50
2.33
3.21
0.69
419
71
1095
786
289
1346
902
334
426
86
1101
801
300
1366
913
342
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
693.8237
1,385.63
1,386.64
2
0.29
55
67
TRUE
IPI00207038
IPI00197888,IPI00210945,IPI00230775
IPI00197888,IPI00210945,IPI00230775
IPI00765011,IPI00189819,IPI00896224
IPI00765011,IPI00189819,IPI00896224
Tnnt2
Krt17
Krt42
Hspa9
Hspa8
Hspa5
Eif3c
Clip2
Anxa2
Rrbp1
Cltc
Tpm1
Tpm2
Tpm2
Eno1
DCD
Mprip
Thbs1
Isoform2ofTroponinT,cardiacmuscle
Keratin,typeIcytoskeletal17
Keratin,typeIcytoskeletal42
Stress70protein,mitochondrial
Heatshockcognate71kDaprotein
78kDaglucoseregulatedprotein
Eukaryotictranslationinitiationfactor3subunitC
111kDaprotein
IsoformShortofAnnexinA2
similartoRibosomebindingprotein1
Clathrinheavychain1
tropomyosin1,alphaisoformc
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
Alphaenolase
Dermcidin
258kDaprotein
Thrombospondin1
NADHubiquinoneoxidoreductase75kDasubunit,
mitochondrial
Alphaactinin1
tropomyosin1,alphaisoformc
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00370073
48106
IPI00421791
50196
IPI00363265
73840
IPI00208205
70855
IPI00206624
72331
IPI00914189
105420
IPI00476704
111364
IPI00325146
38662
IPI00188079
143655
IPI00193983
191585
IPI00210945
32831
IPI00187731
32941
IPI00187731
32941
IPI00464815,IPI00767147
47111
IPI00421832
11266
IPI00392930
257845
IPI00422076
129653
10
22
2
9
16
21
6
29
3
12
27
35
3
5
2
4
35
19
17
33
3
9
19
27
6
34
3
12
29
57
4
6
2
6
51
20
45
468
19
11
59
59
6
49
6
15
29
309
12
13
2
61
95
38
30.40%
41.10%
21.20%
18.90%
33.30%
39.60%
8.89%
32.40%
9.14%
10.90%
21.50%
70.80%
64.80%
71.80%
8.53%
35.50%
18.00%
17.70%
DAEDGPVEDSKPKPSR
DAEDWFFSK
DAEEWFFTK
DAGQISGLNVLR
DAGTIAGLNVLR
DAGTIAGLNVMR
DAHNALLDIQSSGR
DALDQAQQVER
DALNIETAIK
DALNQATSQVESK
DAMQYASESK
DAQEKLELAEK
DAQEKLEQAEK
DAQEKLEQAEKK
DATNVGDEGGFAPNILENK
DAVEDLESVGK
DAYELEVLLR
DDDYAGFVFGYQSSSR
R
K
K
K
K
K
K
R
R
R
K
K
K
K
K
K
K
R
L
T
T
V
I
I
A
L
T
Q
D
K
K
A
E
G
V
F
75.9
60.1
60.9
70.6
88.1
76.6
42
88.2
51.8
72.7
58.4
57.7
59.1
44.6
68.3
67.4
74.6
85.6
29.8
27.5
28.3
26.9
27.3
28
29
28.8
27.8
29.1
26.8
28.7
28.9
28.4
30.3
28.5
27.5
29.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
M11:Oxidation(+15.99)
M3:Oxidation(+15.99)
863.9177
572.752
586.7678
621.8445
600.3417
617.3173
748.8787
636.8131
544.3057
695.8469
573.2459
637.3362
644.8231
708.8709
980.97
581.2867
610.8319
907.3908
1,725.82
1,143.49
1,171.52
1,241.67
1,198.67
1,232.62
1,495.74
1,271.61
1,086.60
1,389.68
1,144.48
1,272.66
1,287.63
1,415.73
1,959.92
1,160.56
1,219.65
1,812.77
1,726.83
1,144.50
1,172.53
1,242.68
1,199.68
1,233.63
1,496.75
1,272.62
1,087.60
1,390.68
1,145.48
1,273.66
1,288.64
1,416.73
1,960.93
1,161.56
1,220.65
1,813.77
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1.44
0.78
1.18
0.42
0.54
0.43
2.55
0.16
3.18
3.28
4.83
0.41
0.16
0.20
3.51
1.40
2.53
3.72
55
270
280
207
160
186
626
965
38
731
1536
66
66
66
203
86
2134
1019
70
278
288
218
171
197
639
975
47
743
1545
76
76
77
221
96
2143
1034
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
IPI00358033
IPI00209082,IPI00454431
IPI00210945
79396
102946
32831
2
16
33
2
19
59
2
32
252
4.81%
35.10%
65.10%
DDGAAILAAVSSIAQK
DDPLTNLNTAFDVAER
DEEKMEIQEIQLK
R
K
K
I
Y
E
40.1
90
74.7
27.3
29.5
29.9
2
2
2
1,529.82
1,790.86
1,648.81
2
2
2
4.97
3.77
0.84
484
199
137
499
214
149
TRUE
TRUE
TRUE
IPI00187731
IPI00199662
IPI00209113
IPI00197553,IPI00230893,IPI00778173
IPI00212844
IPI00776774
IPI00914189
IPI00201578
IPI00209113
IPI00557294
IPI00365982
IPI00844828
IPI00923716
IPI00393867
IPI00213463
IPI00230941
32941
131160
226326
32542
55719
173996
105420
223846
226326
52762
63529
137936
80911
119797
104900
53716
5
33
123
2
6
4
6
47
122
3
6
13
17
42
26
29
6
45
194
3
8
4
6
50
194
3
7
13
22
59
29
39
13
88
2027
3
16
8
6
182
2067
3
11
13
52
381
46
105
71.80%
36.00%
52.30%
13.70%
16.00%
3.23%
8.89%
31.50%
51.90%
11.30%
18.40%
14.40%
37.80%
43.80%
40.80%
67.20%
DEEKMELQEMQLK
DEHFAIAADSEAEQDSWYQALLQLHNR
DELADEIANSSGK
DELHIVEAEAMNYEGSPIK
DEVAHTLTENR
DEVMGDNLLLSSVFQFSR
DFESHITNYK
DFEYSQLQSK
DFSALESQLQDTQELLQEENR
DFSEAPSFTQPLADR
DFTSLENTVEER
DGEAGAQGAPGPAGPAGER
DGGQTTPASTR
DGIIDFTSGSELLITK
DGLAFNALIHR
DGQVINETSQHHDDLE
K
R
R
K
K
R
R
K
K
R
R
K
R
R
K
R
E
A
G
V
V
K
Q
V
Q
T
L
G
L
A
H
63.2
66
99.4
51
40.4
77.5
39.7
52.5
102
66.9
48.3
86.6
50.2
105
49
71.7
30.1
31
28.8
31.1
28.8
29.9
28.7
28.8
30.9
29.7
29.1
29.5
27.7
27.5
27.2
30.3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
765.4166
895.9354
M5:Oxidation(+15.99)
824.9099
M5:Oxidation(+15.99),M10:
Oxidation(+15.99)
841.8859
1,053.16
674.8159
M11:Oxidation(+15.99)
721.0125
642.8146
M4:Oxidation(+15.99)
1,037.00
627.296
622.7938
1,247.09
840.8983
720.3386
832.8895
545.7615
854.9553
613.8359
918.9041
1,528.82
1,789.86
1,647.80
1,681.76
3,156.47
1,347.62
2,160.01
1,283.61
2,071.99
1,252.58
1,243.57
2,492.17
1,679.78
1,438.66
1,663.76
1,089.51
1,707.89
1,225.66
1,835.79
1,682.76
3,157.46
1,348.62
2,161.01
1,284.62
2,073.00
1,253.58
1,244.58
2,493.17
1,680.79
1,439.67
1,664.76
1,090.51
1,708.90
1,226.66
1,836.80
2
3
2
3
2
2
2
2
2
2
2
2
2
2
2
2
1.26
5.31
0.48
4.25
2.31
2.43
3.05
0.07
0.26
0.97
2.66
4.86
2.05
0.81
0.47
0.15
137
90
1705
55
190
1400
151
1085
1302
385
208
602
503
1013
194
451
149
116
1717
73
200
1417
160
1094
1322
399
219
620
513
1028
204
466
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00554334
IPI00213463
IPI00391300
IPI00209082,IPI00454431
IPI00201578
IPI00207989
IPI00207988,IPI00388110
81251
104900
233603
102946
223846
116081
126813
27
28
49
22
69
52
2
33
34
53
26
76
69
2
100
49
157
34
172
255
2
50.10%
39.60%
33.40%
41.70%
42.20%
53.00%
3.61%
DGTFLIR
DHALLEEQSK
DHNIPGELER
DHSGTLGPEEFK
DIDDLELTLAK
DIIDKQHTEQEASYGR
DIILQSNPLLEAFGNAK
R
R
K
R
K
R
K
E
Q
Q
A
V
D
T
38
46.5
32.8
53.4
65.6
43.7
87.6
26.3
28.9
28.3
28.8
28
30.4
26.1
2
2
2
2
2
2
2
411.2301
585.294
590.2929
658.8102
623.3328
630.6382
922.0065
820.4446
1,168.57
1,178.57
1,315.60
1,244.65
1,888.89
1,842.00
821.4524
1,169.58
1,179.58
1,316.61
1,245.66
1,889.90
1,843.00
2
2
2
2
2
3
2
0.12
0.18
1.69
0.21
0.36
0.37
4.66
635
634
244
761
954
325
144
641
643
253
772
964
340
160
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Nedd4
Capza2
Tra1
Anxa1
Mprip
Isoform2ofTropomyosinbetachain
Insulinreceptorsubstrate1
Myosin9
IsoformB23.1ofNucleophosmin
RACalphaserine/threonineproteinkinase
174kDaprotein
Eukaryotictranslationinitiationfactor3subunitC
Myosin3
Myosin9
53kDaprotein
cytoskeletonassociatedprotein4
collagen,type1,alpha1
Isoform2ofGelsolin
MyosinIc
Alphaactinin4
Vimentin
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
Alphaactinin4
234kDaprotein
Alphaactinin1
Myosin3
MyosinId
MyosinIe
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
Factincappingproteinsubunitalpha2
Isoform1ofEndoplasmin
AnnexinA1
258kDaprotein
IPI00876592
IPI00370681
IPI00365985
IPI00231615,IPI00777179
IPI00392930
102739
32949
92756
38813
257845
11
4
9
3
40
11
4
9
3
54
12
6
9
3
117
19.00%
23.40%
16.70%
12.40%
19.90%
DILGASDPYVR
DIQDSLTVSNEVQTAK
DISTNYYASQK
DITSDTSGDFR
DIYTELSIAK
K
K
K
K
K
V
E
K
N
A
28.9
89.7
53.5
58.7
49.8
28.7
28.9
28.8
27.2
27.9
2
2
2
2
2
1,205.62
1,747.87
1,289.60
1,213.53
1,152.62
2
2
2
2
2
2.87
4.56
2.87
0.23
0.46
94
211
672
167
2179
104
226
682
177
2188
TRUE
TRUE
TRUE
TRUE
TRUE
111kDaprotein
LlactatedehydrogenaseAchain
Kinesin1heavychain
Tropomodulin1
Myosin9
234kDaprotein
Myosin3
Myosin9
29
3
13
4
111
58
76
113
34
3
13
5
172
67
92
179
49
4
13
5
2414
363
323
1862
32.40%
10.50%
17.30%
15.00%
50.00%
40.00%
46.50%
50.90%
DKEVAALTSQMDMLR
DLADELALVDVIEDK
DLAEIGIAVGNNDVK
DLDEDEILGALTEEELR
DLEAHIDTANK
DLEAQIEAANK
DLEEATLQHEATVATLR
DLEGLSQR
R
K
K
R
K
K
R
K
A
L
Q
T
N
A
K
L
53.4
92.5
60.5
79.3
69.9
68.5
104
54.7
29.4
28.5
27.4
30.6
28.4
28.3
28.4
25.9
2
2
2
2
2
2
2
2
1,738.83
1,656.85
1,526.80
1,958.94
1,225.59
1,200.60
1,895.97
916.4609
1,739.83
1,657.85
1,527.80
1,959.94
1,226.60
1,201.61
1,896.97
917.4693
2
2
2
2
2
2
2
2
1.71
2.82
4.74
4.50
0.53
0.27
3.24
0.69
802
43
561
12
1622
1665
1178
1394
816
57
575
28
1632
1675
1194
1401
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Syncrip
Tmod3
Myh9
Myh9
Lmo7
Ddx3x
70kDaprotein
Tropomodulin3
Myosin9
Myosin9
LMO7b
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked
IPI00476704
111364
IPI00197711
36433
IPI00364904
109514
IPI00189723,IPI00421889
40464
IPI00209113
226326
IPI00391300
233603
IPI00201578
223846
IPI00209113
226326
IPI00557424,IPI00764064,IPI00776515,I
PI00782066
69603
IPI00373505
39455
IPI00209113
226326
IPI00209113
226326
IPI00421345
156634
IPI00362534
73130
603.314
874.4437
645.3065
607.2709
576.8118
M11:Oxidation(+15.99),M13:
Oxidation(+15.99)
870.4208
829.4332
764.4085
980.4785
613.8051
601.307
948.9904
459.2383
1,204.61
1,746.87
1,288.60
1,212.53
1,151.61
Clip2
Ldha
Kif5b
Tmod1
Myh9
Myh10
Myh3
Myh9
3
4
138
132
45
6
3
6
222
196
54
6
3
9
3511
883
120
15
5.78%
17.60%
55.70%
55.20%
37.60%
10.60%
DLFEDELVPLFEK
DLGDYKDLDEDELLGK
DLGEELEALK
DLGEELEALKTELEDTLDSTAAQQELR
DLGGSSSGAEVR
DLLDLLVEAK
R
K
R
R
R
K
A
L
T
S
I
Q
74.1
75.9
70.4
73
78.4
63.2
29.4
30.1
28
29.8
27.6
25.8
2
2
2
2
2
2
797.4086
919.4423
558.7935
755.1295
567.7733
564.8309
1,592.80
1,836.87
1,115.57
3,016.49
1,133.53
1,127.65
1,593.81
1,837.87
1,116.58
3,017.48
1,134.54
1,128.65
2
2
2
4
2
2
2.47
3.01
0.14
4.58
0.29
1.87
172
8
1136
1136
1361
555
184
23
1145
1162
1372
564
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Tnnt3
Isoform1ofTroponinT,fastskeletalmuscle
952.4658
1,902.92
1,903.92
2
0.66
68
83
TRUE
Tnnt2
Hnrnpu
Fn1
Myh9
Copb1
Myo1c
Myh10
Acta1
Acta1
Actc1
Acta1
971.4887
511.2893
646.8425
717.3306
634.8267
454.7459
1,021.18
507.7442
813.9257
1,122.54
754.6796
1,940.96
1,020.56
1,291.67
1,432.65
1,267.64
907.4761
3,060.52
1,013.47
1,625.84
2,243.06
2,261.02
1,941.97
1,021.57
1,292.67
1,433.65
1,268.64
908.4842
3,061.51
1,014.48
1,626.84
2,244.06
2,262.02
2
2
2
2
2
2
3
2
2
2
3
1.28
2.37
2.58
1.73
5.23
0.36
6.27
1.41
1.22
1.81
2.55
100
601
911
1573
108
73
1180
186
186
294
294
115
609
921
1584
117
79
1206
193
198
314
314
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
1,139.51
1,116.04
1,108.05
2,277.00
2,230.06
2,214.08
2,278.01
2,231.07
2,215.07
2
2
2
2.18
1.24
7.24
294
292
292
314
312
312
TRUE
TRUE
TRUE
718.7781
726.833
967.5156
546.7537
701.8472
669.3104
653.8416
877.4623
538.2628
1,186.07
1,435.54
1,451.65
1,933.02
1,091.49
1,401.68
1,336.61
1,305.67
1,752.91
1,074.51
2,370.12
1,436.55
1,452.65
1,934.01
1,092.50
1,402.68
1,337.61
1,306.68
1,753.91
1,075.52
2,371.12
2
2
2
2
2
2
2
2
2
2
0.82
3.56
4.75
0.08
3.68
3.31
0.25
4.75
0.38
5.11
317
672
475
176
82
154
393
49
867
347
327
683
492
184
94
165
404
64
875
368
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
644.819
683.32
709.3207
961.491
846.3953
615.7841
1,287.62
1,364.62
1,416.63
1,920.97
845.3875
1,229.55
1,288.63
1,365.63
1,417.63
1,921.97
846.396
1,230.56
2
2
2
2
1
2
2.11
0.12
4.59
4.15
0.75
0.03
538
114
1466
295
203
1176
548
127
1479
310
209
1186
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
772.8507
528.3297
493.7678
543.8012
618.306
579.2434
1,543.69
1,054.64
985.52
1,085.59
1,234.60
1,156.47
1,544.69
1,055.65
986.5273
1,086.59
1,235.60
1,157.48
2
2
2
2
2
2
4.21
4.66
0.53
0.41
1.81
0.35
82
6
476
914
501
280
94
14
483
922
511
288
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Ndufs1
Actn1
Tpm1
Tpm2
Irs1
Myh9
Npm1
Akt1
Kab
Eif3c
Myh3
Myh9
Mybph
Ckap4
Col1a1
Gsn
Myo1c
Actn4
Vim
Pik3r2
Actn4
Myh10
Actn1
Myh3
Myo1d
Myo1e
6
9
25
25.10%
DLMELQALIDSHFEAR
K
K
91.1
29.7
2
Isoform2ofTroponinT,cardiacmuscle
SP120
Isoform1ofFibronectin
Myosin9
Coatomersubunitbeta
MyosinIc
234kDaprotein
Actin,alphaskeletalmuscle
Actin,alphaskeletalmuscle
Actin,alphacardiacmuscle1
Actin,alphaskeletalmuscle
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00210090,IPI00566967
87731
IPI00200757,IPI00231982,IPI00231983 272486
IPI00209113
226326
IPI00211812
106996
IPI00393867
119797
IPI00391300
233603
IPI00189813
42034
IPI00189813
42034
IPI00194087
42002
IPI00189813
42034
17
5
8
138
14
42
70
2
2
21
2
26
5
9
222
14
59
82
4
3
38
3
111
7
12
3511
15
381
145
23
10
537
8
43.90%
6.64%
4.68%
55.70%
20.80%
43.80%
45.50%
58.60%
53.60%
54.10%
52.80%
DLNELQTLIEAHFENR
DLPEHAVLK
DLQFVEVTDVK
DLQGRDEQSEEK
DLQHPNEFIR
DLQIYTR
DLSEELEALKTELEDTLDTTAAQQELR
DLTDYLMK
DLTDYLMKILTER
DLYANNVLSGGTTMYPGIADR
DLYANNVMSGGTTMYPGIADR
K
K
K
R
K
R
R
R
R
K
K
K
M
V
K
G
Q
T
I
G
M
M
110
27.8
44.4
37.9
28.3
47
40.2
48
68.1
125
54.5
29.6
26.3
27.5
29.5
28.2
26.1
29.6
26.2
27.7
30.8
31.1
2
2
2
2
2
2
2
2
2
2
2
Acta1
Actb
Actb
Actin,alphaskeletalmuscle
Actin,cytoplasmic1
Actin,cytoplasmic1
IPI00189813
42034
IPI00189819,IPI00765011,IPI00896224 41720
IPI00189819,IPI00765011,IPI00896224 41720
2
6
6
3
12
12
12
107
254
53.60%
55.50%
48.80%
DLYANNVMSGGTTMYPGIADR
DLYANTVLSGGTTMYPGIADR
DLYANTVLSGGTTMYPGIADR
K
K
K
M
M
M
107
125
97.4
30.2
30.5
29.9
2
2
2
Myh9
Atp1a1
Hspa5
Vim
Nes
Copb2
Serpinh1
Sdpr
Myo1c
Gsn
Myosin9
IPI00209113
226326
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
78kDaglucoseregulatedprotein
IPI00206624
72331
Vimentin
IPI00230941
53716
Isoform1ofNestin
IPI00194103
208776
Coatomersubunitbeta'
IPI00231953
102535
SerpinH1
IPI00204703
46501
Serumdeprivationresponseprotein
IPI00362416
46368
MyosinIc
IPI00393867
119797
Isoform2ofGelsolin
IPI00923716
80911
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
MyosinIc
IPI00393867
119797
170kDaprotein
IPI00421357,IPI00476855
170072
ATPsynthasesubunitbeta,mitochondrial
IPI00551812
56336
Myosin9
IPI00209113
226326
LMO7b
IPI00421345
156634
IPI00365944,IPI00392935,IPI00817070,I
Myosinlightpolypeptide6
PI00896236
16957
LlactatedehydrogenaseAchain
IPI00197711
36433
similartoleiomodin3
IPI00568699
57499
MyosinId
IPI00207989
116081
HeatshockproteinHSP90alpha
IPI00210566
84800
TypeIkeratinKA16
IPI00421793
50760
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Myosin9
IPI00209113
226326
collagen,type1,alpha1
IPI00844828
137936
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
elastinmicrofibrilinterfacer1
IPI00199867
107542
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
Isoform2ofGelsolin
IPI00923716
80911
Actin,alphaskeletalmuscle
IPI00189813
42034
Actin,alphaskeletalmuscle
IPI00189813
42034
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
83516
MyosinId
IPI00207989
116081
MyosinId
IPI00207989
116081
MyosinId
IPI00207989
116081
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Myosin3
IPI00201578
223846
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Copaprotein
IPI00372458
138346
TypeIIkeratinKb15
IPI00207038
58080
TypeIIkeratinKb15
IPI00207038
58080
Keratin,typeIIcytoskeletal6A
IPI00393340
59233
Keratin,typeIIcytoskeletal73
IPI00421780
60370
234kDaprotein
IPI00391300
233603
Isoform2ofAnkycorbin
IPI00372146
105981
Dermcidin
IPI00421832
11266
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
Tubulinalpha1Bchain
IPI00339167
50134
IPI00777201,IPI00778882,IPI00780661,I
33kDaprotein
PI00782724,IPI00869675
33027
similartokinectin1
IPI00563574
151567
Alphaactinin4
IPI00213463
104900
Alphaactinin1
IPI00209082,IPI00454431
102946
Collagenalpha2(I)chain
IPI00188921
129547
Phosphorylase
IPI00357945
96759
Keratin,typeIIcytoskeletal1
IPI00421857
64814
Keratin,typeIIcytoskeletal2epidermal
IPI00551558,IPI00559533
69273
Keratin,typeIcytoskeletal42
IPI00421791
50196
Trifunctionalenzymesubunitbeta,mitochondrial
IPI00198467
51398
GlutaminyltRNAsynthetase
IPI00362720
87683
Coatomersubunitbeta
IPI00211812
106996
Myosin9
IPI00209113
226326
Isoform1ofNexilin
IPI00209938
78377
smoothelin
IPI00361871,IPI00561311
99862
Isoform1ofEndoplasmin
IPI00365985
92756
IPI00365944,IPI00392935,IPI00817070,I
Myosinlightpolypeptide6
PI00896236
16957
Coatomersubunitbeta
IPI00211812
106996
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
Alphaactinin4
IPI00213463
104900
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
IPI00208989
122595
Tropomodulin3
IPI00373505
39455
Isoform2ofAnkycorbin
IPI00372146
105981
Isoform2ofAnkycorbin
IPI00372146
105981
Isoform2ofAnkycorbin
IPI00372146
105981
adaptorrelatedproteincomplex3,beta1subunit
IPI00360117
121486
258kDaprotein
IPI00392930
257845
IPI00777201,IPI00778882,IPI00780661,I
33kDaprotein
PI00782724,IPI00869675
33027
MyosinIc
IPI00393867
119797
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
258kDaprotein
IPI00392930
257845
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
IPI00876592
102739
LMO7b
IPI00421345
156634
Coatomersubunitbeta
IPI00211812
106996
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Keratin,typeIIcytoskeletal1b
IPI00454475
57238
HeatshockproteinHSP90beta
IPI00471584
83266
LMO7b
IPI00421345
156634
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Vimentin
IPI00230941
53716
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
TypeIIkeratinKb23
IPI00454476,IPI00780672
62207
Sodium/potassiumtransportingATPasesubunitbeta3 IPI00208061
31813
123
9
15
29
16
11
2
3
50
28
194
9
19
39
17
11
2
5
65
41
2027
11
32
105
27
12
2
8
289
122
52.30%
12.10%
28.70%
67.20%
10.50%
15.90%
6.47%
10.30%
48.90%
49.80%
DMFQETMEAMR
DMTSEELDDILR
DNHLLGTFDLTGIPPAPR
DNLAEDIMR
DNLAEELESVAGR
DNNQFASASLDR
DNQSGSLLFIGR
DNSQVNAVTVHTLLDK
DNYPQSVPR
DPDQTDGPGLSYLSSHIANVER
K
K
K
R
R
K
R
R
K
R
I
Y
G
L
C
T
L
L
L
V
54.1
58.3
60.1
43.7
87.3
67.8
42.1
98.7
75.6
66.4
25.9
28.8
27.4
27.1
29.7
28.5
28.2
27.8
27.6
30.9
2
2
2
2
2
2
2
2
2
2
Pik3ca
Myo1c
Eprs
Atp5b
Myh9
Lmo7
Myl6l
Ldha
Lmod3
Myo1d
Hsp90aa1
Krt16
Pik3r2
Myh9
Col1a1
Ddx3x
Hadha
Emilin1
Ddx3x
Gsn
Acta1
Acta1
Pik3r1
Myo1d
Myo1d
Myo1d
Pik3r2
Myh3
Hadha
Copa
Kb15
Kb15
LOC683313
Krt73
Myh10
Rai14
DCD
Myh9
Myh9
Tuba1b
Capza1
Ktn1
Actn4
Actn1
Col1a2
Pygb
Krt1
Krt2
Krt42
Hadhb
Qars
Copb1
Myh9
Nexn
Smtn
Tra1
Myl6l
Copb1
Pik3ca
Actn4
Pik3cb
Tmod3
Rai14
Rai14
Rai14
Ap3b1
Mprip
Capza1
Myo1c
Pik3ca
Atp5a1
Mprip
Nedd4
Lmo7
Copb1
Tpm2
Tpm2
Krt77
Hsp90ab1
Lmo7
Pik3r2
Vim
Tnnt2
Myh9
Myh9
Kb23
Atp1b3
Tpm1
Tpm2
Myh3
tropomyosin1,alphaisoformc
Isoform2ofTropomyosinbetachain
Myosin3
IPI00210945
IPI00187731
IPI00201578
32831
32941
223846
M3:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M14:Oxidation(+15.99)
M14:Oxidation(+15.99)
M8:Oxidation(+15.99),M14:
Oxidation(+15.99)
M14:Oxidation(+15.99)
M2:Oxidation(+15.99),M7:
Oxidation(+15.99),M10:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M8:Oxidation(+15.99)
10
40
9
2
111
46
10
51
9
3
172
58
12
216
9
7
2414
181
11.30%
43.40%
7.99%
5.48%
50.00%
39.90%
DPLSEITEQEK
DQAVMISGESGAGK
DQDVEPGAPSMGAK
DQEGQDVLLFIDNIFR
DQGELER
DQGPSEAELER
R
R
R
R
K
K
D
T
S
F
Q
Q
33.7
110
49.3
85.8
34.8
64.1
28.9
28.7
28.8
29.2
26.1
28.6
2
2
2
2
2
2
4
3
7
44
3
6
4
3
7
55
3
11
4
5
14
144
3
54
33.10%
10.50%
17.00%
47.80%
15.80%
18.40%
DQGTYEDYVEGLR
DQLIVNLLK
DQLLNDIR
DQLVVFHTK
DQVANSAFVER
DQYEQMAEK
K
K
R
K
K
R
V
E
H
D
L
N
58.9
44.9
46.7
48.4
54
42.8
29
22.8
26.3
27.4
28.6
26.8
2
2
2
2
2
2
11
132
13
11
9
11
9
18
2
2
13
196
13
11
9
11
9
23
3
3
29
883
13
20
9
11
12
100
21
21
24.70%
55.20%
14.40%
19.30%
16.40%
15.40%
16.30%
37.20%
54.10%
54.10%
DQYLVWLTQK
DRAEAEAR
DRDLEVDTTLK
DREEALHQFR
DSIFSNLIGQLDYK
DSIISEINR
DSLTLVFVETK
DSQEEEKTEALTSAK
DSYVGDEAQSK
DSYVGDEAQSKR
R
R
R
R
R
K
K
K
K
K
G
E
S
S
G
L
K
R
R
G
40.7
39.8
42.2
38.1
75.6
27.7
44.8
95.7
91.5
66.2
27.8
26.9
28.5
28.6
28.7
27.6
26.4
29.6
27.5
29.6
2
2
2
2
2
2
2
2
2
2
647.3475
459.2269
652.8422
434.2182
806.9168
523.7802
626.3461
833.3958
1,198.52
677.8164
1,292.68
916.4382
1,303.67
1,299.63
1,611.82
1,045.54
1,250.68
1,664.78
1,197.51
1,353.62
1,293.68
917.4442
1,304.67
1,300.64
1,612.82
1,046.55
1,251.68
1,665.78
1,198.52
1,354.62
2
2
2
3
2
2
2
2
1
2
2.20
2.04
4.89
0.63
2.14
4.00
0.52
1.05
0.17
0.75
569
1466
1215
479
423
684
441
663
53
53
578
1473
1225
488
436
692
451
677
63
64
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
7
52
44
43
8
69
55
55
10
255
144
272
9.67%
53.00%
47.80%
47.00%
DTADGTFLVR
DTIEQYK
DTLFQDFK
DTLFQDFKR
R
R
K
K
D
G
R
L
66.3
39.4
41.3
48.8
27.9
26.8
27.2
28.4
2
2
2
2
547.7783
448.7224
507.2514
585.3015
1,093.54
895.4292
1,012.49
1,168.59
1,094.55
896.4367
1,013.49
1,169.60
2
2
2
2
0.37
0.38
0.46
0.39
349
61
525
525
358
67
532
533
TRUE
TRUE
TRUE
TRUE
26
69
6
15
3
3
9
3
57
43
5
138
123
11
30
76
6
15
4
4
13
3
66
50
7
222
194
14
71
172
6
21
130
174
78
7
435
62
87
3511
2027
30
47.90%
42.20%
10.90%
13.60%
14.50%
16.80%
21.90%
9.76%
39.20%
48.90%
35.50%
55.70%
52.30%
34.60%
DTPDGTFLVR
DTQLHLDDALR
DTTASAVAVGLK
DVAVMQLR
DVDAAYMNK
DVDAAYMNK
DVDAAYMNKVELQAK
DVDAAYMSK
DVEALSQR
DVIIQQLQDTLHDLQK
DVLDSVL
DVLLQVEDER
DVLLQVEDERR
DVNAAIATIK
R
K
K
K
K
K
K
K
K
R
K
K
K
K
D
G
Q
S
V
V
A
V
L
R
R
N
T
53.4
62.5
59.2
31.3
52.2
40.4
47.7
33.3
56.9
46
32.4
70.9
58.7
62.2
28.4
28.8
27.6
27.9
27.2
26.8
30.1
26
26.1
25.9
27.4
28.5
28
25.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
560.7891
648.8319
566.8145
474.2539
521.7302
513.7324
855.9271
508.2246
459.2387
954.0183
760.4105
608.3154
686.3657
508.2936
1,119.56
1,295.65
1,131.61
946.4921
1,041.44
1,025.45
1,709.84
1,014.43
916.4618
1,906.02
759.4027
1,214.62
1,370.72
1,014.57
1,120.56
1,296.66
1,132.62
947.4986
1,042.45
1,026.46
1,710.84
1,015.44
917.4693
1,907.02
760.4094
1,215.62
1,371.72
1,015.58
2
2
2
2
2
2
2
2
2
2
1
2
2
2
5.48
0.78
0.29
1.39
0.80
0.27
5.30
0.58
0.37
2.39
1.41
0.63
0.12
0.52
340
1653
520
351
251
251
262
241
1437
398
104
1847
1847
327
349
1663
531
358
259
259
276
249
1444
413
110
1856
1857
336
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
8
3
28
22
13
6
7
5
2
3
2
14
138
19
10
9
10
3
34
26
13
6
8
8
3
3
2
14
222
22
10
9
12
3
49
34
13
6
135
206
20
3
2
15
3511
61
13
9
45.30%
3.17%
39.60%
41.70%
12.60%
8.51%
11.20%
9.33%
19.20%
6.11%
4.52%
20.80%
55.70%
25.80%
13.70%
16.70%
DVQDSVTVSNEVQTAK
DVQNVNFLLK
DYETATLSDIK
DYETATLSEIK
DYEVDATLK
DYFFALAHTVR
DYQELMNTK
DYQELMNVK
DYSPYFK
EAALGAGFSDK
EAATQAQQTLGSTIDK
EAELLEPLMPAIR
EAELTK
EAENFHEDDDVDVKPAK
EAEQQAALAR
EAESSPFVER
K
K
R
K
K
R
R
R
R
R
R
K
K
R
R
K
E
A
A
A
S
D
L
L
T
T
A
A
V
K
L
L
77
44.6
67.5
53.5
30.5
50.1
60.4
60.2
33.8
41.5
72.1
27.4
30.3
60.5
89.9
28.4
29.4
27
28.4
29.1
28.4
28.5
27.7
28.4
25.5
27
29.1
26.2
25.4
30.8
27.6
27.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
860.4251
595.3353
628.3076
635.3156
527.2607
670.3436
579.2631
578.2719
919.4205
533.2648
831.4249
749.4058
690.3682
653.2979
543.7811
575.7742
1,718.83
1,188.65
1,254.60
1,268.62
1,052.51
1,338.67
1,156.51
1,154.53
918.4127
1,064.51
1,660.83
1,496.80
689.3604
1,956.87
1,085.55
1,149.53
1,719.84
1,189.66
1,255.61
1,269.62
1,053.51
1,339.68
1,157.52
1,155.54
919.4203
1,065.52
1,661.83
1,497.80
690.3675
1,957.88
1,086.55
1,150.54
2
2
2
2
2
2
2
2
1
2
2
2
1
3
2
2
1.30
3.83
1.10
1.47
2.93
0.34
2.88
0.24
0.31
0.04
4.36
3.29
1.03
0.02
0.03
2.26
212
641
440
421
1138
51
463
483
140
119
35
129
851
465
72
548
227
650
450
431
1146
61
471
491
146
129
50
141
856
481
81
557
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
3
14
3
14
7
15
24.50%
20.80%
EAFQLFDR
EAGELKPEEEITVGPVQK
K
K
T
L
47.6
34.2
29.2
27.8
2
2
513.257
977.0167
1,024.50
1,952.02
1,025.51
1,953.02
2
2
0.51
3.71
14
496
21
513
TRUE
TRUE
15
24
17
28
28
44
18.40%
34.60%
EAGFSYSHTGLSNR
EAILAIHK
R
R
L
E
83.9
27.4
28.7
20.5
2
2
763.3558
447.7748
1,524.70
893.534
1,525.70
894.5415
2
2
0.34
0.45
503
585
516
592
TRUE
TRUE
5
8
26
26
43
2
31
5
10
32
32
50
2
40
7
18
60
60
62
2
73
6.36%
34.70%
31.90%
31.90%
48.90%
2.74%
17.20%
EALELLDFNYPDQYVR
EALEYKDREDYVPYTGEK
EALNSLSQLSYSTSSSK
EAQAELEDYR
EAQAELEDYRK
EASADLSPYVR
EASDLLEQNR
R
K
K
R
R
K
K
E
K
R
K
R
K
L
78
32.1
118
54.5
49.8
40.2
81
30.3
31.2
29.8
28.1
28.7
28.7
28.2
2
2
2
2
2
2
2
992.9877
735.6847
901.4461
612.2813
676.3303
604.3034
587.7896
1,983.96
2,204.03
1,800.88
1,222.55
1,350.65
1,206.59
1,173.56
1,984.97
2,205.04
1,801.88
1,223.55
1,351.65
1,207.60
1,174.57
2
3
2
2
2
2
2
1.00
1.40
1.38
0.23
2.47
2.56
0.66
605
76
865
624
624
157
657
620
93
881
633
634
167
666
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M5:Oxidation(+15.99)
M11:Oxidation(+15.99)
M6:Oxidation(+15.99)
M5:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
M9:Oxidation(+15.99)
5
42
5
59
8
381
25.80%
43.80%
EASDPQPEDVDGGLK
EASELLR
K
R
S
E
89.6
46.7
29.1
26.7
2
2
778.8593
817.4437
1,555.70
816.4358
1,556.71
817.442
2
1
1.59
2.06
104
823
118
829
15
8
40
17
8
51
28
11
83
18.40%
18.10%
21.50%
EATLVTIK
EAYPGDVFYLHSR
EDENILSGDR
R
R
K
H
L
V
45.4
32.6
62.3
25.2
29.7
28
2
2
2
437.7666
518.5864
574.2665
873.5176
1,552.74
1,146.52
874.5251
1,553.74
1,147.52
2
3
2
0.39
3.09
1.74
39
335
251
46
347
260
TRUE
TRUE
TRUE
11
35
14
3
4
3
13
44
11
43
14
4
7
3
13
53
12
112
15
12
21
5
16
78
19.00%
30.80%
20.80%
64.80%
53.20%
12.90%
21.70%
37.80%
EDENTMYSGQAVQSPPSGHPDVQVR
EDGIAAEIPLASHIPEER
EDIQSVMTEVR
EDKYEEEIK
EDKYEEEIKLLEEK
EDLAR
EDQTEYLEER
EDSTTFASR
R
R
K
K
K
K
K
K
L
R
R
L
L
L
R
E
65.9
68.4
33.4
44
66.5
31.2
59.4
43.2
31.2
29.2
28.4
28.1
28.8
26.8
29
26.7
2
2
2
2
2
2
2
2
915.4152
973.9959
661.8192
1,182.55
897.9578
603.3109
656.2918
507.2322
2,743.22
1,945.98
1,321.62
1,181.54
1,793.90
602.3031
1,310.57
1,012.45
2,744.22
1,946.98
1,322.63
1,182.55
1,794.90
603.3103
1,311.57
1,013.45
3
2
2
1
2
1
2
2
2.82
0.65
3.17
1.41
3.42
0.97
3.94
2.39
329
466
470
218
218
443
187
457
353
483
480
226
231
447
196
465
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
24
32
28
37
88
102
47.20%
65.50%
EDSVEAVGAQLK
EEAESTLQSFR
K
R
V
Q
76.4
48.7
28.3
29
2
2
623.3203
648.8096
1,244.63
1,295.60
1,245.63
1,296.61
2
2
0.03
3.32
430
197
441
207
TRUE
TRUE
15
90
119
11
2
27
118
194
14
2
112
358
3095
39
2
39.10%
45.50%
51.60%
13.30%
11.80%
EEEELISLK
EEELQAALAR
EEILAQAK
EEINELNR
EENIANIVTYPDDGLIDLK
K
K
R
R
K
D
V
E
I
Y
34.9
86.7
62.4
36.5
76.7
28.2
27.9
26.5
27.2
28.8
2
2
2
2
2
545.2882
565.298
901.5001
508.7548
1,066.54
1,088.56
1,128.58
900.4922
1,015.49
2,131.07
1,089.57
1,129.59
901.4996
1,016.50
2,132.08
2
2
1
2
2
0.48
2.52
0.52
0.52
1.22
118
1082
1663
318
195
126
1091
1670
325
213
TRUE
TRUE
TRUE
TRUE
TRUE
1,226.05
1,183.10
759.3342
2,450.08
2,364.19
1,516.65
2,451.08
2,365.19
1,517.66
2
2
2
1.16
3.47
0.14
265
265
371
284
284
384
TRUE
TRUE
TRUE
M9:Oxidation(+15.99),M11:
Oxidation(+15.99)
973.8928
M9:Oxidation(+15.99),M11:
Oxidation(+15.99)
701.6319
872.4392
598.7979
33
5
77
59
5
85
252
8
149
65.10%
69.00%
47.90%
EENLSMHQMLDQTLLELNNM
EENVEIHQTLDQTLLELNNL
EEQAEPDGTEVADK
K
K
R
T
63.8
78.5
68.5
31.4
29.3
28.8
2
2
2
M6:Oxidation(+15.99)
M7:Oxidation(+15.99)
M6:Oxidation(+15.99),M9:
Oxidation(+15.99),M20:
Oxidation(+15.99)
Irs1
Insulinreceptorsubstrate1
IPI00199662
131160
31
42
126
34.10%
EETGSEEYMNMDLGPGR
R
R
86.2
28.5
2
1,945.77
1,946.77
2
1.52
932
948
TRUE
Irs1
Myh9
Kbtbd10
IPI00199662
IPI00209113
IPI00190417
131160
226326
68198
30
119
8
42
194
11
108
3095
19
29.50%
51.60%
18.20%
EETGSEEYMNMDLGPGRR
EEVGEEAIVELVENGK
EEVVFEAVMK
R
K
K
A
K
W
43
100
32.9
29.9
29.3
29.2
2
2
2
2,101.87
1,742.86
1,195.58
2,102.88
1,743.87
1,196.59
3
2
2
1.93
3.03
0.64
932
48
193
949
63
202
TRUE
TRUE
TRUE
Atp2a2
Cald1
Insulinreceptorsubstrate1
Myosin9
KelchrepeatandBTBdomaincontainingprotein10
IsoformSERCA2BofSarcoplasmic/endoplasmicreticulum
calciumATPase2
Caldesmon
5
13
5
16
7
23
6.70%
21.80%
EFDELSPSAQR
EFDPTITDGSLSVPSR
R
K
D
R
36.7
76.7
28.5
29.3
2
2
639.8041
860.9243
1,277.59
1,719.83
1,278.60
1,720.84
2
2
2.89
0.73
658
114
668
129
TRUE
TRUE
Syncrip
Pabpc1
Capza2
70kDaprotein
Polyadenylatebindingprotein1
Factincappingproteinsubunitalpha2
3
6
4
3
6
5
3
9
8
6.58%
13.20%
33.20%
EFNEDGALAVLQQFK
EFSPFGTITSAK
EGAAHAFAQYNLDQFTPVK
K
K
R
D
V
I
63.1
47
56.9
29.2
28.4
29.7
2
2
2
854.9345
642.8287
1,054.03
1,707.85
1,283.64
2,106.04
1,708.85
1,284.65
2,107.03
2
2
2
3.81
1.55
8.65
67
313
48
81
324
66
TRUE
TRUE
TRUE
Capza1
Mprip
Eef2
Hsp90ab1
Jup
Mprip
Cand1
Col1a1
Eef1a1
Hspa8
Immt
Nexn
33kDaprotein
258kDaprotein
Elongationfactor2
HeatshockproteinHSP90beta
Junctionplakoglobin
258kDaprotein
CullinassociatedNEDD8dissociatedprotein1
collagen,type1,alpha1
Elongationfactor1alpha1
Heatshockcognate71kDaprotein
82kDaprotein
Isoform1ofNexilin
8
29
10
25
6
37
12
13
8
16
2
17
10
33
10
26
6
49
12
13
9
19
2
23
12
58
17
38
9
105
12
13
15
59
2
47
45.30%
15.80%
14.60%
37.00%
8.59%
19.50%
12.40%
14.40%
20.80%
33.30%
3.51%
26.70%
EGAAHAFAQYNMDQFTPVK
EGEFTLSAMTSGIR
EGIPALDNFLDKL
EGLELPEDEEEKKK
EGLLAIFK
EGLTVQER
EGPAVVGQFIQDVK
EGSPGAEGSPGR
EHALLAYTLGVK
EIAEAYLGK
EIAGATPYITAAEEK
EIDAALQK
R
K
K
K
R
K
K
R
R
K
R
K
I
R
M
S
L
N
D
Q
T
L
K
34
68.8
57.5
40
46.1
32
35
64.5
60.7
45.8
42.5
46.4
30.9
29.5
27.8
29.7
21.8
26.8
26.9
27.4
26.1
25.5
29.1
26.5
2
2
2
2
2
2
2
2
2
2
2
2
714.3326
757.8627
722.8897
836.9205
445.7723
466.2463
743.9013
550.7551
657.876
497.2667
782.3997
887.4844
2,139.97
1,513.71
1,443.76
1,671.83
889.5289
930.4769
1,485.79
1,099.49
1,313.74
992.5178
1,562.78
886.4766
2,140.98
1,514.72
1,444.77
1,672.83
890.5354
931.4849
1,486.79
1,100.50
1,314.74
993.5258
1,563.79
887.484
3
2
2
2
2
2
2
2
2
2
2
1
2.81
0.99
1.72
2.94
1.48
0.29
2.74
4.47
1.51
0.21
0.49
0.52
48
426
846
539
217
2255
813
1004
135
129
304
526
66
439
858
552
224
2262
826
1015
146
137
318
533
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Agap3
9
13
27
18.80%
EIDLLR
K
T
37.2
27.3
2
4
11
3
2
2
4
11
5
26
132
16
38
28
4
2
19
6
24
40
70
105
5
21
86
113
37
3
3
2
17
5
13
3
3
3
5
12
6
30
196
17
51
40
4
2
20
6
25
44
82
175
5
27
104
179
49
3
3
2
18
5
47
7
15
8
8
13
11
44
883
27
155
261
7
2
38
15
143
116
145
2139
6
59
217
1862
105
3
3
2
25
16.20%
34.60%
4.47%
57.80%
52.80%
12.60%
30.70%
5.91%
32.80%
55.20%
10.50%
77.50%
62.20%
6.93%
2.97%
17.70%
10.60%
19.00%
29.60%
45.50%
47.80%
10.20%
39.60%
50.30%
50.90%
19.50%
5.72%
15.80%
2.97%
20.40%
EIFLSQPILLELEAPLK
EIIDLVLDR
EISGLTGQLDNVK
EITALAPSTMK
EITALAPSTMK
EIVLELVAQVLEHK
EIVTNFLAGFEP
EIVVDGQSYLLLIR
EKENIQTLLK
EKHLAAENR
EKLEAEVQR
EKLQEEMLQR
EKLQEEMLQREEAESTLQSFR
ELAEELR
ELAEQTLNNVK
ELASELR
ELAVQIYEEAR
ELDDATEANEGLSR
ELEAELEDER
ELEAELEDERK
ELEDATETADAMNR
ELEDIEPDR
ELEEIVQPIISK
ELEELSER
ELETQISELQEDLESER
ELEVLSEQYSQK
ELISNASDALDK
ELISNSSDALDK
ELLIIGGVAAR
ELLPVLISAMK
R
K
R
K
K
K
K
K
R
R
R
R
R
R
R
R
R
R
R
R
R
R
K
R
R
R
R
R
R
K
I
I
I
I
I
N
D
S
L
D
E
Q
L
Q
R
K
E
K
Q
E
N
L
L
A
C
I
I
D
I
84.6
74.1
80.6
66
49.4
71.5
50.4
106
48
41.3
36.8
46.3
41
38
50.4
34.3
65.9
116
56.3
39.5
105
33.2
66.3
35.2
108
90.7
74.3
57.6
78.9
36
17.9
26.5
27.9
28.1
27.7
21.1
28
22.9
25.6
27.2
27.5
28
30.3
26.7
28.2
26.7
28.8
29.2
29.1
28.6
29.5
28.1
24.4
27.6
30.1
28.9
28.4
28.2
20.7
24
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Mtdh
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
58223
Serine/threonineproteinphosphatasePP1betacatalytic
subunit
IPI00203390
37170
Tubulinalpha1Bchain
IPI00339167
50134
huntingtininteractingprotein1
IPI00765689
114988
Actin,alphaskeletalmuscle
IPI00189813
42034
Actin,alphaskeletalmuscle
IPI00189813
42034
Calsequestrin2
IPI00231901
49386
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
centaurin,gamma2
IPI00389524
96839
Isoform2ofAnkycorbin
IPI00372146
105981
Myosin9
IPI00209113
226326
Isoform1ofNestin
IPI00194103
208776
Vimentin
IPI00230941
53716
Vimentin
IPI00230941
53716
KelchrepeatandBTBdomaincontainingprotein10 IPI00190417
68198
ATPdependentRNAhelicaseDDX1
IPI00555314
82480
Thrombospondin1
IPI00422076
129653
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
Myosin9
IPI00209113
226326
Leiomodin2
IPI00372026
61700
78kDaglucoseregulatedprotein
IPI00206624
72331
Myosin3
IPI00201578
223846
Myosin9
IPI00209113
226326
258kDaprotein
IPI00392930
257845
Isoform1ofEndoplasmin
IPI00365985
92756
HeatshockproteinHSP90alpha
IPI00210566
84800
ATPdependentRNAhelicaseDDX1
IPI00555314
82480
Vinculin
IPI00365286
116599
IPI00209277,IPI00515783,IPI00515808,I
Isoform1ofProteinLYRIC
PI00515819
63953
2
2
2
3.96%
ELLSVGLGFLR
R
T
58.1
23.1
Pbxip1
Myh10
Scin
PreBcellleukemiatranscriptionfactorinteractingprotein1 IPI00201858
234kDaprotein
IPI00391300
Scinderin
IPI00365568,IPI00391226
80257
233603
80184
2
49
6
2
53
6
2
157
8
4.16%
33.40%
11.30%
ELPLSPAYFGEDGIFR
ELQAQIAELQEDFESEK
ELQGYESTDFVGYFK
K
R
R
H
A
G
61.8
89.9
74.8
29.4
30.3
30.1
8
17
69
8
18
76
14
25
172
22.00%
20.40%
42.20%
ELQSEMEVMAPDPHLPVGMIQK
ELTPQVISAAR
ELTYQSEEDRK
K
R
K
D
I
N
38.1
54.2
53.1
30.9
25.1
28.7
2
2
2
17
26
111
43.90%
ELWQSIHNLEAEK
K
F
44.3
28.8
2
17
42
4
26
53
4
111
149
7
43.90%
45.40%
8.75%
ELWQSIHNLEAEKFDLQEK
ELYERPPHLFAIADAAYK
EMALDNVDPAILDLIIK
K
R
K
F
A
Y
45.8
59.5
82.1
29.1
28.4
26.3
2
2
2
13
122
138
24
44
9
4
50
40
16
16
76
43
8
13
194
222
29
53
12
6
72
54
17
17
92
50
8
13
2067
3511
137
78
37
61
328
117
27
27
323
62
12
12.60%
51.90%
55.70%
51.90%
37.80%
23.80%
35.50%
48.80%
19.90%
10.50%
10.50%
46.50%
48.90%
25.80%
EMATQLAFMR
EMEAELEDER
EMEAELEDERK
EMEENFALEAANYQDTIGR
EMLQDR
ENAELESR
ENAGEDPGLAR
ENLIYTYIGPVLVSVNPYR
ENQELNAHNQELNNR
ENQEPLGYEEAEDQILER
ENQEPLGYEEAEGQILER
ENQSILITGESGAGK
ENSVSITEHLEVITTLR
ENTLNMVVR
K
R
R
R
R
R
K
R
R
K
K
R
K
K
L
K
Q
L
E
I
Q
D
L
L
L
T
T
R
36.1
58.9
62.7
114
31.8
39.6
65.4
107
71
38.3
77.2
95.3
33
57.7
28.6
26.7
28.2
30.5
23.3
26.9
28.7
26.7
30
30.7
30.3
28.1
27.5
28.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Ppp1cb
Tuba1b
Hip1
Acta1
Acta1
Casq2
Atp5a1
Centg2
Rai14
Myh9
Nes
Vim
Vim
Kbtbd10
Ddx1
Thbs1
Ddx3x
Myh10
Myh10
Myh10
Myh9
Lmod2
Hspa5
Myh3
Myh9
Mprip
Tra1
Hsp90aa1
Ddx1
Vcl
IPI00190020,IPI00231369
115376
IPI00208118
60567
IPI00557424,IPI00764064,IPI00776515,I
PI00782066
69603
IPI00189074
70683
IPI00370681
32949
IPI00777201,IPI00778882,IPI00780661,I
PI00782724,IPI00869675
33027
IPI00392930
257845
IPI00203214
95268
IPI00471584
83266
IPI00421429
81784
IPI00392930
257845
IPI00205466
136349
IPI00844828
137936
IPI00195372,IPI00551729
50096
IPI00208205
70855
IPI00364895,IPI00566985
82231
IPI00209938
78377
Lmod3
Vcl
Myh3
similartoleiomodin3
Vinculin
Myosin3
Tnnt2
Isoform2ofTroponinT,cardiacmuscle
Tnnt2
Myo1d
Kbtbd10
Isoform2ofTroponinT,cardiacmuscle
MyosinId
KelchrepeatandBTBdomaincontainingprotein10
IPI00568699
57499
IPI00365286
116599
IPI00201578
223846
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00207989
116081
IPI00190417
68198
Col1a2
Myh9
Myh9
Vim
Lmo7
Krt33a
DCD
Myo1c
Mprip
Nes
Nes
Myh3
Rai14
Htra1
Collagenalpha2(I)chain
Myosin9
Myosin9
Vimentin
LMO7b
TypeIhairkeratinKA27
Dermcidin
MyosinIc
258kDaprotein
Isoform1ofNestin
Isoform1ofNestin
Myosin3
Isoform2ofAnkycorbin
HtrAserinepeptidase1,isoformCRA_a
IPI00188921
IPI00209113
IPI00209113
IPI00230941
IPI00421345
IPI00551773
IPI00421832
IPI00393867
IPI00392930
IPI00194103
IPI00194103
IPI00201578
IPI00372146
IPI00199325
Gsn
Isoform2ofGelsolin
IPI00923716
Agap3
Gsn
Kab
Myh9
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
Isoform2ofGelsolin
IPI00923716
174kDaprotein
IPI00776774
Myosin9
IPI00209113
129547
226326
226326
53716
156634
45954
11266
119797
257845
208776
208776
223846
105981
51312
M9:Oxidation(+15.99)
M12:Oxidation(+15.99)
M9:Oxidation(+15.99)
758.4414
757.4336
758.4414
1
0.05
80
85
TRUE
977.0753
543.3151
687.3684
589.311
581.3145
810.4761
668.8466
809.4675
608.3514
534.2849
551.3001
660.3358
866.426
430.2304
629.8367
409.2257
660.8449
760.3482
616.7877
680.8375
791.3386
558.2647
699.4003
1,004.49
1,024.49
726.8657
638.3259
646.3234
556.3469
615.3641
1,952.14
1,084.61
1,372.72
1,176.61
1,160.61
1,618.94
1,335.68
1,616.92
1,214.69
1,066.55
1,100.58
1,318.66
2,596.25
858.4451
1,257.66
816.4358
1,319.67
1,518.68
1,231.56
1,359.66
1,580.66
1,114.51
1,396.79
1,003.48
2,046.97
1,451.72
1,274.64
1,290.63
1,110.68
1,228.71
1,953.13
1,085.62
1,373.73
1,177.61
1,161.62
1,619.94
1,336.68
1,617.92
1,215.70
1,067.56
1,101.59
1,319.66
2,597.25
859.4526
1,258.66
817.442
1,320.68
1,519.69
1,232.56
1,360.66
1,581.67
1,115.52
1,397.79
1,004.49
2,047.97
1,452.72
1,275.64
1,291.64
1,111.68
1,229.72
2
2
2
2
2
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
1
2
2
2
2
2
2
5.71
1.27
0.92
0.24
1.82
4.39
4.78
3.42
0.03
1.98
1.70
0.49
4.01
0.33
1.00
2.06
1.51
0.51
2.31
5.41
0.59
0.62
2.47
2.52
3.83
0.87
0.41
0.69
1.57
1.92
43
113
383
318
318
88
542
186
803
859
73
187
187
6
297
307
277
1943
1637
1637
1900
36
622
1143
1108
2055
103
47
320
200
59
121
395
328
328
101
553
199
812
867
81
196
207
12
307
313
287
1956
1646
1647
1913
44
633
1150
1124
2066
114
58
330
210
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
2
602.3604
1,202.71
1,203.71
2
2.26
23
33
TRUE
2
2
2
905.9572
1,003.98
891.9188
1,809.90
2,005.95
1,781.82
1,810.90
2,006.96
1,782.82
2
2
2
2.65
2.63
3.99
626
1152
98
641
1168
112
TRUE
TRUE
TRUE
843.071
592.8345
699.3314
2,526.19
1,183.65
1,396.65
2,527.19
1,184.66
1,397.65
3
2
2
3.44
2.34
0.11
34
670
1850
55
680
1860
TRUE
TRUE
TRUE
798.9077
1,595.80
1,596.80
2
3.39
236
248
TRUE
786.3993
702.0344
950.0143
2,356.17
2,103.08
1,898.01
2,357.18
2,104.09
1,899.02
3
3
2
1.93
0.42
2.98
236
70
73
254
87
89
TRUE
TRUE
TRUE
615.2888
633.7639
697.8096
1,109.00
404.1881
474.226
564.7683
1,105.60
911.9262
721.3359
1,052.50
752.3853
647.6834
546.2803
1,228.56
1,265.51
1,393.60
2,215.98
806.3605
946.4364
1,127.52
2,209.18
1,821.84
2,160.98
2,102.99
1,502.76
1,940.03
1,090.55
1,229.57
1,266.52
1,394.61
2,216.98
807.3672
947.4434
1,128.53
2,210.19
1,822.84
2,161.99
2,103.98
1,503.77
1,941.03
1,091.55
2
2
2
2
2
2
2
2
2
3
2
2
3
2
3.21
3.02
0.29
3.71
1.33
0.88
0.14
1.40
0.82
1.43
4.49
1.84
2.60
0.93
1255
1594
1594
346
397
80
43
54
2090
788
700
171
694
455
1264
1603
1604
364
402
87
53
72
2104
805
717
185
710
463
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2,063.07
2,064.07
2
5.16
480
497
TRUE
1,491.71
997.5369
1,209.59
1,304.66
1,492.71
998.5424
1,210.60
1,305.67
2
2
2
2
0.92
2.24
0.64
0.22
520
14
237
408
533
21
246
419
TRUE
TRUE
TRUE
TRUE
M10:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M12:Oxidation(+15.99)
M10:Oxidation(+15.99)
M6:Oxidation(+15.99),M9:
Oxidation(+15.99),M19:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M9:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
80911
28
41
122
49.80%
EPAHLMSLFGGKPMIIYK
K
G
33.3
28
2
M6:Oxidation(+15.99)
M6:Oxidation(+15.99),M14:
Oxidation(+15.99)
1,032.54
58223
80911
173996
226326
10
28
8
138
13
41
8
222
26
122
12
3511
21.40%
49.80%
5.19%
55.70%
EPANGTNPSAELHR
EPGLQIWR
EPSYFEIPTK
EQADFAIEALAK
R
K
R
K
S
V
E
A
47.3
26
44.5
90.7
29.2
25.1
28.9
28.3
2
2
2
2
746.8618
499.7763
605.8041
653.3386
IPI00197888
IPI00230775
IPI00230775
IPI00197888
IPI00230775
IPI00558912
IPI00765011,IPI00360356,IPI00189819
IPI00765011,IPI00360356,IPI00189819
IPI00391300,IPI00558912
IPI00765011,IPI00189819,IPI00896224
IPI00765011,IPI00189819,IPI00896224
IPI00382153,IPI00393340
IPI00382153,IPI00393340
IPI00421855
IPI00197888,IPI00210945,IPI00230775
IPI00230775
IPI00421812
IPI00210566
IPI00558912
IPI00210566
IPI00389524
IPI00765011,IPI00189819,IPI00896224
IPI00765011,IPI00189819,IPI00896224
IPI00471584
IPI00367479,IPI00558912
Myh14
Myh10
Myh3
Lmo7
Lmo7
Rrbp1
Myh10
Myh10
Myh9
Myh9
Rai14
Tcp1
Myh3
Specc1l
Irs1
Hsp90ab1
Ckap4
Myh11
Myh9
myosin,heavychain14
IPI00367479
229088
234kDaprotein
IPI00391300
233603
Myosin3
IPI00201578
223846
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
similartoRibosomebindingprotein1
IPI00188079
143655
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
Isoform2ofAnkycorbin
IPI00372146
105981
Tcomplexprotein1subunitalpha
IPI00200847
60343
Myosin3
IPI00201578
223846
CytospinA
IPI00372846
124324
Insulinreceptorsubstrate1
IPI00199662
131160
HeatshockproteinHSP90beta
IPI00471584
83266
cytoskeletonassociatedprotein4
IPI00365982
63529
similartoMyosin11
IPI00558912
226689
Myosin9
IPI00209113
226326
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
IPI00554334
81251
Arhgef2
Rhoguaninenucleotideexchangefactor2
IPI00368617
111895
Ppp1r12b
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
111371
Mprip
258kDaprotein
IPI00392930
257845
Mprip
258kDaprotein
IPI00392930
257845
Myh3
Myosin3
IPI00201578
223846
Fn1
Isoform1ofFibronectin
IPI00200757,IPI00231982,IPI00231983 272486
Lrrfip2
Leucinerichrepeatflightlessinteractingprotein2
IPI00373564,IPI00780550
49756
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
Pik3ca
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
Nes
Isoform1ofNestin
IPI00194103
208776
IPI00190240,IPI00198550,IPI00361888,I
PI00391830,IPI00476033,IPI00656453,I
PI00776427,IPI00882520
17934
Rps27a
RibosomalproteinS27a
Rai14
Isoform2ofAnkycorbin
IPI00372146
105981
Clip2
111kDaprotein
IPI00476704
111364
Lmo7
LMO7b
IPI00421345
156634
Cltc
Clathrinheavychain1
IPI00193983
191585
Actn1
Alphaactinin1
IPI00209082,IPI00454431
102946
Rai14
Isoform2ofAnkycorbin
IPI00372146
105981
Mprip
258kDaprotein
IPI00392930
257845
Specc1l
CytospinA
IPI00372846
124324
Specc1l
CytospinA
IPI00372846
124324
Krt33a
TypeIhairkeratinKA27
IPI00551773
45954
Vim
Vimentin
IPI00230941
53716
Dsp
similartodesmoplakinisoformIisoform2
IPI00366081
332383
Actn4
Alphaactinin4
IPI00213463
104900
Atp5a1
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
Krt17
Keratin,typeIcytoskeletal17
IPI00370073
48106
Krt42
Keratin,typeIcytoskeletal42
IPI00421791
50196
Tubb6
Tubulin,beta6
IPI00195673
50041
Tubb5
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Vcp
TransitionalendoplasmicreticulumATPase
IPI00212014,IPI00778228
89519
RGD1563532 86kDaprotein
IPI00568788,IPI00768137
85638
Mvp
Majorvaultprotein
IPI00231381
96806
Ncl
Nucleolin
IPI00231827,IPI00882501
77259
Htra1
HtrAserinepeptidase1,isoformCRA_a
IPI00199325
51312
Gsn
Isoform2ofGelsolin
IPI00923716
80911
15
16
17
17
28
27
3
29
28
45
27
10
34
37
21
12
9
29
9
22
5
13
4
6
15
2
5
3
3
6
15
3
35
31
54
29
11
39
49
23
13
12
39
9
24
6
17
5
6
16
2
5
3
3
7
19
21
51
43
120
29
13
69
105
36
18
37
105
21
38
7
325
21
14
69
2
5
3
4
15
75
Lmo7
Eef1a1
Irs1
Ap2b1
IPI00421345
156634
IPI00195372,IPI00551729
50096
IPI00199662
131160
IPI00231502,IPI00389753,IPI00781916 105677
39
10
33
4
49
12
45
4
116
27
88
4
27
17
13
7
32
21
2
8
38
3
16
27
5
3
2
2
16
50
11
13
33
23
13
7
37
27
2
8
51
3
19
34
8
3
2
2
19
65
13
19
Tnnt2
Gsn
Myh9
Mprip
Myo1d
Hspa8
Hspa5
Eif3c
Copb2
Hspa8
Atp5a1
Hnrpm
Krt17
Akt1
Mprip
Copg
Dsp
Psmd2
Clip2
IPI00554334
81251
IPI00209938
78377
IPI00364904
109514
IPI00190417
68198
IPI00230941
53716
IPI00382153
61809
IPI00421812
61742
IPI00454476,IPI00780672
62207
IPI00230941
53716
IPI00365985
92756
IPI00209082,IPI00454431
102946
IPI00230941
53716
IPI00421857
64814
IPI00454475
57238
IPI00200847
60343
IPI00627068
75469
IPI00208205
70855
IPI00393867
119797
IPI00339167
50134
IPI00339167
50134
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
Isoform2ofGelsolin
IPI00923716
80911
Myosin9
IPI00209113
226326
258kDaprotein
IPI00392930
257845
MyosinId
IPI00207989
116081
Heatshockcognate71kDaprotein
IPI00208205
70855
78kDaglucoseregulatedprotein
IPI00206624
72331
Eukaryotictranslationinitiationfactor3subunitC
IPI00914189
105420
Coatomersubunitbeta'
IPI00231953
102535
Heatshockcognate71kDaprotein
IPI00208205
70855
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
77613
Keratin,typeIcytoskeletal17
IPI00370073
48106
RACalphaserine/threonineproteinkinase
IPI00212844
55719
258kDaprotein
IPI00392930
257845
Coatomersubunitgamma
IPI00780394
98515
similartodesmoplakinisoformIisoform2
IPI00366081
332383
26SproteasomenonATPaseregulatorysubunit2
IPI00370456
100172
111kDaprotein
IPI00476704
111364
17
28
107
32
43
18
19
6
4
18
11
9
22
6
31
9
10
3
30
Mprip
Sfpq
Pkm2
Ncl
Capza2
258kDaprotein
Splicingfactorproline/glutaminerich
IsoformM2ofPyruvatekinaseisozymesM1/M2
Nucleolin
Factincappingproteinsubunitalpha2
40
3
4
2
2
Capza1
Myo1d
IPI00392930
257845
IPI00627068
75469
IPI00339197,IPI00764193
57922
IPI00231827,IPI00882501
77259
IPI00370681
32949
IPI00777201,IPI00778882,IPI00780661,I
PI00782724,IPI00869675
33027
IPI00207989
116081
33kDaprotein
MyosinId
Isoform2ofProcollagenlysine,2oxoglutarate5dioxygenase
2
IPI00208888,IPI00370551
similartodesmoplakinisoformIisoform2
IPI00366081
TypeIIkeratinKb15
IPI00207038
similartoKeratin,typeIIcytoskeletal6G
IPI00768956
Keratin,typeIIcytoskeletal73
IPI00421780
5
52
5
69
6
255
27.20%
53.00%
FITHAPPGEFNEVFNDVR
FIVDGDTPLIENGK
K
K
L
V
48.3
98.3
30.3
28.6
2
2
697.0107
759.397
2,088.01
1,516.78
2,089.01
1,517.79
3
2
1.01
0.59
20
282
37
295
TRUE
TRUE
86940
332383
58080
57419
60370
5
11
2
3
3
6
11
2
3
3
7
39
27
5
7
8.44%
5.14%
13.80%
11.60%
9.76%
FLDLLLTLDYPK
FLDQNLQK
FLEQQNK
FLEQQNQVLETK
FLEQQNQVLQTK
R
K
R
R
R
E
Y
V
W
W
71.6
40
45.5
41.6
92.1
24.5
26.8
26.2
28.9
28.6
2
2
2
2
2
725.9172
503.2723
453.7391
738.8897
738.3959
1,449.82
1,004.53
905.4626
1,475.76
1,474.78
1,450.82
1,005.54
906.4686
1,476.77
1,475.79
2
2
2
2
2
4.57
0.21
2.06
1.02
1.30
314
1064
163
151
151
325
1071
169
162
162
TRUE
TRUE
FALSE
TRUE
FALSE
IPI00209113
IPI00551812
226326
56336
119
3
194
4
3095
5
51.60%
9.83%
FLSNGHVTIPGQQDKDMFQETMEAMR
FLSQPFQVAEVFTGHMGK
R
R
I
L
40.8
35.7
31.8
29.5
2
2
M17:Oxidation(+15.99),M22:
Oxidation(+15.99),M25:
Oxidation(+15.99)
765.3507
M16:Oxidation(+15.99)
680.3423
3,057.37
2,038.00
3,058.37
2,039.01
4
3
2.61
2.53
302
463
327
480
TRUE
TRUE
IPI00769069,IPI00769166
Pik3r2
Nexn
Kif5b
Kbtbd10
Vim
Krt5
Krt76
Kb23
Vim
Tra1
Actn1
Vim
Krt1
Krt77
Tcp1
Sfpq
Hspa8
Myo1c
Tuba1b
Tuba1b
Plod2
Dsp
Kb15
LOC683613
Krt73
Myh9
Atp5b
LMO7b
Elongationfactor1alpha1
Insulinreceptorsubstrate1
Isoform2ofAP2complexsubunitbeta1
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
Isoform1ofNexilin
Kinesin1heavychain
KelchrepeatandBTBdomaincontainingprotein10
Vimentin
Keratin,typeIIcytoskeletal5
TypeIIkeratinKb9
TypeIIkeratinKb23
Vimentin
Isoform1ofEndoplasmin
Alphaactinin1
Vimentin
Keratin,typeIIcytoskeletal1
Keratin,typeIIcytoskeletal1b
Tcomplexprotein1subunitalpha
Splicingfactorproline/glutaminerich
Heatshockcognate71kDaprotein
MyosinIc
Tubulinalpha1Bchain
Tubulinalpha1Bchain
Pik3ca
Myosin9
ATPsynthasesubunitbeta,mitochondrial
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
Cand1
Kab
Stat1
Tubb5
Mprip
Dpysl2
Thbs1
Tra1
Myo1c
Lrrfip2
Pabpc1
Eef2
Mrlc2
Thbs1
CullinassociatedNEDD8dissociatedprotein1
174kDaprotein
Ab2131
Isoform1ofTubulinbeta5chain
258kDaprotein
Dihydropyrimidinaserelatedprotein2
Thrombospondin1
Isoform1ofEndoplasmin
MyosinIc
Leucinerichrepeatflightlessinteractingprotein2
Polyadenylatebindingprotein1
Elongationfactor2
MyosinregulatorylightchainMRLC2
Thrombospondin1
Capza1
Capza2
Stat1
Rpn1
Hadha
Eprs
Thbs1
Myh9
Akt1
Col1a1
LOC682005;G
apdh;LOC685
186
Rai14
Pkm2
Emilin1
Myh9
Myh9
Kpnb1
Agap3
Col1a2
Myo1c
Flii
Irs1
DCD
Pik3r2
Clip2
Clip2
Pkm2
Myh9
Myo1d
Col1a1
Thbs1
Myo1c
Col1a2
Myo1c
Pik3ca
Kb15
Myh9
Col1a2
Col1a1
Lmo7
Pdia6
Mprip
Plod2
Dsp
Copa
Ncl
Pabpc1
Msi2
Msi2
Thbs1
Pik3r2
Col1a1
Krt2
Purb
Purb
Purb
Eef2
Kif5b
3
38
68
44
46
3
55
55
119
122
43
2
76
21
31
15
8
2
132
3
44
78
55
58
3
59
59
194
194
50
2
92
23
42
15
9
2
196
23
150
99
141
181
3
166
166
3095
2067
62
2
323
36
126
29
13
2
883
5.15%
29.70%
43.10%
38.90%
39.90%
2.71%
38.10%
38.10%
51.60%
51.90%
48.90%
3.78%
46.50%
25.00%
34.10%
24.60%
20.20%
8.74%
55.20%
EQADFALEALAK
EQADFAVEALAK
EQDTSAHLER
EQEAQEEELR
EQEAQEEELRK
EQEIAAVQAR
EQEVAELK
EQEVAELKK
EQEVSILK
EQEVSILKK
EQEVTELVQK
EQLAIAEFAR
EQLAIVER
EQLLGVQQHLSNTLK
EQQQQQQQQQQSSLHPPEPK
EQVANSAFVER
ERDFTSLENTVEER
EREQLK
ERNTDQASMPDNTAAQK
K
K
K
K
K
R
R
R
R
R
K
R
K
R
R
K
R
R
K
A
A
M
K
Q
M
K
A
K
T
F
S
R
M
S
V
L
Q
V
90.7
79.4
58.8
62.4
67.6
52.5
39.8
36.9
53.5
31.6
54.6
48.8
39.9
73.1
57.2
61.9
48.9
35.4
49.3
28.3
28.4
28.5
28.7
29
26.3
27.8
28.5
27
25.4
28
28.1
25.6
25.6
30.8
28.4
30
28.9
30
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
26
9
7
35
31
55
8
6
30
9
7
51
40
62
9
6
83
9
8
95
73
146
12
12
47.20%
13.30%
10.60%
18.00%
17.20%
37.80%
4.68%
16.20%
ERPEDLELLPGDLLVVSR
ERPTSAIYPSDSFR
ESAVNLVR
ESEIQYLK
ESHLLNDEDLTQAK
ESIVSQLSR
ESKPLTAQQTTK
ESLSEVEEK
R
R
R
K
R
K
R
R
V
Q
S
Q
P
S
L
Y
73.4
37.2
47.3
45.9
70.2
66.5
32.2
42.1
23.7
30.1
27.8
27
29
28
27.5
27.7
2
2
2
2
2
2
2
2
18.40%
10.50%
ESLYSQLPIDSFTMPSYSR
ESQEVVRPSK
K
K
R
E
51.6
38.7
30.5
28
2
2
21.80%
36.10%
34.30%
37.60%
21.50%
23.30%
39.20%
19.50%
25.00%
15.00%
23.80%
67.20%
3.75%
32.30%
13.70%
29.60%
24.10%
30.40%
37.60%
3.09%
7.64%
4.71%
3.92%
18.10%
32.60%
ESTLHLVLR
ESVFFAEAPFK
ESVLNSSVK
ESVTASWEPSWSEGSK
ESYVETELIFALAK
ETADTDTADQVMASFK
ETEADLSFQSFHSTQTDLAPSPSK
ETGLDSKEDENILSGDR
ETIFELEDEVEQHR
ETIIAHQPTDVESTLLQLQEQNTAIR
ETMQFLNDR
ETNLESLPLVDTHSK
ETQSQLETER
ETTDTDTADQVIASFK
EVAAFAQFGSDLDAATQQLLSR
EVATNSELVQSGK
EVATNTEALQSSR
EVDEQMLAIQNK
EVDEQMLNVQNK
EVDIGIPDATGR
EVEVAASTAAGAPAQR
EVEVVEIIQATVIK
EVFEDAVEIR
EVPVASGSGFIVSEDGLIVTNAHVVTNK
EVQGFESSTFQGYFK
K
K
R
R
R
R
K
R
K
K
K
R
R
R
R
R
R
K
K
R
R
K
K
R
R
L
A
T
S
T
I
S
V
A
E
L
R
C
V
G
S
T
N
N
L
A
Q
L
N
S
42.9
52.2
46.3
53.3
68.1
107
39.1
69.1
31.4
39.9
68
70.2
37.5
97.7
110
86.4
32.7
46.2
92.1
31.8
55.4
52.6
52.6
42.9
83.9
23.8
28.2
26.9
30.2
26.8
29.6
31.4
30.4
30.3
27.2
28
29.1
28.2
29.8
28.9
28.7
28.8
29.4
29.1
27.8
28.7
22.1
28.7
25.3
30.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
32.70%
24.50%
36.00%
5.15%
EVSRSPDQFSDMR
EVSTYIK
EVWQVILKPK
EYATEVDVDFVR
R
K
K
K
I
K
G
K
52
33.8
46.3
43.6
27.7
26.3
20
29.3
2
2
2
2
100
47
13
9
102
711
3
49
155
3
32
107
220
5
2
2
59
289
41
40
50.10%
26.70%
17.30%
11.90%
65.50%
29.00%
9.81%
11.40%
77.50%
5.72%
35.10%
60.90%
9.60%
12.90%
3.78%
3.15%
33.30%
48.90%
34.60%
40.80%
EYDQLYEEYTR
EYEELIK
EYELLSDELNQK
EYFLSEIEEEK
EYQDLLNVK
EYQELMNTK
EYQELMNVK
FAAFIDK
FADLSEAANR
FAFQAEVNR
FAIQDISVEETSAK
FANYIDK
FASFIDK
FASFIDKVR
FATEAAITILR
FATHAAALSVR
FDDAVVQSDMK
FDEVLIR
FDGALNVDLTEFQTNLVPYPR
FDLMYAK
R
R
K
R
R
R
R
R
K
K
R
R
K
K
K
R
R
R
R
K
T
L
S
K
M
L
L
V
N
M
E
V
V
F
I
N
H
H
I
R
70.5
39.6
48.5
53.3
55.3
55.1
44.6
48.6
84.6
59.5
90.4
50.8
45.3
58
74.3
41.8
74.4
42
124
50.6
28.9
26.4
29.1
29
27.6
28.3
29
28
27.3
29.1
27.8
25.7
25.5
25.5
24.5
27
28.1
26.1
29.4
27.3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
26
41
169
43
55
22
20
6
4
24
12
9
33
8
40
9
10
3
33
111
122
1242
100
272
56
36
6
4
59
13
11
468
16
73
10
27
3
42
43.90%
49.80%
49.10%
18.20%
47.00%
37.30%
33.90%
8.89%
5.08%
39.00%
30.70%
16.70%
41.10%
16.00%
17.20%
12.90%
4.07%
4.63%
33.70%
FDLQEK
FDLVPVPPNLYGDFFTGDAYVILK
FDQLLAEEK
FEALDIEK
FEEALQSIFNR
FEELNADLFR
FEELNMDLFR
FEELTNLIR
FELALQLGELK
FELTGIPPAPR
FESAFLSHVVSQHQSLLGNIR
FESPEVAER
FETEQALR
FFANIVWQDVYEK
FFILYEHGLLR
FGAQNEEMLPSILVLLK
FGDSNTVMR
FGGSGSQVDSAR
FGLFAPIHK
K
K
K
K
R
R
K
R
R
K
K
K
K
R
R
K
K
R
K
F
T
T
A
W
G
S
T
I
G
S
A
M
K
Y
R
F
M
V
31.4
60.3
65.1
47.3
78.3
67.1
51.2
46
56.1
49
36.7
38.6
42.1
53.5
50.8
53.8
51.9
74.2
36.6
26.9
27
28
26.9
29.3
28.7
29
26.7
25.1
25.6
27.4
27.6
27.4
29.4
26.1
25.5
27.6
28.3
27.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
51
3
5
2
2
83
3
5
2
2
21.50%
6.01%
13.90%
3.22%
15.00%
FGMLDTNDGPGMEDTALR
FGQGGAGPVGGQGPR
FGVEQDVDMVFASFIR
FGYVDFESAEDLEK
FIIHAPPGEFNEVFNDVR
R
R
K
K
K
M
G
K
A
L
116
69.8
38
64.2
49.9
30.3
29.1
30.1
29.8
29.5
2
2
2
2
2
124233
10
11
17
10.10%
FLVEQMR
K
Q
42.7
28.6
2
12
8
4
15
40
2
19
9
50
4
5
11
3
12
12
8
4
16
54
2
20
9
72
4
5
12
4
12
12
12
4
69
117
2
38
9
328
6
6
16
5
13
12.40%
5.19%
4.55%
37.60%
19.90%
6.29%
17.70%
16.70%
48.80%
9.61%
11.30%
15.50%
22.70%
11.70%
FMATNDLMTELQK
FNPDGEEEDVTVHE
FNQAQEGNIQNTVMLDK
FPGQLNADLR
FQANIFNK
FQLTDSQIYEVLSVIR
FQMIPLDPK
FQSSHHSTDITSLDQYVER
FRENLIYTYIGPVLVSVNPYR
FSAEDEALSNIAR
FSPAGPILSIR
FSVSPVVR
FTDEEVDELYR
FTGSQPFGR
R
R
R
R
K
R
R
R
R
R
K
K
R
R
D
Q
K
S
D
G
M
D
E
V
V
E
G
56
65.1
87.7
62
48.9
97.9
46.2
55.8
55.7
79.9
51
45.5
47.3
44.4
29.1
28.7
30.4
28.5
28.4
26.6
27.7
30.8
24.1
28.6
26
25.4
28.8
28.8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
33kDaprotein
Factincappingproteinsubunitalpha2
Ab2131
Ribophorin1
Trifunctionalenzymesubunitalpha,mitochondrial
170kDaprotein
Thrombospondin1
Myosin9
RACalphaserine/threonineproteinkinase
collagen,type1,alpha1
IPI00205466
136349
IPI00776774
173996
IPI00213245,IPI00382229,IPI00655247 134593
IPI00197579
49653
IPI00392930
257845
IPI00870112
62260
IPI00422076
129653
IPI00365985
92756
IPI00393867
119797
IPI00373564,IPI00780550
49756
IPI00189074
70683
IPI00203214
95268
IPI00421625,IPI00564409,IPI00914162 19821
IPI00422076
129653
IPI00777201,IPI00778882,IPI00780661,I
PI00782724,IPI00869675
33027
IPI00370681
32949
IPI00213245,IPI00382229,IPI00655247 134593
IPI00204365
68384
IPI00212622
82649
IPI00421357,IPI00476855
170072
IPI00422076
129653
IPI00209113
226326
IPI00212844
55719
IPI00844828
137936
8
4
4
4
9
9
12
138
6
13
10
5
4
5
9
9
12
222
8
13
12
8
4
5
9
9
13
3511
16
13
45.30%
33.20%
4.55%
11.20%
16.40%
7.99%
11.70%
55.70%
16.00%
14.40%
FTITPPTAQVVGVLK
FTVTPSTTQVVGILK
FTYEQDPITK
FVDHVFDEQVIDSLTVK
FVDLYGAQK
FVELPGAEMGK
FVFGTTPEDILR
FVSELWK
FYGAEIVSALDYLHSEK
GAAGPPGATGFPGAAGR
K
K
K
R
R
K
R
K
R
R
I
I
N
I
V
V
N
D
N
V
53.8
71.3
35.4
44.4
33.9
29.9
59.1
55.5
82
81.9
20
21.5
28.6
28.6
26.8
27.9
27.6
27.5
29.7
28
2
2
2
2
2
2
2
2
2
2
Glyceraldehyde3phosphatedehydrogenase
Isoform2ofAnkycorbin
IsoformM2ofPyruvatekinaseisozymesM1/M2
elastinmicrofibrilinterfacer1
Myosin9
Myosin9
Importinsubunitbeta1
IPI00555252,IPI00567177
IPI00372146
IPI00339197,IPI00764193
IPI00199867
IPI00209113
IPI00209113
IPI00204261
35810
105981
57922
107542
226326
226326
97167
3
26
4
11
119
138
8
4
30
4
11
194
222
8
5
44
7
11
3095
3511
9
18.00%
32.80%
11.30%
15.40%
51.60%
55.70%
13.20%
GAAQNIIPASTGAAK
GADLNLVDSLGHNALYYSK
GADYLVTEVENGGSLGSK
GAIGPPGPQGEQGVEGAPAAPVPR
GALALEEK
GALALEEKR
GALQYLVPILTQTLTK
R
K
K
R
K
K
K
A
L
K
V
R
R
Q
90.3
89.4
63.1
30.8
59.8
68.6
44.9
26.3
29.1
30.1
28.1
26.8
26.1
16.8
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
Collagenalpha2(I)chain
IPI00188921
MyosinIc
IPI00393867
FlightlessIhomolog
IPI00211698
Insulinreceptorsubstrate1
IPI00199662
Dermcidin
IPI00421832
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
111kDaprotein
IPI00476704
111kDaprotein
IPI00476704
IsoformM2ofPyruvatekinaseisozymesM1/M2
IPI00339197,IPI00764193
Myosin9
IPI00209113
MyosinId
IPI00207989
collagen,type1,alpha1
IPI00844828
Thrombospondin1
IPI00422076
MyosinIc
IPI00393867
Collagenalpha2(I)chain
IPI00188921
MyosinIc
IPI00393867
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
TypeIIkeratinKb15
IPI00207038
Myosin9
IPI00209113
Collagenalpha2(I)chain
IPI00188921
collagen,type1,alpha1
IPI00844828
LMO7b
IPI00421345
proteindisulfideisomeraseassociated6
IPI00365929
258kDaprotein
IPI00392930
Isoform2ofProcollagenlysine,2oxoglutarate5dioxygenase
2
IPI00208888,IPI00370551
similartodesmoplakinisoformIisoform2
IPI00366081
Copaprotein
IPI00372458
Nucleolin
IPI00231827,IPI00882501
Polyadenylatebindingprotein1
IPI00189074
similartoMusashihomolog2
IPI00372674,IPI00765904
similartoMusashihomolog2
IPI00372674,IPI00765904
Thrombospondin1
IPI00422076
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
collagen,type1,alpha1
IPI00844828
Keratin,typeIIcytoskeletal2epidermal
IPI00551558,IPI00559533
TranscriptionalactivatorproteinPurbeta
IPI00189358
TranscriptionalactivatorproteinPurbeta
IPI00189358
TranscriptionalactivatorproteinPurbeta
IPI00189358
Elongationfactor2
IPI00203214
Kinesin1heavychain
IPI00364904
58223
129547
119797
144843
131160
11266
9
13
47
9
29
4
13
13
62
9
39
4
27
13
175
17
105
21
18.80%
12.60%
46.60%
8.50%
31.90%
35.50%
GANGLALER
GAPGAIGAPGPAGASGDRGEAGAAGPSGPAGPR
GAPVGGHILSYLLEK
GAQATLSNTTK
GASTLTAPNGHYILSR
GAVHDVKDVLDSVL
R
R
K
R
K
K
S
G
S
A
G
67.9
32.6
112
58.6
77.8
71.5
81251
111364
111364
57922
226326
116081
137936
129653
119797
129547
119797
24
19
30
3
119
42
17
19
43
13
50
28
20
33
3
194
50
17
20
59
13
65
88
31
42
3
3095
166
17
38
215
13
289
47.20%
21.40%
33.70%
7.88%
51.60%
46.10%
20.90%
17.70%
45.00%
12.60%
48.90%
GDFPGTYVEFLGPVALAR
GDKDLHLGDR
GDLELTTVAEK
GDLGIEIPAEK
GDMPFVVTR
GDPIGGHINNYLLEK
GDRGETGPAGPPGAPGAPGAPGPVGPAGK
GDVNDNFQGVLQNVR
GDVVLQSDHVIETLTK
GEAGAAGPSGPAGPR
GEELLSPLNLEQAAYAR
R
R
K
R
R
K
K
K
K
R
K
P
V
S
V
R
S
N
F
T
G
D
124233
58080
226326
129547
137936
156634
48743
257845
11
3
111
2
17
44
2
40
12
6
172
2
17
55
2
51
26
107
2414
2
17
141
2
83
12.00%
16.90%
50.00%
2.19%
20.90%
38.90%
6.29%
21.50%
GEIYDAAIDLFTR
GELALK
GELANEVK
GEPGPAGSVGPVGAVGPR
GEPGPSGLPGPPGER
GESLDNLDSQRPGSWR
GESPVDYDGGR
GFAAMEETHQK
K
R
R
R
R
R
K
R
86940
332383
138346
77259
70683
34694
34694
129653
5
9
15
7
6
2
2
12
6
9
15
7
6
2
2
12
7
20
21
10
9
2
2
13
8.44%
4.00%
13.60%
12.90%
13.20%
9.32%
9.32%
11.70%
GFALLNFVVK
GFFDPNTEENLTYLQLK
GFFEGSIASK
GFGFVDFNSEEDAK
GFGFVSFER
GFGFVTFADPASVDK
GFGFVTFENEDVVEK
GFIFLASLR
81251
137936
69273
33515
33515
33515
95268
109514
26
17
5
4
4
2
10
2
30
17
9
4
4
2
10
2
83
17
199
4
4
4
13
2
47.20%
20.90%
8.16%
22.70%
22.70%
10.10%
12.80%
2.80%
1,304.66
1,290.65
1,184.55
1,259.56
1,387.66
1,113.58
944.4824
1,072.58
944.5176
1,072.61
1,201.62
1,146.61
956.5292
1,706.94
2,400.14
1,248.61
1,723.81
801.4349
1,891.84
1,305.67
1,291.65
1,185.55
1,260.57
1,388.67
1,114.59
945.4893
1,073.58
945.5258
1,073.62
1,202.63
1,147.61
957.5371
1,707.94
2,401.15
1,249.62
1,724.81
802.4423
1,892.84
2
2
2
2
2
2
2
2
2
2
2
2
2
2
3
2
2
2
2
0.22
0.69
3.02
0.32
0.12
3.43
0.94
0.49
0.41
0.65
2.06
2.59
0.02
2.74
0.37
1.11
3.99
0.43
3.44
439
452
1773
1045
1045
676
1210
1210
1166
1166
815
434
1670
508
871
492
206
967
357
450
463
1782
1054
1055
685
1217
1218
1173
1174
824
443
1677
522
890
502
219
972
373
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,025.56
813.4019
444.2515
505.264
806.8958
509.7806
666.3648
525.2543
2,049.11
1,624.79
886.4874
1,008.51
1,611.78
1,017.55
1,330.71
1,048.49
2,050.12
1,625.79
887.495
1,009.52
1,612.78
1,018.55
1,331.72
1,049.50
2
2
2
2
2
2
2
2
1.27
2.20
0.32
0.45
1.08
0.02
3.33
0.50
18
118
514
2146
30
1296
984
151
35
131
521
2153
43
1304
995
159
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,119.03
579.8112
2,236.04
1,157.61
2,237.04
1,158.61
2
2
0.73
2.35
291
634
309
643
TRUE
TRUE
534.3153
636.3195
481.762
883.8994
806.9307
873.3818
875.0771
939.4417
591.9478
983.5183
585.267
841.9348
610.7927
871.4133
1,169.60
681.3497
703.3507
717.3527
731.8472
621.8201
764.3944
785.4627
603.8059
947.1735
877.4092
1,066.61
1,270.62
961.5084
1,765.78
1,611.85
1,744.75
2,622.21
1,876.87
1,772.82
2,947.53
1,168.52
1,681.85
1,219.57
1,740.81
2,337.18
1,360.68
1,404.69
1,432.69
1,461.68
1,241.62
1,526.77
1,568.91
1,205.60
2,838.50
1,752.80
1,067.62
1,271.63
962.5158
1,766.79
1,612.85
1,745.75
2,623.22
1,877.87
1,773.83
2,948.53
1,169.53
1,682.86
1,220.58
1,741.81
2,338.17
1,361.69
1,405.69
1,433.69
1,462.68
1,242.63
1,527.78
1,569.91
1,206.60
2,839.48
1,753.81
2
2
2
2
2
2
3
2
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
3
2
1.18
0.03
0.42
2.09
3.73
1.00
0.31
1.39
1.01
2.21
0.03
0.97
1.33
3.18
7.38
0.30
0.90
1.99
1.28
0.66
2.82
4.53
2.66
7.37
1.97
64
274
190
986
1166
819
348
244
689
230
58
425
1930
838
442
285
295
325
325
366
302
166
416
198
97
72
284
198
1001
1179
834
371
260
702
255
66
439
1939
853
463
297
307
336
336
377
317
179
425
225
111
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
825.3358
420.2295
620.3801
721.8466
1,648.66
838.4434
1,238.74
1,441.68
1,649.66
839.4515
1,239.75
1,442.68
2
2
2
2
0.39
0.32
4.46
3.50
723
173
157
360
735
179
166
371
TRUE
TRUE
TRUE
TRUE
754.8317
923.4719
740.8641
708.3344
561.2968
586.2703
585.2794
811.4366
547.2678
541.2753
769.3931
435.7219
827.4307
541.804
603.3491
572.3187
635.7863
446.251
1,205.11
452.2178
1,507.65
922.464
1,479.71
1,414.65
1,120.58
1,170.52
1,168.54
810.4288
1,092.52
1,080.54
1,536.77
869.4282
826.4229
1,081.59
1,204.68
1,142.62
1,269.56
890.4863
2,408.20
902.42
1,508.65
923.4727
1,480.72
1,415.66
1,121.58
1,171.53
1,169.55
811.4355
1,093.53
1,081.54
1,537.78
870.4361
827.4304
1,082.60
1,205.69
1,143.63
1,270.56
891.4941
2,409.21
903.4287
2
1
2
2
2
2
2
1
2
2
2
2
1
2
2
2
2
2
2
2
0.67
0.95
2.25
1.92
1.23
1.91
0.18
1.40
0.08
0.19
2.09
0.10
0.41
0.15
0.64
1.85
1.76
0.03
0.74
0.97
453
410
515
60
382
448
445
115
295
76
134
114
190
178
516
358
78
618
244
395
463
416
526
70
390
456
453
121
304
84
147
120
196
186
526
368
88
624
264
401
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
779.3947
900.8088
546.7822
482.7535
677.3444
627.3126
665.3134
567.8134
630.8646
599.337
790.4198
532.2573
497.2546
829.9185
704.395
959.5269
521.7358
584.2742
515.2991
778.3869
2,699.40
1,091.55
963.4913
1,352.67
1,252.61
1,328.61
1,133.61
1,259.71
1,196.66
2,368.24
1,062.50
992.4935
1,657.82
1,406.77
1,917.04
1,041.46
1,166.53
1,028.58
779.3941
2,700.40
1,092.56
964.4994
1,353.68
1,253.62
1,329.62
1,134.62
1,260.72
1,197.66
2,369.24
1,063.51
993.5006
1,658.82
1,407.78
1,918.04
1,042.46
1,167.54
1,029.59
1
3
2
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
0.75
5.39
1.31
0.28
0.57
0.61
3.06
2.51
0.61
2.38
3.16
0.61
0.71
4.51
2.28
5.05
1.03
1.08
1.70
249
25
1447
312
772
302
327
57
645
459
507
698
173
407
73
507
924
358
277
254
48
1455
319
782
311
336
65
655
469
527
706
180
419
83
523
932
369
285
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M3:Oxidation(+15.99),M12:
Oxidation(+15.99)
986.429
671.3367
938.4564
824.8743
701.0246
1,970.84
1,340.66
1,874.90
1,647.73
2,100.05
1,971.84
1,341.67
1,875.90
1,648.74
2,101.05
2
2
2
2
3
3.61
0.79
5.36
1.50
3.56
563
659
231
354
20
580
673
246
367
37
TRUE
TRUE
TRUE
TRUE
TRUE
M9:Oxidation(+15.99)
M14:Oxidation(+15.99)
M12:Oxidation(+15.99)
M3:Oxidation(+15.99)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
S5:Phospho(+79.97),M12:
Oxidation(+15.99)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
M10:Oxidation(+15.99)
M4:Oxidation(+15.99)
M6:Oxidation(+15.99)
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
M9:Oxidation(+15.99)
469.7416
937.4676
938.477
2
1.59
734
740
TRUE
787.3684
808.8411
983.4747
565.8019
491.2618
956.0194
552.7932
750.689
838.4602
711.8475
579.3386
445.7589
708.3228
498.7506
1,572.72
1,615.67
1,964.93
1,129.59
980.508
1,910.02
1,103.57
2,249.04
2,512.36
1,421.68
1,156.66
889.5021
1,414.63
995.4855
1,573.72
1,616.67
1,965.93
1,130.60
981.5158
1,911.02
1,104.58
2,250.04
2,513.36
1,422.69
1,157.67
890.51
1,415.63
996.4904
2
2
2
2
2
2
2
3
3
2
2
2
2
2
2.97
1.61
3.81
0.03
0.04
4.30
1.91
3.76
3.85
0.54
0.77
0.09
3.30
2.86
24
1566
584
242
12
174
960
512
52
17
31
499
134
624
36
1579
600
251
19
189
968
530
72
29
41
506
144
632
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
785.9669
795.9636
621.3077
996.0148
520.7758
597.2996
697.8729
454.7488
971.4857
706.3621
1,569.92
1,589.91
1,240.60
1,990.01
1,039.54
1,192.58
1,393.73
907.482
1,940.96
1,410.71
1,570.92
1,590.91
1,241.61
1,991.01
1,040.54
1,193.59
1,394.73
908.4882
1,941.96
1,411.71
2
2
2
2
2
2
2
2
2
2
3.21
5.40
1.70
4.56
1.91
3.10
4.14
1.79
1.91
5.65
180
179
749
354
720
187
217
607
252
855
194
193
758
370
728
197
228
613
268
871
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
2
2
2
2
2
685.3762
1,025.52
898.4414
737.0531
415.7351
493.7861
880.0264
1,368.74
2,049.02
1,794.87
2,208.14
829.4545
985.5566
1,758.04
1,369.74
2,050.02
1,795.87
2,209.14
830.4625
986.5636
1,759.04
2
2
2
3
2
2
2
0.38
3.29
1.99
3.06
0.25
0.90
4.39
199
208
189
848
1718
1718
317
213
226
206
871
1725
1726
332
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
25.3
30
24.5
27.9
28.3
27.4
2
2
2
2
2
2
450.7489
904.4491
777.4396
546.2886
829.4382
733.898
899.4822
2,710.32
1,552.86
1,090.56
1,656.86
1,465.78
900.4904
2,711.33
1,553.87
1,091.57
1,657.87
1,466.79
2
3
2
2
2
2
0.43
2.40
1.36
0.30
1.42
1.69
110
682
191
661
467
97
118
714
205
671
482
110
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
99.5
38.8
66.7
34.3
55.7
90.2
51
49.7
83.6
51.3
100
28.6
28.2
27.7
27.2
28.1
28.1
29.7
29.9
26.8
28.8
28.4
2
2
2
2
2
2
2
2
2
2
2
954.9993
563.2877
588.3126
571.3096
519.2592
820.429
817.0821
558.9467
877.4719
626.3098
937.4915
1,907.98
1,124.56
1,174.61
1,140.60
1,036.50
1,638.84
2,448.22
1,673.82
1,752.93
1,250.60
1,872.97
1,908.99
1,125.57
1,175.62
1,141.61
1,037.51
1,639.84
2,449.22
1,674.82
1,753.93
1,251.61
1,873.97
2
2
2
2
2
2
3
3
2
2
2
2.45
1.88
0.97
0.57
1.27
3.37
3.06
2.65
1.14
2.66
4.84
68
216
458
295
1925
174
1023
202
971
700
343
85
225
468
305
1933
188
1051
216
986
714
359
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
S
D
A
G
G
Q
T
K
85.1
36.3
38.8
72.9
55.2
34.8
62.6
54.6
28.8
28.9
27.6
27.6
29
30.1
27
28.1
2
2
2
2
2
2
2
2
742.3762
630.3832
430.2295
780.9146
702.3527
606.2913
576.2518
632.7869
1,482.74
629.3754
858.4434
1,559.81
1,402.69
1,815.85
1,150.49
1,263.56
1,483.74
630.3828
859.4526
1,560.81
1,403.69
1,816.86
1,151.50
1,264.56
2
1
2
2
2
3
2
2
0.85
0.74
1.59
4.95
3.77
0.22
1.03
2.15
887
394
1227
985
462
1227
251
1963
899
399
1234
1002
476
1242
261
1973
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
K
K
K
K
K
R
R
K
Y
E
G
A
H
V
V
Q
39.7
89.3
36.9
61.7
61.3
68.3
80.9
65.8
22.6
30
27.1
28.8
28
30.3
29.8
23.8
2
2
2
2
2
2
2
2
554.3348
1,015.00
521.7664
781.3466
523.2603
779.3861
858.9146
512.3046
1,106.65
2,027.99
1,041.52
1,560.68
1,044.51
1,556.76
1,715.81
1,022.59
1,107.66
2,028.99
1,042.52
1,561.68
1,045.51
1,557.76
1,716.81
1,023.60
2
2
2
2
2
2
2
2
4.55
2.61
3.78
2.68
2.02
3.47
5.43
2.18
666
2421
816
615
232
38
127
87
675
2437
825
628
240
52
141
95
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
GFLLALPAAVVTPEAASEAYR
GFSGLQGPPGSPGSPGEQGPSGASGPAGPR
GFSSGSAVVSGGSR
GGGGFGGGPGPGGLQSGQTIALPAQGLIEFR
GGGGGGPGSFQPAPR
GGGGPGGEQETQELASK
GGGQIIPTAR
GGGSFVQNNQPVGLR
K
R
R
R
R
R
R
R
A
G
R
D
G
R
R
G
82.5
52.8
118
46.3
69.5
69.4
47.6
81.6
26.1
31.1
29.5
27.9
28.9
29.4
23.5
28.4
2
2
2
2
2
2
2
2
1,073.58
883.0925
627.8074
951.8316
649.8165
801.3762
485.2781
765.3953
2,145.15
2,646.25
1,253.60
2,852.47
1,297.62
1,600.74
968.5405
1,528.77
2,146.16
2,647.25
1,254.61
2,853.47
1,298.62
1,601.74
969.5484
1,529.78
2
3
2
3
2
2
2
2
0.98
4.30
0.55
4.93
0.59
2.16
0.15
0.10
176
1101
23
158
11
26
717
942
196
1130
36
188
25
42
726
956
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M6:Oxidation(+15.99)
M2:Oxidation(+15.99),M8:
Oxidation(+15.99)
M14:Oxidation(+15.99)
M3:Oxidation(+15.99)
M9:Oxidation(+15.99)
M3:Oxidation(+15.99)
M5:Oxidation(+15.99)
M18:Oxidation(+15.99),M20:
Oxidation(+15.99)
830.1267
M18:Oxidation(+15.99),M20:
Oxidation(+15.99),S21:
Phospho(+79.97)
850.1199
701.3538
781.3888
497.7518
1,286.61
722.3837
572.3173
M14:Oxidation(+15.99)
989.4951
979.9985
578.8206
M5:Oxidation(+15.99)
554.2985
623.8406
912.4539
M11:Oxidation(+15.99)
465.2313
1,018.54
644.4343
639.3547
719.9304
M7:Oxidation(+15.99)
677.809
M7:Oxidation(+15.99)
684.8154
796.9332
423.2405
873.9636
3,316.48
3,317.48
4
0.56
592
622
TRUE
3,396.45
1,400.69
2,341.14
993.488
2,571.21
721.3758
1,142.62
1,976.97
1,957.98
1,155.63
1,106.58
1,245.67
1,822.89
1,392.67
2,035.07
643.4265
1,276.69
1,437.85
1,353.60
1,367.62
1,591.85
844.4654
1,745.91
3,397.45
1,401.70
2,342.14
994.4958
2,572.22
722.3838
1,143.63
1,977.97
1,958.98
1,156.63
1,107.59
1,246.67
1,823.89
1,393.68
2,036.06
644.4349
1,277.70
1,438.85
1,354.61
1,368.62
1,592.85
845.4735
1,746.91
4
2
3
2
2
1
2
2
2
2
2
2
2
3
2
1
2
2
2
2
2
2
2
2.49
1.42
3.93
0.04
0.82
0.12
0.35
4.03
3.57
0.56
1.69
3.95
6.11
0.24
9.79
0.89
3.76
2.49
2.91
0.92
2.94
0.24
3.59
592
193
30
1968
273
119
168
768
104
18
111
296
531
274
114
65
334
403
742
761
183
504
129
622
205
53
1977
297
126
178
785
121
29
120
307
547
285
132
70
348
416
752
771
198
511
144
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
672.6684
670.8845
696.3483
711.3837
951.1532
613.8068
2,014.98
1,339.75
1,390.68
1,420.75
2,850.44
1,225.60
2,015.98
1,340.76
1,391.68
1,421.75
2,851.43
1,226.60
3
2
2
2
3
2
3.41
0.06
3.27
3.63
3.40
3.12
133
348
929
580
753
528
149
359
941
594
785
541
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
481.2777
858.4735
431.7562
M2:Oxidation(+15.99),M12:
Oxidation(+15.99)
737.6824
M2:Oxidation(+15.99)
1,060.53
M2:Oxidation(+15.99)
731.833
M2:Oxidation(+15.99)
829.3966
869.9462
678.9902
630.8051
703.8629
484.7644
469.2604
624.8035
533.2774
M6:Oxidation(+15.99)
900.9418
434.7371
645.8297
552.8068
539.2716
814.4393
776.3834
862.885
M11:Oxidation(+15.99)
1,052.49
852.4462
M11:Oxidation(+15.99)
1,051.50
M11:Oxidation(+15.99)
1,065.51
473.2602
540.2907
742.3657
708.385
608.7952
868.4486
1,195.10
610.3209
650.3394
807.9168
711.848
959.0219
775.9163
799.384
1,085.02
800.3746
714.9232
1,101.08
453.2207
588.7864
686.8359
694.3906
771.9321
526.2575
M6:Oxidation(+15.99)
486.7337
915.4702
759.4229
787.4332
580.8272
545.2957
532.2936
960.5397
1,714.93
861.4968
961.5472
1,715.93
862.504
2
2
2
0.29
3.44
0.75
482
61
2326
490
75
2333
TRUE
TRUE
TRUE
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2,210.02
2,119.04
1,461.65
1,656.78
1,737.88
2,033.95
1,259.59
1,405.71
967.5132
936.5052
1,247.59
1,064.54
1,799.87
867.4586
1,289.64
1,103.60
1,076.53
1,626.86
1,550.75
1,723.75
2,102.96
1,702.88
2,100.98
2,129.01
944.5048
1,078.57
1,482.72
1,414.75
1,215.57
1,734.88
2,388.19
1,218.63
1,298.66
1,613.82
1,421.68
1,916.03
1,549.82
1,596.75
2,168.02
1,598.73
1,427.83
2,200.14
904.4258
1,175.56
1,371.66
1,386.77
1,541.85
1,050.50
971.4518
1,828.92
1,516.83
1,572.85
1,159.64
1,088.58
1,062.57
2,211.02
2,120.03
1,462.65
1,657.78
1,738.88
2,034.95
1,260.60
1,406.72
968.5206
937.5109
1,248.60
1,065.54
1,800.87
868.4643
1,290.64
1,104.61
1,077.53
1,627.87
1,551.75
1,724.76
2,103.96
1,703.88
2,101.98
2,130.01
945.5119
1,079.57
1,483.72
1,415.76
1,216.58
1,735.89
2,389.19
1,219.63
1,299.67
1,614.82
1,422.69
1,917.03
1,550.82
1,597.76
2,169.02
1,599.74
1,428.83
2,201.15
905.4329
1,176.56
1,372.66
1,387.77
1,542.85
1,051.51
972.4574
1,829.92
1,517.83
1,573.86
1,160.64
1,089.58
1,063.58
3
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
4.60
4.68
3.87
4.00
5.15
0.74
0.80
0.81
0.48
2.25
2.38
2.33
2.80
2.43
5.33
0.26
2.19
3.17
3.09
0.30
1.58
0.95
0.19
2.48
0.75
2.30
3.65
0.89
1.14
1.50
2.72
1.13
0.97
1.01
1.23
1.10
4.28
0.25
3.34
1.55
4.90
0.15
0.78
0.14
2.34
3.37
4.61
0.96
2.30
4.36
3.24
2.27
3.08
2.50
0.49
538
104
195
610
465
627
152
16
84
1060
130
612
984
1003
405
710
51
1664
838
1016
253
415
241
231
222
300
379
921
28
282
767
320
642
398
457
378
215
52
52
52
150
215
335
389
969
59
50
12
633
630
1405
934
588
675
668
557
123
207
624
480
649
161
28
92
1070
141
624
1003
1011
419
719
60
1677
851
1030
273
430
261
251
229
311
391
933
38
298
788
331
653
414
471
396
228
65
70
65
162
235
342
400
980
71
63
21
641
647
1417
950
601
686
676
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
2
2
657.3428
756.3896
743.3826
757.3981
1,312.67
2,266.15
1,484.75
1,512.78
1,313.67
2,267.15
1,485.76
1,513.79
2
3
2
2
2.82
1.36
1.67
1.48
221
87
435
379
233
106
448
392
TRUE
TRUE
TRUE
TRUE
Irs1
Insulinreceptorsubstrate1
IPI00199662
131160
28
39
93
31.30%
GGHHRPDSSNLHTDDGYMPMSPGVAPVPSNR
R
K
33.2
31.9
2
Irs1
Cald1
Anxa1
Myh10
Kbtbd10
Gsn
Aldh3a1
Eef2
Tubb5
Pygb
Lmod3
Cct6a
Immt
Actbl2
Vcl
Acta1
Col1a2
Atp5a1
Actn1
Actn4
Copa
Ddx3x
Anxa1
IPI00199662
IPI00208118
IPI00231615,IPI00777179
IPI00391300
IPI00190417
IPI00923716
IPI00231064
IPI00203214
IPI00197579
IPI00357945
IPI00568699
IPI00188111,IPI00780515
IPI00364895,IPI00566985
IPI00360356
IPI00365286
IPI00189813
IPI00188921
IPI00396910
IPI00209082,IPI00454431
IPI00213463
IPI00372458
IPI00362534
IPI00231615,IPI00777179
131160
60567
38813
233603
68198
80911
50321
95268
49653
96759
57499
58000
82231
41946
116599
42034
129547
59737
102946
104900
138346
73130
38813
33
15
5
46
8
18
5
5
13
6
9
3
6
2
6
2
13
11
10
28
15
11
7
45
18
5
52
11
23
5
5
14
6
9
3
7
2
6
4
13
12
10
34
15
11
8
88
41
8
210
19
100
10
6
66
6
18
3
7
2
7
23
13
13
10
49
21
20
14
36.00%
33.00%
22.50%
33.80%
18.20%
37.20%
12.40%
7.58%
36.50%
8.51%
23.60%
8.47%
14.00%
22.60%
7.88%
58.60%
12.60%
30.70%
22.60%
39.60%
13.60%
19.30%
31.50%
GGHHRPDSSNLHTDDGYMPMSPGVAPVPSNR
GGNLGENQIKDEK
GGPGSAVSPYPSFNPSSDVAALHK
GGPISFSSSR
GGTGEVNGDVGDEDLLPGYLNDIPR
GGVASGFK
GGVPETTELLK
GHVFEESQVAGTPMFVVK
GHYTEGAELVDSVLDVVR
GIAGLGDVAEVR
GIASMPQFLK
GIDPFSLDALAK
GIEQAVQSHAVAEEEAR
GIHETTFNSIMK
GILSGTSDLLLTFDEAEVR
GILTLK
GIPGPVGAAGATGPR
GIRPAINVGLSVSR
GISQEQMNEFR
GISQEQMQEFR
GITGVDLFGTTDAVVK
GLDISNVK
GLGTDEDTLIEILTTR
R
K
K
R
K
K
K
R
K
R
K
K
R
R
R
R
R
K
K
K
R
R
K
K
I
A
S
H
H
E
A
K
K
E
E
K
C
K
Y
G
V
A
A
H
H
S
30.4
39.6
50.4
74.1
61.2
36.1
34.5
93.9
108
67.3
52.6
43.5
75.3
30.5
76.6
30.8
42.2
25.2
64.7
65.7
71.4
32.9
93.2
31.8
29
30.3
27.2
31
24.5
27.6
29.8
29.4
26.7
28
27.7
29.4
29.4
27.5
19.2
26.2
18.6
29
28.7
27.4
27.2
28.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Pik3cb
Coro2b
Stat1
Col1a2
Col1a1
Col1a1
Insulinreceptorsubstrate1
Caldesmon
AnnexinA1
234kDaprotein
KelchrepeatandBTBdomaincontainingprotein10
Isoform2ofGelsolin
Aldehydedehydrogenase,dimericNADPpreferring
Elongationfactor2
Isoform1ofTubulinbeta5chain
Phosphorylase
similartoleiomodin3
Chaperoninsubunit6a
82kDaprotein
actin,betalike2
Vinculin
Actin,alphaskeletalmuscle
Collagenalpha2(I)chain
ATPsynthasesubunitalpha,mitochondrial
Alphaactinin1
Alphaactinin4
Copaprotein
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked
AnnexinA1
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
similartocoronin,actinbindingprotein,2B
Ab2131
Collagenalpha2(I)chain
collagen,type1,alpha1
collagen,type1,alpha1
IPI00208989
IPI00373332
IPI00213245,IPI00382229,IPI00655247
IPI00188921
IPI00844828
IPI00844828
122595
54948
134593
129547
137936
137936
4
5
4
13
17
17
4
6
4
13
17
17
6
8
4
13
17
17
4.95%
12.30%
4.55%
12.60%
20.90%
20.90%
GLHEFDALKDPEVNEFR
GLIEPISMIVPR
GLNADQLSMLGEK
GLPGEFGLPGPAGPR
GLTGPIGPPGPAGAPGDKGETGPSGPAGPTGAR
GLTGSPGSPGPDGK
K
K
R
R
R
K
R
R
L
G
G
T
29
36.6
40.3
65.4
34.3
47.5
30
24.7
28.7
27.3
29.4
28.3
2
2
2
2
2
2
Agap3
Fdps
Dsp
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
Farnesylpyrophosphatesynthetase
IPI00325147
similartodesmoplakinisoformIisoform2
IPI00366081
58223
40813
332383
9
3
18
13
5
18
43
10
28
19.10%
10.20%
7.79%
GLTPLAYAR
GLTVVQTFQELVEPR
GLVGIEFK
R
R
R
R
K
E
39.8
91.2
36
25.6
26.1
22.4
2
2
2
Arhgef2
Atp5a1
Dpysl3
Dpysl3
Htra1
Hnrpm
Mrlc2
Eno1
Arbp
Col1a2
Lamp1
Emilin1
Col1a1
Col1a2
Col1a1
Clip2
Thbs1
Myh3
Cltc
Lmo7
Krt16
Myh3
Krt42
Krt17
LOC683313
Col1a1
Pdia6
Hip1
Ppp1r12b
Copb2
Lmo7
Nes
Myh3
Pdia6
Cald1
Hnrnpk
Anxa1
Tpm1
Tpm1
Tpm2
Arbp
Myh3
Vim
Lmod2
Thbs1
Anxa1
Anxa2
Flii
Thbs1
Atp1a1
Eprs
Hip1
Col1a1
Col1a1
Eef2
Rhoguaninenucleotideexchangefactor2
IPI00368617
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
Isoform2ofDihydropyrimidinaserelatedprotein3 IPI00203250
Isoform2ofDihydropyrimidinaserelatedprotein3 IPI00203250
HtrAserinepeptidase1,isoformCRA_a
IPI00199325
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
MyosinregulatorylightchainMRLC2
IPI00421625,IPI00564409,IPI00914162
Alphaenolase
IPI00464815,IPI00767147
60SacidicribosomalproteinP0
IPI00200147
Collagenalpha2(I)chain
IPI00188921
Lysosomeassociatedmembraneglycoprotein1
IPI00206336
elastinmicrofibrilinterfacer1
IPI00199867
collagen,type1,alpha1
IPI00844828
Collagenalpha2(I)chain
IPI00188921
collagen,type1,alpha1
IPI00844828
111kDaprotein
IPI00476704
Thrombospondin1
IPI00422076
Myosin3
IPI00201578
Clathrinheavychain1
IPI00193983
LMO7b
IPI00421345
TypeIkeratinKA16
IPI00421793
Myosin3
IPI00201578
Keratin,typeIcytoskeletal42
IPI00421791
Keratin,typeIcytoskeletal17
IPI00370073
Keratin,typeIIcytoskeletal6A
IPI00393340
collagen,type1,alpha1
IPI00844828
proteindisulfideisomeraseassociated6
IPI00365929
huntingtininteractingprotein1
IPI00765689
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
Coatomersubunitbeta'
IPI00231953
LMO7b
IPI00421345
Isoform1ofNestin
IPI00194103
Myosin3
IPI00201578
proteindisulfideisomeraseassociated6
IPI00365929
Caldesmon
IPI00208118
Hnrpkprotein
IPI00194974,IPI00780608
AnnexinA1
IPI00231615,IPI00777179
tropomyosin1,alphaisoformc
IPI00210945
tropomyosin1,alphaisoformc
IPI00210945
Isoform2ofTropomyosinbetachain
IPI00187731
60SacidicribosomalproteinP0
IPI00200147
Myosin3
IPI00201578
Vimentin
IPI00230941
Leiomodin2
IPI00372026
Thrombospondin1
IPI00422076
AnnexinA1
IPI00231615,IPI00777179
IsoformShortofAnnexinA2
IPI00325146
FlightlessIhomolog
IPI00211698
Thrombospondin1
IPI00422076
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
170kDaprotein
IPI00421357,IPI00476855
huntingtininteractingprotein1
IPI00765689
collagen,type1,alpha1
IPI00844828
collagen,type1,alpha1
IPI00844828
Elongationfactor2
IPI00203214
Serine/threonineproteinphosphatasePP1betacatalytic
subunit
IPI00203390
MyosinIc
IPI00393867
Isoform1ofEndoplasmin
IPI00365985
HeatshockproteinHSP90beta
IPI00471584
111895
59737
73882
73882
51312
77613
19821
47111
34198
129547
43952
107542
137936
129547
137936
111364
129653
223846
191585
156634
50760
223846
50196
48106
59233
137936
48743
114988
111371
102535
156634
208776
223846
48743
60567
51012
38813
32831
32831
32941
34198
223846
53716
61700
129653
38813
38662
144843
129653
113040
170072
114988
137936
137936
95268
9
11
5
5
6
5
3
7
6
13
2
11
17
13
13
30
12
60
27
46
4
86
4
16
7
17
4
5
7
3
45
16
69
4
7
4
5
35
25
5
4
60
25
7
19
7
8
9
19
9
9
2
13
13
10
9
12
5
5
7
5
4
7
7
13
2
11
17
13
13
33
12
66
29
58
4
104
5
20
9
17
4
5
7
3
54
17
76
4
7
4
5
57
40
5
4
66
27
7
20
8
11
9
20
9
9
2
13
13
10
9
13
6
6
15
5
5
10
19
13
4
11
17
13
13
42
13
306
29
181
27
217
21
337
82
17
5
7
8
3
120
27
172
5
17
4
8
309
228
8
10
306
64
13
38
14
13
17
38
11
9
3
13
13
17
13.30%
30.70%
12.60%
12.60%
18.10%
10.30%
22.70%
23.70%
29.00%
12.60%
6.63%
15.40%
20.90%
12.60%
14.40%
33.70%
11.70%
39.10%
21.50%
39.90%
15.10%
50.30%
24.10%
34.20%
19.60%
20.90%
13.30%
6.50%
10.60%
3.87%
37.60%
10.50%
42.20%
13.30%
18.60%
15.10%
22.50%
70.80%
48.90%
69.00%
20.80%
39.10%
55.80%
14.20%
17.70%
31.50%
30.10%
8.50%
17.70%
12.10%
7.99%
3.20%
14.40%
14.40%
14.60%
GMFLISSGPPEMYEVHAASR
GMSLNLEPDNVGVVVFGNDK
GMTTVDDFFQGTK
GMYDGPVFDLTTTPK
GNEDIVITVVPEEIDP
GNFGGSFAGSFGGAGGHAPGVAR
GNFNYIEFTR
GNPTVEVDLYTAK
GNVGFVFTK
GPAGPSGPIGK
GPDTVDSTTDIK
GPGAGPGVGGPSR
GPPGPMGPPGLAGPPGESGR
GPSGPQGIR
GPSGPQGPSGAPGPK
GQAQAIEFLK
GQDLSSPAFR
GQEDLKEQLAIVER
GQFSTDELVAEVEK
GQLEDDAVYEDQSQK
GQTGGDVNVEMDAAPGVDLSR
GQTVDQVHHAVNALSK
GQVGGDVNVEMDAAPGVDLSR
GQVGGEINVEMDAAPGVDLSR
GRLDSELR
GRPGPPGSAGAR
GSFSEQGINEFLR
GSLNLTQLQQASR
GSLTEQEPAER
GSNNVALGYDEGSIIVK
GSPAEFSQLQVDDEILAINNTK
GSQASLGFLDPK
GSSFQTVSALFR
GSTAPVGGGSFPNITPR
GSVFSSPSASGTPNK
GSYGDLGGPIITTQVTIPK
GTDVNVFNTILTTR
GTEDELDKYSEALK
GTEDELDKYSEALKDAQEK
GTEDEVEKYSESVK
GTIEILSDVQLIK
GTLEDQIISANPLLEAFGNAK
GTNESLER
GTPGSSPYASPR
GTSQNDPNWVVR
GVDEATIIDILTK
GVDEVTIVNILTNR
GVDLSGNDFK
GVEHAMANK
GVGIISEGNETVEDIAAR
GVLEDIQLNLFTR
GVNQATAAVVASTISGK
GVPGPPGAVGPAGK
GVQGPPGPAGPR
GVQYLNEIK
K
K
K
R
R
R
K
R
R
R
K
R
R
R
R
R
K
R
R
R
R
K
R
R
R
R
K
K
R
R
K
R
K
R
K
R
K
K
K
K
R
K
K
R
K
K
K
R
R
K
K
R
R
R
K
D
L
A
G
K
I
G
E
D
A
G
E
G
G
E
I
R
R
L
I
S
I
I
N
G
E
G
Q
L
F
L
E
E
E
D
S
D
L
D
T
T
Q
Q
H
R
S
G
Q
L
A
S
D
G
D
26.3
57.3
52.8
66.5
32
67.7
55.6
79.7
33.2
27.8
49.6
54.8
93.4
37.8
61.5
62.8
44.3
98.6
71.4
109
103
91.1
113
112
42.4
39.4
76.6
65.2
57.4
68.1
110
58.2
74.7
79.4
85.1
82.3
72.7
80.8
70.6
84.6
64.7
83.8
37.4
46.4
46.4
78
77.6
36.1
34.9
68.3
55.4
118
28.2
39.8
30.7
30.8
30
29.6
30.6
29.1
30.6
28.4
28.8
26.6
26.3
28
27
29.9
25.7
28.5
26.9
27.8
27
29.5
30.2
30.1
28.6
30.4
30.3
27.3
26.4
29.5
27.9
28.5
28.9
29.9
28.7
28.3
28.9
28.8
26.6
27.5
28.8
30.6
29.6
22
28.7
26.7
28.2
29
25.9
25.6
27.4
27.5
29.3
26
27.4
27
28.5
26.8
37170
119797
92756
83266
4
50
4
11
5
65
4
11
5
289
5
23
16.20%
48.90%
6.72%
17.70%
GVSFTFGADVVSK
GVSFYEVPPHLFAVADTVYR
GVVDSDDLPLNVSR
GVVDSEDLPLNISR
R
R
K
R
F
A
E
E
57.3
68.5
88.9
96.8
28
29
28.8
28
Ppp1cb
Myo1c
Tra1
Hsp90ab1
653.3386
646.3311
593.2808
630.7896
694.8369
557.7987
473.249
537.2963
473.2666
537.314
601.8187
574.311
479.2724
854.476
801.0555
625.3134
862.9119
401.7253
946.9276
M8:Oxidation(+15.99)
M9:Oxidation(+15.99)
IPI00209113,IPI00558912
IPI00558912
IPI00421855
IPI00475639
IPI00207038
IPI00200792,IPI00421785
IPI00213463
IPI00454475,IPI00768956,IPI00421812
IPI00768956,IPI00421857,IPI00421812
IPI00391300,IPI00367479,IPI00558912
IPI00421812,IPI00780672,IPI00382153
IPI00454475,IPI00421857
IPI00195673,IPI00475639
IPI00382153
IPI00195673,IPI00475639
IPI00765011,IPI00360356,IPI00189819
IPI00421855
IPI00382153
IPI00197888
IPI00197888
IPI00230775
IPI00210566
Col1a1
Eef1d
Ncl
Ehd2
Hnrnpu
Dsp
Actb
Acta1
Myh10
Myh3
Myh10
Atp5a1
Myh10
Myh10
Lmo7
Clip2
Cltc
Myh9
Myh9
Cltc
Cand1
Myh10
Myh9
Pik3r2
Tmod3
Hsp90ab1
Krt2
Myh10
Myh10
Irs1
Myo1c
Tpm1
Tpm2
Myo1d
Myh9
Rrbp1
Hsp90ab1
Hsp90aa1
collagen,type1,alpha1
Eukaryotictranslationelongationfactor1delta
Nucleolin
EHdomaincontainingprotein2
SP120
similartodesmoplakinisoformIisoform2
Actin,cytoplasmic1
Actin,alphaskeletalmuscle
234kDaprotein
Myosin3
234kDaprotein
ATPsynthasesubunitalpha,mitochondrial
234kDaprotein
234kDaprotein
LMO7b
111kDaprotein
Clathrinheavychain1
Myosin9
Myosin9
Clathrinheavychain1
CullinassociatedNEDD8dissociatedprotein1
234kDaprotein
Myosin9
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
Tropomodulin3
HeatshockproteinHSP90beta
Keratin,typeIIcytoskeletal2epidermal
234kDaprotein
234kDaprotein
Insulinreceptorsubstrate1
MyosinIc
tropomyosin1,alphaisoformc
Isoform2ofTropomyosinbetachain
MyosinId
Myosin9
similartoRibosomebindingprotein1
HeatshockproteinHSP90beta
HeatshockproteinHSP90alpha
IPI00844828
IPI00197900,IPI00471525,IPI00557328
IPI00231827,IPI00882501
IPI00211448
IPI00210090,IPI00566967
IPI00366081
IPI00189819,IPI00765011,IPI00896224
IPI00189813
IPI00391300
IPI00201578
IPI00391300
IPI00396910
IPI00391300
IPI00391300
IPI00421345
IPI00476704
IPI00193983
IPI00209113
IPI00209113
IPI00193983
IPI00205466
IPI00391300
IPI00209113
137936
72252
77259
61221
87731
332383
41720
42034
233603
223846
233603
59737
233603
233603
156634
111364
191585
226326
226326
191585
136349
233603
226326
17
2
7
2
5
11
6
2
70
86
57
11
58
49
38
12
8
105
138
27
12
46
123
17
2
7
2
5
11
12
3
82
104
66
12
67
53
47
12
8
175
222
29
12
52
194
17
2
10
2
7
39
178
9
145
217
435
13
363
157
123
12
8
2139
3511
29
12
210
2027
20.90%
3.69%
12.90%
4.42%
6.64%
5.14%
54.40%
52.30%
45.50%
50.30%
39.20%
30.70%
40.00%
33.40%
31.90%
13.10%
7.10%
47.80%
55.70%
21.50%
12.40%
33.80%
52.30%
GVVGLPGQR
GVVQDLQQAISK
GYAFIEFASFEDAK
GYDFPAVLR
GYFEYIEENK
GYFNEELSEILSDPSDDTK
GYSFTTTAER
GYSFVTTAER
HADQYKEQMEK
HADSAAELAEQIDNLQR
HAEQERDELADEIANSASGK
HALIIYDDLSK
HATALEELSEQLEQAK
HATALEELSEQLEQAKR
HDFGFTIK
HDLETAMHGK
HDVVFLITK
HEAMITDLEER
HEDELLAK
HELIEFR
HEMLPEFYK
HEMPPHIYAISESAYR
HEMPPHIYAITDTAYR
R
R
K
R
R
R
R
R
R
K
R
K
R
R
K
K
K
K
R
K
R
R
R
G
L
E
W
Y
G
E
E
A
V
S
Q
R
F
W
E
Y
L
E
R
T
C
S
33.7
35.9
74.5
37.1
53.1
64.2
81.8
75.2
28.4
105
64
61.6
108
42.5
47.2
29.4
44.2
76.7
58.3
40.2
49.2
54.9
89.7
22
26.4
29.8
27.8
28.2
30.7
27.5
27.1
28.2
29.8
30.3
28
29.2
28.8
27.6
28.8
26.8
28.7
26.9
26.6
28.4
30.6
30.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00554334
IPI00373505
IPI00471584
IPI00551558,IPI00559533
IPI00391300
IPI00391300
IPI00199662
IPI00393867
IPI00210945
IPI00187731
IPI00207989
IPI00209113
IPI00188079
IPI00471584
IPI00210566
81251
39455
83266
69273
233603
233603
131160
119797
32831
32941
116081
226326
143655
83266
84800
26
2
25
6
58
57
14
43
35
4
52
138
12
25
5
30
2
26
9
67
66
14
59
57
5
69
222
12
26
5
83
3
38
175
363
435
31
215
309
14
255
3511
15
38
5
47.20%
5.40%
37.00%
9.48%
40.00%
39.20%
16.30%
45.00%
70.80%
74.30%
53.00%
55.70%
10.90%
37.00%
23.20%
HESLAQYNAK
HFSLAATR
HFSVEGQLEFR
HGDSLKEIK
HGFEAASIK
HGFEAASIKEER
HHLNNPPPSQVGLTR
HHPHFLTHK
HIAEDADR
HIAEDSDR
HIDYFNNQIIVDLVEQQHK
HLAAENR
HLEDLVEK
HLEINPDHPIVETLR
HLEINPDHSIIETLR
R
K
K
K
R
R
R
K
K
K
K
K
K
K
K
L
S
A
M
E
G
R
L
K
K
G
L
L
Q
Q
54.6
40
53.7
39.1
57.3
68.6
82.1
43.2
39.8
37
72.3
46.7
30
64.8
56.6
28.1
26.1
28.5
25.4
27.3
29.3
28.1
28.4
27.5
26.6
28.8
27.2
26.8
26.7
27.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Agap3
Myo1c
Aldh3a1
Irs1
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
MyosinIc
IPI00393867
Aldehydedehydrogenase,dimericNADPpreferring IPI00231064
Insulinreceptorsubstrate1
IPI00199662
58223
119797
50321
131160
9
50
4
31
12
72
4
39
41
328
5
145
19.10%
48.80%
9.93%
31.80%
HLGAHLSR
HLGYKPEEYK
HLTPVTLELGGK
HLVALYTR
R
R
K
K
V
M
S
D
36.2
50.3
43.5
38
27.1
28.5
24
27.1
2
2
2
2
Cltc
P4hb
Acta1
Clathrinheavychain1
Proteindisulfideisomerase
Actin,alphaskeletalmuscle
191585
56935
42034
27
3
2
29
3
4
29
3
23
21.50%
12.40%
58.60%
HNIMDFAMPYFIQVMK
HNQLPLVIEFTEQTAPK
HQGVMVGMGQK
R
K
R
E
I
D
29
26
45.9
30.7
26.4
28
2
2
2
Acta1
Acta1
Acta1
Myo1d
Actn4
Actn1
Actn4
Irs1
Specc1l
Myh9
Myh9
Hsp90ab1
Irs1
Irs1
Irs1
Clip2
Actin,alphaskeletalmuscle
Actin,alphaskeletalmuscle
Actin,alphaskeletalmuscle
MyosinId
Alphaactinin4
Alphaactinin1
Alphaactinin4
Insulinreceptorsubstrate1
CytospinA
Myosin9
Myosin9
HeatshockproteinHSP90beta
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
111kDaprotein
2
2
2
43
28
10
26
28
21
119
132
25
30
31
30
16
4
3
3
53
34
11
29
39
23
194
196
26
40
42
42
16
23
8
8
221
49
13
46
93
36
3095
883
38
85
126
108
16
58.60%
52.80%
52.80%
48.10%
39.60%
23.30%
40.80%
31.30%
25.00%
51.60%
55.20%
37.00%
31.60%
34.10%
29.50%
18.90%
HQGVMVGMGQK
HQGVMVGMGQK
HQGVMVGMGQK
HQVEYLGLLENVR
HRDYETATLSDIK
HRPELIDYGK
HRPELIEYDK
HSAFVPTHSYPEEGLEMHHLER
HSISGPVSTSKPLTALSDKR
HSQAVEELAEQLEQTK
HSQAVEELAEQLEQTKR
HSQFIGYPITLYLEK
HSSETFSAPTR
HSSETFSAPTR
HSSETFSAPTR
HSSPVGRPSIGSASSSVVASASGSK
R
R
R
R
K
R
R
R
R
K
K
K
R
R
R
K
D
D
D
V
A
L
L
R
S
R
V
E
A
A
A
E
46.9
48.9
57.6
77
54
38.9
47.1
55
41.3
114
117
41.5
72.1
30.5
88.8
42.3
28.6
27.8
28
27.5
29.6
27.2
28.6
31
25
29.4
28.2
27.5
27.4
27.1
28.4
29.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
22
28
30
12
7
31
18
44
2
26
34
40
12
7
40
23
55
2
34
49
85
12
11
73
100
144
7.35%
41.70%
39.60%
31.60%
12.40%
14.00%
17.20%
37.20%
47.80%
HTGPNSPDTANDGFVR
HTNYTMEHIR
HTNYTMEHLR
HTQRPGEPEEGAR
HTVDDGLDIR
HVINFDLPSDIEEYVHR
HVLPTSAPDVTSSLPEGK
HVVPNEVVVQR
HYAGDVVYSVIGFIDK
K
K
K
K
K
K
K
K
R
L
V
V
H
K
I
N
L
N
42.5
46.6
46.6
52.4
31.9
64.2
86
56
114
29.7
29
29
29
27.7
29.5
28
25.7
29
2
2
2
2
2
2
2
2
2
27
68
6
58
113
138
4
2
11
2
11
8
22
33
78
7
67
179
222
4
2
11
2
11
8
26
100
99
15
363
1862
3511
4
2
12
2
17
12
34
50.10%
43.10%
18.10%
40.00%
50.90%
55.70%
16.10%
3.69%
15.90%
6.47%
17.00%
5.19%
41.70%
IAEIHESR
IAEKDEEIEQLKR
IAPAVVHIELYR
IAQLEEELEEEQSNMELLNDR
IAQLEEQLDNETK
IAQLEEQLDNETKER
IAQSDYIPTQQDVLR
IASLEVENQNLR
IAYQLAVEAESEQK
IDEPLEGSEDR
IDIIPNPQER
IDLLAQPR
IDQLEGDHQLIQEALIFDNK
R
K
K
R
K
K
R
R
K
K
K
R
K
T
N
K
F
E
Q
T
G
W
I
T
R
H
51
56.5
46.5
69.5
102
38.9
55.7
30.4
93.6
78.5
31.7
51.3
59
26.5
26.6
22.6
31.3
29.5
29
28.5
28.1
28.5
28.5
27.5
21.9
28.4
2
2
2
2
2
2
2
2
2
2
2
2
2
7
2
3
42
86
3
7
2
3
59
104
3
10
3
5
381
217
3
23.70%
4.21%
4.79%
43.80%
50.30%
3.17%
IDQLMIEMDGTENK
IDSLSAQLSQLQK
IDVVVNNAGILR
IDYANLTGISVSSLSDSLFVLHVQR
IEAQNQPFDAK
IEDGISSTLPSK
K
R
R
R
R
R
S
Q
D
E
T
E
74.2
37.4
70.3
65.1
63.1
38
30.1
26.7
22.4
25.7
28.7
28.6
2
2
2
2
2
2
IPI00193983
IPI00198887
IPI00189813
Pik3r2
Myh3
Htra1
Myh10
Myh9
Myh9
Gnai2
Eef1d
Copb2
Hnrnpk
Hsp90ab1
Kab
Actn1
IPI00189813
42034
IPI00189813
42034
IPI00189813
42034
IPI00207989
116081
IPI00213463
104900
IPI00209082,IPI00454431
102946
IPI00213463
104900
IPI00199662
131160
IPI00372846
124324
IPI00209113
226326
IPI00209113
226326
IPI00471584
83266
IPI00199662
131160
IPI00199662
131160
IPI00199662
131160
IPI00476704
111364
IPI00202027,IPI00203088,IPI00464512,I
Isoform1ofHeterogeneousnuclearribonucleoproteinHPI00851133,IPI00851145
49171
Alphaactinin1
IPI00209082,IPI00454431
102946
Alphaactinin4
IPI00213463
104900
Insulinreceptorsubstrate1
IPI00199662
131160
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
258kDaprotein
IPI00392930
257845
Isoform2ofGelsolin
IPI00923716
80911
MyosinId
IPI00207989
116081
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Myosin3
IPI00201578
223846
HtrAserinepeptidase1,isoformCRA_a
IPI00199325
51312
234kDaprotein
IPI00391300
233603
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
GuaninenucleotidebindingproteinG(i),alpha2subunit IPI00231925
40482
Eukaryotictranslationelongationfactor1delta
IPI00197900,IPI00471525,IPI00557328 72252
Coatomersubunitbeta'
IPI00231953
102535
Hnrpkprotein
IPI00194974,IPI00780608
51012
HeatshockproteinHSP90beta
IPI00471584
83266
174kDaprotein
IPI00776774
173996
Alphaactinin1
IPI00209082,IPI00454431
102946
Eno1
Lmna
Hsd17b4
Myo1c
Myh3
Luzp1
Alphaenolase
LaminA
Hsd17b4protein
MyosinIc
Myosin3
leucinezipperprotein1
Hnrph1
Actn1
Actn4
Irs1
Cand1
Ddx3x
Mprip
Gsn
Myo1d
Myh3
Hsp90ab1
Hsp90ab1
Srp72
Myh3
Mvp
Myosin3
HeatshockproteinHSP90beta
HeatshockproteinHSP90beta
similartoSignalrecognitionparticle72kDaprotein
Myosin3
Majorvaultprotein
Capza1
Hspa5
Nexn
Ckap4
Dsp
Ddb1
Hspa5
33kDaprotein
78kDaglucoseregulatedprotein
Isoform1ofNexilin
cytoskeletonassociatedprotein4
similartodesmoplakinisoformIisoform2
DNAdamagebindingprotein1
78kDaglucoseregulatedprotein
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IsoformCofMyosinIb
Alphaenolase
Phosphorylase
MyosinId
111kDaprotein
Elongationfactor1alpha1
IsoformSERCA2BofSarcoplasmic/endoplasmicreticulum
calciumATPase2
ATPsynthasesubunitbeta,mitochondrial
similartoFibulin2precursorisoform1
Proteinphosphatase2(Formerly2A),regulatorysubunitA
(PR65),alphaisoform,isoformCRA_a
234kDaprotein
LMO7b
Tubulinalpha1Bchain
Actin,alphaskeletalmuscle
PolymeraseIandtranscriptreleasefactor
Myosin9
Pik3r2
Myo1b
Eno1
Pygb
Myo1d
Clip2
Eef1a1
Atp2a2
Atp5b
Fbln2
IPI00464815,IPI00767147
IPI00201060
IPI00326948,IPI00561647
IPI00393867
IPI00201578
IPI00324444
47111
74307
81072
119797
223846
119795
M9:Oxidation(+15.99)
M7:Oxidation(+15.99)
M4:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99)
M4:Oxidation(+15.99),M8:
Oxidation(+15.99),M15:
Oxidation(+15.99)
M5:Oxidation(+15.99)
M5:Oxidation(+15.99),M8:
Oxidation(+15.99)
M8:Oxidation(+15.99)
M17:Oxidation(+15.99)
S3:Phospho(+79.97)
T5:Phospho(+79.97)
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
M15:Oxidation(+15.99)
M5:Oxidation(+15.99),M8:
Oxidation(+15.99)
M4:Oxidation(+15.99),M6:
Oxidation(+15.99)
S6:Phospho(+79.97)
S6:Phospho(+79.97)
441.7629
643.3619
797.8803
519.2752
646.2983
1,079.99
566.7678
565.7777
711.8234
940.9595
724.0054
644.3524
898.9591
651.6731
482.7488
577.768
536.3135
680.3142
477.7485
472.2553
605.2866
639.6369
644.3088
881.5101
1,284.71
1,593.75
1,036.53
1,290.58
2,157.96
1,131.52
1,129.54
1,421.63
1,879.90
2,168.99
1,286.69
1,795.90
1,952.00
963.4819
1,153.52
1,070.61
1,358.61
953.4814
942.4949
1,208.56
1,915.89
1,929.90
882.5163
1,285.71
1,594.74
1,037.54
1,291.58
2,158.97
1,132.53
1,130.55
1,422.63
1,880.91
2,170.00
1,287.70
1,796.90
1,953.00
964.4893
1,154.53
1,071.62
1,359.62
954.4898
943.5002
1,209.56
1,916.90
1,930.91
2
2
2
2
2
2
2
2
2
2
3
2
2
3
2
2
2
2
2
2
2
3
3
1.77
3.35
6.15
0.51
3.24
0.07
0.14
0.61
4.57
0.47
0.38
1.55
3.96
0.36
0.36
1.30
0.99
0.69
0.60
2.63
3.16
0.62
0.68
948
466
528
168
230
2402
197
199
1901
1197
1742
306
1238
1238
746
637
270
1025
843
1502
365
185
144
956
477
541
176
239
2420
206
208
1911
1213
1761
316
1253
1254
753
646
278
1035
850
1508
373
200
159
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
580.7888
451.7463
674.8391
513.7835
480.2515
458.5661
556.2986
577.3055
463.7211
471.7185
785.0715
405.7152
491.7654
891.9824
596.3224
1,159.56
901.477
1,347.66
1,025.55
958.4874
1,372.67
1,665.87
1,152.60
925.4266
941.4213
2,352.19
809.4148
981.5151
1,781.95
1,785.94
1,160.57
902.4848
1,348.66
1,026.56
959.4951
1,373.68
1,666.88
1,153.60
926.4333
942.4282
2,353.19
810.4222
982.5211
1,782.95
1,786.95
2
2
2
2
2
3
3
2
2
2
3
2
2
2
3
0.18
0.04
4.10
0.63
0.17
1.01
1.49
1.09
1.23
0.95
2.04
0.57
1.84
3.58
3.37
401
231
320
406
80
80
282
500
153
153
432
861
1097
625
634
410
238
330
414
88
91
296
508
160
160
450
867
1104
639
648
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
445.7519
632.3225
632.8676
486.7858
889.4882
1,262.63
1,263.72
971.556
890.4961
1,263.64
1,264.73
972.5631
2
2
2
2
0.03
0.16
0.51
0.79
333
681
203
82
340
690
214
89
TRUE
TRUE
TRUE
TRUE
678.3194
655.6891
594.288
2,031.93
1,964.04
1,186.56
2,032.93
1,965.04
1,187.57
3
3
2
4.46
3.37
1.37
1589
233
42
1604
249
52
TRUE
TRUE
FALSE
401.8591
594.2891
586.291
785.4243
516.9271
614.3278
433.8954
873.741
521.0393
920.4594
998.5137
603.6609
650.2725
433.8508
610.2893
767.0629
1,202.55
1,186.56
1,170.57
1,568.83
1,547.76
1,226.64
1,298.66
2,618.20
2,080.13
1,838.90
1,995.01
1,807.96
1,298.53
1,298.53
1,218.56
2,298.17
1,203.56
1,187.57
1,171.57
1,569.84
1,548.77
1,227.65
1,299.67
2,619.21
2,081.14
1,839.91
1,996.01
1,808.96
1,299.54
1,299.54
1,219.57
2,299.16
3
2
2
2
3
2
3
3
4
2
2
3
2
3
2
3
0.03
3.22
2.01
1.27
0.13
0.86
0.40
0.81
0.98
1.08
4.79
4.48
0.12
0.06
0.03
4.00
42
42
42
608
438
186
205
569
887
1194
1194
205
1098
1098
1098
16
52
52
52
620
450
195
214
590
906
1209
1210
219
1108
1108
1108
40
FALSE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
562.2627
659.3046
659.3046
732.3535
570.7882
695.0147
917.9838
638.3627
891.9586
1,683.76
1,316.59
1,316.59
1,462.69
1,139.56
2,082.02
1,833.95
1,274.71
1,781.90
1,684.77
1,317.60
1,317.60
1,463.70
1,140.57
2,083.02
1,834.96
1,275.72
1,782.91
3
2
2
2
2
3
2
2
2
2.63
0.40
0.40
0.06
3.03
1.84
2.42
0.22
1.53
99
705
724
768
1073
512
449
127
507
114
714
733
780
1082
528
466
137
522
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
477.755
800.9349
690.9072
850.0659
765.8872
605.9762
873.9592
693.3745
789.9074
630.2922
597.8281
463.2779
780.4036
953.4943
1,599.85
1,379.80
2,547.17
1,529.76
1,814.91
1,745.90
1,384.73
1,577.80
1,258.57
1,193.64
924.5402
2,338.19
954.5009
1,600.85
1,380.80
2,548.17
1,530.77
1,815.91
1,746.90
1,385.74
1,578.80
1,259.58
1,194.65
925.5473
2,339.19
2
2
2
3
2
3
2
2
2
2
2
2
3
1.19
4.45
4.45
3.70
0.82
2.11
4.49
1.70
3.43
0.71
0.07
0.77
2.68
526
1577
179
1775
1817
1817
163
454
656
423
73
1138
685
533
1589
190
1795
1829
1831
177
465
669
433
82
1145
704
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
834.8787
715.8977
641.8784
912.1546
630.8156
623.8306
1,667.74
1,429.78
1,281.74
2,733.44
1,259.62
1,245.65
1,668.75
1,430.79
1,282.75
2,734.44
1,260.62
1,246.65
2
2
2
3
2
2
2.00
1.31
0.51
2.56
0.51
0.03
90
299
93
940
25
243
103
311
104
964
35
254
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
783.0688
909.3554
973.4047
787.9476
744.8588
565.8065
2,346.18
1,816.70
1,944.79
1,573.88
1,487.70
1,129.60
2,347.17
1,817.70
1,945.79
1,574.88
1,488.71
1,130.61
3
2
2
2
2
2
9.64
3.31
5.04
4.99
1.83
0.72
88
250
250
242
1116
745
107
265
266
254
1127
755
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00201578
223846
IPI00471584
83266
IPI00471584
83266
IPI00763992,IPI00766213,IPI00766719 73844
IPI00201578
223846
IPI00231381
96806
IPI00777201,IPI00778882,IPI00780661,I
PI00782724,IPI00869675
33027
IPI00206624
72331
IPI00209938
78377
IPI00365982
63529
IPI00366081
332383
IPI00324451
127044
IPI00206624
72331
60
25
25
3
76
3
66
26
26
3
92
3
306
38
38
3
323
3
39.10%
37.00%
37.00%
7.39%
46.50%
4.71%
IEDMAMLTHLNEPAVLYNLK
IEDVGSDEEDDSGKDK
IEDVGSDEEDDSGKDKK
IEEALQLYNQIIK
IEELEEEIEAER
IEGEGSVLQAK
K
K
K
R
R
R
D
K
K
L
A
L
56.4
55.7
46.4
75.8
92.5
63.2
28.7
27.8
29
24.1
29.3
27.5
2
2
2
2
2
2
8
21
19
11
18
3
15
10
27
22
11
18
3
19
12
59
61
17
28
3
32
45.30%
39.60%
25.80%
25.70%
7.79%
4.47%
28.70%
IEGYDDQVLITEHGDLGNSR
IEIESFFEGEDFSETLTR
IEQDLLEK
IETNENSLESAK
IEVLEEELR
IEVQDTSGGTTALRPSASTQALSSSVSSSK
IEWLESHQDADIEDFK
K
R
R
K
K
R
K
F
A
R
G
L
L
A
28.2
99.4
51.4
58.3
66.2
57.1
31.9
30.3
30.6
27.5
28.8
28
28.8
30.2
2
2
2
2
2
2
2
744.3605
1,075.00
494.2724
667.8267
565.3093
984.835
658.9767
2,230.06
2,147.99
986.5292
1,333.64
1,128.60
2,951.48
1,973.91
2,231.06
2,149.00
987.5365
1,334.64
1,129.61
2,952.48
1,974.91
3
2
2
2
2
3
3
3.35
0.64
0.59
1.22
0.25
4.52
2.86
67
307
128
540
1041
740
602
86
324
135
551
1049
769
617
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00554334
IPI00231045,IPI00331979,IPI00391496
IPI00464815,IPI00767147
IPI00357945
IPI00207989
IPI00476704
IPI00195372,IPI00551729
24
4
7
6
52
30
6
28
4
7
6
69
33
7
88
5
10
6
255
42
18
47.20%
5.10%
23.70%
8.51%
53.00%
33.70%
15.80%
IFEEQGQTQEK
IFLLTNNNLLLADQK
IGAEVYHNLK
IGEGFLTDLSQLK
IGELVGVLVNHFK
IGFPSTSPAK
IGGIGTVPVGR
K
R
R
R
R
R
K
C
S
N
K
S
A
V
72.5
93.6
54
69.7
84.9
41.7
84
28.8
22.7
27.5
27.6
22.2
27
20.3
2
2
2
2
2
2
2
668.8239
865.4962
572.312
710.8892
712.9183
502.7748
513.3093
1,335.63
1,728.98
1,142.61
1,419.76
1,423.82
1,003.53
1,024.60
1,336.64
1,729.99
1,143.62
1,420.77
1,424.83
1,004.54
1,025.61
2
2
2
2
2
2
2
1.03
0.47
0.18
1.14
1.48
0.04
0.08
484
949
184
508
942
289
256
494
963
193
520
954
298
266
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
81251
124908
47111
96759
116081
111364
50096
IPI00190020,IPI00231369
IPI00551812
IPI00365178,IPI00388257
115376
56336
126171
5
2
2
5
2
2
7
2
2
6.70%
4.91%
2.55%
IGIFGQDEDVTSK
IGLFGGAGVGK
IGPAPAFAGDTISLTITK
R
K
R
A
T
G
45.5
38.9
59.9
28.8
25.3
25.2
2
2
2
704.8536
488.2849
886.9979
1,407.69
974.5542
1,771.98
1,408.70
975.563
1,772.98
2
2
2
2.28
0.90
4.36
640
202
1098
652
212
1115
TRUE
TRUE
TRUE
IPI00365423
IPI00391300
IPI00421345
IPI00339167
IPI00189813
IPI00201300
IPI00209113
65306
233603
156634
50134
42034
43891
226326
2
58
38
11
2
4
138
2
67
47
17
3
5
222
2
363
123
69
9
5
3511
6.45%
40.00%
31.90%
37.50%
52.30%
15.80%
55.70%
IGPILDNSTLQSEVKPILEK
IGQLEEQLEQEAK
IGTTSFSQR
IHFPLATYAPVISAEK
IIAPPERK
IIGAVDQIQLTQAQLEER
IIGLDQVAGMSETALPGAFK
K
K
R
R
K
K
R
L
E
S
A
Y
Q
T
24.7
80.5
67
66.3
42.1
96.3
101
19.4
29.1
27.2
25.3
19.2
25.7
28.5
2
2
2
2
2
2
2
732.0872
757.8893
498.7594
878.9874
462.2882
1,013.05
1,017.53
2,194.23
1,514.77
996.5114
1,756.96
923.568
2,025.10
2,034.06
3
2
2
2
2
2
2
5.41
0.27
0.39
1.83
0.57
1.47
0.58
547
1860
1163
265
331
63
618
566
1872
1171
280
338
80
637
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
IPI00209113
IPI00231045,IPI00331979,IPI00391496
IPI00194974,IPI00780608
IPI00208205
IPI00208205
IPI00206624
IPI00200147
IPI00194974,IPI00780608
IPI00421806,IPI00551673
IPI00189813
IPI00207989
IPI00209082,IPI00454431
226326
124908
51012
70855
70855
72331
34198
51012
56489
42034
116081
102946
122
6
3
18
7
15
6
4
12
2
42
22
194
6
3
24
10
19
7
4
18
3
53
26
2067
8
3
59
24
32
19
4
314
21
149
34
51.90%
7.33%
11.60%
39.00%
20.00%
28.70%
29.00%
15.10%
21.30%
54.10%
45.40%
41.70%
IIGLDQVAGMSETALPGAFKTR
IIIAEVVNK
IILDLISESPIK
IINEPTAAAIAYGLDK
IINEPTAAAIAYGLDKK
IINEPTAAAIAYGLDKR
IIQLLDDYPK
IITITGTQDQIQNAQYLLQNSVK
IKEWYEK
IKIIAPPER
ILAAILHLGNLK
ILAGDKNYITGDELR
R
K
K
R
R
R
K
R
K
K
K
K
K
I
G
K
V
E
C
Q
H
K
F
R
28.6
40
65.4
97.1
87.1
77.4
64.8
51.5
47.3
32.4
67.3
23.3
30
20.5
20.9
27.4
23.5
24.4
26.4
24.7
28.2
13.6
9.54
27.6
2
2
2
2
2
2
2
2
2
2
2
2
2,370.17
997.6171
1,339.80
1,658.89
1,786.99
1,815.00
1,216.68
2,588.39
994.5124
1,035.64
1,274.81
1,676.87
2,371.17
998.6252
1,340.80
1,659.90
1,787.99
1,816.00
1,217.68
2,589.39
995.5203
1,036.65
1,275.82
1,677.88
3
2
2
2
2
2
2
3
2
2
2
3
2.64
0.33
3.76
1.05
4.46
7.08
3.94
3.36
0.08
0.43
1.75
0.12
618
929
208
172
172
198
17
434
177
329
270
835
639
937
219
187
188
214
26
456
183
337
281
849
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
IPI00876592
IPI00396910
IPI00780394
IPI00421888,IPI00831745
IPI00390435,IPI00555265
IPI00230941
IPI00230941
102739
59737
98515
75740
75804
53716
53716
11
4
9
2
2
29
28
11
4
9
2
2
39
40
12
6
10
2
2
105
261
19.00%
9.58%
12.90%
2.82%
4.16%
67.20%
62.20%
ILFEVFDENR
ILGADTSVDLEETGR
ILHLLGQEGPK
ILISLATGNR
ILIVGGGVAGLASAGAAK
ILLAELEQLK
ILLAELEQLKGQGK
R
R
R
R
K
K
K
L
V
T
E
S
G
S
33.9
124
32.8
70.1
94.4
70.9
45.4
28.4
29.4
23.3
23.9
19.4
23.2
19.2
2
2
2
2
2
2
2
641.3295
788.3986
602.8579
529.3234
762.9647
585.3613
770.4636
1,280.64
1,574.78
1,203.70
1,056.63
1,523.91
1,168.71
1,538.91
1,281.65
1,575.79
1,204.71
1,057.64
1,524.91
1,169.71
1,539.91
2
2
2
2
2
2
2
2.60
1.57
1.96
1.65
6.51
0.03
5.26
146
59
464
500
230
130
130
155
73
474
509
247
139
143
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Pik3r2
Krt42
Myosin9
IsoformCofMyosinIb
Hnrpkprotein
Heatshockcognate71kDaprotein
Heatshockcognate71kDaprotein
78kDaglucoseregulatedprotein
60SacidicribosomalproteinP0
Hnrpkprotein
Keratin,typeIcytoskeletal10
Actin,alphaskeletalmuscle
MyosinId
Alphaactinin1
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
ATPsynthasesubunitalpha,mitochondrial
Coatomersubunitgamma
AnnexinA6
76kDaprotein
Vimentin
Vimentin
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
Keratin,typeIcytoskeletal42
M10:Oxidation(+15.99)
M10:Oxidation(+15.99),T21:
Phospho(+79.97)
791.0651
499.8164
670.9086
830.4528
894.5034
908.5089
609.3455
863.8045
498.264
518.8297
638.4127
559.9656
2,193.24
1,513.76
995.5032
1,755.96
922.5607
2,024.09
2,033.05
IPI00554334
IPI00421791
81251
50196
24
2
28
3
88
19
47.20%
25.90%
ILLNSER
ILNEMRDQYEK
R
R
L
M
41.5
37.3
27.5
29.3
2
2
Krt16
Tmod3
Ap2a2
Myh3
Thbs1
Atp5b
TypeIkeratinKA16
Tropomodulin3
Adaptorrelatedproteincomplex2,alpha2subunit
Myosin3
Thrombospondin1
ATPsynthasesubunitbeta,mitochondrial
IPI00421793
IPI00373505
IPI00471901
IPI00201578
IPI00422076
IPI00551812
50760
39455
104159
223846
129653
56336
6
8
2
69
19
5
11
10
2
76
20
6
54
18
2
172
38
8
18.40%
34.70%
3.19%
42.20%
17.70%
14.00%
ILNEMRDQYEQMAEK
ILPVFDEPPNPTNVEESLK
ILVAGDTMDSVK
ILYGDFK
IMADSGPIYDK
IMDPNIVGSEHYDVAR
R
K
K
R
K
R
N
R
Q
Q
T
G
37.2
44.3
43.1
32.9
48.8
37.4
30.4
28.5
27.9
24
28.7
30.1
2
2
2
2
2
2
Myh9
Myosin9
IPI00209113
226326
Tubb2a
Tubb5
Atp5b
Actn1
Myo1d
Hnrpm
Tubulinbeta2Achain
IPI00475639
49889
Isoform1ofTubulinbeta5chain
IPI00197579
49653
ATPsynthasesubunitbeta,mitochondrial
IPI00551812
56336
Alphaactinin1
IPI00209082,IPI00454431
102946
MyosinId
IPI00207989
116081
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
77613
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
IPI00208989
122595
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Myosin9
IPI00209113
226326
Myosin3
IPI00201578
223846
Tubulinbeta2Achain
IPI00475639
49889
similartotranslocaseofinnermitochondrialmembrane50
homologisoform2
IPI00766169
39838
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
Ppp2r1a
Myh10
Lmo7
Tuba1b
Acta1
Ptrf
Myh9
Myh9
Myo1b
Hnrnpk
Hspa8
Hspa8
Hspa5
Arbp
Hnrnpk
Krt10
Acta1
Myo1d
Actn1
Nedd4
Atp5a1
Copg
Anxa6
Nnt
Vim
Vim
Pik3cb
Pik3r2
Myh9
Myh3
Tubb2a
LOC687295
Tnnt2
Tnnt3
Kab
Vcl
Vps35
Pik3r2
Myh3
Tpm2
Tpm2
Aldh3a1
Capza2
Krt16
Tubb5
Myh3
Myh3
Myh9
Lmo7
Lmo7
Pik3r1
Tubb6
Tubb5
Kif5b
Cltc
Plod2
Hist4h4
Cand1
Clip2
Actn1
Actn4
Lmo7
Rpn1
Flot1
Vim
Rai14
Kab
Hspd1
Rpn2
Tubb5
Tubb6
Pabpc1
Hspa5
Krt13
Dsp
Hspa5
Cand1
Atp1a1
Ppp1r12b
Myh10
Myh10
IPI00554262,IPI00560341,IPI00829459,I
Isoform1ofTroponinT,fastskeletalmuscle
PI00829466,IPI00829504,IPI00829511 30734
174kDaprotein
IPI00776774
173996
Vinculin
IPI00365286
116599
maternalembryonicmessage3
IPI00869568
91712
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Myosin3
IPI00201578
223846
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Aldehydedehydrogenase,dimericNADPpreferring IPI00231064
50321
Factincappingproteinsubunitalpha2
IPI00370681
32949
TypeIkeratinKA16
IPI00421793
50760
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Myosin3
IPI00201578
223846
Myosin3
IPI00201578
223846
Myosin9
IPI00209113
226326
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
83516
Tubulin,beta6
IPI00195673
50041
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Kinesin1heavychain
IPI00364904
109514
Clathrinheavychain1
IPI00193983
191585
Isoform2ofProcollagenlysine,2oxoglutarate5dioxygenase
2
IPI00208888,IPI00370551
86940
IPI00231340,IPI00364897,IPI00368659,I
PI00559188,IPI00561052,IPI00561706,I
PI00764726,IPI00778180
11464
HistoneH4
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
111kDaprotein
IPI00476704
111364
Alphaactinin1
IPI00209082,IPI00454431
102946
Alphaactinin4
IPI00213463
104900
LMO7b
IPI00421345
156634
Ribophorin1
IPI00204365
68384
Isoform1ofFlotillin1
IPI00208784
47481
Vimentin
IPI00230941
53716
Isoform2ofAnkycorbin
IPI00372146
105981
174kDaprotein
IPI00776774
173996
60kDaheatshockprotein,mitochondrial
IPI00339148
60939
Dolichyldiphosphooligosaccharideprotein
glycosyltransferasesubunit2
IPI00188059
69060
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Tubulin,beta6
IPI00195673
50041
123
194
2027
52.30%
IMGIPEDEQMGLLR
R
V
83
29.3
2
3
13
5
10
28
5
3
14
6
10
31
5
6
49
6
10
48
6
31.70%
36.50%
14.60%
22.60%
30.70%
9.60%
IMNTFSVMPSPK
IMNTFSVVPSPK
IMNVIGEPIDER
IMSIVDPNR
INDIIEVK
INEILSNALK
R
R
R
R
R
R
V
V
G
L
N
R
63.4
64.1
57.8
44.7
63.9
64.2
28.7
27.7
28.8
28.9
25.8
26.3
2
2
2
2
2
2
422.7485
M5:Oxidation(+15.99)
727.8554
M5:Oxidation(+15.99),M12:
Oxidation(+15.99)
965.4384
713.3761
M8:Oxidation(+15.99)
632.8286
428.2347
M2:Oxidation(+15.99)
613.2941
M2:Oxidation(+15.99)
611.2938
M2:Oxidation(+15.99),M10:
Oxidation(+15.99)
817.4008
M2:Oxidation(+15.99),M8:
Oxidation(+15.99)
692.3362
M2:Oxidation(+15.99)
668.3532
M2:Oxidation(+15.99)
701.3561
M2:Oxidation(+15.99)
530.7783
472.2774
557.8287
844.4893
1,454.70
2
2
0.10
5.40
515
262
521
272
TRUE
FALSE
1,929.87
2,138.10
1,264.65
855.4618
1,225.58
1,831.86
2
3
2
2
2
3
0.08
4.87
2.73
0.31
2.32
0.62
274
173
154
714
1131
407
288
191
165
720
1141
422
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
4
4
6
4.77%
INELAIQK
K
R
48.5
24.2
2
464.7774
26
119
76
3
30
194
92
3
71
3095
323
7
47.90%
51.60%
46.50%
32.80%
INEWLGIK
INFDVNGYIVGANIETYLLEK
INQQLDTK
INVYYNEAAGNK
K
R
R
R
N
S
L
Y
37.7
111
48.1
65.4
28
28.2
26.6
28.9
2
2
2
2
486.7814
1,193.12
480.2619
678.3341
971.5472
2,384.23
958.5082
1,354.65
3
3
3
12.50%
IPDEFDSDPILVQQLR
K
R
63.5
27.7
2
942.9951
1,883.97
11
18
45
31.80%
IPDGERVDFDDIHR
K
K
54.3
29.2
2
561.9408
1,682.80
1,683.81
7
8
17
3
10
8
18
3
22
12
25
3
26.30%
5.19%
20.40%
5.15%
IPEGEKVDFDDIQK
IPEQTYITLK
IPTISTQLK
IPVDTYNNILTVLK
K
R
R
K
K
L
I
L
76.4
52.9
32.2
64.7
30.3
26.3
24.1
23.8
2
2
2
2
816.9119
603.343
500.8056
801.9628
1,631.81
1,204.67
999.5956
1,601.91
26
76
3
4
4
4
4
12
77
86
105
39
38
30
92
4
5
4
5
7
12
85
104
175
49
47
83
323
12
14
5
8
29
20
149
217
2139
116
123
47.20%
46.50%
60.20%
74.30%
9.93%
33.20%
15.10%
33.80%
47.90%
50.30%
47.80%
32.70%
31.90%
IQGEYTLTLR
IQLELTQVK
IQLVEEELDR
IQLVEEELDRAQER
IQQLEALQR
IQVHYYEDGNVQLVSHK
IRDWYQR
IREEYPDR
IRELEFELEGEQK
IRELEFELEGEQKR
IRELETQISELQEDLESER
ISAIEPK
ISASLPR
K
R
R
R
R
K
K
K
R
R
K
R
R
K
S
A
L
M
D
Q
I
R
N
A
S
S
62
53.9
75.4
56.6
75.6
41.7
35.3
41.6
28.2
40
106
35.3
37.2
25.5
24
27.3
28.5
23
30.3
27.4
27.7
28.8
27.7
30
23
26.4
2
2
2
2
2
2
2
2
2
2
2
2
2
597.3308
536.3247
622.3298
864.4511
549.8175
677.0125
518.7708
539.2711
540.6161
592.6486
1,159.08
757.4464
743.4417
10
5
13
13
18
11
5
15
13
19
19
12
63
13
19
17.10%
30.20%
36.50%
17.30%
14.40%
ISEIIDSR
ISEQFSAMFR
ISEQFTAMFR
ISFLENNLEQLTK
ISGETIFVTAPHEATAGIIGVNR
R
R
R
K
R
R
R
R
V
K
54.6
66.8
75
38.7
66.8
27.3
28.8
28.7
27
25.4
2
2
2
2
2
5
6
7
8.44%
ISGGYENVPTDDIHMK
R
Q
35.9
30.2
2
3
12
22
11
28
44
4
4
27
43
8
2
3
12
24
13
34
55
5
4
34
50
8
3
6
12
32
20
49
141
5
4
107
62
12
3
24.00%
12.40%
22.20%
27.90%
39.60%
38.90%
11.20%
10.50%
60.90%
48.90%
5.19%
6.81%
ISGLIYEETR
ISGSILNELIGLVR
ISGTTALQEALK
ISIEMHGTLEDQLSHLR
ISIEMNGTLEDQLSHLK
ISINQTPGTK
ISIVVETVYTHVLHPYPTQITQSEK
ISLNTLTLNVK
ISLPLPNFSSLNLR
ISQDADLK
ISQDLALIAR
ISSVQSIVPALEIANAHR
R
K
K
R
R
R
K
R
R
K
R
K
G
S
E
Q
Q
H
Q
S
E
T
E
K
71.6
71.6
84.6
72.4
32.5
51.5
23.9
63.3
106
27.6
80.3
36.4
28.2
20.1
26.6
29.4
29.5
27
24.9
22
23.2
26.9
25.9
24
2
2
2
2
2
2
2
2
2
2
2
2
4
13
5
4
15
5
4
63
16
12.00%
36.50%
27.50%
ISTEVGITNVDLSTVDKDQSIAPK
ISVYYNEATGGK
ISVYYNESSSK
K
R
R
T
Y
K
26.1
66.1
47.4
26.6
28.8
28.8
2
2
2
6
17
2
18
19
12
9
5
57
49
6
18
2
18
20
12
9
5
66
53
9
33
9
28
52
12
11
6
435
157
13.20%
30.90%
14.20%
7.79%
33.50%
12.40%
12.10%
8.86%
39.20%
33.40%
ITGMLLEIDNSELLHMLESPESLR
ITITNDQNR
ITMQNLNDR
ITNLTQQLEQASIVK
ITPSYVAFTPEGER
ITSEALLVTQQLVK
IVEIPFNSTNK
IVEQIPTPAQNTFSASSAR
IVFQEFR
IVGLDQVTGMTETAFGSAYK
K
K
K
K
R
K
K
R
R
R
S
L
L
K
L
V
Y
R
Q
T
64.7
47.7
67.9
74.6
85.9
50.6
38.9
90.3
42.8
122
29.1
28.2
27.5
25.3
29.4
19.5
27.3
28.6
27.4
30.2
5
8
18
3
2
17
3
2
3
18
38
42
4
6
11
19
3
2
27
3
3
3
19
47
50
5
7
19
19
13
3
174
3
21
3
19
123
166
5
8.44%
18.20%
14.40%
18.50%
4.04%
71.50%
4.47%
54.10%
3.99%
14.40%
31.90%
46.10%
13.90%
IVGPEENLSQAEAR
IVIAGGVTEDGLSASVEAFDLK
IVLDNSVFSEHR
IVLEIDNAR
IVLLDSSLEYK
IVTNNLK
IVVFQYSDGK
IWHHTFYNELR
IYEFTLQR
IYIDSNNNPER
IYSSDDILDDGVLPPTVTLSETSYQSER
IYTFIGEVVVSVNPYK
IYVDDGLISLQVK
K
K
K
R
R
K
R
K
K
K
R
R
K
N
T
N
L
K
S
L
V
I
F
L
V
E
71.9
109
57.3
38.2
43.6
33.5
55.5
68
45.8
53.7
28.1
98.8
60.6
28.7
27.4
28.6
25.4
25.1
25.8
27.1
28.9
26.6
28.9
30.8
25.1
24.5
1,632.79
1,633.79
2
0.40
328
341
TRUE
1,382.66
1,334.69
1,400.70
1,059.54
942.539
1,113.64
1,383.67
1,335.70
1,401.70
1,060.55
943.5466
1,114.65
2
2
2
2
2
2
0.50
0.21
0.32
2.45
0.30
2.12
163
163
144
795
359
371
174
174
155
803
366
380
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
927.539
928.547
2
0.09
223
230
TRUE
972.552
2,385.23
959.5163
1,355.66
2
2
2
2
3.18
2.01
0.28
0.66
585
241
444
47
592
261
451
58
TRUE
TRUE
TRUE
TRUE
1,884.97
2
6.11
98
113
TRUE
3
1.50
81
94
TRUE
1,632.81
1,205.68
1,000.60
1,602.91
2
2
2
2
2.12
0.07
1.00
4.36
49
73
988
404
62
82
996
417
TRUE
TRUE
TRUE
TRUE
1,192.65
1,070.63
1,242.64
1,726.89
1,097.62
2,028.01
1,035.53
1,076.53
1,618.82
1,774.92
2,316.15
756.4385
742.4338
1,193.65
1,071.64
1,243.65
1,727.89
1,098.63
2,029.01
1,036.53
1,077.53
1,619.83
1,775.93
2,317.15
757.4461
743.4416
2
2
2
2
2
3
2
2
3
3
2
1
1
0.54
0.08
1.34
0.87
0.19
3.69
0.86
1.39
2.66
0.57
1.97
0.29
0.05
355
1562
92
92
27
194
138
155
1820
1820
1106
247
585
364
1570
101
105
35
210
144
162
1832
1833
1124
253
591
TRUE
TRUE
FALSE
FALSE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
466.7566
616.2929
623.301
774.9202
785.0929
931.4976
1,230.57
1,244.59
1,547.82
2,352.26
932.5053
1,231.58
1,245.59
1,548.83
2,353.25
2
2
2
2
3
0.11
0.03
0.32
3.26
4.84
535
381
381
832
298
542
390
390
844
320
TRUE
TRUE
TRUE
TRUE
TRUE
896.4177
1,790.82
1,791.82
2
2.81
620
635
TRUE
590.8142
742.4497
616.3497
665.6725
648.6642
529.7963
721.3906
608.3698
785.9533
445.236
550.3286
635.693
1,179.61
1,482.88
1,230.68
1,993.99
1,942.97
1,057.58
2,881.53
1,214.72
1,569.89
888.4564
1,098.64
1,904.06
1,180.62
1,483.88
1,231.69
1,995.00
1,943.98
1,058.58
2,882.53
1,215.73
1,570.90
889.4632
1,099.65
1,905.06
2
2
2
3
3
2
4
2
2
2
2
3
0.69
4.55
1.42
2.34
1.02
0.04
3.02
0.33
1.89
1.14
1.59
3.93
48
730
352
656
675
736
126
41
411
241
1296
251
57
743
363
672
691
745
150
51
424
248
1305
268
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
844.1177
651.3231
638.8068
M4:Oxidation(+15.99),M16:
Oxidation(+15.99)
924.8014
537.7819
M3:Oxidation(+15.99)
560.7752
843.478
783.895
771.963
631.3463
1,009.02
469.7593
M10:Oxidation(+15.99)
1,052.52
2,529.33
1,300.63
1,275.60
2,530.33
1,301.64
1,276.61
3
2
2
4.79
0.59
0.07
369
47
47
392
58
57
TRUE
TRUE
TRUE
2
2
2
2
2
2
2
2
2
2
2,771.38
1,073.55
1,119.53
1,684.94
1,565.77
1,541.91
1,260.68
2,016.03
937.503
2,103.02
2,772.38
1,074.55
1,120.54
1,685.94
1,566.78
1,542.91
1,261.68
2,017.04
938.51
2,104.03
3
2
2
2
2
2
2
2
2
2
3.05
1.40
0.36
2.56
1.04
4.69
4.38
2.98
0.95
0.89
581
524
98
1619
61
535
477
399
756
662
604
532
106
1633
74
548
487
417
762
681
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
2
2
2
2
2
2
2
2
2
2
2
756.8892
1,096.08
708.3723
521.799
640.363
801.4838
578.3079
505.9216
535.2875
667.8239
1,034.17
914.5013
731.9152
1,511.76
2,190.15
1,414.73
1,041.58
1,278.71
800.4759
1,154.60
1,514.74
1,068.56
1,333.63
3,099.48
1,826.99
1,461.81
1,512.77
2,191.15
1,415.73
1,042.59
1,279.72
801.4835
1,155.61
1,515.75
1,069.57
1,334.63
3,100.49
1,827.99
1,462.82
2
2
2
2
2
1
2
3
2
2
3
2
2
3.17
1.52
5.89
0.27
2.51
0.35
2.57
0.22
0.99
4.42
0.60
2.89
4.53
359
497
1011
168
238
199
848
87
811
882
415
38
174
372
518
1022
176
248
205
857
97
818
892
442
53
186
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
878.932
1,755.85
1,756.85
2
2.66
178
192
TRUE
853.9255
999.5416
734.8552
730.872
539.6172
619.2971
959.9827
635.3202
791.3903
1,705.84
1,997.07
1,467.69
1,459.73
1,615.83
1,236.58
1,917.95
1,902.94
2,371.15
1,706.84
1,998.06
1,468.70
1,460.73
1,616.84
1,237.59
1,918.95
1,903.94
2,372.16
2
2
2
2
3
2
2
3
3
0.59
6.62
0.47
1.03
0.10
0.82
3.33
2.46
0.34
146
1755
1899
77
77
333
198
217
293
161
1771
1910
90
91
342
214
233
314
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
2,405.10
2,358.15
1,202.61
973.4849
1,357.65
1,142.53
1,256.67
1,242.66
1,387.66
1,219.65
2,367.27
1,757.88
1,108.60
1,205.64
2,177.12
849.4739
1,752.82
1,910.05
1,151.63
815.5118
900.503
1,352.67
1,358.78
2,406.11
2,359.16
1,203.61
974.4909
1,358.66
1,143.54
1,257.68
1,243.66
1,388.67
1,220.65
2,368.26
1,758.88
1,109.61
1,206.65
2,178.12
850.4788
1,753.83
1,911.05
1,152.64
816.5197
901.5109
1,353.67
1,359.79
3
2
2
2
2
2
2
2
2
2
3
2
2
2
3
2
3
3
2
2
2
2
2
0.98
0.17
1.65
1.79
0.66
1.10
0.26
0.85
0.32
0.07
4.60
5.44
1.46
0.68
3.88
3.35
0.58
3.92
0.46
0.10
0.09
5.08
0.66
293
291
866
202
1175
240
1081
1125
1044
1446
1074
367
11
335
207
118
436
624
918
832
1974
1130
351
314
312
875
209
1186
249
1091
1135
1054
1455
1094
382
19
345
226
126
450
639
926
838
1980
1141
363
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Tnnt2
Polyadenylatebindingprotein1
IPI00189074
70683
78kDaglucoseregulatedprotein
IPI00206624
72331
Keratin,typeIcytoskeletal13
IPI00421795
47713
similartodesmoplakinisoformIisoform2
IPI00366081
332383
78kDaglucoseregulatedprotein
IPI00206624
72331
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
111371
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
Isoform2ofProcollagenlysine,2oxoglutarate5dioxygenase
2
IPI00208888,IPI00370551
86940
KelchrepeatandBTBdomaincontainingprotein10 IPI00190417
68198
Clathrinheavychain1
IPI00193983
191585
Keratin,typeIcytoskeletal13
IPI00421795
47713
Tcomplexprotein1subunitgamma
IPI00372388
60630
Isoform1ofTropomyosinbetachain
IPI00230775
32820
DNAdamagebindingprotein1
IPI00324451
127044
Actin,alphaskeletalmuscle
IPI00189813
42034
IsoformCofMyosinIb
IPI00231045,IPI00331979,IPI00391496 124908
Clathrinheavychain1
IPI00193983
191585
LMO7b
IPI00421345
156634
MyosinId
IPI00207989
116081
IsoformM2ofPyruvatekinaseisozymesM1/M2
IPI00339197,IPI00764193
57922
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
14
24
111
37.00%
KALSNMMHFGGYIQK
K
A
41.6
29.8
2
Tnnt3
Myh9
Myh3
Tpm2
Tpm2
Krt10
Actn1
Actn4
Actc1
Isoform1ofTroponinT,fastskeletalmuscle
Myosin9
Myosin3
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
Keratin,typeIcytoskeletal10
Alphaactinin1
Alphaactinin4
Actin,alphacardiacmuscle1
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00209113
226326
IPI00201578
223846
IPI00187731
32941
IPI00187731
32941
IPI00421806,IPI00551673
56489
IPI00209082,IPI00454431
102946
IPI00213463
104900
IPI00194087
42002
12
111
76
3
3
14
13
28
21
16
172
92
4
3
22
17
34
38
46
2414
323
12
8
365
28
49
537
34.40%
50.00%
46.50%
60.20%
63.00%
24.50%
30.80%
39.60%
54.10%
KALSSMGANYSSYLAK
KANLQIDQINTDLNLER
KAQHELEEAEER
KATDAEADVASLNR
KATDAEADVASLNRR
KDAEAWFNEK
KDDPLTNLNTAFDVAER
KDDPVTNLNNAFEVAEK
KDLYANNVLSGGTTMYPGIADR
K
K
R
K
K
R
R
R
R
A
S
A
R
I
S
Y
Y
M
76.5
98
74.9
126
49.4
55.2
69.5
62.6
87
30.1
26.7
28.7
29
28.6
28.1
29.5
29.4
30.4
2
2
2
2
2
2
2
2
2
Acta1
Actb
Myo1c
Myh9
Lmo7
Krt73
Myh9
Myh10
Lmo7
Myh9
Cltc
Cltc
Mprip
Smtn
Rai14
Gsn
Actn1
Hsp90ab1
Myh10
Clip2
Mprip
Thbs1
Clip2
Actin,alphaskeletalmuscle
Actin,cytoplasmic1
MyosinIc
Myosin9
LMO7b
Keratin,typeIIcytoskeletal73
Myosin9
234kDaprotein
LMO7b
Myosin9
Clathrinheavychain1
Clathrinheavychain1
258kDaprotein
smoothelin
Isoform2ofAnkycorbin
Isoform2ofGelsolin
Alphaactinin1
HeatshockproteinHSP90beta
234kDaprotein
111kDaprotein
258kDaprotein
Thrombospondin1
111kDaprotein
IPI00189813
IPI00189819,IPI00765011,IPI00896224
IPI00393867
IPI00209113
IPI00421345
IPI00421780
IPI00209113
IPI00391300
IPI00421345
IPI00209113
IPI00193983
IPI00193983
IPI00392930
IPI00361871,IPI00561311
IPI00372146
IPI00923716
IPI00209082,IPI00454431
IPI00471584
IPI00391300
IPI00476704
IPI00392930
IPI00422076
IPI00476704
42034
41720
119797
226326
156634
60370
226326
233603
156634
226326
191585
191585
257845
99862
105981
80911
102946
83266
233603
111364
257845
129653
111364
2
6
50
132
44
3
138
38
45
113
9
27
35
10
43
17
13
25
58
28
31
19
30
3
12
72
196
55
3
222
44
54
179
9
29
51
10
50
22
17
26
67
31
40
20
33
18
178
328
883
141
7
3511
150
120
1862
10
29
95
13
62
52
28
38
363
43
73
38
42
57.80%
54.40%
48.80%
55.20%
38.90%
9.76%
55.70%
29.70%
37.60%
50.90%
9.01%
21.50%
18.00%
14.40%
48.90%
37.80%
30.80%
37.00%
40.00%
34.30%
17.20%
17.70%
33.70%
KDLYANNVMSGGTTMYPGIADR
KDLYANTVLSGGTTMYPGIADR
KDNYPQSVPR
KDQGELER
KDQGPSEAELER
KDVDAAYMSK
KEEELQAALAR
KEEELQGALAR
KEQEAQEEELR
KFDQLLAEEK
KFDVNTSAVQVLIEHIGNLDR
KFNALFAQGNYSEAAK
KFQANIFNK
KFTSDSPVVAR
KGADLNLVDSLGHNALYYSK
KGGVASGFK
KHEAFESDLAAHQDR
KHLEINPDHPIVETLR
KHQQLLEEK
KIDSLLK
KIEDLQR
KIMADSGPIYDK
KISGTTALQEALK
R
R
K
K
K
K
K
K
R
K
R
R
R
R
K
K
K
K
R
K
K
K
R
M
M
L
Q
Q
V
V
G
K
T
A
V
S
L
L
H
V
Q
N
E
Q
T
E
87.3
97.2
57.3
47.7
87.5
35.9
80.3
62.1
42.3
71.8
42.2
54.2
41.9
40.8
31.9
37.1
64.5
26.1
38.3
29.1
43
40.8
64.4
30.9
30.1
28.5
27.3
29.2
27.3
27.7
27.7
29.2
27.5
25.3
28.5
25.7
27.7
27.8
26.5
29.9
25
26
21.1
26.9
29
23.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Tnnt3
Isoform1ofTroponinT,fastskeletalmuscle
16
46
34.40%
KKEEEELIALK
R
E
66
25.2
2
Isoform2ofTroponinT,cardiacmuscle
Myosin9
Myosin3
Myosin3
234kDaprotein
Myosin9
Myosin3
Isoform1ofTubulinbeta5chain
234kDaprotein
234kDaprotein
Myosin3
Myosin9
Myosin9
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00209113
226326
IPI00201578
223846
IPI00201578
223846
IPI00391300
233603
IPI00209113
226326
IPI00201578
223846
IPI00197579
49653
IPI00391300
233603
IPI00391300
233603
IPI00201578
223846
IPI00209113
226326
IPI00209113
226326
12
Tnnt2
Myh9
Myh3
Myh3
Myh10
Myh9
Myh3
Tubb5
Myh10
Myh10
Myh3
Myh9
Myh9
17
132
68
86
70
113
86
15
70
58
68
107
107
26
196
78
104
82
179
104
16
82
67
78
169
169
111
883
99
217
145
1862
217
69
145
363
99
1242
1242
43.90%
55.20%
43.10%
50.30%
45.50%
50.90%
50.30%
37.60%
45.50%
40.00%
43.10%
49.10%
49.10%
KKEEEELISLK
KKLEMDLK
KKLETDLTQLQSEVEDASR
KKMEGDLNEIEIQLSHANR
KKVDDDLGTIEGLEEAK
KKVEAQLQELQVK
KLAEQELLDSNER
KLAVNMVPFPR
KLDAQVQELHAK
KLDGETTDLQDQIAELQAQVDELK
KLEGDLK
KLEGDSTDLSDQIAELQAQIAELK
KLEMDLK
R
R
K
K
K
R
R
R
K
R
R
R
K
D
D
D
Q
K
F
V
L
V
V
L
M
D
72.8
33.1
38
41.2
27.7
99.3
46.9
32.3
81.1
65.6
28.7
103
41.3
26.7
26.5
28.4
29
28.7
22.7
29
24.8
25.3
28.7
26.8
27.9
27.7
2
2
2
2
2
2
2
2
2
2
2
2
2
Plod2
Kbtbd10
Cltc
Krt13
Cct3
Tpm2
Ddb1
Acta1
Myo1b
Cltc
Lmo7
Myo1d
Pkm2
843.4814
1,453.70
1,928.86
2,137.11
1,263.64
854.4537
1,224.57
1,830.86
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
M15:Oxidation(+15.99)
M5:Oxidation(+15.99)
M5:Oxidation(+15.99)
M6:Oxidation(+15.99),M7:
Oxidation(+15.99)
M6:Oxidation(+15.99)
M15:Oxidation(+15.99)
M9:Oxidation(+15.99),M15:
Oxidation(+15.99)
802.7084
M15:Oxidation(+15.99)
1,180.08
602.311
487.7503
679.832
M8:Oxidation(+15.99)
572.2723
629.3439
622.3358
694.8366
610.8303
790.0964
879.9495
555.3101
603.8276
726.7145
425.7448
585.2809
637.6895
576.8231
408.7637
451.2593
M3:Oxidation(+15.99)
677.3436
680.3969
M5:Oxidation(+15.99)
M3:Oxidation(+15.99)
M6:Oxidation(+15.99)
M4:Oxidation(+15.99)
665.3851
1,328.75
1,329.76
2
0.52
84
94
TRUE
673.3823
510.793
730.7161
561.0393
620.6604
770.9575
515.6028
429.9137
690.389
900.7937
401.7387
1,308.18
446.7442
1,344.75
1,019.57
2,189.12
2,240.13
1,858.96
1,539.90
1,543.78
1,286.72
1,378.76
2,699.36
801.4618
2,614.34
891.4728
1,345.76
1,020.58
2,190.13
2,241.13
1,859.96
1,540.91
1,544.79
1,287.72
1,379.77
2,700.36
802.4677
2,615.34
892.4816
2
2
3
4
3
2
3
3
2
3
2
2
2
0.97
1.65
3.19
1.71
2.71
0.50
0.34
0.41
3.83
2.59
2.41
1.28
1.05
116
1614
1729
1617
1415
1248
1701
252
1293
1096
1055
1052
1615
126
1621
1747
1635
1431
1260
1713
262
1304
1119
1061
1075
1621
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00194087
IPI00210566
IPI00197888
IPI00230775
IPI00765011,IPI00360356,IPI00189819
IPI00765011,IPI00360356,IPI00189819
,IPI00896224,IPI00194087
IPI00765011,IPI00360356,IPI00189819
IPI00765011,IPI00360356,IPI00189819
IPI00213463
IPI00454431,IPI00209082
IPI00765011,IPI00360356,IPI00189819
IPI00206624
IPI00765011,IPI00360356,IPI00189819
IPI00421855
IPI00195673
IPI00197888,IPI00210945,IPI00230775
IPI00197888,IPI00210945,IPI00230775
IPI00782724,IPI00778882,IPI00777201
IPI00421855
IPI00195673,IPI00475639
IPI00475639
IPI00558912
IPI00765011,IPI00189819,IPI00896224
IPI00197888,IPI00210945,IPI00230775
IPI00197888,IPI00210945,IPI00230775
IPI00558912
IPI00391300,IPI00367479,IPI00558912
IPI00213463
IPI00195673,IPI00475639
IPI00558912
IPI00391300
Myh9
Myh3
Ptrf
Vim
Myh9
Tpm1
Tpm1
Tpm2
Myh9
Myh3
Myh9
Krt16
Copb1
Myosin9
Myosin3
PolymeraseIandtranscriptreleasefactor
Vimentin
Myosin9
tropomyosin1,alphaisoformc
tropomyosin1,alphaisoformc
Isoform2ofTropomyosinbetachain
Myosin9
Myosin3
Myosin9
TypeIkeratinKA16
Coatomersubunitbeta
Tnnt3
Rrbp1
Myh9
Myh10
Rai14
Rai14
Myh10
Myh9
Myo1c
Hspa5
Hspa5
Lmo7
Clip2
Myh9
Myh10
Myh10
Irs1
Myh9
Clip2
Mprip
Vim
Vim
Myh9
Isoform1ofTroponinT,fastskeletalmuscle
similartoRibosomebindingprotein1
Myosin9
234kDaprotein
Isoform2ofAnkycorbin
Isoform2ofAnkycorbin
234kDaprotein
Myosin9
MyosinIc
78kDaglucoseregulatedprotein
78kDaglucoseregulatedprotein
LMO7b
111kDaprotein
Myosin9
234kDaprotein
234kDaprotein
Insulinreceptorsubstrate1
Myosin9
111kDaprotein
258kDaprotein
Vimentin
Vimentin
Myosin9
IPI00209113
IPI00201578
IPI00201300
IPI00230941
IPI00209113
IPI00210945
IPI00210945
IPI00187731
IPI00209113
IPI00201578
IPI00209113
IPI00421793
IPI00211812
226326
223846
43891
53716
226326
32831
32831
32941
226326
223846
226326
50760
106996
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00188079
143655
IPI00209113
226326
IPI00391300
233603
IPI00372146
105981
IPI00372146
105981
IPI00391300
233603
IPI00209113
226326
IPI00393867
119797
IPI00206624
72331
IPI00206624
72331
IPI00421345
156634
IPI00476704
111364
IPI00209113
226326
IPI00391300
233603
IPI00391300
233603
IPI00199662
131160
IPI00209113
226326
IPI00476704
111364
IPI00392930
257845
IPI00230941
53716
IPI00230941
53716
IPI00209113
226326
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
138
76
4
32
132
25
28
3
138
68
132
5
14
222
92
4
37
196
40
47
3
222
78
196
10
14
3511
323
4
102
883
228
149
8
3511
99
883
31
15
55.70%
46.50%
15.80%
65.50%
55.20%
48.90%
52.50%
63.00%
55.70%
43.10%
55.20%
16.80%
20.80%
KLEMDLKDLEAHIDTANK
KLETDLTQLQSEVEDASR
KLEVNEAELLR
KLLEGEESR
KLQAQMK
KLVIIESDLER
KLVIIESDLERAEER
KLVILEGELER
KLVWVPSTK
KMEGDLNEIEIQLSHANR
KMQQNIQELEEQLEEEESAR
KNHEEEMLALR
KPITDDDVDR
K
K
K
R
R
R
R
R
K
K
K
K
K
N
D
R
I
D
A
A
S
N
Q
Q
G
I
41.2
66.5
45.1
58.5
36.2
67.6
52.4
65.3
37.2
57.3
88.3
58.1
42.7
28.3
29
25.9
28.1
27.5
24.2
25.7
23.8
23.8
29.5
31.2
28.9
29.3
2
2
2
2
2
2
2
2
2
2
2
2
2
12
12
132
55
43
43
70
105
42
19
21
39
29
138
57
70
38
138
12
31
28
28
132
16
12
196
59
50
50
82
175
59
20
27
49
34
222
66
82
51
222
12
40
40
40
196
46
15
883
166
62
62
145
2139
381
52
59
116
49
3511
435
145
99
3511
12
73
261
261
883
34.40%
10.90%
55.20%
38.10%
48.90%
48.90%
45.50%
47.80%
43.80%
33.50%
39.60%
32.70%
32.40%
55.70%
39.20%
45.50%
40.60%
55.70%
13.10%
17.20%
62.20%
62.20%
55.20%
KPLNIDHLSDDKLR
KPPVSVEPSLDIVSK
KQELEEICHDLEAR
KQELEEILHDLESR
KQHQEVVSVYR
KQLQDELQSQR
KQQQLSALK
KRHEMPPHIYAITDTAYR
KRPETVATQFK
KSDIDEIVLVGGSTR
KSQIFSTASDNQPTVTIK
KSYTSDLQK
KTHDASGQLVHISQELLR
KTLEDEAK
KTTLQVDTLNTELAAER
KVDDDLGTIEGLEEAK
KVDTAAQTNSR
KVEAQLQELQVK
KVEDLQFR
KVEPPTPQEPGPAK
KVESLQEEIAFLK
KVESLQEEIAFLKK
KVIQYLAHVASSHK
R
K
K
K
K
K
K
K
K
K
K
R
R
K
R
K
R
K
R
R
R
R
K
D
L
V
V
M
T
V
S
M
I
V
K
K
T
S
K
L
F
V
M
K
L
S
39
62.6
56.9
56.4
49
55.6
41.3
51.2
52.8
96.3
32
29.3
58.8
29.9
36.3
90
66.3
99.8
56.9
55.2
100
69.6
79.7
27
22.3
29.4
28.3
27.1
27.8
25.7
30
25.6
27.6
27.4
26.7
26.6
27.6
26.7
29.3
28.4
23.7
27.3
27.4
24.4
21.7
23.7
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
M4:Oxidation(+15.99)
700.6971
688.0164
438.5866
530.7861
431.746
657.8875
900.4981
433.5942
529.3247
705.0195
1,239.09
693.346
587.2927
2,099.07
2,061.03
1,312.74
1,059.56
861.4764
1,313.76
1,798.98
1,297.76
1,056.63
2,112.04
2,476.16
1,384.68
1,172.57
2,100.07
2,062.03
1,313.74
1,060.56
862.4822
1,314.76
1,799.99
1,298.77
1,057.64
2,113.04
2,477.15
1,385.68
1,173.58
3
3
3
2
2
2
2
3
2
3
2
2
2
5.08
1.50
0.77
0.38
2.38
2.72
0.83
1.19
0.50
3.77
8.25
0.41
1.90
1615
1730
139
402
1643
168
168
168
30
1618
940
242
603
1632
1747
149
410
1649
178
182
178
38
1635
959
252
612
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
416.7342
797.9603
571.6157
580.3049
686.8723
686.8646
522.3154
554.5333
652.8704
794.9329
655.6832
535.2803
508.7792
467.2488
635.0119
866.4392
595.8129
706.9097
517.7872
737.9002
767.4318
831.4818
790.9525
1,662.91
1,593.91
1,711.82
1,737.89
1,371.73
1,371.71
1,042.62
2,214.10
1,303.73
1,587.85
1,964.03
1,068.55
2,031.09
932.482
1,902.01
1,730.86
1,189.61
1,411.80
1,033.56
1,473.78
1,532.85
1,660.95
1,579.89
1,663.91
1,594.91
1,712.83
1,738.90
1,372.73
1,372.72
1,043.62
2,215.11
1,304.73
1,588.85
1,965.03
1,069.55
2,032.09
933.4895
1,903.01
1,731.87
1,190.61
1,412.81
1,034.56
1,474.79
1,533.85
1,661.95
1,580.89
4
2
3
3
2
2
2
4
2
2
3
2
4
2
3
2
2
2
2
2
2
2
2
0.02
4.54
2.09
0.86
2.16
1.98
1.56
0.62
0.12
2.02
2.19
0.19
0.28
0.43
3.29
2.84
4.24
0.20
2.99
1.10
1.86
4.80
3.81
185
1020
910
954
906
423
846
142
576
353
447
364
853
1174
1798
1416
839
1249
442
161
223
223
186
198
1034
923
967
916
433
854
159
586
367
464
372
870
1181
1814
1431
849
1260
449
174
235
236
199
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
832.4614
M6:Oxidation(+15.99),M17:
Oxidation(+15.99)
775.3647
M8:Oxidation(+15.99)
653.3377
527.788
597.8098
447.7381
453.2644
404.2037
675.0276
773.4533
691.3415
803.4508
764.4298
M9:Oxidation(+15.99)
930.442
515.2837
1,662.91
1,663.91
2
0.90
218
231
TRUE
2,323.07
1,304.66
1,053.56
1,193.60
893.4606
904.5132
806.3918
2,022.06
772.4455
2,071.00
1,604.89
1,526.84
1,858.87
1,542.83
2,324.07
1,305.66
1,054.57
1,194.61
894.4686
905.5208
807.4002
2,023.06
773.4522
2,072.01
1,605.89
1,527.85
1,859.87
1,543.83
3
2
2
2
2
2
2
3
1
3
2
2
2
3
5.74
3.86
0.31
0.17
0.16
0.24
0.71
2.79
1.39
1.84
5.27
1.54
1.20
1.45
796
607
648
286
161
231
174
228
2105
43
192
222
1117
289
815
616
655
294
167
239
180
244
2111
62
206
236
1132
301
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
473.7472
543.3148
565.3095
499.7985
708.8524
647.3801
639.3591
656.3361
632.3516
696.3983
493.7979
794.7532
945.4788
1,084.61
1,128.60
997.5814
1,415.69
1,292.74
1,276.70
1,310.66
1,262.69
1,390.78
985.5802
2,381.24
946.4847
1,085.62
1,129.61
998.5888
1,416.70
1,293.75
1,277.71
1,311.66
1,263.69
1,391.79
986.5887
2,382.23
2
2
2
2
2
2
2
2
2
2
2
3
2.04
0.82
0.36
0.40
0.15
0.54
0.26
1.80
0.32
0.85
0.64
4.17
354
366
405
116
1702
566
424
472
454
457
327
428
361
375
414
124
1713
577
434
482
464
468
335
449
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
TRUE
TRUE
TRUE
964.9887
1,927.96
1,928.96
2
4.26
163
179
TRUE
592.2846
1,073.07
908.4824
753.0493
733.3956
412.2015
608.3416
784.9573
657.6819
405.2242
532.8101
412.2322
744.4616
580.3187
550.8281
626.3395
565.3117
609.8234
586.3203
537.2836
537.2836
644.3731
706.8961
1,182.55
2,144.12
1,814.95
2,256.12
1,464.78
822.3874
1,214.67
1,567.90
1,970.02
808.4328
1,063.60
822.4487
743.4538
1,158.62
1,099.64
1,250.66
1,128.61
1,217.63
1,170.63
1,072.55
1,072.55
643.3653
1,411.78
1,183.56
2,145.11
1,815.95
2,257.13
1,465.78
823.3951
1,215.67
1,568.90
1,971.03
809.441
1,064.61
823.4566
744.4621
1,159.63
1,100.65
1,251.67
1,129.61
1,218.64
1,171.63
1,073.56
1,073.56
644.3733
1,412.78
2
2
2
3
2
2
2
2
3
2
2
2
1
2
2
2
2
2
2
2
2
1
2
0.86
8.95
1.84
0.40
2.94
0.19
1.24
3.53
0.04
0.41
1.64
0.18
0.69
0.18
1.37
1.10
4.36
1.33
0.24
0.15
0.15
0.23
6.51
529
403
102
1062
259
136
282
345
1227
95
95
108
106
253
494
1294
1798
304
33
13
13
180
465
538
424
117
1080
271
142
291
359
1245
101
103
114
112
262
503
1304
1807
315
43
21
21
185
477
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
TRUE
626.2819
659.8787
778.9359
600.3424
558.7993
718.3994
738.8449
844.9403
579.947
566.7797
1,244.13
558.3015
407.7432
804.4063
637.8596
825.426
702.4033
709.9008
406.7352
657.9976
583.296
604.3311
561.7941
569.7908
941.9645
945.4531
673.3368
683.8471
559.7896
889.9482
967.4742
531.2871
1,250.55
1,317.74
1,555.86
1,198.67
1,115.58
717.3915
1,475.67
1,687.86
1,736.82
1,131.54
2,486.25
1,114.59
813.4708
1,606.80
1,273.70
1,648.84
701.3955
1,417.79
811.4548
1,970.97
1,164.58
1,206.65
1,121.57
1,137.57
1,881.91
1,888.89
2,016.99
1,365.68
1,117.56
1,777.88
1,932.93
1,060.56
1,251.55
1,318.75
1,556.86
1,199.68
1,116.59
718.3989
1,476.68
1,688.87
1,737.82
1,132.55
2,487.25
1,115.60
814.4788
1,607.80
1,274.71
1,649.84
702.4039
1,418.79
812.4632
1,971.97
1,165.59
1,207.65
1,122.58
1,138.57
1,882.92
1,889.90
2,017.99
1,366.69
1,118.57
1,778.88
1,933.94
1,061.57
2
2
2
2
2
1
2
2
3
2
2
2
2
2
2
2
1
2
2
3
2
2
2
2
2
2
3
2
2
2
2
2
2.47
0.86
3.87
1.66
0.58
0.65
0.03
1.11
1.99
2.51
5.86
0.03
0.25
1.92
0.32
3.28
0.82
2.95
0.70
3.67
1.12
0.37
0.69
0.61
1.32
0.15
0.74
0.65
1.78
2.22
2.61
0.08
207
683
639
738
843
494
113
1151
845
96
1053
399
370
1227
354
194
71
11
559
1616
441
142
387
388
146
1028
1028
417
676
86
1731
1559
217
693
651
749
852
499
125
1166
858
104
1075
408
376
1241
363
208
76
22
565
1632
449
151
395
396
162
1043
1044
428
685
100
1747
1567
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
548.2634
600.3247
544.2532
608.3019
926.507
719.8666
711.3923
903.5018
807.4257
1,094.51
1,198.63
1,086.49
1,214.59
1,851.00
1,437.72
1,420.77
1,804.99
1,612.84
1,095.52
1,199.64
1,087.49
1,215.59
1,852.00
1,438.72
1,421.77
1,805.99
1,613.83
2
2
2
2
2
2
2
2
2
1.04
2.58
3.51
5.15
5.03
2.49
3.72
4.41
6.68
1602
224
44
44
324
270
357
85
18
1610
233
51
52
339
280
367
101
31
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M6:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M7:Oxidation(+15.99)
M5:Oxidation(+15.99)
Tnnt2
Isoform2ofTroponinT,cardiacmuscle
17
26
111
43.90%
KVLAIDHLNEDQLR
R
E
83.2
26.8
2
Lmo7
Copa
Myo1c
Krt2
Tpm2
Hadhb
Krt42
Krt10
Mprip
Dbn1
Kpnb1
Pdia6
Flii
Lrrfip2
IPI00421345
IPI00372458
IPI00393867
IPI00551558,IPI00559533
IPI00187731
IPI00198467
IPI00421791
IPI00421806,IPI00551673
IPI00392930
IPI00231407,IPI00231784
IPI00204261
IPI00365929
IPI00211698
IPI00373564,IPI00780550
156634
138346
119797
69273
32941
51398
50196
56489
257845
77453
97167
48743
144843
49756
44
15
42
4
4
3
3
14
40
8
8
4
9
6
55
15
59
6
5
3
5
23
54
9
8
4
9
6
141
21
381
146
14
3
19
342
117
21
9
5
17
12
38.90%
13.60%
43.80%
7.58%
74.30%
6.11%
19.70%
21.50%
19.90%
18.70%
13.20%
13.30%
8.50%
16.20%
KWEEAMANAQETGNLVMDVR
KYDEVLHMVR
KYEAFLQR
KYEDEINKR
KYEEVAR
LAAAFAVSR
LAADDFR
LAADDFRLKYENEVALR
LAAEITR
LAASGEGGLQELSGHFENQK
LAATNALLNSLEFTK
LAAVDATVNQVLASR
LAEDILNTMFDPSYSK
LAEEKDELLSQIR
K
R
R
K
R
R
R
R
R
K
K
K
K
K
R
N
Y
T
K
M
T
Q
L
V
A
Y
Q
K
52.4
40.3
57.7
68.6
48.8
70.6
44.3
37.9
32.1
29.1
89.3
93.6
90.1
58.1
30.9
28.4
25.8
28.4
26.1
25.6
26.1
28.1
28.2
30.3
25.6
25.5
30.4
27.5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Nedd4
Kb23
Kb15
Jup
Myh3
Actn1
Krt73
Krt1
Krt76
Krt5
Ckap4
Ckap4
LMO7b
Copaprotein
MyosinIc
Keratin,typeIIcytoskeletal2epidermal
Isoform2ofTropomyosinbetachain
Trifunctionalenzymesubunitbeta,mitochondrial
Keratin,typeIcytoskeletal42
Keratin,typeIcytoskeletal10
258kDaprotein
IsoformAofDrebrin
Importinsubunitbeta1
proteindisulfideisomeraseassociated6
FlightlessIhomolog
Leucinerichrepeatflightlessinteractingprotein2
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
TypeIIkeratinKb23
TypeIIkeratinKb15
Junctionplakoglobin
Myosin3
Alphaactinin1
Keratin,typeIIcytoskeletal73
Keratin,typeIIcytoskeletal1
TypeIIkeratinKb9
Keratin,typeIIcytoskeletal5
cytoskeletonassociatedprotein4
cytoskeletonassociatedprotein4
IPI00876592
IPI00454476,IPI00780672
IPI00207038
IPI00421429
IPI00201578
IPI00209082,IPI00454431
IPI00421780
IPI00421857
IPI00421812
IPI00382153
IPI00365982
IPI00365982
102739
62207
58080
81784
223846
102946
60370
64814
61742
61809
63529
63529
11
2
3
10
86
16
2
9
2
23
11
6
11
2
4
10
104
19
2
14
2
31
11
7
12
3
174
27
217
32
2
298
3
674
17
11
19.00%
5.05%
16.80%
16.60%
50.30%
35.10%
7.59%
15.00%
9.81%
31.10%
25.70%
18.40%
LAEELDTR
LAELEAALQK
LAELEDALQK
LAEPSQLLK
LAEQELLDSNER
LAILGIHNEVSK
LALDIEIATYR
LALDMEIATYR
LALDVEIATYR
LALDVEIATYRK
LALQALTEK
LAMLQEHVESLGPISDLASTVR
R
K
K
R
K
R
K
K
K
K
R
R
L
A
A
S
V
I
K
K
K
L
L
S
48.4
77.8
65.2
53.7
73.8
68.6
81
70.1
95.2
57.2
46
58.8
27.4
26.4
28
21
29.6
22.9
26.2
28.7
26.5
24.9
24.5
26.7
2
2
2
2
2
2
2
2
2
2
2
2
Eno1
Alphaenolase
IPI00464815,IPI00767147
47111
3
3
4
10.40%
LAMQEFMILPVGASSFR
K
E
73.1
29.3
2
Vcl
Pkm2
Mvp
Myh3
Myh3
Krt33a
Actn1
Ap2b1
Cltc
Krt17
Krt17
Krt35
Tpm2
Tubb5
Ppp1r12a
Myh10
Myh3
Flii
Pkm2
Tpm2
Tpm1
Acta1
Emilin1
6
4
3
86
76
9
13
4
10
13
22
4
3
13
6
57
60
8
4
3
27
2
11
6
5
3
104
92
12
17
4
10
17
33
5
3
14
6
66
66
8
4
4
41
3
11
7
5
3
217
323
37
28
4
11
339
468
10
8
66
12
435
306
11
7
12
231
10
11
7.88%
13.90%
4.71%
50.30%
46.50%
23.80%
30.80%
5.15%
8.42%
26.30%
41.10%
12.30%
63.00%
36.50%
7.36%
39.20%
39.10%
7.72%
11.30%
60.20%
50.70%
59.40%
15.40%
LANVMMGPYR
LAPITSDPTEAAAVGAVEASFK
LAQDPFPLYPGEVLEK
LAQESILDLENDKQQLDER
LASADIETYLLEK
LASDDFR
LASDLLEWIR
LASQANIAQVLAELK
LASTLVHLGEYQAAVDGAR
LASYLDK
LASYLDKVR
LASYLEK
LATALQK
LAVNMVPFPR
LAYVAPTIPR
LDAQVQELHAK
LDEAEQLALK
LDFDGLPSGIGK
LDIDSAPITAR
LDKENAIDR
LDKENALDR
LDLAGR
LDLLEEQVAGAVR
R
R
R
K
K
K
K
R
R
R
R
R
R
K
R
K
R
K
R
K
K
R
R
Q
C
D
L
S
T
R
E
K
V
A
V
L
L
R
V
G
L
N
A
A
D
A
69.6
78.7
49.5
58.5
96.1
46.9
54.3
63
46.6
40.8
63.1
48.9
38.9
65.8
48.5
52.4
73.7
53.6
42.6
70.8
70.8
31.4
56
28.7
27.5
28
29.3
27.1
25.3
26.2
23.7
27.8
25.6
24.3
24.9
26.8
27.8
25.8
27.5
27.3
27.8
27.8
27
27
28.8
24.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Dnm2
Myh9
Vcp
Emilin1
Clip2
Myo1c
Tpm2
Myh3
Rai14
Luzp1
Myh9
Krt75
Lrrfip2
Myh3
Nexn
Ehd2
Tpm1
Dbn1
Ncl
Myh9
Krt10
Sdpr
Krt42
Krt15
Ddx3x
Myh3
Myh3
Cald1
Sec31a
Smtn
Myh3
Myh9
Vinculin
IPI00365286
116599
IsoformM2ofPyruvatekinaseisozymesM1/M2
IPI00339197,IPI00764193
57922
Majorvaultprotein
IPI00231381
96806
Myosin3
IPI00201578
223846
Myosin3
IPI00201578
223846
TypeIhairkeratinKA27
IPI00551773
45954
Alphaactinin1
IPI00209082,IPI00454431
102946
Isoform2ofAP2complexsubunitbeta1
IPI00231502,IPI00389753,IPI00781916 105677
Clathrinheavychain1
IPI00193983
191585
Keratin,typeIcytoskeletal17
IPI00370073
48106
Keratin,typeIcytoskeletal17
IPI00370073
48106
TypeIhairkeratinKA30
IPI00421797
50657
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
234kDaprotein
IPI00391300
233603
Myosin3
IPI00201578
223846
FlightlessIhomolog
IPI00211698
144843
IsoformM2ofPyruvatekinaseisozymesM1/M2
IPI00339197,IPI00764193
57922
Isoform2ofTropomyosinbetachain
IPI00187731
32941
tropomyosin1,alphaisoformc
IPI00210945
32831
Actin,alphaskeletalmuscle
IPI00189813
42034
elastinmicrofibrilinterfacer1
IPI00199867
107542
IPI00210319,IPI00389749,IPI00389750,I
Isoform1ofDynamin2
PI00896218
98232
Myosin9
IPI00209113
226326
TransitionalendoplasmicreticulumATPase
IPI00212014,IPI00778228
89519
elastinmicrofibrilinterfacer1
IPI00199867
107542
111kDaprotein
IPI00476704
111364
MyosinIc
IPI00393867
119797
Isoform2ofTropomyosinbetachain
IPI00187731
32941
Myosin3
IPI00201578
223846
Isoform2ofAnkycorbin
IPI00372146
105981
leucinezipperprotein1
IPI00324444
119795
Myosin9
IPI00209113
226326
58kDaprotein
IPI00777617
57763
Leucinerichrepeatflightlessinteractingprotein2
IPI00373564,IPI00780550
49756
Myosin3
IPI00201578
223846
Isoform1ofNexilin
IPI00209938
78377
EHdomaincontainingprotein2
IPI00211448
61221
tropomyosin1,alphaisoformc
IPI00210945
32831
IsoformAofDrebrin
IPI00231407,IPI00231784
77453
Nucleolin
IPI00231827,IPI00882501
77259
Myosin9
IPI00209113
226326
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
56489
Serumdeprivationresponseprotein
IPI00362416
46368
Keratin,typeIcytoskeletal42
IPI00421791
50196
Keratin,typeIcytoskeletal15
IPI00370090
48854
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
Myosin3
IPI00201578
223846
Myosin3
IPI00201578
223846
Caldesmon
IPI00208118
60567
Isoform1ofProteintransportproteinSec31A
IPI00210147,IPI00515833
135256
smoothelin
IPI00361871,IPI00561311
99862
Myosin3
IPI00201578
223846
Myosin9
IPI00209113
226326
4
123
2
11
30
50
4
55
43
3
122
2
4
86
19
2
33
6
6
138
13
6
2
4
9
66
69
10
4
10
47
123
4
194
2
11
33
72
5
62
50
3
194
2
4
104
22
2
59
7
6
222
21
8
3
5
9
79
76
11
4
10
50
194
4
2027
2
11
42
328
14
146
62
3
2067
3
7
217
61
2
252
15
7
3511
430
18
19
8
12
132
172
13
4
13
182
2027
5.28%
52.30%
3.09%
15.40%
33.70%
48.80%
74.30%
37.80%
48.90%
3.17%
51.90%
10.10%
9.84%
50.30%
25.80%
4.42%
65.10%
14.60%
8.26%
55.70%
21.50%
14.90%
25.90%
18.10%
16.30%
42.20%
42.20%
24.30%
3.84%
13.70%
31.50%
52.30%
LDLMDEGTDAR
LDPHLVLDQLR
LDQLIYIPLPDEK
LDTVAGGLQGLR
LEAELEAVSR
LEDTIK
LEEAEKAADESER
LEEAGGVTSTQIELNK
LEEDKDEKINEMTK
LEEEENLTR
LEGDSTDLSDQIAELQAQIAELK
LEGLEDALQK
LEGQVLR
LEIDDLSSSVESVSK
LEINFEQLLR
LEISDEFSEAIGALR
LELAEK
LELLAAYEEVIR
LELQGPR
LEMDLKDLEAHIDTANK
LENEIQTYR
LENNHAQLLR
LEQEIATYR
LEQEISTYR
LEQELFSGGNTGINFEK
LEQQVDDLESSLEQEK
LEQQVDDLESSLEQEKK
LEQYTNAIEGTK
LESEGDSLLR
LESMNDVEELTTLLR
LETDLTQLQSEVEDASR
LEVNLQAMK
K
K
R
R
R
K
K
R
K
K
K
K
R
K
K
K
K
R
R
K
R
R
R
R
R
K
K
R
R
R
K
R
D
C
S
E
K
H
G
K
E
E
M
S
Y
S
Q
G
K
E
G
N
S
R
R
N
Y
K
L
A
T
S
D
A
56
63.7
44.2
60.7
48.6
31
73
106
25.5
35.3
134
65.2
46.4
110
67.2
84.3
33.2
95.5
28.5
33.2
69.4
49.3
60.8
31.2
103
87.5
31.5
70.4
35
68.1
90.3
63.3
28
25.8
25.5
27
28.5
25.3
29.6
28.4
30.1
28.5
29.1
28.4
24.9
29.1
25.8
29.3
26.3
25.5
24.5
29.4
28.2
27.7
28
27.8
29.3
30.4
30.1
29.1
28.1
29.4
30
27.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Myh10
Nes
Irs1
Irs1
Vps35
Ehd2
Akt1
Immt
Atp1b3
234kDaprotein
IPI00391300
Isoform1ofNestin
IPI00194103
Insulinreceptorsubstrate1
IPI00199662
Insulinreceptorsubstrate1
IPI00199662
maternalembryonicmessage3
IPI00869568
EHdomaincontainingprotein2
IPI00211448
RACalphaserine/threonineproteinkinase
IPI00212844
82kDaprotein
IPI00364895,IPI00566985
Sodium/potassiumtransportingATPasesubunitbeta3 IPI00208061
233603
208776
131160
131160
91712
61221
55719
82231
31813
57
16
38
38
3
4
6
6
2
66
17
51
51
3
4
8
7
2
435
27
99
99
3
4
16
7
2
39.20%
10.50%
40.60%
40.60%
5.15%
8.47%
16.00%
14.00%
11.80%
LEVNMQAMK
LEVQQLQADR
LEYYENEK
LEYYENEKK
LFDIFSQQVATVIQSR
LFELEEQDLFR
LFELILMEEIR
LFGMVLGSAPYTVPLPK
LFIYNPTSGEFLGR
R
R
R
R
K
R
K
K
K
A
D
K
W
Q
D
F
K
T
45.5
49.8
37.7
45.1
60.7
92.3
72.1
31.8
34.7
27.4
27.2
27.2
28.8
26.5
29.1
26.4
25.4
28.1
2
2
2
2
2
2
2
2
2
Agap3
Myh3
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
58223
Myosin3
IPI00201578
223846
IPI00231332,IPI00231812,IPI00561761,I
Isoform2ofTroponinT,cardiacmuscle
PI00776952,IPI00780763
34435
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
Coatomersubunitgamma
IPI00780394
98515
Splicingfactorproline/glutaminerich
IPI00627068
75469
Kinesin1heavychain
IPI00364904
109514
methioninetRNAsynthetase
IPI00366397
101566
258kDaprotein
IPI00392930
257845
Vimentin
IPI00230941
53716
Vimentin
IPI00230941
53716
TypeIIkeratinKb9
IPI00421812
61742
Calsequestrin2
IPI00231901
49386
HeatshockproteinHSP90beta
IPI00471584
83266
similartodesmoplakinisoformIisoform2
IPI00366081
332383
Dermcidin
IPI00421832
11266
TypeIIkeratinKb23
IPI00454476,IPI00780672
62207
Hsd17b4protein
IPI00326948,IPI00561647
81072
Isoform2ofAnkycorbin
IPI00372146
105981
similartoHistoneH2Atype1
IPI00559107
18545
8
76
11
92
42
323
17.70%
46.50%
LFLAPLPSSDVPLGQQLLR
LFLWMVTR
K
K
A
I
87.4
57.4
20.8
25.3
2
2
M5:Oxidation(+15.99)
1,032.60
541.2985
2,063.18
1,080.58
2,064.19
1,081.59
2
2
1.50
2.18
400
436
418
443
TRUE
TRUE
M3:Oxidation(+15.99)
586.3308
1,170.65
1,171.66
2
1.11
71
80
TRUE
446.7688
595.8142
904.4605
531.8024
921.5134
651.712
635.7858
556.9369
523.286
721.3872
571.2852
470.7459
730.3864
632.353
769.9672
728.8565
644.4343
891.522
1,189.61
1,806.91
1,061.59
1,841.01
1,952.11
1,269.56
1,667.79
1,044.56
1,440.76
1,140.55
939.4761
1,458.76
1,262.69
1,537.92
1,455.70
643.4264
892.5297
1,190.62
1,807.91
1,062.59
1,842.01
1,953.14
1,270.56
1,668.79
1,045.56
1,441.76
1,141.56
940.4815
1,459.76
1,263.70
1,538.93
1,456.70
644.4349
2
2
2
2
2
3
2
3
2
2
2
2
2
2
2
2
1
0.11
2.90
0.63
2.10
3.53
9.48
0.89
2.80
0.20
6.04
2.07
2.57
0.28
2.45
0.37
1.28
0.98
94
85
291
802
3
756
146
146
358
120
439
2279
83
395
169
478
12
100
94
306
810
21
774
155
158
367
132
448
2286
96
405
183
491
17
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
729.4085
829.0837
565.7957
713.8826
623.3196
501.2672
842.4605
628.8978
570.296
662.3627
722.3578
429.2284
647.8319
978.0087
862.4669
1,456.80
2,484.23
1,129.58
1,425.75
1,866.94
1,000.52
1,682.91
1,255.78
1,138.58
1,322.71
2,164.05
1,284.66
1,293.65
3,908.00
1,722.92
1,457.81
2,485.23
1,130.58
1,426.76
1,867.94
1,001.53
1,683.91
1,256.78
1,139.58
1,323.71
2,165.04
1,285.67
1,294.65
3,909.00
1,723.92
2
3
2
2
3
2
2
2
2
2
3
3
2
4
2
1.11
2.82
2.73
0.66
0.94
0.45
3.50
3.53
2.71
3.16
7.52
0.07
1.07
3.04
1.58
283
282
861
201
520
882
194
668
494
1116
746
337
318
237
706
296
303
870
213
537
890
209
679
503
1128
764
347
328
270
720
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
718.845
546.2828
973.0382
509.7752
482.2981
1,435.67
1,635.83
1,944.06
1,017.53
962.5806
1,436.68
1,636.83
1,945.06
1,018.54
963.588
2
3
2
2
2
0.88
1.07
6.92
0.46
0.48
449
263
228
318
88
459
276
245
326
95
TRUE
TRUE
TRUE
TRUE
TRUE
1,042.65
945.0377
744.445
1,041.64
1,888.06
1,486.87
1,042.65
1,889.07
1,487.88
1
2
2
1.09
1.25
1.67
712
285
230
720
300
243
TRUE
TRUE
TRUE
Tnnt2
Pik3ca
Copg
Sfpq
Kif5b
Mars
Mprip
Vim
Vim
Krt76
Casq2
Hsp90ab1
Dsp
DCD
Kb23
Hsd17b4
Rai14
LOC682649
Agap3
Ppp1r12b
Eif3c
Hnrpm
Smtn
Myo1c
Pck2
Cand1
Tra1
Fn1
Qars
Lmod2
Tmod3
Vim
Specc1l
Pik3r1
Tubb5
Cltc
Ppp1r12b
Tra1
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
Eukaryotictranslationinitiationfactor3subunitC
IPI00914189
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
smoothelin
IPI00361871,IPI00561311
MyosinIc
IPI00393867
phosphoenolpyruvatecarboxykinase2
IPI00869844
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
Isoform1ofEndoplasmin
IPI00365985
Isoform1ofFibronectin
IPI00200757,IPI00231982,IPI00231983
GlutaminyltRNAsynthetase
IPI00362720
Leiomodin2
IPI00372026
Tropomodulin3
IPI00373505
Vimentin
IPI00230941
CytospinA
IPI00372846
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
Isoform1ofTubulinbeta5chain
IPI00197579
Clathrinheavychain1
IPI00193983
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
Isoform1ofEndoplasmin
IPI00365985
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
huntingtininteractingprotein1
IPI00765689
Tubulinalpha1Bchain
IPI00339167
Pik3ca
Hip1
Tuba1b
LOC682005;G
apdh;LOC685
186
Glyceraldehyde3phosphatedehydrogenase
Kif5b
Kinesin1heavychain
neuralprecursorcellexpressed,developmentallydown
Nedd4
regulatedgene4
Lmna
LaminA
Myh9
Myosin9
Myh9
Myosin9
Tpm2
Isoform2ofTropomyosinbetachain
Rai14
Isoform2ofAnkycorbin
Cald1
Caldesmon
Coro2b
similartocoronin,actinbindingprotein,2B
Myh14
myosin,heavychain14
Tpm1
tropomyosin1,alphaisoformc
Tpm1
tropomyosin1,alphaisoformc
Tpm2
Isoform2ofTropomyosinbetachain
Tpm2
Isoform2ofTropomyosinbetachain
Myh9
Myosin9
Cald1
Caldesmon
Myh9
Krt13
Krt10
Mprip
Myh3
Myh3
Rrbp1
Vcl
Pik3r1
Dsp
Krt17
Kb23
Vim
Clathrinheavychain1
Alphaactinin1
Importinsubunitbeta1
smoothelin
elastinmicrofibrilinterfacer1
Stress70protein,mitochondrial
MyosinIc
MyosinIc
MyosinIc
isoleucyltRNAsynthetase
Coatomersubunitgamma
Factincappingproteinsubunitalpha2
LOC680312
Jup
Rai14
Hspa8
Mprip
Vim
histoneH2B
Junctionplakoglobin
Isoform2ofAnkycorbin
Heatshockcognate71kDaprotein
258kDaprotein
Vimentin
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
Ddx5
cytoskeletonassociatedprotein4
FlightlessIhomolog
MyosinIc
Keratin,typeIIcytoskeletal1
Keratin,typeIIcytoskeletal2epidermal
Isoform2ofAP2complexsubunitbeta1
similartocoronin,actinbindingprotein,2B
111kDaprotein
111kDaprotein
Nedd4
Ddx5
Ckap4
Flii
Myo1c
Krt1
Krt2
Ap2b1
Coro2b
Clip2
Clip2
24
111
37.00%
LFMPNLVPPK
R
I
48.5
27.2
2
17
9
3
13
2
54
37
40
2
5
15
18
6
8
4
39
2
28
10
3
13
2
117
102
261
3
8
29
28
61
49
4
61
7
18.40%
12.90%
6.01%
17.30%
3.55%
19.90%
65.50%
62.20%
9.81%
12.60%
24.60%
7.79%
35.50%
11.40%
6.79%
36.40%
8.93%
LFQPFLK
LFQSNDPTLR
LFVGNLPADITEDEFK
LFVQDLATR
LFVSEGSPGSLPVLAAAAR
LGDAAAELAIKEQALAKLK
LGDLYEEEMR
LGDLYEEEMRELR
LGELQTTAGR
LGFSEEGSLYVLK
LGIHEDSTNR
LGIYEAMK
LGKDAVEDLESVGK
LGLDIEIATYR
LGLLGLANTLVIEGR
LGLLSHESADGDSR
LGLTIK
R
K
R
K
R
R
R
R
K
R
K
K
K
K
K
K
R
V
R
R
V
A
G
E
R
H
G
R
I
G
R
K
L
I
34.7
55.4
62.3
45
63.2
30.5
52.5
28.5
41.7
49
61.1
35.1
79.5
76
90.3
73
28.9
24.8
28.6
29.2
27.6
24.7
20
27.9
29.7
27
27
28
27.3
28.4
26.7
18.9
28.8
19.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
58223
111371
105420
77613
99862
119797
70725
136349
92756
272486
87683
61700
39455
53716
124324
9
5
6
9
7
40
3
12
9
8
2
6
3
36
12
12
5
6
9
7
53
3
12
9
9
2
7
3
48
13
41
6
6
11
7
252
3
12
9
12
2
9
4
124
18
19.10%
8.86%
8.89%
16.70%
9.88%
44.00%
6.56%
12.40%
16.70%
4.68%
4.52%
12.80%
9.94%
74.00%
15.00%
LGNQSTALAVQTVR
LGQTPFDVADEGLVEHLEMLQK
LGSLVENNER
LGSTVFVANLDYK
LGSVTHVTTFSHASPGNR
LGTEEISPR
LGTHVLQALGDGDFIK
LGTLSALDILIK
LGVIEDHSNR
LGVRPSQGGEAPR
LGYFSVDPDSHQGQVVFNR
LGYHFELPGPR
LGYQFTQQGPR
LHDEEIQELQAQIQEQHVQIDVDVSKPDLTAALR
LHDNLIISDLENTVK
R
K
K
R
R
R
R
K
K
K
R
R
K
K
K
T
K
V
V
G
V
C
N
T
E
T
M
T
D
K
101
32.9
33.1
64.1
46.1
66.5
36.9
51.7
67.8
41.6
28.6
44.9
78.5
55.1
77.9
25.4
29.8
27.3
27.6
29
27.2
26.6
17
28
27.1
29.9
28.1
28.7
26.7
27.5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
83516
49653
191585
111371
92756
10
13
18
7
4
11
14
19
7
4
19
49
19
8
5
17.10%
36.50%
14.40%
10.60%
6.72%
LHEYNTQFQEK
LHFFMPGFAPLTSR
LHIIEVGTPPTGNQPFPK
LIESDLNSK
LIINSLYK
K
R
K
K
K
S
G
K
F
N
47.7
49.4
78.4
32.4
28.2
29.1
29.5
25.3
27.8
19
2
2
2
2
2
124233
114988
50134
15
3
11
17
3
13
28
7
41
18.40%
4.47%
34.60%
LINLTDILK
LIQIPQLPENPPNFLR
LISQIVSSITASLR
K
R
R
Q
A
F
49.5
69.2
90.7
22.9
23.2
21.8
2
2
2
IPI00555252,IPI00567177
IPI00364904
35810
109514
9
13
12
13
51
13
34.80%
17.30%
LISWYDNEYGYSNR
LITDLQDQNQK
K
K
V
M
83.4
62.7
29.8
29.2
2
2
IPI00876592
IPI00201060
IPI00209113
IPI00209113
IPI00187731
IPI00372146
IPI00208118
IPI00373332
IPI00367479
IPI00210945
IPI00210945
IPI00187731
IPI00187731
IPI00209113
IPI00208118
102739
74307
226326
226326
32941
105981
60567
54948
229088
32831
32831
32941
32941
226326
60567
11
2
119
138
4
43
15
5
2
29
25
3
5
138
15
11
2
194
222
5
50
15
5
2
48
40
4
6
222
18
12
3
3095
3511
14
62
27
6
19
160
228
12
13
3511
41
19.00%
3.91%
51.60%
55.70%
74.30%
48.90%
29.80%
11.50%
4.25%
62.30%
48.90%
64.80%
71.80%
55.70%
33.00%
LITLHDMESVDSEYYSSLR
LKDLEALLNSK
LKDVLLQVEDER
LKDVLLQVEDERR
LKEAETR
LKEALNSLSQLSYSTSSSK
LKEEIER
LKEELAQK
LKEVVLQVDEERR
LKGTEDELDK
LKGTEDELDKYSEALK
LKGTEDEVEK
LKGTEDEVEKYSESVK
LKQMEDEKNSFR
LKQTENAFSPSR
K
R
K
K
K
K
R
R
R
K
K
K
K
K
K
W
E
R
N
A
R
R
D
V
Y
D
Y
D
E
S
24.7
42.7
84.9
67.5
47.5
55.8
37.5
39.1
39.7
48.8
63
56.5
49.9
57.3
48.2
30.5
24.1
26.4
24.4
27.5
27.7
26.8
25.1
24.4
28.6
28.7
28.8
29.5
29.7
27.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
226326
47713
56489
257845
223846
223846
143655
116599
122
2
14
37
86
47
3
17
194
2
22
49
104
50
3
18
2067
4
365
105
217
182
3
25
51.90%
18.30%
24.50%
19.50%
50.30%
31.50%
2.71%
20.40%
LKSMEAEMIQLQEELAAAER
LKYENELALR
LKYENEVALR
LLAEETAATISAIEAMK
LLAHLYATFATTDADGGK
LLASIDIDHTQYK
LLATEQEDAAVAK
LLAVAATAPPDAPNREEVFDER
K
R
R
R
R
K
K
K
A
Q
Q
N
K
F
S
A
60.2
53.3
59.8
118
74
68.1
32.1
34.2
30.5
26.2
27.1
28.1
29.2
28.1
28.3
29
2
2
2
2
2
2
2
2
83516
332383
48106
62207
53716
7
18
22
11
38
8
18
33
14
51
10
28
468
39
155
9.67%
7.79%
41.10%
13.30%
77.50%
LLEAIEK
LLEAQIATGGIIDPK
LLEGEDAHLTQYK
LLEGEEQR
LLEGEESR
K
R
R
R
K
K
E
P
L
I
30.9
96.4
52.2
52.6
50
26.3
23.1
28.8
27.8
26.9
2
2
2
2
2
Myosin9
IPI00209113
Keratin,typeIcytoskeletal13
IPI00421795
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
258kDaprotein
IPI00392930
Myosin3
IPI00201578
Myosin3
IPI00201578
similartoRibosomebindingprotein1
IPI00188079
Vinculin
IPI00365286
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
similartodesmoplakinisoformIisoform2
IPI00366081
Keratin,typeIcytoskeletal17
IPI00370073
TypeIIkeratinKb23
IPI00454476,IPI00780672
Vimentin
IPI00230941
Cltc
Actn1
Kpnb1
Smtn
Emilin1
Hspa9
Myo1c
Myo1c
Myo1c
Iars
Copg
Capza2
14
15
9
3
13
2
40
32
28
2
4
15
18
4
8
4
31
2
IPI00193983
191585
IPI00209082,IPI00454431
102946
IPI00204261
97167
IPI00361871,IPI00561311
99862
IPI00199867
107542
IPI00363265
73840
IPI00393867
119797
IPI00393867
119797
IPI00393867
119797
IPI00365783
144271
IPI00780394
98515
IPI00370681
32949
IPI00190348,IPI00209163,IPI00388454,I
PI00393508,IPI00480852,IPI00551802,I
PI00556932,IPI00560461,IPI00560818,I
PI00734783,IPI00764164,IPI00766320,I
PI00768311,IPI00870721
13873
IPI00421429
81784
IPI00372146
105981
IPI00208205
70855
IPI00392930
257845
IPI00230941
53716
9
13
8
7
11
8
50
37
50
2
9
3
9
17
8
7
11
8
65
45
72
2
9
3
10
28
9
7
11
9
289
110
328
2
10
6
9.01%
30.80%
13.20%
9.88%
15.40%
15.90%
48.90%
41.10%
48.80%
1.51%
12.90%
17.80%
LLEMNLMHAPQVADAILGNQMFTHYDR
LLETIDQLYLEYAK
LLETTDRPDGHQNNLR
LLEVTADLAER
LLGGQAGLGR
LLGQFTLIGIPPAPR
LLGVEGTTLR
LLHYAGEVTYSVTGFLDK
LLHYAGEVTYSVTGFLDKNNDLLFR
LLIDPASIR
LLLLDTVTMQVTAR
LLLNNDNLLR
R
K
K
K
K
K
R
R
R
K
R
R
A
R
S
R
R
G
E
N
N
D
S
E
30.4
94.5
30.2
45.4
36.2
60.4
77.2
87.7
35
30.8
82.5
81.6
31.9
27.1
28.8
26.4
22.6
16.2
24.8
28.6
27.9
21.6
23.7
23.8
2
2
2
2
2
2
2
2
2
2
2
2
2
10
29
16
33
28
2
10
35
19
42
40
4
27
51
59
71
261
19.00%
16.60%
36.10%
33.30%
17.40%
62.20%
LLLPGELAK
LLNDEDPVVVTK
LLQAVENGDAEK
LLQDFFNGK
LLQDQLR
LLQDSVDFSLADAINTEFK
R
K
R
K
R
R
H
A
V
E
V
N
30.2
69.8
66.7
57.5
43.5
147
16.3
26.8
28
28.3
24.6
28.8
2
2
2
2
2
2
IPI00876592
IPI00464718
IPI00365982
IPI00211698
IPI00393867
IPI00421857
IPI00551558,IPI00559533
IPI00231502,IPI00389753,IPI00781916
IPI00373332
IPI00476704
IPI00476704
11
3
11
8
43
7
5
4
5
22
8
11
3
11
8
59
11
8
4
6
24
8
12
6
17
11
215
386
206
4
8
32
10
19.00%
5.04%
25.70%
7.72%
45.00%
12.20%
9.33%
5.15%
12.30%
22.20%
8.92%
LLQFVTGTSR
LLQLVEDR
LLQSEESSSR
LLQSLLDTR
LLQSNPVLEAFGNAK
LLRDYQELMNTK
LLRDYQELMNVK
LLSTDPVTAK
LLTTGVSR
LLVAENR
LLVENVR
R
K
K
R
R
R
R
R
R
K
R
V
G
L
C
T
L
L
E
W
L
K
68.3
64.5
59.2
61.9
86.8
52.3
51.8
35.8
47.9
30.3
29.8
24.7
24.9
28
24.8
26.4
28.3
28
27
25.1
24.8
24.6
2
2
2
2
2
2
2
2
2
2
2
102739
69223
63529
144843
119797
64814
69273
105677
54948
111364
111364
Agap3
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
Agap3
Cltc
Arhgef2
Rai14
Actn1
Rpn2
Htra1
Rai14
Vim
ArfGAPwithGTPasedomain,ankyrinrepeatandPHdomain3IPI00870084
58223
Clathrinheavychain1
IPI00193983
191585
Rhoguaninenucleotideexchangefactor2
IPI00368617
111895
Isoform2ofAnkycorbin
IPI00372146
105981
Alphaactinin1
IPI00209082,IPI00454431
102946
IPI00557424,IPI00764064,IPI00776515,I
70kDaprotein
PI00782066
69603
MyosinId
IPI00207989
116081
CytospinA
IPI00372846
124324
similartoFibulin2precursorisoform1
IPI00365178,IPI00388257
126171
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
170kDaprotein
IPI00421357,IPI00476855
170072
EHdomaincontainingprotein2
IPI00211448
61221
Hsd17b4protein
IPI00326948,IPI00561647
81072
MyosinId
IPI00207989
116081
Insulinreceptorsubstrate1
IPI00199662
131160
SP120
IPI00210090,IPI00566967
87731
TypeIhairkeratinKA27
IPI00551773
45954
kelchrepeatandBTB(POZ)domaincontaining5
IPI00371293
67154
Junctionplakoglobin
IPI00421429
81784
Coatomersubunitbeta'
IPI00231953
102535
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Coatomersubunitbeta'
IPI00231953
102535
similartoglycyltRNAsynthetase
IPI00364262,IPI00766072
88083
Elongationfactor1alpha1
IPI00195372,IPI00551729
50096
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
Dolichyldiphosphooligosaccharideprotein
glycosyltransferasesubunit2
IPI00188059
69060
HtrAserinepeptidase1,isoformCRA_a
IPI00199325
51312
Isoform2ofAnkycorbin
IPI00372146
105981
Vimentin
IPI00230941
53716
Vim
Myh3
Myh3
Myh3
Cald1
Clip2
Vim
Vim
Myh10
Myh9
Myh3
Clip2
Myh9
Vimentin
Myosin3
Myosin3
Myosin3
Caldesmon
111kDaprotein
Vimentin
Vimentin
234kDaprotein
Myosin9
Myosin3
111kDaprotein
Myosin9
Syncrip
Myo1d
Specc1l
Fbln2
Atp1a1
Eprs
Ehd2
Hsd17b4
Myo1d
Irs1
Hnrnpu
Krt33a
Kbtbd5
Jup
Copb2
Hadha
Copb2
Gars
Eef1a1
Lmo7
Lmo7
IPI00230941
IPI00201578
IPI00201578
IPI00201578
IPI00208118
IPI00476704
IPI00230941
IPI00230941
IPI00391300
IPI00209113
IPI00201578
IPI00476704
IPI00209113
58223
53716
223846
223846
223846
60567
111364
53716
53716
233603
226326
223846
111364
226326
8
11
23
16.70%
LLVMLLAHGSK
R
E
58.1
22.9
2
9
27
9
26
16
13
29
9
32
19
27
29
9
60
32
18.80%
21.50%
13.30%
31.90%
35.10%
LLVMLLAHGSKEEVNETYGDGDGR
LLYNNVSNFGR
LMEALFPEGPER
LMHLSNLSR
LMLLLEVISGER
R
K
R
R
K
T
L
W
T
L
51
57
45.4
44.6
83.2
30.6
27.9
28.5
27.6
26
2
2
2
2
2
3
52
13
2
3
9
4
4
44
31
5
9
2
8
11
6
3
2
10
44
21
3
69
13
2
3
9
4
4
55
39
5
12
2
8
11
6
3
2
12
55
24
3
255
21
2
3
9
4
4
144
145
7
37
2
12
12
6
3
2
27
141
95
5.78%
53.00%
14.80%
2.55%
3.62%
7.99%
8.47%
6.79%
47.80%
31.80%
6.64%
23.80%
2.67%
12.30%
15.90%
10.90%
3.87%
4.18%
24.50%
38.90%
19.80%
LMMDPLTGLNR
LMYNSSNPVLK
LNALGFSLEQR
LNAYTGVVSLQR
LNIPVNQVNPR
LNLNNTVLSK
LNPFGNTFLNR
LNPQNAFFSGR
LNQPQPDFTK
LNSEAAAVVLQLMNIR
LNTLLQR
LNVEVDAAPTVDLNR
LNVLR
LNYGIPAIVK
LNYYVGGEIVTIAHLDR
LPAKPEVSSDEDIQYR
LPEAAFLAR
LPFAAAQIGNSFR
LPLQDVYK
LPPQLLSTSNR
LPSAEPHQASFSSAEPR
R
R
R
R
R
R
K
K
R
K
K
R
R
R
R
R
R
K
R
R
R
G
N
L
S
D
R
F
L
N
R
A
V
L
L
T
V
T
N
I
A
Q
54.5
61.7
54.2
51
38.7
37.5
51.5
43.7
56.2
101
29.9
89
28.8
45.8
44.4
47.6
63.5
45.2
55.9
74.8
87.1
28.8
28.4
27
26.2
24.5
25.1
27.7
28.5
28.5
25.8
25.4
27.8
25.9
23.1
27.1
29.7
26.9
26.2
25.8
25.2
30
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
6
29
38
2
6
33
51
2
8
50
155
4.44%
17.10%
36.00%
77.50%
LPSGYYDFSVR
LPVLLLGR
LQASLESEVNALAAK
LQDEIQNMK
K
K
K
R
V
S
L
E
55.2
50.6
111
44.6
28.6
12
27.5
27.7
2
2
2
2
29
68
60
76
12
30
27
28
46
119
47
18
119
39
78
66
92
14
33
34
40
52
194
50
18
194
105
99
306
323
22
42
107
261
210
3095
182
21
3095
67.20%
43.10%
39.10%
46.50%
21.80%
33.70%
60.90%
62.20%
33.80%
51.60%
31.50%
17.90%
51.60%
LQDEIQNMKEEMAR
LQDLVDK
LQDLVDKLQVK
LQDSEEQVEAVNAK
LQEALER
LQEAQEELAGLQQHWR
LQEEMLQR
LQEEMLQREEAESTLQSFR
LQELEGAVK
LQEMESAVK
LQGEVEDLMVDVER
LQHQLVSTEDALR
LQLEK
R
R
R
R
R
K
K
K
K
K
R
R
K
H
L
V
C
Q
A
E
Q
S
S
A
D
V
43.7
39.3
38.3
90.1
39.6
34.8
63.6
48.7
56.1
45.5
103
76.1
37.1
30.2
26.2
22.5
29.4
26.2
29.4
27.9
30.7
26.3
27.4
30.2
28
28.9
2
2
2
2
2
2
2
2
2
2
2
2
2
M5:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
M5:Oxidation(+15.99),M6:
Oxidation(+15.99)
M5:Oxidation(+15.99)
M4:Oxidation(+15.99)
M12:Oxidation(+15.99)
M3:Oxidation(+15.99)
M4:Oxidation(+15.99)
M8:Oxidation(+15.99)
M5:Oxidation(+15.99),M8:
Oxidation(+15.99)
M7:Oxidation(+15.99)
M4:Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
M7:Oxidation(+15.99)
M19:Oxidation(+15.99)
M5:Oxidation(+15.99)
M7:Oxidation(+15.99)
M4:Oxidation(+15.99)
M4:Oxidation(+15.99),M8:
Oxidation(+15.99)
M16:Oxidation(+15.99)
M4:Oxidation(+15.99),M7:
Oxidation(+15.99),M21:
Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
890.4067
658.3483
1,778.80
1,314.68
1,779.80
1,315.69
2
2
4.55
2.16
308
729
321
739
TRUE
TRUE
758.6939
622.3684
728.9044
538.3064
423.7383
681.6945
458.7595
479.7828
403.9815
1,147.58
919.9766
574.2966
614.3115
770.8765
689.361
2,273.06
1,242.72
1,455.79
1,611.90
845.461
2,042.06
915.5034
957.5499
1,611.89
1,146.57
1,837.94
1,146.58
1,839.91
1,539.74
1,376.71
2,274.06
1,243.73
1,456.80
1,612.90
846.4686
2,043.06
916.5105
958.5575
1,612.90
1,147.58
1,838.94
1,147.58
1,840.92
1,540.74
1,377.71
3
2
2
3
2
3
2
2
4
1
2
2
3
2
2
2.86
1.99
0.23
0.63
0.33
3.42
0.84
0.23
0.25
2.10
3.41
0.46
0.42
1.45
1.00
657
134
1845
1845
232
863
343
452
1873
50
50
50
50
1331
241
675
144
1856
1857
238
881
349
459
1885
59
65
59
65
1342
252
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
774.717
416.9035
617.8439
889.4691
932.9774
758.9047
679.8585
794.4101
2,321.13
1,247.69
1,233.67
1,776.92
1,863.94
1,515.79
1,357.70
2,380.21
2,322.13
1,248.70
1,234.68
1,777.93
1,864.94
1,516.80
1,358.72
2,381.21
3
3
2
2
2
2
2
3
1.33
0.26
0.33
2.49
1.26
0.19
5.54
1.81
1676
184
235
1996
617
746
632
608
1695
193
244
2012
634
758
644
629
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
408.2474
769.9429
758.8861
487.2517
466.7381
814.4792
1,537.87
1,515.76
972.4878
931.4606
815.488
1,538.88
1,516.77
973.4956
932.469
2
2
2
2
2
1.15
1.17
0.38
0.10
0.55
135
2374
387
407
403
141
2388
399
414
410
TRUE
TRUE
TRUE
TRUE
TRUE
794.8742
856.4634
626.988
615.3424
471.2813
796.9816
529.8145
1,007.03
722.1271
499.3073
795.4539
599.3516
3,175.47
1,710.91
1,877.94
1,228.67
940.547
1,591.95
1,057.61
2,012.04
2,884.48
996.599
1,588.89
1,196.69
3,176.50
1,711.92
1,878.94
1,229.67
941.5534
1,592.95
1,058.62
2,013.03
2,885.48
997.6048
1,589.89
1,197.70
4
2
3
2
2
2
2
2
4
2
2
2
7.33
1.73
3.27
2.12
1.53
1.33
0.08
5.90
0.48
2.06
3.86
0.17
584
503
510
17
780
499
322
525
525
786
855
38
610
516
525
27
789
513
331
542
549
794
868
47
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
477.3059
671.3676
643.8333
541.2885
443.2618
1,063.54
952.5962
1,340.72
1,285.65
1,080.56
884.5079
2,125.07
953.6038
1,341.73
1,286.66
1,081.57
885.516
2,126.07
2
2
2
2
2
2
0.23
0.48
0.54
0.71
0.30
5.24
101
150
23
349
667
79
109
161
34
357
673
97
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
561.3215
493.2879
568.2842
529.8145
800.9395
770.3972
769.4074
522.8015
423.7561
407.7428
421.7595
1,120.63
984.5602
1,134.55
1,057.61
1,599.86
1,538.78
1,536.80
1,043.59
845.4966
813.47
841.5034
1,121.63
985.5684
1,135.56
1,058.62
1,600.87
1,539.78
1,537.80
1,044.59
846.505
814.4787
842.51
2
2
2
2
2
2
2
2
2
2
2
2.86
0.40
1.11
0.04
0.79
1.53
1.30
0.85
0.60
1.08
1.49
812
471
336
765
155
460
480
529
237
753
420
821
478
345
773
169
471
491
538
244
759
426
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M4:Oxidation(+15.99)
599.3554
1,196.70
1,197.70
2
0.07
427
437
TRUE
M4:Oxidation(+15.99)
873.7626
648.8408
702.848
543.7907
694.8944
2,618.26
1,295.67
1,403.68
1,085.57
1,387.77
2,619.27
1,296.67
1,404.68
1,086.57
1,388.78
3
2
2
2
2
0.22
2.95
3.33
0.48
1.03
427
1216
761
653
65
450
1226
772
661
76
TRUE
TRUE
TRUE
TRUE
FALSE
646.822
641.3295
624.3416
660.8699
632.3663
558.3267
646.8414
625.8184
594.3066
879.486
429.2652
813.429
614.3991
544.33
645.0145
616.3117
494.2855
696.3787
488.2797
613.3496
905.9417
1,291.63
1,280.64
1,246.67
1,319.72
1,262.72
1,114.64
1,291.67
1,249.62
1,186.60
1,756.96
856.5148
1,624.84
613.3913
1,086.64
1,932.02
1,845.91
986.5554
1,390.74
974.5438
1,224.68
1,809.87
1,292.63
1,281.65
1,247.67
1,320.73
1,263.72
1,115.64
1,292.68
1,250.63
1,187.61
1,757.96
857.521
1,625.85
614.399
1,087.65
1,933.02
1,846.92
987.5628
1,391.74
975.5517
1,225.69
1,810.87
2
2
2
2
2
2
2
2
2
2
2
2
1
2
3
3
2
2
2
2
2
1.35
0.03
0.42
3.36
5.92
2.66
0.16
0.62
0.69
3.22
1.97
0.17
0.16
0.37
4.82
0.42
0.41
4.24
0.09
0.63
1.77
193
534
272
1127
648
426
125
718
985
192
526
209
591
478
543
661
751
369
248
1265
518
203
544
282
1138
658
435
135
728
994
207
532
223
595
487
559
676
759
381
255
1275
534
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
652.3217
440.8034
772.4213
M8:Oxidation(+15.99)
567.7769
M8:Oxidation(+15.99),M12:
Oxidation(+15.99)
883.9072
415.7365
433.5953
780.3815
429.7384
645.9937
M5:Oxidation(+15.99)
531.7667
M5:Oxidation(+15.99)
780.7122
493.7802
M4:Oxidation(+15.99)
525.7612
M9:Oxidation(+15.99)
824.3997
755.4053
630.3828
1,302.63
879.5912
1,542.83
1,133.54
1,303.63
880.5986
1,543.83
1,134.55
2
2
2
2
2.65
0.53
1.05
0.50
341
262
761
365
351
269
775
373
TRUE
TRUE
TRUE
TRUE
1,765.80
829.4573
1,297.76
1,558.75
857.4612
1,934.96
1,061.52
2,339.11
985.5448
1,049.51
1,646.78
1,508.80
629.375
1,766.81
830.4626
1,298.77
1,559.76
858.4686
1,935.97
1,062.53
2,340.11
986.5525
1,050.51
1,647.79
1,509.80
630.3828
2
2
3
2
2
3
2
3
2
2
2
2
1
0.71
2.99
1.16
0.05
0.54
1.18
0.04
2.89
0.22
0.38
0.99
0.11
0.06
365
1865
1865
1398
105
655
189
189
1838
1795
1422
952
962
378
1871
1875
1411
111
670
196
207
1846
1803
1435
964
966
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M3:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M13:Oxidation(+15.99)
IPI00391300,IPI00558912
IPI00197888
IPI00197888
IPI00230775
IPI00391300
IPI00197888,IPI00210945,IPI00230775
IPI00370090,IPI00421795,IPI00370073
IPI00200792,IPI00421785
IPI00207038
IPI00768956
IPI00382153,IPI00551558,IPI00393340
IPI00421812,IPI00551558,IPI00559533
IPI00213463
IPI00370090
IPI00370090
IPI00421795,IPI00551773
IPI00197888,IPI00210945,IPI00230775
IPI00195673,IPI00475639
IPI00197888,IPI00210945,IPI00230775
IPI00197888,IPI00187731,IPI00230775
IPI00765011,IPI00360356,IPI00189819
IPI00391300
IPI00197888,IPI00210945,IPI00230775
IPI00393340
IPI00197888
IPI00421795,IPI00370073,IPI00421855
IPI00200792,IPI00421785
IPI00475639
IPI00197888,IPI00210945,IPI00230775
IPI00197888
IPI00197888
IPI00230775
IPI00230775
IPI00370090
IPI00782724,IPI00778882,IPI00777201
IPI00213463
IPI00391300,IPI00400680,IPI00400681
Myh10
Myh10
Myh9
Myh10
Rrbp1
Myo1e
Myo1c
Myo1d
Myh9
Kpnb1
Dsp
234kDaprotein
234kDaprotein
Myosin9
234kDaprotein
similartoRibosomebindingprotein1
MyosinIe
MyosinIc
MyosinId
Myosin9
Importinsubunitbeta1
similartodesmoplakinisoformIisoform2
46
40
113
57
12
2
37
43
119
8
18
52
44
179
66
12
2
45
53
194
8
18
210
116
1862
435
15
2
110
221
3095
9
28
33.80%
29.60%
50.90%
39.20%
10.90%
3.52%
41.10%
48.10%
51.60%
13.20%
7.79%
LQNELDNVSTLLEEAEK
LQNELDNVSTLLEEAEKK
LQQELDDLLVDLDHQR
LQQELDDLTVDLDHQR
LQQENSILR
LQQIFIELTLK
LQQLFIELTLK
LQQLFIQLVLK
LQQLFNHTMFILEQEEYQR
LQQVLQMESHIQSTSDR
LQSLTENLTK
K
K
R
R
R
K
K
K
K
R
R
K
G
Q
Q
D
A
S
Q
E
I
E
123
28.9
117
109
35.1
65
66.3
64.6
90.4
23.7
34.4
29.6
28
29.2
30.2
26.8
19.3
19.2
11.8
30.3
30.1
26.6
2
2
2
2
2
2
2
2
2
2
2
Dnm2
Rrbp1
Myh3
Uso1
Myh9
IPI00391300
233603
IPI00391300
233603
IPI00209113
226326
IPI00391300
233603
IPI00188079
143655
IPI00207988,IPI00388110
126813
IPI00393867
119797
IPI00207989
116081
IPI00209113
226326
IPI00204261
97167
IPI00366081
332383
IPI00210319,IPI00389749,IPI00389750,I
PI00896218
98232
IPI00188079
143655
IPI00201578
223846
IPI00324618
107147
IPI00209113
226326
4
12
77
3
138
4
12
85
3
222
4
15
149
3
3511
5.28%
10.90%
47.90%
3.65%
55.70%
LQSQLLSLEK
LQSSEVEVK
LQTEAGELSR
LQTENSELQQR
LQVELDSVTGLLNQSDSK
K
K
R
R
K
E
S
Q
A
S
34.4
29.9
65.6
49.6
123
25.5
28.6
27.8
28.9
27.4
Rpn2
Ckap4
IPI00188059
IPI00365982
69060
63529
2
6
2
7
2
11
4.44%
18.40%
LQVSSVLSQPLAQAAVK
LQYVEDGVYSMQVASASHTESLESLLSK
R
R
L
S
89
68.8
20.5
30.2
IPI00554334
IPI00231407,IPI00231784
IPI00324618
IPI00421345
IPI00188079
IPI00209113
IPI00199325
IPI00393340
IPI00393340
IPI00382153
IPI00382153
IPI00421857
IPI00421857
IPI00391300
IPI00372146
IPI00372146
IPI00373505
IPI00373011
IPI00209938
IPI00213463
IPI00207989
IPI00454475
IPI00325146
IPI00373011
IPI00209113
IPI00209082,IPI00454431
IPI00204703
IPI00231407,IPI00231784
IPI00392930
IPI00339167
IPI00372700
IPI00568788,IPI00768137
81251
77453
107147
156634
143655
226326
51312
59233
59233
61809
61809
64814
64814
233603
105981
105981
39455
83779
78377
104900
116081
57238
38662
83779
226326
102946
46501
77453
257845
50134
103329
85638
27
6
3
46
12
132
7
9
9
18
22
10
10
70
29
26
6
5
20
22
42
2
8
5
111
22
3
7
32
12
6
5
33
7
3
58
12
196
8
12
11
24
29
13
13
82
35
32
7
5
26
23
51
2
11
5
172
26
3
8
43
15
6
5
100
15
3
181
15
883
10
55
63
456
634
264
264
145
51
60
8
6
63
34
135
3
13
6
2414
34
4
14
100
42
6
5
50.10%
14.60%
3.65%
39.90%
10.90%
55.20%
20.00%
24.50%
26.10%
28.30%
26.90%
16.20%
16.20%
45.50%
36.10%
31.90%
21.90%
7.95%
26.80%
33.50%
46.20%
11.40%
30.10%
7.95%
50.00%
41.70%
11.00%
15.80%
18.20%
36.40%
8.26%
7.64%
LRDTPDGTFLVR
LREDENAEPVGTTYQK
LREEIEELR
LREEWQR
LRGELESSDQVR
LRLEVNLQAMK
LRQPPVIVLQR
LRSEIDHVK
LRSEIDHVKK
LRSEIDNVK
LRSEIDNVKK
LRSEIDSVK
LRSEIDSVKK
LRVELAEK
LSDSTAGADSLLDVSSEADQQDLLVLLQAK
LSENAGIQSLLLSK
LSESELK
LSETSIKDR
LSFEEIER
LSGSNPYTSVTPQIINSK
LSITEVTK
LSLDVEIATYR
LSLEGDHSTPPSAYGSVKPYTNFDAER
LSLGTYASLHGR
LSLSTK
LSNRPAFMPSEGR
LSSLIILMPHHVEPLER
LSSPVLHR
LSTHELTSLLEK
LSVDYGKK
LSVEGFAVDK
LSVLQEEKR
R
R
R
K
K
K
K
R
R
R
R
R
R
R
R
K
K
R
R
K
K
K
K
K
K
R
K
R
R
R
K
K
D
T
S
A
E
A
G
K
Q
K
Q
K
Q
A
V
I
Q
M
Q
W
R
E
D
I
L
M
L
L
E
S
M
Q
48.6
92.4
34.8
33.9
49.8
59
36.2
38
40.2
47.9
50.1
37.4
39.7
26.3
67.5
97.4
32.2
38.2
59
78.1
43.2
89.3
31.9
31.6
42.8
49.2
35.7
38.8
50.1
35.9
33.7
26.3
27.6
30.1
27.1
28.4
28.1
25.9
13.4
25.8
22.6
26.9
26
27.5
24.7
26.2
29.2
24.7
27.2
27.6
27.2
28.3
24.6
27
30.7
28.2
21.6
29.2
24.5
23.7
26.3
25.2
27.9
26.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Isoform1ofDynamin2
similartoRibosomebindingprotein1
Myosin3
Generalvesiculartransportfactorp115
Myosin9
Dolichyldiphosphooligosaccharideprotein
glycosyltransferasesubunit2
cytoskeletonassociatedprotein4
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
Dbn1
IsoformAofDrebrin
Uso1
Generalvesiculartransportfactorp115
Lmo7
LMO7b
Rrbp1
similartoRibosomebindingprotein1
Myh9
Myosin9
Htra1
HtrAserinepeptidase1,isoformCRA_a
LOC683313
Keratin,typeIIcytoskeletal6A
LOC683313
Keratin,typeIIcytoskeletal6A
Krt5
Keratin,typeIIcytoskeletal5
Krt5
Keratin,typeIIcytoskeletal5
Krt1
Keratin,typeIIcytoskeletal1
Krt1
Keratin,typeIIcytoskeletal1
Myh10
234kDaprotein
Rai14
Isoform2ofAnkycorbin
Rai14
Isoform2ofAnkycorbin
Tmod3
Tropomodulin3
Lima1
similartoEpithelialproteinlostinneoplasm
Nexn
Isoform1ofNexilin
Actn4
Alphaactinin4
Myo1d
MyosinId
Krt77
Keratin,typeIIcytoskeletal1b
Anxa2
IsoformShortofAnnexinA2
Lima1
similartoEpithelialproteinlostinneoplasm
Myh9
Myosin9
Actn1
Alphaactinin1
Serpinh1
SerpinH1
Dbn1
IsoformAofDrebrin
Mprip
258kDaprotein
Tuba1b
Tubulinalpha1Bchain
Npepps
aminopeptidasepuromycinsensitive
RGD1563532 86kDaprotein
972.9929
691.6974
975.5018
969.4829
550.8088
673.4103
673.4114
671.9285
1,242.10
672.6681
573.8225
1,943.97
2,072.07
1,948.99
1,936.95
1,099.60
1,344.81
1,344.81
1,341.84
2,482.19
2,014.98
1,145.63
1,944.98
2,073.07
1,949.99
1,937.96
1,100.61
1,345.81
1,345.81
1,342.85
2,483.20
2,015.98
1,146.64
2
3
2
2
2
2
2
2
2
3
2
0.65
2.20
1.21
0.46
3.03
2.30
3.93
2.03
3.08
3.29
0.03
1322
1322
1419
1462
722
412
426
407
476
558
1713
1338
1339
1434
1477
730
422
436
417
494
574
1722
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
2
2
2
579.8424
509.7767
552.2886
673.3414
973.5111
1,157.67
1,017.54
1,102.56
1,344.67
1,945.01
1,158.67
1,018.54
1,103.57
1,345.67
1,946.01
2
2
2
2
2
2.88
3.51
0.30
2.84
3.16
300
846
1281
811
1278
309
854
1290
821
1295
TRUE
TRUE
TRUE
TRUE
TRUE
2
2
870.0078
1,029.84
1,738.00
3,086.50
1,739.01
3,087.48
2
3
0.51
8.51
290
393
306
420
TRUE
TRUE
695.3789
925.4515
593.8267
508.7676
694.8624
665.8818
440.2822
548.8093
612.8579
537.3016
601.3489
523.7963
587.8444
479.2916
1,034.86
736.9207
403.2192
524.7864
511.7622
953.5017
445.764
640.3496
980.1381
637.8466
648.3936
739.3654
667.3746
454.7694
685.8807
455.2564
532.7866
551.3173
1,388.74
1,848.89
1,185.64
1,015.52
1,387.71
1,329.75
1,317.82
1,095.60
1,223.70
1,072.59
1,200.68
1,045.58
1,173.67
956.5676
3,101.56
1,471.83
804.4228
1,047.56
1,021.51
1,904.99
889.5124
1,278.68
2,937.39
1,273.68
647.3858
1,476.72
1,999.10
907.5232
1,369.75
908.4971
1,063.56
1,100.62
1,389.75
1,849.89
1,186.64
1,016.53
1,388.71
1,330.75
1,318.83
1,096.61
1,224.71
1,073.60
1,201.69
1,046.58
1,174.68
957.5734
3,102.57
1,472.83
805.4307
1,048.56
1,022.52
1,905.99
890.52
1,279.69
2,938.39
1,274.69
648.3933
1,477.72
2,000.10
908.5317
1,370.75
909.5046
1,064.56
1,101.63
2
2
2
2
2
2
3
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
3
2
1
2
3
2
2
2
2
2
0.55
1.01
1.99
0.32
2.49
3.06
1.18
0.74
1.13
0.19
0.48
0.15
1.18
2.08
0.92
0.69
0.10
1.08
0.69
1.81
0.32
1.17
4.29
0.26
0.53
0.44
3.93
0.70
0.29
0.31
2.21
0.08
338
150
735
949
1105
1557
142
380
380
392
392
407
407
1311
297
227
24
262
292
605
552
460
11
422
1325
347
263
140
638
157
855
180
349
165
743
955
1116
1567
152
388
389
400
401
415
416
1318
326
240
30
270
299
622
559
470
37
433
1330
359
279
147
649
164
864
188
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Tnnt3
Isoform1ofTroponinT,fastskeletalmuscle
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
12
16
46
Myh9
Myosin9
IPI00209113
226326
138
222
3511
55.70%
LTEMETMQSQLMAEK
R
L
82
30
2
Myh9
Myosin9
IPI00209113
226326
132
196
883
55.20%
LTEMETMQSQLMAEK
R
L
75.7
30.2
2
Myh3
Myosin3
IPI00201578
LOC682005;G
apdh;LOC685
186
Glyceraldehyde3phosphatedehydrogenase
IPI00555252,IPI00567177
Cand1
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
Cnn3
Calponin3
IPI00205566,IPI00782000
neuralprecursorcellexpressed,developmentallydown
Nedd4
regulatedgene4
IPI00876592
Hspa5
78kDaglucoseregulatedprotein
IPI00206624
Lmo7
LMO7b
IPI00421345
Lmo7
LMO7b
IPI00421345
Tubb6
Tubulin,beta6
IPI00195673
Copb1
Coatomersubunitbeta
IPI00211812
Copa
Copaprotein
IPI00372458
Tpm1
tropomyosin1,alphaisoformc
IPI00210945
Tpm1
tropomyosin1,alphaisoformc
IPI00210945
Tpm2
Isoform2ofTropomyosinbetachain
IPI00187731
LOC682005;G
apdh;LOC685
186
Glyceraldehyde3phosphatedehydrogenase
IPI00555252,IPI00567177
Myh14
myosin,heavychain14
IPI00367479
Atp5b
ATPsynthasesubunitbeta,mitochondrial
IPI00551812
Sdpr
Serumdeprivationresponseprotein
IPI00362416
Luzp1
leucinezipperprotein1
IPI00324444
Vcl
Vinculin
IPI00365286
Phosphatidylinositol3kinase,regulatorysubunit,
Pik3r2
polypeptide2,isoformCRA_a
IPI00554334
Myh10
234kDaprotein
IPI00391300
Jup
Junctionplakoglobin
IPI00421429
Tmpo
75kDaprotein
IPI00569391
Actn4
Alphaactinin4
IPI00213463
Actn1
Alphaactinin1
IPI00209082,IPI00454431
Copb1
Coatomersubunitbeta
IPI00211812
Myh3
Myosin3
IPI00201578
Pygb
Phosphorylase
IPI00357945
Krt35
TypeIhairkeratinKA30
IPI00421797
Myh9
Myosin9
IPI00209113
Myh3
Myosin3
IPI00201578
Ppp1r12a
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
Ppp1r12b
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
Serpinh1
SerpinH1
IPI00204703
Hspa5
78kDaglucoseregulatedprotein
IPI00206624
Iars
isoleucyltRNAsynthetase
IPI00365783
Kif5b
Kinesin1heavychain
IPI00364904
Scin
Kbtbd10
Kbtbd10
Hspa9
Vim
Dbn1
Actn4
Tubb6
Tubb5
Eef1a1
Emilin1
Myh10
Myh3
Clip2
Tpm1
Krt1
Scinderin
KelchrepeatandBTBdomaincontainingprotein10
KelchrepeatandBTBdomaincontainingprotein10
Stress70protein,mitochondrial
Vimentin
IsoformAofDrebrin
Alphaactinin4
Tubulin,beta6
Isoform1ofTubulinbeta5chain
Elongationfactor1alpha1
elastinmicrofibrilinterfacer1
234kDaprotein
Myosin3
111kDaprotein
tropomyosin1,alphaisoformc
Keratin,typeIIcytoskeletal1
86
104
217
50.30%
LTGAVMHYGNMK
K
F
44.7
29.2
2
8
12
2
9
12
3
16
12
3
27.90%
12.40%
11.80%
LTGMAFR
LTLIDPETLLPR
LTLQPVDNSTISLQMGTNK
K
K
K
V
L
V
34.2
31.5
65.3
29.1
21
28.5
2
2
2
M15:Oxidation(+15.99)
102739
72331
156634
156634
50041
106996
138346
32831
32831
32941
11
17
16
44
6
14
15
27
28
4
11
19
19
53
6
14
15
41
47
7
12
42
42
78
10
15
21
231
149
21
19.00%
29.70%
16.10%
37.80%
33.10%
20.80%
13.60%
50.70%
52.50%
53.20%
LTMYGNPATSQPVTSSNHSSR
LTPEEIER
LTSVVTAR
LTSVVTARPFGTSSR
LTTPTYGDLNHLVSATMSGVTTSLR
LVEKPSPLTLAPHDFANIK
LVGQSIIAYLQK
LVIIESDLER
LVIIESDLERAEER
LVILEGELER
R
R
R
R
K
K
K
K
K
K
G
M
P
G
F
A
K
A
A
S
49.3
44.6
57.1
37.5
65.3
29
54.6
72.5
36.4
67.8
30.9
27.3
25.1
25.8
28.5
22.5
20.4
26.4
27.7
25.1
2
2
2
2
2
2
2
2
2
2
35810
229088
56336
46368
119795
116599
8
2
5
5
3
17
9
2
6
6
3
18
16
19
8
12
3
25
27.90%
4.25%
14.00%
14.60%
3.17%
20.40%
LVINGKPITIFQER
LVLDQLR
LVLEVAQHLGESTVR
LVNMLDAVR
LVNTTITPEPEPK
LVQAAQMLQSDPYSVPAR
K
R
R
K
K
K
D
C
T
E
L
D
43.9
44.9
56.7
51.4
39
61
21
24.6
24.7
28
26.7
29.1
2
2
2
2
2
2
81251
233603
81784
74885
104900
102946
106996
223846
96759
50657
226326
223846
115268
111371
46501
72331
144271
109514
27
70
9
2
22
16
14
69
6
4
123
47
9
5
3
21
2
13
33
82
9
2
24
19
14
76
6
5
194
50
9
5
4
27
2
13
100
145
15
2
38
32
15
172
6
10
2027
182
16
6
4
59
2
13
50.10%
45.50%
14.10%
4.05%
32.30%
35.10%
20.80%
42.20%
8.51%
12.30%
52.30%
31.50%
10.90%
8.86%
11.00%
39.60%
1.51%
17.30%
LVQEHVDEQDTAPPALPPKPSK
LVQEQGSHSK
LVQLLVK
LVSAAASPSLIR
LVSIGAEEIVDGNAK
LVSIGAEEIVDGNVK
LVTEMGTYATQSALSSSR
LVTLVQEK
LVTSIGDVVNHDPVVGDR
LVVQIDNAK
LVWVPSTK
LYDQHLGK
LYEQILAENEK
LYESALTENQK
LYGPSSVSFADDFVR
LYGSGGPPPTGEEDTSEKDEL
LYLINSPVVR
LYLVDLAGSEK
R
K
R
R
K
K
K
K
K
R
K
K
K
K
R
K
R
K
V
F
A
E
M
M
P
N
L
L
N
S
L
L
S
A
V
49
48.4
38
52.8
95.7
99.7
111
52.4
40.8
51.3
35.5
34.7
63.7
59.3
80.1
81.1
25.3
50.7
28.4
26.9
15.1
25.1
26.8
26.5
29.9
24.4
28
23.2
27.2
28
28.6
29.1
30.2
30.5
22.8
27.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
6
8
8
13
24
8
16
5
15
8
11
49
55
28
35
10
6
11
11
13
29
9
18
5
16
9
11
53
62
31
57
13
8
19
19
23
137
21
21
12
69
15
11
157
146
43
309
264
11.30%
18.20%
18.20%
28.00%
51.90%
18.70%
24.30%
30.20%
37.60%
20.80%
15.40%
33.40%
37.80%
34.30%
70.80%
16.20%
LYMVSDASGSMK
LYQSTLLQDGLK
LYQSTLLQDGLKDLLEEK
LYSPSQIGAFVLMK
MALDIEIATYR
MAPTPIPTR
MAPYQGPDAAPGALDYK
MASTFIGNSTAIQELFK
MAVTFIGNSTAIQELFK
MDSTEPPYSQK
MDTQEETAAELSLR
MEEEVLLLEDQNSK
MEGDLNEIEIQLSHANR
MEHQLELGNLQAK
MEIQEIQLK
MEISELNR
K
R
R
K
K
R
R
K
K
K
R
K
K
K
K
K
V
D
K
M
K
S
S
R
R
R
L
F
Q
H
E
V
71.5
77.9
72
58.7
66.4
38
79.1
111
97.9
31.8
102
126
66.1
40.2
53.4
53.3
28.3
25.5
25.5
27.6
28.6
26.6
29.5
29.4
28.3
27.7
29.4
29.9
30.1
28.8
28.4
26.7
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
13
24
76
33.90%
MEKDLNELQTLIEAHFENR
R
K
73.4
29.9
2
5
4
19
6
4
20
13
4
38
71.80%
5.15%
17.70%
MELQEMQLK
MEPLNNLQVAVK
MESAELDVPIQSIFTR
K
K
K
E
N
D
46.1
29.8
78.8
27.4
28
29.2
2
2
2
Isoform2ofTroponinT,cardiacmuscle
Isoform2ofTropomyosinbetachain
Isoform2ofAP2complexsubunitbeta1
Thrombospondin1
IPI00187731
32941
IPI00231502,IPI00389753,IPI00781916 105677
IPI00422076
129653
I
32.1
20.6
2
Krt5
Vim
Vim
Keratin,typeIIcytoskeletal5
Vimentin
Vimentin
IPI00382153
IPI00230941
IPI00230941
61809
53716
53716
20
38
38
26
51
51
628
155
155
28.80%
77.50%
77.50%
MFFDAELSQMQTHVSDTSVVLSMDNNR
MFGGSGTSSR
MFGGSGTSSRPSSNR
K
R
R
S
P
S
52.5
41.8
26
31.7
27.1
29.5
2
2
2
Hnrpm
Hadha
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
77613
82649
5
9
5
9
6
9
9.60%
16.40%
MGAGMGFGLER
MGLVDQLVDPLGPGIK
R
K
M
S
81.8
70.8
27.2
26
2
2
Hnrpm
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
77613
9
9
11
16.70%
MGPAMGPALGAGIER
Hnrpm
Lmod3
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
similartoleiomodin3
IPI00568699
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
77613
57499
5
7
5
7
6
14
9.60%
17.00%
MGPLGLDHMASSIER
MGYHFELPGPR
R
K
M
M
36.9
25
30
28.2
2
2
Pik3r1
83516
10
11
19
17.10%
MHGDYTLTLR
K
K
36.8
28.2
2
Rai14
Isoform2ofAnkycorbin
IPI00372146
105981
26
32
60
31.90%
MHLLYAVQGQMDEDVQK
R
V
75.8
30.7
2
Eif3c
Hspa8
Hspa5
Clip2
Myh3
Actn1
Actn4
Eukaryotictranslationinitiationfactor3subunitC
Heatshockcognate71kDaprotein
78kDaglucoseregulatedprotein
111kDaprotein
Myosin3
Alphaactinin1
Alphaactinin4
IPI00914189
IPI00208205
IPI00206624
IPI00476704
IPI00201578
IPI00209082,IPI00454431
IPI00213463
105420
70855
72331
111364
223846
102946
104900
6
18
19
19
86
13
28
6
24
20
20
104
17
34
6
59
36
31
217
28
49
8.89%
39.00%
33.90%
21.40%
50.30%
30.80%
39.60%
MIINEELMASLDQPTQTVVMHR
MKEIAEAYLGK
MKETAEAYLGK
MKETVEGLQDK
MKGTLEDQIISANPLLEAFGNAK
MLDAEDIVGTARPDEK
MLDAEDIVNTARPDEK
K
K
K
R
K
K
K
T
T
K
L
T
A
A
34.7
59.5
58.4
44.2
84.2
72.4
75.4
30.4
27.8
28.2
28.8
28.3
29.8
30.4
2
2
2
2
2
2
2
Ddx5
Smtn
Ddx5
smoothelin
IPI00464718
IPI00361871,IPI00561311
69223
99862
3
9
3
9
8
12
6.83%
11.60%
MLDMGFEPQIR
MLDQATNFEER
R
K
K
K
47
74.7
29.1
28
2
2
Clip2
Lmod3
Tmod3
Cand1
111364
57499
39455
136349
18
8
8
12
18
8
10
12
21
14
18
12
17.90%
22.00%
34.70%
12.40%
MLDYEMLQR
MLEDERVPVSFVQSEENTQK
MLEENTNILK
MLTGPVYSQSTALTHK
K
R
K
R
A
Q
L
Q
43.9
66.2
34.1
26.3
28.1
30.8
28.9
29.4
2
2
2
2
Nedd4
Myh9
Lmna
111kDaprotein
IPI00476704
similartoleiomodin3
IPI00568699
Tropomodulin3
IPI00373505
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
234kDaprotein
IPI00391300
Rhoguaninenucleotideexchangefactor2
IPI00368617
similartoleiomodin3
IPI00568699
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
Caldesmon
IPI00208118
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
IPI00876592
Myosin9
IPI00209113
LaminA
IPI00201060
102739
226326
74307
11
138
2
11
222
2
Cnn3
Flot1
Vcl
Tubb2a
Atp1a1
Myo1c
Nes
Calponin3
IPI00205566,IPI00782000
Isoform1ofFlotillin1
IPI00208784
Vinculin
IPI00365286
Tubulinbeta2Achain
IPI00475639
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
MyosinIc
IPI00393867
Isoform1ofNestin
IPI00194103
36418
47481
116599
49889
113040
119797
208776
2
6
17
4
9
50
16
3
6
18
4
9
72
17
Tubb5
Isoform1ofTubulinbeta5chain
IPI00197579
49653
15
16
Lmod2
Krt42
Krt42
Npm1
Vcl
Leiomodin2
Keratin,typeIcytoskeletal42
Keratin,typeIcytoskeletal42
IsoformB23.1ofNucleophosmin
Vinculin
IPI00372026
IPI00421791
IPI00421791
IPI00197553,IPI00230893,IPI00778173
IPI00365286
61700
50196
50196
32542
116599
3
2
2
2
17
Hadha
Hspa8
Gsn
Lmod3
Flii
Myh9
Myh3
Thbs1
Hspa9
Myh3
Myh3
Ncl
Jup
Hspa5
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Heatshockcognate71kDaprotein
IPI00208205
70855
Isoform2ofGelsolin
IPI00923716
80911
similartoleiomodin3
IPI00568699
57499
FlightlessIhomolog
IPI00211698
144843
Myosin9
IPI00209113
226326
Myosin3
IPI00201578
223846
Thrombospondin1
IPI00422076
129653
Stress70protein,mitochondrial
IPI00363265
73840
Myosin3
IPI00201578
223846
Myosin3
IPI00201578
223846
Nucleolin
IPI00231827,IPI00882501
77259
Junctionplakoglobin
IPI00421429
81784
78kDaglucoseregulatedprotein
IPI00206624
72331
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
83516
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
MyosinIc
IPI00393867
119797
MyosinIc
IPI00393867
119797
SP120
IPI00210090,IPI00566967
87731
Alphaactinin4
IPI00213463
104900
Caldesmon
IPI00208118
60567
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
MyosinIc
IPI00393867
119797
TypeIkeratinKA16
IPI00421793
50760
Keratin,typeIcytoskeletal42
IPI00421791
50196
Isoform2ofDihydropyrimidinaserelatedprotein3 IPI00203250
73882
234kDaprotein
IPI00391300
233603
Dolichyldiphosphooligosaccharideprotein
glycosyltransferasesubunit2
IPI00188059
69060
Myosin3
IPI00201578
223846
MyosinId
IPI00207989
116081
MyosinId
IPI00207989
116081
Calnexin
IPI00199636
67239
Myosin9
IPI00209113
226326
Insulinreceptorsubstrate1
IPI00199662
131160
234kDaprotein
IPI00391300
233603
Keratin,typeIIcytoskeletal5
IPI00382153
61809
Keratin,typeIIcytoskeletal5
IPI00382153
61809
IPI00557424,IPI00764064,IPI00776515,I
70kDaprotein
PI00782066
69603
Tubulinalpha1Bchain
IPI00339167
50134
Keratin,typeIIcytoskeletal73
IPI00421780
60370
similartoKeratin,typeIIcytoskeletal6G
IPI00768956
57419
Myosin3
IPI00201578
223846
Dihydropyrimidinaserelatedprotein2
IPI00870112
62260
Insulinreceptorsubstrate1
IPI00199662
131160
Clathrinheavychain1
IPI00193983
191585
Isoform1ofEndoplasmin
IPI00365985
92756
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Myosin9
IPI00209113
226326
234kDaprotein
IPI00391300
233603
Vimentin
IPI00230941
53716
Clathrinheavychain1
IPI00193983
191585
Copaprotein
IPI00372458
138346
Myosin3
IPI00201578
223846
Myosin9
IPI00209113
226326
234kDaprotein
IPI00391300
233603
Elongationfactor2
IPI00203214
95268
similartocoronin,actinbindingprotein,2B
IPI00373332
54948
Isoform1ofNexilin
IPI00209938
78377
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
MyosinIc
IPI00393867
119797
Leiomodin2
IPI00372026
61700
Tropomodulin1
IPI00189723,IPI00421889
40464
Clathrinheavychain1
IPI00193983
191585
Clathrinheavychain1
IPI00193983
191585
Rhoguaninenucleotideexchangefactor2
IPI00368617
111895
Coatomersubunitbeta'
IPI00231953
102535
Isoform1ofProteintransportproteinSec31A
IPI00210147,IPI00515833
135256
HeatshockproteinHSP90alpha
IPI00210566
84800
HeatshockproteinHSP90beta
IPI00471584
83266
methioninetRNAsynthetase
IPI00366397
101566
Vinculin
IPI00365286
116599
MyosinIc
IPI00393867
119797
LMO7b
IPI00421345
156634
78kDaglucoseregulatedprotein
IPI00206624
72331
Heatshockcognate71kDaprotein
IPI00208205
70855
Myosin9
IPI00209113
226326
similartoleiomodin3
IPI00568699
57499
Leucinerichrepeatflightlessinteractingprotein2
IPI00373564,IPI00780550
49756
Collagenalpha2(I)chain
IPI00188921
129547
Heatshockcognate71kDaprotein
IPI00208205
70855
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
MyosinId
IPI00207989
116081
Isoform1ofTubulinbeta5chain
IPI00197579
49653
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
234kDaprotein
IPI00391300
233603
Isoform1ofFibronectin
IPI00200757,IPI00231982,IPI00231983 272486
smoothelin
IPI00361871,IPI00561311
99862
Isoform2ofPhosphatidylinositolbindingclathrinassembly IPI00194958,IPI00194959,IPI00471607,I
protein
PI00565441
64640
234kDaprotein
IPI00391300
233603
Isoform1ofNexilin
IPI00209938
78377
MyosinIc
IPI00393867
119797
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
Coatomersubunitbeta
IPI00211812
106996
Myosin9
IPI00209113
226326
Isoform2ofGelsolin
IPI00923716
80911
MyosinId
IPI00207989
116081
258kDaprotein
IPI00392930
257845
Alphaactinin1
IPI00209082,IPI00454431
102946
Pik3r1
Pik3r2
Pik3ca
Myh10
Arhgef2
Lmod3
Hadha
Cald1
Pik3r1
Pik3r2
Myo1c
Myo1c
Hnrnpu
Actn4
Cald1
Pik3ca
Myh9
Myh9
Myh9
Myo1c
Krt16
Krt42
Dpysl3
Myh10
Rpn2
Myh3
Myo1d
Myo1d
Canx
Myh9
Irs1
Myh10
Krt5
Krt5
Syncrip
Tuba1b
Krt73
LOC683613
Myh3
Dpysl2
Irs1
Cltc
Tra1
Hadha
Myh9
Myh10
Vim
Cltc
Copa
Myh3
Myh9
Myh10
Eef2
Coro2b
Nexn
Atp1a1
Myo1c
Lmod2
Tmod1
Cltc
Cltc
Arhgef2
Copb2
Sec31a
Hsp90aa1
Hsp90ab1
Mars
Vcl
Myo1c
Lmo7
Hspa5
Hspa8
Myh9
Lmod3
Lrrfip2
Col1a2
Hspa8
Myh10
Myh10
Myo1d
Tubb5
Myh9
Myh9
Myh10
Fn1
Smtn
Picalm
Myh10
Nexn
Myo1c
Atp5a1
Copb1
Myh9
Gsn
Myo1d
Mprip
Actn1
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
35810
136349
36418
Tnnt2
K
M10:Oxidation(+15.99)
223846
Tpm2
Ap2b1
Thbs1
LTAPK
M11:Oxidation(+15.99)
529.3353
M4:Oxidation(+15.99),M7:
Oxidation(+15.99),M12:
Oxidation(+15.99)
909.4025
M7:Oxidation(+15.99),M12:
Oxidation(+15.99)
901.4088
M6:Oxidation(+15.99),M11:
Oxidation(+15.99)
677.319
IPI00365568,IPI00391226
80184
IPI00190417
68198
IPI00190417
68198
IPI00363265
73840
IPI00230941
53716
IPI00231407,IPI00231784
77453
IPI00213463
104900
IPI00195673
50041
IPI00197579
49653
IPI00195372,IPI00551729
50096
IPI00199867
107542
IPI00391300
233603
IPI00201578
223846
IPI00476704
111364
IPI00210945
32831
IPI00421857
64814
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
34.40%
M9:Oxidation(+15.99)
M7:Oxidation(+15.99)
R
M
64.6
29.2
2
528.3274
529.3351
1
0.30
44
48
TRUE
1,816.79
1,817.80
2
0.05
868
882
TRUE
1,800.80
1,801.80
2
4.09
868
882
TRUE
1,352.62
1,353.63
2
0.57
353
364
TRUE
406.2106
690.9111
1,038.54
810.4056
1,379.81
2,075.07
811.4137
1,380.81
2,076.07
2
2
2
0.33
2.77
4.90
226
958
233
232
969
251
TRUE
TRUE
TRUE
751.0207
493.7622
423.7568
789.9371
884.456
697.3955
666.9011
593.8383
836.4511
585.842
2,250.04
985.5087
845.498
1,577.86
2,650.34
2,089.16
1,331.79
1,185.66
1,670.89
1,169.67
2,251.04
986.516
846.5048
1,578.86
2,651.33
2,090.17
1,332.79
1,186.67
1,671.89
1,170.67
3
2
2
2
3
3
2
2
2
2
2.35
0.53
1.20
3.89
6.60
2.65
3.78
0.34
1.48
2.33
362
533
601
601
217
768
620
169
169
169
382
540
608
615
241
786
631
178
182
178
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
543.3237
428.7669
825.9648
523.7869
719.8948
664.009
1,626.95
855.5182
1,649.91
1,045.56
1,437.77
1,989.00
1,627.95
856.5258
1,650.92
1,046.57
1,438.78
1,990.01
3
2
2
2
2
3
1.15
0.26
2.39
0.90
1.55
2.35
65
716
95
65
674
88
78
722
109
73
686
105
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
799.4206
556.7907
406.7847
592.8543
757.908
771.9235
959.4691
465.2875
631.3357
500.2961
465.2771
487.2597
675.3521
648.3281
830.4092
1,089.49
587.3557
604.3347
2,395.24
1,111.57
811.5538
1,183.69
1,513.80
1,541.83
1,916.92
928.5593
1,890.98
998.5766
928.5386
972.5038
1,348.69
1,294.64
1,658.80
2,176.97
1,172.70
1,206.65
2,396.25
1,112.57
812.5611
1,184.70
1,514.81
1,542.84
1,917.92
929.5673
1,891.99
999.5839
929.5461
973.5109
1,349.70
1,295.65
1,659.80
2,177.97
1,173.70
1,207.66
3
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
0.34
3.22
0.65
0.44
0.99
0.82
4.03
0.29
1.83
0.53
0.37
0.73
0.75
0.12
5.39
0.07
3.36
3.27
281
590
527
302
126
107
514
878
623
168
31
553
937
880
133
634
625
227
302
599
533
313
140
121
531
885
640
176
38
560
947
890
147
654
634
237
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M3:Oxidation(+15.99),M11:
Oxidation(+15.99)
660.794
689.8842
1,053.57
M13:Oxidation(+15.99)
785.4241
M1:Oxidation(+15.99)
656.3375
M1:Oxidation(+15.99)
500.269
M1:Oxidation(+15.99)
890.9166
M1:Oxidation(+15.99)
937.476
M1:Oxidation(+15.99)
943.4932
M1:Oxidation(+15.99)
649.7841
M1:Oxidation(+15.99)
805.3753
M1:Oxidation(+15.99)
846.9058
M1:Oxidation(+15.99)
662.3193
M1:Oxidation(+15.99)
509.593
M1:Oxidation(+15.99)
574.3059
M1:Oxidation(+15.99)
504.2456
1,319.57
1,377.75
2,105.13
1,568.83
1,310.66
998.5224
1,779.82
1,872.94
1,884.97
1,297.55
1,608.73
1,691.80
1,983.93
1,525.76
1,146.60
1,006.48
1,320.58
1,378.76
2,106.13
1,569.84
1,311.66
999.5299
1,780.82
1,873.94
1,885.97
1,298.56
1,609.74
1,692.80
1,984.94
1,526.76
1,147.60
1,007.48
2
2
2
2
2
2
2
2
2
2
2
2
3
3
2
2
0.90
1.62
2.51
3.45
3.94
0.34
2.01
3.80
2.80
2.19
2.83
1.97
1.25
0.22
0.35
0.16
251
13
13
160
391
374
883
363
363
155
547
1020
1619
624
141
395
262
24
30
173
401
382
899
379
379
165
560
1033
1635
636
149
402
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M4:Oxidation(+15.99)
M3:Oxidation(+15.99)
M17:Oxidation(+15.99)
M4:Oxidation(+15.99)
M7:Oxidation(+15.99)
M5:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M6:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M10:
Oxidation(+15.99),M23:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M5:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M5:
Oxidation(+15.99)
M1:Oxidation(+15.99),M9:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M11:
Oxidation(+15.99)
M1:Oxidation(+15.99),M8:
Oxidation(+15.99),M20:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M4:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M6:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M9:
Oxidation(+15.99)
M1:Oxidation(+15.99),M5:
Oxidation(+15.99),M7:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
782.72
2,345.14
2,346.14
3
1.84
97
115
TRUE
591.2813
686.372
926.4663
1,180.55
1,370.73
1,850.92
1,181.55
1,371.73
1,851.92
2
2
2
0.03
4.12
4.50
141
811
174
149
822
189
FALSE
TRUE
TRUE
1,050.80
501.7195
515.2363
3,149.38
1,001.42
1,542.69
3,150.38
1,002.43
1,543.69
3
2
3
2.22
0.15
0.82
301
14
14
327
23
28
TRUE
TRUE
TRUE
579.2579
834.4573
1,156.50
1,666.90
1,157.51
1,667.90
2
2
0.39
1.34
485
215
495
230
TRUE
TRUE
TRUE
591
605
549.2617
440.5455
1,644.76
1,318.61
1,645.77
1,319.62
3
3
0.99
0.06
456
313
470
323
611.799
730.3563
1,221.58
1,222.59
2
0.83
364
373
TRUE
1,018.98
2,035.94
2,036.94
2
1.46
917
933
TRUE
868.7604
634.8323
628.8143
647.322
826.0979
888.4309
916.939
2,603.26
1,267.65
1,255.61
1,292.63
2,475.27
1,774.85
1,831.86
2,604.25
1,268.66
1,256.62
1,293.64
2,476.28
1,775.85
1,832.87
3
2
2
2
3
2
2
7.00
0.61
0.90
0.07
0.85
2.91
0.05
823
127
153
787
213
221
240
844
137
163
797
235
236
255
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
684.8185
685.306
1,367.62
1,368.60
1,368.63
1,369.61
2
2
0.06
1.22
253
596
263
606
FALSE
TRUE
615.7788
794.3828
610.814
583.9675
1,229.54
2,380.13
1,219.61
1,748.88
1,230.55
2,381.13
1,220.62
1,749.88
2
3
2
3
0.17
1.50
0.43
1.35
729
84
308
778
737
103
317
793
TRUE
TRUE
TRUE
TRUE
3
0.31
563
574
TRUE
0.61
3
4
4
4.70%
MNSIKPDLIQLR
R
K
48.8
27.1
2
27
33
100
50.10%
MNSLKPDLMQLR
R
K
35.4
28.5
2
15
49
9
10
3
15
17
53
9
10
3
18
28
157
9
16
3
41
18.40%
33.40%
13.30%
25.80%
5.24%
33.00%
MPNLMLMAK
MQAHIQDLEEQLDEEEGAR
MQDIPEETESR
MQEFFQPSPGR
MQLLEIITTDK
MQNNSAENETAEGEEKGESR
R
K
R
R
K
R
E
Q
D
S
T
S
35.5
68.2
32.1
57.2
55.9
63.3
28.7
31.2
28.4
28.5
27.1
29.2
2
2
2
2
2
2
12
3511
3
19.00%
55.70%
4.21%
MQNVAITGPAVPYSR
MQQNIQELEEQLEEEESAR
MQQQLDEYQELLDIK
R
K
R
D
Q
L
78.2
150
85.2
28.9
31
30
2
2
2
3
8
25
8
11
328
27
11.80%
16.60%
20.40%
33.70%
12.10%
48.80%
10.50%
MQTDKPFDQTTISLQMGTNK
MRGEAEAFAVGAR
MSAEINEIIR
MSATFIGNSTAIQELFK
MSINAEDVVVGDLVEVK
MSLLQLVEILR
MSLSLEVATYR
K
R
K
K
K
K
K
G
A
V
R
G
S
T
49.2
46
66.4
111
83.9
80.4
60.2
30.8
29
28.4
29.4
28.6
22.6
28.7
2
2
2
2
2
2
2
69
37.60%
MSMKEVDEQMLNVQNK
R
N
33.6
30.3
2
3
3
3
3
18
4
19
22
4
25
5.46%
25.90%
21.20%
13.70%
20.40%
MSMTSILTR
MSVEADINGLR
MSVEADINGLRR
MSVQPTVSLGGFEITPPVVLR
MTGLVDEAIDTK
R
R
R
K
K
N
R
V
L
S
62.3
78.3
33.7
73.2
54.2
28.5
28.3
28.6
24.9
29.1
2
2
2
2
2
9
18
28
9
8
138
66
19
13
66
47
2
6
19
9
23
41
9
8
222
79
20
13
79
50
2
6
20
9
45
122
18
12
3511
132
38
23
132
182
2
17
36
16.40%
38.70%
49.80%
23.60%
7.80%
55.70%
42.20%
17.70%
28.00%
42.20%
31.50%
3.22%
10.50%
33.90%
MVGVPAAFDMMLTGR
MVNHFIAEFK
MVVEHPEFLK
MVVTNLLTR
NAEAVLQGPGISGK
NAEQFKDQADK
NALAHALQSSR
NALWHTGNTPGQVR
NAVITVPAYFNDSQR
NAYEEALDQLETVK
NAYEEALDQLETVKR
NDLAAVDVR
NEGTATYAAAVLFR
NELESYAYSLK
K
R
R
R
R
K
R
K
K
K
K
R
R
N
R
A
N
V
A
H
T
Q
R
E
T
I
N
54.2
50.8
35.6
39.8
82
78.1
69.8
25.8
47.3
99.2
95.4
64.5
87.3
69.6
29.7
28.8
28.4
26.9
27.2
28.3
27.7
28.6
29.2
29.4
29.4
26.8
28.1
28.4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
3
4
4
4.70%
NESLAQYNPK
R
L
55.5
27.8
2
582.2888
1,162.56
1,163.57
2
0.14
410
419
TRUE
27
50
43
2
26
13
33
65
59
2
29
16
100
289
215
2
46
23
50.10%
48.90%
45.00%
4.14%
40.80%
21.80%
NETEDQYSLMEDEDALPHHEER
NFHVFYQLLEGGEEEALR
NFHVFYQLLEGGEEEALRR
NFILDQTNVSAAAQR
NFITAEELR
NFLDR
K
R
R
R
K
K
T
R
L
R
R
K
62
88.3
56.7
110
60
30.5
30.9
30.3
29.8
28.5
27.4
26.5
2
2
2
2
2
2
M10:Oxidation(+15.99)
901.7114
1,076.03
769.7233
824.4274
546.7885
664.3427
2,702.11
2,150.05
2,306.15
1,646.84
1,091.56
663.3349
2,703.11
2,151.05
2,307.15
1,647.85
1,092.57
664.3419
3
2
3
2
2
1
2.50
1.89
0.92
0.91
0.03
1.25
593
217
217
550
860
218
614
234
235
564
868
222
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
15
107
123
119
40
4
2
5
58
17
169
194
194
51
4
3
5
67
28
1242
2027
3095
216
24
20
6
363
18.40%
49.10%
52.30%
51.60%
43.40%
15.10%
19.20%
12.60%
40.00%
NGDDLRQDMLTLQIIR
NGFEPASLK
NGFEPASLKEEVGEEAIVELVENGK
NGFEPASLKEEVGEEAIVELVENGKK
NGHLAVVAPR
NHEEEMLALR
NHEEEMNALR
NHQSVAEYNIFEGMELR
NILAEQLQAETELFAEAEEMR
K
K
K
K
K
K
K
K
K
I
E
K
V
L
G
G
G
A
44.8
51.7
59.6
65.2
69.1
46
38.4
36.8
85.8
28.8
27.4
29.6
28.1
24.3
28.8
27.5
31.3
30.1
2
2
2
2
2
2
2
2
2
M9:Oxidation(+15.99)
639.6673
481.7508
896.4531
939.1524
517.2991
419.8685
629.7786
684.9895
1,226.10
1,915.98
961.486
2,686.34
2,814.43
1,032.58
1,256.58
1,257.54
2,051.95
2,450.18
1,916.99
962.4948
2,687.34
2,815.44
1,033.59
1,257.59
1,258.55
2,052.94
2,451.17
3
2
3
3
2
3
2
3
2
0.24
1.04
0.70
1.62
0.32
0.07
0.61
3.94
4.85
803
39
39
39
1031
243
231
537
927
818
47
63
64
1040
252
240
553
947
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
4
77
52
44
3
138
31
38
17
18
4
85
69
55
3
222
42
44
23
24
4
149
255
144
3
3511
126
150
474
456
12.00%
47.90%
53.00%
47.80%
6.77%
55.70%
34.10%
29.70%
26.70%
28.30%
NIVEEIEDLVAR
NKDPLNETVVGLYQK
NKDTLFQDFK
NKDTLFQDFKR
NKGDEEEEEEKLEEK
NKHEAMITDLEER
NKHLVALYTR
NKQEVMISDLEER
NKYEDEINK
NKYEDEINKR
R
K
K
K
K
K
K
R
K
K
L
S
R
L
Q
L
D
L
R
T
77.1
59.3
53.9
38.1
34.3
73.2
25.5
87.5
46.7
58.1
27.3
28.1
28
27.9
29.8
29.5
25.3
29.3
31
28.9
2
2
2
2
2
2
2
2
2
2
700.3787
859.4622
628.3206
471.2496
612.2793
534.5918
405.5726
803.8928
576.7811
436.8899
1,398.74
1,716.91
1,254.63
1,410.73
1,833.81
1,600.75
1,213.69
1,605.77
1,151.55
1,307.65
1,399.74
1,717.91
1,255.63
1,411.73
1,834.82
1,601.76
1,214.70
1,606.77
1,152.55
1,308.65
2
2
2
3
3
3
3
2
2
3
4.39
2.30
0.71
0.15
1.48
0.10
0.83
1.85
0.46
0.72
179
598
523
523
536
1023
80
1067
252
252
190
612
532
533
550
1035
89
1079
260
261
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
3
12
3
3
76
2
31
27
9
9
123
58
29
27
15
55
138
49
10
5
14
9
42
3
5
18
27
9
11
4
3
15
2
17
43
46
19
18
138
7
6
13
18
70
70
42
13
119
132
55
8
10
3
15
3
3
92
2
39
29
9
9
194
67
39
29
15
62
222
53
10
6
16
9
59
3
6
19
29
9
11
4
3
15
2
18
59
58
20
22
222
8
6
13
22
82
82
53
15
194
196
59
9
10
3
42
7
5
323
2
145
29
9
9
2027
363
105
29
21
146
3511
157
17
8
50
11
381
3
8
19
29
9
12
4
3
29
2
25
215
181
52
56
3511
14
12
13
56
145
145
149
45
3095
883
166
12
15
6.58%
36.40%
9.76%
11.60%
46.50%
6.29%
31.80%
21.50%
16.70%
16.40%
52.30%
40.00%
67.20%
21.50%
13.60%
37.80%
55.70%
33.40%
14.60%
12.30%
22.30%
12.10%
43.80%
11.70%
19.20%
14.40%
21.50%
13.30%
15.90%
3.84%
15.80%
24.60%
3.55%
20.40%
45.00%
39.90%
33.50%
37.30%
55.70%
17.20%
16.20%
12.60%
37.30%
45.50%
45.50%
45.40%
37.80%
51.60%
55.20%
38.10%
4.68%
13.90%
NLANTVTEEILEK
NLDIERPTYTNLNR
NLDLDSIIAEVR
NLDLDSIIDEVR
NLEQEIADLTEQIAENGK
NLHQSGFSLSGAQIDDNIPR
NLIGIYR
NLILVVR
NLLHVTDTGVGMTR
NLNSEIDNILVNLR
NLPIYSEEIVDMYK
NLPIYSENIIEMYR
NLQEAEEWYK
NLQNLLILTAIK
NLSPGAVESDVR
NLTEELAGLDETIAK
NMDPLNDNIATLLHQSSDK
NMDPLNDNVATLLHQSSDR
NMSVIAHVDHGK
NMTEALLELHGHSR
NMVNEEDESQDTETVFK
NMVPQQALVIR
NNDLLFR
NNDPDTTEVNLNNIENITTQTLSR
NNDPELEEVNLNNIR
NNLAGAEELFAR
NNRPSEGPLQTR
NNTALQSVSLR
NNVAFMSYFLQGK
NPAVLSAASFDGR
NPDDITNEEYGEFYK
NPDDITQEEYGEFYK
NPEQVDLYQFMAK
NPGNQAAYEHFETMK
NPQSYLYLVK
NPSSAVPPLAGSVK
NQLTSNPENTVFDAK
NQVAMNPTNTVFDAK
NREEAIK
NRPPPLVEITPR
NSASATTPLSGNSSR
NSIAYLDEETGR
NSLESYAFNMK
NSLQEQQEEEEEAR
NSLQEQQEEEEEARK
NSMIALVDNLASK
NSSYFVEWIPNNVK
NTDQASMPDNTAAQK
NTDQASMPDNTAAQK
NTDQASMPENTVAQK
NTFAEVTGLSPGVTYLFK
NTITHVSSPGTVTR
R
R
R
R
K
R
K
K
K
K
K
K
K
R
K
K
K
K
R
R
R
K
K
K
K
R
K
R
K
R
R
R
K
R
R
R
K
K
K
R
R
K
K
K
K
K
K
R
R
R
R
K
S
L
A
A
S
R
L
G
E
L
G
G
S
A
G
L
F
F
S
R
E
N
N
F
N
K
L
S
L
I
S
S
D
N
G
T
R
R
Q
D
R
L
A
K
N
E
T
V
V
L
V
L
52.8
53.5
83.2
69.1
63.9
34.9
36.2
29.5
48.3
75.7
95.1
95.9
45.5
80.1
46.7
107
90.8
45
67
41.3
128
27.5
47.1
73.7
85.1
81.1
53.1
76.7
37.4
73.2
84.6
83.6
67.7
28.7
57.4
80.3
85.9
100
34
45.9
65.7
79.1
60.9
68.4
47.9
91.3
37.9
95.9
71
75.5
62.3
63.1
27.7
28.5
26.9
28.9
29.4
29.5
22.6
17.9
28.4
26.4
30
29.4
28.8
14.1
28.1
28
30.3
31.1
28.4
29.5
29.5
26.1
27.6
30.4
29.7
28.2
28.1
26.4
29.4
28.4
29.4
30
29.7
29.5
26
26.3
29.8
29.4
26.6
23.9
28.8
29
28.6
29.9
30.1
28.2
29.7
29.7
29.6
29.8
27.1
27.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
737.397
859.9467
679.371
701.366
672.3399
723.6978
848.5004
413.7807
765.3939
813.9479
865.4226
885.9432
655.3073
677.4298
622.3198
808.926
1,071.51
719.3403
662.327
541.936
1,015.93
642.8616
446.2383
906.1094
891.9387
652.8377
684.8554
601.8298
767.8763
652.8366
917.3955
924.4042
799.8834
584.9273
612.8364
662.3676
839.4088
833.4
859.4644
463.6056
725.3511
684.3279
660.3015
859.8812
923.9282
696.3637
848.9246
804.3541
796.3585
825.3778
972.5151
490.5958
1,472.78
1,717.88
1,356.73
1,400.72
2,014.00
2,168.07
847.4925
825.5458
1,528.77
1,625.88
1,728.83
1,769.87
1,308.60
1,352.84
1,242.62
1,615.84
2,141.01
2,155.00
1,322.64
1,622.78
2,029.85
1,283.71
890.461
2,715.30
1,781.86
1,303.66
1,367.70
1,201.64
1,533.74
1,303.66
1,832.78
1,846.79
1,597.75
1,751.76
1,223.66
1,322.72
1,676.80
1,664.78
858.4566
1,387.79
1,448.69
1,366.64
1,318.59
1,717.75
1,845.84
1,390.71
1,695.83
1,606.69
1,590.70
1,648.74
1,943.01
1,468.76
1,473.78
1,718.88
1,357.73
1,401.72
2,014.99
2,169.07
848.4995
826.5515
1,529.77
1,626.88
1,729.84
1,770.87
1,309.61
1,353.85
1,243.63
1,616.84
2,142.01
2,156.00
1,323.65
1,623.79
2,030.85
1,284.71
891.469
2,716.30
1,782.86
1,304.66
1,368.70
1,202.65
1,534.74
1,304.66
1,833.78
1,847.80
1,598.75
1,752.77
1,224.66
1,323.73
1,677.81
1,665.79
859.4638
1,388.80
1,449.69
1,367.64
1,319.59
1,718.75
1,846.84
1,391.72
1,696.83
1,607.70
1,591.70
1,649.74
1,944.01
1,469.77
2
2
2
2
3
3
1
2
2
2
2
2
2
2
2
2
2
3
2
3
2
2
2
3
2
2
2
2
2
2
2
2
2
3
2
2
2
2
1
3
2
2
2
2
2
2
2
2
2
2
2
3
4.08
1.73
1.11
0.98
5.17
3.90
1.05
2.63
3.46
4.08
0.87
2.85
0.22
3.36
2.78
3.50
0.64
0.41
1.26
0.55
1.58
4.40
0.09
3.74
4.20
5.92
3.33
2.16
5.59
4.24
0.62
1.61
3.99
0.65
1.73
0.03
0.82
1.05
0.68
0.50
0.87
2.71
0.86
4.35
3.52
0.59
4.77
1.92
4.32
2.17
5.42
0.44
344
216
295
295
1505
533
173
831
143
647
126
167
283
1023
171
978
588
632
21
125
267
163
543
214
192
355
572
101
725
315
301
292
544
685
241
1280
82
57
1633
464
116
1280
540
1383
1383
570
337
359
359
403
958
506
356
229
306
306
1522
552
179
837
156
660
139
180
292
1034
182
992
606
650
32
138
283
173
549
237
206
366
583
111
737
327
315
306
556
699
250
1293
96
71
1639
475
130
1291
550
1396
1397
582
350
373
373
417
975
519
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
57
20
42
11
14
119
28
52
29
22
2
66
26
59
12
14
194
41
69
33
26
2
435
63
381
13
15
3095
122
255
58
34
5.36%
39.20%
26.80%
43.80%
30.70%
20.80%
51.60%
49.80%
53.00%
15.80%
41.70%
NTLFNLSNFLDK
NTNPNFVR
NTSVVDSEPVR
NVLDTSWPTPPPALR
NVQAEEMVEFSSGLK
NVTVQPDDPISFMQLTAK
NWQWWR
NWRDPDQTDGPGLSYLSSHIANVER
NYDTTVHGK
NYGFQIHTK
NYITGDELR
R
R
R
R
R
R
R
K
K
R
K
S
C
F
E
G
N
L
V
N
E
R
45.6
56
80.7
59.9
60.8
60.2
34.4
76.1
44
47.3
47
27.6
28.4
28.2
27.8
29.3
29.3
27.2
30.9
26.7
28
28.2
2
2
2
2
2
2
2
2
2
2
2
713.3762
481.2474
601.8051
832.4454
842.4022
1,010.51
488.2337
943.1231
517.7496
554.2836
540.7705
1,424.74
960.4791
1,201.59
1,662.88
1,682.79
2,019.01
974.4518
2,826.35
1,033.48
1,106.55
1,079.53
1,425.74
961.4856
1,202.60
1,663.88
1,683.79
2,020.01
975.4588
2,827.34
1,034.49
1,107.56
1,080.53
2
2
2
2
2
2
2
3
2
2
2
4.74
1.37
0.64
1.12
3.87
5.40
0.85
4.72
0.63
0.59
0.49
101
707
570
808
89
662
824
344
367
417
841
112
714
580
822
103
679
829
368
375
425
849
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M6:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M6:Oxidation(+15.99)
M11:Oxidation(+15.99)
M14:Oxidation(+15.99)
M5:Oxidation(+15.99)
M10:Oxidation(+15.99)
M3:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M7:Oxidation(+15.99)
M13:Oxidation(+15.99)
IPI00213463
IPI00197888
IPI00197888
IPI00230775
IPI00551773
IPI00475639
IPI00197888
IPI00454475,IPI00551558,IPI00207038
IPI00230775
TRUE
TRUE
83516
M6:Oxidation(+15.99)
1,443.80
2
124233
233603
111895
57499
82649
60567
M6:Oxidation(+15.99)
M6:Oxidation(+15.99)
M14:Oxidation(+15.99)
M20:Oxidation(+15.99)
1,442.79
1,459.70
81251
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M16:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M3:
Oxidation(+15.99),M10:
Oxidation(+15.99)
M1:Oxidation(+15.99),M3:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99),M10:
Oxidation(+15.99),M11:
Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
M1:Oxidation(+15.99)
481.9382
1,458.70
IPI00393867,IPI00331979,IPI00391496
IPI00388110,IPI00207988,IPI00331979
IPI00391300,IPI00558912
IPI00362534
493.2557
1,476.74
1,477.75
3
0.36
554
565
TRUE
548.7642
753.0077
675.7979
670.3093
660.8593
742.647
1,095.51
2,256.00
1,349.58
1,338.60
1,319.70
2,224.92
1,096.52
2,257.00
1,350.58
1,339.61
1,320.71
2,225.92
2
3
2
2
2
3
0.15
1.26
2.38
0.12
1.51
1.61
282
985
966
383
506
131
290
1003
976
393
516
150
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
810.4191
1,175.03
955.4699
1,618.82
2,348.05
1,908.92
1,619.82
2,349.05
1,909.92
2
2
2
5.45
1.42
5.13
495
941
352
509
959
366
TRUE
TRUE
TRUE
772.7035
460.8947
596.306
937.476
916.9749
665.8928
643.3287
2,315.09
1,379.66
1,190.60
1,872.94
1,831.93
1,329.77
1,284.64
2,316.09
1,380.67
1,191.60
1,873.94
1,832.93
1,330.78
1,285.65
3
3
2
2
2
2
2
4.08
0.59
0.07
3.80
5.75
0.67
2.78
193
318
237
363
178
587
294
212
330
246
379
194
597
304
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00195673
657.966
1,970.87
1,971.88
3
0.04
321
336
TRUE
IPI00475639
536.2634
610.8018
459.5713
1,122.12
654.8218
1,070.51
1,219.59
1,375.69
2,242.22
1,307.63
1,071.52
1,220.59
1,376.70
2,243.21
1,308.64
2
2
3
2
2
1.06
1.13
1.89
7.15
0.06
348
191
191
81
709
356
201
202
101
720
TRUE
FALSE
FALSE
TRUE
TRUE
822.3839
626.314
622.8229
531.8035
670.8635
647.3079
584.3153
517.6006
847.9296
811.9016
889.9511
486.7593
742.3857
658.8231
1,642.75
1,250.61
1,243.63
1,061.59
1,339.71
1,292.60
1,166.61
1,549.78
1,693.84
1,621.79
1,777.89
971.5029
1,482.76
1,315.63
1,643.76
1,251.62
1,244.64
1,062.60
1,340.72
1,293.61
1,167.62
1,550.78
1,694.85
1,622.79
1,778.89
972.5116
1,483.75
1,316.64
2
2
2
2
2
2
2
3
2
2
2
2
2
2
0.17
0.42
2.48
1.07
1.21
0.22
0.60
2.07
0.81
2.43
0.98
0.90
6.20
0.77
191
237
1
324
849
1858
1328
1078
188
1487
1487
339
638
563
205
246
10
332
862
1868
1338
1091
202
1500
1501
347
651
573
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00370073
IPI00370073
IPI00370073
IPI00454475
IPI00454475
IPI00195673,IPI00475639
IPI00558912
IPI00558912
IPI00367479,IPI00558912
Irs1
Irs1
Gsn
Tmpo
Col1a2
Mprip
LOC682005;G
apdh;LOC685
186
Mprip
Myh9
Pik3r2
Myo1d
Canx
Kpnb1
Myo1c
Pik3r1
Cald1
Clip2
Eef2
Lmo7
Irs1
Fn1
Hspa9
Myh3
Ptrf
Myh3
Myh9
Clip2
Arhgef2
Hspa9
Pik3ca
Vim
Mprip
Myh3
Nexn
Mprip
Copa
Nexn
Acta1
Actb
Krt17
Hnrpm
Ppp1r12a
Rai14
Myo1d
Myh9
Myh9
Dpysl3
Arhgef2
Sdpr
Immt
Myh10
Cald1
Myo1c
Myh9
Myh9
Tnnt3
Kif5b
Tpm1
Tpm1
Myh9
Myh10
Tpm2
Tpm2
Kif5b
Actn4
Tmod3
Tuba1b
Eef1a1
Rrbp1
Myo1c
Myh9
Myh10
Myh14
Myh14
Rai14
Dsp
Rai14
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Isoform2ofGelsolin
75kDaprotein
Collagenalpha2(I)chain
258kDaprotein
IPI00199662
IPI00199662
IPI00923716
IPI00569391
IPI00188921
IPI00392930
Glyceraldehyde3phosphatedehydrogenase
IPI00555252,IPI00567177
258kDaprotein
IPI00392930
Myosin9
IPI00209113
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
MyosinId
IPI00207989
Calnexin
IPI00199636
Importinsubunitbeta1
IPI00204261
MyosinIc
IPI00393867
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
Caldesmon
IPI00208118
111kDaprotein
IPI00476704
Elongationfactor2
IPI00203214
LMO7b
IPI00421345
Insulinreceptorsubstrate1
IPI00199662
Isoform1ofFibronectin
IPI00200757,IPI00231982,IPI00231983
Stress70protein,mitochondrial
IPI00363265
Myosin3
IPI00201578
PolymeraseIandtranscriptreleasefactor
IPI00201300
Myosin3
IPI00201578
Myosin9
IPI00209113
111kDaprotein
IPI00476704
Rhoguaninenucleotideexchangefactor2
IPI00368617
Stress70protein,mitochondrial
IPI00363265
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
Vimentin
IPI00230941
258kDaprotein
IPI00392930
Myosin3
IPI00201578
Isoform1ofNexilin
IPI00209938
258kDaprotein
IPI00392930
Copaprotein
IPI00372458
Isoform1ofNexilin
IPI00209938
Actin,alphaskeletalmuscle
IPI00189813
Actin,cytoplasmic1
IPI00189819,IPI00765011,IPI00896224
Keratin,typeIcytoskeletal17
IPI00370073
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
Isoform2ofAnkycorbin
IPI00372146
MyosinId
IPI00207989
Myosin9
IPI00209113
Myosin9
IPI00209113
Isoform2ofDihydropyrimidinaserelatedprotein3 IPI00203250
Rhoguaninenucleotideexchangefactor2
IPI00368617
Serumdeprivationresponseprotein
IPI00362416
82kDaprotein
IPI00364895,IPI00566985
234kDaprotein
IPI00391300
Caldesmon
IPI00208118
MyosinIc
IPI00393867
Myosin9
IPI00209113
Myosin9
IPI00209113
131160
131160
80911
74885
129547
257845
38
30
28
3
13
40
51
42
41
3
13
54
99
108
122
3
13
117
40.60%
29.50%
49.80%
6.79%
12.60%
19.90%
PASVDGSPVSPSTNR
PASVDGSPVSPSTNR
PDLPQGTEDTAK
PEFLEDPSVLTK
PGPIGPAGPR
PIQQALAQER
R
R
K
M
R
R
T
T
E
D
G
A
86.1
77.6
49.4
40
34.1
69.4
28.9
28.7
28.6
28.2
27
26.4
2
2
2
2
2
2
35810
257845
226326
8
40
119
9
51
194
16
83
3095
27.90%
21.50%
51.60%
PITIFQER
PIYGGWLLLAPDGTDFDNPVHR
PLLNSIR
K
K
K
D
S
H
44.3
49.3
32.3
27.3
29.5
21.1
2
2
2
81251
116081
67239
97167
119797
27
42
3
8
42
33
53
3
8
59
100
149
3
9
381
50.10%
45.40%
6.77%
13.20%
43.80%
PLPARPLDGPSESGHTLASLAEQFSPPEPAPPILVK
PLTAATLFK
PMIDNPNYK
PMIHELLTEGR
PQDGVAVLVR
R
R
R
R
R
L
N
G
R
H
21
43.8
29.7
49.6
76.3
24.1
22
27.4
27.9
22.1
2
2
2
2
2
83516
60567
111364
95268
156634
131160
272486
73840
223846
43891
223846
226326
111364
111895
73840
10
15
20
10
35
38
8
10
68
3
47
138
28
9
9
11
18
21
10
43
51
9
10
78
3
50
222
31
9
9
19
41
36
13
112
99
12
14
99
3
182
3511
43
9
11
17.10%
33.00%
22.60%
12.80%
30.80%
40.60%
4.68%
20.30%
43.10%
12.80%
31.50%
55.70%
34.30%
13.30%
18.90%
PRPPRPLPVAPGSSK
PSDLRPGDVSGK
PSIGSASSSVVASASGSK
PSQVVAETR
PSSLSSSQQSWSTR
PVLSYYSLPR
PYLPNVDEEVQIGHVPR
QAASSLQQASLK
QAEEADEQANVHLTK
QAEMEGAVQSIQGELSK
QAFTQQIEELKR
QAQQERDELADEIANSSGK
QASGPSSAGATTTVSEKPGPK
QATELALLQR
QAVTNPNNTFYATK
K
K
R
R
R
K
R
R
R
R
K
R
K
K
R
T
R
E
K
G
S
G
L
F
L
Q
G
A
Q
R
23.5
48.8
117
60.2
113
55.5
42.9
56.4
77.2
83.8
45.6
91.4
49
27.7
81.2
23.3
27.2
29.1
26.7
29.1
28.7
27.8
27.7
29.7
29.6
27.1
29.9
29.5
26.7
29.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
124233
53716
257845
223846
78377
257845
138346
78377
42034
41720
48106
77613
115268
105981
116081
226326
226326
73882
111895
46368
82231
233603
60567
119797
226326
226326
10
27
37
55
20
37
15
15
2
6
15
6
7
43
43
132
113
5
9
4
6
58
7
43
132
132
11
34
49
62
26
49
15
20
3
12
18
6
7
50
53
196
179
5
9
4
7
67
8
59
196
196
17
107
105
146
63
105
21
49
8
140
43
6
9
62
221
883
1862
6
9
5
7
363
14
215
883
883
10.10%
60.90%
19.50%
37.80%
26.80%
19.50%
13.60%
23.90%
52.80%
48.50%
34.40%
12.20%
8.33%
48.90%
48.10%
55.20%
50.90%
12.60%
13.30%
12.20%
14.00%
40.00%
17.50%
45.00%
55.20%
55.20%
QDMLTLQIIR
QDVDNASLAR
QEAEPGEPDPEQK
QEAPPHIFSISDNAYQFMLTDR
QEFEQLR
QEISSLKDELQTALR
QELILSNSEDK
QEMGKEEEENESFGLSR
QEYDEAGPSIVHR
QEYDESGPSIVHR
QFTSSSSIK
QGGGGAGGSVPGIER
QGVDIEAAR
QHQEVVSVYR
QHTEQEASYGR
QIATLHAQVTDMK
QIATLHAQVTDMKK
QIGDNLIVPGGVK
QILSQSTDSLNMR
QINLEGSVK
QIVEILTTYASAVGIGTTQVQQE
QIVSNLEK
QKEFDPTITDGSLSVPSR
QKGDVVLQSDHVIETLTK
QKHSQAVEELAEQLEQTK
QKHSQAVEELAEQLEQTKR
R
R
K
R
K
K
R
R
K
K
R
K
R
K
K
K
K
K
R
R
K
R
R
K
R
R
I
L
K
E
Q
D
S
E
K
K
G
M
K
M
D
K
K
T
N
G
K
R
T
R
V
34.4
68.9
64.1
70.1
44.3
103
44.6
61.3
65.2
65.9
39.7
67.2
54.8
43.4
39.7
62.7
68.1
29.2
59.4
48.8
64.2
34.7
79.6
41.1
34.6
46.3
27.3
28
29
31.3
27.8
27.1
28.4
29.9
29.7
29.3
26.5
28.8
25.9
28.3
28.3
28.5
27.6
24.3
29.2
28.2
26.9
27.1
29.8
26.4
28.5
27.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00364904
109514
IPI00210945
32831
IPI00210945
32831
IPI00209113
226326
IPI00391300
233603
IPI00187731
32941
IPI00187731
32941
IPI00364904
109514
IPI00213463
104900
IPI00373505
39455
IPI00339167
50134
IPI00195372,IPI00551729
50096
IPI00188079
143655
IPI00393867
119797
IPI00209113
226326
IPI00391300
233603
IPI00367479
229088
IPI00367479
229088
IPI00372146
105981
IPI00366081
332383
IPI00372146
105981
7
13
27
25
111
57
4
3
13
28
6
11
8
12
47
111
57
3
3
34
9
43
10
13
41
40
172
66
5
3
13
34
7
13
10
12
62
172
66
3
3
39
9
50
18
13
231
228
2414
435
14
8
13
49
8
47
25
15
175
2414
435
23
23
69
21
62
30.50%
17.30%
50.70%
48.90%
50.00%
39.20%
74.30%
63.00%
17.30%
39.60%
21.90%
34.60%
21.60%
10.90%
46.60%
50.00%
39.20%
5.15%
5.15%
39.20%
3.75%
48.90%
QKYDITTLR
QLDDKDEEINQQSQLVEK
QLEDELVSLQK
QLEDELVSLQKK
QLEEAEEEAQR
QLEEAEEEATR
QLEEELR
QLEEEQQALQK
QLEESVDSLGEELVQLR
QLETIDQLHLEYAK
QLETVLDDLDPENALLPAGFR
QLFHPEQLITGK
QLIVGVNK
QLLLDSQSQLEEAK
QLLLTPSAVVIVEDAK
QLLQANPILEAFGNAK
QLLQANPILESFGNAK
QLLSTLEK
QLLSTLEK
QLQDELQSQR
QLQNIIQATSR
QLSDVSSPR
R
K
K
K
R
R
R
K
R
K
K
R
K
R
R
R
R
K
K
K
R
K
S
L
K
L
A
A
T
K
A
R
Q
E
M
S
V
T
T
K
K
T
E
S
50.9
27.2
60.7
26.3
65.1
68.6
67.2
77.4
58.7
25.8
75
38.5
42.3
40.8
101
105
81.6
33.2
33.2
60
58.1
55.4
25.6
29.7
27.8
25.7
28.3
29.1
26.7
28.8
28.1
27.9
28
26.2
21.6
27.7
20.6
25.3
26.4
27.6
27.6
28.4
26.7
27.4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00365423
IPI00421797
IPI00551773
IPI00209113
65306
50657
45954
226326
2
4
9
138
2
5
12
222
2
10
37
3511
6.45%
12.30%
23.80%
55.70%
QLSQSLLPAIVELAEDAK
QLVEADINGLR
QLVESDINGLR
QMEDEKNSFR
R
R
R
K
W
R
R
E
48.2
64.6
64.6
34.8
24.7
26.3
27.7
28
2
2
2
2
IPI00230941
IPI00325147
IPI00551773
53716
40813
45954
28
3
9
40
5
12
261
10
37
62.20%
10.20%
23.80%
QMREMEENFALEAANYQDTIGR
QNFIQHFSQIVK
QNHEQEVNTLR
R
K
K
L
V
C
51.5
32.4
47.1
31.4
26.4
29
2
2
2
Ppp2r1a
Krt35
Krt33a
Myh9
Isoform1ofTroponinT,fastskeletalmuscle
Kinesin1heavychain
tropomyosin1,alphaisoformc
tropomyosin1,alphaisoformc
Myosin9
234kDaprotein
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
Kinesin1heavychain
Alphaactinin4
Tropomodulin3
Tubulinalpha1Bchain
Elongationfactor1alpha1
similartoRibosomebindingprotein1
MyosinIc
Myosin9
234kDaprotein
myosin,heavychain14
myosin,heavychain14
Isoform2ofAnkycorbin
similartodesmoplakinisoformIisoform2
Isoform2ofAnkycorbin
Proteinphosphatase2(Formerly2A),regulatorysubunitA
(PR65),alphaisoform,isoformCRA_a
TypeIhairkeratinKA30
TypeIhairkeratinKA27
Myosin9
Vim
Fdps
Krt33a
Vimentin
Farnesylpyrophosphatesynthetase
TypeIhairkeratinKA27
Tnnt3
Krt35
Clip2
Clip2
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00421797
50657
IPI00476704
111364
IPI00476704
111364
12
4
30
28
16
5
33
31
46
10
42
43
34.40%
12.30%
33.70%
34.30%
QNKDLMELQALIDSHFEAR
QNQEYQVLLDVR
QPAAEGSGSDAHSVESLTAQNLSLHSGTATPPLTGR
QPAAEGSGSDAHSVESLTAQNLSLHSGTATPPLTGR
R
R
R
R
K
A
V
V
42.1
57.5
28.6
21.7
30.1
28.2
31.1
29.7
2
2
2
2
Pik3ca
Htra1
Lmo7
Copb2
Cald1
Cald1
Clip2
Lmo7
Tmod3
Myh9
Vim
Myh3
Myh9
Krt10
Copb1
Lmo7
Krt10
Krt10
Myh9
Irs1
Isoform1ofTroponinT,fastskeletalmuscle
TypeIhairkeratinKA30
111kDaprotein
111kDaprotein
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
HtrAserinepeptidase1,isoformCRA_a
LMO7b
Coatomersubunitbeta'
Caldesmon
Caldesmon
111kDaprotein
LMO7b
Tropomodulin3
Myosin9
Vimentin
Myosin3
Myosin9
Keratin,typeIcytoskeletal10
Coatomersubunitbeta
LMO7b
Keratin,typeIcytoskeletal10
Keratin,typeIcytoskeletal10
Myosin9
Insulinreceptorsubstrate1
IPI00769069,IPI00769166
IPI00199325
IPI00421345
IPI00231953
IPI00208118
IPI00208118
IPI00476704
IPI00421345
IPI00373505
IPI00209113
IPI00230941
IPI00201578
IPI00209113
IPI00421806,IPI00551673
IPI00211812
IPI00421345
IPI00421806,IPI00551673
IPI00421806,IPI00551673
IPI00209113
IPI00199662
124233
51312
156634
102535
60567
60567
111364
156634
39455
226326
53716
223846
226326
56489
106996
156634
56489
56489
226326
131160
15
6
45
11
13
13
29
21
8
132
38
68
105
13
14
46
14
13
122
31
17
6
54
11
16
16
34
24
10
196
51
78
175
20
14
58
22
22
194
39
28
8
120
12
23
23
49
95
18
883
155
99
2139
283
15
181
365
244
2067
145
18.40%
17.10%
37.60%
15.90%
21.80%
21.80%
32.40%
19.80%
34.70%
55.20%
77.50%
43.10%
47.80%
21.50%
20.80%
39.90%
24.50%
21.50%
51.90%
31.80%
QPDFMDALQGFLSPLNPAHQLGNLR
QPPVIVLQR
QPSYVPAPLRK
QQALTVSTDPEHR
QQEAALELEELK
QQEAALELEELKK
QQHIEQLLAER
QQILQEMR
QQLGTSVELEMAK
QQQLTAMK
QQYESVAAK
QREEQAEPDGTEVADK
QRYEILTPNSIPK
QSLEASLAETEGR
QSLSQMLSAK
QSSWHSQPAGVYASSSVQDFSR
QSVEADINGLR
QSVEADINGLRR
QSVSNLEK
QSYVDTSPVAPVSYADMR
R
R
K
K
K
K
K
R
R
R
R
K
R
K
R
R
R
R
R
R
L
G
K
F
K
K
D
K
M
V
N
T
G
Y
L
L
R
V
K
T
41.6
33.5
21.2
36.9
75.3
61.3
30.3
42.7
54.8
54.2
33
53.8
47.5
115
53
70.9
84.9
42.7
56.5
87.2
29.4
17.2
24.6
29.1
28.4
27.9
27.5
28.3
28.6
28.1
26.9
29.7
26
29.1
27.9
31.3
27.6
27.5
28.2
30.7
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Irs1
Cald1
Immt
Myh9
Myh9
Rai14
Hspa8
Gsn
Vim
Mybph
Myh10
Mprip
Lmo7
Vim
Rai14
Thbs1
Ldha
Mprip
Anxa2
Nexn
Myo1d
Myo1c
Myh3
Hsp90ab1
Actn4
Myo1c
Lmo7
Myh9
Myo1d
Mprip
Myh9
Insulinreceptorsubstrate1
Caldesmon
82kDaprotein
Myosin9
Myosin9
Isoform2ofAnkycorbin
Heatshockcognate71kDaprotein
Isoform2ofGelsolin
Vimentin
53kDaprotein
234kDaprotein
258kDaprotein
LMO7b
Vimentin
Isoform2ofAnkycorbin
Thrombospondin1
LlactatedehydrogenaseAchain
258kDaprotein
IsoformShortofAnnexinA2
Isoform1ofNexilin
MyosinId
MyosinIc
Myosin3
HeatshockproteinHSP90beta
Alphaactinin4
MyosinIc
LMO7b
Myosin9
MyosinId
258kDaprotein
Myosin9
IPI00199662
IPI00208118
IPI00364895,IPI00566985
IPI00209113
IPI00209113
IPI00372146
IPI00208205
IPI00923716
IPI00230941
IPI00557294
IPI00391300
IPI00392930
IPI00421345
IPI00230941
IPI00372146
IPI00422076
IPI00197711
IPI00392930
IPI00325146
IPI00209938
IPI00207989
IPI00393867
IPI00201578
IPI00471584
IPI00213463
IPI00393867
IPI00421345
IPI00209113
IPI00207989
IPI00392930
IPI00209113
131160
60567
82231
226326
226326
105981
70855
80911
53716
52762
233603
257845
156634
53716
105981
129653
36433
257845
38662
78377
116081
119797
223846
83266
104900
119797
156634
226326
116081
257845
226326
28
15
6
132
105
26
18
14
38
4
49
37
38
28
26
19
3
35
8
16
52
50
77
25
14
50
46
122
44
37
138
39
18
7
196
175
30
22
17
51
4
53
49
47
40
32
20
3
51
11
18
69
65
85
26
15
72
58
194
55
49
222
93
41
7
883
2139
44
37
72
155
5
157
105
123
261
60
38
5
95
13
31
255
289
149
38
20
328
181
2067
144
105
3511
31.30%
33.00%
14.00%
55.20%
47.80%
32.80%
39.00%
31.50%
77.50%
14.40%
33.40%
19.50%
31.90%
62.20%
31.90%
17.70%
10.50%
18.00%
30.10%
22.40%
53.00%
48.90%
47.90%
37.00%
20.90%
48.80%
39.90%
51.90%
47.80%
19.50%
55.70%
QSYVDTSPVAPVSYADMR
QTENAFSPSR
QTITAQNAAVQAVK
QTLENER
QTLENERGELANEVK
QTQQLEMLQQQVK
QTQTFTTYSDNQPGVLIQVYEGER
QTQVSVLPEGGETPLFK
QVDQLTNDK
QVGESVNLQIPFQGK
QVLALQSQLADTK
QVPIAPLHLSLEDR
QVPLVSAEPHQASSFSSTEPHQASLSSALQR
QVQSLTCEVDALK
QVSELSQLYR
QVTQSYWDTNPTR
QVVDSAYEVIK
QYLEELQSVQR
RAEDGSVIDYELIDQDAR
RAEQEGDDSLLITVVPAK
RAGFAFR
RAGFAYR
RANLLQAEVEELR
RAPFDLFENK
RDHALLEEQSK
RDQAVMISGESGAGK
REEESSGLLPIDR
REQEVSILK
RFEEALQSIFNR
RFFILYEHGLLR
RGDMPFVVTR
R
K
R
K
K
R
K
R
R
R
K
K
R
R
K
K
K
R
K
K
R
R
R
R
K
R
K
K
R
R
R
T
S
A
G
A
Q
A
Q
A
P
K
S
P
G
E
A
L
E
E
S
Q
R
A
K
Q
T
S
K
W
Y
R
77.3
56.1
69
47.7
65.9
69.5
62.8
75.3
46.4
47.2
90.7
43.3
69.2
47.5
69.8
96.7
43.9
69.3
56
89.1
28.8
31.9
80.7
34.2
58.7
90.3
56.9
49.4
63.1
54.4
54.7
30.5
27.2
26.8
25.3
29.2
28.9
30.8
28
27.6
26.8
26
25.3
29.1
28.6
28
29.1
26.8
28.6
30.8
27.5
25.5
24.4
26.7
28.2
27.9
29.1
29
26.8
28.5
24.7
28.7
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Irs1
Myh10
Acta1
Htra1
Myh9
Irs1
Irs1
Irs1
Nexn
Tpm2
Tpm2
Myh9
Myo1c
Clip2
Nes
Ckap4
Cald1
Sdpr
Kb23
Cald1
Hsp90ab1
Vim
Nexn
Myo1c
Akt1
Lmo7
Cltc
Cltc
Myo1d
Nes
Insulinreceptorsubstrate1
234kDaprotein
Actin,alphaskeletalmuscle
HtrAserinepeptidase1,isoformCRA_a
Myosin9
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Isoform1ofNexilin
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
Myosin9
MyosinIc
111kDaprotein
Isoform1ofNestin
cytoskeletonassociatedprotein4
Caldesmon
Serumdeprivationresponseprotein
TypeIIkeratinKb23
Caldesmon
HeatshockproteinHSP90beta
Vimentin
Isoform1ofNexilin
MyosinIc
RACalphaserine/threonineproteinkinase
LMO7b
Clathrinheavychain1
Clathrinheavychain1
MyosinId
Isoform1ofNestin
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
Myosin9
Myosin9
Myosin9
Isoform2ofAnkycorbin
Vimentin
Insulinreceptorsubstrate1
Isoform1ofNexilin
centaurin,gamma2
LMO7b
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
septin9isoform1
septin9isoform1
Keratin,typeIIcytoskeletal1
Isoform2ofGelsolin
Leiomodin2
IPI00199662
IPI00391300
IPI00189813
IPI00199325
IPI00209113
IPI00199662
IPI00199662
IPI00199662
IPI00209938
IPI00187731
IPI00187731
IPI00209113
IPI00393867
IPI00476704
IPI00194103
IPI00365982
IPI00208118
IPI00362416
IPI00454476,IPI00780672
IPI00208118
IPI00471584
IPI00230941
IPI00209938
IPI00393867
IPI00212844
IPI00421345
IPI00193983
IPI00193983
IPI00207989
IPI00194103
131160
233603
42034
51312
226326
131160
131160
131160
78377
32941
32941
226326
119797
111364
208776
63529
60567
46368
62207
60567
83266
53716
78377
119797
55719
156634
191585
191585
116081
208776
38
58
2
8
107
38
30
30
17
3
4
138
43
18
16
11
15
5
11
15
25
38
20
42
6
39
27
9
42
16
51
67
4
8
169
51
42
40
21
4
5
222
59
18
17
11
15
6
14
15
26
51
26
59
8
49
29
9
50
17
99
363
23
14
1242
99
108
85
50
12
14
3511
215
21
27
17
27
12
39
27
38
155
63
381
16
116
29
10
166
27
40.60%
40.00%
58.60%
23.50%
49.10%
40.60%
29.50%
31.60%
24.10%
64.80%
74.30%
55.70%
45.00%
17.90%
10.50%
25.70%
29.80%
14.60%
13.30%
29.80%
37.00%
77.50%
26.80%
43.80%
16.00%
32.70%
21.50%
9.01%
46.10%
10.50%
RGGHHRPDSSNLHTDDGYMPMSPGVAPVPSNR
RGGPISFSSSR
RGILTLK
RGNEDIVITVVPEEIDP
RHEMPPHIYAITDTAYR
RHSSETFSAPTR
RHSSETFSAPTR
RHSSETFSAPTR
RIEQDLLEK
RIQLVEEELDR
RIQLVEEELDRAQER
RKLEGDSTDLSDQIAELQAQIAELK
RKYEAFLQR
RLEAELEAVSR
RLEAYLTR
RLEEELQQLK
RLEELR
RLENNHAQLLR
RLLEGEEQR
RLQEALER
RLSELLR
RMFGGSGTSSR
RNMVNEEDESQDTETVFK
RPETVATQFK
RPHFPQFSYSASGTA
RPIDSYDLPK
RPISADSAIMNPASK
RPLIDQVVQTALSETQDPEEVSVTVK
RPLTAATLFK
RPPAPPHGSPVR
R
R
K
R
K
R
R
R
R
R
R
R
R
R
R
R
K
K
R
K
R
R
R
K
R
R
R
R
K
R
K
S
Y
S
A
A
A
R
A
L
M
Y
K
V
V
R
R
L
Q
Y
P
E
M
R
V
A
N
A
26.9
56
30.6
33.5
85.8
59.2
50.7
54.7
44.7
66.6
41.8
99
55.1
59.5
37.1
44.8
35.7
40.7
43.7
43.2
30
30.9
41.7
52.3
52.1
45.3
52.7
68.9
39.9
54.5
31.5
28.6
18.8
28.4
30.5
29.3
28.9
28.9
27.6
27.2
27.7
26.8
25.8
27.6
24.7
26.8
26.6
25.8
27.8
26.1
24.1
28.3
30.4
26.7
30
28.5
29.2
25.8
22.3
25.8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00876592
IPI00209113
IPI00209113
IPI00209113
IPI00372146
IPI00230941
IPI00199662
IPI00209938
IPI00389524
IPI00421345
IPI00199662
IPI00199662
IPI00199662
IPI00199662
IPI00215235,IPI00782707
IPI00215235,IPI00782707
IPI00421857
IPI00923716
IPI00372026
102739
226326
226326
226326
105981
53716
131160
78377
96839
156634
131160
131160
131160
131160
64850
64850
64814
80911
61700
11
113
111
122
43
36
33
17
5
38
30
28
38
30
5
5
8
17
7
11
179
172
194
50
48
45
21
5
47
42
39
51
42
5
5
13
22
7
12
1862
2414
2067
62
124
88
50
18
123
108
93
99
108
6
6
278
86
13
19.00%
50.90%
50.00%
51.90%
48.90%
74.00%
36.00%
24.10%
5.23%
31.90%
29.50%
31.30%
40.60%
29.50%
10.80%
10.80%
12.20%
33.80%
14.20%
RPSPEDDLTDDENGDIQLQAQR
RQAQQERDELADEIANSSGK
RQLEEAEEEAQR
RQQQLTAMK
RQTQQLEMLQQQVK
RQVDQLTNDK
RRHSSETFSAPTR
RSMVLDDDSPEIYK
RSNLFTSR
RSQFFEQGSSDSVAPDLPVPTLSAPSR
RSSEDLSTYASINFQK
RSSEDLSTYASINFQK
RSSEDLSTYASINFQK
RSSEDLSTYASINFQK
RTEITIVKPQESGLR
RTELSIDISSK
RTNAENEFVTIKK
RTPITVVR
RVEVPEALR
K
K
K
K
K
R
R
R
R
R
R
R
R
R
R
R
K
R
R
A
G
A
V
Q
A
A
A
K
W
Q
Q
Q
Q
R
Q
D
Q
39.4
47.2
74.9
45.2
60.2
50.2
28.5
47.8
38.3
35.4
73.2
75.3
34
39.5
40.1
49.4
39.5
40.3
55
31.1
30.4
29.5
28.1
28
28.1
29.6
29.4
26.5
29
30
30.1
30.2
29.8
23.2
26.8
27.8
19.4
23
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00555252,IPI00567177
IPI00421791
IPI00454476,IPI00780672
IPI00923716
35810
50196
62207
80911
Nedd4
Myh9
Myh9
Myh9
Rai14
Vim
Irs1
Nexn
Centg2
Lmo7
Irs1
Irs1
Irs1
Irs1
Sept9
9Sep
Krt1
Gsn
Lmod2
LOC682005;G
apdh;LOC685
186
Glyceraldehyde3phosphatedehydrogenase
Krt42
Keratin,typeIcytoskeletal42
Kb23
TypeIIkeratinKb23
Gsn
Isoform2ofGelsolin
9
3
8
28
12
5
8
41
51
19
49
122
34.80%
19.70%
11.40%
49.80%
RVIISAPSADAPMFVMGVNHEK
RVLDELTLAR
RYEEEVALR
RYIETDPANR
K
R
K
K
Y
A
A
D
45.6
58.3
55.3
29.6
29.2
23.7
28.2
28.6
2
2
2
2
86
4
12
7
11
46
8
9
13
104
4
12
7
11
58
11
9
13
217
11
15
16
39
181
13
16
13
50.30%
7.29%
10.90%
12.30%
5.14%
39.90%
30.10%
10.90%
17.30%
SAETEKEMATMKEEFQK
SAHENLMEAIR
SAILEASPK
SAIVHLINYQDDAELATR
SAIYQLEEEYENLLK
SALPFNR
SALSGHLETVMLGLLK
SASYSYLEER
SATLASIDAELQK
K
R
K
K
K
K
K
R
K
T
G
E
A
A
F
T
K
L
26.3
47.6
39.1
57
97.8
37.1
55.4
60.4
64.7
30.2
29.1
25.8
29.2
29.5
27.7
25.6
28
28
2
2
2
2
2
2
2
2
2
2
17
8
13
9
57
4
10
21
5
2
2
19
8
13
12
66
5
10
23
5
2
2
42
9
21
37
435
8
13
36
5
2
4.66%
29.70%
15.90%
14.80%
23.80%
39.20%
12.60%
12.80%
25.00%
7.95%
4.29%
SAVGFEYQGK
SDIDEIVLVGGSTR
SDIGEVILVGGMTR
SDIQDLLESVR
SDLEAQVESLK
SDLLLEGFNNYR
SDPDGYEFLEILK
SDPVVSYR
SEAQEEIGDLK
SEAQQPIYTKPLSPDAR
SEDILDYGPFK
Q
K
K
K
K
K
K
K
K
R
R
T
I
M
L
E
F
Q
E
R
T
D
40.5
70.6
58.8
70.4
73.4
55.8
39.4
37.4
75.9
49.7
38.2
27.5
28.2
27.7
29.3
28.4
28.9
29.5
26.8
28.3
28.6
28.7
2
2
2
2
2
2
2
2
2
2
2
5
18
68
7
19
19
6
28
78
9
24
24
7
165
99
82
596
596
8.44%
74.30%
43.10%
19.60%
24.00%
24.00%
SEDYVDIVQGNR
SEERAEVAESK
SEFKLEIDDLSSSVESVSK
SEIDHVKK
SEIDNVK
SEIDNVKK
R
R
K
R
R
R
V
C
S
Q
K
Q
36.1
49.1
27
34.5
31.1
48.2
28.9
28.6
29.4
24.6
27.2
27.3
2
2
2
2
2
2
Atp2a2
Krt17
Krt17
Krt10
Krt10
Anxa6
Tmpo
Dbn1
Specc1l
Myo1d
Ddx3x
Ppp1r12a
Actn4
Myh9
Hspa8
Ppp1r12b
Mybph
Myo1d
Ppp1r12a
Clip2
Cald1
Eprs
Lmo7
Myosin3
IPI00201578
223846
Leiomodin2
IPI00372026
61700
similartoRibosomebindingprotein1
IPI00188079
143655
Junctionplakoglobin
IPI00421429
81784
similartodesmoplakinisoformIisoform2
IPI00366081
332383
LMO7b
IPI00421345
156634
IsoformShortofAnnexinA2
IPI00325146
38662
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
Kinesin1heavychain
IPI00364904
109514
IPI00198498,IPI00198520,IPI00558156,I
CortactinisoformC
PI00777920
52664
78kDaglucoseregulatedprotein
IPI00206624
72331
Stress70protein,mitochondrial
IPI00363265
73840
CytospinA
IPI00372846
124324
TypeIhairkeratinKA27
IPI00551773
45954
234kDaprotein
IPI00391300
233603
Calsequestrin2
IPI00231901
49386
Elongationfactor2
IPI00203214
95268
CytospinA
IPI00372846
124324
similartoEpithelialproteinlostinneoplasm
IPI00373011
83779
Ribophorin1
IPI00204365
68384
Isoform2ofProcollagenlysine,2oxoglutarate5dioxygenase
2
IPI00208888,IPI00370551
86940
Isoform1ofTropomyosinbetachain
IPI00230775
32820
Myosin3
IPI00201578
223846
Keratin,typeIIcytoskeletal6A
IPI00393340
59233
Keratin,typeIIcytoskeletal5
IPI00382153
61809
Keratin,typeIIcytoskeletal5
IPI00382153
61809
IsoformSERCA2BofSarcoplasmic/endoplasmicreticulum
calciumATPase2
IPI00190020,IPI00231369
115376
Keratin,typeIcytoskeletal17
IPI00370073
48106
Keratin,typeIcytoskeletal17
IPI00370073
48106
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
56489
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
56489
AnnexinA6
IPI00421888,IPI00831745
75740
75kDaprotein
IPI00569391
74885
IsoformAofDrebrin
IPI00231407,IPI00231784
77453
CytospinA
IPI00372846
124324
MyosinId
IPI00207989
116081
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
Alphaactinin4
IPI00213463
104900
Myosin9
IPI00209113
226326
Heatshockcognate71kDaprotein
IPI00208205
70855
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
111371
53kDaprotein
IPI00557294
52762
MyosinId
IPI00207989
116081
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
111kDaprotein
IPI00476704
111364
Caldesmon
IPI00208118
60567
170kDaprotein
IPI00421357,IPI00476855
170072
LMO7b
IPI00421345
156634
5
20
20
13
13
2
2
4
11
42
7
9
26
123
19
5
3
52
9
22
12
9
46
5
27
27
22
22
2
2
5
11
50
7
9
29
194
23
5
3
69
9
24
14
9
58
7
386
386
362
244
2
2
7
19
166
10
16
46
2027
49
6
3
255
16
32
22
9
181
6.70%
43.40%
43.40%
21.50%
21.50%
2.82%
4.05%
9.34%
12.50%
46.10%
13.30%
10.90%
40.80%
52.30%
39.00%
8.86%
11.30%
53.00%
10.90%
22.20%
21.80%
7.99%
39.90%
SEIGIAMGSGTAVAK
SEISELR
SEISELRR
SEITELR
SEITELRR
SELDMLDIR
SELVANNVTLPAGEQR
SESEVEEAAAIIAQRPDNPR
SFDSASQVPNAAAAAIPR
SFHSFYQLLQGGSEQMLHSLHLQK
SFLLDLLNATGK
SFLSSTSTTAK
SFSTALYGESDL
SFVEK
SFYPEEVSSMVLTK
SGATALHVAAAK
SGDQDSILFIR
SGFILSVPGN
SGGTALHVAAAK
SGLLTETSSR
SGRYEMEETEVVITSYQK
SHMVVSDTLEDFQK
SHSPSMSQSGSQLR
K
K
K
K
K
R
K
K
K
R
R
K
K
K
K
R
R
R
K
R
R
K
R
T
R
T
R
T
E
K
E
T
S
D
T
V
M
G
S
G
Y
N
V
N
70.8
37
33.6
51
43.5
48.6
63.9
70.5
68.3
40.6
98.1
51.8
44.6
32.2
82.1
51.4
60
64.2
65.3
82.1
37.9
57.3
68.2
28.5
28
27.4
28
27.8
27.9
28.5
29.5
29.7
29.8
24.8
28
28.7
26.7
29.8
25.8
28.2
27.9
25.3
27.8
30.9
29.2
29.4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Lmo7
Copg
Tpm1
Tpm1
Rrbp1
Tra1
Copa
Ckap4
Hspa8
Kab
Aldh3a1
Thbs1
Lmod3
Actn4
Actn1
Hsp90ab1
Krt76
Krt77
Myo1d
Myo1c
Rai14
Myh3
Myh3
Tpm1
Mprip
Mprip
Lmod3
Ppp1r12b
Krt75
Krt77
Myh10
Myh11
Tpm2
Tpm2
Tpm1
Immt
Rai14
Aldh3a1
Ckap4
Flii
Nes
Nnt
Vcl
LMO7b
IPI00421345
Coatomersubunitgamma
IPI00780394
Isoform1ofTropomyosinalpha1chain
IPI00197888
tropomyosin1,alphaisoformc
IPI00210945
similartoRibosomebindingprotein1
IPI00188079
Isoform1ofEndoplasmin
IPI00365985
Copaprotein
IPI00372458
cytoskeletonassociatedprotein4
IPI00365982
Heatshockcognate71kDaprotein
IPI00208205
174kDaprotein
IPI00776774
Aldehydedehydrogenase,dimericNADPpreferring IPI00231064
Thrombospondin1
IPI00422076
similartoleiomodin3
IPI00568699
Alphaactinin4
IPI00213463
Alphaactinin1
IPI00209082,IPI00454431
HeatshockproteinHSP90beta
IPI00471584
TypeIIkeratinKb9
IPI00421812
Keratin,typeIIcytoskeletal1b
IPI00454475
MyosinId
IPI00207989
MyosinIc
IPI00393867
Isoform2ofAnkycorbin
IPI00372146
Myosin3
IPI00201578
Myosin3
IPI00201578
tropomyosin1,alphaisoformc
IPI00210945
258kDaprotein
IPI00392930
258kDaprotein
IPI00392930
similartoleiomodin3
IPI00568699
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
58kDaprotein
IPI00777617
Keratin,typeIIcytoskeletal1b
IPI00454475
234kDaprotein
IPI00391300
similartoMyosin11
IPI00558912
Isoform1ofTropomyosinbetachain
IPI00230775
Isoform1ofTropomyosinbetachain
IPI00230775
Isoform1ofTropomyosinalpha1chain
IPI00197888
82kDaprotein
IPI00364895,IPI00566985
Isoform2ofAnkycorbin
IPI00372146
Aldehydedehydrogenase,dimericNADPpreferring IPI00231064
cytoskeletonassociatedprotein4
IPI00365982
FlightlessIhomolog
IPI00211698
Isoform1ofNestin
IPI00194103
76kDaprotein
IPI00390435,IPI00555265
Vinculin
IPI00365286
46
9
3
33
12
3
15
8
19
8
5
19
3
26
22
15
2
3
52
50
34
69
86
33
40
40
10
3
2
2
58
2
18
18
3
6
29
5
11
8
16
2
6
58
9
5
59
12
3
15
8
23
8
5
20
3
29
26
15
2
3
69
65
39
76
104
59
54
54
10
3
2
2
67
2
28
24
4
7
33
5
11
8
17
2
6
181
10
17
252
15
3
21
11
49
12
10
38
8
46
34
32
6
5
255
289
69
172
217
252
117
117
16
3
3
3
363
2
165
98
37
7
50
10
17
9
27
2
7
39.90%
12.90%
65.50%
65.10%
10.90%
5.72%
13.60%
20.20%
39.00%
5.19%
12.40%
17.70%
9.40%
40.80%
41.70%
24.40%
8.43%
12.90%
53.00%
48.90%
39.20%
42.20%
50.30%
65.10%
19.90%
19.90%
25.80%
5.34%
10.10%
11.40%
40.00%
8.74%
74.30%
67.60%
68.30%
14.00%
36.00%
12.40%
25.70%
7.56%
10.50%
4.16%
7.88%
SHSPSMSQSGSQLR
SIATLAITTLLK
SIDDLEDELYAQK
SIDDLEEK
SIEALLEAGQAQDSQASR
SILFVPTSAPR
SILLSVPLLVVDNK
SINDNIAIFTDVQK
SINPDEAVAYGAAVQAAILSGDK
SIQSDAPVYLR
SISGALASDLGK
SITLFVQEDR
SITTLNIESNFITGK
SIVDYKPNLDLLEQQHQLIQEALIFDNK
SIVNYKPK
SIYYITGESK
SKAEAEALYQTK
SKDEAEALYQTK
SKDTCIMISGESGAGK
SKEPAYIR
SKEQEVTELVQK
SKLEQQVDDLESSLEQEK
SKLEQQVDDLESSLEQEKK
SKQLEDELVSLQK
SKSNPDFLK
SKSNPDFLKK
SLAAQEVPFGAR
SLDEEPIYHR
SLDLDSIIAEVK
SLDLDSIINAVR
SLEAEILQLQEELASSER
SLEAELMQLQEDLAAAER
SLEAQADK
SLEAQADKYSTK
SLEAQAEK
SLEDALNQTATVTR
SLEDATEYIHR
SLEEAIQFINQR
SLEETQLALSSDLK
SLEGTEAQVFK
SLEVEEEEQR
SLGAEPLEVDLK
SLGEIAALTSK
R
R
K
K
R
K
R
K
K
K
K
K
R
R
K
K
R
K
R
R
K
K
K
R
K
K
R
R
R
R
K
K
K
K
K
K
K
R
R
R
R
K
R
N
T
L
V
A
G
Q
R
S
R
N
A
G
H
I
E
L
Y
T
C
F
K
L
K
K
D
K
L
A
T
A
A
Y
E
Y
Q
A
E
G
A
I
E
L
62.5
75.5
102
48.2
75.6
49.9
64.4
90.6
87.6
49.7
71.9
64.3
83.5
22.2
30.7
52.7
78.5
58.5
36.2
34.8
69.6
53.1
69.7
94.2
31.4
29
67.2
32.5
112
70.7
94.9
33.7
48.3
76
63.9
70.7
61.8
61.2
95.9
63.6
43.9
46.2
59.3
28.3
14.1
29.5
27.6
29.9
25.8
15.7
29.2
29.4
28.1
28.3
27.7
26.7
25.8
23.6
27.7
29.1
29.2
29.3
26.6
27.8
30.2
29.5
27.4
27.4
28.7
28.3
28.5
27.5
27.7
28.8
30.9
26
29.1
27.1
28.7
28.3
28.2
28.2
29.3
28.7
26.3
27.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Myh3
Lmod2
Rrbp1
Jup
Dsp
Lmo7
Anxa2
Ppp1r12a
Kif5b
Cttn
Hspa5
Hspa9
Specc1l
Krt33a
Myh10
Casq2
Eef2
Specc1l
Lima1
Rpn1
Plod2
Tpm2
Myh3
LOC683313
Krt5
Krt5
156634
98515
32664
32831
143655
92756
138346
63529
70855
173996
50321
129653
57499
104900
102946
83266
61742
57238
116081
119797
105981
223846
223846
32831
257845
257845
57499
111371
57763
57238
233603
226689
32820
32820
32664
82231
105981
50321
63529
144843
208776
75804
116599
S10:Phospho(+79.97)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
S7:Phospho(+79.97)
M4:Oxidation(+15.99)
M3:Oxidation(+15.99)
M18:Oxidation(+15.99)
M3:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
S4:Phospho(+79.97)
T5:Phospho(+79.97)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M5:
Oxidation(+15.99)
M6:Oxidation(+15.99)
S9:Phospho(+79.97)
M5:Oxidation(+15.99)
M7:Oxidation(+15.99)
M11:Oxidation(+15.99)
M7:Oxidation(+15.99)
M6:Oxidation(+15.99)
M17:Oxidation(+15.99)
S7:Phospho(+79.97),M17:
Oxidation(+15.99)
M7:Oxidation(+15.99)
M6:Oxidation(+15.99)
775.8499
735.8635
636.3117
687.8646
459.7633
577.3193
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
S2:Phospho(+79.97)
S3:Phospho(+79.97)
S7:Phospho(+79.97)
M7:Oxidation(+15.99)
M5:Oxidation(+15.99)
M16:Oxidation(+15.99)
M10:Oxidation(+15.99)
M6:Oxidation(+15.99)
M3:Oxidation(+15.99)
M6:Oxidation(+15.99)
S3:Phospho(+79.97),M6:
Oxidation(+15.99)
T4:Phospho(+79.97)
S3:Phospho(+79.97)
S3:Phospho(+79.97)
S1:Phospho(+79.97)
2
2
2
2
2
2
4.43
0.19
2.53
3.93
2.43
1.98
334
334
227
2
483
517
348
348
238
13
492
526
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
502.2828
818.4161
406.7539
1,002.55
2,452.22
811.4922
1,003.56
2,453.23
812.4995
2
3
2
0.04
2.85
0.72
71
44
836
78
65
842
TRUE
TRUE
TRUE
3,714.97
960.5646
1,106.51
1,310.67
1,052.60
3,715.97
961.5725
1,107.51
1,311.67
1,053.61
4
2
2
2
2
3.07
0.02
0.03
3.66
0.08
95
561
373
841
671
130
569
381
851
680
TRUE
TRUE
TRUE
TRUE
TRUE
519.3076
614.3203
789.903
493.767
769.3666
637.8156
654.678
616.3359
841.9058
910.9423
497.6052
696.9987
653.332
571.8309
784.8897
1,554.90
1,226.63
1,577.79
985.5184
1,536.72
1,273.62
1,961.01
1,230.66
1,681.80
1,819.87
1,489.79
2,087.97
1,956.97
1,141.65
1,567.76
1,555.91
1,227.63
1,578.80
986.5271
1,537.72
1,274.62
1,962.01
1,231.66
1,682.80
1,820.87
1,490.80
2,088.98
1,957.98
1,142.65
1,568.77
3
2
2
2
2
2
3
2
2
2
3
3
3
2
2
0.13
0.57
0.57
0.83
0.58
3.77
4.93
0.47
3.07
3.57
1.99
0.31
1.42
0.46
0.41
89
502
23
831
566
755
2165
635
1882
81
1307
1699
48
799
108
103
513
40
839
579
764
2181
646
1896
97
1318
1717
68
808
121
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
623.8456
544.7716
727.3264
866.075
475.2413
865.97
638.3276
1,007.94
750.8593
506.2407
492.7553
649.827
479.7521
622.824
653.2954
736.3856
800.4307
655.3793
754.8751
494.2784
817.1043
465.7669
989.0007
670.7005
699.3622
751.3955
1,245.68
1,087.53
1,452.64
2,595.20
948.467
1,729.92
1,274.64
2,013.86
1,499.70
1,515.70
983.4949
1,297.64
957.4885
1,243.63
1,304.58
1,470.76
1,598.85
1,308.74
1,507.73
986.5411
2,448.29
929.5181
1,975.99
2,009.08
2,095.06
2,251.16
1,246.68
1,088.53
1,453.65
2,596.21
949.4744
1,730.93
1,275.64
2,014.87
1,500.71
1,516.70
984.5002
1,298.65
958.4959
1,244.64
1,305.58
1,471.76
1,599.85
1,309.75
1,508.74
987.5476
2,449.28
930.5261
1,976.99
2,010.09
2,096.06
2,252.16
2
2
2
3
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
3
2
2
3
3
3
0.23
1.61
0.03
1.91
0.43
1.86
3.19
1.47
1.65
2.20
2.52
0.50
0.36
1.21
0.40
3.59
0.33
1.99
3.02
1.34
6.05
0.22
0.27
0.83
3.92
3.11
809
208
482
149
386
2154
261
393
362
360
7
388
162
907
330
1359
1359
157
169
83
719
1478
112
969
1192
1192
818
217
494
170
392
2168
271
409
374
372
15
402
170
916
340
1371
1372
169
181
91
741
1485
129
986
1209
1210
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
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TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
838.0607
749.0326
744.3591
560.301
887.4699
608.8192
537.9199
561.936
490.7684
959.1492
963.4379
963.4399
642.6294
615.9725
576.3324
624.8444
517.2828
471.299
534.8123
M13:Oxidation(+15.99),M16:
Oxidation(+15.99)
801.0729
593.3532
582.8048
617.8142
M8:Oxidation(+15.99),M11:
Oxidation(+15.99)
683.6436
M7:Oxidation(+15.99)
643.8131
458.2625
677.0195
921.4664
402.7222
M11:Oxidation(+15.99)
562.3174
602.7781
673.8648
M12:Oxidation(+15.99)
1,550.69
1,470.72
1,271.61
1,374.72
918.5164
1,153.63
929.7512
481.2901
554.2612
656.343
527.3068
M4:Oxidation(+15.99)
M19:Oxidation(+15.99),M21:
Oxidation(+15.99)
695.5263
575.8024
400.7716
947.9956
M4:Oxidation(+15.99)
696.3434
S3:Phospho(+79.97)
728.3281
S4:Phospho(+79.97)
485.8847
T6:Phospho(+79.97)
485.8847
572.3225
467.2566
471.7551
924.4912
404.228
636.8485
511.2951
643.3599
408.2409
455.2573
565.3024
507.7884
443.7784
M2:Oxidation(+15.99)
579.7711
M3:Oxidation(+15.99)
729.6567
588.8231
826.9005
401.884
M10:Oxidation(+15.99)
787.4069
961.1809
559.3405
423.2406
S4:Phospho(+79.97)
M3:Oxidation(+15.99)
1,549.68
1,469.71
1,270.61
1,373.71
917.5109
1,152.62
IPI00194087
IPI00558912
IPI00197888
IPI00197888
IPI00230775
IPI00367479,IPI00558912
IPI00558912
IPI00421795
IPI00421795
IPI00765011,IPI00360356,IPI00189819
IPI00197888,IPI00210945,IPI00230775
IPI00197888,IPI00210945,IPI00230775
IPI00558912
IPI00370090,IPI00370073,IPI00421855
IPI00200792,IPI00421785
IPI00421855
IPI00421855
IPI00367479,IPI00558912
IPI00768956
IPI00197888
IPI00382153,IPI00393340,IPI00207038
Scin
Pabpc1
Tpm2
Tpm2
Specc1l
Col1a1
Fermt2
Krt1
Irs1
Lmo7
Myh3
Col1a1
Myo1d
Myh3
Smtn
Kif5b
Hsp90ab1
Lmod3
Pik3ca
Vim
Myh9
Kbtbd10
Pik3ca
Nexn
Tmod3
Tmod1
Dsp
Centg2
Specc1l
Rai14
Atp1a1
Lmo7
Mprip
Irs1
Irs1
Irs1
Mprip
Ddx3x
Lima1
Ppp1r12a
Smtn
Flot1
Myo1d
Dbn1
Eprs
Lmo7
Copb1
Eprs
Hspa5
Hspa8
Mprip
Mprip
Scin
Rai14
Hspa9
Tmpo
Kb15
Scinderin
Polyadenylatebindingprotein1
Isoform2ofTropomyosinbetachain
Isoform2ofTropomyosinbetachain
CytospinA
collagen,type1,alpha1
RCG61183,isoformCRA_b
Keratin,typeIIcytoskeletal1
Insulinreceptorsubstrate1
LMO7b
Myosin3
collagen,type1,alpha1
MyosinId
Myosin3
smoothelin
Kinesin1heavychain
HeatshockproteinHSP90beta
similartoleiomodin3
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
Vimentin
IPI00365568,IPI00391226
IPI00189074
IPI00187731
IPI00187731
IPI00372846
IPI00844828
IPI00362106
IPI00421857
IPI00199662
IPI00421345
IPI00201578
IPI00844828
IPI00207989
IPI00201578
IPI00361871,IPI00561311
IPI00364904
IPI00471584
IPI00568699
80184
70683
32941
32941
124324
137936
77861
64814
131160
156634
223846
137936
116081
223846
99862
109514
83266
57499
2
3
4
4
11
17
2
7
31
35
76
13
42
76
10
13
25
10
2
3
5
7
11
17
2
8
39
43
92
13
53
92
10
13
26
10
2
6
11
21
19
17
2
135
145
112
323
13
149
323
15
13
38
16
3.78%
8.18%
64.40%
53.20%
12.50%
20.90%
3.82%
11.20%
31.80%
30.80%
46.50%
14.40%
45.40%
46.50%
13.90%
17.30%
37.00%
25.80%
SLGGQAVQVR
SLGYAYVNFQQPADAER
SLIASEEEYSTK
SLIASEEEYSTKEDKYEEEIK
SLLDEHHISYVIDEDVK
SLLLQGSNEIELR
SLMEQDVKENEALLLR
SLNDKFASFIDKVR
SLNYIDLDLVK
SLSDVSAEDVQSLR
SLSELTTQK
SLSQQIENIR
SLSSYNYIR
SLSTELFK
SLSVLSPR
SLTEYLQNVEQK
SLTNDWEDHLAVK
SLVDYMYLQK
R
R
K
K
R
K
R
K
K
K
R
K
K
R
R
K
K
K
V
A
E
L
S
G
F
F
D
Q
S
S
V
L
Q
K
H
A
66.3
96.3
87.7
62.8
50.9
60.1
25.9
26.6
63.3
116
45.3
63.6
48.5
49.9
37.4
64.2
57.2
55.8
26.1
31.1
28.4
30.7
29.5
25.5
28.8
25.7
26
28.6
27
28.3
27.6
26.4
27.1
29.6
29
28.3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00769069,IPI00769166
IPI00230941
124233
53716
10
36
10
48
12
124
11.30%
74.00%
SLWVINSALR
SLYSSSPGGAYVTR
K
R
I
S
30.5
66.9
27.7
29.2
2
2
Myosin9
IPI00209113
KelchrepeatandBTBdomaincontainingprotein10 IPI00190417
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
Isoform1ofNexilin
IPI00209938
Tropomodulin3
IPI00373505
Tropomodulin1
IPI00189723,IPI00421889
similartodesmoplakinisoformIisoform2
IPI00366081
centaurin,gamma2
IPI00389524
CytospinA
IPI00372846
Isoform2ofAnkycorbin
IPI00372146
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
LMO7b
IPI00421345
258kDaprotein
IPI00392930
Insulinreceptorsubstrate1
IPI00199662
Insulinreceptorsubstrate1
IPI00199662
Insulinreceptorsubstrate1
IPI00199662
258kDaprotein
IPI00392930
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
similartoEpithelialproteinlostinneoplasm
IPI00373011
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
smoothelin
IPI00361871,IPI00561311
Isoform1ofFlotillin1
IPI00208784
MyosinId
IPI00207989
IsoformAofDrebrin
IPI00231407,IPI00231784
170kDaprotein
IPI00421357,IPI00476855
LMO7b
IPI00421345
Coatomersubunitbeta
IPI00211812
170kDaprotein
IPI00421357,IPI00476855
78kDaglucoseregulatedprotein
IPI00206624
Heatshockcognate71kDaprotein
IPI00208205
258kDaprotein
IPI00392930
258kDaprotein
IPI00392930
Scinderin
IPI00365568,IPI00391226
226326
68198
119
3
194
3
3095
4
51.60%
6.11%
SMEAEMIQLQEELAAAER
SMFGVAIHK
K
R
A
G
115
30.6
30.1
27.9
2
2
124233
78377
39455
40464
332383
96839
124324
105981
113040
156634
257845
131160
131160
131160
257845
73130
83779
115268
99862
47481
116081
77453
170072
156634
106996
170072
72331
70855
257845
257845
80184
15
15
6
5
18
5
21
29
9
46
29
31
33
30
35
11
5
8
10
3
42
6
9
44
14
9
19
18
35
33
2
17
20
7
6
18
6
23
35
9
58
33
42
45
40
51
11
6
9
10
3
51
7
9
55
14
9
20
22
51
42
2
28
49
8
8
28
11
36
51
11
181
58
126
88
85
95
20
11
9
13
3
135
15
9
141
15
9
52
56
95
71
3
18.40%
23.90%
21.90%
19.20%
7.79%
5.91%
25.00%
36.10%
12.10%
39.90%
15.80%
34.10%
36.00%
31.60%
18.00%
19.30%
7.95%
10.50%
13.70%
6.78%
46.20%
14.60%
7.99%
38.90%
20.80%
7.99%
33.50%
37.30%
18.00%
17.40%
3.78%
SMLLSSEQLK
SMVLDDDSPEIYK
SNDPVAAAFADMLK
SNDPVAFALAEMLK
SNKPIILR
SNLFTSR
SNYGEIPGQEHLLR
SPAESVDNLGK
SPDFTNENPLETR
SPDQFSDMR
SPEGTTVSGYDIMK
SPGEYVNIEFGSGQPGYLAGPATSR
SPGEYVNIEFGSGQPGYLAGPATSR
SPGEYVNIEFGSGQPGYLAGPATSR
SPGLLGTPDLK
SPILVATAVAAR
SPKPLSPSLR
SPLIESTANMENNQPQK
SPLSAEELMAIEDEGILDK
SPPVMVAGGR
SPQIFDDER
SPSDSSTASTPITEQIER
SPSNTGEYTSLYNK
SQFFEQGSSDSVAPDLPVPTLSAPSR
SQGMALSLGDK
SQGSGLSSGGAGEGQGPK
SQIFSTASDNQPTVTIK
SQIHDIVLVGGSTR
SQISSINSDIEALR
SQISSINSDIEALRR
SQLIVVEEGSEPPELMK
R
R
R
R
R
R
R
K
R
R
K
K
K
K
R
K
K
K
R
R
K
R
K
R
K
K
K
K
R
R
R
L
A
V
V
A
K
T
T
N
I
S
S
S
S
T
G
K
T
M
V
C
A
V
W
I
K
V
I
R
Q
V
41.6
83.7
72.5
80.5
33.7
43.7
47.5
74.2
57.4
59.2
77
92
57.6
65.1
65.9
112
36.5
95.5
115
30.9
73
94.4
70.8
82.7
40.5
80.6
94.6
67.2
98.3
42.3
72.3
29
29.4
28.9
29.2
19.4
26.9
29.2
28.7
29.8
25.2
29
31.3
31.2
30.8
23.4
20.5
22.8
30.3
30.1
26.7
27.5
30.8
29.4
30.5
27.7
29.4
29.1
26.2
28.4
28.1
29.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
IPI00372146
IPI00363265
IPI00569391
IPI00207038
105981
73840
74885
58080
43
13
6
2
50
13
6
2
62
23
6
27
48.90%
28.00%
12.70%
13.80%
SQMPQEAPDDSGDMKETMNR
SQVFSTAADGQTQVEIK
SQVISPPLAQAIR
SRAEAESWYQTK
K
K
R
R
M
V
E
Y
27.6
97.4
64.4
55.3
29.4
30.1
22.9
29.4
2
2
2
2
M16:Oxidation(+15.99)
M3:Oxidation(+15.99),M14:
Oxidation(+15.99),M18:
Oxidation(+15.99)
772.315
904.9561
690.405
728.3496
IPI00554334
IPI00373011
IPI00421345
IPI00421345
IPI00421345
IPI00421345
IPI00382153
IPI00199662
81251
83779
156634
156634
156634
156634
61809
131160
27
5
44
39
46
46
23
38
33
6
55
49
58
58
31
51
100
11
141
116
181
181
674
99
50.10%
7.95%
38.90%
32.70%
39.90%
39.90%
31.10%
40.60%
SREYDQLYEEYTR
SRPFTVAASFR
SRSTTELNDPLIEK
SRSTTELNDPLIEK
SRSTTELNDPLIEK
SRSTTELNDPLIEK
SRTEAESWYQTK
SRTESITATSPASMVGGKPGSFR
K
R
K
K
K
K
R
R
T
T
S
S
S
S
Y
V
32.7
39.1
38
68.2
38.2
38.2
48.2
76.9
29.8
26.6
29.7
29.7
29.7
29.7
28.9
29.8
2
2
2
2
2
2
2
2
584.6023
619.8358
561.6058
841.9044
561.6054
561.6054
743.3535
780.7293
33
4
31
31
30
4
15
2
44
4
5
9
29
8
44
5
6
45
4
42
42
42
4
15
2
55
4
5
9
35
9
53
5
6
88
5
126
126
108
4
21
2
144
5
7
10
51
12
78
5
6
36.00%
5.10%
34.10%
34.10%
29.50%
12.50%
13.60%
4.14%
47.80%
9.39%
6.50%
12.90%
36.10%
4.68%
37.80%
7.81%
12.70%
SRTESITATSPASMVGGKPGSFR
SSALVIQSYIR
SSEDLSTYASINFQK
SSEDLSTYASINFQK
SSEDLSTYASINFQK
SSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQR
SSGLTAVWVAR
SSGPTSLFAVTVAPPGAR
SSINDAAEFK
SSLQTMESDVYTEVR
SSNLQYFK
SSPEPVALTESETEYVIR
SSPPVEHPAGTSTADRDVIIQQLQDTLHDLQK
SSPVVIDASTAIDAPSNLR
SSSLSVTTDFSESLQSPYSESK
SSTIVEIFSK
SSTPLPTVSSSAENTR
R
K
R
R
R
R
R
K
K
K
R
K
K
R
K
K
R
V
G
Q
Q
Q
G
N
Q
V
E
R
C
R
F
E
Y
Q
47.2
70.6
84.9
84.9
84
63.6
63.3
36.8
70.1
99.3
39.8
107
21.3
91.3
78.1
45.3
88.5
30.9
26.2
28.9
28.9
29.5
26.4
27.1
27.2
28.2
30
25.5
30.1
28.2
27.3
31.2
26.5
29.4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Pik3r2
Lima1
Lmo7
Lmo7
Lmo7
Lmo7
Krt5
Irs1
Isoform2ofAnkycorbin
Stress70protein,mitochondrial
75kDaprotein
TypeIIkeratinKb15
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
similartoEpithelialproteinlostinneoplasm
LMO7b
LMO7b
LMO7b
LMO7b
Keratin,typeIIcytoskeletal5
Insulinreceptorsubstrate1
Irs1
Myo1b
Irs1
Irs1
Irs1
Htra1
Copa
Hnrnpu
Myo1d
Ckap4
Hip1
Copg
Rai14
Fn1
Lmo7
Lima1
Tmpo
Insulinreceptorsubstrate1
IsoformCofMyosinIb
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
HtrAserinepeptidase1,isoformCRA_a
Copaprotein
SP120
MyosinId
cytoskeletonassociatedprotein4
huntingtininteractingprotein1
Coatomersubunitgamma
Isoform2ofAnkycorbin
Isoform1ofFibronectin
LMO7b
similartoEpithelialproteinlostinneoplasm
75kDaprotein
Mtdh
IPI00199662
131160
IPI00231045,IPI00331979,IPI00391496 124908
IPI00199662
131160
IPI00199662
131160
IPI00199662
131160
IPI00199325
51312
IPI00372458
138346
IPI00210090,IPI00566967
87731
IPI00207989
116081
IPI00365982
63529
IPI00765689
114988
IPI00780394
98515
IPI00372146
105981
IPI00200757,IPI00231982,IPI00231983 272486
IPI00421345
156634
IPI00373011
83779
IPI00569391
74885
IPI00210319,IPI00389749,IPI00389750,I
Isoform1ofDynamin2
PI00896218
98232
Heatshockcognate71kDaprotein
IPI00208205
70855
programmedcelldeath6interactingprotein
IPI00607140,IPI00767837
95867
Isoform1ofNexilin
IPI00209938
78377
IPI00202027,IPI00203088,IPI00464512,I
Isoform1ofHeterogeneousnuclearribonucleoproteinHPI00851133,IPI00851145
49171
SerpinH1
IPI00204703
46501
CytospinA
IPI00372846
124324
septin9isoform1
IPI00215235,IPI00782707
64850
Alphaactinin4
IPI00213463
104900
258kDaprotein
IPI00392930
257845
Stress70protein,mitochondrial
IPI00363265
73840
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
LMO7b
IPI00421345
156634
Elongationfactor1alpha1
IPI00195372,IPI00551729
50096
Vinculin
IPI00365286
116599
Clathrinheavychain1
IPI00193983
191585
Myosin9
IPI00209113
226326
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
Clathrinheavychain1
IPI00193983
191585
Generalvesiculartransportfactorp115
IPI00324618
107147
similartodesmoplakinisoformIisoform2
IPI00366081
332383
Insulinreceptorsubstrate1
IPI00199662
131160
Insulinreceptorsubstrate1
IPI00199662
131160
Nucleolin
IPI00231827,IPI00882501
77259
Rhoguaninenucleotideexchangefactor2
IPI00368617
111895
Insulinreceptorsubstrate1
IPI00199662
131160
Insulinreceptorsubstrate1
IPI00199662
131160
LMO7b
IPI00421345
156634
75kDaprotein
IPI00569391
74885
Actin,alphaskeletalmuscle
IPI00189813
42034
proteinphosphatase1,regulatory(inhibitor)subunit12B IPI00371976
111371
Myosin3
IPI00201578
223846
MyosinId
IPI00207989
116081
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
IsoformShortofAnnexinA2
IPI00325146
38662
Isoform1ofFibronectin
IPI00200757,IPI00231982,IPI00231983 272486
LMO7b
IPI00421345
156634
Vimentin
IPI00230941
53716
Keratin,typeIIcytoskeletal6A
IPI00393340
59233
Keratin,typeIIcytoskeletal6A
IPI00393340
59233
TypeIIkeratinKb15
IPI00207038
58080
Scinderin
IPI00365568,IPI00391226
80184
similartokinectin1
IPI00563574
151567
Isoform2ofAnkycorbin
IPI00372146
105981
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
smoothelin
IPI00361871,IPI00561311
99862
Copaprotein
IPI00372458
138346
Isoform2ofGelsolin
IPI00923716
80911
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
83516
cytoskeletonassociatedprotein4
IPI00365982
63529
Tcomplexprotein1subunitgamma
IPI00372388
60630
Myosin3
IPI00201578
223846
Vinculin
IPI00365286
116599
Isoform1ofEndoplasmin
IPI00365985
92756
IsoformShortofAnnexinA2
IPI00325146
38662
IsoformShortofAnnexinA2
IPI00325146
38662
Myosin9
IPI00209113
226326
Hnrpkprotein
IPI00194974,IPI00780608
51012
Keratin,typeIIcytoskeletal5
IPI00382153
61809
Keratin,typeIcytoskeletal42
IPI00421791
50196
Myosin9
IPI00209113
226326
234kDaprotein
IPI00391300
233603
IPI00209277,IPI00515783,IPI00515808,I
Isoform1ofProteinLYRIC
PI00515819
63953
Myh9
Myh9
Myosin9
Myosin9
Dnm2
Hspa8
Pdcd6ip
Nexn
Hnrph1
Serpinh1
Specc1l
9Sep
Actn4
Mprip
Hspa9
Ppp1r12a
Lmo7
Lmo7
Lmo7
Lmo7
Eef1a1
Vcl
Cltc
Myh9
Cand1
Cltc
Uso1
Dsp
Irs1
Irs1
Ncl
Arhgef2
Irs1
Irs1
Lmo7
Tmpo
Acta1
Ppp1r12b
Myh3
Myo1d
Ppp1r12a
Anxa2
Fn1
Lmo7
Vim
LOC683313
LOC683313
Kb15
Scin
Ktn1
Rai14
Pik3r2
Smtn
Copa
Gsn
Pik3r2
Pik3r1
Ckap4
Cct3
Myh3
Vcl
Tra1
Anxa2
Anxa2
Myh9
Hnrnpk
Krt5
Krt42
Myh9
Myh10
IPI00209113
IPI00209113
2.92
0.70
0.82
3.21
587
469
364
326
606
485
376
337
TRUE
TRUE
TRUE
FALSE
M14:Oxidation(+15.99)
S10:Phospho(+79.97),M14:
Oxidation(+15.99)
807.385
618.8519
S1:Phospho(+79.97)
885.3864
S2:Phospho(+79.97)
885.3864
845.4038
1,160.28
573.8184
857.9617
541.2634
M6:Oxidation(+15.99)
880.9075
493.7511
1,004.01
874.9503
957.0057
1,183.56
555.8065
817.4063
3
2
3
2
3
3
2
3
2.04
0.66
0.75
0.39
0.17
0.17
1.26
4.35
451
587
1140
1140
1140
1140
349
298
463
597
1153
1153
1153
1153
360
320
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2,419.13
1,235.69
1,768.76
1,768.76
1,688.79
3,477.82
1,145.62
1,713.91
1,080.51
1,759.80
985.4866
2,006.00
3,495.77
1,912.00
2,365.10
1,109.60
1,632.80
2,420.13
1,236.70
1,769.76
1,769.76
1,689.80
3,478.82
1,146.63
1,714.91
1,081.52
1,760.80
986.4947
2,006.99
3,496.77
1,913.00
2,366.09
1,110.60
1,633.80
3
2
2
2
2
3
2
2
2
2
2
2
4
2
2
2
2
4.61
0.72
0.92
0.92
1.54
1.52
1.52
1.52
2.07
3.49
0.27
5.55
3.05
2.96
6.98
0.47
0.84
298
752
1215
1215
1215
270
413
180
239
292
276
641
382
1982
840
31
157
320
762
1229
1229
1229
302
423
197
248
306
283
658
413
2000
861
40
172
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
40.6
62.6
58.3
66.3
28.2
29.2
25.7
27.9
2
2
2
2
554.2954
846.3676
943.5203
505.7438
1,106.58
1,690.72
1,885.02
1,009.47
1,107.58
1,691.73
1,886.02
1,010.48
2
2
2
2
2.79
0.60
4.81
0.22
45
221
421
229
54
236
438
236
TRUE
TRUE
TRUE
TRUE
59.6
69.9
66.2
45.3
40
43.5
80.5
88.6
46
46
37
62.6
49.7
56.7
81.7
39.4
74.4
45.6
50.6
100
70.8
21.2
47
33.6
61.2
73.6
92.3
28.1
110
60.6
74.7
58
55.7
37.5
35.8
39.3
38
70.6
75.8
67.3
43.5
63.5
54.4
30.1
28.5
28.4
23.1
27.5
27.6
30.4
29.6
29.1
29.1
29.4
28.4
28.2
28.3
25
23.5
28.9
30.3
28
27.8
24.6
22.8
27.6
29.6
29.2
28.5
30
27.9
29.5
26.5
27.9
27.6
30.3
29.4
29.1
27.3
27
28.9
27.6
27.5
27
29.9
27.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
921.4542
752.3821
583.2794
518.8066
580.2902
598.2763
1,028.49
810.4116
720.3386
720.3386
720.3402
680.3544
560.8041
559.807
717.4063
421.2254
811.4224
785.7246
758.4017
928.9915
711.908
526.9747
573.7878
705.6912
757.853
717.8712
909.4219
674.0241
895.9501
535.2893
756.8967
487.7571
898.4273
738.8402
772.39
471.2326
457.7331
611.8204
675.8674
610.8303
487.7514
778.3738
465.2643
1,840.89
1,502.75
1,164.54
1,035.60
1,158.56
1,194.54
2,054.96
1,618.81
1,438.66
1,438.66
1,438.66
1,358.69
1,119.59
1,117.60
1,432.80
840.4352
1,620.83
2,354.15
1,514.79
1,855.97
1,421.80
1,577.90
1,145.56
2,114.05
1,513.69
1,433.73
1,816.83
2,019.05
1,789.88
1,068.56
1,511.78
973.4986
1,794.84
1,475.66
1,542.76
940.4496
913.4506
1,221.63
1,349.72
1,219.65
973.4872
1,554.73
928.513
1,841.89
1,503.75
1,165.55
1,036.60
1,159.57
1,195.54
2,055.96
1,619.81
1,439.67
1,439.67
1,439.67
1,359.70
1,120.60
1,118.61
1,433.80
841.442
1,621.83
2,355.15
1,515.79
1,856.97
1,422.81
1,578.91
1,146.57
2,115.05
1,514.70
1,434.73
1,817.83
2,020.05
1,790.89
1,069.57
1,512.79
974.5059
1,795.85
1,476.67
1,543.76
941.4581
914.4582
1,222.63
1,350.73
1,220.65
974.4948
1,555.74
929.521
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
3
2
2
2
3
2
3
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
4.53
3.11
1.12
0.98
1.40
2.58
0.37
1.46
1.47
1.47
3.76
0.12
0.03
0.36
2.92
1.28
2.73
4.84
3.33
1.80
0.88
0.33
0.29
5.04
1.59
0.20
0.83
3.22
0.05
2.32
0.43
0.54
0.22
3.08
5.01
0.67
0.24
0.83
0.03
0.13
0.23
2.93
0.09
151
46
1087
303
575
207
266
696
1142
1142
1142
1142
21
656
469
1520
859
1462
828
718
635
635
463
149
439
439
290
570
241
491
283
738
669
234
1957
365
29
250
250
239
312
510
55
167
59
1096
311
584
215
284
710
1153
1153
1153
1153
30
666
481
1526
873
1481
842
734
647
648
472
168
452
452
305
589
256
499
294
745
683
245
1970
372
36
260
261
249
319
523
63
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
8
7
15
28
8
7
15
41
12
7
21
122
17.20%
9.88%
13.60%
49.80%
TAIEAFNETIK
TALASPTPTR
TALNLFFK
TASDFISK
R
R
R
K
I
L
L
M
64.5
40.1
32.6
50
27.8
25.7
24.5
27
2
2
2
2
618.8279
507.7832
477.2784
434.7253
1,235.64
1,013.55
952.5412
867.435
1,236.65
1,014.56
953.5461
868.4417
2
2
2
2
0.33
0.22
3.11
1.31
473
353
1107
310
483
362
1114
317
TRUE
TRUE
TRUE
TRUE
27
33
100
50.10%
TATGFGFAEPYNLYGSLK
R
E
62.5
29.9
2
10
8
2
86
17
9
8
7
119
3
22
4
105
70
11
8
2
104
18
9
11
8
194
3
28
5
175
82
19
11
3
217
25
9
13
10
3095
3
602
18
2139
145
17.10%
20.20%
4.04%
50.30%
20.40%
16.70%
30.10%
33.30%
51.60%
10.10%
30.00%
20.80%
47.80%
45.50%
TATGYGFAEPYNLYSSLK
TAVDSLVAYSVK
TAVETAVLLLR
TAYLMGLNSSDLLK
TDAGFTLR
TDDEVVQREEEAIQLDGLNASQIR
TDLEKDIISDTSGEFR
TDLEKDIISDTSGEFRK
TDLLLEPYNK
TDYNASVSVPDSSGPER
TEAESWYQTK
TEITELRR
TELEDTLDSTAAQQELR
TELEDTLDTTAAQQELR
K
R
K
K
R
R
K
K
K
R
R
R
K
K
E
I
I
A
W
E
K
L
Y
I
Y
S
S
T
54.7
58.9
75.5
78.8
43
24
61.3
44.5
75.4
61.9
70.5
32.3
103
79.8
30.1
26.6
21.8
28.7
26.1
29.8
29.8
29.3
28
29.6
28.5
27
29.8
30
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
3.96%
TELGLDLGLEPK
R
R
41.8
26
2
226326
226326
123
132
194
196
2027
883
52.30%
55.20%
TEMEDLMSSK
TEMEDLMSSK
R
R
D
D
74.8
40.5
26.1
27.2
2
2
51.90%
11.50%
8.89%
31.30%
40.60%
TEMEDLMSSKDDVGK
TENELLR
TEPTAQQNLALQLAEK
TESITATSPASMVGGK
TESITATSPASMVGGKPGSFR
R
R
R
R
R
S
M
L
P
V
59.2
36.1
81.7
80.3
77.5
29.5
27.1
27.6
29.6
29.4
2
2
2
2
2
29.50%
TESITATSPASMVGGKPGSFR
R
V
26.6
30.8
2
Irs1
Hspa5
Mprip
Myh10
Myh9
Lmod2
Myo1c
Kif5b
Atp5a1
Gsn
Pdia6
30
19
40
55
138
3
47
2
4
17
4
42
20
51
59
222
3
62
2
4
22
4
108
36
83
166
3511
3
175
2
6
86
5
29.50%
33.90%
21.50%
38.10%
55.70%
11.70%
46.60%
2.39%
9.58%
33.80%
13.30%
TESITATSPASMVGGKPGSFR
TFAPEEISAMVLTK
TFDWAEFRPIQQALAQER
TFHIFYQLLSGAGEHLK
TFHIFYYLLSGAGEHLK
TFSLANTHADDAAAIAIAEMLK
TFTWLVR
TGAEGAVLDEAK
TGAIVDVPVGDELLGR
TGALELLK
TGEAIVDAALSALR
R
K
K
R
R
K
R
K
R
K
R
V
M
A
S
T
V
K
N
V
V
Q
35.5
109
33.1
48.2
97.2
31.7
52.6
67.4
73.9
59.8
94.3
30.8
28.6
29.5
27.8
27.7
29.8
25.8
27.7
26.5
25.5
27.2
2
2
2
2
2
2
2
2
2
2
2
11
57
9
3
17
13
11
66
9
3
17
13
12
435
9
3
17
13
19.00%
39.20%
16.40%
12.40%
20.90%
12.60%
TGGSEVVVTNK
TGLEDPER
TGLEQGNDAGYLAESEK
TGPAATTLSDTAAAESLVDSSEVTVIGFFK
TGPPGPAGQDGRPGPAGPPGAR
TGPPGPSGITGPPGPPGAAGK
K
R
K
R
K
R
N
Y
F
D
G
E
52.4
41.2
61.5
83.3
31.6
87.3
28.2
26
30.1
28
29.2
28.1
2
2
2
2
2
2
5
8
8
15
5
8
8
15
6
12
11
21
6.54%
9.69%
18.10%
13.60%
TGQLFHIDFGHILGNFK
TGSYGALAEITASK
TGTAEMSSILEER
TGVQTFR
K
K
K
R
S
E
I
R
38
85.7
85.6
32.9
27.5
28
29.3
24.9
2
2
2
2
3
30
138
132
10
33
38
33
29
3
33
222
196
12
45
51
45
39
3
42
3511
883
27
88
99
88
105
5.78%
33.70%
55.70%
55.20%
24.50%
36.00%
40.60%
36.00%
31.90%
TGYTLDVTTGQR
THDASGQLVHISQELLR
THEAQIQEMR
THEAQIQEMR
THINIVVIGHVDSGK
THSAGTSPTISHQK
THSAGTSPTISHQK
THSAGTSPTISHQK
THSAGTSPTISHQK
R
K
K
K
K
R
R
R
R
K
K
Q
Q
S
T
T
T
T
58.4
36.2
65.5
45.8
46.6
55.8
64
54
70.2
29.2
28
28.8
28.6
26.3
29.7
29.3
29.7
29.5
2
2
2
2
2
2
2
2
2
3
5
17
4
9
4
5
11
12
13
52
42
3
6
28
7
12
4
5
13
12
17
69
50
3
8
167
21
37
4
6
47
15
28
255
166
12.50%
14.00%
65.80%
53.20%
23.80%
7.08%
6.60%
34.60%
10.90%
30.80%
53.00%
46.10%
TIALNQVEDVR
TIAMDGTEGLVR
TIDDLEDEVYAQK
TIDDLEETLASAK
TIEELQQK
TIEYLEEVAVNFAK
TIGEELLPR
TIGGGDDSFNTFFSETGAGK
TILAETEGMLK
TINEVENQILTR
TIPASDLPQVR
TIPLYNLTGLSVSNGK
K
R
K
K
R
R
K
K
R
R
K
K
T
G
M
E
I
G
G
H
D
D
A
D
37.3
52.5
87.7
92.7
46.2
55.3
38.7
113
51.1
69.4
74.3
87.2
27.3
28.7
29.6
28.3
27.2
28.2
23
30.4
27.5
27.4
25.4
25.6
2
2
2
2
2
2
2
2
2
2
2
2
3
2
19
29
21
22
3
2
20
33
23
33
22
4
38
50
36
468
21.80%
15.00%
17.70%
36.00%
25.00%
41.10%
TITLEVEPSDTIENVK
TIVEEVQDGK
TIVTTLQDSIR
TKAEESLSDMR
TKDVEILHLR
TKFETEQALR
K
R
R
R
K
R
A
V
K
S
N
M
74.3
53.6
58.8
52.3
34.9
50.8
28.3
28.4
26
28.7
23.4
28.3
2
2
2
2
2
2
26
21
76
2
4
30
27
92
3
5
71
59
323
22
10
47.90%
39.60%
46.50%
21.20%
12.30%
TKLEQDLR
TKPYIQVDIGGGQTK
TKYETDAIQR
TKYETELNLR
TKYETEVSLR
R
K
R
R
R
A
T
T
M
Q
39.7
34.4
61.6
53.4
50.6
27.3
27.1
29
27.7
27.5
11
15
111
12
47
9
16
18
4
43
47
42
2
37
3
2
8
2
8
14
12
15
172
12
50
9
17
18
5
59
62
51
2
49
3
2
8
2
8
14
26
21
2414
12
182
10
27
28
5
215
175
135
2
105
3
3
12
4
8
15
12.00%
13.60%
50.00%
12.40%
31.50%
12.90%
10.50%
7.79%
15.00%
45.00%
46.60%
46.20%
4.18%
19.50%
9.08%
11.40%
5.19%
14.20%
7.10%
20.80%
TLALDKTEQEALEYFTK
TLDLPIYVTR
TLEDEAK
TLEDPDLNVR
TLEDQLSEAR
TLEEAVGNIVK
TLEEQNQLLSAELGGLR
TLELQGLINDLQR
TLENELDELDPDNALLPAGLR
TLFATEDSLEVR
TLFATEDSLEVRR
TLFTLEELR
TLHVEEVVPSVIEPSFGLGR
TLLTGEGGGESTGLPLTQGK
TLNDELEIIEGMK
TLNNKFASFIDKVR
TLPQLPNEEK
TLQGLEIELQSQLSMK
TLQIFNIEMK
TLQLALDLVSSR
K
R
K
K
R
K
K
R
R
K
K
R
K
R
K
K
R
R
K
K
Q
V
T
R
G
F
A
E
Q
R
Q
A
I
D
F
F
A
A
S
N
34.6
34.6
31.4
37.1
69.7
55.7
98.4
77.3
122
85.3
26.2
62.4
41.7
91.1
39.2
55.6
32.8
125
38.1
65.7
3
3
12
7
6
86
3
3
12
7
6
104
21
3
16
10
17
217
21.80%
15.80%
20.30%
12.90%
10.50%
50.30%
TLSDYNIQK
TLTIVDTGIGMTK
TLTLVDTGIGMTK
TLVLSNLSYSATEETLQEVFEK
TLVTQNSGVEALIHAILR
TLVVKPEDVYAMNPPK
R
R
R
K
K
R
E
A
A
A
A
F
49
89.8
89.8
30.8
38.3
42.7
Hist4h4
Insulinreceptorsubstrate1
IPI00199662
131160
78kDaglucoseregulatedprotein
IPI00206624
72331
258kDaprotein
IPI00392930
257845
234kDaprotein
IPI00391300
233603
Myosin9
IPI00209113
226326
Leiomodin2
IPI00372026
61700
MyosinIc
IPI00393867
119797
Kinesin1heavychain
IPI00364904
109514
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
Isoform2ofGelsolin
IPI00923716
80911
proteindisulfideisomeraseassociated6
IPI00365929
48743
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
IPI00876592
102739
234kDaprotein
IPI00391300
233603
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Proteindisulfideisomerase
IPI00198887
56935
collagen,type1,alpha1
IPI00844828
137936
Collagenalpha2(I)chain
IPI00188921
129547
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
IPI00208989
122595
Isoform1ofProteinphosphatase1regulatorysubunit12A IPI00400680,IPI00400681
115268
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
59737
Copaprotein
IPI00372458
138346
IPI00557424,IPI00764064,IPI00776515,I
70kDaprotein
PI00782066
69603
111kDaprotein
IPI00476704
111364
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
Elongationfactor1alpha1
IPI00195372,IPI00551729
50096
Insulinreceptorsubstrate1
IPI00199662
131160
Insulinreceptorsubstrate1
IPI00199662
131160
Insulinreceptorsubstrate1
IPI00199662
131160
Insulinreceptorsubstrate1
IPI00199662
131160
similartotranslocaseofinnermitochondrialmembrane50
homologisoform2
IPI00766169
39838
ATPsynthasesubunitbeta,mitochondrial
IPI00551812
56336
Isoform1ofTropomyosinbetachain
IPI00230775
32820
Isoform2ofTropomyosinbetachain
IPI00187731
32941
TypeIhairkeratinKA27
IPI00551773
45954
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
huntingtininteractingprotein1
IPI00765689
114988
Tubulinalpha1Bchain
IPI00339167
50134
similartoRibosomebindingprotein1
IPI00188079
143655
Alphaactinin1
IPI00209082,IPI00454431
102946
MyosinId
IPI00207989
116081
MyosinId
IPI00207989
116081
IPI00190240,IPI00198550,IPI00361888,I
PI00391830,IPI00476033,IPI00656453,I
PI00776427,IPI00882520
17934
RibosomalproteinS27a
Keratin,typeIcytoskeletal42
IPI00421791
50196
Thrombospondin1
IPI00422076
129653
Isoform2ofAnkycorbin
IPI00372146
105981
CytospinA
IPI00372846
124324
Keratin,typeIcytoskeletal17
IPI00370073
48106
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
78kDaglucoseregulatedprotein
IPI00206624
72331
Myosin3
IPI00201578
223846
Keratin,typeIcytoskeletal42
IPI00421791
50196
TypeIhairkeratinKA30
IPI00421797
50657
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00769069,IPI00769166
124233
Copaprotein
IPI00372458
138346
Myosin9
IPI00209113
226326
CullinassociatedNEDD8dissociatedprotein1
IPI00205466
136349
Myosin3
IPI00201578
223846
Coatomersubunitgamma
IPI00780394
98515
Isoform1ofNestin
IPI00194103
208776
similartodesmoplakinisoformIisoform2
IPI00366081
332383
Tropomodulin1
IPI00189723,IPI00421889
40464
MyosinIc
IPI00393867
119797
MyosinIc
IPI00393867
119797
MyosinId
IPI00207989
116081
similartoglycyltRNAsynthetase
IPI00364262,IPI00766072
88083
258kDaprotein
IPI00392930
257845
60kDaheatshockprotein,mitochondrial
IPI00339148
60939
Keratin,typeIIcytoskeletal1b
IPI00454475
57238
174kDaprotein
IPI00776774
173996
Keratin,typeIcytoskeletal13
IPI00421795
47713
Clathrinheavychain1
IPI00193983
191585
Coatomersubunitbeta
IPI00211812
106996
IPI00190240,IPI00198550,IPI00361888,I
PI00391830,IPI00476033,IPI00656453,I
PI00776427,IPI00882520
17934
RibosomalproteinS27a
HeatshockproteinHSP90alpha
IPI00210566
84800
HeatshockproteinHSP90beta
IPI00471584
83266
Nucleolin
IPI00231827,IPI00882501
77259
Junctionplakoglobin
IPI00421429
81784
Myosin3
IPI00201578
223846
IPI00231340,IPI00364897,IPI00368659,I
PI00559188,IPI00561052,IPI00561706,I
PI00764726,IPI00778180
11464
HistoneH4
3
3
4
24.00%
TLYGFGG
R
32.1
24.1
2
Krt17
Pdcd6ip
Keratin,typeIcytoskeletal17
programmedcelldeath6interactingprotein
IPI00370073
IPI00607140,IPI00767837
48106
95867
15
2
18
2
43
2
34.40%
3.46%
TMQALEIELQSQLSMK
TMQGSEVVNVLK
R
K
A
S
92.4
52.1
29.3
28.4
2
2
Krt14
Copb2
Krt1
Krt1
Vim
Anxa2
Anxa1
Anxa2
Myh3
Gsn
Specc1l
Specc1l
Gsn
Keratin,typeIcytoskeletal14
Coatomersubunitbeta'
Keratin,typeIIcytoskeletal1
Keratin,typeIIcytoskeletal1
Vimentin
IsoformShortofAnnexinA2
AnnexinA1
IsoformShortofAnnexinA2
Myosin3
Isoform2ofGelsolin
CytospinA
CytospinA
Isoform2ofGelsolin
IPI00421855
IPI00231953
IPI00421857
IPI00421857
IPI00230941
IPI00325146
IPI00231615,IPI00777179
IPI00325146
IPI00201578
IPI00923716
IPI00372846
IPI00372846
IPI00923716
52667
102535
64814
64814
53716
38662
38813
38662
223846
80911
124324
124324
80911
6
11
6
8
38
3
2
3
68
18
14
14
14
10
11
7
13
51
3
2
3
78
23
16
16
17
171
12
130
278
155
6
2
3
99
100
20
20
63
24.70%
15.90%
10.40%
12.20%
77.50%
9.14%
9.25%
10.30%
43.10%
37.20%
16.30%
16.30%
31.60%
TMQNLEIELQSQLSMK
TMYLLGYIPK
TNAENEFVTIK
TNAENEFVTIKK
TNEKVELQELNDR
TNQELQEINR
TPAQFDADELR
TPAQYDASELK
TPGAMEHSLVLHQLR
TPITVVR
TPLSPSPMK
TPPAAAVSPMQR
TPSAAYLWVGTGASDAEK
R
R
R
R
R
R
K
K
K
R
R
K
K
A
D
K
D
F
V
A
A
C
Q
T
H
T
122
38
73.4
76.4
80.6
65.9
67.4
67.5
74.9
31
39.2
53.2
110
30
27.9
28.9
28
29.2
28.4
28.4
28.4
28.5
23.1
27.8
28.4
29.5
2
2
2
2
2
2
2
2
2
2
2
2
2
PreBcellleukemiatranscriptionfactorinteractingprotein1 IPI00201858
ATPsynthasesubunitalpha,mitochondrial
IPI00396910
Clathrinheavychain1
IPI00193983
LMO7b
IPI00421345
82kDaprotein
IPI00364895,IPI00566985
3
2
2
2
1,751.79
1,238.66
1,682.80
1,682.80
1,682.80
1,682.80
1,485.70
2,340.16
D
M
E
Q
108
Pbxip1
Atp5a1
Cltc
Lmo7
Immt
2,314.92
1,808.90
1,379.80
1,455.69
1,750.78
1,237.66
1,681.79
1,681.79
1,681.79
1,681.79
1,484.69
2,339.16
A
D
T
S
E
A
H
T
S
S
S
S
C
T
A
S
S
T
T
D
R
H
G
Q
G
G
L
S
F
R
K
R
K
K
I
K
T
K
D
K
M
F
G
2067
6
6
93
99
Pik3r1
Kb23
Krt42
Arbp
Myo1c
2,313.92
1,807.90
1,378.79
1,454.68
R
R
K
K
K
K
K
R
R
R
R
R
K
K
K
K
K
K
K
K
K
K
R
K
R
R
R
R
K
R
R
K
R
K
R
K
R
R
R
R
K
R
K
42
Pik3r2
Myh9
Kif5b
Mprip
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
K
K
K
K
194
5
6
39
51
Insulinreceptorsubstrate1
IPI00199662
Leiomodin2
IPI00372026
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
Myosin9
IPI00209113
Kinesin1heavychain
IPI00364904
258kDaprotein
IPI00392930
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
TypeIIkeratinKb23
IPI00454476,IPI00780672
Keratin,typeIcytoskeletal42
IPI00421791
60SacidicribosomalproteinP0
IPI00200147
MyosinIc
IPI00393867
TRUE
TRUE
240
342
252
249
471
397
920
120
240
735
2226
915
915
915
596
503
612
315
595
28
605
400
831
915
943
1011
464
342
2042
2043
222
SSVLENFVGR
STAGDTHLGGEDFDNR
STAVVEQGGIQTVDQLIK
STFEELER
30
Pik3r2
TRUE
TRUE
1695
494
231
330
239
236
464
391
907
110
228
727
2213
891
891
891
586
492
603
299
577
19
597
383
818
890
933
994
448
329
2029
2029
206
STGEAFVQFASQEIAEK
STGLAFSLYQAMAK
STLDINEMAR
STLINTLFK
STLPDADRER
STLWQEEMR
STNGDTFLGGEDFDQALLR
STQGVTLTDLQEAEK
STTELNDPLIEK
STTELNDPLIEK
STTELNDPLIEK
STTELNDPLIEK
STTTGHLIYK
STVEGIQASVK
SVDPTLALSVYLR
SVHELEK
SVILEAFSSPSEEVK
SVNESLNNLFITEEDYQALR
SVPVEGESELVTAAK
SVQNDSQALAEVLNQLK
SVSAPQQIINPIR
SVSAPQQIINPIRR
SVSLYYTGEK
SVSTTNIAGHFNDESPLGLR
SVTPDSLGHTPPAR
SVTPDSLGHTPPAR
SWASPVYTETEGTFSR
SYEAAASALQIAAHTAFVAK
SYELPDGQVITIGNER
SYFSTLVPR
SYHIFYQILSNK
SYIHEVAR
SYLTPVRDEESESQR
SYSPYDMLESIR
SYTITGLQPGTDYK
SYTSDLQK
SYVTTSTR
TAAENEFVTLK
TAAENEFVTLKK
TAAENEFVVLK
TAEEFLHK
TAEHEAAQQDLQSK
TAFHLAAAK
122
5
6
28
38
Irs1
Lmod2
335
64
1678
486
0.18
1.06
1.03
2.75
0.41
0.05
0.48
0.51
5.09
0.30
0.68
3.58
4.05
1.50
1.30
0.24
0.94
2.12
2.43
4.05
1.03
1.17
4.09
2.12
0.79
3.15
0.18
0.39
0.82
1.54
0.62
5.28%
39.00%
3.46%
26.70%
226326
54948
105420
131160
131160
Rps27a
Hsp90aa1
Hsp90ab1
Ncl
Jup
Myh3
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
7.35%
11.00%
11.30%
10.80%
32.30%
21.50%
16.60%
7.36%
32.70%
32.70%
37.80%
38.90%
21.60%
5.16%
21.50%
55.70%
12.40%
21.50%
3.65%
3.30%
31.60%
34.10%
8.26%
13.30%
31.30%
31.30%
32.70%
6.79%
54.10%
5.34%
42.20%
48.10%
7.36%
33.30%
4.68%
37.60%
53.00%
19.70%
15.90%
14.50%
8.81%
3.17%
39.20%
131160
Pik3ca
Copa
Myh9
Cand1
Myh3
Copg
Nes
Dsp
Tmod1
Myo1c
Myo1c
Myo1d
Gars
Mprip
Hspd1
Krt77
Kab
Krt13
Cltc
Copb1
326
51
0.08
0.02
2
2
2
2
2
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
S1:Phospho(+79.97)
S3:Phospho(+79.97)
T4:Phospho(+79.97)
T5:Phospho(+79.97)
472
67
217
226
485
1388
273
198
1179
331
1278
1235
232
1484
306
656
319
79
4
49
2
47
IPI00209113
IPI00373332
IPI00914189
IPI00199662
IPI00199662
Pik3r2
Hspa5
Myh3
Krt42
Krt35
9.24
2.22
2
2
1,151.60
1,527.69
1,465.70
1,521.76
940.5944
824.4266
1,612.81
1,116.55
1,519.70
1,098.45
1,500.69
2,634.19
2,634.19
2,554.22
1,097.62
1,168.71
1,081.64
1,916.90
2,076.01
986.5094
1,106.51
1,905.90
1,560.72
2,719.32
1,122.55
1,560.73
1,836.93
1,481.81
1,532.79
1,688.89
1,900.96
M4:Oxidation(+15.99)
463
51
206
206
469
1376
258
185
1169
318
1270
1226
224
1477
299
645
307
70
2
4
16
6
38
83
17
12
116
116
78
141
25
5
29
3511
12
29
3
23
85
126
7
9
93
93
116
3
21
3
172
221
12
10
12
120
43
74
71
130
6
3
69
IPI00199662
Rps27a
Krt42
Thbs1
Rai14
Specc1l
Krt17
2
2
2,080.95
1,005.52
1,150.59
1,526.68
1,464.69
1,520.76
939.5862
823.4188
1,611.80
1,115.55
1,518.70
1,097.44
1,499.68
2,633.19
2,633.19
2,553.22
1,096.61
1,167.70
1,080.63
1,915.90
2,075.00
985.4976
1,105.51
1,904.90
1,559.72
2,718.32
1,121.54
1,559.72
1,835.93
1,480.80
1,531.79
1,687.89
1,899.95
M10:Oxidation(+15.99)
M9:Oxidation(+15.99)
M5:Oxidation(+15.99)
0.38
3.94
0.15
9.17
0.56
3.76
3.67
1.59
2.30
1.73
0.04
3.84
0.63
0.55
0.26
3.05
4.82
1.56
4
23
2
23
Insulinreceptorsubstrate1
LOC687295
Atp5b
Tpm2
Tpm2
Krt33a
Hadha
Hip1
Tuba1b
Rrbp1
Actn1
Myo1d
Myo1d
1,158.66
1,444.71
2,079.95
1,004.51
576.3029
764.3492
733.3546
761.3872
470.8009
412.7172
806.9085
558.7805
760.3593
549.73
750.8491
1,317.60
878.738
1,277.62
549.3137
584.8568
541.3229
958.9572
1,038.51
493.7566
553.7604
953.4572
780.8662
1,360.17
561.7777
780.8691
918.971
741.4075
766.9005
844.9517
950.9824
M8:Oxidation(+15.99)
M13:Oxidation(+15.99)
S1:Phospho(+79.97)
Y5:Phospho(+79.97)
2
2
2
2
3
2
3
2
2
2
2
2
2
2
2
2
2
2
2
4
11
5
24
51
8
6
49
49
53
55
10
5
29
222
12
29
3
7
40
42
6
9
39
39
49
3
3
3
76
53
6
8
9
54
22
9
6
4
5
3
39
Myosin9
similartocoronin,actinbindingprotein,2B
Eukaryotictranslationinitiationfactor3subunitC
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
Syncrip
Clip2
Myh9
Myh9
Eef1a1
Irs1
Irs1
Irs1
Irs1
1,157.64
1,443.70
1,040.98
503.2636
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
1,014.57
1,928.91
1,356.65
2,520.19
2,012.00
1,471.81
1,903.98
1,639.88
1,292.71
1,505.74
1,006.54
1,187.64
1,102.55
924.5044
858.5048
1,451.74
1,527.74
1,275.63
4
19
2
17
Myh9
Coro2b
Eif3c
Irs1
Irs1
Pik3cb
Ppp1r12a
Atp5a1
Copa
579.8303
722.859
M2:Oxidation(+15.99),M6:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M3:Oxidation(+15.99)
1,013.56
1,927.91
1,355.65
2,519.20
2,010.99
1,470.81
1,902.98
1,638.88
1,291.71
1,504.74
1,005.53
1,186.64
1,101.54
923.496
857.4972
1,450.73
1,526.74
1,274.62
2
3
10
5
22
40
8
6
39
39
44
44
8
5
27
138
12
27
3
7
30
31
6
9
28
28
39
3
2
3
69
43
6
7
8
45
22
7
4
3
5
3
34
Irs1
Nedd4
Myh10
Hadha
P4hb
Col1a1
Col1a2
M6:Oxidation(+15.99)
507.7885
964.9648
678.8306
1,260.61
671.3381
736.4127
635.3342
820.4456
646.8605
753.3776
503.775
594.3254
551.7802
462.7558
429.7564
726.3753
764.3798
638.3196
M12:Oxidation(+15.99)
M8:Oxidation(+15.99)
M8:Oxidation(+15.99)
S1:Phospho(+79.97)
T2:Phospho(+79.97)
T3:Phospho(+79.97)
T3:Phospho(+79.97)
M7:Oxidation(+15.99)
M5:Oxidation(+15.99)
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
M7:Oxidation(+15.99)
M3:Oxidation(+15.99),M7:
Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
S8:Phospho(+79.97),M12:
Oxidation(+15.99)
T7:Phospho(+79.97),M12:
Oxidation(+15.99)
M10:Oxidation(+15.99)
M20:Oxidation(+15.99)
968.4796
1,934.94
1,935.95
2
1.09
667
684
TRUE
991.4849
626.845
593.3657
771.3989
440.7304
910.1213
913.449
651.999
603.325
890.9052
621.7863
509.2886
960.4667
967.4752
1,980.95
1,251.67
1,184.72
1,540.78
879.4451
2,727.34
1,824.88
1,952.97
1,204.63
1,779.79
1,241.56
1,016.56
1,918.92
1,932.93
1,981.95
1,252.68
1,185.72
1,541.79
880.453
2,728.34
1,825.88
1,953.98
1,205.64
1,780.80
1,242.56
1,017.57
1,919.92
1,933.94
2
2
2
2
2
3
2
3
2
2
2
2
2
2
3.71
2.66
2.30
0.82
0.10
3.28
4.43
2.08
0.13
2.01
0.42
0.04
2.88
3.49
675
528
508
385
1050
44
153
153
290
70
351
308
1146
1190
692
539
518
398
1057
67
168
169
299
86
360
315
1162
1206
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
642.8593
1,283.70
1,284.71
2
4.12
34
45
TRUE
601.7501
593.7543
1,201.48
1,185.49
1,202.49
1,186.50
2
2
0.34
3.12
1505
1505
1514
1514
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
858.8693
437.7354
877.9714
776.8803
1,049.02
1,715.72
873.4552
1,753.93
1,551.74
2,096.03
1,716.73
874.4635
1,754.93
1,552.75
2,097.03
2
2
2
2
2
0.02
0.45
3.43
0.21
5.90
1505
434
845
300
300
1519
440
860
315
320
726.3371
2,175.99
2,177.00
3
0.19
300
320
TRUE
726.3367
776.9014
736.0432
654.3488
998.5239
764.0572
461.7615
580.7935
805.944
422.7611
693.8851
2,175.99
1,551.79
2,205.11
1,960.02
1,995.03
2,289.15
921.5074
1,159.57
1,609.87
843.5065
1,385.75
2,177.00
1,552.79
2,206.10
1,961.03
1,996.03
2,290.14
922.5151
1,160.58
1,610.88
844.5146
1,386.76
3
2
3
3
2
3
2
2
2
2
2
0.38
1.13
4.17
1.20
3.26
7.43
0.17
0.81
2.90
0.39
2.14
300
139
509
317
273
250
370
241
134
565
124
320
152
526
333
289
271
376
252
149
572
137
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
545.7924
458.7232
891.4146
995.8415
656.3353
885.4674
1,089.57
915.4308
1,780.81
2,984.50
1,965.98
1,768.92
1,090.57
916.4378
1,781.82
2,985.49
1,966.99
1,769.92
2
2
2
3
3
2
2.16
0.91
1.05
4.88
2.38
4.44
706
42
310
135
542
801
716
49
326
164
563
821
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
648.6764
684.8563
720.3391
404.7206
1,943.01
1,367.70
1,438.66
807.4256
1,944.01
1,368.70
1,439.67
808.4318
3
2
2
2
0.14
2.70
1.13
2.01
930
443
46
282
946
456
58
288
TRUE
TRUE
TRUE
TRUE
656.3312
635.3394
629.7968
621.8007
530.2997
766.3516
766.3535
766.3525
726.3655
1,310.65
1,902.99
1,257.58
1,241.59
1,587.88
1,530.69
1,530.69
1,530.69
1,450.72
1,311.65
1,904.00
1,258.59
1,242.59
1,588.88
1,531.69
1,531.69
1,531.69
1,451.72
2
3
2
2
3
2
2
2
2
0.03
1.75
0.51
2.78
1.33
3.21
5.68
4.41
0.65
131
854
1182
1182
6
520
520
520
520
142
870
1191
1191
20
533
533
533
533
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
629.346
639.8226
769.8657
703.3607
494.7696
813.4276
514.2938
1,004.45
611.3265
715.3872
598.8366
838.9666
1,256.68
1,277.63
1,537.72
1,404.71
987.5236
1,624.84
1,026.57
2,006.89
1,220.64
1,428.76
1,195.66
1,675.92
1,257.68
1,278.64
1,538.72
1,405.71
988.5317
1,625.84
1,027.58
2,007.89
1,221.64
1,429.77
1,196.66
1,676.92
2
2
2
2
2
2
2
2
2
2
2
2
3.04
0.79
0.50
4.98
0.27
2.95
0.63
1.72
4.03
0.88
1.05
1.84
285
110
252
252
109
236
755
41
1054
727
791
898
295
121
264
264
116
249
763
60
1064
738
801
913
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
894.4694
559.293
623.8561
641.8015
408.5759
611.8254
1,786.92
1,116.57
1,245.70
1,281.59
1,222.70
1,221.64
1,787.93
1,117.57
1,246.70
1,282.59
1,223.71
1,222.64
2
2
2
2
3
2
1.66
3.53
2.97
0.22
0.63
0.17
12
430
289
662
194
171
27
439
299
672
203
180
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
2
2
2
2
2
501.7835
535.6272
612.8151
633.8391
613.3259
1,001.55
1,603.86
1,223.61
1,265.66
1,224.64
1,002.56
1,604.87
1,224.62
1,266.67
1,225.64
2
3
2
2
2
0.52
0.48
0.17
0.80
0.93
534
124
1374
181
184
541
138
1383
190
193
TRUE
TRUE
TRUE
TRUE
TRUE
29.2
25.4
26.6
28
28.7
26.8
27.7
25.1
29.1
28.9
28.7
26.4
25
28
29.1
25.7
26.8
27.7
28.5
23.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
667.3471
595.8447
403.2015
586.3035
581.2921
586.8322
936.0018
756.9237
1,154.59
690.8554
512.9393
561.3143
722.3953
958.5015
760.8823
551.6434
584.8153
917.4871
626.8364
658.3875
1,999.02
1,189.67
804.3874
1,170.59
1,160.57
1,171.65
1,869.99
1,511.83
2,307.17
1,379.70
1,535.79
1,120.61
2,164.16
1,914.99
1,519.75
1,651.91
1,167.62
1,832.96
1,251.66
1,314.76
2,000.02
1,190.68
805.3945
1,171.60
1,161.58
1,172.65
1,870.99
1,512.84
2,308.17
1,380.70
1,536.80
1,121.62
2,165.16
1,916.00
1,520.75
1,652.91
1,168.62
1,833.96
1,252.66
1,315.76
3
2
2
2
2
2
2
2
2
2
3
2
3
2
2
3
2
2
2
2
1.30
2.49
0.96
2.53
0.98
3.26
4.39
0.43
4.19
1.35
0.10
0.03
4.36
1.57
3.08
1.35
1.08
1.62
3.05
6.52
1025
563
1175
1014
1252
805
28
1770
29
703
703
686
614
2114
206
173
640
319
87
340
1041
572
1181
1023
1261
815
44
1782
49
714
715
694
633
2133
218
186
649
334
96
351
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
FALSE
TRUE
TRUE
28.2
27.2
27.3
28.8
19.6
28.2
2
2
2
2
2
2
541.2803
683.3701
683.3693
834.4327
645.7077
908.9807
1,080.55
1,364.72
1,364.72
2,500.27
1,934.10
1,815.95
1,081.55
1,365.73
1,365.73
2,501.27
1,935.10
1,816.95
2
2
2
3
3
2
0.30
1.46
0.30
6.51
2.42
0.83
55
88
83
491
427
69
63
100
95
512
444
84
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
M6:Oxidation(+15.99)
M9:Oxidation(+15.99)
S3:Phospho(+79.97)
S7:Phospho(+79.97)
T6:Phospho(+79.97)
M4:Oxidation(+15.99)
M9:Oxidation(+15.99)
M10:Oxidation(+15.99)
M12:Oxidation(+15.99)
M15:Oxidation(+15.99)
M9:Oxidation(+15.99)
M11:Oxidation(+15.99)
M11:Oxidation(+15.99)
M12:Oxidation(+15.99)
714.3474
M2:Oxidation(+15.99),M15:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M15:
Oxidation(+15.99)
M2:Oxidation(+15.99)
M5:Oxidation(+15.99)
M8:Oxidation(+15.99)
M10:Oxidation(+15.99)
713.3396
714.3464
1
1.42
98
104
1,880.93
1,319.68
1,881.93
1,320.68
2
2
4.89
4.37
306
542
321
553
TRUE
TRUE
1,923.93
1,213.64
1,264.63
1,392.73
1,586.79
1,243.62
1,261.60
1,221.59
1,703.88
784.4811
972.4963
1,240.62
1,822.88
1,924.94
1,214.65
1,265.64
1,393.73
1,587.80
1,244.62
1,262.60
1,222.60
1,704.89
785.4886
973.503
1,241.63
1,823.88
2
2
2
2
2
2
2
2
2
1
2
2
2
0.27
2.54
1.48
0.11
1.56
0.07
1.96
0.53
1.96
0.44
1.17
0.03
2.77
344
560
277
277
101
136
114
105
681
691
866
875
547
359
569
287
288
113
145
124
115
695
697
874
886
564
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
131160
61700
29
7
39
7
105
13
31.90%
14.20%
TPSQSSVVSIEEYTEMMPAAYPPGGGSGGR
TPTGNFSR
K
K
L
E
40.8
28.6
31.7
25.9
2
2
M16:Oxidation(+15.99),M17:
Oxidation(+15.99)
1,025.46
440.2206
3,073.37
878.4256
3,074.37
879.4325
3
2
81251
26
30
83
47.20%
TQAEEMLSGK
R
R
37.6
27.8
2
M6:Oxidation(+15.99)
555.262
1,108.51
1,109.52
2
1.02
624
633
TRUE
81251
226326
109514
257845
26
90
13
35
30
118
13
51
83
358
13
95
47.20%
45.50%
17.30%
18.00%
TQAEEMLSGKR
TQLEELEDELQATEDAK
TQMLDQEELLASTR
TQNVHVEIEQR
R
K
K
K
D
L
R
W
37.8
138
85.1
62.3
28.7
30
29.4
28.6
2
2
2
2
M6:Oxidation(+15.99)
633.3115
981.4683
825.9072
676.85
1,264.61
1,960.92
1,649.80
1,351.68
1,265.62
1,961.92
1,650.80
1,352.69
2
2
2
2
0.74
4.75
3.42
0.03
624
1540
451
597
634
1556
464
607
TRUE
TRUE
TRUE
TRUE
83516
62207
50196
34198
119797
5
11
2
4
47
6
14
3
4
62
6
39
19
10
175
7.32%
13.30%
25.90%
20.80%
46.60%
TQSSSNPAELR
TREEINELNR
TRLEQEIATYR
TSFFQALGITTK
TSFLLNLR
R
R
K
K
R
Q
I
R
I
R
52
47.2
68.3
95.7
71.9
27.7
28.5
28.2
27.3
23.2
2
2
2
2
2
595.2949
637.3236
690.3687
657.3624
482.2857
1,188.57
1,272.63
1,378.72
1,312.71
962.5558
1,189.58
1,273.65
1,379.73
1,313.71
963.5628
2
2
2
2
2
0.65
8.41
0.82
4.77
0.86
152
316
385
135
795
162
325
395
146
802
TRUE
TRUE
FALSE
TRUE
TRUE
80257
59737
191585
156634
82231
2
4
3
44
6
2
4
3
53
7
2
5
3
78
7
4.29%
7.78%
3.70%
37.80%
14.00%
TSHQALESELQQLR
TSIAIDTIINQK
TSIDAYDNFDNISLAQR
TSPGSPSPR
TSSAEMPTIPLGSAVEAIR
K
K
R
K
K
A
R
L
S
V
42.9
56.7
76.6
37.3
31.2
28.4
25.8
30.3
25.3
28.8
2
2
2
2
2
547.2854
658.877
971.9611
443.2269
973.5015
1,638.83
1,315.74
1,941.91
884.4382
1,944.99
1,639.84
1,316.74
1,942.91
885.4431
1,945.99
3
2
2
2
2
0.17
2.62
0.11
3.35
2.40
318
219
1482
1294
565
331
230
1498
1302
583
TRUE
TRUE
TRUE
TRUE
TRUE
M3:Oxidation(+15.99)
M6:Oxidation(+15.99)
534
59
563
66
IPI00371976
IPI00765011,IPI00360356,IPI00189819
IPI00200792,IPI00421785
IPI00421795
IPI00213463
IPI00370073
IPI00382153,IPI00393340,IPI00207038
IPI00370090
IPI00471584
IPI00210566
TRUE
941.4736
660.8485
962.9722
607.8303
633.3237
697.3704
794.4041
622.8156
631.806
611.8021
852.9484
785.489
487.256
621.3195
912.4473
0.93
1.15
IPI00393340
TRUE
TRUE
IPI00391300,IPI00558912
IPI00421795,IPI00370073,IPI00421855
Lima1
Kab
Capza2
Krt5
Krt5
Sec31a
Gnai2
Acta1
Actb
Myh3
Myh10
Pik3r2
Hspa9
Hspa8
Smtn
Ddx5
Myh3
Myh9
LOC687295
Hadha
Krt33a
Krt10
Hadha
Kpnb1
Hist4h4
Rai14
Hspa8
Clip2
Vim
Vim
similartoEpithelialproteinlostinneoplasm
IPI00373011
83779
174kDaprotein
IPI00776774
173996
Factincappingproteinsubunitalpha2
IPI00370681
32949
Keratin,typeIIcytoskeletal5
IPI00382153
61809
Keratin,typeIIcytoskeletal5
IPI00382153
61809
Isoform1ofProteintransportproteinSec31A
IPI00210147,IPI00515833
135256
GuaninenucleotidebindingproteinG(i),alpha2subunit IPI00231925
40482
Actin,alphaskeletalmuscle
IPI00189813
42034
Actin,cytoplasmic1
IPI00189819,IPI00765011,IPI00896224 41720
Myosin3
IPI00201578
223846
234kDaprotein
IPI00391300
233603
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
81251
Stress70protein,mitochondrial
IPI00363265
73840
Heatshockcognate71kDaprotein
IPI00208205
70855
smoothelin
IPI00361871,IPI00561311
99862
Ddx5
IPI00464718
69223
Myosin3
IPI00201578
223846
Myosin9
IPI00209113
226326
similartotranslocaseofinnermitochondrialmembrane50
homologisoform2
IPI00766169
39838
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
TypeIhairkeratinKA27
IPI00551773
45954
Keratin,typeIcytoskeletal10
IPI00421806,IPI00551673
56489
Trifunctionalenzymesubunitalpha,mitochondrial
IPI00212622
82649
Importinsubunitbeta1
IPI00204261
97167
IPI00231340,IPI00364897,IPI00368659,I
PI00559188,IPI00561052,IPI00561706,I
HistoneH4
PI00764726,IPI00778180
11464
Isoform2ofAnkycorbin
IPI00372146
105981
Heatshockcognate71kDaprotein
IPI00208205
70855
111kDaprotein
IPI00476704
111364
Vimentin
IPI00230941
53716
Vimentin
IPI00230941
53716
5
4
3
18
22
4
4
2
6
69
57
6
4
3
24
28
4
4
3
12
76
66
11
4
6
456
602
4
4
10
254
172
435
7.95%
2.72%
17.80%
28.30%
30.00%
3.84%
16.10%
59.40%
48.80%
42.20%
39.20%
TSSLPESSPSK
TSSMEISSILQELK
TSVETALR
TTAENEFVMLK
TTAENEFVMLKK
TTFEDLIQR
TTGIVETHFTFK
TTGIVLDSGDGVTHNVPIYEGYALPHAIMR
TTGIVMDSGDGVTHTVPIYEGYALPHAILR
TTHPHFVR
TTLQVDTLNTELAAER
R
K
R
R
R
K
K
R
R
R
K
T
R
A
K
D
C
D
L
L
C
S
53.7
55.7
58
70.4
39.8
35.8
46.9
77.7
59.9
32.4
107
28.4
29.4
27.8
28.7
28.4
27.9
28.2
29.2
29
27.6
28
2
2
2
2
2
2
2
2
2
2
2
24
8
16
9
3
60
119
28
8
19
9
3
66
194
88
17
59
12
6
306
3095
47.20%
16.60%
33.30%
11.60%
5.04%
39.10%
51.60%
TTLYDAVK
TTPSVVAFTPDGER
TTPSYVAFTDTER
TTTVESSFVR
TTYLVLDEADR
TVETMQGALDAEVR
TVGQLYK
R
R
R
R
R
R
R
G
L
L
R
M
S
E
35.9
75.1
100
55.9
66.3
104
47
26.2
28.8
29.8
28.1
28.8
29.5
23.3
2
2
2
2
2
2
2
3
7
2
14
7
8
3
8
2
22
8
8
3
10
4
365
10
9
12.50%
15.30%
9.41%
24.50%
15.30%
13.20%
TVLEHYALEDDPLEAFK
TVLGVPEVLLGILPGAGGTQR
TVNALEIELQAQHNLR
TVQGLEIELQSQLALK
TVQQLAILGAGLMGAGIAQVSVDK
TVSPDRLELEAAQK
R
K
R
R
K
K
Q
L
N
Q
G
F
36.3
64.7
60.5
95.4
28.8
35.7
30
17.5
26.8
23.5
23.5
27.1
2
2
2
2
2
2
2
31
19
30
29
28
2
39
23
33
39
40
2
61
49
42
105
261
19.20%
36.40%
39.00%
33.70%
67.20%
62.20%
TVTAMDVVYALK
TVTLQEHLASK
TVTNAVVTVPAYFNDSQR
TYQTEVDKLR
TYSLGSALR
TYSLGSALRPSTSR
K
K
K
K
R
R
R
E
Q
A
P
S
44.6
71.5
67.8
35.6
36.3
47.6
27
26.4
28.7
28.3
25.4
27.7
2
2
2
2
2
2
560.2813
791.4064
438.7435
649.8192
476.2474
561.7954
690.8637
1,071.54
1,067.21
497.7651
887.9656
1,118.55
1,580.80
875.4714
1,297.62
1,425.72
1,121.58
1,379.71
3,211.61
3,198.62
993.5146
1,773.92
1,119.55
1,581.80
876.4791
1,298.63
1,426.73
1,122.58
1,380.72
3,212.61
3,199.61
994.5223
1,774.92
2
2
2
2
3
2
2
3
3
2
2
1.23
0.26
0.18
0.12
0.97
2.97
2.24
3.09
5.77
0.16
2.57
365
1459
122
262
262
1150
182
150
148
665
1799
375
1472
129
272
273
1158
193
179
177
672
1814
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
455.7483
738.8704
744.3555
563.7904
648.3275
768.374
404.7322
909.481
1,475.73
1,486.70
1,125.57
1,294.64
1,534.73
807.4487
910.4887
1,476.73
1,487.70
1,126.57
1,295.65
1,535.74
808.457
2
2
2
2
2
2
2
0.11
0.47
0.93
1.38
1.01
1.69
0.63
168
86
37
686
242
1594
645
175
99
49
695
252
1607
651
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
664.0012
683.0726
617.0033
885.5065
786.1061
778.9215
1,988.98
2,046.19
1,847.99
1,769.00
2,355.29
1,555.83
1,989.98
2,047.19
1,848.99
1,770.00
2,356.29
1,556.83
3
3
3
2
3
2
3.45
4.97
0.48
2.09
4.83
4.26
296
167
278
370
360
10
312
187
293
385
383
23
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
663.856
613.8411
661.3388
418.2228
484.2643
499.2686
1,325.70
1,225.67
1,980.99
1,251.65
966.5129
1,494.78
1,326.70
1,226.67
1,982.00
1,252.65
967.5213
1,495.79
2
2
3
3
2
3
4.72
0.17
1.37
0.85
0.66
2.07
82
720
138
539
37
37
93
730
155
548
45
50
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
462.7304
518.7875
566.332
M11:Oxidation(+15.99),M14:
Oxidation(+15.99),M25:
Oxidation(+15.99)
986.4694
M4:Oxidation(+15.99)
651.3206
489.2879
923.4452
1,035.56
1,130.65
924.4536
1,036.57
1,131.65
2
2
2
0.55
0.67
3.27
804
1406
872
811
1414
882
TRUE
TRUE
TRUE
2,956.38
1,300.63
976.5602
2,957.38
1,301.63
977.5672
3
2
2
4.10
4.81
0.85
260
198
330
284
209
338
TRUE
TRUE
TRUE
678.368
624.3259
720.4019
809.4066
1,354.72
1,246.64
1,438.79
1,616.80
1,355.73
1,247.64
1,439.79
1,617.81
2
2
2
2
0.15
1.79
4.27
0.35
36
212
282
265
49
222
294
279
TRUE
TRUE
TRUE
TRUE
2,073.07
1,097.58
1,953.06
1,955.05
2,296.23
1,953.07
2,294.24
686.4328
981.561
2,074.08
1,098.58
1,954.07
1,956.04
2,297.23
1,954.07
2,295.25
687.4406
982.5686
2
2
3
2
4
2
4
1
2
0.19
3.81
0.33
4.39
3.36
4.39
1.13
0.03
0.29
739
1398
97
98
98
96
96
35
327
758
1406
114
115
118
113
116
41
335
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
M4:Oxidation(+15.99)
M9:Oxidation(+15.99)
M9:Oxidation(+15.99)
M29:Oxidation(+15.99)
M6:Oxidation(+15.99)
M5:Oxidation(+15.99)
M13:Oxidation(+15.99)
M5:Oxidation(+15.99)
M4:Oxidation(+15.99),M6:
Oxidation(+15.99)
Myo1d
Myh9
Emilin1
MyosinId
Myosin9
elastinmicrofibrilinterfacer1
IPI00207989
IPI00209113
IPI00199867
116081
226326
107542
52
123
11
69
194
11
255
2027
11
53.00%
52.30%
15.40%
VAAMEMLK
VAAYDKLEK
VAFSAALSLPR
K
K
R
G
T
S
49.1
55.8
85.9
28.2
26.4
24.6
2
2
2
Tpm1
Nes
Ncl
IPI00210945
IPI00194103
IPI00231827,IPI00882501
32831
208776
77259
18
16
6
28
17
6
79
27
7
41.90%
10.50%
8.26%
VAHAKEENLSMHQMLDQTLLELNNM
VAHMESSLGQAR
VAISELFAK
K
R
K
E
N
31.8
37.6
46
31.4
28.4
22.7
2
2
2
Pik3r2
Npepps
Atp5b
Atp5b
tropomyosin1,alphaisoformc
Isoform1ofNestin
Nucleolin
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
aminopeptidasepuromycinsensitive
ATPsynthasesubunitbeta,mitochondrial
ATPsynthasesubunitbeta,mitochondrial
IPI00554334
IPI00372700
IPI00551812
IPI00551812
81251
103329
56336
56336
26
6
2
5
30
6
3
6
71
6
7
6
47.90%
8.26%
5.48%
14.60%
VALQALGVADGGER
VALSNMNVIDR
VALTGLTVAEYFR
VALVYGQMNEPPGAR
R
R
R
K
C
K
D
A
99.4
43.4
97.5
75.3
27
27.9
25
29.6
2
2
2
2
Vcl
Cltc
Actbl2
Acta1
Acta1
Actb
Actb
Rai14
Rai14
Vinculin
Clathrinheavychain1
actin,betalike2
Actin,alphaskeletalmuscle
Actin,alphaskeletalmuscle
Actin,cytoplasmic1
Actin,cytoplasmic1
Isoform2ofAnkycorbin
Isoform2ofAnkycorbin
IPI00365286
IPI00193983
IPI00360356
IPI00189813
IPI00189813
IPI00189819,IPI00765011,IPI00896224
IPI00189819,IPI00765011,IPI00896224
IPI00372146
IPI00372146
116599
191585
41946
42034
42034
41720
41720
105981
105981
17
18
2
2
2
6
7
34
31
18
19
2
3
4
12
13
39
39
25
19
2
15
23
122
174
69
61
20.40%
14.40%
22.60%
57.80%
58.60%
53.90%
54.70%
39.20%
36.40%
VAMANIQPQMLVAGATSIAR
VANVELYYK
VAPDEHPILLTEAPLNPK
VAPEEHPTLLTEAPLNPK
VAPEEHPTLLTEAPLNPKANR
VAPEEHPVLLTEAPLNPK
VAPEEHPVLLTEAPLNPKANR
VASLLGK
VASLTLHNK
K
K
R
R
R
R
R
K
K
R
A
I
A
E
A
E
K
E
71.6
57.2
26.9
64.8
21.6
73.8
20.9
29.4
55.5
28.1
26.3
26
26.7
25.3
25.4
24.1
27.2
22.6
2
2
2
2
2
2
2
2
2
Krt5
P4hb
Myh10
Tmpo
Keratin,typeIIcytoskeletal5
Proteindisulfideisomerase
234kDaprotein
75kDaprotein
18
3
58
3
24
3
67
3
456
3
363
3
28.30%
12.40%
40.00%
6.79%
VDALMDEINFMK
VDATEESDLAQQYGVR
VDDDLGTIEGLEEAK
VDDEILGFISEATPR
K
K
K
K
M
G
K
A
80.8
69.8
85.3
83.4
29.1
29.4
29.5
28.9
2
2
2
2
1,456.66
1,779.83
1,602.77
1,660.84
1,457.67
1,780.84
1,603.77
1,661.84
2
2
2
2
0.61
3.38
3.30
4.06
289
84
1417
534
300
99
1431
548
TRUE
TRUE
TRUE
TRUE
Tnnt2
Isoform2ofTroponinT,cardiacmuscle
15
27
87
38.80%
VDFDDIHR
R
K
59.7
27.3
2
508.7439
1,015.47
1,016.48
2
0.26
87
94
TRUE
Tnnt2
Isoform2ofTroponinT,cardiacmuscle
IPI00382153
61809
IPI00198887
56935
IPI00391300
233603
IPI00569391
74885
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
M8:Oxidation(+15.99)
M3:Oxidation(+15.99),M10:
Oxidation(+15.99)
1,037.54
549.7977
652.0272
978.5305
575.0642
977.5408
574.5681
687.4406
491.7883
M5:Oxidation(+15.99),M11:
Oxidation(+15.99)
729.3372
890.9246
802.3919
831.4268
14
24
111
37.00%
VDFDDIHRK
R
R
45.3
28.4
2
572.7919
1,143.57
1,144.58
2
0.67
87
95
TRUE
Tnnt3
Isoform1ofTroponinT,fastskeletalmuscle
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
12
16
46
34.40%
VDFDDIQK
K
K
42.8
26.5
2
490.2405
978.4654
979.474
2
0.71
55
62
TRUE
Tnnt3
Cltc
9Sep
Krt75
Clip2
Atp1a1
Krt2
IPI00554262,IPI00560341,IPI00829459,I
Isoform1ofTroponinT,fastskeletalmuscle
PI00829466,IPI00829504,IPI00829511 30734
Clathrinheavychain1
IPI00193983
191585
septin9isoform1
IPI00215235,IPI00782707
64850
58kDaprotein
IPI00777617
57763
111kDaprotein
IPI00476704
111364
Sodium/potassiumtransportingATPasesubunitalpha1 IPI00326305
113040
Keratin,typeIIcytoskeletal2epidermal
IPI00551558,IPI00559533
69273
12
27
3
2
28
9
5
16
29
3
2
31
9
7
46
29
3
3
43
11
172
34.40%
21.50%
6.08%
10.10%
34.30%
12.10%
9.33%
VDFDDIQKK
VDKLDASESLR
VDLAGAK
VDLQAK
VDLSNQLEEERR
VDNSSLTGESEPQTR
VDPEIQNVK
K
K
R
K
K
K
K
R
K
A
A
K
S
S
31.9
45.1
29
29.5
41.9
45.2
54.9
28.1
27.8
26.8
26.8
29.3
29.5
26.2
2
2
2
2
2
2
2
554.2886
616.83
673.3889
673.3892
496.5875
810.3825
521.2827
1,106.56
1,231.64
672.3811
672.3813
1,486.74
1,618.75
1,040.55
1,107.57
1,232.65
673.3886
673.3886
1,487.75
1,619.75
1,041.56
2
2
1
1
3
2
2
0.47
2.70
0.42
0.78
0.85
3.57
0.55
55
1610
86
254
430
213
186
63
1620
92
259
441
227
194
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
Pbxip1
Atp2a2
Srp72
Myh9
Hspa9
Myh3
Pygb
Myh9
Myh9
Myh10
Myh10
Hspa8
Kb15
Vim
Actn4
Actn1
Mprip
Vim
Vim
Eef1a1
Vim
Eef2
Kab
Myo1e
Hist4h4
Copg
Copb2
Centg2
Eef2
Col1a2
Cltc
Hnrpm
Ap2a2
Tuba1b
Flii
Myh3
Ddx3x
Col1a1
Psmd2
Lima1
Pygb
Myo1d
LOC682005;G
apdh;LOC685
186
LOC682005;G
apdh;LOC685
186
Krt15
Hsp90ab1
Hspa9
Myh3
Myh9
Myh9
Myh9
Smtn
Myo1d
Mprip
Myo1d
Myh9
Myh10
Myh9
Actn4
M6:Oxidation(+15.99)
PreBcellleukemiatranscriptionfactorinteractingprotein1 IPI00201858
80257
IsoformSERCA2BofSarcoplasmic/endoplasmicreticulum
calciumATPase2
IPI00190020,IPI00231369
115376
similartoSignalrecognitionparticle72kDaprotein
IPI00763992,IPI00766213,IPI00766719 73844
Myosin9
IPI00209113
226326
Stress70protein,mitochondrial
IPI00363265
73840
Myosin3
IPI00201578
223846
Phosphorylase
IPI00357945
96759
Myosin9
IPI00209113
226326
Myosin9
IPI00209113
226326
234kDaprotein
IPI00391300
233603
234kDaprotein
IPI00391300
233603
Heatshockcognate71kDaprotein
IPI00208205
70855
TypeIIkeratinKb15
IPI00207038
58080
Vimentin
IPI00230941
53716
Alphaactinin4
IPI00213463
104900
Alphaactinin1
IPI00209082,IPI00454431
102946
258kDaprotein
IPI00392930
257845
Vimentin
IPI00230941
53716
Vimentin
IPI00230941
53716
Elongationfactor1alpha1
IPI00195372,IPI00551729
50096
Vimentin
IPI00230941
53716
Elongationfactor2
IPI00203214
95268
174kDaprotein
IPI00776774
173996
MyosinIe
IPI00207988,IPI00388110
126813
IPI00231340,IPI00364897,IPI00368659,I
PI00559188,IPI00561052,IPI00561706,I
PI00764726,IPI00778180
11464
HistoneH4
Coatomersubunitgamma
IPI00780394
98515
Coatomersubunitbeta'
IPI00231953
102535
centaurin,gamma2
IPI00389524
96839
Elongationfactor2
IPI00203214
95268
Collagenalpha2(I)chain
IPI00188921
129547
Clathrinheavychain1
IPI00193983
191585
heterogeneousnuclearribonucleoproteinMisoformaIPI00876603
77613
Adaptorrelatedproteincomplex2,alpha2subunit
IPI00471901
104159
Tubulinalpha1Bchain
IPI00339167
50134
FlightlessIhomolog
IPI00211698
144843
Myosin3
IPI00201578
223846
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
73130
collagen,type1,alpha1
IPI00844828
137936
26SproteasomenonATPaseregulatorysubunit2
IPI00370456
100172
similartoEpithelialproteinlostinneoplasm
IPI00373011
83779
Phosphorylase
IPI00357945
96759
MyosinId
IPI00207989
116081
2
2
2
4.29%
VDPESEEAPQALQDSSK
R
A
65.9
30.1
2
5
3
113
13
86
6
132
132
70
38
16
2
36
24
22
35
28
28
8
36
11
8
2
5
3
179
13
104
6
196
196
82
44
19
3
48
28
26
51
40
40
10
48
12
8
2
7
3
1862
23
217
6
883
883
145
150
59
114
124
44
34
95
261
261
25
124
16
12
2
6.70%
7.39%
50.90%
28.00%
50.30%
8.51%
55.20%
55.20%
45.50%
29.70%
33.30%
14.00%
74.00%
34.60%
41.70%
18.00%
62.20%
62.20%
21.60%
74.00%
15.50%
5.19%
3.52%
VDQSILTGESVSVIK
VDVEALENSPGATYIR
VEAQLQELQVK
VEAVNMAEGIIHDTETK
VEDEQTLSLQLQK
VEDVEALDQK
VEEEAAQK
VEEEEER
VEEEEERNQILQNEK
VEGELEEMER
VEIIANDQGNR
VELEAK
VELQELNDR
VEQIAAIAQELNELDYYDSHNVNTR
VEQIAAIAQELNELDYYDSPSVNAR
VESGYFSLEK
VESLQEEIAFLK
VESLQEEIAFLKK
VETGVLKPGMVVTFAPVNVTTEVK
VEVERDNLAEDIMR
VFDAIMNFR
VFDESLNFR
VFDFLVDSINK
R
K
K
R
K
R
R
R
R
K
K
K
K
R
R
R
K
K
R
R
K
R
R
H
K
F
M
K
G
N
C
K
K
T
V
F
C
C
A
K
L
S
L
K
K
A
69.1
46.8
70.2
32
94.9
55
44.9
35
35.7
61.5
76.1
33.4
57.2
70.7
62.5
64.7
71
47.2
45.1
51.7
69.4
69.6
60.9
24
29.3
26.1
30.3
28
28.4
25.8
26.8
30.2
27.7
27.6
26
28
30.9
30
28.6
26.9
24.3
23.7
29.9
27.5
27.9
26.8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
9
3
5
8
13
27
3
2
11
6
86
7
17
3
5
6
42
2
9
3
6
8
13
29
3
2
13
6
104
7
17
3
6
6
50
3
10
3
11
9
13
29
6
2
47
8
217
9
17
3
11
6
166
17.30%
12.90%
3.87%
5.91%
12.10%
12.60%
21.50%
5.49%
3.19%
34.60%
5.75%
50.30%
14.00%
20.90%
4.63%
7.95%
8.51%
46.10%
VFLENVIR
VFNETPINPR
VFNYNTLER
VFQDVAQK
VFSGVVSTGLK
VGAPGPAGAR
VGEQAQVVIIDMNDPSNPIR
VGEVTYVELLMDAEGK
VGGYILGEFGNLIAGDPR
VGINYQPPTVVPGGDLAK
VGLGLGYLELPQINYK
VGNEYVTK
VGNLGLATSFFNER
VGPPGPSGNAGPPGPPGPVGK
VGQAVDVVGQAGKPK
VGVLAASMEAK
VIFLENYR
VIGFKPEEIQTVYK
K
R
R
R
R
R
K
K
K
K
K
K
R
R
R
K
R
K
D
K
V
I
V
G
R
S
S
V
L
G
N
E
T
A
V
I
35.7
40.9
55.5
58.3
70.3
37.3
36.1
82.2
58.8
61.7
69.3
44.8
62.6
62.5
36
47.4
43.3
73.9
24.8
28.2
28.4
26.5
24.7
25
29.6
29.6
28.1
26.7
23.4
26.2
28.3
28.1
23.9
27.8
26.8
24.8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Glyceraldehyde3phosphatedehydrogenase
IPI00555252,IPI00567177
7
9
33
26.10%
VIHDNFGIVEGLMTTVHAITATQK
K
T
75.1
27.3
2
M13:Oxidation(+15.99)
Glyceraldehyde3phosphatedehydrogenase
Keratin,typeIcytoskeletal15
HeatshockproteinHSP90beta
Stress70protein,mitochondrial
Myosin3
Myosin9
Myosin9
Myosin9
smoothelin
MyosinId
258kDaprotein
MyosinId
Myosin9
234kDaprotein
Myosin9
Alphaactinin4
9
4
25
6
77
113
111
138
10
28
35
52
111
57
119
22
12
5
26
6
85
179
172
222
10
31
51
69
172
66
194
23
51
8
38
9
149
1862
2414
3511
15
48
95
255
2414
435
3095
34
34.80%
18.10%
37.00%
12.20%
47.90%
50.90%
50.00%
55.70%
13.90%
30.70%
18.00%
53.00%
50.00%
39.20%
51.60%
33.50%
VIISAPSADAPMFVMGVNHEK
VILEIDNAR
VILHLKEDQTEYLEER
VINEPTAAALAYGLDK
VIQYFATIAATGDLAK
VIQYLAHVASSHK
VISGVLQLGNIVFK
VISGVLQLGNIVFKK
VISKPLLGSTEPSDTVDSTR
VIVQQPGER
VKESEIQYLK
VKNMLLK
VKPLLNSIR
VKPLLQVTR
VKVNKDDIQK
VLAGDKNFITAEELR
R
R
K
R
R
K
R
R
R
R
R
R
K
K
K
K
Y
L
R
S
K
S
K
E
G
S
Q
S
H
Q
M
R
50.9
42.4
35.2
94.6
100
76.6
86.1
67.5
65
49.2
51.9
33.7
37.8
45.6
51.9
44.9
29.4
25.4
27.7
27.6
25.6
25.4
18.6
10.4
27.5
23.6
26.6
24
15.2
15.7
25.9
27.1
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
M12:Oxidation(+15.99),M15:
Oxidation(+15.99)
1,123.06
521.7983
672.3552
823.4468
841.4628
726.9025
743.9547
808.0067
701.3735
513.2913
618.8469
M4:Oxidation(+15.99)
431.2655
520.3355
527.3433
593.8441
559.3062
17
6
8
3
28
22
49
2
13
26
7
8
3
34
26
53
2
22
111
19
9
3
49
34
157
4
362
43.90%
29.00%
13.20%
8.47%
39.60%
41.70%
33.40%
15.00%
21.50%
VLAIDHLNEDQLR
VLALSVETDYTFPLAEK
VLANPGNSQVAR
VLAQNSGFDLQETLVK
VLAVNQENEHLMEDYER
VLAVNQENEQLMEDYEK
VLAYDKLEK
VLDELTLAR
VLDELTLSK
K
R
R
K
K
K
K
R
R
E
V
V
V
L
L
T
A
A
88.3
68.8
50.2
71.2
37.6
101
44.6
75.2
64.1
28.1
27.2
25.4
27.2
30.7
30.7
25
27.2
25.7
2
2
2
2
2
2
2
2
2
3
17
3
6
6
29
29
69
29
52
2
2
30
14
30
2
3
6
15
18
4
19
9
3
19
3
6
8
34
34
76
35
69
2
2
35
14
33
2
3
6
15
23
4
20
9
7
42
3
6
18
49
49
172
51
255
2
2
73
15
42
2
3
12
21
100
4
52
10
24.50%
29.70%
5.15%
8.26%
14.90%
32.40%
32.40%
42.20%
36.10%
53.00%
2.67%
11.80%
32.60%
20.80%
33.70%
3.61%
6.56%
13.40%
13.60%
37.20%
4.55%
33.50%
9.01%
VLDFEHFLPMLQTVAK
VLEDSDLK
VLETTVEIFNK
VLGATLSPELIQK
VLIFQEESEIPASVFVK
VLLLEANR
VLLLEANRHSPGPER
VLNASAIPEGQFIDSK
VLNELTQLK
VLNIYGR
VLPGILNDTLR
VLQAHISDTSVIVK
VLQALGSEPIQYAVPVVK
VLQDLVMDILR
VLQLEEELSLR
VLQVSIGPGLPK
VLSGDLSQLPAGVR
VLSIGDGIAR
VLTIDPTEFK
VLVDPATYGQFYGGDSYIILYNYR
VMAAENIPENPLK
VMEHFIK
VMEYINR
K
K
K
R
K
R
R
R
K
K
R
R
R
R
R
K
R
R
R
K
K
R
R
N
K
L
V
E
H
D
K
Q
D
F
M
Y
V
R
N
D
V
F
H
Y
L
L
31.4
30.9
66.1
51.5
87.3
46.9
31.8
71.5
76.5
54.1
29.3
24.2
90.3
47.4
72.2
43.9
56.8
67.5
39.5
66.5
61.3
40
43.1
28.5
27.4
26
20.8
25.5
23.3
29.6
27.8
26.5
25.2
21.3
23.4
20.9
27.4
26
15.8
24.4
25.8
26.8
29.6
27.8
28.2
28.9
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
17
43
6
10
122
30
31
43
18
50
7
10
194
40
42
59
25
62
9
17
2067
85
126
215
20.40%
48.90%
12.80%
14.60%
51.90%
31.60%
34.10%
45.00%
VMLVNSMNTVK
VMVTHGVDVTAQDSSGHSALHIAAK
VNEHITSVNVESNFITGK
VNFTVDQIR
VNKDDIQK
VNLSPNHNQSAK
VNLSPNHNQSAK
VNNININQGSITFAGGPGR
R
K
K
M
K
R
R
R
E
N
G
A
M
V
V
D
39.2
51.2
59.2
67.9
51.5
72.6
65.2
113
29
29.1
29
28.1
26.6
29.1
28.3
28.6
2
2
2
2
2
2
2
2
35810
Tnnt2
Arbp
Kpnb1
Cct6a
Actn4
Actn1
Myh10
Krt42
Krt10
Isoform2ofTroponinT,cardiacmuscle
60SacidicribosomalproteinP0
Importinsubunitbeta1
Chaperoninsubunit6a
Alphaactinin4
Alphaactinin1
234kDaprotein
Keratin,typeIcytoskeletal42
Keratin,typeIcytoskeletal10
Myl6l
Hspa5
Vps35
Npepps
Sdpr
Clip2
Clip2
Myh3
Rai14
Myo1d
Kbtbd5
Krt85
Myo1c
Copb1
Clip2
Myo1e
Pck2
Atp5a1
Copa
Gsn
Stat1
Hspa5
Cltc
Myosinlightpolypeptide6
78kDaglucoseregulatedprotein
maternalembryonicmessage3
aminopeptidasepuromycinsensitive
Serumdeprivationresponseprotein
111kDaprotein
111kDaprotein
Myosin3
Isoform2ofAnkycorbin
MyosinId
kelchrepeatandBTB(POZ)domaincontaining5
TypeIIkeratinKb25
MyosinIc
Coatomersubunitbeta
111kDaprotein
MyosinIe
phosphoenolpyruvatecarboxykinase2
ATPsynthasesubunitalpha,mitochondrial
Copaprotein
Isoform2ofGelsolin
Ab2131
78kDaglucoseregulatedprotein
Clathrinheavychain1
IPI00555252,IPI00567177
35810
IPI00370090
48854
IPI00471584
83266
IPI00363265
73840
IPI00201578
223846
IPI00209113
226326
IPI00209113
226326
IPI00209113
226326
IPI00361871,IPI00561311
99862
IPI00207989
116081
IPI00392930
257845
IPI00207989
116081
IPI00209113
226326
IPI00391300
233603
IPI00209113
226326
IPI00213463
104900
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00200147
34198
IPI00204261
97167
IPI00188111,IPI00780515
58000
IPI00213463
104900
IPI00209082,IPI00454431
102946
IPI00391300
233603
IPI00421791
50196
IPI00421806,IPI00551673
56489
IPI00365944,IPI00392935,IPI00817070,I
PI00896236
16957
IPI00206624
72331
IPI00869568
91712
IPI00372700
103329
IPI00362416
46368
IPI00476704
111364
IPI00476704
111364
IPI00201578
223846
IPI00372146
105981
IPI00207989
116081
IPI00371293
67154
IPI00200792,IPI00421785
55803
IPI00393867
119797
IPI00211812
106996
IPI00476704
111364
IPI00207988,IPI00388110
126813
IPI00869844
70725
IPI00396910
59737
IPI00372458
138346
IPI00923716
80911
IPI00213245,IPI00382229,IPI00655247 134593
IPI00206624
72331
IPI00193983
191585
Vcl
Rai14
Lmod2
Eef2
Myh9
Irs1
Irs1
Myo1c
Vinculin
Isoform2ofAnkycorbin
Leiomodin2
Elongationfactor2
Myosin9
Insulinreceptorsubstrate1
Insulinreceptorsubstrate1
MyosinIc
IPI00365286
IPI00372146
IPI00372026
IPI00203214
IPI00209113
IPI00199662
IPI00199662
IPI00393867
116599
105981
61700
95268
226326
131160
131160
119797
M6:Oxidation(+15.99)
M8:Oxidation(+15.99)
M10:Oxidation(+15.99)
M13:Oxidation(+15.99)
M6:Oxidation(+15.99)
M12:Oxidation(+15.99)
M11:Oxidation(+15.99)
M8:Oxidation(+15.99)
M12:Oxidation(+15.99)
M12:Oxidation(+15.99)
M10:Oxidation(+15.99)
S10:Phospho(+79.97)
M7:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99)
M2:Oxidation(+15.99),M7:
Oxidation(+15.99)
M2:Oxidation(+15.99)
S4:Phospho(+79.97)
915.4246
1,828.83
1,829.84
2
0.35
30
46
TRUE
787.9412
867.4437
642.8622
624.9714
765.9069
573.2877
452.2261
460.2052
629.6437
618.7747
614.8184
688.389
558.2893
969.141
936.7974
579.7877
703.3856
767.4326
844.4675
568.9456
564.7799
563.7808
648.848
1,573.87
1,732.87
1,283.71
1,871.89
1,529.80
1,144.56
902.4366
918.3948
1,885.91
1,235.53
1,227.62
687.3812
1,114.56
2,904.40
2,807.37
1,157.56
1,404.76
1,532.85
2,530.38
1,703.81
1,127.54
1,125.55
1,295.68
1,574.86
1,733.87
1,284.72
1,872.90
1,530.80
1,145.57
903.4423
919.4008
1,886.91
1,236.54
1,228.63
688.3881
1,115.57
2,905.40
2,808.37
1,158.57
1,405.76
1,533.85
2,531.38
1,704.82
1,128.55
1,126.55
1,296.68
2
2
2
3
2
2
2
2
3
2
2
1
2
3
3
2
2
2
3
3
2
2
2
6.69
4.95
0.22
1.48
2.74
1.35
2.34
1.97
3.19
0.27
0.23
1.30
0.91
3.58
2.58
0.71
3.85
2.81
3.05
0.84
0.68
0.47
3.23
177
508
1250
579
1095
716
1092
924
968
908
26
260
105
470
451
269
224
224
267
171
300
1349
363
191
523
1260
595
1107
725
1099
930
982
917
36
265
113
494
475
278
235
236
290
184
308
1357
373
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
495.2934
593.8164
578.2946
467.7539
547.317
426.7391
737.7102
884.9423
924.4907
912.9977
889.0017
455.2381
762.897
896.9749
726.915
546.2924
527.2913
825.9612
988.5712
1,185.62
1,154.57
933.4922
1,092.62
851.4625
2,210.11
1,767.87
1,846.97
1,823.98
1,775.99
908.4606
1,523.78
1,791.93
1,451.81
1,090.57
1,052.57
1,649.91
989.5785
1,186.62
1,155.58
934.5
1,093.63
852.4693
2,211.11
1,768.87
1,847.97
1,824.99
1,776.99
909.4682
1,524.78
1,792.94
1,452.82
1,091.58
1,053.57
1,650.91
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
0.59
2.30
1.30
0.11
0.48
1.12
3.05
4.92
4.18
0.82
2.98
0.24
3.39
3.83
3.14
0.08
1.43
2.24
62
42
83
297
416
231
44
94
499
353
731
407
535
872
846
499
643
256
69
51
91
304
426
240
63
109
516
370
746
414
548
892
860
509
650
269
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
871.126
2,610.35
2,611.36
3
2.49
161
184
TRUE
2,244.11
1,041.58
2,014.04
1,644.88
1,680.91
1,451.79
1,485.89
1,614.00
2,101.10
1,024.57
1,235.68
860.5154
1,038.66
1,052.67
1,185.67
1,674.90
2,245.10
1,042.59
2,015.05
1,645.88
1,681.92
1,452.80
1,486.90
1,614.99
2,102.10
1,025.57
1,236.68
861.5233
1,039.66
1,053.68
1,186.68
1,675.90
2
2
3
2
2
2
2
2
3
2
2
2
2
2
2
3
6.05
0.90
2.44
3.44
0.68
0.70
1.18
6.68
2.98
0.39
1.51
0.10
0.15
0.27
0.55
0.53
117
166
181
219
192
187
342
342
261
191
2144
134
834
878
65
854
137
174
196
234
207
199
355
356
280
199
2153
140
842
886
74
868
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
768.4143
948.5084
613.3378
881.4763
702.3269
1,034.48
539.8117
515.3023
509.2961
1,534.81
1,895.00
1,224.66
1,760.94
2,103.96
2,066.95
1,077.61
1,028.59
1,016.58
1,535.82
1,896.00
1,225.67
1,761.94
2,104.96
2,067.95
1,078.62
1,029.59
1,017.58
2
2
2
2
3
2
2
2
2
1.54
4.33
2.12
3.42
1.93
2.20
0.60
2.17
0.94
219
248
43
450
284
265
1449
203
257
231
264
54
465
300
281
1457
211
265
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
FALSE
TRUE
635.337
459.7434
646.8605
684.9119
968.0299
464.2849
589.9691
844.9471
529.3173
417.7457
605.863
503.9603
956.0537
665.8765
664.8767
604.3754
706.4019
500.7934
581.8242
1,394.19
721.3748
460.2398
470.7313
1,902.99
917.4711
1,291.71
1,367.81
1,934.04
926.5542
1,766.88
1,687.88
1,056.62
833.4758
1,209.71
1,508.86
1,910.09
1,329.74
1,327.74
1,206.74
1,410.79
999.5712
1,161.63
2,786.37
1,440.73
918.464
939.447
1,904.00
918.4786
1,292.71
1,368.81
1,935.05
927.5628
1,767.89
1,688.89
1,057.63
834.4837
1,210.72
1,509.86
1,911.10
1,330.74
1,328.74
1,207.74
1,411.79
1,000.58
1,162.64
2,787.37
1,441.74
919.4712
940.4562
3
2
2
2
2
2
3
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
2
2.22
0.31
2.30
4.13
2.04
0.81
0.50
0.24
0.84
0.10
1.75
0.67
2.19
3.33
2.14
1.14
3.57
0.27
3.81
3.74
3.84
0.70
1.45
64
345
372
783
157
880
880
725
678
54
301
266
891
317
471
915
32
74
589
407
1069
262
1040
79
352
382
795
173
887
894
740
686
60
311
279
908
327
481
926
45
83
598
430
1081
268
1046
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
634.3236
849.7618
663.3425
546.2966
480.2619
694.8203
654.8381
965.001
1,266.63
2,546.26
1,987.00
1,090.58
958.5082
1,387.63
1,307.66
1,927.99
1,267.64
2,547.26
1,988.01
1,091.58
959.5164
1,388.63
1,308.67
1,928.99
2
3
3
2
2
2
2
2
0.41
2.84
1.62
0.48
0.41
0.38
1.89
0.04
189
71
272
2
67
1074
1074
994
199
95
289
10
74
1085
1085
1012
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,435.65
Actn1
Alphaactinin1
IPI00209082,IPI00454431
102946
12
14
15
2
1.64
301
312
TRUE
Isoform2ofGelsolin
Phosphatidylinositol4,5bisphosphate3kinasecatalytic
subunitbetaisoform
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
IPI00923716
80911
28
41
122
49.80%
VPFDAATLHTSTAMAAQHGMDDDGTGQK
R
Q
64.3
31.6
2
M6:Oxidation(+15.99),M9:
Oxidation(+15.99)
718.8308
M14:Oxidation(+15.99),M20:
Oxidation(+15.99)
969.1017
1,436.65
Gsn
2,904.28
2,905.27
3
5.43
369
396
TRUE
IPI00208989
122595
5
5
6
6.54%
VPFILTYDFIHVIQQGK
R
T
32.3
23.9
2
673.3762
2,017.11
2,018.11
3
0.62
956
972
TRUE
Pik3cb
Pik3ca
Dnm2
Clip2
Krt75
Myh3
Actn4
Hspa9
Ckap4
Flot1
Irs1
Myh9
Emilin1
Eprs
Purb
Specc1l
Myh9
Irs1
Gsn
Sdpr
Nes
Myo1b
Jup
Htra1
Mybph
Rai14
Rai14
Myo1d
Flot1
Hspa5
Ddb1
Npepps
Nedd4
Myo1c
Akt1
Krt10
Krt10
Krt15
Flii
Myh3
Copb1
Atp5a1
LOC682005;G
apdh;LOC685
186
LOC682005;G
apdh;LOC685
186
Gsn
Myh9
Cltc
Dsp
Myo1d
Smtn
Hsd17b4
Ap3b1
Myh9
Myh10
Krt14
Myo1d
Hspa5
Specc1l
Myo1c
Lmo7
Lmo7
Krt1
LOC682005;G
apdh;LOC685
186
Mprip
Lmo7
Lmo7
Krt5
Npepps
Clip2
Copa
Isoform1ofDynamin2
111kDaprotein
58kDaprotein
Myosin3
Alphaactinin4
Stress70protein,mitochondrial
cytoskeletonassociatedprotein4
Isoform1ofFlotillin1
Insulinreceptorsubstrate1
Myosin9
elastinmicrofibrilinterfacer1
170kDaprotein
TranscriptionalactivatorproteinPurbeta
CytospinA
Myosin9
Insulinreceptorsubstrate1
Isoform2ofGelsolin
Serumdeprivationresponseprotein
Isoform1ofNestin
IsoformCofMyosinIb
Junctionplakoglobin
HtrAserinepeptidase1,isoformCRA_a
53kDaprotein
Isoform2ofAnkycorbin
Isoform2ofAnkycorbin
MyosinId
Isoform1ofFlotillin1
78kDaglucoseregulatedprotein
DNAdamagebindingprotein1
aminopeptidasepuromycinsensitive
neuralprecursorcellexpressed,developmentallydown
regulatedgene4
MyosinIc
RACalphaserine/threonineproteinkinase
Keratin,typeIcytoskeletal10
Keratin,typeIcytoskeletal10
Keratin,typeIcytoskeletal15
FlightlessIhomolog
Myosin3
Coatomersubunitbeta
ATPsynthasesubunitalpha,mitochondrial
L
57.5
29
2
IPI00769069,IPI00769166
124233
IPI00210319,IPI00389749,IPI00389750,I
PI00896218
98232
IPI00476704
111364
IPI00777617
57763
IPI00201578
223846
IPI00213463
104900
IPI00363265
73840
IPI00365982
63529
IPI00208784
47481
IPI00199662
131160
IPI00209113
226326
IPI00199867
107542
IPI00421357,IPI00476855
170072
IPI00189358
33515
IPI00372846
124324
IPI00209113
226326
IPI00199662
131160
IPI00923716
80911
IPI00362416
46368
IPI00194103
208776
IPI00231045,IPI00331979,IPI00391496 124908
IPI00421429
81784
IPI00199325
51312
IPI00557294
52762
IPI00372146
105981
IPI00372146
105981
IPI00207989
116081
IPI00208784
47481
IPI00206624
72331
IPI00324451
127044
IPI00372700
103329
10
11
17
9.93%
VPFVLTQDFLIVISK
R
G
72.2
19
2
860.0104
1,718.01
1,719.01
2
1.94
952
966
TRUE
4
22
2
86
28
9
6
2
30
138
11
9
4
21
138
28
28
5
16
6
9
6
4
29
34
43
3
21
3
6
4
24
2
104
34
9
7
2
42
222
11
9
4
23
222
39
41
6
17
6
9
7
4
35
39
55
3
27
3
6
4
32
3
217
49
19
11
3
108
3511
11
9
4
36
3511
93
122
12
27
8
15
15
5
51
69
272
3
59
3
6
5.28%
22.20%
10.10%
50.30%
39.60%
18.10%
18.40%
5.37%
29.50%
55.70%
15.40%
7.99%
22.70%
25.00%
55.70%
31.30%
49.80%
14.60%
10.50%
7.33%
14.10%
18.10%
14.40%
36.10%
39.20%
47.00%
6.78%
39.60%
4.47%
8.26%
VPVGDQPPDIEYQIK
VQELEGLDVEYR
VQFIEQQNK
VQLLHTQNTSLIHTK
VQQLVPK
VQQTVQDLFGR
VQSLQAAVGTFESILR
VQVQVVER
VREQQQQQQQQQQSSLHPPEPK
VRTELADK
VSEILSALER
VSESVVFTDTNSILR
VSEVKPSYR
VSGISKPQTVEK
VSHLLGINVTDFTR
VSLPR
VSNSGGSMSVSLVADENPFAQSALR
VSPLSFGR
VSQDSLGSLAEENVQPLR
VSTTLNVAQAYYAR
VSVELTNSLFK
VTAGISFAIPSDK
VTAVNSAGAGPPAVLDQPVHIQEITEAPK
VTDEDVDALK
VTDEDVDALKQDLQR
VTDGMFLEALNSK
VTGEVLDILSR
VTHAVVTVPAYFNDAQR
VTLGTQPTVLR
VTLSFPSTLQTGTGTLK
K
R
K
R
K
K
K
R
R
R
R
R
R
K
K
K
K
K
K
K
R
K
R
R
R
K
K
K
K
K
D
G
V
K
R
A
S
A
S
V
R
Y
N
S
G
T
S
K
Y
D
H
I
I
Q
A
L
L
Q
T
I
45.2
83.8
43.2
35.8
31.8
72
100
64.3
59.8
39.6
75
68.6
40.5
48.3
95.6
28.7
132
30.6
70.7
67.6
71.7
64.1
26.3
50
113
93.9
63.8
58.2
56.3
28.4
28.6
28.5
28.2
24.9
19.9
28.3
25.5
23.8
29.5
28.2
26.9
28.2
26.4
26.3
27.2
22.4
30.2
28
28.2
28.1
26.5
27
26
28.1
29.7
29.2
26.6
28.7
24.5
25.2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
849.4451
725.3663
567.3018
433.9981
406.256
645.8452
859.9789
478.7807
886.1125
466.2648
558.8189
833.9407
532.791
636.8618
786.431
571.3565
1,270.12
431.7432
971.5039
778.9089
618.8461
653.358
970.5177
552.7753
872.942
720.8566
601.3444
944.4902
592.856
875.9868
1,696.87
1,448.72
1,132.59
1,731.96
810.4964
1,289.67
1,717.94
955.5458
2,655.31
930.514
1,115.62
1,665.87
1,063.57
1,271.71
1,570.85
570.3487
2,538.22
861.4708
1,940.99
1,555.80
1,235.68
1,304.70
2,908.53
1,103.54
1,743.87
1,439.70
1,200.67
1,886.96
1,183.70
1,749.96
1,697.88
1,449.72
1,133.60
1,732.97
811.5042
1,290.68
1,718.94
956.5529
2,656.32
931.5213
1,116.63
1,666.87
1,064.57
1,272.72
1,571.85
571.3568
2,539.21
862.4787
1,941.99
1,556.81
1,236.68
1,305.71
2,909.54
1,104.54
1,744.87
1,440.70
1,201.68
1,887.97
1,184.70
1,750.96
2
2
2
4
2
2
2
2
3
2
2
2
2
2
2
1
2
2
2
2
2
2
3
2
2
2
2
2
2
2
4.12
1.63
0.25
1.39
0.05
1.45
3.43
0.74
0.89
0.56
3.10
5.15
0.15
0.45
0.29
0.47
6.31
0.10
5.99
1.83
0.43
2.09
0.14
0.14
2.33
0.70
1.35
0.60
3.02
3.65
143
698
160
1714
626
395
141
254
869
1267
494
42
252
14
374
1022
252
291
920
336
664
347
153
497
497
466
393
165
629
130
157
709
168
1728
632
405
156
261
890
1274
503
56
260
25
387
1026
276
298
937
349
674
359
181
506
511
478
403
181
639
146
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
IPI00876592
IPI00393867
IPI00212844
IPI00421806,IPI00551673
IPI00421806,IPI00551673
IPI00370090
IPI00211698
IPI00201578
IPI00211812
IPI00396910
11
50
6
14
13
2
7
86
14
4
11
72
8
23
22
2
7
104
14
4
12
328
16
342
362
2
10
217
15
6
19.00%
48.80%
16.00%
21.50%
21.50%
12.50%
6.77%
50.30%
20.80%
9.58%
VTLYDPMSGVLTSVQTK
VTMESALTAR
VTMNEFEYLK
VTMQNLNDR
VTMQNLNDR
VTMQNLNDRLASYLDKVR
VTQTLQPTLYQIR
VTVETEDNR
VTVNTNVTDLNDYLQHILK
VVDALGNAIDGK
R
R
R
K
K
K
K
K
K
R
T
D
L
L
L
A
T
T
S
G
65.9
90.6
49.9
70.8
55.2
35.6
60.7
50.7
33.1
78.9
28.7
27.9
28.7
27.8
28.5
28.3
24.6
28
26.4
27.4
2
2
2
2
2
2
2
2
2
2
927.9824
547.7797
645.3106
553.7672
545.7697
718.0452
780.944
531.7578
734.0629
586.322
1,853.95
1,093.54
1,288.61
1,105.52
1,089.52
2,151.11
1,559.87
1,061.50
2,199.17
1,170.63
1,854.95
1,094.55
1,289.61
1,106.53
1,090.53
2,152.12
1,560.88
1,062.51
2,200.16
1,171.63
2
2
2
2
2
3
2
2
3
2
2.52
0.03
3.63
0.03
0.03
0.64
3.23
0.95
5.29
3.16
105
15
145
147
147
96
1049
60
853
150
121
24
154
155
155
113
1061
68
871
161
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
630.304
1,258.59
1,259.60
2
1.04
322
332
TRUE
694.827
549.304
462.7508
677.3486
557.3118
423.7766
492.2858
578.3464
664.0221
561.7996
762.9263
584.3278
629.8848
596.322
637.7963
423.2356
624.7672
688.8577
738.3787
1,387.64
1,096.59
923.486
1,352.68
1,112.61
845.5375
982.556
1,154.68
1,989.04
1,121.58
1,523.84
1,166.64
1,257.75
1,190.63
1,273.58
844.4556
1,247.52
1,375.70
1,474.74
1,388.64
1,097.60
924.4943
1,353.68
1,113.62
846.5454
983.5639
1,155.69
1,990.05
1,122.59
1,524.84
1,167.65
1,258.76
1,191.64
1,274.58
845.4633
1,248.53
1,376.71
1,475.75
2
2
2
2
2
2
2
2
3
2
2
2
2
2
2
2
2
2
2
1.52
0.59
0.55
4.36
0.14
0.10
0.09
0.07
1.92
0.47
1.55
0.70
0.46
1.10
0.70
0.12
1.53
1.00
0.03
322
2
712
177
2473
701
476
11
1028
546
386
473
296
465
808
763
916
754
211
333
10
718
188
2482
707
484
23
1046
555
399
482
307
474
817
769
924
766
222
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
1,147.03
826.9254
750.8657
438.2174
602.3226
721.8538
518.7695
651.8485
2,292.04
1,651.84
1,499.72
874.4192
1,202.63
1,441.69
1,035.52
1,301.68
2,293.03
1,652.84
1,500.72
875.4265
1,203.64
1,442.69
1,036.53
1,302.68
2
2
2
2
2
2
2
2
4.22
2.02
0.84
0.67
0.07
5.70
0.32
6.50
85
608
827
352
196
174
554
551
105
620
839
358
205
186
562
562
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
441.2412
896.9937
533.7623
785.3975
838.3953
504.7539
780.4149
576.3018
590.3037
597.7921
629.8588
637.8536
880.4667
1,791.97
1,065.51
1,568.78
837.3875
1,007.49
779.407
1,150.59
1,178.59
1,193.57
1,257.70
1,273.69
881.4734
1,792.97
1,066.52
1,569.78
838.3947
1,008.50
780.4144
1,151.59
1,179.60
1,194.58
1,258.70
1,274.70
2
2
2
2
1
2
1
2
2
2
2
2
1.29
5.40
0.19
2.44
0.70
0.14
0.60
0.77
1.21
0.64
3.81
0.26
227
262
257
462
1796
211
167
376
349
361
765
721
233
279
264
474
1801
218
172
385
358
370
775
731
TRUE
TRUE
FALSE
TRUE
TRUE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
453.756
932.932
497.2539
905.4964
1,863.85
992.4922
906.505
1,864.85
993.5006
2
2
2
0.77
1.92
0.52
260
154
237
266
168
244
TRUE
TRUE
TRUE
102739
119797
55719
56489
56489
48854
144843
223846
106996
59737
M8:Oxidation(+15.99)
M5:Oxidation(+15.99)
M7:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99)
M3:Oxidation(+15.99)
M5:Oxidation(+15.99),M8:
Oxidation(+15.99)
IPI00555252,IPI00567177
35810
8
9
16
27.90%
VVDLMAYMASK
R
62.8
28.9
2
IPI00555252,IPI00567177
IPI00923716
IPI00209113
IPI00193983
IPI00366081
IPI00207989
IPI00361871,IPI00561311
IPI00326948,IPI00561647
IPI00360117
IPI00209113
IPI00391300
IPI00421855
IPI00207989
IPI00206624
IPI00372846
IPI00393867
IPI00421345
IPI00421345
IPI00421857
35810
80911
226326
191585
332383
116081
99862
81072
121486
226326
233603
52667
116081
72331
124324
119797
156634
156634
64814
9
17
113
27
18
44
9
3
2
111
58
8
42
19
11
50
35
44
8
12
22
179
29
18
55
9
3
2
172
67
12
53
20
11
72
43
55
13
51
86
1862
29
28
144
13
5
2
2414
363
90
149
52
19
328
112
141
278
34.80%
33.80%
50.90%
21.50%
7.79%
47.80%
10.50%
4.79%
2.74%
50.00%
40.00%
26.80%
45.40%
33.50%
12.50%
48.80%
30.80%
38.90%
12.20%
VVDLMAYMASKE
VVEHPEFLK
VVFQEFR
VVGAMQLYSVDR
VVIVDPETNK
VVLFLQK
VVLPTGNQR
VVLVTGAGGGLGR
VVNVANLGAVPSSQDNIHR
VVQEQGTHPK
VVSSVLQFGNISFK
VVSTHEQVLR
VVSVIAELLSTK
VYEGERPLTK
VYNYMNAVER
WAAQTIR
WAWDQEEER
WDVSGISVASVEK
WELLQQVDTSTR
R
M
R
R
R
R
R
R
K
K
K
K
K
K
R
K
R
K
K
A
Q
K
E
V
A
A
F
F
K
T
A
D
D
R
R
G
T
78.2
43.6
46.7
43.9
32
35.6
45.5
81
27.6
52.4
91.3
70.4
97.7
40.8
46.5
34.3
40.2
91.3
90.7
29.6
25.5
27.9
29
26.9
16.5
21.8
24.9
27.4
27.8
25.3
25.9
19.9
27.2
28.1
27.9
28
28.7
28.6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Glyceraldehyde3phosphatedehydrogenase
258kDaprotein
LMO7b
LMO7b
Keratin,typeIIcytoskeletal5
aminopeptidasepuromycinsensitive
111kDaprotein
Copaprotein
IPI00555252,IPI00567177
IPI00392930
IPI00421345
IPI00421345
IPI00382153
IPI00372700
IPI00476704
IPI00372458
35810
257845
156634
156634
61809
103329
111364
138346
9
40
44
44
23
6
29
4
12
51
55
55
31
6
34
4
51
83
141
141
674
6
49
4
34.80%
21.50%
38.90%
38.90%
31.10%
8.26%
32.40%
4.41%
WGDAGAEYVVESTGVFTTMEK
WHQVETTPLREEK
WIDTTSGIYSTEK
WQDDLAK
WTLLQEQGTK
YAAVTQFEATDAR
YAQEVADLK
YAVTTGDHGIIR
K
R
K
K
K
R
K
K
A
Q
S
W
T
R
A
T
70.6
39.9
72.6
37.7
57.4
70.3
57.4
56.2
31.4
29.1
29.6
25.2
28.7
29.4
26.8
28
2
2
2
2
2
2
2
2
8
14
2
43
37
2
10
10
4
21
57
119
11
14
2
50
49
2
12
13
6
27
66
194
38
15
3
62
105
2
27
264
52
711
435
3095
30.50%
20.80%
11.40%
48.90%
19.50%
11.80%
24.50%
16.20%
15.90%
29.00%
39.20%
51.60%
YDITTLR
YEAAGTLVTLSSAPTAIK
YEDEINKR
YEEAMKEVLSVQK
YEEEIR
YEEEVALR
YEEIVK
YEELQITAGK
YEELQITAGR
YEELQQTAGR
YEILTPNAIPK
YEILTPNSIPK
K
K
K
K
R
R
R
K
K
K
R
R
S
A
T
Q
C
A
E
H
H
H
G
G
40.6
85.2
37.5
65.5
27.9
46.5
34.5
67.1
80.9
80.3
37.5
65.1
25.3
25.5
27.1
29.2
24.6
26.8
25.3
28.5
28
27.6
26.5
27.6
2
2
2
2
2
2
2
2
2
2
2
2
17
13
13
26
16
20
111
23
283
43.90%
21.80%
21.50%
YEINVLR
YEMEETEVVITSYQK
YENEVALR
K
R
K
N
N
Q
50.7
79.1
57.2
25.5
30.5
27.5
2
2
2
IPI00769069,IPI00769166
124233
IPI00471584
83266
IPI00471584
83266
IPI00421791
50196
IPI00421797
50657
IPI00627068
75469
IPI00198498,IPI00198520,IPI00558156,I
PI00777920
52664
IPI00471584
83266
15
25
25
3
4
3
17
26
26
5
5
3
28
38
38
19
10
3
18.40%
37.00%
37.00%
19.70%
12.30%
6.01%
YEQYLDNLLVR
YESLTDPSK
YESLTDPSKLDSGK
YETELNLR
YETEVSLR
YGEPGEVFINK
K
R
R
K
K
K
F
L
E
M
Q
G
63.7
40.1
42
37.1
42.7
56.6
27.9
27.8
29.5
27.8
27.6
28.7
2
2
2
2
2
2
713.3742
520.2524
770.3834
519.2678
498.7542
626.8151
1,424.73
1,038.49
1,538.75
1,036.52
995.4928
1,251.61
1,425.74
1,039.49
1,539.75
1,037.53
996.5002
1,252.62
2
2
2
2
2
2
1.91
2.15
3.04
0.86
0.47
0.81
641
56
56
183
186
312
651
64
69
190
193
322
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
2
25
2
26
2
38
4.66%
37.00%
YGLFPANYVELR
YHTSQSGDEMTSLSEYVSR
R
R
M
50.1
46.4
27.3
30.3
2
2
721.3798
731.655
1,440.74
2,191.94
1,441.75
2,192.94
2
3
2.65
4.08
460
457
471
475
TRUE
TRUE
IPI00188059
IPI00471584
IPI00366081
IPI00923716
4
15
10
17
4
15
10
22
4
29
27
86
12.00%
24.60%
4.07%
33.80%
YHVPVVVVPEGSASDTQEQAILR
YIDQEELNK
YIELLTR
YIETDPANR
R
K
R
R
L
T
S
D
58.2
52.6
39.5
51.6
27.4
28.3
23
27.3
2
2
2
2
832.1059
576.2833
454.2666
539.7623
2,493.29
1,150.55
906.5176
1,077.51
2,494.29
1,151.56
907.5254
1,078.52
3
2
2
2
3.20
0.14
0.11
0.19
267
276
1010
679
289
284
1016
687
TRUE
TRUE
TRUE
TRUE
Tnnt2
Cald1
Krt10
Isoform2ofTroponinT,cardiacmuscle
Caldesmon
Keratin,typeIcytoskeletal10
similartoPhosphatidylinositol4,5bisphosphate3kinase
catalyticsubunitalphaisoform(PI3kinasep110subunit
alpha)(PtdIns3kinasep110)(PI3K)isoform3
HeatshockproteinHSP90beta
HeatshockproteinHSP90beta
Keratin,typeIcytoskeletal42
TypeIhairkeratinKA30
Splicingfactorproline/glutaminerich
Rpn2
Hsp90ab1
Dsp
Gsn
R
Glyceraldehyde3phosphatedehydrogenase
Isoform1ofTroponinT,fastskeletalmuscle
Coatomersubunitbeta
Keratin,typeIIcytoskeletal1b
Isoform2ofAnkycorbin
258kDaprotein
TypeIIkeratinKb25
Elongationfactor1alpha1
Keratin,typeIIcytoskeletal1
Keratin,typeIIcytoskeletal6A
Keratin,typeIIcytoskeletal5
234kDaprotein
Myosin9
Cttn
Hsp90ab1
VPENTMQAMQQK
Glyceraldehyde3phosphatedehydrogenase
Isoform2ofGelsolin
Myosin9
Clathrinheavychain1
similartodesmoplakinisoformIisoform2
MyosinId
smoothelin
Hsd17b4protein
adaptorrelatedproteincomplex3,beta1subunit
Myosin9
234kDaprotein
Keratin,typeIcytoskeletal14
MyosinId
78kDaglucoseregulatedprotein
CytospinA
MyosinIc
LMO7b
LMO7b
Keratin,typeIIcytoskeletal1
Tnnt3
Copb1
Krt77
Rai14
Mprip
Krt85
Eef1a1
Krt1
LOC683313
Krt5
Myh10
Myh9
Pik3ca
Hsp90ab1
Hsp90ab1
Krt42
Krt35
Sfpq
30.40%
CortactinisoformC
HeatshockproteinHSP90beta
Dolichyldiphosphooligosaccharideprotein
glycosyltransferasesubunit2
HeatshockproteinHSP90beta
similartodesmoplakinisoformIisoform2
Isoform2ofGelsolin
IPI00554262,IPI00560341,IPI00829459,I
PI00829466,IPI00829504,IPI00829511 30734
IPI00211812
106996
IPI00454475
57238
IPI00372146
105981
IPI00392930
257845
IPI00200792,IPI00421785
55803
IPI00195372,IPI00551729
50096
IPI00421857
64814
IPI00393340
59233
IPI00382153
61809
IPI00391300
233603
IPI00209113
226326
IPI00231332,IPI00231812,IPI00561761,I
PI00776952,IPI00780763
34435
IPI00208118
60567
IPI00421806,IPI00551673
56489
69060
83266
332383
80911
M5:Oxidation(+15.99),M8:
Oxidation(+15.99)
M5:Oxidation(+15.99)
M5:Oxidation(+15.99)
M19:Oxidation(+15.99)
M5:Oxidation(+15.99)
M3:Oxidation(+15.99)
M10:Oxidation(+15.99)
IPI00194087
IPI00391300,IPI00367479,IPI00558912
IPI00194087
IPI00194087
IPI00391300
IPI00206624
IPI00382153
IPI00210566
IPI00391300
IPI00367479,IPI00558912
IPI00370090,IPI00370073,IPI00421855
IPI00370090,IPI00421855,IPI00421793
IPI00370090,IPI00421855,IPI00421793
IPI00421857,IPI00382153,IPI00551558
IPI00780672,IPI00454476
IPI00777617
IPI00367479
IPI00210566
IPI00210566
IPI00210566
Arhgef2
Myo1d
Irs1
Rhoguaninenucleotideexchangefactor2
MyosinId
Insulinreceptorsubstrate1
Irs1
Eno1
Mprip
Lmo7
RGD1563532
Myo1b
Myo1c
9Sep
Centg2
Tubb2a
Tubb5
Tubb6
Ddx3x
Myh9
Myo1d
Specc1l
Myo1c
Specc1l
Htra1
Hnrnpu
Myo1b
Insulinreceptorsubstrate1
IPI00199662
Alphaenolase
IPI00464815,IPI00767147
258kDaprotein
IPI00392930
LMO7b
IPI00421345
86kDaprotein
IPI00568788,IPI00768137
IsoformCofMyosinIb
IPI00231045,IPI00331979,IPI00391496
MyosinIc
IPI00393867
septin9isoform1
IPI00215235,IPI00782707
centaurin,gamma2
IPI00389524
Tubulinbeta2Achain
IPI00475639
Isoform1ofTubulinbeta5chain
IPI00197579
Tubulin,beta6
IPI00195673
DEAD(AspGluAlaAsp)boxpolypeptide3,Xlinked IPI00362534
Myosin9
IPI00209113
MyosinId
IPI00207989
CytospinA
IPI00372846
MyosinIc
IPI00393867
CytospinA
IPI00372846
HtrAserinepeptidase1,isoformCRA_a
IPI00199325
SP120
IPI00210090,IPI00566967
IsoformCofMyosinIb
IPI00231045,IPI00331979,IPI00391496
Serine/threonineproteinphosphatasePP1betacatalytic
subunit
IPI00203390
Actin,alphaskeletalmuscle
IPI00189813
Actin,alphaskeletalmuscle
IPI00189813
Isoform2ofAnkycorbin
IPI00372146
Isoformp85alphaofPhosphatidylinositol3kinaseregulatory
subunitalpha
IPI00211946
Phosphatidylinositol3kinase,regulatorysubunit,
polypeptide2,isoformCRA_a
IPI00554334
Tropomodulin1
IPI00189723,IPI00421889
tropomyosin1,alphaisoformc
IPI00210945
tropomyosin1,alphaisoformc
IPI00210945
Isoform2ofTropomyosinbetachain
IPI00187731
Isoform2ofTropomyosinbetachain
IPI00187731
111kDaprotein
IPI00476704
tropomyosin1,alphaisoformc
IPI00210945
Isoform1ofTropomyosinbetachain
IPI00230775
111kDaprotein
IPI00476704
similartocoronin,actinbindingprotein,2B
IPI00373332
RCG61183,isoformCRA_b
IPI00362106
HeatshockproteinHSP90alpha
IPI00210566
Elongationfactor1alpha1
IPI00195372,IPI00551729
Ppp1cb
Acta1
Acta1
Rai14
Pik3r1
Pik3r2
Tmod1
Tpm1
Tpm1
Tpm2
Tpm2
Clip2
Tpm1
Tpm2
Clip2
Coro2b
Fermt2
Hsp90aa1
Eef1a1
IPI00368617
IPI00207989
IPI00199662
111895
116081
131160
9
42
31
9
51
39
9
135
145
13.30%
46.20%
31.80%
YIFTSLDKPSVVSLQNLIVR
YIMQYIAAITNPSQR
YIPGATMGTSPALTGDEAAGAADLDNR
K
K
R
D
A
F
33
82.3
95.9
19.1
29.4
31.5
2
2
2
131160
47111
257845
156634
85638
124908
119797
64850
96839
49889
49653
50041
73130
226326
116081
124324
119797
124324
51312
87731
124908
30
7
40
45
5
3
42
3
5
2
13
6
11
122
42
21
40
21
3
5
6
42
7
54
54
5
3
59
3
5
2
15
6
11
194
51
23
53
23
3
5
6
108
10
117
120
5
3
381
3
18
7
45
10
20
2067
135
36
252
36
4
7
8
29.50%
23.70%
19.90%
37.60%
7.64%
3.99%
43.80%
6.42%
5.23%
27.60%
37.80%
33.10%
19.30%
51.90%
46.20%
25.00%
44.00%
25.00%
6.46%
6.64%
7.33%
YIPGATMGTSPALTGDEAAGAADLDNR
YITPDQLADLYK
YKDIYTELSIAK
YLDEELMVLNSNSISLTSR
YLENPNALTER
YLGLLENVR
YLGLMENLR
YLQEEVNINR
YLTGTYVQEESPEGGR
YLTVAAIFR
YLTVAAVFR
YLTVATVFR
YLVLDEADR
YLYVDK
YMDINFDFK
YMDLAENAR
YMDVQFDFK
YMELEQR
YNFIADVVEK
YNILGTNTIMDK
YNYLSLDSAK
R
R
K
K
K
R
K
K
R
R
R
R
K
K
K
R
K
R
K
K
R
F
S
A
E
E
V
V
K
F
G
G
G
M
N
G
F
G
Y
I
M
V
74.6
33.4
51.1
100
53.4
47.2
51.4
48.7
103
68.8
73.1
66.4
47.1
39.2
48.1
36.1
53.5
34.7
54.8
58.5
36.8
31.7
28.4
26.9
30
28
25.5
28.5
28.5
30.3
22
24.4
24
27.5
25.6
27.9
27.4
27.9
27.2
26.7
28.9
28.3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
764.7734
M3:Oxidation(+15.99)
892.9569
M7:Oxidation(+15.99)
1,326.12
M7:Oxidation(+15.99),S10:
Phospho(+79.97)
911.0733
720.3767
722.3919
M7:Oxidation(+15.99)
1,100.55
660.3356
538.811
M5:Oxidation(+15.99)
562.7929
639.3297
893.4193
527.309
520.3021
535.307
547.2802
800.4197
M2:Oxidation(+15.99)
604.7692
M2:Oxidation(+15.99)
549.7481
M2:Oxidation(+15.99)
604.7692
M2:Oxidation(+15.99)
492.7262
599.3129
M10:Oxidation(+15.99)
699.8536
587.294
2,291.30
1,783.90
2,650.23
2,292.30
1,784.90
2,651.23
3
2
2
3.48
3.10
4.11
511
114
489
530
128
515
TRUE
TRUE
TRUE
2,730.20
1,438.74
1,442.77
2,199.08
1,318.66
1,075.61
1,123.57
1,276.64
1,784.82
1,052.60
1,038.59
1,068.60
1,092.54
799.4119
1,207.52
1,097.48
1,207.52
983.4368
1,196.61
1,397.69
1,172.57
2,731.19
1,439.74
1,443.77
2,200.08
1,319.66
1,076.61
1,124.58
1,277.65
1,785.83
1,053.61
1,039.59
1,069.60
1,093.55
800.4195
1,208.53
1,098.49
1,208.53
984.4461
1,197.62
1,398.69
1,173.58
3
2
2
2
2
2
2
2
2
2
2
2
2
1
2
2
2
2
2
2
2
4.26
2.06
1.63
3.96
2.90
3.44
0.36
1.94
0.57
0.50
2.27
1.41
0.41
0.28
0.64
0.52
0.64
1.45
2.07
3.87
0.97
489
270
2177
967
551
618
629
381
167
310
310
310
343
9
165
496
182
489
169
499
232
515
281
2188
985
561
626
637
390
182
318
318
318
351
14
173
504
190
495
178
510
241
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
37170
42034
42034
105981
4
2
2
21
5
3
3
24
5
8
8
32
16.20%
52.80%
52.80%
26.60%
YPENFFLLR
YPIEHGIITNWDDMEK
YPIEHGIITNWDDMEK
YQQAQEEIMK
K
K
K
K
G
I
I
L
43.9
41.4
42.6
60.7
27
30.1
30.2
29.1
2
2
2
2
599.8192
988.9602
980.9627
642.301
1,197.62
1,975.90
1,959.91
1,282.59
1,198.63
1,976.91
1,960.91
1,283.59
2
2
2
2
3.60
2.98
3.01
0.03
113
71
71
571
121
86
86
580
TRUE
FALSE
FALSE
TRUE
83516
10
11
19
17.10%
YQQDQVVKEDNIEAVGK
K
K
29.3
29.5
2
654.999
1,961.97
1,962.98
3
1.95
431
447
TRUE
81251
40464
32831
32831
32941
32941
111364
32831
32820
111364
54948
77861
84800
50096
26
4
33
25
4
5
18
25
21
30
5
2
5
10
30
5
59
40
5
6
18
40
37
33
6
2
5
12
71
5
252
228
14
13
21
228
167
42
8
2
5
27
47.90%
15.00%
65.10%
48.90%
74.30%
71.80%
17.90%
48.90%
70.40%
33.70%
12.30%
3.82%
23.20%
24.50%
YQQDQVVKEDSVEAVGAQLK
YRDLDEDEILGALTEEELR
YSEALKDAQEK
YSEALKDAQEKLELAEK
YSESVKDAQEK
YSESVKDAQEKLEQAEK
YSLIDPASAPELLR
YSQKEDKYEEEIK
YSTKEDKYEEEIK
YVGETDFAK
YYEISTEKPYLSYLMEFR
YYSFFDLNPK
YYTSASGDEMVSLK
YYVTIIDAPGHR
K
K
K
K
K
K
R
K
K
R
R
K
R
K
V
T
L
K
L
K
L
V
L
G
S
Y
D
D
51.8
36.5
57.5
35.6
60
58.1
60.8
69.2
57.3
38.1
55.4
49.8
61.3
67.4
28.6
30.2
28.8
27.7
28.6
29.5
27.1
29.7
30
26.7
30.7
28.2
29.3
28
2
2
2
2
2
2
2
2
2
2
2
2
2
2
745.384
760.3766
641.3212
655.6795
642.3101
661.3302
772.9207
844.908
831.3991
515.2484
783.3792
647.3134
783.856
468.9144
2,233.13
2,278.11
1,280.63
1,964.02
1,282.60
1,980.97
1,543.83
1,687.80
1,660.78
1,028.48
2,347.11
1,292.61
1,565.70
1,403.72
2,234.13
2,279.10
1,281.63
1,965.02
1,283.61
1,981.97
1,544.83
1,688.80
1,661.79
1,029.49
2,348.12
1,293.62
1,566.70
1,404.73
3
3
2
3
2
3
2
2
2
2
3
2
2
3
2.59
4.14
1.36
2.38
0.41
1.62
0.66
3.64
0.57
0.44
2.46
2.58
2.91
0.03
422
10
60
60
60
60
938
214
214
238
297
276
466
85
441
28
70
76
70
76
951
226
226
246
314
285
479
96
TRUE
TRUE
TRUE
TRUE
FALSE
FALSE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
TRUE
M14:Oxidation(+15.99)
M9:Oxidation(+15.99)
M15:Oxidation(+15.99)
M10:Oxidation(+15.99)
IPI00194087
IPI00194087
IPI00197888
IPI00197888
IPI00230775
IPI00230775
IPI00197888