Ventral neck mass in a Pembroke Welsh Corgi
Alexander Mesonero DVM
Oceane Aubry DVM
Kellye Joiner DVM, PhD
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History and signalment
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13-yr-old, female, spayed, Pembroke Welsh Corgi
Mass palpated right of the midline on the ventral aspect of the neck.
Clinical signs included hyperactivity, weight loss and urinary incontinence.
T4 levels (T-4: 5.9 ug/dl, normal: 1-4 μg/dl; freeT4: 47 pmol/L, normal: 8-40 pmol/L).
Thoracic radiographs showed no evidence of metastasis.
The mass was approximately 3cm X 1.5 cm, mottled dark-red to tan, hard and gritty on
cut surface.
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Thyroid mass 20 X
200 X
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Thyroid mass 200 X
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Thyroid mass 100 X
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Vascular invasion 200 X
400 X
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Thyroid mass 100 X
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Thyroid mass 50 X
400 X
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Thyroid mass 100 X
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“Immunoreactivity for thyroglobulin”
400 X
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Morphologic diagnosis:
Mixed thyroid carcinoma
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Mixed thyroid tumors
Comprised an admixture of neoplastic epithelial cells and mesenchymal elements.
‰ Mesenchymal component:
I.
Ectopic bone:
A. Heterotopic
B. Metaplastic
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I.
II.
Examples of mixed tumors include:
Mixed mammary tumors
Mixed parathyroid adenoma/carcinoma
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Facts about thyroid tumors
• Incidence in domestic animals:
a) Dogs: Thyroid carcinomas
b) Cats: Thyroid adenomas
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Breeds at high risk; Boxer, Golden retriever, and beagle
• Metastases:
a) Lungs
b) Retropharyngeal and cervical lymph nodes
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References
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Capen CC, Tumors of endocrine glands. In: Tumors in Domestic Animals, ed. Donald J. Meuten,4th ed., p. 638‐654, Blackwell Publishing, Ames, Iowa, 2002
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Ronald K. Myers and M. Donald McGavin, Cellular and tissue responses to injury. In: Pathologic Basis of Veterinary Disease, eds. McGavin MD and Zachary JF, 4th ed., p. 49. Mosby Elsevier, St. Louis, MO, 2007
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