ERC Advanced Grants 2016 Last Name First Name BUSSLINGER Meinrad FRIML Jiri HEISENBERG CarlPhilipp TANAKA Elly CARMELIET Peter List of Principal Investigators – Life Sciences domain Host Institution Local Name Forschungsinstitut für Molekulare Pathologie Ges.m.b.H Institute of Science and Technology Austria Institute of Science and Technology Austria Forschungsinstitut für Molekulare Pathologie Ges.m.b.H Host Country Friedrich Miescher Institute for Biomedical Research Friedrich Miescher Institute for Biomedical Research Friedrich Miescher Institute for Biomedical Research Université de Lausanne Host Institution Name The Research Institute of Molecular Pathology Institute of Science and Technology Austria Institute of Science and Technology Austria The Research Institute of Molecular Pathology Flanders Institute for Biotechnology (VIB) Friedrich Miescher Institute for Biomedical Research Friedrich Miescher Institute for Biomedical Research Friedrich Miescher Institute for Biomedical Research University of Lausanne Vlaams Instituut voor Biotechnologie Acronym Panel PlasmaCellControl Transcriptional control of plasma cell development and function LS6 AT ETAP Tracing Evolution of Auxin Transport and Polarity in Plants LS3 AT MECSPEC Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation LS3 AT RegGeneMems Understanding the evolution of regenerationpermissive gene expression and positional memory in Axolotl limb regeneration LS3 BE TECNEC Preclinical concept validation of tumor endothelial cell metabolism for novel antiangiogenic therapy LS4 CH MCircuits Connectivity, plasticity and function of an olfactory memory circuit LS5 CH Epiherigans Writing, reading and managing stress with H3K9me LS2 CH CYCLODE Cyclical and Linear Timing Modes in Development LS3 CH ResiliANT Resilience in ant societies LS8 Rainer GASSER Susan GROSSHANS Helge KELLER Laurent KUHLEMEIER Cris Universität Bern University of Bern CH RESPEC MACPHERSON Andrew J. Universität Bern University of Bern CH HHMM-Neonates Joern Eidgenössische Technische Hochschule Zürich Swiss Federal Institute of Technology Zurich (ETH Zurich) CH SynPlex 2017 European Research Council – http://erc.europa.eu Title AT FRIEDRICH PIEL Host institution refers to institution at time of application 3/04/2017 Reconstruction of Pollinator-Mediated Speciation by Identification and Substitution of Causative Mutations Development of Healthy Host-Microbial Mutualism in Early Life Tailored chemical complexity through evolution-inspired synthetic biology LS8 LS6 LS9 Page 1 of 6 ERC Advanced Grants 2016 Last Name WAGNER First Name Andreas BRÜNING Jens C. BUCHHOLZ Frank BUKAU Bernd CONTI Elena DICK Tobias Peter DIKIC Ivan HIIRAGI Takashi HURT Eduard Christian JENTSCH Thomas KLEIN Ludger LARSSON Nils-Göran List of Principal Investigators – Life Sciences domain Host Institution Local Name Universität Zürich Max-PlanckGesellschaft zur Förderung der Wissenschaften e.V. Technische Universität Dresden Ruprecht-KarlsUniversität Heidelberg Max-PlanckGesellschaft zur Förderung der Wissenschaften e.V. Deutsches Krebsforschungsze ntrum Johann Wolfgang Goethe Universität Frankfurt am Main European Molecular Biology Laboratory Ruprecht-KarlsUniversität Heidelberg Forschungsverbund Berlin e.V. LudwigMaximiliansUniversität München Max-PlanckGesellschaft zur Förderung der Wissenschaften e.V. 2017 European Research Council – http://erc.europa.eu Host Institution Name Host Country Acronym Host institution refers to institution at time of application Title Panel University of Zurich CH NoiseRobustEvo Noise and robustness in the evolution of novel protein phenotypes Max Planck Society DE SYNEME Systems Neuroscience of Metabolism Technical University of Dresden DE GENSURGE University of Heidelberg DE TransFold Max Planck Society DE EXORICO Exosome and ribosome coupling LS1 German Cancer Research Centre DE Redox Relays Detecting, understanding and exploiting intracellular redox signaling relays LS1 DE Ub-BAC Dissecting and targeting ubiquitin networks in the course of bacterial infections LS6 DE SelforganisingEmbryo Self-organisation across the scales in early mammalian development LS3 University of Heidelberg DE Glowsome Encapsulated eukaryotic ribosome assembly LS1 Forschungsverbund Berlin e.V. DE VOLSIGNAL Volume regulation and extracellular signalling by anion channels LS4 University of Munich (LMU) DE TOLERANCE FOOTPRINT Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T Cell Repertoire LS6 Max Planck Society DE mtDNA-CURE Treating mitochondrial disease caused by pathogenic mtDNA mutations LS4 Johann Wolfgang Goethe University Frankfurt am Main European Molecular Biology Laboratory 3/04/2017 Designer recombinases for efficient and safe genome surgery Molecular Biology of Nascent Chains: Cotranslational folding and assembly of proteins in eukaryotes LS8 LS5 LS2 LS1 Page 2 of 6 ERC Advanced Grants 2016 Last Name First Name Host Institution Name Johann Wolfgang Goethe University Frankfurt am Main Max Delbrück Center for Molecular Medicine in the Helmholtz Association Host Country Acronym Title Panel LS9 DE ACETOGENS DE ThermalMR Thermal Magnetic Resonance: A New Instrument to Define the Role of Temperature in Biological Systems and Disease for Diagnosis and Therapy LS7 Max Planck Society DE GeroProtect Developing Geroprotectors to Prevent Polymorbidity LS2 Karlsruhe Institute of Technology DE CRISBREED German Cancer Research Centre DE BARCODEDCELLTRACING Max Planck Society DE NeuroRibo Specialized Ribosomes for Neuronal Protein Synthesis LS5 European Molecular Biology Laboratory European Molecular Biology Laboratory DE SystGeneEdit Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing LS2 Maiken Københavns Universitet DK GlymphEye The Ocular Glymphatic System LS5 Dimitrios Idryma Iatroviologikon Ereunon Akademias Athinon University of Copenhagen Biomedical Research Foundation Academy of Athens (BRFAA) EL LUPUSCARE PRECISION CARE IN SYSTEMIC AUTOIMMUNITY: AN INTEGRATED MULTITISSUE/LEVEL APPROACH FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) LS7 Spanish National Research Council (CSIC) ES Evoland Evolution of regulatory landscapes at multiple timescales LS8 University of Oviedo ES DeAge Pompeu Fabra University ES STEM-AGING Volker NIENDORF Thoralf PARTRIDGE Linda PUCHTA Holger RODEWALD HansReimer SCHUMAN Erin Margaret STEINMETZ Lars NEDERGAARD GOMEZ-SKARMETA Jose Luis LOPEZ OTIN Carlos MUNOZ-CANOVES Host Institution Local Name Johann Wolfgang Goethe Universität Frankfurt am Main Max-DelbrückCentrum für Molekulare Medizin in der HelmholtzGemeinschaft Max-PlanckGesellschaft zur Förderung der Wissenschaften e.V. Karlsruher Institut für Technologie Deutsches Krebsforschungsze ntrum Max-PlanckGesellschaft zur Förderung der Wissenschaften e.V. Host institution refers to institution at time of application Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology MÜLLER BOUMPAS List of Principal Investigators – Life Sciences domain Pura Agencia Estatal Consejo Superior de Investigaciones Científicas Universidad de Oviedo Universitat Pompeu Fabra 2017 European Research Council – http://erc.europa.eu 3/04/2017 Multidimensional CRISPR/Cas mediated engineering of plant breeding Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system Deconstructing Ageing: from molecular mechanisms to intervention strategies Tissue regeneration and aging: the decisive quiescent stem-cell state LS9 LS6 LS4 LS4 Page 3 of 6 ERC Advanced Grants 2016 Last Name First Name List of Principal Investigators – Life Sciences domain Host Institution Local Name Fundación Centro Nacional de Investigaciones Oncológicas Carlos III Host Institution Name Host Country Acronym Host institution refers to institution at time of application Title Panel Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer LS4 Spanish National Cancer Research Centre (CNIO) ES CSI-Fun Helsingin yliopisto University of Helsinki FI BrainDrain Craig Turun yliopisto University of Turku FI MATURATION Olli Turun yliopisto University of Turku FI MULTIEPIGEN BLANCHOIN Laurent Commissariat à l'énergie atomique et aux énergies alternatives FR AAA Adaptive Actin Architectures LS3 BOUSSO Philippe Institut national de la santé et de la recherche médicale FR ENLIGHTEN INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION LS6 PREAT Thomas Centre National de la Recherche Scientifique (CNRS) FR EnergyMemo Dynamic Interplay between Energy and Memory LS5 ACSADY Laszlo Magyar Tudományos Akadémia Kísérleti Orvostudományi Kutatóintézet HU FRONTHAL Specificity of cortico-thalamic interactions and its role in frontal cortical functions LS5 RECHAVI Gidi IL m1ARNA SCHWARTZ Michal IL ImmuneCheckpointsA D YARDEN Yosef French Alternative Energies and Atomic Energy Commission (CEA) National Institute of Health and Medical Research (INSERM) National Center for Scientific Research (CNRS) Institute of Experimental Medicine Hungarian Academy of Sciences Sheba Medical Center Weizmann Institute of Science Weizmann Institute of Science IL onCOMBINE CATTANEO Elena IT HD-DittoGraph WAGNER Erwin ALITALO Kari PRIMMER RAITAKARI Sheba Medical Center Weizmann Institute of Science Weizmann Institute of Science Università degli studi di Milano 2017 European Research Council – http://erc.europa.eu University of Milan 3/04/2017 Translational implications of the discovery of brain-draining lymphatic vessels Age at maturity in Atlantic salmon: molecular and ecological dissection of an adaptive trait Ancestral environmental exposures and offspring health – a multigenerational epidemiologic cohort study across 3 generations Transcriptomic m1A - a new key player in the epitranscriptome arena Immune checkpoint blockade for fighting Alzheimer’s disease Towards evidence-based combinations of approved and novel cancer drugs HD-DittoGraph: a digital human Embryonic Stem Cell platform for Huntington's repeats LS7 LS8 LS7 LS2 LS5 LS7 LS5 Page 4 of 6 ERC Advanced Grants 2016 Last Name First Name List of Principal Investigators – Life Sciences domain Host Institution Local Name Ifom Fondazione Istituto Firc di Oncologia Molecolare Università degli Studi di Perugia Vilniaus Universitetas Erasmus Universitair Medisch Centrum Rotterdam Het Nederlands Kanker Instituut Koninklijke Nederlandse Akademie van Wetenschappen KNAW Host Institution Name Host Country FIRC Institute for Molecular Oncology (IFOM) IT V-EPC Inherited disfunctions of brain microcirculation LS4 University of Perugia IT TREAT-NPM1-AML Improving therapy of NPM1-mutated AML LS7 Vilnius University LT EpiTrack Single-cell temporal tracking of epigenetic DNA marks LS9 Erasmus Medical Center Rotterdam NL Dam2Age DNA Damage and Repair and its Impact on Healthy Ageing LS1 Netherlands Cancer Institute NL SENSIT Sensitivity of human tumors to T cell attack LS6 Royal Netherlands Academy of Arts and Sciences NL IntScOmics A single-cell genomics approach integrating gene expression, lineage, and physical interactions LS2 Acronym DEJANA Elisabetta FALINI Brunangel o KLIMASAUSKAS Saulius HOEIJMAKERS Jan SCHUMACHER Ton VAN OUDENAARDEN Alexander CORANDER Jukka Universitetet i Oslo University of Oslo NO SCARABEE CHIEN Kenneth Karolinska Institutet Karolinska Institute SE 5D Heart Patch ERNFORS Patrik Karolinska Institutet Karolinska Institute SE PainCells HASSELQUIST Dennis Lunds universitet Lund University SE EcoImmuneCosts INGELMANSUNDBERG Magnus Karolinska Institutet Karolinska Institute SE HEPASPHER WARRANT Eric Lunds universitet Lund University SE MagneticMoth ATTWELL David University College London University College London UK BrainEnergy BEARD Paul University College London University College London UK Photoclin BOULTON Simon TelMetab James The Francis Crick Institute The Francis Crick Institute UK BRISCOE The Francis Crick Institute The Francis Crick Institute UK LogNeuroDev 2017 European Research Council – http://erc.europa.eu Host institution refers to institution at time of application 3/04/2017 Title Panel Scalable inference algorithms for Bayesian evolutionary epidemiology A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy Decomposition of pain into celltypes Immunity in Ecology and Evolution: 'Hidden' costs of disease, immune function and their consequences for Darwinian fitness Mimicking liver disease and regeneration in vitro for drug development and liver transplantation Hunting for the elusive “sixth” sense: navigation and magnetic sensation in a nocturnal migratory moth Control of cerebral blood flow by capillary pericytes in health and disease Advanced clinical photoacoustic imaging systems based on optical microresonator detection Telomere metabolism in Genome Stability and Disease The molecular and cellular logic of vertebrate neural development LS8 LS7 LS5 LS8 LS7 LS8 LS5 LS7 LS1 LS3 Page 5 of 6 ERC Advanced Grants 2016 Last Name First Name List of Principal Investigators – Life Sciences domain Host Institution Local Name Host Institution Name University of Cambridge University of Cambridge University of Glasgow Sainsbury Laboratory University of Glasgow Sainsbury Laboratory Colin University of Oxford LUISI Ben ROBERT Daniel SCHAAP Pauline VALLIER Ludovic WIDSCHWENDTER Martin CLUTTON-BROCK Tim HOLYOAKE Tessa KAMOUN Sophien KLEANTHOUS Host Country Acronym UK Group-DynamicsTCB UK ChAMPioN UK BLASTOFF University of Oxford UK OMPorg University of Cambridge University of Cambridge UK VisTrans University of Bristol University of Bristol UK ElectroBee University of Dundee University of Cambridge University of Dundee University of Cambridge UK EVOSOM UK New Chol University College London University College London UK BRCA-ERC 2017 European Research Council – http://erc.europa.eu 3/04/2017 Host institution refers to institution at time of application Title Panel Effects of group dynamics on selection, development and demography in cooperative vertebrates Game-changing Precision Medicine for Curing All Myeloproliferative Neoplasms Retooling plant immunity for resistance to blast fungi Spatiotemporal organisation of bacterial outer membrane proteins Visualising transport dynamics of transmembrane pumps Mechanisms of electroreception in bees and other terrestrial animals Evolution of multicellularity and somatic cell specialization Development of New therapies against cholangiopathies Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control LS8 LS7 LS9 LS1 LS1 LS9 LS8 LS7 LS7 Page 6 of 6
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