CAMPBELL BIOLOGY How do we study science? TENTH EDITION Reece • Urry • Cain • Wasserman • Minorsky • Jackson 1 First a scientist identifies a problem or question Why do certain cells turn into cancer cells? Is this substance hazardous to your health? Make Observations Scientific Inquiry Dr Burns NVC Then the scientist formulates a hypothesis Then the scientist designs an experiment to study the problem © 2014 Pearson Education, Inc. Scientific Method 1. Observation – Observe some aspect of nature 2. Investigate what others have found, ask critical questions Scientific Method 1. Observation – Observe some aspect of nature 3. Develop a hypothesis – educated guess to make a prediction 4. Design experiments to test your predictions 5. Repeat experiments 6. Analyze the data 7. Draw conclusions 8. Report the method, data, results and conclusions Scientific Method 2. Investigate what others have found, ask critical questions Scientific Method 3. Develop a hypothesis 1 Hypothesis A hypothesis is a possible explanation for an observation. Hypothesis Are there some questions that can not be answered by science? A hypothesis -must be tested to determine its validity -is often tested in many different ways -allows for predictions to be made Experimental Design Search the available databases to find out what other scientists have done, how they did their research and their results. Design the experiment to test one variable at a time. Set up a control group which is identical to the experimental group except without the one variable being tested. Repeat the experiment to get statistically significant data. Controlled experiments Constants – all the factors that are kept the same in the experiment Control Group and Experimental Group – all the constants are the same, only the independent variable differs between the two groups Controlled experiments A independent variable is something that is changed to see how that change effects the study. How many variables should you test at one time? The dependent variable is measured, it may change as a result of the independent variable Example Hypothesis: Artificial sweeteners are safe to eat The researchers choose the mouse as a model to test the safety of the additive (Why not humans? Are mice good models?) 2 Example They divide a group of similar mice (all the same age, sex, raised the same way) into two groups. Half the animals are the control group, they are fed the normal diet, the other half are the experimental group = they are fed a diet of 50% normal food and 50% artificial sweetener (Is this a lot?) Results One third of the test group developed bladder cancer None of the control group developed bladder cancer. Cannot accept the hypothesis that the additive is safe at this level of consumption. Does Smoking Cause Cancer One way to study a problem is to look at epidemiology evidence. Look at cancer rates over time, correlate cancer rates with events and changes that also occur during that period. What would have happened if we had looked at a different dependent variable, hyperactivity, would we have missed the bladder cancer? Theories in Science In the context of science, a theory is Broader in scope than a hypothesis General, and can lead to new testable hypotheses Supported by a large body of evidence in comparison to a hypothesis © 2011 Pearson Education, Inc. 3 Figure 1.21a 4
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