RESIDENT PUBLICATIONS AND ACCOMPLISHMENTS YEAR 2011-2012 Residents Accepted to Fellowships Joseph A. DelTondo, DO, Forensic pathology, Office of the Medical Examiner of Allegheny County, Pittsburgh, PA, July 2012. Jordan E. Olson, MD, Blood Bank/Transfusion Medicine, Penn State Hershey Medical Center, Hershey, PA, July 2012. Jennifer A. Bennett, MD, Neuropathology, University of Pennsylvania, Philadelphia, PA, July 2013. Kael V. Mikesell, DO, Blood Bank/Transfusion Medicine, Penn State Hershey Medical Center, Hershey, PA, July 2013. Peer Reviewed Journal Articles Guttenplan JB, Kosinska W, Zhao ZL, Chen KM, Aliaga C, DelTondo J, Cooper T, Sun YW, Zhang SM, Jiang K, Bruggeman R, Sharma AK, Amin S, Ahn K, El-Bayoumy K. Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. Int J Cancer. 2012 Jun 15;130(12):2783-90. Epub 2011 Nov 19. PMID: 21815141 Welsch MJ, Troiani BM, Hale L, DelTondo J, Helm KF, Clarke LE. Basal cell carcinoma characteristics as predictors of depth of invasion. J Am Acad Dermatol. 2012 Jul;67(1):47-53. Epub 2012 Apr 14. PMID: 22507669 Gammon B, Ali L, Guitart J, Gerami P. Homogeneous staining regions for cyclin D1, a marker of poor prognosis in malignant melanoma Am J Dermatopathol (accepted for publication). Edwards NC, Hing ZA, Blaisdell A, Kopelman DB, Fathke R, Plum W, Newell J, et al. Characterization of coding synonymous and nonsynonymous variants in ADAMS13 using ex vivo and in silico approaches. PLoS ONE 7(6): e38864. Epub 2012 Jun 29 (electronic). PMID: 22768050 Lynch MC, Straub R, Adams DR. Eruptive squamous cell carcinomas with keratoacanthoma-like features in patient treated with sorafenib. J Drugs Dermatol 2011 Mar; 10(3): 308-10. PMID: 21369650. Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, et al. MyD88 provides a protective role in long-term radiation-induced lung injury. Int J Radiat Biol 2012 Apr; 88(4): 335-47. Epub 2012 Feb 6. PMID: 22248128 Yang X, Walton W, Cook DN, Hua X, Tilley S et al. The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 2011 Jul; 45(1): 127-35. Epub 2013 Sep 24. PMID: 20870892 Ely A, Evans J, Sundstrom J, Malysz J, Specht C, Wilkinson M. Orbital involvement in extra nodal natural killer T cell lymphoma: an atypical case presentation and review of the literature. Orbit (accepted for publication). Adil E, Setabutr D, Mikesell K, Goldenberg D. Hyalinizing clear cell adenocarcinoma of the oropharynx. Head Neck (accepted for publication). Peer Reviewed Journal Articles, Submitted Yang X, Walton W, Cook DN, Carlso M, Bricke J, Ting JP, Blackstock W, Kirby SL. Th17 cells mediate radiation-induced pulmonary fibrosis. Am J Pathol, submitted Ohanessian S, et al., Dedifferentiated epithelial-myoepithelial carcinoma: Analysis of a rare entity based on a case report and literature review, submitted Lynch MC, Graber EM, Johnson TS, Clarke LE. Epithelioid sarcoma resembling benign fibrous histiocytoma, Cutis, submitted. Published Abstracts Timek D, Housman C, Wilkinson M, Specht C. Massive gliosis of the retina – A Muller cell proliferation or an intraocular ependymoma? J. Neuropathol Exp Neurol 70: 514 (60), 2011. Mikesell K, Housman C, Sheehan J, Specht C. Ependymosarcoma: Light and Electron Microscopic Study of a Case. J. Neuropathol Exp Neurol 70: 514 (61), 2011. Bennett JA, Jatavallabhula N, Choudhary A, Dias M, Baccon JW. Cystic atypical choroid plexus papilloma with a markedly elevated mitotic rate in an infant. J Neuropathol Exp Neurol 70(6): 546, 2011. Evans J, Greiner R, Iantosca M, Specht C. Primary central nervous system lymphoma in an adolescent: A rare presentation of acquired immunodeficiency syndrome (AIDS). J. Neuropathol Exp Neurol 70: 541 (162), 2011. George, MR, Castellani, WJ, Nifong, TP, Ehmann, C, Wells, JM, Domen, RE, Shike H, Welch, T, Bears, L. “Technical aspects of therapeutic leukapheresis in CML during pregnancy” (poster presentation) 2011 AABB Annual Meeting, San Diego, CA, October, 2011 Bennett JA, Mani H. The Impact of Immunohistochemistry on Turn-aroundTimes in Surgical Pathology Reporting. (USCAP) Modern Pathol 2012 Feb; 25(S2): 495A, 2012. Newell J.M, Patrick S., Clawson G.A.: RNA quality analysis of tumor bank specimens and downstream applicability. ASIP Annual Meeting (San Diego, CA) FASEB J. March 29, 2012 26:1034.15 2 Wells J, Housman C, Weinstein J., Liang D, Specht C. Peters’ Anomaly with Multiple Congenital Malformations: Light and Electron Microscopic Study of a case. J Neuropathol Exp Neurol 2012; 71: 561 (50), 2012. Riley M, Millington K, Dias M, Choudhary A, Specht C. Choristoma of the trochlear nerve in a 5 month old child: Clinical features and Light microscopic study of a case. J Neuropathol Exp Neurol 2012; 71: 593 (170), 2012. Wells J, Zalatimo O, Housman C, Iantosca M, Specht C. Light Microscopic and Ultrastructural Findings in a Case of Intraventricular Schwannoma. (poster presentation) J Neuropathol Exp Neurol 2012; 71: 596 (179.) Oral Presentations at Scientific Meetings Ali L, Talamo G, Clarke LE, Helm KF, Bayerl MG, Malysz J. Cutaneous Involvement of Plasma Cell Neoplasms. 48th Annual Meeting of the American Society of Dermat opathology (ASDP), Seattle, Washington, October 20-23, 2011. [Study done at Hershey Medical Ctr in collaboration with Myeloma Oncology Group at Cancer Ctr] England MR, Lokhandwala PM, Ropson IJ, Dalessio PM, Craven RC. Nucleation of retroviral capsid maturation: probing the role of basic residues in the interdomain interface. Am Soc Virol; Minneapolis, MN, Jul 2011. Wilkinson LA, Bayerl M. Case #266 Post-infectious mononucleosis T-cell proliferation complicated by hemophagocytic syndrome. Eur Assoc Hematopathology Workshop T-cell neoplasms and their mimics; Viral Session. Lisbon, Portugal, 2012. [Presented by moderator]. Poster Presentations George MR, Nifong TP, Ehmann C, Wells JM, Shike H, Domen RE, Welch TL, Bears LR, Castellani WJ. Technical Aspects of Therapeutic Leukapheresis in CML during Pregnancy. AABB Annual Meeting, San Diego, CA, October 22-25, 2011. Ali, L. Disseminated histoplasmosis with cutaneous lesions. 48th Annual Meeting Am Soc Dermatopathology (ASDP), Seattle, Washington, October 20-23, 2011. Ali, L. Metastatic cutaneous meningioma of scalp. 48th Annual Meeting ASDP, Seattle, WA, October 20-23, 2011. Ali, L. CD 20 expression in lupus, dermatitis and lichen planus. 48th Annual Meeting ASDP, Seattle, WA, October 20-23, 2011. Ali, L. Cutaneous metastases of well-differentiated neuroendocrine tumors; a case series of four lesions presenting as the 1st sign of visceral malignancy; well-differentiated neuroendocrine tumors; metastatic involvement of skin is a sign of internal malignancy. 48th Annual Meeting ASDP, Seattle, WA, October 20-23, 2011. Ali L, McDonald C, Ioffreda MD, Clarke LE, Porter W, Helm KF. Use of AntiPhosphohistoneH3 Immunohistochemistry to Determine Mitotic Rate in 3 Melanoma and Its Correlation with the Lymph Node Status. United States and Canadian Academy of Pathology (USCAP) 101st Annual Meeting, Vancouver, BC, Canada, March 17-23, 2012. Evans J, Bayerl M, Acon-Laws M, Malysz J. Discordance of Ki-67 Expression Between Primary Site and Bone Marrow in Patients with B-cell non-Hodgkin Lymphomas. (USCAP) 101st Annual Meeting, Vancouver, BC, Canada, March 17-23, 2012. Bennett JA, Mani H. The Impact of Immunohistochemistry on Turn-aroundTimes in Surgical Pathology Reporting. (USCAP) 101st Annual Mtg,Vancouver, BC, Canada, March 17-23, 2012. Voss S, Crist HS, Mani H. A Cost-Effectiveness Analysis of Thyroid Frozen Sections. (USCAP) 101st Annual Mtg,Vancouver, BC, Canada, March 17-23, 2012. Olson J. Band neutrophil counts in the neonatal population utilizing the Cellavision DM96 system. HMC 4th Annual Resident/Fellow Res Day, Hershey, PA, Mar 9, 2012. Newell J, Patrick S, Clawson G. RNA quality analysis of tumor bank specimens and downstream applicability, EB/ASIP Annual meeting, San Diego, CA, 2012. Publications – Online and book chapters Ali L. Extra medullary hematopoiesis---a web-based quick reference for diagnosis and management designed for dermatologists (In collaboration with Department of Dermatology, Penn State Milton S. Hershey Medical Center), online book chapter. Bennett JA, Bayerl M. Pediatric follicular lymphoma. Low-grade with marginal zone differentiation. Society for Hematopathology case of the quarter (online), May 2012. Invited Presentations National presentations Newell J. Laboratory Instructor, High school lung pathology session at ASBMB/ASIP meeting, 2012. Newell J. Laboratory Instructor, Scientific Sleuthing for High School Teachers, Am Soc for Investigative Pathology meeting, 2012. Regional presentations DelTondo J. The Outpatient Work-Up of Anemia: What Works and What Doesn't? PA Assoc of Pathologists, Harrisburg, PA, April 20-21, 2012. 4 Newell J. Telomerase: the long and short of it. Molecular Diagnostics Laboratory, Johns Hopkins Medical Institute, Baltimore, MD, May 30, 2012. Institutional presentations (Penn State Hershey Medical Center) Bennett J. Lymphoma Tumor Board (interdisciplinary), PSHMC, 2012. Newell J. Infectious Disease Fellow Lecture, Fall 2012. Olson J, Donaldson K. A young girl with chronic hemolysis. Benign Hematology Conference, PSHMC, June 21 2012. Olson J. Design and validation of an automated plasma hemoglobin assay. National Medical Laboratory Professionals Week Continuing Education, PSHMC, April 26 2012. Wells, J. Eleven month old male with aspiration pneumonia, Mortality and Morbidity Conference, Department of Pediatrics, PSHMC, 2011. Wells, J. Five year old male with hypotensive shock, Mortality and Morbidity Conference, Department of Pediatrics, PSHMC, 2011. Wilkinson L. What is Pathology? PA Youth Apprenticeship program, PSHMC, May 2012. Institutional presentations (Penn State Hershey College of Medicine) Olson J. Intro to clinical laboratory. Surgery Clerkship Lectures, Penn State Hershey College of Medicine (PSHCOM), Oct 17, 2011 and June 25, 2012. Mikesell K and Wells J. Transition to Internship. Pathology Residency Focus Group (4th year medical school Island course) Leaders, May 2012. Quality Improvement Lecture Series, Dept. of Pathology Grand Rounds Residents Jennifer Bennett, MD, The Impact of Immunohistochemistry on Turnaround-Times in Surgical Pathology Reporting, Apr 2012 Trevor Caldwell, MD, The Medical Kidney Study Set, Apr 2012 Joseph DelTondo, DO, Resident Wellness Retreat, May 2012 Chad McDonald, DO, Comparison of Methods for Monitoring Platelet Products, Apr 2012 Kael Mikesell, DO, Revising and Improving the GI Study Set, May 2012 Jordan Newell, MD, Development of a gynecologic pathology proficiency exam, May 2012 Sara Ohanessian, MD, Resident Pediatric Study Set, Apr 2012 Jordan Olson, MD, Designing a Rational Antibody Identification Workflow, Apr 2012 Meghan Riley, MD, The Use of C1q Assay in Renal Transplantation, Apr 2012 Sarah Voss, MD, A Cost-effective Analysis of Thyroid Frozen Sections, Apr 2012 Jason Wells, MD, Development and Validation of Controls for Routine Immunocytochemistry, May 2012 5 Lee Wilkinson, MD, Evaluation and Updates of Templates for Autopsy and Gross Protocols and Reports, May 2012 Xuebin Yang, MD, PhD, Donor Specific Antibody Against HLA-DQ Alpha in Post-Transplant Renal Recipients, Mar 2012 Fellows Nestor Dela Cruz, MD, Modification of Recipient Cell Infusion and Transfusion Requirement Form, Mar 2012 Juanita Evans, MD, A Unified Database of Hematopathology Patient Data - Implications for Specimen Triage and Diagnosis, Apr 2012 Ana Watts, MD (presented by F Ruggiero, MD), Resources for Surgical Pathology Signout, Mar 2012 Professional Organization Roles and Committee Memberships National J Olson, MD – Junior member, CAP Practice Management Committee, 2011 – present J Olson, MD – Delegate, CAP resident’s forum, 2010 – 2012 J Wells, MD – Delegate, CAP resident’s forum, 2011 – 2012 L Wilkinson, MD – Resident representative, Am Soc for Clinical Pathology (ASCP) College of American Pathologists Inspection Team Member J Bennett, MD – Surgical pathology, Immunopathology, Histology & Autopsy, Department of Pathology, National Institutes of Health (NIH), 2/2012. J Olson, MD – STAT Lab, Department of Pathology, NIH, 2/2012. J Olson, MD – Blood Bank, Lourdes Hospital, Binghamton, NY, 4/2012. Institutional (Penn State Hershey Medical Center, PSHMC) J Bennett, MD – Member, Surgical Tissue Review Committee, Penn State Hershey K Mikesell, DO – Member, Blood Usage Committee, 2011-present J Newell, MD – Resident member, Child Psychiatry Fellowship program internal review, 2012 J Newell, MD – Peer-selected participant, ACGME CLER site visit, 2012 J Olson, MD – Member, Infection Control Committee, 2010 – 2012 J Olson, MD – Member, Resident Housestaff Quality Improvement Council, 2011 – present M Riley, MD – Graduate Medical Education Committee, 2012 - present 6 Departmental (Department of Pathology and Laboratory Medicine, PSHMC) J Bennett, MD – Awards Committee, 2011-13 J Bennett, MD - Visiting Professor Committee, 2011-13 J Bennett, MD – CAP mock inspector, Histology, 2012 J DelTondo, DO – Visiting Professor Committee, 2011-12 J DelTondo, DO - Resident member, Pathology Residency Program Comm J DelTondo, DO - Co-Chair, Resident Recruitment Luncheon Committee K Mikesell, DO - Resident member, Pathology Residency Program Comm J Newell, MD – Co-Chair, Resident Recruitment Luncheon Committee J Newell, MD– Facilitator/Secretary, Resident Lunch with Progr Directors S Ohanessian, MD – Clinical Pathology Librarian J Olson, MD – Clinical Pathology Quality Assurance and Improvement Comm., 2011 - present J Olson, MD – Lab Automation (ENGEN) task force, 2011-12 J Olson, MD – Automated Testing Laboratory management workgroup, 2011-13 M Riley, MD – Visiting Professor Committee, 2011 - present M Riley, MD – CAP mock inspector, Decedent Care, 2012 S Voss, MD - CAP mock inspector, Clinical Chem & Special Chem, 2012 S Voss, MD – Clinical Pathology Quality Assurance and Improvement Committee, 2011-12 J Wells, MD – Awards Committee. 2010-12 J Wells, MD – Resident member, Pathology Residency Program Committee L Wilkinson, MD – Anatomic Pathology Quality Assurance and Improvement Comm., 2011-12 L Wilkinson, MD – Lead, Resident Core Curriculum Development Comm., 8/2011 - present L Wilkinson, MD – Resident Coordinator, Electronic Dictation Initiative, 7/2011-2/2012 X Yang, MD – Awards Committee, 2011-12 Editorial Boards Ali, L. Member, Int’l J Dermatology, 2012 - present Honors, Awards & Research Funding Chief Residents Joseph A. DelTondo, DO (7/1/2011 - 6/30/2012) Kael V. Mikesell, DO (1/1/2012 - 12/31/2012) Jason M. Wells, MD (1/1/2012 - 12/31/2012) 7 Honors & Awards J DelTondo, DO – Resident Professionalism Award 2012 J DelTondo, DO – First place award, QI project 2012 J Newell, MD – Honorable mention, QI project 2012 Research Funding & Travel Grants Jiang K.– Co-PI, NIH RO1 DK54393-05A2, Signaling regulating protein kinase C beta pre-mRNA splicing, 4/1/2008-3/13/2013 Jiang K. Co-PI, US Government VA Merit, Insulin regulation of protein kinase C beta gene expression and glucose uptake, 4/1/2008-3/13/2013 Olson J. Intraoperative identification of parathyroid tissue utilizing parathyroid hormone assay, Pathology Research Award, 2011. Ali L. PI, Comparing nevi and melanoma by FISH, Pathology Research Award, ($17,527.75), 2011. Frauenhoffer E, Bennett J, Zaino R. Assessment of histologic and prognostic features of low grade advanced stage endometrial carcinoma, Pathology Research Award, ($4,488.50), 2011. Olson J. Crist J, Goldenberg D, Saunders B. Intraoperative identification of parathyroid tissue utilizing parathyroid hormone assay, Pathology Research Award, ($6,700.00), 2011. Olson J, George M, Comito M. Serum potassium concentration changes associated with blood Transfusion in children, Pathology Research Award, ($2,109.00), 2011. Wells J, Mani H, Zander D. Observer reproducibility and impact of the new IASLC, ATS, and ERS classification of lung adenocarcinomas, Pathology Research Initiation Grant, ($6530.00), 2011. Bennett J. Cystic atypical choroid plexus papilloma with a markedly elevated mitotic rate in an infant, Pathology Research Travel Grant, ($1450.00), 2011. Mikesell K. Ependymosarcoma, light and electron microscopic study of a case, Pathology Research Travel Grant, ($1565.00), 2011. Bennett J. The Impact of Immunohistochemistry On Turn-Around-Times In Surgical Pathology Reporting, USCAP 2012, Pathology Research Grant, March 19, 2012. Co-investigator: Dr. Haresh Mani. Wells J. CAP Resident's Forum, USCAP 2012, Pathology Travel Grant, March 19, 2012. Wells, J. Am Assoc of Neuropathologists, Annual Meeting, Chicago, IL, Pathology Travel Grant, June, 2012. Newell J. RNA quality analysis of tumor bank specimens and downstream applicability, EB2012, Co-investigator: Dr. Gary Clawson. Bennett J. Assessment of histologic and prognostic features of low grade advanced stage endometrial carcinoma, Penn State Hershey Medical Center, Dept of Pathology Research Initiation Grant, 2011-13. 8 Teaching and Educational Initiatives MEDICAL STUDENT TEACHING ACTIVITIES Medical Student Pathology Elective mentors: All Residents Medical Student Research mentor: Olson J. PBL Facilitator: CMBMP 711: Cellular and Molecular Basis of Medical Practice, First Year Medical Students, Bennett J. Lab facilitator, Second year medical students GI & Cardiac Pathology Laboratories – Newell J. Renal (2011), Cardiovascular (2011 & 2012), and GI, Liver, Pancreas (2012) Laboratories, Wells J. Renal, GI, Liver, Pancreas and MSK Laboratories – Bennett J. GI & Cardiac Pathology Laboratories): Lynch M. Renal (2011) and MSK (2012) Laboratories – Voss S. High School Student Teaching Activities High School Student Shadowing mentor: Lynch M. High School Student Shadowing mentor: Wilkinson L. PATHOLOGY RESIDENCY PROGRAM TEACHING Lead resident in Surgical pathology, July 2011 – DelTondo J. Lead resident in Surgical pathology, August 2011 – Wells J. Pathology Resident Core Curriculum Lectures: Sinonasal and Middle Ear Lesions, 2012 - Bennett J. Updates in Classification of Lung Adenocarcinomas, 2012 - Wells J. Histiocytic and Granulomatous Pulmonary Lesions, 2012 – Voss S. Odontogenic Lesions, 2012 – Wilkinson L. Orientation Lecture Series Presentations: Normal Histology of Lung, Heart, and Thymus, July 2011 – Well J. Normal Histology of Breast and Placenta, July 2011 - Wilkinson L. Introduction to Neurohistology, 2011 – Bennett J. Normal Histology of Tubular GI tract, liver, and pancreas, July 2011 – Voss S. Normal histology of the endocrine system, HMC – Riley, M. Themed Surgical Pathology Unknown Conference, 2011 Vascular lesions, 2011 – Wells J. Educational Initiatives Newell J. GYN path proficiency and assessment exam for faculty and residents – Developed 2011. 9 Olson J. Laboratory management curriculum for Penn State Hershey Medical Center Pathology Residency program, Developed and Implemented 2011-2012. Wilkinson L. Resident Core Curriculum (2 year repeating cycle) for Penn State Hershey Medical Center Pathology Residency program, Developed and Implemented, 2011-2013. 10
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