FAQ’S What is IVF? IVF stands for In Vitro Fertilisation. In IVF, the process of fertilisation happens outside of a woman’s body. Eggs are surgically removed and fertilised in a laboratory using sperm that has been given as a sperm sample. Next, the fertilized egg, called an embryo, is surgically implanted into the woman’s womb. Typically one cycle of IVF takes between four and seven weeks. To find out more about IVF treatment, please visit the Human Fertilisation and Embryology Authority website. What is Intra-cytoplasmic sperm injection (ICSI)? Intra-cytoplasmic sperm injection is an in vitro fertilisation procedure in which a single sperm is injected directly into an egg. What is Donor Insemination (DI) Donor insemination is the process of becoming pregnant through donated sperm. What is currently available? At present, women living in Bedfordshire age 23-40 are offered three full cycles of IVF where they have experienced three years of unexplained infertility. What is meant by unexplained fertility? Unexplained infertility is the amount of time that a couple has been trying, unsuccessfully, to become pregnant. Where there is a diagnosed cause of infertility, no waiting period applies. The timescale during the unexplained infertility waiting time allows access to assessments and investigations. Why is the CCG reviewing its policy? On 1 April 2013, clinical commissioning groups assumed responsibility for the planning and purchasing of fertility services including IVF services for people in their area. Shortly before this, in February 2013, NICE (National Institute for Health and Care Excellence) published updated clinical guidance on Specialist Fertility Services, including IVF. Both of these significant changes prompted the CCG to review its current policy on Specialist Fertility Services. Do CCGs have to follow NICE guidance? NICE provides various types of national guidance on promoting good health and preventing and treating ill health. The fertility guidance referred to within this report is one that provides recommendations about the treatment and care of fertility. This type of guidance is not mandatory for commissioners to follow and fund its recommendations. Does this consultation include all fertility interventions? This consultation concerns specialist fertility treatments including intro vitro fertilisation (IVF), intra-cytoplasmic sperm injection (ICSI) and donor insemination (DI). This consultation does not include intrauterine insemination, gamete storage and others funded through individual request route currently or exceptional funding. What does the research say about the success of number of cycles? Several key studies were used as the scientific basis for these proposals. Overall, the results show that the chances of live birth decrease with an increase in the number of previous failed IVF attempts, meaning the chances of successful IVF treatment are lower on the third cycle. For the first cycle of IVF, the chances of live birth are 1 in 4 and decrease to 1 in 5 for two to four cycles. How successful is IVF? The success rate of IVF depends on the age of the woman undergoing treatment as well as the cause of the infertility (if it's known). Younger women are more likely to have healthier eggs, which increases the chances of success. IVF isn't usually recommended for women above the age of 42 because the chances of a successful pregnancy. Outcome statistics/Provider Fresh/Frozen Under 35 years 35-37 38-39 National Average Fresh Frozen Fresh Frozen Fresh Frozen Fresh Frozen Fresh Frozen Fresh Frozen 32.1 21.5 33.9 18.8 32.3 12.4 32.5 23.8 36.3 28.8 23.7 5.6 27.2 20.1 23.0 31.3 26.1 10.2 29.4 35.7 27.0 23.2 27.1 7.3 20.6 17.9 17.0 29.7 21.1 12.7 20.2 18.8 22.6 34.5 12.8 33.3 Barts and London NHS Trust Bourn Hall Clinic (Cambridge) Imperial College Healthcare NHS Trust Oxford Fertility Unit University Hospitals of Leicester 40-42 (not currently NHS funded) 13.2 13.6 11.0 10.0 8.5 3.4 16.1 25.0 16.3 20.8 13.2 0.0 What is the national provision for number of cycles? In 2011, the All Party Parliamentary Group on Infertility produced a report into NHS IVF provision and found that the number of cycles of IVF provided by PCTs averaged at 1.8 nationally. They reported that 39% of PCTs only offered 1 cycle of treatment, 26% offered 2 and 27% offered 3 cycles. The rest 8% of PCTs did not offer any cycle or status was unknown. In summary, 73% of PCTs were offering less than the 3 cycles recommended by NICE guidance. PCTs in the EoE were one of the very few PCTs in the country that offered three cycles. How many people living in Bedfordshire have benefited from IVF? Between 2010 and 2013, BCCG and previously Bedfordshire PCT, commissioned an average of 243 cycles of IVF. What is the cost of a cycle of IVF? Each full cycle of IVF costs, on average, just over £3,000. What is the decision making process? Right now, Bedfordshire Clinical Commissioning Group is inviting people from across Bedfordshire to share their views on proposed changes to IVF services in the area. The process has reached this stage following a policy review. This process has already passed through a number of policy development stages which all policy reviews are subjected to including identification, research, evidence search, scrutiny of evidence, activity and impact assessment, clinical consultation and equality impact assessment. What if I lived somewhere else? Nationally, clinical commissioning groups are in the process of reviewing their policy on Specialist Fertility Services. Bedfordshire CCG is concerned with gathering the views of Bedfordshire residents, GPs and clinicians. What if I am currently receiving IVF? These proposals do not affect people currently going through IVF treatment. When the new policy is approved by the BCCG Governing Body, anyone beginning IVF on or after the implementation date will do so in accordance with the new policy. What if the fertility intervention I need is not covered within the policy? Those patients who do not meet the access criteria can appeal to commissioning bodies for funding under Individual Funding Request scheme. These are mainly for intrauterine insemination, donor insemination, egg and sperm storage for patients undergoing cancer treatments, surgical sperm extraction, preimplantation genetic diagnosis (PGD). Is there other eligibility criteria Other existing eligibility criteria including BMI, smoking status, existing children will be retained. This can be seen online under: Current EoE criteria for IVF Further Information Please note that the following documents are available for you to view online at: www.bedfordshireccg.nhs.uk. Current East of England Criteria for IVF NICE Fertility Guidance (CG156) Specialist Fertility Treatments: A discussion paper for East of England Clinical Commissioning Groups If you would like these documents in hard copy, please contact us on: [email protected] or telephone: 01525 864405
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