The practice-orientated research clinician – reality or myth? Prof Anthony W Bateman Importance of topic for practice based evidence (n>1000 psychotherapists) Importance of topic Category % Mechanism of change Intervention and process 88.5 Therapeutic relationship Outcomes 84.4 Effective training Professional and practice 78.4 Use of reflection Professional and practice 77.3 Therapeutic ruptures Intervention and process 76.4 Tailoring therapy Therapeutic imputs 75.9 Symptoms Outcomes 74.6 Psychotherapy with eating disorders/professional group (%) ( N=118) Couns Psychol Social work Nutrition Nurse Dr Other 12 Step 2.7 8.3 0 0 0 20 0 Alternative 2.7 0 0 0 50 0 10.7 CBT 29.7 41.7 11.1 40.0 0 20.0 17.9 Eclectic 45.9 41.7 51.9 40.0 25.0 20.0 39.3 EMDR 0 0 3.7 0 0 0 0 Feminist 5.4 0 0 0 0 0 3.6 Hypno 2.7 0 0 0 0 0 0 IPT 2.7 0 3.7 0 0 0 0 Psychodynamic 0 0 0 0 0 40.0 0 The Impact of Therapists on Treatment Outcome Odds of a clinical episode in MBT by therapist Variance due to Tx and Therapists in NIMH study of Depression (CBT & IPT) Kim et al., 2006, Psychother Res, 16:161 Variable Treatment Therapist BDI 0% 5% to 11% HRSD 0% 1% to 12% HSCL-90 0% 3% to 10% GAS 0% 8% to 12% Variance due to therapists in practice Wampold & Brown, JCCP, 2006 581 Therapists, 6146 heterogeneous patients Diagnosis, degree, experience: 0% variance Medication: 1% (but also dependent on psychotherapist) Provider: 5% Top quartile produced twice the effect of the lowest quartile in subsequent year Impact of individual therapists in routine practice Okiishi et al. 2006 (J Clin Psychol 62:9, 1157) 6,499 patients seen by 71 therapists therapists had to see at least 15 clients on average saw 92 number of sessions: range 1-203; mean 8.7 therapists saw equivalent range of clients in terms of disturbance & presentation HLM used to compare ‘trajectories’ (recovery curves) of patients using OQ45 Clients of Some Therapists Improve Faster or Slower Than Others Session number Slope of Improvement Across Therapists Unaffected by: • therapist experience • gender • type of training counselling psychology, clinical psychology, social work, marital/family therapist • orientation CBT, humanistic, psychodynamic Outcomes for Best and Worst Performing Therapists recovered improved deteriorated top 10% therapists 22.4% 21.5% 5.2% bottom 10% therapists 10.6% 17.4% 10.5% Incidence of Harmful Effects estimates are that 5-10% of therapy clients deteriorate • across all orientations, client groups, modalities • in RCTs of ‘empirically supported treatments’ rates higher than in control groups • e.g. NIMH reanalysis (Ogles et al. 1995) • 13/162 (8%) deteriorated, all in active treatments in Lambert’s work therapists tend to be poor at: predicting who will do badly recognising failing therapies Do no harm… outcomes informed care Most therapists see themselves as better than average: Dew & Riemer (2003, 16th Annual Research Conference, University of South Florida) • 143 counselors asked to grade their job performance on scale from A+ to F • 66% rate themselves as A or better • none rated themselves as below average Outcomes informed care may be a critical way of linking the EBP approach and practice based evidence Therapist predicted treatment success compared to actual treatment outcomes after psychotherapy Hannan, C et al (2005) A Lab Test and Algorithms for Identifying Clients at Risk for Treatment Failure. Journal of Clinical Psychology 61, 155-163 500 450 400 350 Number 300 Therapist predicted outcome Actual Treatment Outcome 250 200 150 100 50 0 Positive No Change Deteriorated Percentage of patients, by site, who achieve clinically meaningful improvement within median treatment length Hansen, N et al The Psychotherapy Dose-Response Effect and its Implications for Treatment Delivery Services. Clin Psychol Sci Prac 9:329–343, 2002 Site Sample Size Median sessions % Recovered % Improved Employee Assistance 3,269 3 7.4 18.3 University Counseling 1,188 4 5.9 15.2 Local HMO 595 2 5.7% 14.3 National HMO 536 4 9.1 24.4 Training CMH 123 8 6.5 20.3 State CMH 361 4 5.8 17.7 Total 6,072 6072 3 6.5 16.6 Randomized trial on the effectiveness of long and short-term psychodynamic psychotherapy and solution-focused therapy (Knekt et al., 2008 Psychol Med, 38(5), 689-703. • • A total of 326 outpatients (20-46 years) with mood (84.7%) or anxiety disorder (43.6%) or both Three treatment groups long-term psychodynamic psychotherapy (up to 3 years), short-term psychodynamic psychotherapy (5-6 months), solution-focused therapy (up to 8 months) • A randomized trial with a 3-year follow-up, carried out from 1994-2005. • Primary outcome depressive symptoms measured by self-report (BDI) and observer-rated (HDRS) RCT of long and short-term psychodynamic psychotherapy and solution-focused therapy for mixed anxiety & depression: HDRS 18 SFT (n=97) 17 SPP (n=101) 16 LTP (n=128) Mean HDRS 15 14 13 12 11 10 9 8 0 7 Months 12 36 Source (Knekt et al., 2008) Psychol Med, 38(5), 689-703. RCT of the effectiveness of long and short-term psychodynamic psychotherapy and solution-focused therapy: BDI 21 19 SFT (n=97) 17 SPP (n=101) LTP (n=128) Mean BDI 15 13 11 9 7 5 0 3 7 9 Months 12 18 24 36 Source (Knekt et al., 2008) Psychol Med, 38(5), 689-703. Recovery from depressive symptoms (BDI) and no auxiliary treatment Knekt et al.Nord J Psychiatry 2013;67:59–68. Adequate work ability (Work Ability Index ,WAI36) and no auxiliary treatment. Conclusions concerning evidence base for long term psychodynamic therapy • Good pre-post treatment effects • Moderate between group effects (promising) • Hard to demonstrate superiority of intensive over non-intensive treatments Probably measuring wrong things And not for long enough • Most promising Anorexia, complex depression, PD • Weaker evidence Anxiety, somatic problems, simple depression Developing the research based practice clinician Effect of service re-organisation on outcomes in PD Criticisms from clinicians Research population differs from clinical population Reliance on diagnostic criteria Inappropriate outcomes Lack of clinical detail eg moderators Outcome scales do not reflect functioning Evidence based treatment does not equal evidence based practice Criticisms from researchers Clinical decision making unreliable and unrepeatable Integrating research evidence with clinical expertise too varied Patient moderators used by clinicians impossible for generalisation No consistency over time and no validity that clinical decisions make a difference Eclectic therapy is not transferable across clinicians Poor collection of systematic observations Moderators of outcomes Limited information e.g. gender, ethnicity, age No information about how moderators work within a treatment of across treatments Which patients are affected Are all patients affected Is moderator a proxy for e.g. ethnicity for patient/therapist mismatch Effects may be due to highly correlated component eg stress level of group, severity, social issues Introducing practice orientated research Patient problems A chore Usefulness for them Focus and attention Social responsibility Clinician concerns Usefulness for treatment Sensitivity to monitoring Time Interference with treatment process Practicality and logistics Reducing the Harmful Effects of Psychotherapy: The work of Lambert (2009) Across studies the rate of observed deterioration in psychotherapy was 10-25% with young people Some therapists have rates of deterioration of around 50% and their treatment is NEVER associated with recovery Introduction of outcome tracking (session by session monitoring) Early warning when patient goes off trajectory Therapists randomized to feedback vs no-feedback Deterioration reduced by 50% Recovery improves by 50% Average therapy is shorter Patients who show early negative response receive longer and more effective treatment Using Client Feedback to Improve Couple Therapy Outcomes: A Randomized Clinical Trial in a Naturalistic Setting. Anker, Morten; Duncan, Barry; Sparks, Jacqueline Journal of Consulting & Clinical Psychology. 77(4):693-704, August 2009. 2 Patient-Focused Research: Using Patient Outcome Data to Enhance Treatment Effects. Lambert, Michael; Hansen, Nathan; Finch, Arthur Journal of Consulting & Clinical Psychology. 69(2):159-172, April 2001. Patient-Focused Research: Using Patient Outcome Data to Enhance Treatment Effects. Lambert, Michael; Hansen, Nathan; Finch, Arthur Journal of Consulting & Clinical Psychology. 69(2):159-172, April 2001. 2 Time to improvement using reliable change index. Patient-Focused Research: Using Patient Outcome Data to Enhance Treatment Effects. Lambert, Michael; Hansen, Nathan; Finch, Arthur Journal of Consulting & Clinical Psychology. 69(2):159-172, April 2001. Time to recovery measured by clinically significantly improved criteria. 2 Pattern of Change: Sum of Mood Ratings and Hours Spent Outside of the House During a 31-Week Treatment Clinical Practice as Natural Laboratory for Psychotherapy Research: A Guide to Case-Based Time-Series Analysis. Borckardt, Jeffrey; Nash, Michael; Murphy, Martin; Moore, Mark; Shaw, Darlene; ONeil, PatrickAmerican Psychologist. 63(2):77-95, February/March 2008. 2 Directional and Temporal Relationship of Change in Mood With Change in Social Engagement During Therapy Clinical Practice as Natural Laboratory for Psychotherapy Research: A Guide to Case-Based Time-Series Analysis. Borckardt, Jeffrey; Nash, Michael; Murphy, Martin; Moore, Mark; Shaw, Darlene; ONeil, Patrick American Psychologist. 63(2):77-95, February/March 2008. 2 Opportunistic Benefit Study: Mean Weekly Blood Pressure (BP) Readings (Taken at Work) Across Baseline, Medication-Only, and Medication-Plus-Psychotherapy Phases Clinical Practice as Natural Laboratory for Psychotherapy Research: A Guide to Case-Based Time-Series Analysis. Borckardt, Jeffrey; Nash, Michael; Murphy, Martin; Moore, Mark; Shaw, Darlene; ONeil, Patrick. American Psychologist. 63(2):77-95, February/March 2008. 2 Hypothetical Results Demonstrating a Typical Data Stream Encountered in Time-Series Studies: A Five-Week Intervention for Pain Clinical Practice as Natural Laboratory for Psychotherapy Research: A Guide to Case-Based Time-Series Analysis. Borckardt, Jeffrey; Nash, Michael; Murphy, Martin; Moore, Mark; Shaw, Darlene; ONeil, Patrick. American Psychologist. 63(2):77-95, February/March 2008. 2
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