Meiosis and Mitosis Bio 250: Genetics Dr. Ramos The nucleus (Information and administrative center of the cell) Nucleus – houses the genetic material • During non-divisional phases the genetic material is uncoiled and dispersed in the nucleus. • During division chromatin condenses into chromosomes. Chromosomes • Distinctive shapes and lengths. • Constricted region called centromeres. Karyotype Physical appearance of different pairs of homologous chromosomes. Mitosis • Goal: Create two daughter cells that are genetically identical to the parent cell. • Which cells: somatic cells (no gametes) Interphase Prophase Anaphase Telophase Metaphase Cytokinesis Sexual reproduction • Advantageous – Novel combination of genes in each generation. – Each individual in a population of sexually reproducing organisms has a distinct genetic composition. Highly diverse offspring! Meiosis • Important during production of gametes or spores with haploid set of chromosomes. • Sexual reproduction – 2 haploid gametes combine = diploid • Consists of a reduction division and an equational division. Mitosis vs. Meiosis Meiosis I Prophase I • Tetrad or bivalent formation (pairs of homologous chromosomes come together). • Recombination can occur between any two chromatids within this tetrad structure. • Chiasmata – visible structure shows crossover. Essential for accurate meiosis. Meiosis I • Metaphase I – tetrad moves metaphase plate. • Anaphase I – Random pull of half of tetrad to the poles. • Telophase I – nuclear membrane around dyads. Meiosis II • Essential to insure each gamete receives one chromatid from the original tetrad. Spermatogenesis and Oogenesis • Meiotic events similar but key difference between males and females. • Spermatogenesis Spermatogenesis and Oogenesis • Oogenesis Glossary Sheet • Terms you should know from this lecture: • Terms you should know for the next lecture: Product Law Chi-Square analysis Sum Law
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