Division of Hematology Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 87 DIVISION OF HEMATOLOGY Physician Resources Division Highlights 10 Hematologists (7.45 FTE) Our Patient Care •• 7 full-time The Division continues to see, assess and care for a large number of inpatients and outpatients. For the 2013-14 year, there were 2,107 new patients and 8,964 return patients seen in clinics, 10,826 patients assessed and treated in MDU, 938 inpatient consultations, 656 admissions and 69 blood and marrow transplantations. •• 3 part-time Collaborative clinics at the IWK Health Center and in Moncton and St. John’s continued on a monthly basis. A new program for the management of patients with venous thromboembolism who are prescribed novel oral anticoagulants (NOACs) is under development with the Emergency Department. The Division of Hematology in Halifax has been cited more than once in the last year as having the highest centre accrual for both national and international studies. The Division employs 17 full-time research staff through grant and contract research support. Our Education Dr. Andrea Kew has stepped down as Program Director, Hematology after completing a 6 year term. Under her leadership, the program blossomed with 8 trainees and a laudatory review from the Royal College. Dr. Darrell White has stepped down as Program Director, Internal Medicine after a very successful term. We are very pleased to have him back! Our Research Dr. White was an author of the FIRST trial examining lenalidomide and decadron in patients with myeloma. This was presented at the Plenary Session of the American Society of Hematology Meeting in 2013. Dr. Anderson continues to lead the national CIHR-funded EPCAT II study: Extended Venous Thromboembolism Prophylaxis Comparing Rivaroxaban to Aspirin Following Total Hip and Knee Arthroplasty. Dr. Couban continues to lead the Terry Fox Research Institute study looking at the role of novel biomarkers in patients with MDS and AML. Division members continue to participate in more than 40 active investigator-initiated and industry-sponsored clinical trials in the management of patients with hematologic cancer and venous thromboembolism. 88 Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY Dr. Sudeep Shivakumar has stepped down as Undergraduate Education Director and as leader of the hematology section of the undergraduate curriculum. Welcome to Dr. Mary-Margaret Keating in her new role as Undergraduate Education Director (February 2014) and to Dr. Sudeep Shivakumar in his new role as Postgraduate Program Director (January 2014). Dr. Katherine MacInnes was accepted to the Hematology Fellowship Training Program to start on July 1, 2014. The Division hosted 7 distinguished speakers in 2013-14: including Drs. Margaret Rand, Andrew Davies, Thomas Nevill, David Chui, Dick Wells, Peter Lin and Cyrus Hsia. The Division includes 7 full-time hematologists (Drs. David Anderson, Stephen Couban, Andrea Kew, David Macdonald, Sue Robinson, Sudeep Shivakumar and Darrell White) and 4 part-time hematologists (Drs. Wanda Hasegawa, Ormille Hayne, Mary-Margaret Keating and Andrew Padmos). The team works collaboratively with Capital District Health Authority staff including individuals from nursing, pharmacy, social work, psychological and spiritual supports. The Division is supported by four administrative assistants including team leader, Ms. Cheryl Peever. Welcome back to Sveta Withrow who rejoins our Division. Fond farewell and best wishes to Randi Griffin. New Programs, Partnerships & Innovations Dr. Sudeep Shivakumar is working with Dr. Sam Campbell and the Department of Emergency Medicine to develop a new treatment approach for patients diagnosed with venous thromboembolism who can be treated with a novel oral anticoagulant. This will reduce the number of urgent referrals to the Hematology Clinic. Dr. Couban continues to collaborate with Dr. David Simpson and his colleagues in the Division of General Internal Medicine in redirecting referrals for anemia from the Division of Hematology to the Division of General Internal Medicine since many patients with anemia have problems best assessed and managed by a general internist (approximately 10-15 patients per month). Dr. Mary-Margaret Keating has joined Dr. Sue Robinson in a collaborative Bleeding Disorders Clinic. Dr. Robinson is a recognized national expert in bleeding disorders and has led the CDHA Bleeding Disorders Clinic for many years. Dr. Keating is a welcome addition who will increase our capacity to see patients with bleeding disorders. Work for Nova Scotia Department of Health & Wellness Dr. Anderson continues to co-lead the Nova Scotia Provincial Blood Coordinating Program. Quality & Patient Safety Dr. Wanda Hasegawa is the medical lead of the process at the Capital District Health Authority for the Blood and Marrow Transplant Program to achieve Foundation for Accreditation of Cellular Therapy (FACT) accreditation. This is an international standard which all transplantation centers will be required to achieve in order to continue to perform transplantation procedures. She has also been the medical lead to prepare for accreditation by Health Canada. In addition, Dr. Hasegawa chairs the Hematology Quality Committee and leads quarterly Morbidity and Mortality Rounds. Under her supervision, members of the Division review all deaths of inpatients on the hematology service and other morbidity and mortality events as appropriate. The Division continues to undertake certain types of autologous and allogeneic transplantation on an outpatient basis. In addition, Day 1 transfer of recipients of autologous transplant to Moncton General Hospital continue. Efforts are underway to replicate this process for patients returning to the George Dumont Hospital in Moncton. Division members continue to work with colleagues in nursing, pharmacy and social work to expedite discharges and facilitate appropriate transfers and discharges. Public Education Members of the Division participate in public education endeavors including participating in the advisory boards of patient advocacy groups such as the Aplastic Anemia and Myelodysplasia Society (Stephen Couban) and Myeloma Canada (Darrell White). Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 89 DIVISION OF HEMATOLOGY Our Team Division members provide secondary, tertiary and quaternary care for patients with benign and malignant hematological disorders. This includes the administration of chemotherapy and stem cell transplantation procedures for patients with leukemia, lymphoma and multiple myeloma, along with diagnostic and therapeutic services for patients with thromboembolic and major bleeding disorders. The Division runs an inpatient service at the Victoria General site as well as delivering outpatient care through the Hematology Clinic and Medical Day Unit and through satellite clinics in Moncton, Sydney, St John’s and the IWK Health Centre. 20 Unit/Designation Beds 8A/8B General Hematology & BMT 20 15 Current and historical occupancy rates and bed utilization on Hematology and BMT Nursing Units have been merged to more fully reflect the Hematology Inpatient services in this report. The average occupancy rate (according to midnight census) for 2013-14 was 96.7%. The bed utilization shows an average of 18.1 beds used, with 18.7 available. Figure 1 Hematology Inpatient Bed Average Occupancy Rate by Fiscal Year QEII Health Sciences Centre, 2009 - 2014 120% 95.9% Hematologists provided 24-hour, 7-day / week emergency and on-call inpatient consultation service for the QEII Health Sciences Centre (QEII HSC). Hematologists provided advice and urgent consultation services to physicians in the Maritime Provinces. Hematology Average Bed Utilization by Fiscal Year QEII Health Sciences Centre, 2009 - 2014 Table 1 100% Emergency Coverage Figure 2 Beds Clinical Services There are 20 inpatient beds designated to the General Hematology Service and the Blood and Marrow Transplant (BMT) Service. 94.7% 97.0% 100.5% 96.7% 80% 10 5 0 Total Used Available 2009-2010 16.6 17.3 2010-2011 17.3 18.3 2011-2012 18.3 18.8 Source: STAR Data 2012-2013 18.7 18.6 2013-2014 18.1 18.7 Prepared by DOM Information Office 465 patients were admitted to the Hematology Inpatient Services during 2013-14, representing a 6.8% decrease from the previous year. Additionally, 191 patients were transferred to Hematology care from other parts of the QEII HSC for a total of 656 admissions and transfers for the year. Average Length of Stay (ALOS) was 14.3 days. Figure 3 Hematology Inpatient Admissions and Transfers In by Fiscal Year QEII Health Sciences Centre, 2009 - 2014 60% 800 700 40% 20% 0% 2009-2010 Source: STAR Data 2010-2011 2011-2012 2012-2013 2013-2014 Prepared by DOM Information Office Admissionns and Transfers Issues of appropriateness of care continue to be addressed through quarterly reviews of morbidity and mortality supervised by Dr. Wanda Hasegawa. Inpatient Services (General Hematology and BMT) Percent Occupancy DIVISION OF HEMATOLOGY Issues of Appropriateness of Care 600 500 400 300 200 100 0 Tranfers In Admits Total Source: STAR Data 90 Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 2009-2010 190 504 694 2010-2011 188 484 672 2011-2012 172 472 644 2012-2013 205 511 716 2013-2014 191 465 656 Prepared by DOM Information Office Blood and Marrow Transplant Program (BMT) Figure 6 Hematology Inpatient Admissions Summary Distribution of Patient Residency by Health District QEII Health Sciences Centre, 2013 - 2014 Hematology Inpatient Average Length of Stay (Days) by Fiscal Year QEII Health Sciences Centre, 2009 - 2014 16 The Blood and Marrow Transplant program has served patients throughout the Maritimes since 1992. There were 107 blood and marrow transplants completed in 2013-14, an increase of 9.2% from the previous year. Out of Province: 80 14 14.5 12 13.1 12.5 12.0 14.3 Capital District: 199 Days 10 8 Figure 8 6 4 Blood and Marrow Transplant QEII Health Sciences Centre, 2009 - 2014 Non Capital District: 186 2 120 0 100 2010-2011 Source: STAR Data 2011-2012 2012-2013 2013-2014 Prepared by DOM Information Office Of the Hematology inpatient admissions in 2013-14, 59% were male and 41% were female. 40.0% of admissions came from Nova Scotia Health Districts outside of Capital while an additional 17.2% came from other Atlantic Provinces. These ratios are reflective of the tertiary and quaternary nature of the service. Source: STAR Data Figure 7 60 40 20 0 Hematology Inpatient Admissions Distribution of Patient Residency by Atlantic Province QEII Health Sciences Centre, 2013 - 2014 Autologous Related Allogenic Myeloablative Related Non-Myeloablative Matched Unrelated Myeloablative Matched Unrelated NonMyeloablative Syngenic Transplant Total Newfoundland: 9 Figure 5 80 Prepared by DOM Information Office Transplants 2009-2010 Source: Data Administrator, Oncology Services Prince Edward Island: 33 20092010 47 10 6 7 20102011 51 22 7 9 20112012 52 9 16 7 20122013 48 12 5 16 20132014 62 13 4 6 12 17 25 74 95 1 97 98 107 7 Prepared by DOM Information Office Nova Scotia: 386 Hematology Inpatient Admissions Percent Distribution by Gender QEII Health Sciences Centre, 2013 - 2014 New Brunswick: 36 Female 41% Source: STAR Data Prepared by DOM Information Office Male 59% Source: STAR Data Prepared by DOM Information Office Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 91 DIVISION OF HEMATOLOGY Figure 4 Ambulatory Care Special Service Commitments The figure below depicts a combination of activity on the Hematology Inpatient Consult service and service to the Medical Teaching Unit (MTU) and Internist Emergency Department Call Rotation by division members over the past 5 years. There were 938 inpatient consults at the QEII Health Sciences Centre reported for Hematologists in 2013-2014, representing a 5.0% decrease from the previous year. There were 11,095 patient registrations to the six subspecialty outpatient services during 2013-14, which represents a 2.8% increase relative to the previous year. Of the 2013-14 clinic visits, 19.0% were new consults. Patients undergoing chemotherapy require many return visits. Data includes visits to non-physicians such as nursing and pharmacy. There were an additional 2,740 chart checks performed in 2013-14 not reported in the following figures. Figure 10 109 patients were seen in the Moncton BMT Clinic during 2013-14. Figure 12 Hematology Clinic Visits Moncton Clinics, 2009 - 2014 175 150 125 Visits Figure 9 Hematology Inpatient Consults QEII Health Sciences Centre, 2009 - 2014 Hematology Ambulatory Care Registrations QEII Health Sciences Centre & Cobequid Community Health Centre 2009 - 2014 1,200 100 75 50 12,000 1,054 25 10,000 987 956 896 800 938 Registrations 1,000 # Consullts 600 8,000 0 6,000 New Return Total % New 4,000 2,000 0 400 Autologous B Hereditary Bleeding Disease Blood & Marrow Transplant Deep Vein Thrombosis Hematology Oncology Total 200 0 2009-2010 Source: Physician Services 2010-2011 2011-2012 2012-2013 2013-2014 Prepared by DOM Information Office 2009-2010 2 126 128 1.6% 2010-2011 6 115 121 5.0% 2011-2012 1 153 154 0.6% Source: Divisional Data 20092010 239 585 1,081 2,647 5,087 9,639 20102011 1 415 685 970 3,347 5,265 10,683 20112012 33 443 811 1,137 2,588 5,954 10,966 20122013 33 412 622 1,144 2,064 6,520 10,795 Source: STAR Data 20132014 1 323 657 1,129 2,085 6,900 11,095 2012-2013 1 152 153 0.7% 2013-2014 0 109 109 0.0% Prepared by DOM Information Office 105 patients were seen in the Newfoundland and Labrador BMT Clinic during 2013-14. Figure 13 Prepared by DOM Information Office Figure 11 Hematology Clinic Visits St. John's, Newfoundland, 2009 - 2014 175 Hematology New and Return Ambulatory Care Registrations QEII Health Sciences Centre & Cobequid Community Health Centre 2009 - 2014 150 125 14,000 # Visits 12,000 10,000 Regiistrations DIVISION OF HEMATOLOGY Inpatient Consultations 75 8,000 50 6,000 25 4,000 0 2,000 New Return Total % New 0 New Return Total % New Source: STAR Data 92 100 Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 2009-2010 2,238 7,992 10,230 21.9% 2010-2011 2,890 8,555 11,445 25.3% 2011-2012 2,570 9,539 12,109 21.2% 2012-2013 2,014 8,781 10,795 18.7% 2013-2014 2,107 8,988 11,095 19.0% Prepared by DOM Information Office 2009-2010 18 144 162 11.1% Source: Divisional Data 2010-2011 9 109 118 7.6% 2011-2012 21 95 116 18.1% 2012-2013 17 122 139 12.2% 2013-2014 18 87 105 17.1% Prepared by DOM Information Office Wait Times & Outpatient Through-put All patients referred to the Division of Hematology are triaged centrally by a Hematologist. Urgency is assigned using criteria in the table below. It should be noted that effective October 2009 the division began a pilot providing written advice to referring physicians in place of a clinic visit for certain less-urgent referrals. Figure 14 Hematology Clinic Visits IWK PNC Hematology Clinics, 2009 - 2014 70 60 AAxis Title 50 40 30 20 10 0 New Return Total % New Source: Meditech 2009-2010 27 17 44 61.4% 2010-2011 35 31 66 53.0% 2011-2012 24 16 40 60.0% 2012-2013 30 12 42 71.4% 2013-2014 30 17 47 63.8% Prepared by DOM Information Office Guidelines for Triage of New Referrals to Hematology Outpatient Clinics Standard Wait Time Emergent (C1) Examples include: –– New diagnosis of acute Leukemia –– Severe thrombocytopenia –– Severe Anemia –– Severe Leukopenia Within 48 hours Urgent (C2) Examples include: –– New diagnosis of Lymphoma/Hodgkin’s disease Within 2 weeks (14 days) Semi-urgent (C3) Examples include: –– New diagnosis of Myeloma –– Moderate Anemia, Moderate Thrombocytopenia –– New diagnosis of chronic myeloid leukemia (stable) Within 6 weeks (42 days) Non-urgent (C4) Examples include: –– Homozygous HFE C282Y Hemachromatosis –– Mild cytopenias –– Duration of anticoagulation –– New diagnosis of chronic lymphocytic leukemia (stable) –– Personal or Family History of previous thrombosis Within 13 weeks (90 days) Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 93 DIVISION OF HEMATOLOGY 47 patients were seen in the High-Risk Pregnancy Clinic for Women with Hematological Disorders at the IWK Health Centre in 2013-14. Figure 17 Hematology Emergent Consult Ambulatory Care Clinic Average Wait Time (Days) by Quarter QEII Health Sciences Centre, 2012 - 2014 Of the outpatient clinic registrations in 2013-14, 38.5% reside in Nova Scotia Health Districts outside of Capital while an additional 5.5% came from outside Nova Scotia. Hematology New Semi-Urgent Consult Ambulatory Care Clinic Average Wait Time (Days) by Quarter QEII Health Sciences Centre, 2012 - 2014 3 50 Figure 19 40 Days Days 2 Hematology Clinic Registrations Summary Distribution of Patient Residency by Health District QEII Health Sciences Centre, 2013- 2014 30 20 1 10 0 Average Wait Time Standard Wait Time Count Minimum Wait Maximum Wait % Within Standard Q1 12-13 1.0 2 74 0 10 95% Q2 12-13 1.0 2 47 0 11 94% Q3 12-13 1.2 2 51 0 18 92% Q4 12-13 1.6 2 54 0 30 94% Q1 13-14 0.7 2 82 0 10 96% Source: PHS Data Q2 13-14 1.2 2 70 0 26 91% Q3 13-14 0.9 2 60 0 6 93% Q4 13-14 0.5 2 62 0 4 97% Prepared by DOM Information Office Figure 16 0 Average Wait Time Standard Wait Time Count Minimum Wait Maximum Wait % Within Standard Out of Province: 607 Q1 12-13 29.2 42 160 0 189 83% Q2 12-13 33.1 42 163 1 111 74% Q3 12-13 29.9 42 135 2 108 82% Q4 12-13 35.4 42 169 2 387 80% Q1 13-14 34.8 42 176 1 348 76% Source: PHS Data Q2 13-14 33.9 42 146 1 168 78% Q3 13-14 28.7 42 158 0 102 82% Q4 13-14 32.4 42 144 1 123 79% Hematology New Urgent Consult Ambulatory Care Clinic Average Wait Time (Days) by Quarter QEII Health Sciences Centre, 2012 - 2014 Source: STAR Data 120 100 10 Days 80 5 60 40 20 0 Average Wait Time Standard Wait Time Count Minimum Wait Maximum Wait % Within Standard 94 Non Capital District: 4,269 Prepared by DOM Information Office Hematology New Non-Urgent Consult Ambulatory Care Clinic Average Wait Time (Days) by Quarter QEII Health Sciences Centre, 2012 - 2014 15 Source: PHS Data Capital District: 6,219 6 219 Figure 18 Days DIVISION OF HEMATOLOGY Figure 15 Q1 12-13 12.1 14 133 0 45 68% Q2 12-13 9.2 14 107 0 25 88% Q3 12-13 11.9 14 119 0 98 69% Q4 12-13 13.6 14 114 0 62 73% Q1 13-14 12.7 14 123 1 58 76% Q2 13-14 11.7 14 131 1 62 79% Q3 13-14 14.0 14 89 0 302 76% Q4 13-14 12.5 14 118 1 53 65% Prepared by DOM Information Office 0 Average Wait Time Standard Wait Time Count Minimum Wait Maximum Wait % Within Standard Source: PHS Data Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY Q1 12-13 85.0 90 117 0 219 60% Q2 12-13 89.8 90 177 1 389 61% Q3 12-13 75.4 90 189 2 377 71% Q4 12-13 61.1 90 186 1 407 81% Q1 13-14 83.1 90 145 6 405 70% Q2 13-14 83.6 90 190 1 506 70% Q3 13-14 76.6 90 246 2 520 69% Q4 13-14 100.6 90 201 2 544 65% Prepared by DOM Information Office Prepared by DOM Information Office Education Most ambulatory Hematology care at the QEII HSC occurred in the Medical Day Unit. This activity accounted for 65.9% of the activity of the MDU during the year. There were 16,576 patients registered in five subspecialty programs in the Medical Day Unit in 2013-14, representing a 0.6% decrease in total activity from the previous year. All hematologists were involved in the provision of medical education during the year. Figure 20 Hematologists provided 4 weeks of attending service on the MTU, 35 shifts as Internist on-call to the Emergency Department during the 2013-14 academic year. Figure 22 Hematology Medical Day Unit Registrations Summary Distribution of Patient Residency by Health District QEII Health Sciences Centre, 2013 - 2014 Hematology Medical Day Unit Proportion of Total Medical Day Unit Registrations QEII Health Sciences Centre, 2009 - 2014 18,000 Undergraduate Medical Education 16,000 14,000 Registrations 12,000 Out of Province: 1,126 10,000 Capital District: 7,028 8,000 The division provided 32 core and elective rotations and over 136 hours of undergraduate education. Postgraduate Medical Education 6,000 4,000 2,000 0 Total Medical Day Unit Total Hematology Percent Hematology 2009-2010 13,068 9,388 71.8% 2010-2011 14,518 10,124 69.7% 2011-2012 15,761 10,650 67.6% Source: STAR Data 2012-2013 16,678 11,648 69.8% Non Capital District: 2,764 2013-2014 16,576 10,918 65.9% Prepared by DOM Information Office Figure 21 Source: STAR Data Prepared by DOM Information Office 58 residents rotated through the Hematology service during the 2013-14 academic year, including 19 externals from Pathology, Nuclear Medicine, Family Medicine, Hematologic Pathology, Anaesthesia, Radiation Oncology and Neurology residency training programs. Division members delivered 9 hours of Academic Half Day teaching, 9 hours of CaRMS Selection Process and 10 hours as examiners for the Resident OSCE in the 2013-14 academic year. Hematology Medical Day Unit Ambulatory Care Registrations QEII Health Sciences Centre, 2009 - 2014 14,000 12,000 Subspecialty Medical Education R Registrations 10,000 8,000 6,000 4,000 2,000 0 MDU Bone Marrow MDU Oncology MDU Apheresis Bone Marrow MDU Apheresis Hematology MDU Hematology Total Source: STAR Data 20092010 0 0 46 182 9,160 9,388 20102011 0 35 6 149 9,934 10,124 20112012 0 210 8 179 10,253 10,650 20122013 1 588 26 159 10,874 11,648 20132014 298 3,407 279 420 6,514 10,918 Prepared by DOM Information Office The Division of Hematology offers a two-year Hematology residency training program, fully accredited by the Royal College of Physicians & Surgeons of Canada. Dr. Sharif completed Hematology residency training December 17, 2013 and is now working at George Dumont Hospital, Moncton, NB. Dr. Zed completed Hematology residency training June 30, 2014 and is now working at Saint John Regional Hospital, Saint John, NB. Dr. Katherine MacInnes was accepted to the Hematology Fellowship Training Program to start on July 1, 2014. Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY 95 DIVISION OF HEMATOLOGY Medical Day Unit (MDU) DIVISION OF HEMATOLOGY Continuing Medical Education Hematologists were active in the provision of continuing medical education, with 31 sessions presented to general practitioners, specialists and other trainees in 2013-14. Research Administration Division members continue to maintain positions of prominence within the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG). Members are also leaders in clinical research in thromboembolic and major bleeding disorders Hematologists performed the following administrative activities: 16 peer reviewed, 1 non-peer reviewed publications and 16 abstracts were presented at National/International scientific meetings in 2013-14. •• Division members act as Directors/Head/Chairs for: Hematologists provided referee and editorial services for 4 journals/granting agencies during 2013-14. The Division generated $2,716,794 in research grants and industry contracts during 2013-14. •• Division Head, including all responsibilities of the position. –– –– –– –– –– –– –– –– –– –– –– –– –– –– 96 Department of Medicine Compendium of Divisional Activity 2013-2014 — divisIon of HEMATOLOGY Director, Bleeding Disorder Program Medical Director, BMT Program Quality Director, BMT Program Chair, Hematology Research Finance Committee Chair, Hematology Residency Training Committee Chair, Hematology Tumor Site Group Chair, Hematology Morbidity & Mortality Committee Director, Postgraduate Medical Education Committee Director, Thrombosis and Anticoagulation Program Director, Undergraduate Medical Education Chair, Resident Research Committee Co-Chair, Research Ethics Board Chair, Thrombosis Canada Fellowship Committee Director, High Risk Obstetrics Clinic
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