TM
NATURAL
PRODUCTS
The Glory Days
As the Baby Boomer generation ages, an unprecedented
number of women have become postmenopausal; an
estimated 6,000 U.S. women reach menopause every day.
Menopausal changes can often be daunting; but, research
supports natural ways to ease symptoms such as hot flashes
and other menopause-related discomforts. INSIDER looks at
classic menopause ingredients like soy, red clover and black
cohosh and introduces new players such as Kwao Kura,
maca, pine bark extract, hops and rhubarb extract.
A Stronghold on Health
When a country is threatened by its enemies, its government
responds with a declaration of war, and the country mobilizes and
prepares for battle. Similarly, when the body is under attack from foreign
bodies and pathogens, the immune system mobilizes to protect
organisms from infection with layered defenses.
The human immune system is an intricate and complex system that
is constantly working to protect our bodies from harm. When depletion
and deficiency occur, the body does not function properly and, as a
result, our health atrophies. Ingredients such as vitamin C, lipoic acid,
colostrum and probiotics support the innate and adaptive immune
functions and can enhance long-term well-being and good health.
Ai/E
10®
M
any substances are known to affect the structure and function of the immune system;
some are more stimulants, while others modulate immune function. The nutritional
ingredient Ai/E 10®, available through Dietary Ingredient Solutions LLC, has been
studied for its ability to stimulate restoration and maintenance of immune function, resulting in
improved immune competence and balance.
BRANDED INGREDIENT
Ai/E
10 ®
Ai/E 10 (AiE10.com) was developed
in 1993 using a combination of infusion
technology developed by Impro Products
Inc. and proprietary information from
Dietary Ingredient Solutions. Infusion
technology works to significantly increase
and specifically focus the molecules
that appear in bovine colostrum or milk
relative to a specified antigen to a level
that allows the recovery and utilization of
the molecules.
The compound is comprised of the <100
kilo Dalton (kDa) immune-active molecules
defensin, granulysin, transfer factors
and mini-cytokines, relative to common
bacterium strains of Staphylococcus
aureus, Streptococcus, E. coli, Salmonella
and Pseudomonas aeruginosa, among
others. Laboratory analysis and clinical
studies have shown the beneficial effects
of Ai/E10 on immunity.
For example, a study conducted by
Solstice Clinical Associates, Tucson,
Ariz., evaluated natural killer (NK) cell
activity of peripheral blood lymphocytes
in 107 patients with documented and
advanced chronic illness, who were
followed for 13.2 months and treated
w i t h A i / E 10 . N K c e l l a c t i v i t y r o s e
significantly (P=<0.001) to a mean of
246 Lytic units (LU), placing them at the
high end of the recognized range for
people in a healthy population.
A n o t h e r s t u d y, c o n d u c t e d b y
Quantum Research Inc. in Scottsdale,
A r i z . , i n v o l v e d 12 h e a l t h y a d u l t s
monitored over 9 0 days as they
consumed 100 mg of Ai/E10 by capsule
t.i.d. Intervention significantly elevated
NK cell activity from a pre-study mean
of 30 LU to a post-study mean of 101
LU. Additionally, Ai/E 10 consumption
significantly reduced “symptoms” on a
general health evaluation.
Immune Consultants, Tucson, Ariz.,
also investigated the impact of Ai/E10, this
time by monitoring the activity of NK cells,
macrophages and tumor necrosis factor
(TNF) activity in vivo for 20 participants,
10 of whom received a placebo and 10 of
whom took 200 mg of Ai/E10 t.i.d., for 15
days. The study group exhibited a clear
“modulated” immune response, elevating
key immune markers occurring in concert
with each other, which is consistent with
observations of the immune system’s ability
to recognize and respond.
B er let t D iet ar y Ingredients also
conducted a study on Ai/E10 , the results
of which were published in the Townsend
Letter, Examiner of Alternative Medicine, in
December 2006. Ai/E10 was compared to other substances marketed for immune support, including
colostrum, maitake, arabinogalactan, lactoferrin and astragalus. The researchers reported all
materials demonstrated immune stimulation; however, Ai/E10 also had a strong, reliable capability to
increase immune surveillance and transfer immunological information among cell groups.
The off-white powder is comprised of <100 kDa refined lacteal complex from skimmed,
pasteurized bovine lacteal secretion, decaseinated by acidification with partial removal of
protein by microfiltration. Ai/E10 can be used as an ingredient in food, as a dietary supplement, or
as an inactive ingredient in homeopathic remedies and drug products; it has been self-affirmed
GRAS (generally recognized as safe). Efficacious daily dosage is 50 mg/serving, minimum two
servings per day. The world’s most effective Immune Response
Modifier for support of the immune system
Effective in small serving sizes. Flexible and synergistic
with many other ingredients.
Visit our website for more information and our clinical
studies www.aie10.com
Shirley Rozeboom 1-714-441-3900
[email protected]
Available In North America
Exclusively From Stauber
INTERNATIONAL
David L. Bergsma
Health Technology Resources, Inc.
1-480-773-6020 [email protected]
Reproduced with permission from Natural Products Insider, August 18, 2008. For electronic usage only.
Not to be printed in any format. ©2008 Virgo Publishing. All Rights Reserved.