Evaluation of the efficacy of a combination ® ® of CircoFLEX and MycoFLEX in a farm Chuanxian Hua , Tao Ma , Yixiao Lin , John Kolb , Liande Zhu 1 2 2 2 2 Jiangxi Lvhuan Farming Group; 2Boehringer Ingelheim Int’l Trading (Shanghai) Co. Ltd., Beijing100004, China 1 FCRADWG 3.00 720 2.90 700 2.80 680 2.70 660 2.60 640 2.50 620 2.40 Performance records were collected for the before and after periods. The following parameters were recorded per batch: weaning weight at 25-day age, market weight, mortality in both nursery and finishing pigs, Feed Conversion Ratio (FCR), Average Daily Weight Gain (ADWG) and drug cost per finisher. Aug 15 Jul 15 Jun 15 May 15 Apr 15 Mar 15 Feb 15 Jan 15 Dec 14 Nov 14 Oct 14 Sep 14 Aug 14 Jul 14 Jun 14 May 14 Apr 14 Mar 14 Feb 14 Jan 14 Dec 13 580 Nov 13 2.20 Oct 13 600 batches Figure 2: The mortality of different batches recorded by month. 16 % 14 % 12 % 10 % mortality This study was conducted in a commercial farrow-to-finish farm with a herd size of 1000 sows in Jiangxi province in China. This farm had been vaccinated with a local PCV2 vaccine (a Cap protein subunit vaccine based on baculovirus vector; two doses at 14 and 35-days of age) and an imported Mycoplasma hyopneumoniae vaccine (two doses at 7 and 21-days of age), with slaughter pigs sold from September 2013 to August 2014. Beginning September 2014 through August 2015, pigs were sold that were vaccinated with the combination of Ingelvac MycoFLEX® and Ingelvac CircoFLEX®, 1 dose of 2.0 ml (1.0 mL Ingelvac CircoFLEX® and 1.0 ml of Ingelvac MycoFLEX®, at 14-days of age) to immprove performance, convenience and compliance. 2.30 Sep 13 MATERIALS AND METHODS ADWG PCVD (Porcine Circovirus type 2 (PCV2) diseases) and EP (enzootic pneumonia) are two of the economically important swine diseases in China. Single or co-infections with these pathogens are associated with several clinical signs, such as postweaning multisystemic wasting syndrome (PMWS), stunting, cough, diahrea, dermatitis and nephropathy. The purpose of this study was to evaluate the efficacy of the combination of Ingelvac CircoFLEX® and Ingelvac MycoFLEX® in a farm. Figure 1: The ADWG and FCR of different batches recorded by month. FCR INTRODUCTION 8 % 6 % 4 % 2 % Aug 15 Jul 15 Jun 15 May 15 Apr 15 Mar 15 Feb 15 Jan 15 Dec 14 Nov 14 Oct 14 Sep 14 Aug 14 Jul 14 Jun 14 May 14 Apr 14 Mar 14 Feb 14 Jan 14 Dec 13 Nov 13 Oct 13 The changes before and after use of the combination in mortality, FCR and ADWG of different batches are showed as follows (figure 1 and 2). The mortality was reduced from an average of 11.2 % to 3.9 %, and FCR was reduced from an average of 2.82 to 2.51. The ADWG was improved an average of from 652.3 g/d to 705.7 g/d, and the drug cost also reduced by an average of 13.4 yuan (2.2 USD). 0 % Sep 13 RESULTS batches CONCLUSION In this farm, the freshly mixed combination of Ingelvac MycoFLEX® and Ingelvac CircoFLEX® reduced the mortality rate, FCR and drug cost, and improved ADWG by 53.4 g/d, which illustrated the superior efficacy of the combination. Additionally, the combination made vaccination easier for both people and pigs by reducing stress with a single-shot injection of the two different vaccines.
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